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Author Report for: Malawska B

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    Title: Discovery of new, highly potent and selective inhibitors of BuChE - Design, synthesis, in vitro and in vivo evaluation and crystallography studies
    Panek D, Pasieka A, Latacz G, Zareba P, Szczech M, Godyn J, Chantegreil F, Nachon F, Brazzolotto X and Malawska B <7 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, :115135, 2023 : PubMed

            

    Title: Benzophenone Derivatives with Histamine H(3) Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease
    Godyn J, Zareba P, Stary D, Kaleta M, Kuder KJ, Latacz G, Mogilski S, Reiner-Link D, Frank A and Bajda M <10 more author(s)>
    Ref: Molecules, 28:, 2022 : PubMed

            

    Title: Cyanobiphenyls: Novel H(3) receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease
    Godyn J, Zareba P, aewska D, Stary D, Reiner-Link D, Frank A, Latacz G, Mogilski S, Kaleta M and Bajda M <8 more author(s)>
    Ref: Bioorg Chem, 114:105129, 2021 : PubMed

            

    Title: Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase
    Jonczyk J, Kukulowicz J, tka K, Malawska B, Jung YS, Musilek K, Bajda M
    Ref: Biomolecules, 11:, 2021 : PubMed

            

    Title: Biphenylalkoxyamine Derivatives-Histamine H(3) Receptor Ligands with Butyrylcholinesterase Inhibitory Activity
    Lazewska D, Zareba P, Godyn J, Doroz-Plonka A, Frank A, Reiner-Link D, Bajda M, Stary D, Mogilski S and Kiec-Kononowicz K <4 more author(s)>
    Ref: Molecules, 26:, 2021 : PubMed

            

    Title: Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates
    Lee HM, Andrys R, Jonczyk J, Kim K, Vishakantegowda AG, Malinak D, Skarka A, Schmidt M, Vaskova M and Musilek K <4 more author(s)>
    Ref: J Enzyme Inhib Med Chem, 36:437, 2021 : PubMed

            

    Title: Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters
    Pasieka A, Panek D, Jonczyk J, Godyn J, Szalaj N, Latacz G, Tabor J, Mezeiova E, Chantegreil F and Malawska B <10 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 218:113397,  : PubMed

            

    Title: Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT(6) receptor with anti-aggregation properties against amyloid-beta and tau
    Wichur T, Pasieka A, Godyn J, Panek D, Goral I, Latacz G, Honkisz-Orzechowska E, Bucki A, Siwek A and Wieckowska A <7 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 225:113783, 2021 : PubMed

            

    Title: Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT6R antagonists with beta-amyloid anti-aggregation properties
    Wichur T, Godyn J, Goral I, Latacz G, Bucki A, Siwek A, Gluch-Lutwin M, Mordyl B, Sniecikowska J and Wieckowska A <8 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 225:113792, 2021 : PubMed

            

    Title: Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity
    Jonczyk J, Godyn J, Stawarska E, Morak-Mlodawska B, Jelen M, Pluta K, Malawska B
    Ref: Molecules, 25:, 2020 : PubMed

            

    Title: Rational design of new multitarget histamine H(3) receptor ligands as potential candidates for treatment of Alzheimer's disease
    Lazewska D, Bajda M, Kaleta M, Zareba P, Doroz-Plonka A, Siwek A, Alachkar A, Mogilski S, Saad A and Kiec-Kononowicz K <11 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 207:112743, 2020 : PubMed

            

    Title: Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease
    Szalaj N, Godyn J, Jonczyk J, Pasieka A, Panek D, Wichur T, Wieckowski K, Zareba P, Bajda M and Wieckowska A <3 more author(s)>
    Ref: J Enzyme Inhib Med Chem, 35:1944, 2020 : PubMed

            

    Title: Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands
    Bajda M, Lazewska D, Godyn J, Zareba P, Kuder K, Hagenow S, Latka K, Stawarska E, Stark H and Malawska B <1 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 185:111785, 2019 : PubMed

            

    Title: Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives
    Jonczyk J, Lodarski K, Staszewski M, Godyn J, Zareba P, Soukup O, Janockova J, Korabecny J, Salat K and Bajda M <6 more author(s)>
    Ref: Bioorg Chem, 90:103084, 2019 : PubMed

            

    Title: New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition
    Malek R, Arribas RL, Palomino-Antolin A, Totoson P, Demougeot C, Kobrlova T, Soukup O, Iriepa I, Moraleda I and Ismaili L <12 more author(s)>
    Ref: Journal of Medicinal Chemistry, 62:11416, 2019 : PubMed

            

