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| Title : Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies - Panek_2023_Eur.J.Med.Chem_249_115135 |
| Author(s) : Panek D , Pasieka A , Latacz G , Zareba P , Szczech M , Godyn J , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Walczak M , Smolik M , Salat K , Hofner G , Wanner K , Wieckowska A , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 249 :115135 , 2023 |
| Abstract : Panek_2023_Eur.J.Med.Chem_249_115135 |
| ESTHER : Panek_2023_Eur.J.Med.Chem_249_115135 |
| PubMedSearch : Panek_2023_Eur.J.Med.Chem_249_115135 |
| PubMedID: 36696766 |
| Gene_locus related to this paper: human-BCHE |
| Title : Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and beta-amyloid inhibitors for the treatment of Alzheimer's disease - Pasieka_2023_Bioorg.Med.Chem_88-89_117333 |
| Author(s) : Pasieka A , Panek D , Zareba P , Slugocka E , Gucwa N , Espargaro A , Latacz G , Khan N , Bucki A , Sabate R , Wieckowska A , Malawska B |
| Ref : Bioorganic & Medicinal Chemistry , 88-89 :117333 , 2023 |
| Abstract : Pasieka_2023_Bioorg.Med.Chem_88-89_117333 |
| ESTHER : Pasieka_2023_Bioorg.Med.Chem_88-89_117333 |
| PubMedSearch : Pasieka_2023_Bioorg.Med.Chem_88-89_117333 |
| PubMedID: 37236021 |
| Title : Guanidines: Synthesis of Novel Histamine H(3)R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect - Staszewski_2023_Pharmaceuticals.(Basel)_16_ |
| Author(s) : Staszewski M , Iwan M , Werner T , Bajda M , Godyn J , Latacz G , Korga-Plewko A , Kubik J , Szalaj N , Stark H , Malawska B , Wieckowska A , Walczynski K |
| Ref : Pharmaceuticals (Basel) , 16 : , 2023 |
| Abstract : Staszewski_2023_Pharmaceuticals.(Basel)_16_ |
| ESTHER : Staszewski_2023_Pharmaceuticals.(Basel)_16_ |
| PubMedSearch : Staszewski_2023_Pharmaceuticals.(Basel)_16_ |
| PubMedID: 37242458 |
| Title : Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, beta-secretase, and amyloid beta aggregation as potential treatment of Alzheimer's disease - Zareba_2023_Eur.J.Med.Chem_261_115832 |
| Author(s) : Zareba P , Latka K , Mazur G , Gryzlo B , Pasieka A , Godyn J , Panek D , Skrzypczak-Wiercioch A , Hofner GC , Latacz G , Maj M , Espargaro A , Sabate R , Jozwiak K , Wanner KT , Salat K , Malawska B , Kulig K , Bajda M |
| Ref : Eur Journal of Medicinal Chemistry , 261 :115832 , 2023 |
| Abstract : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| ESTHER : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| PubMedSearch : Zareba_2023_Eur.J.Med.Chem_261_115832 |
| PubMedID: 37837674 |
| Title : Benzophenone Derivatives with Histamine H(3) Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease - Godyn_2022_Molecules_28_ |
| Author(s) : Godyn J , Zareba P , Stary D , Kaleta M , Kuder KJ , Latacz G , Mogilski S , Reiner-Link D , Frank A , Doroz-Plonka A , Olejarz-Maciej A , Sudol-Talaj S , Nolte T , Handzlik J , Stark H , Wieckowska A , Malawska B , Kiec-Kononowicz K , Lazewska D , Bajda M |
| Ref : Molecules , 28 : , 2022 |
| Abstract : Godyn_2022_Molecules_28_ |
| ESTHER : Godyn_2022_Molecules_28_ |
| PubMedSearch : Godyn_2022_Molecules_28_ |
| PubMedID: 36615435 |
| Title : Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters - Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| Author(s) : Pasieka A , Panek D , Jonczyk J , Godyn J , Szalaj N , Latacz G , Tabor J , Mezeiova E , Chantegreil F , Dias J , Knez D , Lu J , Pi R , Korabecny J , Brazzolotto X , Gobec S , Hofner G , Wanner K , Wieckowska Q , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 218 :113397 , 2021 |
