2000

Aurilia_2000_Microbiology_146_1391 Three multidomain esterases from the cellulolytic rumen anaerobe Ruminococcus flavefaciens 17 that carry divergent dockerin sequences.
Heidelberg_2000_Nature_406_477 DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
Giraud_2000_Proc.Natl.Acad.Sci.U.S.A_97_14795 Effect of Bradyrhizobium photosynthesis on stem nodulation of Aeschynomene sensitiva
Kataoka_2000_Eur.J.Biochem_267_3 3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46
Jones_2000_J.Bacteriol_182_2018 sal genes determining the catabolism of salicylate esters are part of a supraoperonic cluster of catabolic genes in Acinetobacter sp. strain ADP1
Cheng_2000_J.Bacteriol_182_4744 Genetic analysis of a gene cluster for cyclohexanol oxidation in Acinetobacter sp. Strain SE19 by in vitro transposition
Suzuki_2000_Gene_242_331 Complete nucleotide sequence of a plant tumor-inducing Ti plasmid.
Schrammeijer_2000_J.Exp.Bot_51_1167 Sequence analysis of the vir-region from Agrobacterium tumefaciens octopine Ti plasmid pTi15955
Matthysse_2000_Biochim.Biophys.Acta_1490_208 A region of the Agrobacterium tumefaciens chromosome containing genes required for virulence and attachment to host cells
Song_2000_Biomacromolecules_1_433 In vitro polymerization and copolymerization of 3-hydroxypropionyl-CoA with the PHB synthase from Ralstonia eutropha
Bourne_2000_Structure.Fold.Des_8_143 The atomic-resolution structure of a novel bacterial esterase
De Simone_2000_J.Mol.Biol_303_761 A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase
D'Auria_2000_Proteins_40_473 The esterase from the thermophilic eubacterium Bacillus acidocaldarius: structural-functional relationship and comparison with the esterase from the hyperthermophilic archaeon Archaeoglobus fulgidus
Bawden_2000_Virology_274_120 Complete Genomic Sequence of the Amsacta moorei Entomopoxvirus: Analysis and Comparison with Other Poxviruses.
Rouhiainen_2000_Mol.Microbiol_37_156 Genes encoding synthetases of cyclic depsipeptides, anabaenopeptilides, in Anabaena strain 90
Salanoubat_2000_Nature_408_820 Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana
Theologis_2000_Nature_408_816 Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana
Morisseau_2000_Arch.Biochem.Biophys_378_321 Cress and potato soluble epoxide hydrolases: purification, biochemical characterization, and comparison to mammalian enzymes
Sato_2000_DNA.Res_7_131 Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones
Tabata_2000_Nature_408_823 Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana
Sato_2000_DNA.Res_7_31 Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones
Kaneko_2000_DNA.Res_7_217 Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones
Lehfeldt_2000_Plant.Cell_12_1295 Cloning of the SNG1 gene of Arabidopsis reveals a role for a serine carboxypeptidase-like protein as an acyltransferase in secondary metabolism
Manco_2000_Protein.Eng_13_197 Homology modeling and identification of serine 160 as nucleophile of the active site in a thermostable carboxylesterase from the archaeon Archaeoglobus fulgidus
Betz_2000_J.Basic.Microbiol_40_7 Molecular cloning, sequencing, expression, and site-directed mutagenesis of the 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase gene from Arthrobacter spec. Ru61a
Yu_2000_Gene_248_157 Cloning and characterization of avfA and omtB genes involved in aflatoxin biosynthesis in three Aspergillus species
Pignede_2000_J.Bacteriol_182_2802 Characterization of an extracellular lipase encoded by LIP2 in yarrowia lipolytica
Zou_2000_Structure.Fold.Des_8_111 Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases
