Mycobacterium tuberculosis, Mycobacterium bovis, esterase lipH lipI Rv1400c
Esterase that can hydrolyze short-chain esters with the carbon chain containing 2 to 12 carbon atoms. In vitro, pNP-butyrate is the preferred substrate. Rv1400c gene lipI MTCY21B4.16c Orf 16 of MTCY21B4 old myctu-lipas. || There are more than 1000 strains. Other Uniprot entries and list of strains can be found with the link: Other strains
Family : Hormone-sensitive_lipase_like
Block : H
Position in NCBI Life Tree : Mycobacterium tuberculosis
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Actinobacteria [phylum] N E > Actinobacteria [class] N E > Corynebacteriales N E > Mycobacteriaceae N E > Mycobacterium N E > Mycobacterium tuberculosis complex N E > Mycobacterium tuberculosis N EMPSLDNTADE KPAIDPILLK VLDAVPFRLS IDDGIEAVRQ RLRDLPRQPV HPELRVVDLA IDGPAGPIGT RIYWPPTCPD QAEAPVVLYF HGGGFVMGDL DTHDGTCRQH AVGADAIVVS VDYRLAPEHP YPAAIEDAWA ATRWVAEHGR QVGADLGRIA VAGDSAGGTI AAVIAQRARD MGGPPIVFQL LWYPSTLWDQ SLPSLAENAD APILDVKAIA AFSRWYAGEI DLHNPPAPMA PGRAENLADL PPAYIAVAGY DPLRDDGIRY GELLAAAGVP VEVHNAQTLV HGYVGYAGVV PAATEATNRG LVALRVVLHG
Title : Human lysosomal acid lipase inhibitor lalistat impairs Mycobacterium tuberculosis growth by targeting bacterial hydrolases - Lehmann_2016_Medchemcomm_7_1797 |
Author(s) : Lehmann J , Vomacka J , Esser K , Nodwell M , Kolbe K , Ramer P , Protzer U , Reiling N , Sieber SA |
Ref : Medchemcomm , 7 :1797 , 2016 |
Abstract : |
PubMedSearch : Lehmann_2016_Medchemcomm_7_1797 |
PubMedID: |
Gene_locus related to this paper: myctu-cutas1 , myctu-lipG , myctu-RV0045C , myctu-rv0183 , myctu-RV0293C , myctu-RV0840C , myctu-Rv1191 , myctu-RV1192 , myctu-Rv1399c , myctu-Rv1400c , myctu-Rv1426c , myctu-Rv2045c , myctu-Rv2284 , myctu-Rv2970c , myctu-Rv3084 , myctu-YR15 , larcr-a0a0f7ir14 |
Title : An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae - Philipp_1996_Proc.Natl.Acad.Sci.U.S.A_93_3132 |
Author(s) : Philipp WJ , Poulet S , Eiglmeier K , Pascopella L , Balasubramanian V , Heym B , Bergh S , Bloom BR , Jacobs WR, Jr. , Cole ST |
Ref : Proc Natl Acad Sci U S A , 93 :3132 , 1996 |
Abstract : |
PubMedSearch : Philipp_1996_Proc.Natl.Acad.Sci.U.S.A_93_3132 |
PubMedID: 8610181 |
Gene_locus related to this paper: myctu-Rv0217c , myctu-Rv0220 , myctu-Rv1076 , myctu-Rv1399c , myctu-Rv1400c , myctu-Rv1426c , myctu-Rv2045c , myctu-Rv2284 , myctu-Rv2385 , myctu-Rv2485c , myctu-Rv2970c , myctu-Rv3084 , myctu-Rv3097c , myctu-Rv3487c |