| Abstract : Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| ESTHER : Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| PubMedSearch : Pasieka_2021_Eur.J.Med.Chem_218_113397 |
| PubMedID: 33838585 |
| Title : Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT(6) receptor with anti-aggregation properties against amyloid-beta and tau - Wichur_2021_Eur.J.Med.Chem_225_113783 |
| Author(s) : Wichur T , Pasieka A , Godyn J , Panek D , Goral I , Latacz G , Honkisz-Orzechowska E , Bucki A , Siwek A , Gluch-Lutwin M , Knez D , Brazzolotto X , Gobec S , Kolaczkowski M , Sabate R , Malawska B , Wieckowska A |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113783 , 2021 |
| Abstract : Wichur_2021_Eur.J.Med.Chem_225_113783 |
| ESTHER : Wichur_2021_Eur.J.Med.Chem_225_113783 |
| PubMedSearch : Wichur_2021_Eur.J.Med.Chem_225_113783 |
| PubMedID: 34461507 |
| Title : Biphenylalkoxyamine Derivatives-Histamine H(3) Receptor Ligands with Butyrylcholinesterase Inhibitory Activity - Lazewska_2021_Molecules_26_ |
| Author(s) : Lazewska D , Zareba P , Godyn J , Doroz-Plonka A , Frank A , Reiner-Link D , Bajda M , Stary D , Mogilski S , Olejarz-Maciej A , Kaleta M , Stark H , Malawska B , Kiec-Kononowicz K |
| Ref : Molecules , 26 : , 2021 |
| Abstract : Lazewska_2021_Molecules_26_ |
| ESTHER : Lazewska_2021_Molecules_26_ |
| PubMedSearch : Lazewska_2021_Molecules_26_ |
| PubMedID: 34208297 |
| Title : Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT6R antagonists with beta-amyloid anti-aggregation properties - Wichur_2021_Eur.J.Med.Chem_225_113792 |
| Author(s) : Wichur T , Godyn J , Goral I , Latacz G , Bucki A , Siwek A , Gluch-Lutwin M , Mordyl B , Sniecikowska J , Walczak M , Knez D , Jukic M , Salat K , Gobec S , Kolaczkowski M , Malawska B , Brazzolotto X , Wieckowska A |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113792 , 2021 |
| Abstract : Wichur_2021_Eur.J.Med.Chem_225_113792 |
| ESTHER : Wichur_2021_Eur.J.Med.Chem_225_113792 |
| PubMedSearch : Wichur_2021_Eur.J.Med.Chem_225_113792 |
| PubMedID: 34530376 |
| Gene_locus related to this paper: human-BCHE |
| Title : Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase - Jonczyk_2021_Biomolecules_11_ |
| Author(s) : Jonczyk J , Kukulowicz J , Aatka K , Malawska B , Jung YS , Musilek K , Bajda M |
| Ref : Biomolecules , 11 : , 2021 |
| Abstract : Jonczyk_2021_Biomolecules_11_ |
| ESTHER : Jonczyk_2021_Biomolecules_11_ |
| PubMedSearch : Jonczyk_2021_Biomolecules_11_ |
| PubMedID: 33513955 |
| Title : Cyanobiphenyls: Novel H(3) receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease - Godyn_2021_Bioorg.Chem_114_105129 |
| Author(s) : Godyn J , Zareba P , aewska D , Stary D , Reiner-Link D , Frank A , Latacz G , Mogilski S , Kaleta M , Doroz-Plonka A , Lubelska A , Honkisz-Orzechowska E , Olejarz-Maciej A , Handzlik J , Stark H , Kiec-Kononowicz K , Malawska B , Bajda M |
| Ref : Bioorg Chem , 114 :105129 , 2021 |
| Abstract : Godyn_2021_Bioorg.Chem_114_105129 |
| ESTHER : Godyn_2021_Bioorg.Chem_114_105129 |
| PubMedSearch : Godyn_2021_Bioorg.Chem_114_105129 |
| PubMedID: 34217977 |
| Title : Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates - Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| Author(s) : Lee HM , Andrys R , Jonczyk J , Kim K , Vishakantegowda AG , Malinak D , Skarka A , Schmidt M , Vaskova M , Latka K , Bajda M , Jung YS , Malawska B , Musilek K |