Toida_2000_FEMS.Microbiol.Lett_189_159 Cloning and sequencing of the triacylglycerol lipase gene of Aspergillus oryzae and its expression in Escherichia coli
Segura_2000_Gene_260_113 Beta-ketothiolase genes in Azotobacter vinelandii
Imamura_2000_J.Biochem_127_419 Purification and characterization of a monoacylglycerol lipase from the moderately thermophilic Bacillus sp. H-257
Weber_2000_Structure_8_407 Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases
Takami_2000_Nucleic.Acids.Res_28_4317 Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis
Degrassi_2000_Microbiology_146 ( Pt 7)_1585 The acetyl xylan esterase of Bacillus pumilus belongs to a family of esterases with broad substrate specificity
Prim_2000_Res.Microbiol_151_303 estA, a gene coding for a cell-bound esterase from Paenibacillus sp. BP-23, is a new member of the bacterial subclass of type B carboxylesterases
Eggert_2000_Eur.J.Biochem_267_6459 A novel extracellular esterase from Bacillus subtilis and its conversion to a monoacylglycerol hydrolase
Vijay_2000_Mol.Microbiol_35_180 A PP2C phosphatase containing a PAS domain is required to convey signals of energy stress to the sigmaB transcription factor of Bacillus subtilis
Beja_2000_Science_289_1902 Bacterial rhodopsin: evidence for a new type of phototrophy in the sea
Henne_2000_Appl.Environ.Microbiol_66_3113 Screening of environmental DNA libraries for the presence of genes conferring lipolytic activity on Escherichia coli
Duffner_2000_Gene_256_215 Phenol\/cresol degradation by the thermophilic Bacillus thermoglucosidasius A7: cloning and sequence analysis of five genes involved in the pathway
Hernandez_2000_Insect.Biochem.Mol.Biol_30_969 Identification of a point mutation in an esterase gene in different populations of the southern cattle tick, Boophilus microplus
Jamroz_2000_J.Insect.Physiol_46_685 Molecular and biochemical survey of acaricide resistance mechanisms in larvae from Mexican strains of the southern cattle tick, Boophilus microplus
MacPhee_2000_Biochemistry_39_3433 Apolipoprotein C-II39-62 activates lipoprotein lipase by direct lipid-independent binding
Bellizzi_2000_Proc.Natl.Acad.Sci.U.S.A_97_4573 The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis
Das_2000_J.Biol.Chem_275_23847 Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride
Reiter_2000_Appl.Microbiol.Biotechnol_54_778 Cloning and characterization of EstC from Burkholderia gladioli, a novel-type esterase related to plant enzymes
Rodrigues_2000_Appl.Microbiol.Biotechnol_53_453 Polyhydroxyalkanoate accumulation in Burkholderia sp.: a molecular approach to elucidate the genes involved in the formation of two homopolymers consisting of short-chain-length 3-hydroxyalkanoic acids
Seah_2000_J.Biol.Chem_275_15701 Identification of a serine hydrolase as a key determinant in the microbial degradation of polychlorinated biphenyls
Combes_2000_J.Mol.Biol_300_727 Four genes encode acetylcholinesterases in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. cDNA sequences, genomic structures, mutations and in vivo expression
Takeda_2000_J.Biosci.Bioeng_90_416 Cloning and expression of the gene encoding thermostable poly(3-hydroxybutyrate) depolymerase.
Parkhill_2000_Nature_403_665 The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences
Hube_2000_Arch.Microbiol_174_362 Secreted lipases of Candida albicans: cloning, characterisation and expression analysis of a new gene family with at least ten members
Samukawa_2000_J.Biosci.Bioeng_90_180 Pretreatment of immobilized Candida antarctica lipase for biodiesel fuel production from plant oil
Robinson-Rechavi_2000_Mol.Biol.Evol_17_1410 Nuclear gene LCAT supports rodent monophyly.
