Deshpande S

References (28)

Title : Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection - Deinhardt-Emmer_2023_Aging.Dis__
Author(s) : Deinhardt-Emmer S , Deshpande S , Kitazawa K , Herman AB , Bons J , Rose JP , Kumar PA , Anerillas C , Neri F , Ciotlos S , Perez K , Kose-Vogel N , Hader A , Abdelmohsen K , Loffler B , Gorospe M , Desprez PY , Melov S , Furman D , Schilling B , Campisi J
Ref : Aging Dis , : , 2023
Abstract : During cellular senescence, persistent growth arrest and changes in protein expression programs are accompanied by a senescence-associated secretory phenotype (SASP). In this study, we detected the upregulation of the SASP-related protein dipeptidyl peptidase 4 (DDP4) in human primary lung cells rendered senescent by exposure to ionizing radiation. DPP4 is an exopeptidase that plays a crucial role in the cleavage of various proteins, resulting in the loss of N-terminal dipeptides and proinflammatory effects. Interestingly, our data revealed an association between severe coronavirus disease 2019 (COVID-19) and DDP4, namely that DPP4 levels increased in the plasma of patients with COVID-19 and were correlated with age and disease progression. Although we could not determine the direct effect of DDP4 on viral replication, mechanistic studies in cell culture revealed a negative impact on the expression of the tight junction protein zonula occludens-1 (ZO-1), which contributes to epithelial barrier function. Mass spectrometry analysis indicated that DPP4 overexpressing cells exhibited a decrease in ZO-1 and increased expression of pro-inflammatory cytokines and chemokines. By investigating the effect of DPP4 on the barrier function of human primary cells, we detected an increase in ZO-1 using DPP4 inhibitors. These results provide an important contribution to our understanding of DPP4 in the context of senescence, suggesting that DPP4 plays a major role as part of the SASP. Our results provide evidence that cellular senescence, a hallmark of aging, has an important impact on respiratory infections.
ESTHER : Deinhardt-Emmer_2023_Aging.Dis__
PubMedSearch : Deinhardt-Emmer_2023_Aging.Dis__
PubMedID: 37728586

Title : Comparative genomics of biotechnologically important yeasts - Riley_2016_Proc.Natl.Acad.Sci.U.S.A_113_9882
Author(s) : Riley R , Haridas S , Wolfe KH , Lopes MR , Hittinger CT , Goker M , Salamov AA , Wisecaver JH , Long TM , Calvey CH , Aerts AL , Barry KW , Choi C , Clum A , Coughlan AY , Deshpande S , Douglass AP , Hanson SJ , Klenk HP , LaButti KM , Lapidus A , Lindquist EA , Lipzen AM , Meier-Kolthoff JP , Ohm RA , Otillar RP , Pangilinan JL , Peng Y , Rokas A , Rosa CA , Scheuner C , Sibirny AA , Slot JC , Stielow JB , Sun H , Kurtzman CP , Blackwell M , Grigoriev IV , Jeffries TW
Ref : Proc Natl Acad Sci U S A , 113 :9882 , 2016
Abstract : Ascomycete yeasts are metabolically diverse, with great potential for biotechnology. Here, we report the comparative genome analysis of 29 taxonomically and biotechnologically important yeasts, including 16 newly sequenced. We identify a genetic code change, CUG-Ala, in Pachysolen tannophilus in the clade sister to the known CUG-Ser clade. Our well-resolved yeast phylogeny shows that some traits, such as methylotrophy, are restricted to single clades, whereas others, such as l-rhamnose utilization, have patchy phylogenetic distributions. Gene clusters, with variable organization and distribution, encode many pathways of interest. Genomics can predict some biochemical traits precisely, but the genomic basis of others, such as xylose utilization, remains unresolved. Our data also provide insight into early evolution of ascomycetes. We document the loss of H3K9me2/3 heterochromatin, the origin of ascomycete mating-type switching, and panascomycete synteny at the MAT locus. These data and analyses will facilitate the engineering of efficient biosynthetic and degradative pathways and gateways for genomic manipulation.
ESTHER : Riley_2016_Proc.Natl.Acad.Sci.U.S.A_113_9882
PubMedSearch : Riley_2016_Proc.Natl.Acad.Sci.U.S.A_113_9882
PubMedID: 27535936
Gene_locus related to this paper: wicaa-a0a1e3nx95 , cybjn-a0a1e4s739 , 9asco-a0a1q2yku6 , ogapd-w1qjr8 , 9asco-a0a1e3pdp5 , lipst-a0a1e3qdq0 , 9asco-a0a1e4tg55

Title : Pharmacokinetic characterization of BMS-936561, an anti-CD70 antibody-drug conjugate, in preclinical animal species and prediction of its pharmacokinetics in humans - Wang_2016_Biopharm.Drug.Dispos_37_93
Author(s) : Wang H , Rangan VS , Sung MC , Passmore D , Kempe T , Wang X , Thevanayagam L , Pan C , Rao C , Srinivasan M , Zhang Q , Gangwar S , Deshpande S , Cardarelli P , Marathe P , Yang Z
Ref : Biopharmaceutics & Drug Disposition , 37 :93 , 2016
Abstract : CD70 is a tumor necrosis factor (TNF)-like type II integral membrane protein that is transiently expressed on activated T- and B-lymphocytes. Aberrant expression of CD70 was identified in both solid tumors and haematologic malignancies. BMS-936561 (alphaCD70_MED-A) is an antibody-drug conjugate composed of a fully human anti-CD70 monoclonal antibody (alphaCD70) conjugated with a duocarmycin derivative, MED-A, through a maleimide-containing citrulline-valine dipeptide linker. MED-A is a carbamate prodrug that is activated by carboxylesterase to its active form, MED-B, to exert its DNA alkylation activity. In vitro serum stability studies suggested the efficiencies of hydrolyzing the carbamate-protecting group in alphaCD70_MED-A followed a rank order of mouse > rat > > monkey > dog ~ human. Pharmacokinetics of alphaCD70_MED-A was evaluated in mice, monkeys, and dogs after single intravenous doses. In mice, alphaCD70_MED-A was cleared rapidly, with no detectable exposures after 15 min following dosing. In contrast, alphaCD70_MED-A was much more stable in monkeys and dogs. The clearance of alphaCD70_MED-A in monkeys was 58 mL/d/kg, ~2-fold faster than that in dogs (31 mL/d/kg). The human PK profiles of the total alphaCD70 and alphaCD70_MED-A were predicted using allometrically scaled monkeys PK parameters of alphaCD70 and the carbamate hydrolysis rate constant estimated in dogs. Comparing the predicted and observed human PK from the phase I study, the dose-normalized concentration-time profiles of alphaCD70_MED-A and the total alphaCD70 were largely within the 5(th) -95(th) percentile of the predicted profiles. Copyright (c) 2015 John Wiley & Sons, Ltd.
ESTHER : Wang_2016_Biopharm.Drug.Dispos_37_93
PubMedSearch : Wang_2016_Biopharm.Drug.Dispos_37_93
PubMedID: 25869904