    Title: 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease
    Wichur T, Wieckowska A, Wieckowski K, Godyn J, Jonczyk J, Valdivieso ADR, Panek D, Pasieka A, Sabate R and Malawska B <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 187:111916, 2019 : PubMed

            

    Title: Novel carbamate derivatives as selective butyrylcholinesterase inhibitors
    Bajda M, Latka K, Hebda M, Jonczyk J, Malawska B
    Ref: Bioorg Chem, 78:29, 2018 : PubMed

            

    Title: Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents
    Panek D, Wieckowska A, Pasieka A, Godyn J, Jonczyk J, Bajda M, Knez D, Gobec S, Malawska B
    Ref: Molecules, 23:, 2018 : PubMed

            

    Title: Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents
    Panek D, Wieckowska A, Jonczyk J, Godyn J, Bajda M, Wichur T, Pasieka A, Knez D, Pislar A and Malawska B <6 more author(s)>
    Ref: ACS Chem Neurosci, 9:1074, 2018 : PubMed

            

    Title: Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease
    Wieckowska A, Wichur T, Godyn J, Bucki A, Marcinkowska M, Siwek A, Wieckowski K, Zareba P, Knez D and Malawska B <10 more author(s)>
    Ref: ACS Chem Neurosci, 9:1195, 2018 : PubMed

            

    Title: Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment
    Czarnecka K, Szymanski P, Girek M, Mikiciuk-Olasik E, Skibinski R, Kabzinski J, Majsterek I, Malawska B, Jonczyk J, Bajda M
    Ref: Bioorg Chem, 72:315, 2017 : PubMed

            

    Title: Lipophilic properties of anti-Alzheimer's agents determined by micellar electrokinetic chromatography and reversed-phase thin-layer chromatography
    Godyn J, Hebda M, Wieckowska A, Wieckowski K, Malawska B, Bajda M
    Ref: Electrophoresis, 38:1268, 2017 : PubMed

            

    Title: Advances toward multifunctional cholinesterase and beta-amyloid aggregation inhibitors
    Panek D, Wichur T, Godyn J, Pasieka A, Malawska B
    Ref: Future Med Chem, 9:1835, 2017 : PubMed

            

    Title: Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease
    Dgachi Y, Bautista-Aguilera OM, Benchekroun M, Martin H, Bonet A, Knez D, Godyn J, Malawska B, Gobec S and Ismaili L <5 more author(s)>
    Ref: Molecules, 21:, 2016 : PubMed

            

    Title: Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Abeta1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy
    Dgachi Y, Ismaili L, Knez D, Benchekroun M, Martin H, Szalaj N, Wehle S, Bautista-Aguilera OM, Luzet V and Marco-Contelles J <6 more author(s)>
    Ref: ChemMedChem, 11:1318, 2016 : PubMed

            

    Title: Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy
    Dgachi Y, Sokolov O, Luzet V, Godyn J, Panek D, Bonet A, Martin H, Iriepa I, Moraleda I and Ismaili L <7 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 126:576, 2016 : PubMed

            

    Title: Therapeutic strategies for Alzheimer's disease in clinical trials
    Godyn J, Jonczyk J, Panek D, Malawska B
    Ref: Pharmacol Rep, 68:127, 2016 : PubMed

            

    Title: Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta
    Hebda M, Bajda M, Wieckowska A, Szalaj N, Pasieka A, Panek D, Godyn J, Wichur T, Knez D and Malawska B <1 more author(s)>
    Ref: Molecules, 21:, 2016 : PubMed

            

    Title: Development of an in-vivo active reversible butyrylcholinesterase inhibitor
    Kosak U, Brus B, Knez D, Sink R, Zakelj S, Trontelj J, Pislar A, Slenc J, Gobec M and Gobec S <15 more author(s)>
    Ref: Sci Rep, 6:39495, 2016 : PubMed

            

    Title: Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands
    Lazewska D, Jonczyk J, Bajda M, Szalaj N, Wieckowska A, Panek D, Moore C, Kuder K, Malawska B, Kiec-Kononowicz K
    Ref: Bioorganic & Medicinal Chemistry Lett, 26:4140, 2016 : PubMed

            

    Title: Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation
    Panek D, Wieckowska A, Wichur T, Bajda M, Godyn J, Jonczyk J, Mika K, Janockova J, Soukup O and Malawska B <3 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 125:676, 2016 : PubMed

            

    Title: Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation
    Wieckowska A, Kolaczkowski M, Bucki A, Godyn J, Marcinkowska M, Wieckowski K, Zareba P, Siwek A, Kazek G and Malawska B <7 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 124:63, 2016 : PubMed

            

    Title: Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease
    Bajda M, Jonczyk J, Malawska B, Czarnecka K, Girek M, Olszewska P, Sikora J, Mikiciuk-Olasik E, Skibinski R and Szymanski P <1 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 23:5610, 2015 : PubMed

