drome-KRAKEN

Drosophila melanogaster (Fruit fly) probable serine hydrolase (EC 3.1.-.-) (kraken protein)

Comment

May have a role in detoxification and digestion during embryogenesis and larval development. Ubiquitously expressed before embryonic stage 11. At stage 11, expression is concentrated in the foregut and posterior midgut. By stage 15, in gastric caeca, pharynx, posterior spiracles and anterior edge of midgut. At the end of embryogenesis, expression is confined to gastric caeca. During third instar larvae, expressed at low levels in gastric caeca, midgut and hindgut and high level in fat body. Highest expression level in adult Malpighian tubule

Relationship

Family : SERHL

Block : X

Position in NCBI Life Tree : Drosophila melanogaster

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MGQTRVAATT AAQSPAAELS PETNGQTEEP LQLLGEDSWE EFSIAVPWGT VEAKWWGSKE RQPIIALHGW QDNCGSFDRL CPLLPADTSI LAIDLPGHGK SSHYPMGMQY FIFWDGICLI RRIVRKYNWK NVTLLGHSLG GALTFMYAAS FPTEVEKLIN IDIAGPTVRG TQRMAEGTGR ALDKFLDYET LPESKQPCYS YDEMIKLVLD AYDGSVDEPS VRVLMNRGMR HNPSKNGYLF ARDLRLKVSL LGMFTAEQTL AYARQIRCRV LNIRGIPGMK FETPQVYADV IATLRENAAK VVYVEVPGTH HLHLVTPDRV APHIIRFLKE A

References (11)

Title : The Release 5.1 annotation of Drosophila melanogaster heterochromatin - Smith_2007_Science_316_1586
Author(s) : Smith CD , Shu S , Mungall CJ , Karpen GH
Ref : Science , 316 :1586 , 2007
PubMedID: 17569856
Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac

Title : Sequence finishing and mapping of Drosophila melanogaster heterochromatin - Hoskins_2007_Science_316_1625
Author(s) : Hoskins RA , Carlson JW , Kennedy C , Acevedo D , Evans-Holm M , Frise E , Wan KH , Park S , Mendez-Lago M , Rossi F , Villasante A , Dimitri P , Karpen GH , Celniker SE
Ref : Science , 316 :1625 , 2007
PubMedID: 17569867
Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac

Title : Combined evidence annotation of transposable elements in genome sequences - Quesneville_2005_PLoS.Comput.Biol_1_166
Author(s) : Quesneville H , Bergman CM , Andrieu O , Autard D , Nouaud D , Ashburner M , Anxolabehere D
Ref : PLoS Comput Biol , 1 :166 , 2005
PubMedID: 16110336
Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac

Title : A Drosophila full-length cDNA resource - Stapleton_2002_Genome.Biol_3_RESEARCH0080
Author(s) : Stapleton M , Carlson J , Brokstein P , Yu C , Champe M , George R , Guarin H , Kronmiller B , Pacleb J , Park S , Wan K , Rubin GM , Celniker SE
Ref : Genome Biol , 3 :RESEARCH0080 , 2002
PubMedID: 12537569
Gene_locus related to this paper: drome-KRAKEN

Title : Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence - Celniker_2002_Genome.Biol_3_RESEARCH0079
Author(s) : Celniker SE , Wheeler DA , Kronmiller B , Carlson JW , Halpern A , Patel S , Adams M , Champe M , Dugan SP , Frise E , Hodgson A , George RA , Hoskins RA , Laverty T , Muzny DM , Nelson CR , Pacleb JM , Park S , Pfeiffer BD , Richards S , Sodergren EJ , Svirskas R , Tabor PE , Wan K , Stapleton M , Sutton GG , Venter C , Weinstock G , Scherer SE , Myers EW , Gibbs RA , Rubin GM
Ref : Genome Biol , 3 :RESEARCH0079 , 2002
PubMedID: 12537568
Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-CG17374 , drome-glita , drome-KRAKEN