Title : Genome sequence of the thermophilic fresh-water bacterium Spirochaeta caldaria type strain (H1(T)), reclassification of Spirochaeta caldaria, Spirochaeta stenostrepta, and Spirochaeta zuelzerae in the genus Treponema as Treponema caldaria comb. nov., Treponema stenostrepta comb. nov., and Treponema zuelzerae comb. nov., and emendation of the genus Treponema - Abt_2013_Stand.Genomic.Sci_8_88
Author(s) : Abt B , Goker M , Scheuner C , Han C , Lu M , Misra M , Lapidus A , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Goodwin LA , Pitluck S , Liolios K , Pagani I , Ivanova N , Mavromatis K , Mikhailova N , Huntemann M , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Jeffries CD , Rohde M , Spring S , Gronow S , Detter JC , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Woyke T , Klenk HP
Ref : Stand Genomic Sci , 8 :88 , 2013
Abstract : Spirochaeta caldaria Pohlschroeder et al. 1995 is an obligately anaerobic, spiral-shaped bacterium that is motile via periplasmic flagella. The type strain, H1(T), was isolated in 1990 from cyanobacterial mat samples collected at a freshwater hot spring in Oregon, USA, and is of interest because it enhances the degradation of cellulose when grown in co-culture with Clostridium thermocellum. Here we provide a taxonomic re-evaluation for S. caldaria based on phylogenetic analyses of 16S rRNA sequences and whole genomes, and propose the reclassification of S. caldaria and two other Spirochaeta species as members of the emended genus Treponema. Whereas genera such as Borrelia and Sphaerochaeta possess well-distinguished genomic features related to their divergent lifestyles, the physiological and functional genomic characteristics of Spirochaeta and Treponema appear to be intermixed and are of little taxonomic value. The 3,239,340 bp long genome of strain H1(T) with its 2,869 protein-coding and 59 RNA genes is a part of the G enomic E ncyclopedia of Bacteria and Archaea project.
ESTHER : Abt_2013_Stand.Genomic.Sci_8_88
PubMedSearch : Abt_2013_Stand.Genomic.Sci_8_88
PubMedID: 23961314
Gene_locus related to this paper: trech-f8f1l1

Title : Draft genome sequence of Frankia sp. strain QA3, a nitrogen-fixing actinobacterium isolated from the root nodule of Alnus nitida - Sen_2013_Genome.Announc_1_e0010313
Author(s) : Sen A , Beauchemin N , Bruce D , Chain P , Chen A , Walston Davenport K , Deshpande S , Detter C , Furnholm T , Ghodbhane-Gtari F , Goodwin L , Gtari M , Han C , Han J , Huntemann M , Ivanova N , Kyrpides N , Land ML , Markowitz V , Mavrommatis K , Nolan M , Nouioui I , Pagani I , Pati A , Pitluck S , Santos CL , Sur S , Szeto E , Tavares F , Teshima H , Thakur S , Wall L , Woyke T , Wishart J , Tisa LS
Ref : Genome Announc , 1 :e0010313 , 2013
Abstract : Members of the actinomycete genus Frankia form a nitrogen-fixing symbiosis with 8 different families of actinorhizal plants. We report a high-quality draft genome sequence for Frankia sp. strain QA3, a nitrogen-fixing actinobacterium isolated from root nodules of Alnus nitida.
ESTHER : Sen_2013_Genome.Announc_1_e0010313
PubMedSearch : Sen_2013_Genome.Announc_1_e0010313
PubMedID: 23516220
Gene_locus related to this paper: 9acto-i8qvq8 , 9actn-i8qfl2

Title : Complete Genome of Enterobacteriaceae Bacterium Strain FGI 57, a Strain Associated with Leaf-Cutter Ant Fungus Gardens - Aylward_2013_Genome.Announc_1_E00238
Author(s) : Aylward FO , Tremmel DM , Bruce DC , Chain P , Chen A , Walston Davenport K , Detter C , Han CS , Han J , Huntemann M , Ivanova NN , Kyrpides NC , Markowitz V , Mavrommatis K , Nolan M , Pagani I , Pati A , Pitluck S , Deshpande S , Goodwin L , Woyke T , Currie CR
Ref : Genome Announc , 1 : , 2013
Abstract : The Enterobacteriaceae bacterium strain FGI 57 was isolated from a fungus garden of the leaf-cutter ant Atta colombica. Analysis of its single 4.76-Mbp chromosome will shed light on community dynamics and plant biomass degradation in ant fungus gardens.
ESTHER : Aylward_2013_Genome.Announc_1_E00238
PubMedSearch : Aylward_2013_Genome.Announc_1_E00238
PubMedID: 23469353
Gene_locus related to this paper: entbf-l0m2y4 , ecolx-e0qx45 , entbf-l0lyj5 , entbf-l0m5k3 , entbf-l0m5q3

