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Author Report for: Takahashi M

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    Title: Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase
    Takahashi M, Hirota I, Nakano T, Kotani T, Takani D, Shiratori K, Choi Y, Haba M, Hosokawa M
    Ref: Drug Metab Pharmacokinet, 38:100391, 2021 : PubMed

            

    Title: Investigation of the chiral recognition ability of human carboxylesterase 1 using indomethacin esters
    Takahashi M, Takani D, Haba M, Hosokawa M
    Ref: Chirality, 32:73, 2020 : PubMed

            

    Title: Design, synthesis and biological evaluation of water-soluble phenytoin prodrugs considering the substrate recognition ability of human carboxylesterase 1
    Takahashi M, Lee YJ, Kanayama T, Kondo Y, Nishio K, Mukai K, Haba M, Hosokawa M
    Ref: Eur J Pharm Sci, :105455, 2020 : PubMed

            

    Title: Structure-activity relationship of atorvastatin derivatives for metabolic activation by hydrolases
    Mizoi K, Takahashi M, Sakai S, Ogihara T, Haba M, Hosokawa M
    Ref: Xenobiotica, :1, 2019 : PubMed

            

    Title: rCBF and cognitive impairment changes assessed by SPECT and ADAS-cog in late-onset Alzheimer's disease after 18 months of treatment with the cholinesterase inhibitors donepezil or galantamine
    Shirayama Y, Takahashi M, Oda Y, Yoshino K, Sato K, Okubo T, Iyo M
    Ref: Brain Imaging Behav, 13:75, 2019 : PubMed

            

    Title: Synthesis and evaluation of haloperidol ester prodrugs metabolically activated by human carboxylesterase
    Takahashi M, Uehara T, Nonaka M, Minagawa Y, Yamazaki R, Haba M, Hosokawa M
    Ref: Eur J Pharm Sci, 132:125, 2019 : PubMed

            

    Title: Efficacy, Safety, and Tolerability of Switching from Oral Cholinesterase Inhibitors to Rivastigmine Transdermal Patch with 1-Step Titration in Patients with Mild to Moderate Alzheimer's Disease: A 24-Week, Open-Label, Multicenter Study in Japan
    Ueda K, Katayama S, Arai T, Furuta N, Ikebe S, Ishida Y, Kanaya K, Ouma S, Sakurai H and Nakamura Y <9 more author(s)>
    Ref: Dement Geriatr Cogn Dis Extra, 9:302, 2019 : PubMed

            

    Title: Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells
    Yamazaki H, Takahashi M, Wakabayashi T, Sakai K, Yamamuro D, Takei A, Takei S, Nagashima S, Yagyu H and Ishibashi S <2 more author(s)>
    Ref: J Atheroscler Thromb, 26:246, 2019 : PubMed

            

    Title: Chemical synthesis of an indomethacin ester prodrug and its metabolic activation by human carboxylesterase 1
    Takahashi M, Ogawa T, Kashiwagi H, Fukushima F, Yoshitsugu M, Haba M, Hosokawa M
    Ref: Bioorganic & Medicinal Chemistry Lett, 28:997, 2018 : PubMed

            

    Title: Relationships between cognitive impairment on ADAS-cog and regional cerebral blood flow using SPECT in late-onset Alzheimer's disease
    Takahashi M, Oda Y, Okubo T, Shirayama Y
    Ref: J Neural Transm (Vienna), 124:1109, 2017 : PubMed

            

    Title: Anagliptin, a dipeptidyl peptidase-4 inhibitor, decreases macrophage infiltration and suppresses atherosclerosis in aortic and coronary arteries in cholesterol-fed rabbits
    Hirano T, Yamashita S, Takahashi M, Hashimoto H, Mori Y, Goto M
    Ref: Metabolism, 65:893, 2016 : PubMed

            

    Title: Edrophonium Challenge Test for Blepharospasm
    Matsumoto S, Murakami N, Koizumi H, Takahashi M, Izumi Y, Kaji R
    Ref: Front Neurosci, 10:226, 2016 : PubMed

            

    Title: Quantification of plasma exosome is a potential prognostic marker for esophageal squamous cell carcinoma
    Matsumoto Y, Kano M, Akutsu Y, Hanari N, Hoshino I, Murakami K, Usui A, Suito H, Takahashi M and Matsubara H <4 more author(s)>
    Ref: Oncol Rep, 36:2535, 2016 : PubMed