| Ref : J Enzyme Inhib Med Chem , 36 :437 , 2021 |
| Abstract : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| ESTHER : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| PubMedSearch : Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 |
| PubMedID: 33467931 |
| Title : Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity - Jonczyk_2020_Molecules_25_ |
| Author(s) : Jonczyk J , Godyn J , Stawarska E , Morak-Mlodawska B , Jelen M , Pluta K , Malawska B |
| Ref : Molecules , 25 : , 2020 |
| Abstract : Jonczyk_2020_Molecules_25_ |
| ESTHER : Jonczyk_2020_Molecules_25_ |
| PubMedSearch : Jonczyk_2020_Molecules_25_ |
| PubMedID: 32503288 |
| Title : Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease - Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944 |
| Author(s) : Szalaj N , Godyn J , Jonczyk J , Pasieka A , Panek D , Wichur T , Wieckowski K , Zareba P , Bajda M , Pislar A , Malawska B , Sabate R , Wieckowska A |
| Ref : J Enzyme Inhib Med Chem , 35 :1944 , 2020 |
| Abstract : Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944 |
| ESTHER : Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944 |
| PubMedSearch : Szalaj_2020_J.Enzyme.Inhib.Med.Chem_35_1944 |
| PubMedID: 33092411 |
| Title : Rational design of new multitarget histamine H(3) receptor ligands as potential candidates for treatment of Alzheimer's disease - Lazewska_2020_Eur.J.Med.Chem_207_112743 |
| Author(s) : Lazewska D , Bajda M , Kaleta M , Zareba P , Doroz-Plonka A , Siwek A , Alachkar A , Mogilski S , Saad A , Kuder K , Olejarz-Maciej A , Godyn J , Stary D , Sudol S , Wiecek M , Latacz G , Walczak M , Handzlik J , Sadek B , Malawska B , Kiec-Kononowicz K |
| Ref : Eur Journal of Medicinal Chemistry , 207 :112743 , 2020 |
| Abstract : Lazewska_2020_Eur.J.Med.Chem_207_112743 |
| ESTHER : Lazewska_2020_Eur.J.Med.Chem_207_112743 |
| PubMedSearch : Lazewska_2020_Eur.J.Med.Chem_207_112743 |
| PubMedID: 32882609 |
| Title : New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition - Malek_2019_J.Med.Chem_62_11416 |
| Author(s) : Malek R , Arribas RL , Palomino-Antolin A , Totoson P , Demougeot C , Kobrlova T , Soukup O , Iriepa I , Moraleda I , Diez-Iriepa D , Godyn J , Panek D , Malawska B , Gluch-Lutwin M , Mordyl B , Siwek A , Chabchoub F , Marco-Contelles J , Kiec-Kononowicz K , Egea J , de los Rios C , Ismaili L |
| Ref : Journal of Medicinal Chemistry , 62 :11416 , 2019 |
| Abstract : Malek_2019_J.Med.Chem_62_11416 |
| ESTHER : Malek_2019_J.Med.Chem_62_11416 |
| PubMedSearch : Malek_2019_J.Med.Chem_62_11416 |
| PubMedID: 31724859 |
| Title : 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease - Wichur_2019_Eur.J.Med.Chem_187_111916 |
| Author(s) : Wichur T , Wieckowska A , Wieckowski K , Godyn J , Jonczyk J , Valdivieso ADR , Panek D , Pasieka A , Sabate R , Knez D , Gobec S , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 187 :111916 , 2019 |
| Abstract : Wichur_2019_Eur.J.Med.Chem_187_111916 |
| ESTHER : Wichur_2019_Eur.J.Med.Chem_187_111916 |
| PubMedSearch : Wichur_2019_Eur.J.Med.Chem_187_111916 |
| PubMedID: 31812794 |
| Title : Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives - Jonczyk_2019_Bioorg.Chem_90_103084 |
| Author(s) : Jonczyk J , Lodarski K , Staszewski M , Godyn J , Zareba P , Soukup O , Janockova J , Korabecny J , Salat K , Malikowska-Racia N , Hebda M , Szalaj N , Filipek B , Walczynski K , Malawska B , Bajda M |