Michaux_2000_Mol.Phylogenet.Evol_17_280 The Bushlike Radiation of Muroid Rodents Is Exemplified by the Molecular Phylogeny of the LCAT Nuclear Gene
Daub_2000_Annu.Rev.Phytopathol_38_461 The Photoactivated Cercospora Toxin Cercosporin: Contributions to Plant Disease and Fundamental Biology
Xiong_2000_Science_289_1724 Molecular evidence for the early evolution of photosynthesis
Read_2000_Nucleic.Acids.Res_28_1397 Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39
Shirai_2000_Nucleic.Acids.Res_28_2311 Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA
Farrow_2000_Antimicrob.Agents.Chemother_44_411 The macrolide-lincosamide-streptogramin B resistance determinant from Clostridium difficile 630 contains two erm(B) genes
Banu_2000_Mol.Microbiol_35_854 Identification of novel VirR\/VirS-regulated genes in Clostridium perfringens
Chen_2000_Virus.Res_66_155 Analysis of host response modifier ORFs of ectromelia virus, the causative agent of mousepox
Hong_2000_Proc.Natl.Acad.Sci.U.S.A_97_8717 An ethylene-induced cDNA encoding a lipase expressed at the onset of senescence.
Robin_2000_J.Mol.Evol_51_149 Reconstructing the diversification of alpha-esterases: comparing the gene clusters of Drosophila buzzatii and D. melanogaster
Oakeshott_2000_Genetica_110_231 An episode of accelerated amino acid change in Drosophila esterase-6 associated with a change in physiological function
Kliman_2000_Genetics_156_1913 The population genetics of the origin and divergence of the Drosophila simulans complex species
Adams_2000_Science_287_2185 The genome sequence of Drosophila melanogaster
Harel_2000_Protein.Sci_9_1063 Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors
Huang_2000_Genetics_156_1219 A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster
Fremion_2000_Embo.J_19_4463 Amalgam is a ligand for the transmembrane receptor neurotactin and is required for neurotactin-mediated cell adhesion and axon fasciculation in Drosophila
Rubin_2000_Science_287_2222 A Drosophila complementary DNA resource
Begun_2000_Proc.Natl.Acad.Sci.U.S.A_97_5960 Reduced X-linked nucleotide polymorphism in Drosophila simulans
Robin_2000_Mol.Biol.Evol_17_563 The Evolution of an alpha-Esterase Pseudogene Inactivated in the Drosophila melanogaster Lineage
Fleming_2000_Biochemistry_39_1522 Catalytic mechanism of a C-C hydrolase enzyme: evidence for a gem-diol intermediate, not an acyl enzyme
Grynberg_2000_Microbiology_146 ( Pt 10)_2695 The Aspergillus nidulans cysA gene encodes a novel type of serine O-acetyltransferase which is homologous to homoserine O-acetyltransferases
Bartels_2000_Biochem.Pharmacol_60_479 Determination of the DNA sequences of acetylcholinesterase and butyrylcholinesterase from cat and demonstration of the existence of both in cat plasma
Pouch_2000_Mol.Microbiol_35_368 Characterization of the 20S proteasome from the actinomycete Frankia
Brunner_2000_Chromosome.Res_8_465 Molecular cloning and characterization of the Fugu rubripes MEST\/COPG2 imprinting cluster and chromosomal localization in Fugu and Tetraodon nigroviridis
Cho_2000_FEMS.Microbiol.Lett_186_235 Cloning, sequencing and expression in Escherichia coli of a thermophilic lipase from Bacillus thermoleovorans ID-1
Born_2000_Biochemistry_39_8556 Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Haemophilus influenzae met2-encoded homoserine transacetylase
Langen_2000_Electrophoresis_21_411 Two-dimensional map of the proteome of Haemophilus influenzae
Guerrero_2000_Insect.Biochem.Mol.Biol_30_1107 Cloning of a horn fly cDNA, HialphaE7, encoding an esterase whose transcript concentration is elevated in diazinon-resistant flies
Ng_2000_Proc.Natl.Acad.Sci.U.S.A_97_12176 Genome sequence of Halobacterium species NRC-1
Wierdl_2000_Biochem.Pharmacol_59_773 Isolation and characterization of a cDNA encoding a horse liver butyrylcholinesterase: evidence for CPT-11 drug activation
Edgar_2000_J.Anat_197_320 LABH-1: cloning of a novel alpha\/beta hydrolase fold protein from mouse lung in Proceedings of the Anatomical Society of Great Britain and Ireland
Lai_2000_Genome.Res_10_703 Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics
Kryger_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1385 Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II
Jones_2000_Biochem.Biophys.Res.Commun_275_233 Identification of PTE2, a human peroxisomal long-chain acyl-CoA thioesterase.
