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drome-CG5966

Drosophila melanogaster (Fruit fly) CG5966 gene lipase Cancer-Associated Lipid Mobilizer (calm)

Comment

Nucleotide sequence from Celera || CG5966 preferentially targets TG containing C16 and C18 acyl chains

Relationship

Family : Pancreatic_lipase

Block : L

Position in NCBI Life Tree : Drosophila melanogaster

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MYVANTTGGL MLQTMLYLAN HTSRAAVNTL VDLPPAPKSD INEVKCFGVY GCFPINGPWN TVTRSINVHP QKPSEIEPHF TLHTRRALDQ PKYLDLNDPE SVQGMGMNPK GKIFLLVHGY LESGEIPWMW DMAKALLAHE PEGRASVVLI DWGGGASPPY VQAVANIRLV GAITAHVVHM LYEELRLPNL DNVHIIGHSL GAHLSGYAGY HLQHDFGLKP ARITGLDPAA PLFTDTDPIV RLDKTDAHFV DIVHTDANPL MKGGLGINMR LGHVDFFPNG GFDNPGCNKK FQDVVKKKTL FLTMQEFLGC NHIRSQQYFT ESIGSQCPFL GITCDSFESF KDTKCTSCEE PGHTCLRMGY HSQEDYQEQV DLGQLQQGDS PGVFYLWTGD SKPFCRLHYR ITVRVSGHDE STLHGGEVGI LSIQLHDALV KKAGKNERAA TEMMKFSQKA MYFEPGYEYK ALVAGRNLRE PEYATVNWEY PTNILNPLTW RILSAPRIYL EYILIEAMES SDLYLKLCPQ HEGAILTGAE NVLRSSYCKD

References (5)

Title : Hepatic ceramide synthesis links systemic inflammation to organelle dysfunction in cancer - Liu_2025_bioRxiv__2
Author(s) : Liu Y , Miao T , Wang A , Dantas E , Kim AR , Zhang Z , Sun X , Binari R , Asara JM , Hu Y , Goncalves MD , Janowitz T , Perrimon N
Ref : bioRxiv , : , 2025
Abstract :
PubMedSearch : Liu_2025_bioRxiv__2
PubMedID: 41256541
Gene_locus related to this paper: drome-CG5966 , human-LPL , mouse-lipli

Title : A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster - Kumar_2021_Biochemistry_60_1312
Author(s) : Kumar K , Mhetre A , Ratnaparkhi GS , Kamat SS
Ref : Biochemistry , 60 :1312 , 2021
Abstract :
PubMedSearch : Kumar_2021_Biochemistry_60_1312
PubMedID: 33827210
Gene_locus related to this paper: drome-1vite , drome-2vite , drome-3vite , drome-ACHE , drome-aes01 , drome-aes02 , drome-aes03 , drome-aes04 , drome-aes05 , drome-aes06 , drome-aes08 , drome-aes09 , drome-aes10 , drome-CG1882 , drome-CG2493 , drome-CG3160 , drome-CG3523 , drome-CG3524 , drome-CG4267 , drome-CG4851 , drome-CG4979 , drome-CG5355 , drome-CG5966 , drome-CG6113 , drome-CG6271 , drome-CG6283 , drome-CG6295 , drome-CG6296 , drome-CG8424 , drome-CG8425 , drome-CG9186 , drome-CG9542 , drome-CG9858 , drome-CG11034 , drome-CG11055 , drome-CG12108 , drome-CG15101 , drome-CG15102 , drome-CG15106 , drome-CG17097 , drome-CG17101 , drome-CG17192 , drome-CG17374 , drome-CG18815 , drome-dnlg1 , drome-est6p , drome-EST23aes07 , drome-este4 , drome-este6 , drome-KRAKEN , drome-OME , harsa-e2bfn3

Title : Comparative and functional genomics of lipases in holometabolous insects - Horne_2009_Insect.Biochem.Mol.Biol_39_547
Author(s) : Horne I , Haritos VS , Oakeshott JG
Ref : Insect Biochemistry & Molecular Biology , 39 :547 , 2009
Abstract :
PubMedSearch : Horne_2009_Insect.Biochem.Mol.Biol_39_547
PubMedID: 19540341
Gene_locus related to this paper: drome-CG4979 , drome-CG5966

Title : Quantitative genomics of aggressive behavior in Drosophila melanogaster - Edwards_2006_PLoS.Genet_2_e154
Author(s) : Edwards AC , Rollmann SM , Morgan TJ , Mackay TF
Ref : PLoS Genet , 2 :e154 , 2006
Abstract :
PubMedSearch : Edwards_2006_PLoS.Genet_2_e154
PubMedID: 17044737
Gene_locus related to this paper: drome-CG5966