| Ref : Bioorg Chem , 90 :103084 , 2019 |
| Abstract : Jonczyk_2019_Bioorg.Chem_90_103084 |
| ESTHER : Jonczyk_2019_Bioorg.Chem_90_103084 |
| PubMedSearch : Jonczyk_2019_Bioorg.Chem_90_103084 |
| PubMedID: 31271942 |
| Title : Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands - Bajda_2019_Eur.J.Med.Chem_185_111785 |
| Author(s) : Bajda M , Lazewska D , Godyn J , Zareba P , Kuder K , Hagenow S , Latka K , Stawarska E , Stark H , Kiec-Kononowicz K , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 185 :111785 , 2019 |
| Abstract : Bajda_2019_Eur.J.Med.Chem_185_111785 |
| ESTHER : Bajda_2019_Eur.J.Med.Chem_185_111785 |
| PubMedSearch : Bajda_2019_Eur.J.Med.Chem_185_111785 |
| PubMedID: 31669851 |
| Title : Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents - Panek_2018_ACS.Chem.Neurosci_9_1074 |
| Author(s) : Panek D , Wieckowska A , Jonczyk J , Godyn J , Bajda M , Wichur T , Pasieka A , Knez D , Pislar A , Korabecny J , Soukup O , Sepsova V , Sabate R , Kos J , Gobec S , Malawska B |
| Ref : ACS Chem Neurosci , 9 :1074 , 2018 |
| Abstract : Panek_2018_ACS.Chem.Neurosci_9_1074 |
| ESTHER : Panek_2018_ACS.Chem.Neurosci_9_1074 |
| PubMedSearch : Panek_2018_ACS.Chem.Neurosci_9_1074 |
| PubMedID: 29345897 |
| Title : Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease - Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
| Author(s) : Wieckowska A , Wichur T , Godyn J , Bucki A , Marcinkowska M , Siwek A , Wieckowski K , Zareba P , Knez D , Gluch-Lutwin M , Kazek G , Latacz G , Mika K , Kolaczkowski M , Korabecny J , Soukup O , Benkova M , Kiec-Kononowicz K , Gobec S , Malawska B |
| Ref : ACS Chem Neurosci , 9 :1195 , 2018 |
| Abstract : Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
| ESTHER : Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
| PubMedSearch : Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
| PubMedID: 29384656 |
| Title : Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents - Panek_2018_Molecules_23_ |
| Author(s) : Panek D , Wieckowska A , Pasieka A , Godyn J , Jonczyk J , Bajda M , Knez D , Gobec S , Malawska B |
| Ref : Molecules , 23 : , 2018 |
| Abstract : Panek_2018_Molecules_23_ |
| ESTHER : Panek_2018_Molecules_23_ |
| PubMedSearch : Panek_2018_Molecules_23_ |
| PubMedID: 29414887 |
| Title : Novel carbamate derivatives as selective butyrylcholinesterase inhibitors - Bajda_2018_Bioorg.Chem_78_29 |
| Author(s) : Bajda M , Latka K , Hebda M , Jonczyk J , Malawska B |
| Ref : Bioorg Chem , 78 :29 , 2018 |
| Abstract : Bajda_2018_Bioorg.Chem_78_29 |
| ESTHER : Bajda_2018_Bioorg.Chem_78_29 |
| PubMedSearch : Bajda_2018_Bioorg.Chem_78_29 |
| PubMedID: 29529519 |
| Title : Lipophilic properties of anti-Alzheimer's agents determined by micellar electrokinetic chromatography and reversed-phase thin-layer chromatography - Godyn_2017_Electrophoresis_38_1268 |
| Author(s) : Godyn J , Hebda M , Wieckowska A , Wieckowski K , Malawska B , Bajda M |
| Ref : Electrophoresis , 38 :1268 , 2017 |
| Abstract : Godyn_2017_Electrophoresis_38_1268 |
| ESTHER : Godyn_2017_Electrophoresis_38_1268 |
| PubMedSearch : Godyn_2017_Electrophoresis_38_1268 |
| PubMedID: 28169440 |
| Title : Advances toward multifunctional cholinesterase and beta-amyloid aggregation inhibitors - Panek_2017_Future.Med.Chem_9_1835 |
| Author(s) : Panek D , Wichur T , Godyn J , Pasieka A , Malawska B |