Title : Complete genome sequence of Coriobacterium glomerans type strain (PW2(T)) from the midgut of Pyrrhocoris apterus L. (red soldier bug) - Stackebrandt_2013_Stand.Genomic.Sci_8_15
Author(s) : Stackebrandt E , Zeytun A , Lapidus A , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Goodwin LA , Pitluck S , Liolios K , Pagani I , Ivanova N , Mavromatis K , Mikhailova N , Huntemann M , Pati A , Chen A , Palaniappan K , Chang YJ , Land M , Hauser L , Rohde M , Pukall R , Goker M , Detter JC , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP
Ref : Stand Genomic Sci , 8 :15 , 2013
Abstract : Coriobacterium glomerans Haas and Konig 1988, is the only species of the genus Coriobacterium, family Coriobacteriaceae, order Coriobacteriales, phylum Actinobacteria. The bacterium thrives as an endosymbiont of pyrrhocorid bugs, i.e. the red fire bug Pyrrhocoris apterus L. The rationale for sequencing the genome of strain PW2(T) is its endosymbiotic life style which is rare among members of Actinobacteria. Here we describe the features of this symbiont, together with the complete genome sequence and its annotation. This is the first complete genome sequence of a member of the genus Coriobacterium and the sixth member of the order Coriobacteriales for which complete genome sequences are now available. The 2,115,681 bp long single replicon genome with its 1,804 protein-coding and 54 RNA genes is part of the G enomic E ncyclopedia of Bacteria and Archaea project.
ESTHER : Stackebrandt_2013_Stand.Genomic.Sci_8_15
PubMedSearch : Stackebrandt_2013_Stand.Genomic.Sci_8_15
PubMedID: 23961308
Gene_locus related to this paper: corgp-f2n8w7

Title : Complete Genome of Serratia sp. Strain FGI 94, a Strain Associated with Leaf-Cutter Ant Fungus Gardens - Aylward_2013_Genome.Announc_1_e0023912
Author(s) : Aylward FO , Tremmel DM , Starrett GJ , Bruce DC , Chain P , Chen A , Davenport KW , Detter C , Han CS , Han J , Huntemann M , Ivanova NN , Kyrpides NC , Markowitz V , Mavrommatis K , Nolan M , Pagani I , Pati A , Pitluck S , Teshima H , Deshpande S , Goodwin L , Woyke T , Currie CR
Ref : Genome Announc , 1 :e0023912 , 2013
Abstract : Serratia sp. strain FGI 94 was isolated from a fungus garden of the leaf-cutter ant Atta colombica. Analysis of its 4.86-Mbp chromosome will help advance our knowledge of symbiotic interactions and plant biomass degradation in this ancient ant-fungus mutualism.
ESTHER : Aylward_2013_Genome.Announc_1_e0023912
PubMedSearch : Aylward_2013_Genome.Announc_1_e0023912
PubMedID: 23516234
Gene_locus related to this paper: serma-l0mn97 , serma-l0mh84 , serma-l0mif0

Title : Draft genome sequence of Frankia sp. strain CN3, an atypical, noninfective (Nod-) ineffective (Fix-) isolate from Coriaria nepalensis - Ghodhbane-Gtari_2013_Genome.Announc_1_e0008513
Author(s) : Ghodhbane-Gtari F , Beauchemin N , Bruce D , Chain P , Chen A , Walston Davenport K , Deshpande S , Detter C , Furnholm T , Goodwin L , Gtari M , Han C , Han J , Huntemann M , Ivanova N , Kyrpides N , Land ML , Markowitz V , Mavrommatis K , Nolan M , Nouioui I , Pagani I , Pati A , Pitluck S , Santos CL , Sen A , Sur S , Szeto E , Tavares F , Teshima H , Thakur S , Wall L , Woyke T , Tisa LS
Ref : Genome Announc , 1 :e0008513 , 2013
Abstract : We report here the genome sequence of Frankia sp. strain CN3, which was isolated from Coriaria nepalensis. This genome sequence is the first from the fourth lineage of Frankia, strains of which are unable to reinfect actinorhizal plants. At 10 Mb, it represents the largest Frankia genome sequenced to date.
ESTHER : Ghodhbane-Gtari_2013_Genome.Announc_1_e0008513
PubMedSearch : Ghodhbane-Gtari_2013_Genome.Announc_1_e0008513
PubMedID: 23516212
Gene_locus related to this paper: 9acto-g6hh93

Title : Complete genome sequence of the halophilic bacterium Spirochaeta africana type strain (Z-7692(T)) from the alkaline Lake Magadi in the East African Rift - Liolos_2013_Stand.Genomic.Sci_8_165
Author(s) : Liolos K , Abt B , Scheuner C , Teshima H , Held B , Lapidus A , Nolan M , Lucas S , Deshpande S , Cheng JF , Tapia R , Goodwin LA , Pitluck S , Pagani I , Ivanova N , Mavromatis K , Mikhailova N , Huntemann M , Pati A , Chen A , Palaniappan K , Land M , Rohde M , Tindall BJ , Detter JC , Goker M , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Woyke T , Klenk HP , Kyrpides NC
Ref : Stand Genomic Sci , 8 :165 , 2013
Abstract : Spirochaeta africana Zhilina et al. 1996 is an anaerobic, aerotolerant, spiral-shaped bacterium that is motile via periplasmic flagella. The type strain of the species, Z-7692(T), was isolated in 1993 or earlier from a bacterial bloom in the brine under the trona layer in a shallow lagoon of the alkaline equatorial Lake Magadi in Kenya. Here we describe the features of this organism, together with the complete genome sequence, and annotation. Considering the pending reclassification of S. caldaria to the genus Treponema, S. africana is only the second 'true' member of the genus Spirochaeta with a genome-sequenced type strain to be published. The 3,285,855 bp long genome of strain Z-7692(T) with its 2,817 protein-coding and 57 RNA genes is a part of the G enomic E ncyclopedia of B acteria and A rchaea project.
ESTHER : Liolos_2013_Stand.Genomic.Sci_8_165
PubMedSearch : Liolos_2013_Stand.Genomic.Sci_8_165
PubMedID: 23991249
Gene_locus related to this paper: spiaz-h9uj53