            

    Title: SEARCH FOR POTENTIAL CHOLINESTERASE INHIBITORS FROM THE ZINC DATABASE BY VIRTUAL SCREENING METHOD
    Bajda M, Panek D, Hebda M, Wieckowska A, Guzior N, Malawska B
    Ref: Acta Pol Pharm, 72:737, 2015 : PubMed

            

    Title: Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and beta-amyloid aggregation inhibitors with neuroprotective properties
    Guzior N, Bajda M, Skrok M, Kurpiewska K, Lewinski K, Brus B, Pislar A, Kos J, Gobec S, Malawska B
    Ref: Eur Journal of Medicinal Chemistry, 92C:738, 2015 : PubMed

            

    Title: Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease
    Guzior N, Wieckowska A, Panek D, Malawska B
    Ref: Curr Med Chem, 22:373, 2015 : PubMed

            

    Title: Isoindoline-1,3-dione derivatives targeting cholinesterases: Design, synthesis and biological evaluation of potential anti-Alzheimer's agents
    Guzior N, Bajda M, Rakoczy J, Brus B, Gobec S, Malawska B
    Ref: Bioorganic & Medicinal Chemistry, 23:1629, 2015 : PubMed

            

    Title: Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines
    Lodarski K, Jonczyk J, Guzior N, Bajda M, Gladysz J, Walczyk J, Jelen M, Morak-Mlodawska B, Pluta K, Malawska B
    Ref: J Enzyme Inhib Med Chem, 30:98, 2015 : PubMed

            

    Title: Multiple Ligands Targeting Cholinesterases and beta-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore
    Szalaj N, Bajda M, Dudek K, Brus B, Gobec S, Malawska B
    Ref: Arch Pharm (Weinheim), 348:556, 2015 : PubMed

            

    Title: Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with beta-amyloid anti-aggregation properties and beneficial effects on memory in vivo
    Wieckowska A, Wieckowski K, Bajda M, Brus B, Salat K, Czerwinska P, Gobec S, Filipek B, Malawska B
    Ref: Bioorganic & Medicinal Chemistry, 23:2445, 2015 : PubMed

            

    Title: Structure-based search for new inhibitors of cholinesterases
    Bajda M, Wieckowska A, Hebda M, Guzior N, Sotriffer CA, Malawska B
    Ref: Int J Mol Sci, 14:5608, 2013 : PubMed

            

    Title: New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis
    Szymanski P, Skibinski R, Inglot T, Bajda M, Jonczyk J, Malawska B, Mikiciuk-Olasik E
    Ref: Molecules, 18:2878, 2013 : PubMed

            

    Title: Design, synthesis and evaluation of novel 2-(aminoalkyl)-isoindoline-1,3-dione derivatives as dual-binding site acetylcholinesterase inhibitors
    Ignasik M, Bajda M, Guzior N, Prinz M, Holzgrabe U, Malawska B
    Ref: Arch Pharm (Weinheim), 345:509, 2012 : PubMed

            

    Title: Synthesis, biological activity and molecular modeling of 4-fluoro-N-[omega-(1,2,3,4-tetrahydroacridin-9-ylamino)-alkyl]-benzamide derivatives as cholinesterase inhibitors
    Szymanski P, Markowicz M, Bajda M, Malawska B, Mikiciuk-Olasik E
    Ref: Arzneimittelforschung, 62:655, 2012 : PubMed

            

    Title: 2,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution
    Szymanski P, Laznickova A, Laznicek M, Bajda M, Malawska B, Markowicz M, Mikiciuk-Olasik E
    Ref: Int J Mol Sci, 13:10067, 2012 : PubMed

            

    Title: Multi-target-directed ligands in Alzheimer's disease treatment
    Bajda M, Guzior N, Ignasik M, Malawska B
    Ref: Curr Med Chem, 18:4949, 2011 : PubMed

            

    Title: Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors
    Wieckowska A, Bajda M, Guzior N, Malawska B
    Ref: Eur Journal of Medicinal Chemistry, 45:5602, 2010 : PubMed

            

    Title: Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors
    Bajda M, Wieckowska A, Malawska B
    Ref: Acta Pol Pharm, 66:357, 2009 : PubMed

            

    Title: Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment
    Musial A, Bajda M, Malawska B
    Ref: Curr Med Chem, 14:2654, 2007 : PubMed

            

    Title: Synthesis of novel N-alkyl carbamates of a-substituted amides of g-hydroxybutyric acid as potential acetylcholinesterase inhibitors
    Musial A, Malawska B
    Ref: Acta Pol Pharm, 61 Suppl:94, 2004 : PubMed

            


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