Fujino_2000_Biochim.Biophys.Acta_1478_102 Identification of oxidized protein hydrolase of human erythrocytes as acylpeptide hydrolase
Terzyan_2000_Protein.Sci_9_1783 Crystal structure of the catalytic domain of human bile salt activated lipase
Bruneau_2000_J.Histochem.Cytochem_48_267 The affinity binding sites of pancreatic bile salt-dependent lipase in pancreatic and intestinal tissues
Ghosh_2000_Physiol.Genomics_2_1 Cholesteryl ester hydrolase in human monocyte\/macrophage: cloning, sequencing, and expression of full-length cDNA
Uphoff_2000_Leuk.Lymphoma_39_257 Biology of monocyte-specific esterase
Satoh_2000_Neurotoxicol_21_223 Organophosphates and their impact on the global environment
Padmanabhan_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1479 Purification, crystallization and preliminary X-ray crystallographic analysis of human CCG1-interacting factor B
Chiravuri_2000_J.Immunol_165_5695 Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase.
Abbott_2000_Eur.J.Biochem_267_6140 Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8
Nagase_2000_DNA.Res_7_143 Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro
Belmahdi_2000_Hum.Mutat_16_450 Identification of 6 new polymorphisms, g.11177G>A, g.14622C>T (R49C), g.17540T>C, g.17639T>C, g.30929T>C, g.31074G>A (R454Q), in the human microsomal epoxide hydrolase gene (EPHX1) in a French population
Sandberg_2000_J.Biol.Chem_275_28873 Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms
Hu_2000_Proc.Natl.Acad.Sci.U.S.A_97_9543 Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning
Nagase_2000_DNA.Res_7_65 Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro
Goldstein_2000_J.Biol.Chem_275_2554 Identification of an alternatively spliced seprase mRNA that encodes a novel intracellular isoform
Osuga_2000_Proc.Natl.Acad.Sci.U.S.A_97_787 Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
Hattori_2000_Nature_405_311 The DNA sequence of human chromosome 21
Bertolini_2000_Clin.Genet_57_140 Pseudodominance of lipoprotein lipase (LPL) deficiency due to a nonsense mutation (Tyr302>Term) in exon 6 of LPL gene in an Italian family from Sardinia (LPL(Olbia))
Devedjiev_2000_Structure_8_1137 Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A
Zhang_2000_Genome.Res_10_1546 Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem\/progenitor cells
Kosaki_2000_Am.J.Hum.Genet_66_309 Isoform-specific imprinting of the human PEG1\/MEST gene
Kalaydjieva_2000_Am.J.Hum.Genet_67_47 N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom
Guan_2000_Cancer.Res_60_749 Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer
Scheiffele_2000_Cell_101_657 Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
Philibert_2000_Gene_246_303 The structure and expression of the human neuroligin-3 gene
Kruse_2000_Am.J.Hum.Genet_66_1522 The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma
Yamada_2000_Atherosclerosis_150_209 Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population
Tolstykh_2000_Embo.J_19_5682 Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits
Cajal_2000_Biochimie_82_1053 Effect of the lipid interface on the catalytic activity and spectroscopic properties of a fungal lipase
Jutila_2000_Biophys.J_78_1634 Detergent-induced conformational changes of Humicola lanuginosa lipase studied by fluorescence spectroscopy
Cajal_2000_Biochemistry_39_413 Interfacial control of lid opening in Thermomyces lanuginosa lipase
Brzozowski_2000_Biochemistry_39_15071 Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase
Fernandez_2000_Appl.Environ.Microbiol_66_1360 Cloning, Characterization, Controlled Overexpression, and Inactivation of the Major Tributyrin Esterase Gene of Lactococcus lactis.