Title : Complete genome sequence of the aerobic, heterotroph Marinithermus hydrothermalis type strain (T1(T)) from a deep-sea hydrothermal vent chimney - Copeland_2012_Stand.Genomic.Sci_6_21
Author(s) : Copeland A , Gu W , Yasawong M , Lapidus A , Lucas S , Deshpande S , Pagani I , Tapia R , Cheng JF , Goodwin LA , Pitluck S , Liolios K , Ivanova N , Mavromatis K , Mikhailova N , Pati A , Chen A , Palaniappan K , Land M , Pan C , Brambilla EM , Rohde M , Tindall BJ , Sikorski J , Goker M , Detter JC , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Woyke T
Ref : Stand Genomic Sci , 6 :21 , 2012
Abstract : Marinithermus hydrothermalis Sako et al. 2003 is the type species of the monotypic genus Marinithermus. M. hydrothermalis T1(T) was the first isolate within the phylum "Thermus-Deinococcus" to exhibit optimal growth under a salinity equivalent to that of sea water and to have an absolute requirement for NaCl for growth. M. hydrothermalis T1(T) is of interest because it may provide a new insight into the ecological significance of the aerobic, thermophilic decomposers in the circulation of organic compounds in deep-sea hydrothermal vent ecosystems. This is the first completed genome sequence of a member of the genus Marinithermus and the seventh sequence from the family Thermaceae. Here we describe the features of this organism, together with the complete genome sequence and annotation. The 2,269,167 bp long genome with its 2,251 protein-coding and 59 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Copeland_2012_Stand.Genomic.Sci_6_21
PubMedSearch : Copeland_2012_Stand.Genomic.Sci_6_21
PubMedID: 22675595
Gene_locus related to this paper: marht-f2nq80

Title : Reference genome sequence of the model plant Setaria - Bennetzen_2012_Nat.Biotechnol_30_555
Author(s) : Bennetzen JL , Schmutz J , Wang H , Percifield R , Hawkins J , Pontaroli AC , Estep M , Feng L , Vaughn JN , Grimwood J , Jenkins J , Barry K , Lindquist E , Hellsten U , Deshpande S , Wang X , Wu X , Mitros T , Triplett J , Yang X , Ye CY , Mauro-Herrera M , Wang L , Li P , Sharma M , Sharma R , Ronald PC , Panaud O , Kellogg EA , Brutnell TP , Doust AN , Tuskan GA , Rokhsar D , Devos KM
Ref : Nat Biotechnol , 30 :555 , 2012
Abstract : We generated a high-quality reference genome sequence for foxtail millet (Setaria italica). The approximately 400-Mb assembly covers approximately 80% of the genome and >95% of the gene space. The assembly was anchored to a 992-locus genetic map and was annotated by comparison with >1.3 million expressed sequence tag reads. We produced more than 580 million RNA-Seq reads to facilitate expression analyses. We also sequenced Setaria viridis, the ancestral wild relative of S. italica, and identified regions of differential single-nucleotide polymorphism density, distribution of transposable elements, small RNA content, chromosomal rearrangement and segregation distortion. The genus Setaria includes natural and cultivated species that demonstrate a wide capacity for adaptation. The genetic basis of this adaptation was investigated by comparing five sequenced grass genomes. We also used the diploid Setaria genome to evaluate the ongoing genome assembly of a related polyploid, switchgrass (Panicum virgatum).
ESTHER : Bennetzen_2012_Nat.Biotechnol_30_555
PubMedSearch : Bennetzen_2012_Nat.Biotechnol_30_555
PubMedID: 22580951
Gene_locus related to this paper: setit-k3xwe0 , setit-k3xfs7 , setit-k3yh36 , setit-k3zes3 , setit-k3zlj8 , setvi-a0a4u6wd58 , setit-a0a368qif6 , setit-a0a368sru6 , setit-a0a368q9x4 , setit-k3zri0 , setit-k3ysv0 , setit-k3xj49 , setit-k4ac30

Title : Complete genome sequence of the sulfur compounds oxidizing chemolithoautotroph Sulfuricurvum kujiense type strain (YK-1(T)) - Han_2012_Stand.Genomic.Sci_6_94
Author(s) : Han C , Kotsyurbenko O , Chertkov O , Held B , Lapidus A , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Goodwin LA , Pitluck S , Liolios K , Pagani I , Ivanova N , Mavromatis K , Mikhailova N , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Brambilla EM , Rohde M , Spring S , Sikorski J , Goker M , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Detter JC
Ref : Stand Genomic Sci , 6 :94 , 2012
Abstract : Sulfuricurvum kujiense Kodama and Watanabe 2004 is the type species of the monotypic genus Sulfuricurvum, which belongs to the family Helicobacteraceae in the class Epsilonproteobacteria. The species is of interest because it is frequently found in crude oil and oil sands where it utilizes various reduced sulfur compounds such as elemental sulfur, sulfide and thiosulfate as electron donors. Members of the species do not utilize sugars, organic acids or hydrocarbons as carbon and energy sources. This genome sequence represents the type strain of the only species in the genus Sulfuricurvum. The genome, which consists of a circular chromosome of 2,574,824 bp length and four plasmids of 118,585 bp, 71,513 bp, 51,014 bp, and 3,421 bp length, respectively, harboring a total of 2,879 protein-coding and 61 RNA genes and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Han_2012_Stand.Genomic.Sci_6_94
PubMedSearch : Han_2012_Stand.Genomic.Sci_6_94
PubMedID: 22675602
Gene_locus related to this paper: sulky-e4u307

Title : Complete genome sequence of Bacteroides helcogenes type strain (P 36-108) - Pati_2011_Stand.Genomic.Sci_4_45
Author(s) : Pati A , Gronow S , Zeytun A , Lapidus A , Nolan M , Hammon N , Deshpande S , Cheng JF , Tapia R , Han C , Goodwin L , Pitluck S , Liolios K , Pagani I , Ivanova N , Mavromatis K , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Detter JC , Brambilla E , Rohde M , Goker M , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Lucas S
Ref : Stand Genomic Sci , 4 :45 , 2011
Abstract : Bacteroides helcogenes Benno et al. 1983 is of interest because of its isolated phylogenetic location and, although it has been found in pig feces and is known to be pathogenic for pigs, occurrence of this bacterium is rare and it does not cause significant damage in intensive animal husbandry. The genome of B. helcogenes P 36-108(T) is already the fifth completed and published type strain genome from the genus Bacteroides in the family Bacteroidaceae. The 3,998,906 bp long genome with its 3,353 protein-coding and 83 RNA genes consists of one circular chromosome and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Pati_2011_Stand.Genomic.Sci_4_45
PubMedSearch : Pati_2011_Stand.Genomic.Sci_4_45
PubMedID: 21475586
Gene_locus related to this paper: bact6-e6sny5 , bact6-e6sqv4 , bact6-e6str2 , bact6-e6suh8 , bact6-e6suk4 , bact6-e6sn75