| Ref : Future Med Chem , 9 :1835 , 2017 |
| Abstract : Panek_2017_Future.Med.Chem_9_1835 |
| ESTHER : Panek_2017_Future.Med.Chem_9_1835 |
| PubMedSearch : Panek_2017_Future.Med.Chem_9_1835 |
| PubMedID: 28925729 |
| Title : Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment - Czarnecka_2017_Bioorg.Chem_72_315 |
| Author(s) : Czarnecka K , Szymanski P , Girek M , Mikiciuk-Olasik E , Skibinski R , Kabzinski J , Majsterek I , Malawska B , Jonczyk J , Bajda M |
| Ref : Bioorg Chem , 72 :315 , 2017 |
| Abstract : Czarnecka_2017_Bioorg.Chem_72_315 |
| ESTHER : Czarnecka_2017_Bioorg.Chem_72_315 |
| PubMedSearch : Czarnecka_2017_Bioorg.Chem_72_315 |
| PubMedID: 28501648 |
| Title : Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation - Panek_2016_Eur.J.Med.Chem_125_676 |
| Author(s) : Panek D , Wieckowska A , Wichur T , Bajda M , Godyn J , Jonczyk J , Mika K , Janockova J , Soukup O , Knez D , Korabecny J , Gobec S , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 125 :676 , 2016 |
| Abstract : Panek_2016_Eur.J.Med.Chem_125_676 |
| ESTHER : Panek_2016_Eur.J.Med.Chem_125_676 |
| PubMedSearch : Panek_2016_Eur.J.Med.Chem_125_676 |
| PubMedID: 27721153 |
| Title : Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy - Dgachi_2016_Eur.J.Med.Chem_126_576 |
| Author(s) : Dgachi Y , Sokolov O , Luzet V , Godyn J , Panek D , Bonet A , Martin H , Iriepa I , Moraleda I , Garcia-Iriepa C , Janockova J , Richert L , Soukup O , Malawska B , Chabchoub F , Marco-Contelles J , Ismaili L |
| Ref : Eur Journal of Medicinal Chemistry , 126 :576 , 2016 |
| Abstract : Dgachi_2016_Eur.J.Med.Chem_126_576 |
| ESTHER : Dgachi_2016_Eur.J.Med.Chem_126_576 |
| PubMedSearch : Dgachi_2016_Eur.J.Med.Chem_126_576 |
| PubMedID: 27918993 |
| Title : Development of an in-vivo active reversible butyrylcholinesterase inhibitor - Kosak_2016_Sci.Rep_6_39495 |
| Author(s) : Kosak U , Brus B , Knez D , Sink R , Zakelj S , Trontelj J , Pislar A , Slenc J , Gobec M , Zivin M , Tratnjek L , Perse M , Salat K , Podkowa A , Filipek B , Nachon F , Brazzolotto X , Wieckowska A , Malawska B , Stojan J , Rascan IM , Kos J , Coquelle N , Colletier JP , Gobec S |
| Ref : Sci Rep , 6 :39495 , 2016 |
| Abstract : Kosak_2016_Sci.Rep_6_39495 |
| ESTHER : Kosak_2016_Sci.Rep_6_39495 |
| PubMedSearch : Kosak_2016_Sci.Rep_6_39495 |
| PubMedID: 28000737 |
| Gene_locus related to this paper: human-BCHE |
| Title : Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Abeta1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy - Dgachi_2016_ChemMedChem_11_1318 |
| Author(s) : Dgachi Y , Ismaili L , Knez D , Benchekroun M , Martin H , Szalaj N , Wehle S , Bautista-Aguilera OM , Luzet V , Bonnet A , Malawska B , Gobec S , Chioua M , Decker M , Chabchoub F , Marco-Contelles J |
| Ref : ChemMedChem , 11 :1318 , 2016 |
| Abstract : Dgachi_2016_ChemMedChem_11_1318 |
| ESTHER : Dgachi_2016_ChemMedChem_11_1318 |
| PubMedSearch : Dgachi_2016_ChemMedChem_11_1318 |
| PubMedID: 26804623 |
| Title : Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation - Wieckowska_2016_Eur.J.Med.Chem_124_63 |
| Author(s) : Wieckowska A , Kolaczkowski M , Bucki A , Godyn J , Marcinkowska M , Wieckowski K , Zareba P , Siwek A , Kazek G , Gluch-Lutwin M , Mierzejewski P , Bienkowski P , Sienkiewicz-Jarosz H , Knez D , Wichur T , Gobec S , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 124 :63 , 2016 |
| Abstract : Wieckowska_2016_Eur.J.Med.Chem_124_63 |