Title : The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective - Kaminker_2002_Genome.Biol_3_RESEARCH0084
Author(s) : Kaminker JS , Bergman CM , Kronmiller B , Carlson J , Svirskas R , Patel S , Frise E , Wheeler DA , Lewis SE , Rubin GM , Ashburner M , Celniker SE
Ref : Genome Biol , 3 :RESEARCH0084 , 2002
PubMedID: 12537573
Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-glita , drome-KRAKEN

Title : Heterochromatic sequences in a Drosophila whole-genome shotgun assembly - Hoskins_2002_Genome.Biol_3_RESEARCH0085
Author(s) : Hoskins RA , Smith CD , Carlson JW , Carvalho AB , Halpern A , Kaminker JS , Kennedy C , Mungall CJ , Sullivan BA , Sutton GG , Yasuhara JC , Wakimoto BT , Myers EW , Celniker SE , Rubin GM , Karpen GH
Ref : Genome Biol , 3 :RESEARCH0085 , 2002
PubMedID: 12537574
Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-CG17097 , drome-CG17374 , drome-KRAKEN

Title : The genome sequence of Drosophila melanogaster - Adams_2000_Science_287_2185
Author(s) : Adams MD , Celniker SE , Holt RA , Evans CA , Gocayne JD , Amanatides PG , Scherer SE , Li PW , Hoskins RA , Galle RF , George RA , Lewis SE , Richards S , Ashburner M , Henderson SN , Sutton GG , Wortman JR , Yandell MD , Zhang Q , Chen LX , Brandon RC , Rogers YH , Blazej RG , Champe M , Pfeiffer BD , Wan KH , Doyle C , Baxter EG , Helt G , Nelson CR , Gabor GL , Abril JF , Agbayani A , An HJ , Andrews-Pfannkoch C , Baldwin D , Ballew RM , Basu A , Baxendale J , Bayraktaroglu L , Beasley EM , Beeson KY , Benos PV , Berman BP , Bhandari D , Bolshakov S , Borkova D , Botchan MR , Bouck J , Brokstein P , Brottier P , Burtis KC , Busam DA , Butler H , Cadieu E , Center A , Chandra I , Cherry JM , Cawley S , Dahlke C , Davenport LB , Davies P , de Pablos B , Delcher A , Deng Z , Mays AD , Dew I , Dietz SM , Dodson K , Doup LE , Downes M , Dugan-Rocha S , Dunkov BC , Dunn P , Durbin KJ , Evangelista CC , Ferraz C , Ferriera S , Fleischmann W , Fosler C , Gabrielian AE , Garg NS , Gelbart WM , Glasser K , Glodek A , Gong F , Gorrell JH , Gu Z , Guan P , Harris M , Harris NL , Harvey D , Heiman TJ , Hernandez JR , Houck J , Hostin D , Houston KA , Howland TJ , Wei MH , Ibegwam C , Jalali M , Kalush F , Karpen GH , Ke Z , Kennison JA , Ketchum KA , Kimmel BE , Kodira CD , Kraft C , Kravitz S , Kulp D , Lai Z , Lasko P , Lei Y , Levitsky AA , Li J , Li Z , Liang Y , Lin X , Liu X , Mattei B , McIntosh TC , McLeod MP , McPherson D , Merkulov G , Milshina NV , Mobarry C , Morris J , Moshrefi A , Mount SM , Moy M , Murphy B , Murphy L , Muzny DM , Nelson DL , Nelson DR , Nelson KA , Nixon K , Nusskern DR , Pacleb JM , Palazzolo M , Pittman GS , Pan S , Pollard J , Puri V , Reese MG , Reinert K , Remington K , Saunders RD , Scheeler F , Shen H , Shue BC , Siden-Kiamos I , Simpson M , Skupski MP , Smith T , Spier E , Spradling AC , Stapleton M , Strong R , Sun E , Svirskas R , Tector C , Turner R , Venter E , Wang AH , Wang X , Wang ZY , Wassarman DA , Weinstock GM , Weissenbach J , Williams SM , WoodageT , Worley KC , Wu D , Yang S , Yao QA , Ye J , Yeh RF , Zaveri JS , Zhan M , Zhang G , Zhao Q , Zheng L , Zheng XH , Zhong FN , Zhong W , Zhou X , Zhu S , Zhu X , Smith HO , Gibbs RA , Myers EW , Rubin GM , Venter JC
