Feruloyl

General

Ferulic acid is a hydroxycinnamic acid derivative and a phenolic compound. It is an organic compound with the formula (CH3O)HOC6H3CH=CHCO2H. The name is derived from the genus Ferula, referring to the giant fennel (Ferula communis). Esters of ferulic acid are found in plant cell walls, covalently bonded to hemicellulose such as arabinoxylans. Salts and esters derived from ferulic acid are called ferulates.

Inhibitor	Main targeted enzyme families	Type
Nlrp3-IN-33-Cpd12o	ACHE BCHE	Acrylate Feruloyl Quinoline Hydroxycinnamic-ester Multitarget NLRP3 inflammasome activation
Tacrine-cinnamic-hybrid-cpd10g	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Hydroxycinnamic-ester Alkyl linked bis-ligand
CHEMBL4533477	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand pNP
CHEMBL4534662	ACHE BCHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand
CHEMBL4085222	BCHE	Derivative of Donepezil Piperidine Quinoline Feruloyl Isoquinoline Benzylpiperidine
Deriv-CHEMBL4085222-Cpd8e	BCHE	Feruloyl Derivative of Donepezil Piperidine Quinoline Benzylpiperidine
Ferulic-Acid-Piperazine-Cpd13a	ACHE	Multitarget Piperazine Quinoline Feruloyl Metal ion chelator anti-Abeta-aggregation Antioxidant
BuChE-IN-TM-10	BCHE	Feruloyl Hydroxycinnamic-ester Multitarget Isoquinoline Monoamine-oxidase-inhibitor
Tetracyclic-carbamate-ferulicacid-4a	BCHE	Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Feruloyl Antioxidant Alkyl linked bis-ligand
Tacrine-Melatonin-Feruloyl-5c	BCHE ACHE	Derivative of Tacrine Acridine Derivative of Tryptamine Indole Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand Nrf2 modulator
Avenanthramide-B	Carboxylesterase Carb_B_Chordata	Natural Feruloyl Benzoate
Nlrp3-IN-33-Cpd12o	ACHE BCHE	Acrylate Feruloyl Quinoline Hydroxycinnamic-ester Multitarget NLRP3 inflammasome activation
Tacrine-cinnamic-hybrid-cpd10g	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Hydroxycinnamic-ester Alkyl linked bis-ligand
CHEMBL4533477	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand pNP
CHEMBL4534662	ACHE BCHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand
CHEMBL4085222	BCHE	Derivative of Donepezil Piperidine Quinoline Feruloyl Isoquinoline Benzylpiperidine
Deriv-CHEMBL4085222-Cpd8e	BCHE	Feruloyl Derivative of Donepezil Piperidine Quinoline Benzylpiperidine
Ferulic-Acid-Piperazine-Cpd13a	ACHE	Multitarget Piperazine Quinoline Feruloyl Metal ion chelator anti-Abeta-aggregation Antioxidant
BuChE-IN-TM-10	BCHE	Feruloyl Hydroxycinnamic-ester Multitarget Isoquinoline Monoamine-oxidase-inhibitor
Tetracyclic-carbamate-ferulicacid-4a	BCHE	Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Feruloyl Antioxidant Alkyl linked bis-ligand
Tacrine-Melatonin-Feruloyl-5c	BCHE ACHE	Derivative of Tacrine Acridine Derivative of Tryptamine Indole Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand Nrf2 modulator
Avenanthramide-B	Carboxylesterase Carb_B_Chordata	Natural Feruloyl Benzoate
Nlrp3-IN-33-Cpd12o	ACHE BCHE	Acrylate Feruloyl Quinoline Hydroxycinnamic-ester Multitarget NLRP3 inflammasome activation
Tacrine-cinnamic-hybrid-cpd10g	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Hydroxycinnamic-ester Alkyl linked bis-ligand
CHEMBL4533477	ACHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand pNP
CHEMBL4534662	ACHE BCHE	Derivative of Tacrine Acridine Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand
CHEMBL4085222	BCHE	Derivative of Donepezil Piperidine Quinoline Feruloyl Isoquinoline Benzylpiperidine
Deriv-CHEMBL4085222-Cpd8e	BCHE	Feruloyl Derivative of Donepezil Piperidine Quinoline Benzylpiperidine
Ferulic-Acid-Piperazine-Cpd13a	ACHE	Multitarget Piperazine Quinoline Feruloyl Metal ion chelator anti-Abeta-aggregation Antioxidant
BuChE-IN-TM-10	BCHE	Feruloyl Hydroxycinnamic-ester Multitarget Isoquinoline Monoamine-oxidase-inhibitor
Tetracyclic-carbamate-ferulicacid-4a	BCHE	Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Feruloyl Antioxidant Alkyl linked bis-ligand
Tacrine-Melatonin-Feruloyl-5c	BCHE ACHE	Derivative of Tacrine Acridine Derivative of Tryptamine Indole Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand Nrf2 modulator
Avenanthramide-B	Carboxylesterase Carb_B_Chordata	Natural Feruloyl Benzoate