| ESTHER : Wieckowska_2016_Eur.J.Med.Chem_124_63 |
| PubMedSearch : Wieckowska_2016_Eur.J.Med.Chem_124_63 |
| PubMedID: 27560283 |
| Title : Therapeutic strategies for Alzheimer's disease in clinical trials - Godyn_2016_Pharmacol.Rep_68_127 |
| Author(s) : Godyn J , Jonczyk J , Panek D , Malawska B |
| Ref : Pharmacol Rep , 68 :127 , 2016 |
| Abstract : Godyn_2016_Pharmacol.Rep_68_127 |
| ESTHER : Godyn_2016_Pharmacol.Rep_68_127 |
| PubMedSearch : Godyn_2016_Pharmacol.Rep_68_127 |
| PubMedID: 26721364 |
| Title : Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta - Hebda_2016_Molecules_21_ |
| Author(s) : Hebda M , Bajda M , Wieckowska A , Szalaj N , Pasieka A , Panek D , Godyn J , Wichur T , Knez D , Gobec S , Malawska B |
| Ref : Molecules , 21 : , 2016 |
| Abstract : Hebda_2016_Molecules_21_ |
| ESTHER : Hebda_2016_Molecules_21_ |
| PubMedSearch : Hebda_2016_Molecules_21_ |
| PubMedID: 27023510 |
| Title : Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands - Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140 |
| Author(s) : Lazewska D , Jonczyk J , Bajda M , Szalaj N , Wieckowska A , Panek D , Moore C , Kuder K , Malawska B , Kiec-Kononowicz K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 26 :4140 , 2016 |
| Abstract : Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140 |
| ESTHER : Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140 |
| PubMedSearch : Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140 |
| PubMedID: 27445168 |
| Title : Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease - Dgachi_2016_Molecules_21_ |
| Author(s) : Dgachi Y , Bautista-Aguilera OM , Benchekroun M , Martin H , Bonet A , Knez D , Godyn J , Malawska B , Gobec S , Chioua M , Janockova J , Soukup O , Chabchoub F , Marco-Contelles J , Ismaili L |
| Ref : Molecules , 21 : , 2016 |
| Abstract : Dgachi_2016_Molecules_21_ |
| ESTHER : Dgachi_2016_Molecules_21_ |
| PubMedSearch : Dgachi_2016_Molecules_21_ |
| PubMedID: 27187348 |
| Title : Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and beta-amyloid aggregation inhibitors with neuroprotective properties - Guzior_2015_Eur.J.Med.Chem_92C_738 |
| Author(s) : Guzior N , Bajda M , Skrok M , Kurpiewska K , Lewinski K , Brus B , Pislar A , Kos J , Gobec S , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 92C :738 , 2015 |
| Abstract : Guzior_2015_Eur.J.Med.Chem_92C_738 |
| ESTHER : Guzior_2015_Eur.J.Med.Chem_92C_738 |
| PubMedSearch : Guzior_2015_Eur.J.Med.Chem_92C_738 |
| PubMedID: 25621991 |
| Title : Multiple Ligands Targeting Cholinesterases and beta-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore - Szalaj_2015_Arch.Pharm.(Weinheim)_348_556 |
| Author(s) : Szalaj N , Bajda M , Dudek K , Brus B , Gobec S , Malawska B |
| Ref : Arch Pharm (Weinheim) , 348 :556 , 2015 |
| Abstract : Szalaj_2015_Arch.Pharm.(Weinheim)_348_556 |
| ESTHER : Szalaj_2015_Arch.Pharm.(Weinheim)_348_556 |
| PubMedSearch : Szalaj_2015_Arch.Pharm.(Weinheim)_348_556 |
| PubMedID: 26032855 |
| Title : Isoindoline-1,3-dione derivatives targeting cholinesterases: Design, synthesis and biological evaluation of potential anti-Alzheimer's agents - Guzior_2015_Bioorg.Med.Chem_23_1629 |
| Author(s) : Guzior N , Bajda M , Rakoczy J , Brus B , Gobec S , Malawska B |
| Ref : Bioorganic & Medicinal Chemistry , 23 :1629 , 2015 |
| Abstract : Guzior_2015_Bioorg.Med.Chem_23_1629 |
| ESTHER : Guzior_2015_Bioorg.Med.Chem_23_1629 |