Koebmann_2000_J.Bacteriol_182_4738 The membrane bound H+-ATPase complex is essential for growth of Lactococcus lactis.
Varmanen_2000_J.Bacteriol_182_146 X-prolyl dipeptidyl aminopeptidase gene (pepX) is part of the glnRA operon in Lactobacillus rhamnosus
Thomas_2000_Int.J.Biol.Macromol_27_145 Endo-1,3\;1,4-beta-glucanase from coleoptiles of rice and maize: role in the regulation of plant growth
Lee_2000_Proc.Natl.Acad.Sci.U.S.A_97_6091 The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus
Tulman_2000_J.Virol_74_7980 The genome of a very virulent Marek's disease virus
Kaneko_2000_DNA.Res_7_331 Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti
Tillett_2000_Chem.Biol_7_753 Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-polyketide synthetase system
Volchegursky_2000_Mol.Microbiol_37_752 Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea
Wang_2000_Arch.Biochem.Biophys_382_31 Affinity purification and characterization of a cutinase from the fungal plant pathogen Monilinia fructicola (Wint.) honey
Carninci_2000_Genome.Res_10_1617 Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes
Shibata_2000_Genome.Res_10_1757 RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer
Inoue_2000_Biochem.Biophys.Res.Commun_268_553 Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains
Xie_2000_J.Pharmacol.Exp.Ther_293_896 Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase
Hunt_2000_Cell.Biochem.Biophys_32 Spring_317 Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism
Hartsfield_2000_Mamm.Genome_11_915 The Ephx1(d) allele encoding an Arg338Cys substitution is associated with heat lability
Ueno_2000_Genes.Cells_5_859 Involvement of fatty acid synthase in axonal development in mouse embryos
Dandekar_2000_Nucleic.Acids.Res_28_3278 Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames
Fan_2000_Xi.Bao.Yu.Fen.Zi.Mian.Yi.Xue.Za.Zhi_16_314 Cloning of Ag85B gene of Mycobacterium tuberculosis and its construction of eukaryotic expression vector.
Ronning_2000_Nat.Struct.Biol_7_141 Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines
De Voss_2000_Proc.Natl.Acad.Sci.U.S.A_97_1252 The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages
Stinear_2000_J.Bacteriol_182_6322 Comparative genetic analysis of Mycobacterium ulcerans and Mycobacterium marinum reveals evidence of recent divergence
Tettelin_2000_Science_287_1809 Complete genome sequence of Neisseria meningitidis serogroup B strain MC58
Parkhill_2000_Nature_404_502 Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491
Tomita_2000_Insect.Biochem.Mol.Biol_30_325 Absence of protein polymorphism attributable to insecticide-insensitivity of acetylcholinesterase in the green rice leafhopper, Nephotettix cincticeps
Small_2000_Insect.Mol.Biol_9_647 Molecular characterization of the amplified carboxylesterase gene associated with organophosphorus insecticide resistance in the brown planthopper, Nilaparvata lugens
Hussein_2000_Eur.J.Biochem_267_2276 Determinants of substrate specificity of a second non-neuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis
Blum_2000_J.Bacteriol_182_1346 Feruloyl esterase activity of the Clostridium thermocellum cellulosome can be attributed to previously unknown domains of XynY and XynZ
Hunt_2000_FEMS.Microbiol.Lett_192_249 Characterisation of a Pasteurella multocida esterase gene which confers a hemolytic phenotype in Escherichia coli under anaerobic conditions
Sun_2000_Virology_276_27 Characterization of a beta-1,3-glucanase encoded by chlorella virus PBCV-1
Kroon_2000_Eur.J.Biochem_267_6740 A modular esterase from Penicillium funiculosum which releases ferulic acid from plant cell walls and binds crystalline cellulose contains a carbohydrate binding module
Miyazaki_2000_J.Polym.Environ_8_175 Properties of a Poly(3-hydroxybutyrate) Depolymerase from Penicillium funiculosum
Kimata-Ariga_2000_EMBO.J_19_5041 Differential electron flow around photosystem I by two C(4)-photosynthetic-cell-specific ferredoxins
Kumagai_2000_Infect.Immun_68_716 Enzymatic properties of dipeptidyl aminopeptidase IV produced by the periodontal pathogen Porphyromonas gingivalis and its participation in virulence
Stover_2000_Nature_406_959 Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