Ref : Science , 287 :2185 , 2000
PubMedID: 10731132
Gene_locus related to this paper: drome-1vite , drome-2vite , drome-3vite , drome-a1z6g9 , drome-abhd2 , drome-ACHE , drome-b6idz4 , drome-BEM46 , drome-CG5707 , drome-CG5704 , drome-CG1309 , drome-CG1882 , drome-CG1986 , drome-CG2059 , drome-CG2493 , drome-CG2528 , drome-CG2772 , drome-CG3160 , drome-CG3344 , drome-CG3523 , drome-CG3524 , drome-CG3734 , drome-CG3739 , drome-CG3744 , drome-CG3841 , drome-CG4267 , drome-CG4382 , drome-CG4390 , drome-CG4572 , drome-CG4582 , drome-CG4851 , drome-CG4979 , drome-CG5068 , drome-CG5162 , drome-CG5355 , drome-CG5377 , drome-CG5397 , drome-CG5412 , drome-CG5665 , drome-CG5932 , drome-CG5966 , drome-CG6018 , drome-CG6113 , drome-CG6271 , drome-CG6283 , drome-CG6295 , drome-CG6296 , drome-CG6414 , drome-CG6431 , drome-CG6472 , drome-CG6567 , drome-CG6675 , drome-CG6753 , drome-CG6847 , drome-CG7329 , drome-CG7367 , drome-CG7529 , drome-CG7632 , drome-CG8058 , drome-CG8093 , drome-CG8233 , drome-CG8424 , drome-CG8425 , drome-CG9059 , drome-CG9186 , drome-CG9287 , drome-CG9289 , drome-CG9542 , drome-CG9858 , drome-CG9953 , drome-CG9966 , drome-CG10116 , drome-CG10163 , drome-CG10175 , drome-CG10339 , drome-CG10357 , drome-CG10982 , drome-CG11034 , drome-CG11055 , drome-CG11309 , drome-CG11319 , drome-CG11406 , drome-CG11598 , drome-CG11600 , drome-CG11608 , drome-CG11626 , drome-CG11935 , drome-CG12108 , drome-CG12869 , drome-CG13282 , drome-CG13562 , drome-CG13772 , drome-CG14034 , drome-nlg3 , drome-CG14717 , drome-CG15101 , drome-CG15102 , drome-CG15106 , drome-CG15111 , drome-CG15820 , drome-CG15821 , drome-CG15879 , drome-CG17097 , drome-CG17099 , drome-CG17101 , drome-CG17191 , drome-CG17192 , drome-CG17292 , drome-CG18258 , drome-CG18284 , drome-CG18301 , drome-CG18302 , drome-CG18493 , drome-CG18530 , drome-CG18641 , drome-CG18815 , drome-CG31089 , drome-CG31091 , drome-CG32333 , drome-CG32483 , drome-CG33174 , drome-dnlg1 , drome-este4 , drome-este6 , drome-GH02384 , drome-GH02439 , drome-glita , drome-KRAKEN , drome-lip1 , drome-LIP2 , drome-lip3 , drome-MESK2 , drome-nrtac , drome-OME , drome-q7k274 , drome-Q9VJN0 , drome-Q8IP31 , drome-q9vux3

Title : Identification and characterization of kraken, a gene encoding a putative hydrolytic enzyme in Drosophila melanogaster - Edwin_1998_Gene_222_195
Author(s) : Edwin Chan HY , Harris SJ , O'Kane CJ
Ref : Gene , 222 :195 , 1998
PubMedID: 9831651
Gene_locus related to this paper: drome-KRAKEN