Ketone

General

Ketone are compound with the structure RC(=O)R', where R and R' can be a variety of carbon-containing substituents. Building block for many inhibitors of enzymes

Inhibitor	Main targeted enzyme familyes	Type
Phenylacetone	Monoglyceridelipase_lysophospholip ACHE	Ketone
Tosyl-L-lysine-chloromethyl-ketone	Carb_B_Bacteria BCHE S9N_PREPL_Peptidase_S9	Ketone Peptide Sulfur Compound Sulfonamide Benzenesulfonamide
Difluoromethyl-ketone-BT7	ACHE	Ketone Pyrazole
1,3,4-oxadiazolyl-ketone-18h	DPP4N_Peptidase_S9	Pyrrolidine Ketone Oxadiazol tert-Butyl
Lilly-aryl-ketone	DPP4N_Peptidase_S9	Ketone
2-Tridecanone	Hydroxynitrile_lyase	Natural Ketone
6AX1-cp3	Monoglyceridelipase_lysophospholip	Halo ketone Trifluoro Carbamate Azetidin Oxadiazol
Acetone	Hydroxynitrile_lyase	Ketone
Hexafluoracetone	Hydroxynitrile_lyase	Trifluoro Halo ketone
OTFP	Juvenile_hormone_esterase Cutinase	Trifluoro Halo ketone Sulfur Compound
DETFP	Juvenile_hormone_esterase Carb_B_Chordata Carboxylesterase	Trifluoro Sulfur Compound Halo ketone
OTFPdOHSO2	Juvenile_hormone_esterase	Trifluoro Sulfur Compound Sulfonyl Halo ketone
Z-Gly-Gly-Phe-chloromethyl-ketone	ACPH_Peptidase_S9	Benzyloxycarbonyl Carbamate Peptide Ketone Carboxamide
PHK	Proline_iminopeptidase	Peptide Halo ketone
JW651	Monoglyceridelipase_lysophospholip Plasmodium_subtelomeric_PST-A	Piperazine Halo ketone Carbamate Trifluoro
KML29	Monoglyceridelipase_lysophospholip Plasmodium_subtelomeric_PST-A	Halo ketone Piperidine Benzodioxo Carbamate Trifluoro
Zifrosilone	ACHE	Halo ketone Transition state analogue Trifluoro
1-Chloro-3-phenoxy-2-propanone	ACHE	Halo ketone Ketone Transition state analogue
1-phenoxypropanone	ACHE	Ketone Transition state analogue
6-Dimethyl-3-difluoro-2-heptanone	ACHE	Halo ketone Transition state analogue Analogue of substrate
6-Methyl-2-heptanone		Ketone
Coumarinyl-ethyl-p-trifluoroacetamidophenylmethylphosphonate	BCHE	Trifluoro Organophosphate Halo ketone Coumarin Chromen
TBTFA	ACHE BCHE	Halo ketone Transition state analogue Trifluoro tert-Butyl
MBTFP	Cutinase Juvenile_hormone_esterase	Trifluoro Transition state analogue Halo ketone Sulfur Compound
TMTFA	ACHE	Trifluoro Trimethylammonium Quaternary compound Transition state analogue Halo ketone
Trifluoro-6-dimethyl-2-heptanone	BCHE ACHE	Trifluoro Halo ketone