drome-CG12108

Drosophila melanogaster (Fruit fly) cg12108 protein re03479p PPT1

Comment

Relationship

Family : Palmitoyl-protein_thioesterase

Block : X

Position in NCBI Life Tree : Drosophila melanogaster

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MISICCSRFS CILFLLFLIF SLVLSYIWWS PTKGGTNPEV LPVVLWHGMG DTCCVPFSLG AIMNLIVEQT KGGYVRSLQI GGNVLIDWQS GFFIHPNEQV DYVCKQLLQD EHLAKGYHAI GFSQGGQFLR AVAERCPNPP MRNLITLGGQ HQGIFGLPMC PTLTEKPCDY ITRLLDNAAY APEVQKALVQ ATYWHDPIME NKYRLGSTFL ADINNELFIN KFYIENLQKL KKFVMVQFLN DTIVQPKESQ WFQYYTTGQN KVIQPFTESK VYQDWDWTRC IDKDNLSFSA SKVITWPYPR PGLSRT

References (12)

Title : Genetic studies in Drosophila and humans support a model for the concerted function of CISD2, PPT1 and CLN3 in disease - Jones_2014_Biol.Open_3_342
Author(s) : Jones MA , Amr S , Ferebee A , Huynh P , Rosenfeld JA , Miles MF , Davies AG , Korey CA , Warrick JM , Shiang R , Elsea SH , Girirajan S , Grotewiel M
Ref : Biol Open , 3 :342 , 2014
PubMedID: 24705017
Gene_locus related to this paper: drome-CG12108

Title : Mutations in palmitoyl-protein thioesterase 1 alter exocytosis and endocytosis at synapses in Drosophila larvae - Aby_2013_Fly.(Austin)_7_267
Author(s) : Aby E , Gumps K , Roth A , Sigmon S , Jenkins SE , Kim JJ , Kramer NJ , Parfitt KD , Korey CA
Ref : Fly (Austin) , 7 :267 , 2013
PubMedID: 24091420
Gene_locus related to this paper: drome-CG12108

Title : The Batten disease Palmitoyl Protein Thioesterase 1 gene regulates neural specification and axon connectivity during Drosophila embryonic development - Chu-LaGraff_2010_PLoS.One_5_e14402
Author(s) : Chu-LaGraff Q , Blanchette C , O'Hern P , Denefrio C
Ref : PLoS ONE , 5 :e14402 , 2010
PubMedID: 21203506
Gene_locus related to this paper: drome-CG12108

Title : Identifying cellular pathways modulated by Drosophila palmitoyl-protein thioesterase 1 function - Saja_2010_Neurobiol.Dis_40_135
Author(s) : Saja S , Buff H , Smith AC , Williams TS , Korey CA
Ref : Neurobiol Dis , 40 :135 , 2010
PubMedID: 20206262
Gene_locus related to this paper: drome-CG12108

Title : The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases - Bannan_2008_Fly.(Austin)_2_198
Author(s) : Bannan BA , Van Etten J , Kohler JA , Tsoi Y , Hansen NM , Sigmon S , Fowler E , Buff H , Williams TS , Ault JG , Glaser RL , Korey CA
Ref : Fly (Austin) , 2 :198 , 2008
PubMedID: 18719403
Gene_locus related to this paper: drome-CG4851 , drome-CG12108 , drome-CG18815

Title : Genetic modifiers of Drosophila palmitoyl-protein thioesterase 1-induced degeneration - Buff_2007_Genetics_176_209
Author(s) : Buff H , Smith AC , Korey CA
Ref : Genetics , 176 :209 , 2007
PubMedID: 17409080
Gene_locus related to this paper: drome-CG12108

Title : Palmitoyl-protein thioesterase 1 deficiency in Drosophila melanogaster causes accumulation of abnormal storage material and reduced life span - Hickey_2006_Genetics_172_2379
Author(s) : Hickey AJ , Chotkowski HL , Singh N , Ault JG , Korey CA , MacDonald ME , Glaser RL
Ref : Genetics , 172 :2379 , 2006
PubMedID: 16452138
Gene_locus related to this paper: drome-CG12108

