Drosophila melanogaster (Fruit fly) cg8093 Lipase Vaha
Vaha (CG8093), is synthesized in the midgut and moves to the brain where it concentrates in the insulin-producing cells in a process requiring Lipid Transfer Particle, a lipoprotein originating in the fat body. In response to dietary fat, Vaha stimulates insulin-like peptide release (ILP). Vaha functions as a diacylglycerol lipase
Family : Acidic_Lipase
Block : X
Position in NCBI Life Tree : Drosophila melanogaster
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N EMLVVQLIAVF LSLGLANALP ADTGRASSVT TVTIVRGHGY EIEEHEVQTS DGYILTMHRI PYSKNTGYDG PRPVVFLMHG LLCSSSDWVL AGPHSGLAYL LSEAGYDVWM GNARGNTYSK RHASKSPLLQ PFWNFEWHDI GIYDLPAMMD YVLYWTNVTQ LTYVGHSQGT TSFFVLNSMI PRFKSRIRSA HLLAPVAWME HMESPLATVG GPLLGQPNAF VELFGSAEFL PNTQLMNLFG ALLCSDEAIS QFMCTNTLFL LGGWNSPYIN ETLLPDIMAT TPAGCSVNQI FHYLQEYNSG YFRQFDYGST RNKKEYSSKT PPEYDVEGID VPTYLYYSDN DYFASLIDVD RLRYTMNPSA LKSAYRMPEE KWNHIDFLWG LNIKEILYDR VINDINNA
| Title : A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila - Singh_2024_Nat.Commun_15_4410 |
| Author(s) : Singh A , Abhilasha KV , Acharya KR , Liu H , Nirala NK , Parthibane V , Kunduri G , Abimannan T , Tantalla J , Zhu LJ , Acharya JK , Acharya UR |
| Ref : Nat Commun , 15 :4410 , 2024 |
| Abstract : |
| PubMedSearch : Singh_2024_Nat.Commun_15_4410 |
| PubMedID: 38782979 |
| Gene_locus related to this paper: drome-CG8093 |
| Title : Survival response to increased ceramide involves metabolic adaptation through novel regulators of glycolysis and lipolysis - Nirala_2013_PLoS.Genet_9_e1003556 |
| Author(s) : Nirala NK , Rahman M , Walls SM , Singh A , Zhu LJ , Bamba T , Fukusaki E , Srideshikan SM , Harris GL , Ip YT , Bodmer R , Acharya UR |
| Ref : PLoS Genet , 9 :e1003556 , 2013 |
| Abstract : |
| PubMedSearch : Nirala_2013_PLoS.Genet_9_e1003556 |
| PubMedID: 23818862 |
| Gene_locus related to this paper: drome-CG8093 |
| Title : Annotation of the Drosophila melanogaster euchromatic genome: a systematic review - Misra_2002_Genome.Biol_3_RESEARCH0083 |
| Author(s) : Misra S , Crosby MA , Mungall CJ , Matthews BB , Campbell KS , Hradecky P , Huang Y , Kaminker JS , Millburn GH , Prochnik SE , Smith CD , Tupy JL , Whitfied EJ , Bayraktaroglu L , Berman BP , Bettencourt BR , Celniker SE , de Grey AD , Drysdale RA , Harris NL , Richter J , Russo S , Schroeder AJ , Shu SQ , Stapleton M , Yamada C , Ashburner M , Gelbart WM , Rubin GM , Lewis SE |
| Ref : Genome Biol , 3 :RESEARCH0083 , 2002 |
| Abstract : |
| PubMedSearch : Misra_2002_Genome.Biol_3_RESEARCH0083 |
| PubMedID: 12537572 |
| Gene_locus related to this paper: drome-a1z6g9 , drome-abhd2 , drome-ACHE , drome-CG8058 , drome-CG8093 , drome-CG8233 , drome-CG8425 , drome-CG9059 , drome-CG9186 , drome-CG9542 , drome-CG10982 , drome-CG11309 , drome-CG11406 , drome-CG11598 , drome-CG17097 , drome-glita , drome-KRAKEN , drome-nrtac , drome-OME , drome-q7k274 , drome-q9vux3 |