            

    Title: Synthesis and evaluation of atorvastatin esters as prodrugs metabolically activated by human carboxylesterases
    Mizoi K, Takahashi M, Haba M, Hosokawa M
    Ref: Bioorganic & Medicinal Chemistry Lett, 26:921, 2016 : PubMed

            

    Title: The prediction of response to Galantamine treatment in Patients with mild to moderate Alzheimer's Disease
    Ohnishi T, Sakiyama Y, Okuri Y, Kimura Y, Sugiyama N, Saito T, Takahashi M, Kobayashi T
    Ref: Curr Alzheimer Res, 11:110, 2014 : PubMed

            

    Title: Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages
    Sakai K, Igarashi M, Yamamuro D, Ohshiro T, Nagashima S, Takahashi M, Enkhtuvshin B, Sekiya M, Okazaki H and Ishibashi S <1 more author(s)>
    Ref: J Lipid Res, 55:2033, 2014 : PubMed

            

    Title: Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages
    Sekiya M, Yamamuro D, Ohshiro T, Honda A, Takahashi M, Kumagai M, Sakai K, Nagashima S, Tomoda H and Ishibashi S <4 more author(s)>
    Ref: J Lipid Res, 55:2082, 2014 : PubMed

            

    Title: Macrophage lipoprotein lipase modulates the development of atherosclerosis but not adiposity
    Takahashi M, Yagyu H, Tazoe F, Nagashima S, Ohshiro T, Okada K, Osuga J, Goldberg IJ, Ishibashi S
    Ref: J Lipid Res, 54:1124, 2013 : PubMed

            

    Title: Complete genome sequence of Sphingobium sp. strain SYK-6, a degrader of lignin-derived biaryls and monoaryls
    Masai E, Kamimura N, Kasai D, Oguchi A, Ankai A, Fukui S, Takahashi M, Yashiro I, Sasaki H and Fujita N <9 more author(s)>
    Ref: Journal of Bacteriology, 194:534, 2012 : PubMed

            

    Title: Corynebacterium ulcerans 0102 carries the gene encoding diphtheria toxin on a prophage different from the C. diphtheriae NCTC 13129 prophage
    Sekizuka T, Yamamoto A, Komiya T, Kenri T, Takeuchi F, Shibayama K, Takahashi M, Kuroda M, Iwaki M
    Ref: BMC Microbiol, 12:72, 2012 : PubMed

            

    Title: Complete genome sequences of rat and mouse segmented filamentous bacteria, a potent inducer of th17 cell differentiation
    Prakash T, Oshima K, Morita H, Fukuda S, Imaoka A, Kumar N, Sharma VK, Kim SW, Takahashi M and Hattori M <4 more author(s)>
    Ref: Cell Host Microbe, 10:273, 2011 : PubMed

            

    Title: [Acute respiratory failure associated with cholinergic crisis: report of five cases and review of the literature]
    Takahashi M, Ubukata S, Sato E, Shoji M, Morikawa N, Watanabe H, Takahashi H
    Ref: Nihon Kokyuki Gakkai Zasshi, 49:877, 2011 : PubMed

            

    Title: Molecular analysis of a novel LCAT mutation (Gly179 --> Arg) found in a patient with complete LCAT deficiency
    Wang XL, Osuga J, Tazoe F, Okada K, Nagashima S, Takahashi M, Ohshiro T, Bayasgalan T, Yagyu H, Ishibashi S
    Ref: J Atheroscler Thromb, 18:713, 2011 : PubMed

            

    Title: The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages
    Igarashi M, Osuga J, Uozaki H, Sekiya M, Nagashima S, Takahashi M, Takase S, Takanashi M, Li Y and Ishibashi S <11 more author(s)>
    Ref: Circulation Research, 107:1387, 2010 : PubMed

            

    Title: Association of the HSPG2 gene with neuroleptic-induced tardive dyskinesia
    Syu A, Ishiguro H, Inada T, Horiuchi Y, Tanaka S, Ishikawa M, Arai M, Itokawa M, Niizato K and Arinami T <8 more author(s)>
    Ref: Neuropsychopharmacology, 35:1155, 2010 : PubMed

            

    Title: CS-8958, a prodrug of the novel neuraminidase inhibitor R-125489, demonstrates a favorable long-retention profile in the mouse respiratory tract
    Koyama K, Takahashi M, Oitate M, Nakai N, Takakusa H, Miura S, Okazaki O
    Ref: Antimicrobial Agents & Chemotherapy, 53:4845, 2009 : PubMed