| PubMedSearch : Guzior_2015_Bioorg.Med.Chem_23_1629 |
| PubMedID: 25707322 |
| Title : Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease - Guzior_2015_Curr.Med.Chem_22_373 |
| Author(s) : Guzior N , Wieckowska A , Panek D , Malawska B |
| Ref : Curr Med Chem , 22 :373 , 2015 |
| Abstract : Guzior_2015_Curr.Med.Chem_22_373 |
| ESTHER : Guzior_2015_Curr.Med.Chem_22_373 |
| PubMedSearch : Guzior_2015_Curr.Med.Chem_22_373 |
| PubMedID: 25386820 |
| Title : SEARCH FOR POTENTIAL CHOLINESTERASE INHIBITORS FROM THE ZINC DATABASE BY VIRTUAL SCREENING METHOD - Bajda_2015_Acta.Pol.Pharm_72_737 |
| Author(s) : Bajda M , Panek D , Hebda M , Wieckowska A , Guzior N , Malawska B |
| Ref : Acta Pol Pharm , 72 :737 , 2015 |
| Abstract : Bajda_2015_Acta.Pol.Pharm_72_737 |
| ESTHER : Bajda_2015_Acta.Pol.Pharm_72_737 |
| PubMedSearch : Bajda_2015_Acta.Pol.Pharm_72_737 |
| PubMedID: 26647631 |
| Title : Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines - Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98 |
| Author(s) : Lodarski K , Jonczyk J , Guzior N , Bajda M , Gladysz J , Walczyk J , Jelen M , Morak-Mlodawska B , Pluta K , Malawska B |
| Ref : J Enzyme Inhib Med Chem , 30 :98 , 2015 |
| Abstract : Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98 |
| ESTHER : Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98 |
| PubMedSearch : Lodarski_2015_J.Enzyme.Inhib.Med.Chem_30_98 |
| PubMedID: 24666296 |
| Title : Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease - Bajda_2015_Bioorg.Med.Chem_23_5610 |
| Author(s) : Bajda M , Jonczyk J , Malawska B , Czarnecka K , Girek M , Olszewska P , Sikora J , Mikiciuk-Olasik E , Skibinski R , Gumieniczek A , Szymanski P |
| Ref : Bioorganic & Medicinal Chemistry , 23 :5610 , 2015 |
| Abstract : Bajda_2015_Bioorg.Med.Chem_23_5610 |
| ESTHER : Bajda_2015_Bioorg.Med.Chem_23_5610 |
| PubMedSearch : Bajda_2015_Bioorg.Med.Chem_23_5610 |
| PubMedID: 26242241 |
| Title : Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with beta-amyloid anti-aggregation properties and beneficial effects on memory in vivo - Wieckowska_2015_Bioorg.Med.Chem_23_2445 |
| Author(s) : Wieckowska A , Wieckowski K , Bajda M , Brus B , Salat K , Czerwinska P , Gobec S , Filipek B , Malawska B |
| Ref : Bioorganic & Medicinal Chemistry , 23 :2445 , 2015 |
| Abstract : Wieckowska_2015_Bioorg.Med.Chem_23_2445 |
| ESTHER : Wieckowska_2015_Bioorg.Med.Chem_23_2445 |
| PubMedSearch : Wieckowska_2015_Bioorg.Med.Chem_23_2445 |
| PubMedID: 25868744 |
| Title : New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis - Szymanski_2013_Molecules_18_2878 |
| Author(s) : Szymanski P , Skibinski R , Inglot T , Bajda M , Jonczyk J , Malawska B , Mikiciuk-Olasik E |
| Ref : Molecules , 18 :2878 , 2013 |
| Abstract : Szymanski_2013_Molecules_18_2878 |
| ESTHER : Szymanski_2013_Molecules_18_2878 |
| PubMedSearch : Szymanski_2013_Molecules_18_2878 |
| PubMedID: 23459299 |
| Title : Structure-based search for new inhibitors of cholinesterases - Bajda_2013_Int.J.Mol.Sci_14_5608 |
| Author(s) : Bajda M , Wieckowska A , Hebda M , Guzior N , Sotriffer CA , Malawska B |
| Ref : Int J Mol Sci , 14 :5608 , 2013 |
| Abstract : Bajda_2013_Int.J.Mol.Sci_14_5608 |
| ESTHER : Bajda_2013_Int.J.Mol.Sci_14_5608 |
| PubMedSearch : Bajda_2013_Int.J.Mol.Sci_14_5608 |
| PubMedID: 23478436 |
| Title : Design, synthesis and evaluation of novel 2-(aminoalkyl)-isoindoline-1,3-dione derivatives as dual-binding site acetylcholinesterase inhibitors - Ignasik_2012_Arch.Pharm.(Weinheim)_345_509 |