Title : The genome sequence of Drosophila melanogaster - Adams_2000_Science_287_2185
Author(s) : Adams MD , Celniker SE , Holt RA , Evans CA , Gocayne JD , Amanatides PG , Scherer SE , Li PW , Hoskins RA , Galle RF , George RA , Lewis SE , Richards S , Ashburner M , Henderson SN , Sutton GG , Wortman JR , Yandell MD , Zhang Q , Chen LX , Brandon RC , Rogers YH , Blazej RG , Champe M , Pfeiffer BD , Wan KH , Doyle C , Baxter EG , Helt G , Nelson CR , Gabor GL , Abril JF , Agbayani A , An HJ , Andrews-Pfannkoch C , Baldwin D , Ballew RM , Basu A , Baxendale J , Bayraktaroglu L , Beasley EM , Beeson KY , Benos PV , Berman BP , Bhandari D , Bolshakov S , Borkova D , Botchan MR , Bouck J , Brokstein P , Brottier P , Burtis KC , Busam DA , Butler H , Cadieu E , Center A , Chandra I , Cherry JM , Cawley S , Dahlke C , Davenport LB , Davies P , de Pablos B , Delcher A , Deng Z , Mays AD , Dew I , Dietz SM , Dodson K , Doup LE , Downes M , Dugan-Rocha S , Dunkov BC , Dunn P , Durbin KJ , Evangelista CC , Ferraz C , Ferriera S , Fleischmann W , Fosler C , Gabrielian AE , Garg NS , Gelbart WM , Glasser K , Glodek A , Gong F , Gorrell JH , Gu Z , Guan P , Harris M , Harris NL , Harvey D , Heiman TJ , Hernandez JR , Houck J , Hostin D , Houston KA , Howland TJ , Wei MH , Ibegwam C , Jalali M , Kalush F , Karpen GH , Ke Z , Kennison JA , Ketchum KA , Kimmel BE , Kodira CD , Kraft C , Kravitz S , Kulp D , Lai Z , Lasko P , Lei Y , Levitsky AA , Li J , Li Z , Liang Y , Lin X , Liu X , Mattei B , McIntosh TC , McLeod MP , McPherson D , Merkulov G , Milshina NV , Mobarry C , Morris J , Moshrefi A , Mount SM , Moy M , Murphy B , Murphy L , Muzny DM , Nelson DL , Nelson DR , Nelson KA , Nixon K , Nusskern DR , Pacleb JM , Palazzolo M , Pittman GS , Pan S , Pollard J , Puri V , Reese MG , Reinert K , Remington K , Saunders RD , Scheeler F , Shen H , Shue BC , Siden-Kiamos I , Simpson M , Skupski MP , Smith T , Spier E , Spradling AC , Stapleton M , Strong R , Sun E , Svirskas R , Tector C , Turner R , Venter E , Wang AH , Wang X , Wang ZY , Wassarman DA , Weinstock GM , Weissenbach J , Williams SM , WoodageT , Worley KC , Wu D , Yang S , Yao QA , Ye J , Yeh RF , Zaveri JS , Zhan M , Zhang G , Zhao Q , Zheng L , Zheng XH , Zhong FN , Zhong W , Zhou X , Zhu S , Zhu X , Smith HO , Gibbs RA , Myers EW , Rubin GM , Venter JC
Ref : Science , 287 :2185 , 2000
Abstract :
PubMedSearch : Adams_2000_Science_287_2185
PubMedID: 10731132
Gene_locus related to this paper: drome-1vite , drome-2vite , drome-3vite , drome-a1z6g9 , drome-abhd2 , drome-ACHE , drome-b6idz4 , drome-BEM46 , drome-CG5707 , drome-CG5704 , drome-CG1309 , drome-CG1882 , drome-CG1986 , drome-CG2059 , drome-CG2493 , drome-CG2528 , drome-CG2772 , drome-CG3160 , drome-CG3344 , drome-CG3523 , drome-CG3524 , drome-CG3734 , drome-CG3739 , drome-CG3744 , drome-CG3841 , drome-CG4267 , drome-CG4382 , drome-CG4390 , drome-CG4572 , drome-CG4582 , drome-CG4851 , drome-CG4979 , drome-CG5068 , drome-CG5162 , drome-CG5355 , drome-CG5377 , drome-CG5397 , drome-CG5412 , drome-CG5665 , drome-CG5932 , drome-CG5966 , drome-CG6018 , drome-CG6113 , drome-CG6271 , drome-CG6283 , drome-CG6295 , drome-CG6296 , drome-CG6414 , drome-CG6431 , drome-CG6472 , drome-CG6567 , drome-CG6675 , drome-CG6753 , drome-CG6847 , drome-CG7329 , drome-CG7367 , drome-CG7529 , drome-CG7632 , drome-CG8058 , drome-CG8093 , drome-CG8233 , drome-CG8424 , drome-CG8425 , drome-CG9059 , drome-CG9186 , drome-CG9287 , drome-CG9289 , drome-CG9542 , drome-CG9858 , drome-CG9953 , drome-CG9966 , drome-CG10116 , drome-CG10163 , drome-CG10175 , drome-CG10339 , drome-CG10357 , drome-CG10982 , drome-CG11034 , drome-CG11055 , drome-CG11309 , drome-CG11319 , drome-CG11406 , drome-CG11598 , drome-CG11600 , drome-CG11608 , drome-CG11626 , drome-CG11935 , drome-CG12108 , drome-CG12869 , drome-CG13282 , drome-CG13562 , drome-CG13772 , drome-CG14034 , drome-nlg3 , drome-CG14717 , drome-CG15101 , drome-CG15102 , drome-CG15106 , drome-CG15111 , drome-CG15820 , drome-CG15821 , drome-CG15879 , drome-CG17097 , drome-CG17099 , drome-CG17101 , drome-CG17191 , drome-CG17192 , drome-CG17292 , drome-CG18258 , drome-CG18284 , drome-CG18301 , drome-CG18302 , drome-CG18493 , drome-CG18530 , drome-CG18641 , drome-CG18815 , drome-CG31089 , drome-CG31091 , drome-CG32333 , drome-CG32483 , drome-CG33174 , drome-dnlg1 , drome-este4 , drome-este6 , drome-GH02384 , drome-GH02439 , drome-glita , drome-KRAKEN , drome-lip1 , drome-LIP2 , drome-lip3 , drome-MESK2 , drome-nrtac , drome-OME , drome-q7k274 , drome-Q9VJN0 , drome-Q8IP31 , drome-q9vux3 , drome-q8mqj5