            

    Title: Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis
    Sekiya M, Osuga J, Nagashima S, Ohshiro T, Igarashi M, Okazaki H, Takahashi M, Tazoe F, Wada T and Ishibashi S <11 more author(s)>
    Ref: Cell Metab, 10:219, 2009 : PubMed

            

    Title: Effects of hormone-sensitive lipase disruption on cardiac energy metabolism in response to fasting and refeeding
    Suzuki J, Ueno M, Uno M, Hirose Y, Zenimaru Y, Takahashi S, Osuga J, Ishibashi S, Takahashi M and Miyamori I <3 more author(s)>
    Ref: American Journal of Physiology Endocrinol Metab, 297:E1115, 2009 : PubMed

            

    Title: Synthesis and structure-activity relationships of potent 1-(2-substituted-aminoacetyl)-4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
    Fukushima H, Hiratate A, Takahashi M, Saito-Hori M, Munetomo E, Kitano K, Saito H, Takaoka Y, Yamamoto K
    Ref: Chem Pharm Bull (Tokyo), 56:1110, 2008 : PubMed

            

    Title: Synthesis and structure-activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
    Fukushima H, Hiratate A, Takahashi M, Mikami A, Saito-Hori M, Munetomo E, Kitano K, Chonan S, Saito H and Yamamoto K <2 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry, 16:4093, 2008 : PubMed

            

    Title: Effect of the angiotensin II receptor antagonist telmisartan on lipoprotein lipase mass in preheparin serum
    Hitsumoto T, Takahashi M, Iizuka T, Shirai K
    Ref: J Atheroscler Thromb, 15:138, 2008 : PubMed

            

    Title: Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning
    Liu Y, Padgett D, Takahashi M, Li H, Sayeed A, Teichert RW, Olivera BM, McArdle JJ, Green WN, Lin W
    Ref: Development, 135:1957, 2008 : PubMed

            

    Title: In vivo arterial lipoprotein lipase expression augments inflammatory responses and impairs vascular dilatation
    Takahashi M, Hiyama Y, Yokoyama M, Yu S, Hu Y, Melford K, Bensadoun A, Goldberg IJ
    Ref: Arterioscler Thromb Vasc Biol, 28:455, 2008 : PubMed

            

    Title: Unwarranted administration of acetylcholinesterase inhibitors can impair genioglossus and diaphragm muscle function
    Eikermann M, Fassbender P, Malhotra A, Takahashi M, Kubo S, Jordan AS, Gautam S, White DP, Chamberlin NL
    Ref: Anesthesiology, 107:621, 2007 : PubMed

            

    Title: Structure and allele-specific expression variation of novel alpha/beta hydrolase fold proteins in gentian plants
    Hikage T, Saitoh Y, Tanaka-Saito C, Hagami H, Satou F, Shimotai Y, Nakano Y, Takahashi M, Takahata Y, Tsutsumi K
    Ref: Mol Genet Genomics, 278:95, 2007 : PubMed

            

    Title: Tissue-specific regulation of juvenile hormone esterase gene expression by 20-hydroxyecdysone and juvenile hormone in Bombyx mori
    Kamimura M, Takahashi M, Kikuchi K, Reza AM, Kiuchi M
    Ref: Archives of Insect Biochemistry & Physiology, 65:143, 2007 : PubMed

            

    Title: Genome sequencing and analysis of Aspergillus oryzae
    Machida M, Asai K, Sano M, Tanaka T, Kumagai T, Terai G, Kusumoto K, Arima T, Akita O and Kikuchi H <54 more author(s)>
    Ref: Nature, 438:1157, 2005 : PubMed

            

    Title: Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity in Min mice
    Niho N, Mutoh M, Takahashi M, Tsutsumi K, Sugimura T, Wakabayashi K
    Ref: Proc Natl Acad Sci U S A, 102:2970, 2005 : PubMed

            

    Title: Mest/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size
    Takahashi M, Kamei Y, Ezaki O
    Ref: American Journal of Physiology Endocrinol Metab, 288:E117, 2005 : PubMed

            

    Title: Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species
    Takeuchi F, Watanabe S, Baba T, Yuzawa H, Ito T, Morimoto Y, Kuroda M, Cui L, Takahashi M and Hiramatsu K <4 more author(s)>
    Ref: Journal of Bacteriology, 187:7292, 2005 : PubMed