Nardini_2000_J.Biol.Chem_275_31219 Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases
Lee_2000_J.Biosci.Bioeng_90_684 Cloning and sequence analysis of the estA gene encoding enzyme for producing (R)-beta-acetylmercaptoisobutyric acid from Pseudomonas aeruginosa 1001
Hoffmann_2000_FEMS.Microbiol.Lett_184_253 The Pseudomonas aeruginosa phaG gene product is involved in the synthesis of polyhydroxyalkanoic acid consisting of medium-chain-length constituents from non-related carbon sources
Jaspers_2000_J.Bacteriol_182_405 HbpR, a new member of the XylR\/DmpR subclass within the NtrC family of bacterial transcriptional activators, regulates expression of 2-hydroxybiphenyl metabolism in Pseudomonas azelaica HBP1
Stern_2000_FEMS.Microbiol.Lett_185_163 The polyester polyurethanase gene (pueA) from Pseudomonas chlororaphis encodes a lipase
Schober_2000_Appl.Environ.Microbiol_66_1385 Poly(3-hydroxyvalerate) depolymerase of Pseudomonas lemoignei
Watanabe_2000_J.Biol.Chem_275_31016 Versatile transcription of biphenyl catabolic bph operon in Pseudomonas pseudoalcaligenes KF707
Robinson_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1376 Structure of the C123S mutant of dienelactone hydrolase (DLH) bound with the PMS moiety of the protease inhibitor phenylmethylsulfonyl fluoride (PMSF)
Park_2000_J.Microbiol_38_275 Cloning and Sequence Analysis of the xylL Gene Responsible for 4CBA-Dihydrodiol Dehydrogenase from Pseudomonas sp. S-47.
Fischer_2000_FEMS.Microbiol.Lett_190_21 Site-directed mutagenesis of potential catalytic residues in 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase, and hypothesis on the catalytic mechanism of 2,4-dioxygenolytic ring cleavage
Solaiman_2000_Biotechnol.Lett_22_789 Synthesis of poly(hydroxyalkanoates) by Escherichia coli expressing mutated and chimeric PHA synthase genes
Solaiman_2000_Appl.Microbiol.Biotechnol_53_690 Rapid and specific identification of medium-chain-length polyhydroxyalkanoate synthase gene by polymerase chain reaction
Tanaka_2000_J.Biochem_127_597 Glutathione as an essential factor for chaperon-mediated activation of lactonizing lipase (LipL) from Pseudomonas sp. 109
Shimao_2000_Microbiology_146 ( Pt 3)_649 The gene pvaB encodes oxidized polyvinyl alcohol hydrolase of Pseudomonas sp. strain VM15C and forms an operon with the polyvinyl alcohol dehydrogenase gene pvaA
Amada_2000_Biochim.Biophys.Acta_1478_201 Overproduction in Escherichia coli, purification and characterization of a family I.3 lipase from Pseudomonas sp. MIS38
Bosch_2000_Gene_245_65 Complete nucleotide sequence and evolutionary significance of a chromosomally encoded naphthalene-degradation lower pathway from Pseudomonas stutzeri AN10
Lewis_2000_Environ.Microbiol_2_407 A Pseudomonas stutzeri gene cluster encoding the biosynthesis of the CCl4-dechlorination agent pyridine-2,6-bis(thiocarboxylic acid)
Hosoda_2000_Biochem.Biophys.Res.Commun_279_909 Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue
Kimura_2000_J.Exp.Zool_286_656 cDNA cloning of rat prolyl oligopeptidase and its expression in the ovary during the estrous cycle
Dogru_2000_Eur.J.Biochem_267_1397 The gene encoding polyneuridine aldehyde esterase of monoterpenoid indole alkaloid biosynthesis in plants is an ortholog of the alpha\/betahydrolase super family
Visser_2000_Appl.Microbiol.Biotechnol_53_415 Cloning and characterization of an epoxide hydrolase-encoding gene from Rhodotorula glutinis
Clemente_2000_Appl.Microbiol.Biotechnol_53_420 Sequence of PHA synthase gene from two strains of Rhodospirillum rubrum and in vivo substrate specificity of four PHA synthases across two heterologous expression systems
Bresler_2000_Appl.Environ.Microbiol_66_904 Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1
Poelarends_2000_J.Bacteriol_182_2191 Roles of horizontal gene transfer and gene integration in evolution of 1,3-dichloropropene- and 1,2-dibromoethane-degradative pathways
Machida_2000_Yeast_16_71 A 38 kb segment containing the cdc2 gene from the left arm of fission yeast chromosome II: sequence analysis and characterization of the genomic DNA and cDNAs encoded on the segment
Ding_2000_Genes.Cells_5_169 Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.
