drome-CG8424

Drosophila melanogaster (Fruit fly) CG8424 gene for a carboxylesterase duplicated gene of juvenile hormone esterase

Comment

Nucleotide sequence from Celera || Annotation from Dr Peter Campbell : CG8425 DmJHEdup appears to be a duplication of CG8424. CG8424 is a juvenile hormone esterase. DmJHE is the hormone esterase with precise regulation and highly specific activity for its substrate, juvenile hormone. DmJHEdup is an odorant degrading esterase (ODE) responsible for processing various kairomones in antennae

Relationship

Family : Juvenile_hormone_esterase

Block : C

Position in NCBI Life Tree : Drosophila melanogaster

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MLFAGFGVLL FVAVAVGDSL DVCLEDMGCM RGTLMPGYQS GEFEAFMGIP FAQPPVGPLR LKNPVPNEPW EGVLDAGAAK DSCIQRSYFA KEWGLMGVED CLYLNVYRPK NRAEDKLPVM VYIHGGGFFS GSAHPMASGP EYLMDTNKVV MVTMNYRLGP FGFLSTGDEH MPGNFGFKDQ RLALQWIQKH IATFGGDPKK VTVLGHSAGG ISAHLHMISP NSKGLFQNSM SLTGTMFLSA MKILKDPLSQ ARRLGKELAI DQAESLSSQD LAEALRNVCP KKLLVSVDSL KVWDNMPHLT TLPVLEAPSP DAFLVEDPLD AHRAGRINQM PWILSLSSRA GEGSLFIMRA FINPKLRAEF NENFLEHMAL LLNLPEGTPV QMVSEILDAY DFKGDSLNND TMLKLAEISG DFNFYYPIYE TISSYVTYAN LEENPLFIYI FEFAGLNSIT KFFAGTTDDY GLGAVHMDDG LHTIRIPVSF DDFPKDSEDA KVIQRMSSLM TDFAKTGVFH EESICKVSDF KEQGMCNYLH FGGNKEKYLE DIRNSITLTA FPIWKKLFA

References (8)

Title : The molecular basis for the neofunctionalization of the juvenile hormone esterase duplication in Drosophila - Hopkins_2019_Insect.Biochem.Mol.Biol_106_10
Author(s) : Hopkins DH , Rane RV , Younus F , Coppin CW , Pandey G , Jackson CJ , Oakeshott JG
Ref : Insect Biochemistry & Molecular Biology , 106 :10 , 2019
PubMedID: 30611903
Gene_locus related to this paper: drome-CG8424 , drome-CG8425

Title : Neofunctionalization of Juvenile Hormone Esterase Duplication in Drosophila as an odorant-degrading enzyme towards food odorants - Steiner_2017_Sci.Rep_7_12629
Author(s) : Steiner C , Bozzolan F , Montagne N , Maibeche M , Chertemps T
Ref : Sci Rep , 7 :12629 , 2017
PubMedID: 28974761
Gene_locus related to this paper: drome-CG8424

Title : Identification of candidate odorant degrading gene\/enzyme systems in the antennal transcriptome of Drosophila melanogaster - Younus_2014_Insect.Biochem.Mol.Biol_53_30
Author(s) : Younus F , Chertemps T , Pearce SL , Pandey G , Bozzolan F , Coppin CW , Russell RJ , Maibeche-Coisne M , Oakeshott JG
Ref : Insect Biochemistry & Molecular Biology , 53 :30 , 2014
PubMedID: 25038463
Gene_locus related to this paper: drome-CG8424

Title : Jhe in Gryllus assimilis: cloning, sequence-activity associations and phylogeny - Crone_2007_Insect.Biochem.Mol.Biol_37_1359
Author(s) : Crone EJ , Zera AJ , Anand A , Oakeshott JG , Sutherland TD , Russell RJ , Harshman LG , Hoffmann FG , Claudianos C
Ref : Insect Biochemistry & Molecular Biology , 37 :1359 , 2007
PubMedID: 17967354
Gene_locus related to this paper: 9orth-a5hsi6 , drome-CG8424

Title : Only one esterase of Drosophila melanogaster is likely to degrade juvenile hormone in vivo - Crone_2007_Insect.Biochem.Mol.Biol_37_540
Author(s) : Crone EJ , Sutherland TD , Campbell PM , Coppin CW , Russell RJ , Oakeshott JG
Ref : Insect Biochemistry & Molecular Biology , 37 :540 , 2007
PubMedID: 17517331
Gene_locus related to this paper: drome-CG8424

Title : Identification of a juvenile hormone esterase gene by matching its peptide mass fingerprint with a sequence from the Drosophila genome project - Campbell_2001_Insect.Biochem.Mol.Biol_31_513
Author(s) : Campbell PM , Harcourt RL , Crone EJ , Claudianos C , Hammock BD , Russell RJ , Oakeshott JG
Ref : Insect Biochemistry & Molecular Biology , 31 :513 , 2001
PubMedID: 11267890
Gene_locus related to this paper: drome-CG8424 , drome-CG8425