            

    Title: Complete sequencing and characterization of 21,243 full-length human cDNAs
    Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H and Sugano S <144 more author(s)>
    Ref: Nat Genet, 36:40, 2004 : PubMed

            

    Title: Novel LPL mutation (L303F) found in a patient associated with coronary artery disease and severe systemic atherosclerosis
    Saika Y, Sakai N, Takahashi M, Maruyama T, Kihara S, Ouchi N, Ishigami M, Hiraoka H, Nakamura T and Matsuzawa Y <1 more author(s)>
    Ref: European Journal of Clinical Investigation, 33:216, 2003 : PubMed

            

    Title: A novel type hypertriglyceridemia observed in FLS mice
    Takahashi M, Saibara T, Nemoto Y, Ono M, Akisawa N, Iwasaki S, Toda K, Ogawa Y, Wakatsuki A and Onishi S <1 more author(s)>
    Ref: Lipids, 38:687, 2003 : PubMed

            

    Title: Overexpression and functional characterization of a serine carboxypeptidase inhibitor (I(C)) from Saccharomyces cerevisiae
    Mima J, Suzuki H, Takahashi M, Hayashi R
    Ref: J Biochem, 132:967, 2002 : PubMed

            

    Title: An amino acid residue whose change by mutation affects drug binding to the HERG channel
    Ishii K, Kondo K, Takahashi M, Kimura M, Endoh M
    Ref: FEBS Letters, 506:191, 2001 : PubMed

            

    Title: Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7
    Kawarabayasi Y, Hino Y, Horikawa H, Jin-no K, Takahashi M, Sekine M, Baba S, Ankai A, Kosugi H and Kikuchi H <20 more author(s)>
    Ref: DNA Research, 8:123, 2001 : PubMed

            

    Title: Acquisition of neuronal proteins during differentiation of NG108-15 cells
    Tojima T, Yamane Y, Takahashi M, Ito E
    Ref: Neurosci Res, 37:153, 2000 : PubMed

            

    Title: Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1
    Kawarabayasi Y, Hino Y, Horikawa H, Yamazaki S, Haikawa Y, Jin-no K, Takahashi M, Sekine M, Baba S and Kikuchi H <20 more author(s)>
    Ref: DNA Research, 6:83, 1999 : PubMed

            

    Title: Immunohistochemistry with an antibody to human liver carboxylesterase in human brain tissues
    Yamada T, Hosokawa M, Satoh T, Moroo I, Takahashi M, Akatsu H, Yamamoto T
    Ref: Brain Research, 658:163, 1994 : PubMed

            

    Title: Influence of the acute stress on agonist-stimulated phosphoinositide hydrolysis in the rat cerebral cortex
    Morinobu S, Kuwayama N, Kawanami T, Okuyama N, Takahashi M, Totsuka S, Endoh M
    Ref: Prog Neuropsychopharmacol Biological Psychiatry, 16:561, 1992 : PubMed

            

    Title: Molecular properties of dihydropyridine-sensitive calcium channels
    Catterall WA, Seagar MJ, Takahashi M, Nunoki K
    Ref: Annals of the New York Academy of Sciences, 560:1, 1989 : PubMed

            

    Title: Molecular properties of dihydropyridine-sensitive calcium channels
    Seagar MJ, Takahashi M, Catterall WA
    Ref: Annals of the New York Academy of Sciences, 522:162, 1988 : PubMed

            

    Title: Identification of an alpha subunit of dihydropyridine-sensitive brain calcium channels
    Takahashi M, Catterall WA
    Ref: Science, 236:88, 1987 : PubMed

            

    Title: Prolonged neuromuscular blockade following trimetaphan infusion. A case report and in vitro study of cholinesterase inhibition
    Nakamura K, Koide M, Imanaga T, Ogasawara H, Takahashi M, Yoshikawa M
    Ref: Anaesthesia, 35:1202, 1980 : PubMed

            

    Title: Localized beta-galactosidase deficiency. Occurrence in cerebellar ataxia with myoclonus epilepsy and macular cherry-red spot--a new variant of GM1-gangliosidosis?
    Yamamoto A, Adachi S, Kawamura S, Takahashi M, Kitani T
    Ref: Archives of Internal Medicine, 134:627, 1974 : PubMed

            


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