Ito_2000_J.Biochem_128_673 Substrate recognition mechanism of prolyl aminopeptidase from Serratia marcescens
Li_2000_Proc.Natl.Acad.Sci.U.S.A_97_6902 An acyltransferase catalyzing the formation of diacylglucose is a serine carboxypeptidase-like protein
Molnar_2000_Chem.Biol_7_97 The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90
Julien_2000_Gene_249_153 Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum
Tang_2000_Science_287_640 Cloning and heterologous expression of the epothilone gene cluster
Hernaez_2000_J.Bacteriol_182_5448 Identification of a serine hydrolase which cleaves the alicyclic ring of tetralin
Marek_2000_Biochemistry_39_14082 Crystal structure of the haloalkane dehalogenase from Sphingomonas paucimobilis UT26
Rosenstein_2000_Biochimie_82_1005 Staphylococcal lipases: biochemical and molecular characterization
Longshaw_2000_Microbiology_146 ( Pt 6)_1419 Identification of a second lipase gene, gehD, in Staphylococcus epidermidis: comparison of sequence with those of other staphylococcal lipases
Drouault_2000_Appl.Environ.Microbiol_66_588 Expression of the Staphylococcus hyicus lipase in Lactococcus lactis
Lauer_2000_Eur.J.Biochem_267_1698 Molecular characterization of two genes from Streptomyces tendae Tu901 required for the formation of the 4-formyl-4-imidazolin-2-one-containing nucleoside moiety of the peptidyl nucleoside antibiotic nikkomycin
Schauwecker_2000_Chem.Biol_7_287 Construction and in vitro analysis of a new bi-modular polypeptide synthetase for synthesis of N-methylated acyl peptides
Walczak_2000_FEMS.Microbiol.Lett_183_171 Nonactin biosynthesis: the potential nonactin biosynthesis gene cluster contains type II polyketide synthase-like genes.