| Author(s) : Ignasik M , Bajda M , Guzior N , Prinz M , Holzgrabe U , Malawska B |
| Ref : Arch Pharm (Weinheim) , 345 :509 , 2012 |
| Abstract : Ignasik_2012_Arch.Pharm.(Weinheim)_345_509 |
| ESTHER : Ignasik_2012_Arch.Pharm.(Weinheim)_345_509 |
| PubMedSearch : Ignasik_2012_Arch.Pharm.(Weinheim)_345_509 |
| PubMedID: 22467516 |
| Title : Synthesis, biological activity and molecular modeling of 4-fluoro-N-[omega-(1,2,3,4-tetrahydroacridin-9-ylamino)-alkyl]-benzamide derivatives as cholinesterase inhibitors - Szymanski_2012_Arzneimittelforschung_62_655 |
| Author(s) : Szymanski P , Markowicz M , Bajda M , Malawska B , Mikiciuk-Olasik E |
| Ref : Arzneimittelforschung , 62 :655 , 2012 |
| Abstract : Szymanski_2012_Arzneimittelforschung_62_655 |
| ESTHER : Szymanski_2012_Arzneimittelforschung_62_655 |
| PubMedSearch : Szymanski_2012_Arzneimittelforschung_62_655 |
| PubMedID: 23154886 |
| Title : 2,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution - Szymanski_2012_Int.J.Mol.Sci_13_10067 |
| Author(s) : Szymanski P , Laznickova A , Laznicek M , Bajda M , Malawska B , Markowicz M , Mikiciuk-Olasik E |
| Ref : Int J Mol Sci , 13 :10067 , 2012 |
| Abstract : Szymanski_2012_Int.J.Mol.Sci_13_10067 |
| ESTHER : Szymanski_2012_Int.J.Mol.Sci_13_10067 |
| PubMedSearch : Szymanski_2012_Int.J.Mol.Sci_13_10067 |
| PubMedID: 22949848 |
| Title : Multi-target-directed ligands in Alzheimer's disease treatment - Bajda_2011_Curr.Med.Chem_18_4949 |
| Author(s) : Bajda M , Guzior N , Ignasik M , Malawska B |
| Ref : Curr Med Chem , 18 :4949 , 2011 |
| Abstract : Bajda_2011_Curr.Med.Chem_18_4949 |
| ESTHER : Bajda_2011_Curr.Med.Chem_18_4949 |
| PubMedSearch : Bajda_2011_Curr.Med.Chem_18_4949 |
| PubMedID: 22050745 |
| Title : Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors - Wieckowska_2010_Eur.J.Med.Chem_45_5602 |
| Author(s) : Wieckowska A , Bajda M , Guzior N , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 45 :5602 , 2010 |
| Abstract : Wieckowska_2010_Eur.J.Med.Chem_45_5602 |
| ESTHER : Wieckowska_2010_Eur.J.Med.Chem_45_5602 |
| PubMedSearch : Wieckowska_2010_Eur.J.Med.Chem_45_5602 |
| PubMedID: 20926161 |
| Title : Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors - Bajda_2009_Acta.Pol.Pharm_66_357 |
| Author(s) : Bajda M , Wieckowska A , Malawska B |
| Ref : Acta Pol Pharm , 66 :357 , 2009 |
| Abstract : Bajda_2009_Acta.Pol.Pharm_66_357 |
| ESTHER : Bajda_2009_Acta.Pol.Pharm_66_357 |
| PubMedSearch : Bajda_2009_Acta.Pol.Pharm_66_357 |
| PubMedID: 19702166 |
| Title : Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment - Musial_2007_Curr.Med.Chem_14_2654 |
| Author(s) : Musial A , Bajda M , Malawska B |
| Ref : Curr Med Chem , 14 :2654 , 2007 |
| Abstract : Musial_2007_Curr.Med.Chem_14_2654 |
| ESTHER : Musial_2007_Curr.Med.Chem_14_2654 |
| PubMedSearch : Musial_2007_Curr.Med.Chem_14_2654 |
| PubMedID: 17979717 |
| Title : Synthesis of novel N-alkyl carbamates of a-substituted amides of g-hydroxybutyric acid as potential acetylcholinesterase inhibitors - Musial_2004_Acta.Pol.Pharm_61 Suppl_94 |
| Author(s) : Musial A , Malawska B |
| Ref : Acta Pol Pharm , 61 Suppl :94 , 2004 |
| Abstract : Musial_2004_Acta.Pol.Pharm_61 Suppl_94 |
| ESTHER : Musial_2004_Acta.Pol.Pharm_61 Suppl_94 |
| PubMedSearch : Musial_2004_Acta.Pol.Pharm_61 Suppl_94 |
| PubMedID: 15909954 |