Title : Complete genome sequence of Desulfobulbus propionicus type strain (1pr3) - Pagani_2011_Stand.Genomic.Sci_4_100
Author(s) : Pagani I , Lapidus A , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Chertkov O , Davenport K , Tapia R , Han C , Goodwin L , Pitluck S , Liolios K , Mavromatis K , Ivanova N , Mikhailova N , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Detter JC , Brambilla E , Kannan KP , Djao OD , Rohde M , Pukall R , Spring S , Goker M , Sikorski J , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP
Ref : Stand Genomic Sci , 4 :100 , 2011
Abstract : Desulfobulbus propionicus Widdel 1981 is the type species of the genus Desulfobulbus, which belongs to the family Desulfobulbaceae. The species is of interest because of its great implication in the sulfur cycle in aquatic sediments, its large substrate spectrum and a broad versatility in using various fermentation pathways. The species was the first example of a pure culture known to disproportionate elemental sulfur to sulfate and sulfide. This is the first completed genome sequence of a member of the genus Desulfobulbus and the third published genome sequence from a member of the family Desulfobulbaceae. The 3,851,869 bp long genome with its 3,351 protein-coding and 57 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Pagani_2011_Stand.Genomic.Sci_4_100
PubMedSearch : Pagani_2011_Stand.Genomic.Sci_4_100
PubMedID: 21475592
Gene_locus related to this paper: despd-e8rdj0 , despd-e8rjl1

Title : Complete genome sequence of Cellulophaga algicola type strain (IC166) - Abt_2011_Stand.Genomic.Sci_4_72
Author(s) : Abt B , Lu M , Misra M , Han C , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Goodwin L , Pitluck S , Liolios K , Pagani I , Ivanova N , Mavromatis K , Ovchinikova G , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Detter JC , Brambilla E , Rohde M , Tindall BJ , Goker M , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Lapidus A
Ref : Stand Genomic Sci , 4 :72 , 2011
Abstract : Cellulophaga algicola Bowman 2000 belongs to the family Flavobacteriaceae within the phylum 'Bacteroidetes' and was isolated from Melosira collected from the Eastern Antarctic coastal zone. The species is of interest because its members produce a wide range of extracellular enzymes capable of degrading proteins and polysaccharides with temperature optima of 20-30 degrees C. This is the first completed genome sequence of a member of the genus Cellulophaga. The 4,888,353 bp long genome with its 4,285 protein-coding and 62 RNA genes consists of one circular chromosome and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Abt_2011_Stand.Genomic.Sci_4_72
PubMedSearch : Abt_2011_Stand.Genomic.Sci_4_72
PubMedID: 21475589
Gene_locus related to this paper: celad-e6x4e5 , celad-e6x420 , celad-e6x777 , celad-e6xbe7

Title : Complete genome sequence of Cellulophaga lytica type strain (LIM-21) - Pati_2011_Stand.Genomic.Sci_4_221
Author(s) : Pati A , Abt B , Teshima H , Nolan M , Lapidus A , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Han C , Goodwin L , Pitluck S , Liolios K , Pagani I , Mavromatis K , Ovchinikova G , Chen A , Palaniappan K , Land M , Hauser L , Jeffries CD , Detter JC , Brambilla EM , Kannan KP , Rohde M , Spring S , Goker M , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Ivanova N
Ref : Stand Genomic Sci , 4 :221 , 2011
Abstract : Cellulophaga lytica (Lewin 1969) Johansen et al. 1999 is the type species of the genus Cellulophaga, which belongs to the family Flavobacteriaceae within the phylum 'Bacteroidetes' and was isolated from marine beach mud in Limon, Costa Rica. The species is of biotechnological interest because its members produce a wide range of extracellular enzymes capable of degrading proteins and polysaccharides. After the genome sequence of Cellulophaga algicola this is the second completed genome sequence of a member of the genus Cellulophaga. The 3,765,936 bp long genome with its 3,303 protein-coding and 55 RNA genes consists of one circular chromosome and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Pati_2011_Stand.Genomic.Sci_4_221
PubMedSearch : Pati_2011_Stand.Genomic.Sci_4_221
PubMedID: 21677859
Gene_locus related to this paper: cellc-f0re62 , cellc-f0rek7 , cellc-f0rf75 , cellc-f0rgt2

Title : Complete genome sequence of Paludibacter propionicigenes type strain (WB4) - Gronow_2011_Stand.Genomic.Sci_4_36
Author(s) : Gronow S , Munk C , Lapidus A , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Han C , Goodwin L , Pitluck S , Liolios K , Ivanova N , Mavromatis K , Mikhailova N , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Brambilla E , Rohde M , Goker M , Detter JC , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP
Ref : Stand Genomic Sci , 4 :36 , 2011
Abstract : Paludibacter propionicigenes Ueki et al. 2006 is the type species of the genus Paludibacter, which belongs to the family Porphyromonadaceae. The species is of interest because of the position it occupies in the tree of life where it can be found in close proximity to members of the genus Dysgonomonas. This is the first completed genome sequence of a member of the genus Paludibacter and the third sequence from the family Porphyromonadaceae. The 3,685,504 bp long genome with its 3,054 protein-coding and 64 RNA genes consists of one circular chromosome and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Gronow_2011_Stand.Genomic.Sci_4_36
PubMedSearch : Gronow_2011_Stand.Genomic.Sci_4_36
PubMedID: 21475585
Gene_locus related to this paper: palpw-e4t0i0 , palpw-e4t5j4 , palpw-e4t287 , palpw-e4t2d5 , palpw-e4t2d6 , palpw-e4t5h4