Title : Characterizing pathogenic processes in Batten disease: use of small eukaryotic model systems - Phillips_2006_Biochim.Biophys.Acta_1762_906
Author(s) : Phillips SN , Muzaffar N , Codlin S , Korey CA , Taschner PE , de Voer G , Mole SE , Pearce DA
Ref : Biochimica & Biophysica Acta , 1762 :906 , 2006
PubMedID: 17049819
Gene_locus related to this paper: caeel-F44C4.5 , drome-CG12108

Title : Characterization of Drosophila palmitoyl-protein thioesterase 1 - Glaser_2003_Gene_312_271
Author(s) : Glaser RL , Hickey AJ , Chotkowski HL , Chu-LaGraff Q
Ref : Gene , 312 :271 , 2003
PubMedID: 12909364
Gene_locus related to this paper: drome-CG12108

Title : An over-expression system for characterizing Ppt1 function in Drosophila - Korey_2003_BMC.Neurosci_4_30
Author(s) : Korey CA , MacDonald ME
Ref : BMC Neurosci , 4 :30 , 2003
PubMedID: 14629778
Gene_locus related to this paper: drome-CG12108

Title : The genome sequence of Drosophila melanogaster - Adams_2000_Science_287_2185
Author(s) : Adams MD , Celniker SE , Holt RA , Evans CA , Gocayne JD , Amanatides PG , Scherer SE , Li PW , Hoskins RA , Galle RF , George RA , Lewis SE , Richards S , Ashburner M , Henderson SN , Sutton GG , Wortman JR , Yandell MD , Zhang Q , Chen LX , Brandon RC , Rogers YH , Blazej RG , Champe M , Pfeiffer BD , Wan KH , Doyle C , Baxter EG , Helt G , Nelson CR , Gabor GL , Abril JF , Agbayani A , An HJ , Andrews-Pfannkoch C , Baldwin D , Ballew RM , Basu A , Baxendale J , Bayraktaroglu L , Beasley EM , Beeson KY , Benos PV , Berman BP , Bhandari D , Bolshakov S , Borkova D , Botchan MR , Bouck J , Brokstein P , Brottier P , Burtis KC , Busam DA , Butler H , Cadieu E , Center A , Chandra I , Cherry JM , Cawley S , Dahlke C , Davenport LB , Davies P , de Pablos B , Delcher A , Deng Z , Mays AD , Dew I , Dietz SM , Dodson K , Doup LE , Downes M , Dugan-Rocha S , Dunkov BC , Dunn P , Durbin KJ , Evangelista CC , Ferraz C , Ferriera S , Fleischmann W , Fosler C , Gabrielian AE , Garg NS , Gelbart WM , Glasser K , Glodek A , Gong F , Gorrell JH , Gu Z , Guan P , Harris M , Harris NL , Harvey D , Heiman TJ , Hernandez JR , Houck J , Hostin D , Houston KA , Howland TJ , Wei MH , Ibegwam C , Jalali M , Kalush F , Karpen GH , Ke Z , Kennison JA , Ketchum KA , Kimmel BE , Kodira CD , Kraft C , Kravitz S , Kulp D , Lai Z , Lasko P , Lei Y , Levitsky AA , Li J , Li Z , Liang Y , Lin X , Liu X , Mattei B , McIntosh TC , McLeod MP , McPherson D , Merkulov G , Milshina NV , Mobarry C , Morris J , Moshrefi A , Mount SM , Moy M , Murphy B , Murphy L , Muzny DM , Nelson DL , Nelson DR , Nelson KA , Nixon K , Nusskern DR , Pacleb JM , Palazzolo M , Pittman GS , Pan S , Pollard J , Puri V , Reese MG , Reinert K , Remington K , Saunders RD , Scheeler F , Shen H , Shue BC , Siden-Kiamos I , Simpson M , Skupski MP , Smith T , Spier E , Spradling AC , Stapleton M , Strong R , Sun E , Svirskas R , Tector C , Turner R , Venter E , Wang AH , Wang X , Wang ZY , Wassarman DA , Weinstock GM , Weissenbach J , Williams SM , WoodageT , Worley KC , Wu D , Yang S , Yao QA , Ye J , Yeh RF , Zaveri JS , Zhan M , Zhang G , Zhao Q , Zheng L , Zheng XH , Zhong FN , Zhong W , Zhou X , Zhu S , Zhu X , Smith HO , Gibbs RA , Myers EW , Rubin GM , Venter JC
Ref : Science , 287 :2185 , 2000
PubMedID: 10731132
Gene_locus related to this paper: drome-1vite , drome-2vite , drome-3vite , drome-a1z6g9 , drome-abhd2 , drome-ACHE , drome-b6idz4 , drome-BEM46 , drome-CG5707 , drome-CG5704 , drome-CG1309 , drome-CG1882 , drome-CG1986 , drome-CG2059 , drome-CG2493 , drome-CG2528 , drome-CG2772 , drome-CG3160 , drome-CG3344 , drome-CG3523 , drome-CG3524 , drome-CG3734 , drome-CG3739 , drome-CG3744 , drome-CG3841 , drome-CG4267 , drome-CG4382 , drome-CG4390 , drome-CG4572 , drome-CG4582 , drome-CG4851 , drome-CG4979 , drome-CG5068 , drome-CG5162 , drome-CG5355 , drome-CG5377 , drome-CG5397 , drome-CG5412 , drome-CG5665 , drome-CG5932 , drome-CG5966 , drome-CG6018 , drome-CG6113 , drome-CG6271 , drome-CG6283 , drome-CG6295 , drome-CG6296 , drome-CG6414 , drome-CG6431 , drome-CG6472 , drome-CG6567 , drome-CG6675 , drome-CG6753 , drome-CG6847 , drome-CG7329 , drome-CG7367 , drome-CG7529 , drome-CG7632 , drome-CG8058 , drome-CG8093 , drome-CG8233 , drome-CG8424 , drome-CG8425 , drome-CG9059 , drome-CG9186 , drome-CG9287 , drome-CG9289 , drome-CG9542 , drome-CG9858 , drome-CG9953 , drome-CG9966 , drome-CG10116 , drome-CG10163 , drome-CG10175 , drome-CG10339 , drome-CG10357 , drome-CG10982 , drome-CG11034 , drome-CG11055 , drome-CG11309 , drome-CG11319 , drome-CG11406 , drome-CG11598 , drome-CG11600 , drome-CG11608 , drome-CG11626 , drome-CG11935 , drome-CG12108 , drome-CG12869 , drome-CG13282 , drome-CG13562 , drome-CG13772 , drome-CG14034 , drome-nlg3 , drome-CG14717 , drome-CG15101 , drome-CG15102 , drome-CG15106 , drome-CG15111 , drome-CG15820 , drome-CG15821 , drome-CG15879 , drome-CG17097 , drome-CG17099 , drome-CG17101 , drome-CG17191 , drome-CG17192 , drome-CG17292 , drome-CG18258 , drome-CG18284 , drome-CG18301 , drome-CG18302 , drome-CG18493 , drome-CG18530 , drome-CG18641 , drome-CG18815 , drome-CG31089 , drome-CG31091 , drome-CG32333 , drome-CG32483 , drome-CG33174 , drome-dnlg1 , drome-este4 , drome-este6 , drome-GH02384 , drome-GH02439 , drome-glita , drome-KRAKEN , drome-lip1 , drome-LIP2 , drome-lip3 , drome-MESK2 , drome-nrtac , drome-OME , drome-q7k274 , drome-Q9VJN0 , drome-Q8IP31 , drome-q9vux3