Title : The genome sequence of Drosophila melanogaster - Adams_2000_Science_287_2185
Author(s) : Adams MD , Celniker SE , Holt RA , Evans CA , Gocayne JD , Amanatides PG , Scherer SE , Li PW , Hoskins RA , Galle RF , George RA , Lewis SE , Richards S , Ashburner M , Henderson SN , Sutton GG , Wortman JR , Yandell MD , Zhang Q , Chen LX , Brandon RC , Rogers YH , Blazej RG , Champe M , Pfeiffer BD , Wan KH , Doyle C , Baxter EG , Helt G , Nelson CR , Gabor GL , Abril JF , Agbayani A , An HJ , Andrews-Pfannkoch C , Baldwin D , Ballew RM , Basu A , Baxendale J , Bayraktaroglu L , Beasley EM , Beeson KY , Benos PV , Berman BP , Bhandari D , Bolshakov S , Borkova D , Botchan MR , Bouck J , Brokstein P , Brottier P , Burtis KC , Busam DA , Butler H , Cadieu E , Center A , Chandra I , Cherry JM , Cawley S , Dahlke C , Davenport LB , Davies P , de Pablos B , Delcher A , Deng Z , Mays AD , Dew I , Dietz SM , Dodson K , Doup LE , Downes M , Dugan-Rocha S , Dunkov BC , Dunn P , Durbin KJ , Evangelista CC , Ferraz C , Ferriera S , Fleischmann W , Fosler C , Gabrielian AE , Garg NS , Gelbart WM , Glasser K , Glodek A , Gong F , Gorrell JH , Gu Z , Guan P , Harris M , Harris NL , Harvey D , Heiman TJ , Hernandez JR , Houck J , Hostin D , Houston KA , Howland TJ , Wei MH , Ibegwam C , Jalali M , Kalush F , Karpen GH , Ke Z , Kennison JA , Ketchum KA , Kimmel BE , Kodira CD , Kraft C , Kravitz S , Kulp D , Lai Z , Lasko P , Lei Y , Levitsky AA , Li J , Li Z , Liang Y , Lin X , Liu X , Mattei B , McIntosh TC , McLeod MP , McPherson D , Merkulov G , Milshina NV , Mobarry C , Morris J , Moshrefi A , Mount SM , Moy M , Murphy B , Murphy L , Muzny DM , Nelson DL , Nelson DR , Nelson KA , Nixon K , Nusskern DR , Pacleb JM , Palazzolo M , Pittman GS , Pan S , Pollard J , Puri V , Reese MG , Reinert K , Remington K , Saunders RD , Scheeler F , Shen H , Shue BC , Siden-Kiamos I , Simpson M , Skupski MP , Smith T , Spier E , Spradling AC , Stapleton M , Strong R , Sun E , Svirskas R , Tector C , Turner R , Venter E , Wang AH , Wang X , Wang ZY , Wassarman DA , Weinstock GM , Weissenbach J , Williams SM , WoodageT , Worley KC , Wu D , Yang S , Yao QA , Ye J , Yeh RF , Zaveri JS , Zhan M , Zhang G , Zhao Q , Zheng L , Zheng XH , Zhong FN , Zhong W , Zhou X , Zhu S , Zhu X , Smith HO , Gibbs RA , Myers EW , Rubin GM , Venter JC
Ref : Science , 287 :2185 , 2000
PubMedID: 10731132
Gene_locus related to this paper: drome-1vite , drome-2vite , drome-3vite , drome-a1z6g9 , drome-abhd2 , drome-ACHE , drome-b6idz4 , drome-BEM46 , drome-CG5707 , drome-CG5704 , drome-CG1309 , drome-CG1882 , drome-CG1986 , drome-CG2059 , drome-CG2493 , drome-CG2528 , drome-CG2772 , drome-CG3160 , drome-CG3344 , drome-CG3523 , drome-CG3524 , drome-CG3734 , drome-CG3739 , drome-CG3744 , drome-CG3841 , drome-CG4267 , drome-CG4382 , drome-CG4390 , drome-CG4572 , drome-CG4582 , drome-CG4851 , drome-CG4979 , drome-CG5068 , drome-CG5162 , drome-CG5355 , drome-CG5377 , drome-CG5397 , drome-CG5412 , drome-CG5665 , drome-CG5932 , drome-CG5966 , drome-CG6018 , drome-CG6113 , drome-CG6271 , drome-CG6283 , drome-CG6295 , drome-CG6296 , drome-CG6414 , drome-CG6431 , drome-CG6472 , drome-CG6567 , drome-CG6675 , drome-CG6753 , drome-CG6847 , drome-CG7329 , drome-CG7367 , drome-CG7529 , drome-CG7632 , drome-CG8058 , drome-CG8093 , drome-CG8233 , drome-CG8424 , drome-CG8425 , drome-CG9059 , drome-CG9186 , drome-CG9287 , drome-CG9289 , drome-CG9542 , drome-CG9858 , drome-CG9953 , drome-CG9966 , drome-CG10116 , drome-CG10163 , drome-CG10175 , drome-CG10339 , drome-CG10357 , drome-CG10982 , drome-CG11034 , drome-CG11055 , drome-CG11309 , drome-CG11319 , drome-CG11406 , drome-CG11598 , drome-CG11600 , drome-CG11608 , drome-CG11626 , drome-CG11935 , drome-CG12108 , drome-CG12869 , drome-CG13282 , drome-CG13562 , drome-CG13772 , drome-CG14034 , drome-nlg3 , drome-CG14717 , drome-CG15101 , drome-CG15102 , drome-CG15106 , drome-CG15111 , drome-CG15820 , drome-CG15821 , drome-CG15879 , drome-CG17097 , drome-CG17099 , drome-CG17101 , drome-CG17191 , drome-CG17192 , drome-CG17292 , drome-CG18258 , drome-CG18284 , drome-CG18301 , drome-CG18302 , drome-CG18493 , drome-CG18530 , drome-CG18641 , drome-CG18815 , drome-CG31089 , drome-CG31091 , drome-CG32333 , drome-CG32483 , drome-CG33174 , drome-dnlg1 , drome-este4 , drome-este6 , drome-GH02384 , drome-GH02439 , drome-glita , drome-KRAKEN , drome-lip1 , drome-LIP2 , drome-lip3 , drome-MESK2 , drome-nrtac , drome-OME , drome-q7k274 , drome-Q9VJN0 , drome-Q8IP31 , drome-q9vux3