Title : Complete genome sequence of Weeksella virosa type strain (9751) - Lang_2011_Stand.Genomic.Sci_4_81
Author(s) : Lang E , Teshima H , Lucas S , Lapidus A , Hammon N , Deshpande S , Nolan M , Cheng JF , Pitluck S , Liolios K , Pagani I , Mikhailova N , Ivanova N , Mavromatis K , Pati A , Tapia R , Han C , Goodwin L , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Brambilla EM , Kopitz M , Rohde M , Goker M , Tindall BJ , Detter JC , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Klenk HP , Kyrpides NC
Ref : Stand Genomic Sci , 4 :81 , 2011
Abstract : Weeksella virosa Holmes et al. 1987 is the sole member and type species of the genus Weeksella which belongs to the family Flavobacteriaceae of the phylum Bacteroidetes. Twenty-nine isolates, collected from clinical specimens provided the basis for the taxon description. While the species seems to be a saprophyte of the mucous membranes of healthy man and warm-blooded animals a causal relationship with disease has been reported in a few instances. Except for the ability to produce indole and to hydrolyze Tween and proteins such as casein and gelatin, this aerobic, non-motile, non-pigmented bacterial species is metabolically inert in most traditional biochemical tests. The 2,272,954 bp long genome with its 2,105 protein-coding and 76 RNA genes consists of one circular chromosome and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Lang_2011_Stand.Genomic.Sci_4_81
PubMedSearch : Lang_2011_Stand.Genomic.Sci_4_81
PubMedID: 21475590
Gene_locus related to this paper: weevc-f0nz59 , weevc-f0p0t6 , weevc-f0p2m6 , weevc-f0p272 , weevc-f0nzv7 , weevc-f0p2m3

Title : Complete genome sequence of Truepera radiovictrix type strain (RQ-24) - Ivanova_2011_Stand.Genomic.Sci_4_91
Author(s) : Ivanova N , Rohde C , Munk C , Nolan M , Lucas S , Del Rio TG , Tice H , Deshpande S , Cheng JF , Tapia R , Han C , Goodwin L , Pitluck S , Liolios K , Mavromatis K , Mikhailova N , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Brambilla E , Rohde M , Goker M , Tindall BJ , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Lapidus A
Ref : Stand Genomic Sci , 4 :91 , 2011
Abstract : Truepera radiovictrix Albuquerque et al. 2005 is the type species of the genus Truepera within the phylum "Deinococcus/Thermus". T. radiovictrix is of special interest not only because of its isolated phylogenetic location in the order Deinococcales, but also because of its ability to grow under multiple extreme conditions in alkaline, moderately saline, and high temperature habitats. Of particular interest is the fact that, T. radiovictrix is also remarkably resistant to ionizing radiation, a feature it shares with members of the genus Deinococcus. This is the first completed genome sequence of a member of the family Trueperaceae and the fourth type strain genome sequence from a member of the order Deinococcales. The 3,260,398 bp long genome with its 2,994 protein-coding and 52 RNA genes consists of one circular chromosome and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Ivanova_2011_Stand.Genomic.Sci_4_91
PubMedSearch : Ivanova_2011_Stand.Genomic.Sci_4_91
PubMedID: 21475591
Gene_locus related to this paper: trurr-d7cxw6

Title : Complete genome sequence of Bacteroides salanitronis type strain (BL78) - Gronow_2011_Stand.Genomic.Sci_4_191
Author(s) : Gronow S , Held B , Lucas S , Lapidus A , Del Rio TG , Nolan M , Tice H , Deshpande S , Cheng JF , Pitluck S , Liolios K , Pagani I , Ivanova N , Mavromatis K , Pati A , Tapia R , Han C , Goodwin L , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Brambilla EM , Rohde M , Goker M , Detter JC , Woyke T , Bristow J , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Eisen JA
Ref : Stand Genomic Sci , 4 :191 , 2011
Abstract : Bacteroides salanitronis Lan et al. 2006 is a species of the genus Bacteroides, which belongs to the family Bacteroidaceae. The species is of interest because it was isolated from the gut of a chicken and the growing awareness that the anaerobic microflora of the cecum is of benefit for the host and may impact poultry farming. The 4,308,663 bp long genome consists of a 4.24 Mbp chromosome and three plasmids (6 kbp, 19 kbp, 40 kbp) containing 3,737 protein-coding and 101 RNA genes and is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Gronow_2011_Stand.Genomic.Sci_4_191
PubMedSearch : Gronow_2011_Stand.Genomic.Sci_4_191
PubMedID: 21677856
Gene_locus related to this paper: bacsh-f0qz10 , bacsh-f0qz83 , bacsh-f0r0m7 , bacsh-f0r0s7 , bacsh-f0r5r9 , bacsh-f0r030 , bacsh-f0r440 , bacsh-f0r869 , bacsh-f0qzb0 , bacsh-f0r6i2

Title : Complete genome sequence of Isosphaera pallida type strain (IS1B) - Goker_2011_Stand.Genomic.Sci_4_63
Author(s) : Goker M , Cleland D , Saunders E , Lapidus A , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Han C , Goodwin L , Pitluck S , Liolios K , Pagani I , Ivanova N , Mavromatis K , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Detter JC , Beck B , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP
Ref : Stand Genomic Sci , 4 :63 , 2011
Abstract : Isosphaera pallida (ex Woronichin 1927) Giovannoni et al. 1995 is the type species of the genus Isosphaera. The species is of interest because it was the first heterotrophic bacterium known to be phototactic, and it occupies an isolated phylogenetic position within the Planctomycetaceae. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first complete genome sequence of a member of the genus Isosphaera and the third of a member of the family Planctomycetaceae. The 5,472,964 bp long chromosome and the 56,340 bp long plasmid with a total of 3,763 protein-coding and 60 RNA genes are part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Goker_2011_Stand.Genomic.Sci_4_63
PubMedSearch : Goker_2011_Stand.Genomic.Sci_4_63
PubMedID: 21475588
Gene_locus related to this paper: isopi-e8qx42 , isopi-e8qz61 , isopi-e8r2k6 , isopi-e8r4h2 , isopi-e8r5e4 , isopi-e8r123 , isopi-e8qz30

