Acetyl-esterase_deacetylase

Relationship

Family: Acetyl-esterase_deacetylase

Block: X

Parent Family: No family

Comment

PF05448 AXE1 Acetyl xylan esterase (EC 3.1.1.72) and cephalosporin c deacetylase (EC 3.1.1.41). This domain can be found in several bacterial acetyl xylan esterase proteins. Acetyl xylan esterases are enzymes that hydrolyse the ester linkages of the acetyl groups in position 2 and/or 3 of the xylose moieties of natural acetylated xylan from hardwood. These enzymes are one of the accessory enzymes which are part of the xylanolytic system, together with xylanases, beta-xylosidases, alpha-arabinofuranosidases and methylglucuronidases; these are all required for the complete hydrolysis of xylan Some sequences were previously in the Bacterial_lipase family (thema-TM0077...). Members of the family were associated with IPR000734, the esterase and lipase active site serine. This family contains the carbohydrate esterase family seven (CE-7) see the CAZy (Carbohydrate-Active enZYmes server ) (CE_7)

Database

Interpro : IPR008391 AXE1_dom , IPR039069 Carbohydrate esterase 7 family CE7

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : PF05448 AXE1

Prints : No Print

EC Number : 3.1.1.72 || 3.1.1.41

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (21)

Genes Proteins in Acetyl-esterase_deacetylase family (291)

Fragments of genes in Acetyl-esterase_deacetylase family (11)

Structures in Acetyl-esterase_deacetylase family (21)

Substrates in Acetyl-esterase_deacetylase family (9)

Inhibitors in Acetyl-esterase_deacetylase family (2)

References (6)

Title : Crystal structure and functional characterization of a cold-active acetyl xylan esterase (PbAcE) from psychrophilic soil microbe Paenibacillus sp - Park_2018_PLoS.One_13_e0206260
Author(s) : Park SH , Yoo W , Lee CW , Jeong CS , Shin SC , Kim HW , Park H , Kim KK , Kim TD , Lee JH
Ref : PLoS ONE , 13 :e0206260 , 2018
PubMedID: 30379876
Gene_locus related to this paper: 9mico-6AGQ

Title : Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima - Levisson_2012_Proteins_80_1545
Author(s) : Levisson M , Han GW , Deller MC , Xu Q , Biely P , Hendriks S , Ten Eyck LF , Flensburg C , Roversi P , Miller MD , McMullan D , von Delft F , Kreusch A , Deacon AM , Van der Oost J , Lesley SA , Elsliger MA , Kengen SW , Wilson IA
Ref : Proteins , 80 :1545 , 2012
PubMedID: 22411095
Gene_locus related to this paper: thema-TM0077

Title : Biochemical characterization and relative expression levels of multiple carbohydrate esterases of the xylanolytic rumen bacterium Prevotella ruminicola 23 grown on an ester-enriched substrate - Kabel_2011_Appl.Environ.Microbiol_77_5671
Author(s) : Kabel MA , Yeoman CJ , Han Y , Dodd D , Abbas CA , de Bont JA , Morrison M , Cann IK , Mackie RI
Ref : Applied Environmental Microbiology , 77 :5671 , 2011
PubMedID: 21742923
Gene_locus related to this paper: prer2-axea1 , prer2-axfa

Title : The crystal structure of the cephalosporin deacetylating enzyme acetyl xylan esterase bound to paraoxon explains the low sensitivity of this serine hydrolase to organophosphate inactivation - Montoro-Garcia_2011_Biochem.J_436_321
Author(s) : Montoro-Garcia S , Gil-Ortiz F , Garcia-Carmona F , Polo LM , Rubio V , Sanchez-Ferrer A
Ref : Biochemical Journal , 436 :321 , 2011
PubMedID: 21382014
Gene_locus related to this paper: bacpu-AXE

Title : Multifunctional Xylooligosaccharide\/Cephalosporin C Deacetylase Revealed by the Hexameric Structure of the Bacillus subtilis Enzyme at 1.9A Resolution - Vincent_2003_J.Mol.Biol_330_593
Author(s) : Vincent F , Charnock SJ , Verschueren KH , Turkenburg JP , Scott DJ , Offen WA , Roberts S , Pell G , Gilbert HJ , Davies GJ , Brannigan JA
Ref : Journal of Molecular Biology , 330 :593 , 2003
PubMedID: 12842474
Gene_locus related to this paper: bacsu-CAH

Title : The acetyl xylan esterase of Bacillus pumilus belongs to a family of esterases with broad substrate specificity - Degrassi_2000_Microbiology_146 ( Pt 7)_1585
Author(s) : Degrassi G , Kojic M , Ljubijankic G , Venturi V
Ref : Microbiology , 146 ( Pt 7) :1585 , 2000
PubMedID: 10878123
Gene_locus related to this paper: bacpu-AXE