Title : Complete genome sequence of Mahella australiensis type strain (50-1 BON) - Sikorski_2011_Stand.Genomic.Sci_4_331
Author(s) : Sikorski J , Teshima H , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Pitluck S , Liolios K , Pagani I , Ivanova N , Huntemann M , Mavromatis K , Ovchinikova G , Pati A , Tapia R , Han C , Goodwin L , Chen A , Palaniappan K , Land M , Hauser L , Ngatchou-Djao OD , Rohde M , Pukall R , Spring S , Abt B , Goker M , Detter JC , Woyke T , Bristow J , Markowitz V , Hugenholtz P , Eisen JA , Kyrpides NC , Klenk HP , Lapidus A
Ref : Stand Genomic Sci , 4 :331 , 2011
Abstract : Mahella australiensis Bonilla Salinas et al. 2004 is the type species of the genus Mahella, which belongs to the family Thermoanaerobacteraceae. The species is of interest because it differs from other known anaerobic spore-forming bacteria in its G+C content, and in certain phenotypic traits, such as carbon source utilization and relationship to temperature. Moreover, it has been discussed that this species might be an indigenous member of petroleum and oil reservoirs. This is the first completed genome sequence of a member of the genus Mahella and the ninth completed type strain genome sequence from the family Thermoanaerobacteraceae. The 3,135,972 bp long genome with its 2,974 protein-coding and 59 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Sikorski_2011_Stand.Genomic.Sci_4_331
PubMedSearch : Sikorski_2011_Stand.Genomic.Sci_4_331
PubMedID: 21886860
Gene_locus related to this paper: maha5-f3zvv5

Title : The Medicago genome provides insight into the evolution of rhizobial symbioses - Young_2011_Nature_480_520
Author(s) : Young ND , Debelle F , Oldroyd GE , Geurts R , Cannon SB , Udvardi MK , Benedito VA , Mayer KF , Gouzy J , Schoof H , Van de Peer Y , Proost S , Cook DR , Meyers BC , Spannagl M , Cheung F , De Mita S , Krishnakumar V , Gundlach H , Zhou S , Mudge J , Bharti AK , Murray JD , Naoumkina MA , Rosen B , Silverstein KA , Tang H , Rombauts S , Zhao PX , Zhou P , Barbe V , Bardou P , Bechner M , Bellec A , Berger A , Berges H , Bidwell S , Bisseling T , Choisne N , Couloux A , Denny R , Deshpande S , Dai X , Doyle JJ , Dudez AM , Farmer AD , Fouteau S , Franken C , Gibelin C , Gish J , Goldstein S , Gonzalez AJ , Green PJ , Hallab A , Hartog M , Hua A , Humphray SJ , Jeong DH , Jing Y , Jocker A , Kenton SM , Kim DJ , Klee K , Lai H , Lang C , Lin S , Macmil SL , Magdelenat G , Matthews L , McCorrison J , Monaghan EL , Mun JH , Najar FZ , Nicholson C , Noirot C , O'Bleness M , Paule CR , Poulain J , Prion F , Qin B , Qu C , Retzel EF , Riddle C , Sallet E , Samain S , Samson N , Sanders I , Saurat O , Scarpelli C , Schiex T , Segurens B , Severin AJ , Sherrier DJ , Shi R , Sims S , Singer SR , Sinharoy S , Sterck L , Viollet A , Wang BB , Wang K , Wang M , Wang X , Warfsmann J , Weissenbach J , White DD , White JD , Wiley GB , Wincker P , Xing Y , Yang L , Yao Z , Ying F , Zhai J , Zhou L , Zuber A , Denarie J , Dixon RA , May GD , Schwartz DC , Rogers J , Quetier F , Town CD , Roe BA
Ref : Nature , 480 :520 , 2011
Abstract : Legumes (Fabaceae or Leguminosae) are unique among cultivated plants for their ability to carry out endosymbiotic nitrogen fixation with rhizobial bacteria, a process that takes place in a specialized structure known as the nodule. Legumes belong to one of the two main groups of eurosids, the Fabidae, which includes most species capable of endosymbiotic nitrogen fixation. Legumes comprise several evolutionary lineages derived from a common ancestor 60 million years ago (Myr ago). Papilionoids are the largest clade, dating nearly to the origin of legumes and containing most cultivated species. Medicago truncatula is a long-established model for the study of legume biology. Here we describe the draft sequence of the M. truncatula euchromatin based on a recently completed BAC assembly supplemented with Illumina shotgun sequence, together capturing approximately 94% of all M. truncatula genes. A whole-genome duplication (WGD) approximately 58 Myr ago had a major role in shaping the M. truncatula genome and thereby contributed to the evolution of endosymbiotic nitrogen fixation. Subsequent to the WGD, the M. truncatula genome experienced higher levels of rearrangement than two other sequenced legumes, Glycine max and Lotus japonicus. M. truncatula is a close relative of alfalfa (Medicago sativa), a widely cultivated crop with limited genomics tools and complex autotetraploid genetics. As such, the M. truncatula genome sequence provides significant opportunities to expand alfalfa's genomic toolbox.
ESTHER : Young_2011_Nature_480_520
PubMedSearch : Young_2011_Nature_480_520
PubMedID: 22089132
Gene_locus related to this paper: medtr-b7fki4 , medtr-b7fmi1 , medtr-g7itl1 , medtr-g7iu67 , medtr-g7izm0 , medtr-g7j641 , medtr-g7jtf8 , medtr-g7jtg2 , medtr-g7jtg4 , medtr-g7kem3 , medtr-g7kml3 , medtr-g7ksx5 , medtr-g7leb3 , medtr-q1s5d8 , medtr-q1s9m3 , medtr-q1t171 , medtr-g7k9e1 , medtr-g7k9e3 , medtr-g7k9e5 , medtr-g7k9e8 , medtr-g7k9e9 , medtr-g7lbp2 , medtr-g7lch3 , medtr-g7ib94 , medtr-g7ljk8 , medtr-g7i6w5 , medtr-g7kvg4 , medtr-g7iam1 , medtr-g7iam3 , medtr-g7l754 , medtr-g7jr41 , medtr-g7l4f5 , medtr-g7l755 , medtr-a0a072vyl4 , medtr-g7jwk8 , medtr-a0a072vhg0 , medtr-a0a072vrv9 , medtr-g7kmk5 , medtr-a0a072uuf6 , medtr-a0a072urp3 , medtr-g7zzc3 , medtr-g7ie19 , medtr-g7kst7 , medtr-a0a072u5k5 , medtr-a0a072v056 , medtr-scp1 , medtr-g7kyn0 , medtr-g7inw6 , medtr-g7j3q3

Title : Complete genome sequence of Calditerrivibrio nitroreducens type strain (Yu37-1) - Pitluck_2011_Stand.Genomic.Sci_4_54
Author(s) : Pitluck S , Sikorski J , Zeytun A , Lapidus A , Nolan M , Lucas S , Hammon N , Deshpande S , Cheng JF , Tapia R , Han C , Goodwin L , Liolios K , Pagani I , Ivanova N , Mavromatis K , Pati A , Chen A , Palaniappan K , Hauser L , Chang YJ , Jeffries CD , Detter JC , Brambilla E , Djao OD , Rohde M , Spring S , Goker M , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Land M
Ref : Stand Genomic Sci , 4 :54 , 2011
Abstract : Calditerrivibrio nitroreducens Iino et al. 2008 is the type species of the genus Calditerrivibrio. The species is of interest because of its important role in the nitrate cycle as nitrate reducer and for its isolated phylogenetic position in the Tree of Life. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the third complete genome sequence of a member of the family Deferribacteraceae. The 2,216,552 bp long genome with its 2,128 protein-coding and 50 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Pitluck_2011_Stand.Genomic.Sci_4_54
PubMedSearch : Pitluck_2011_Stand.Genomic.Sci_4_54
PubMedID: 21475587

Title : Complete genome sequence of Coraliomargarita akajimensis type strain (04OKA010-24) - Mavromatis_2010_Stand.Genomic.Sci_2_290
Author(s) : Mavromatis K , Abt B , Brambilla E , Lapidus A , Copeland A , Deshpande S , Nolan M , Lucas S , Tice H , Cheng JF , Han C , Detter JC , Woyke T , Goodwin L , Pitluck S , Held B , Brettin T , Tapia R , Ivanova N , Mikhailova N , Pati A , Liolios K , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Rohde M , Goker M , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Klenk HP , Kyrpides NC
Ref : Stand Genomic Sci , 2 :290 , 2010
Abstract : Coraliomargarita akajimensis Yoon et al. 2007 is the type species of the genus Coraliomargarita. C. akajimensis is an obligately aerobic, Gram-negative, non-spore-forming, non-motile, spherical bacterium that was isolated from seawater surrounding the hard coral Galaxea fascicularis. C. akajimensis is of special interest because of its phylogenetic position in a genomically under-studied area of the bacterial diversity. Here we describe the features of this organism, together with the complete genome sequence, and annotation. This is the first complete genome sequence of a member of the family Puniceicoccaceae. The 3,750,771 bp long genome with its 3,137 protein-coding and 55 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Mavromatis_2010_Stand.Genomic.Sci_2_290
PubMedSearch : Mavromatis_2010_Stand.Genomic.Sci_2_290
PubMedID: 21304713
Gene_locus related to this paper: corad-d5ehl2 , corad-d5ene2 , corad-d5epb6 , corad-d5epc2 , corad-d5epz5

Title : Complete genome sequence of Intrasporangium calvum type strain (7 KIP) - Del Rio_2010_Stand.Genomic.Sci_3_294
Author(s) : Del Rio TG , Chertkov O , Yasawong M , Lucas S , Deshpande S , Cheng JF , Detter C , Tapia R , Han C , Goodwin L , Pitluck S , Liolios K , Ivanova N , Mavromatis K , Pati A , Chen A , Palaniappan K , Land M , Hauser L , Chang YJ , Jeffries CD , Rohde M , Pukall R , Sikorski J , Goker M , Woyke T , Bristow J , Eisen JA , Markowitz V , Hugenholtz P , Kyrpides NC , Klenk HP , Lapidus A
Ref : Stand Genomic Sci , 3 :294 , 2010
Abstract : Intrasporangium calvum Kalakoutskii et al. 1967 is the type species of the genus Intrasporangium, which belongs to the actinobacterial family Intrasporangiaceae. The species is a Gram-positive bacterium that forms a branching mycelium, which tends to break into irregular fragments. The mycelium of this strain may bear intercalary vesicles but does not contain spores. The strain described in this study is an airborne organism that was isolated from a school dining room in 1967. One particularly interesting feature of I. calvum is that the type of its menaquinone is different from all other representatives of the family Intrasporangiaceae. This is the first completed genome sequence from a member of the genus Intrasporangium and also the first sequence from the family Intrasporangiaceae. The 4,024,382 bp long genome with its 3,653 protein-coding and 57 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.
ESTHER : Del Rio_2010_Stand.Genomic.Sci_3_294
PubMedSearch : Del Rio_2010_Stand.Genomic.Sci_3_294
PubMedID: 21304734
Gene_locus related to this paper: intc7-e6s7p7 , intc7-e6s9d8 , intc7-e6sds3 , intc7-e6s7a1 , intc7-e6sc55

Title : The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase - Wilkinson_1989_Science_246_670
Author(s) : Wilkinson KD , Lee KM , Deshpande S , Duerksen-Hughes P , Boss JM , Pohl J
Ref : Science , 246 :670 , 1989
Abstract : A complementary DNA (cDNA) for ubiquitin carboxyl-terminal hydrolase isozyme L3 was cloned from human B cells. The cDNA encodes a protein of 230 amino acids with a molecular mass of 26.182 daltons. The human protein is very similar to the bovine homolog, with only three amino acids differing in over 100 residues compared. The amino acid sequence deduced from the cDNA was 54% identical to that of the neuron-specific protein PGP 9.5. Purification of bovine PGP 9.5 confirmed that it is also a ubiquitin carboxyl-terminal hydrolase. These results suggest that a family of such related proteins exists and that their expression is tissue-specific.
ESTHER : Wilkinson_1989_Science_246_670
PubMedSearch : Wilkinson_1989_Science_246_670
PubMedID: 2530630