Wu_2000_Gene_251_81 The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units
Cote_2000_Microbiology_146 ( Pt 7)_1555 A novel beta-glucoside-specific PTS locus from Streptococcus mutans that is not inhibited by glucose
Aparicio_2000_Chem.Biol_7_895 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis
Brautaset_2000_Chem.Biol_7_395 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway
Wang_2000_Antimicrob.Agents.Chemother_44_3040 Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489
Hiratsu_2000_Mol.Gen.Genet_263_1015 Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei
Suwa_2000_Gene_246_123 Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei
Iwagami_2000_Appl.Environ.Microbiol_66_1499 Characterization of the protocatechuic acid catabolic gene cluster from Streptomyces sp. strain 2065
Xue_2000_Gene_245_203 Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides
Du_2000_FEMS.Microbiol.Lett_189_171 An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003
Du_2000_Chem.Biol_7_623 The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase
Omi_2000_Anim.Genet_31_413 Molecular basis of esterase D polymorphism in the pig
McNeel_2000_J.Nutr.Biochem_11_139 Nutritional deprivation reduces the transcripts for transcription factors and adipocyte-characteristic proteins in porcine adipocytes(1)
McNeel_2000_J.Anim.Sci_78_934 Effect of feed restriction on adipose tissue transcript concentrations in genetically lean and obese pigs
Fulop_2000_EMBO.Rep_1_277 Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
Ruepp_2000_Nature_407_508 The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum
Kawashima_2000_Proc.Natl.Acad.Sci.U.S.A_97_14257 Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium
Weik_2000_Proc.Natl.Acad.Sci.U.S.A_97_623 Specific chemical and structural damage to proteins produced by synchrotron radiation
Claudianos_2000_in.PESTICIDE.RESISTANCE A genomics perspective on mutant aliesterases and metabolic resistance to organophosphates
Kadono-Okuda_2000_Biochem.Biophys.Res.Commun_272_12 Distinctive structural and kinetic properties of an unusual juvenile hormone-hydrolyzing esterase
Hakulinen_2000_J.Struct.Biol_132_180 Three-dimensional structure of the catalytic core of acetylxylan esterase from Trichoderma reesei: insights into the deacetylation mechanism
Glass_2000_Nature_407_757 The complete sequence of the mucosal pathogen Ureaplasma urealyticum
Vedler_2000_Gene_245_161 TfdR, the LysR-type transcriptional activator, is responsible for the activation of the tfdCB operon of Pseudomonas putida 2, 4-dichlorophenoxyacetic acid degradative plasmid pEST4011
Vedler_2000_Gene_255_281 Analysis of the 2,4-dichlorophenoxyacetic acid-degradative plasmid pEST4011 of Achromobacter xylosoxidans subsp. denitrificans strain EST4002
Simpson_2000_Nature_406_151 The genome sequence of the plant pathogen Xylella fastidiosa. The Xylella fastidiosa Consortium of the Organization for Nucleotide Sequencing and Analysis
Miura_2000_Appl.Environ.Microbiol_66_4883 Screening of genes involved in isooctane tolerance in Saccharomyces cerevisiae by using mRNA differential display
Dahlqvist_2000_Proc.Natl.Acad.Sci.U.S.A_97_6487 Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants
Oelkers_2000_J.Biol.Chem_275_15609 A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast
Wu_2000_EMBO.J_19_5672 Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo
Budiman_2000_Genome.Res_10_129 A deep-coverage tomato BAC library and prospects toward development of an STC framework for genome sequencing
Mediavilla_2000_Mol.Microbiol_38_955 Genome organization and characterization of mycobacteriophage Bxb1
Takai_2000_Infect.Immun_68_6840 DNA sequence and comparison of virulence plasmids from Rhodococcus equi ATCC 33701 and 103
Verripsab_2000_Enzyme.Microb.Technol_26_812 From gene to product in yeast: production of fungal cutinase
Fujie_2000_J.Antibiot.(Tokyo)_53_912 FR901469, a novel antifungal antibiotic from an unidentified fungus No.11243. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological properties
Fujie_2000_J.Antibiot.(Tokyo)_53_920 FR901469, a novel antifungal antibiotic from an unidentified fungus No.11243. II. In vitro and in vivo activities
Masunaka_2000_Phytopathology_90_762 Distribution and Characterization of AKT Homologs in the Tangerine Pathotype of Alternaria alternata
Johnson_2000_Mol.Plant.Microbe.Interact_13_742 Cloning and characterization of a cyclic peptide synthetase gene from Alternaria alternata apple pathotype whose product is involved in AM-toxin synthesis and pathogenicity
Kim_2000_Mol.Endocrinol_14_1944 A missense mutation G2320R in the thyroglobulin gene causes non-goitrous congenital primary hypothyroidism in the WIC-rdw rat
Hishinuma_2000_Endocrinology_141_4050 A novel missense mutation (G2320R) in thyroglobulin causes hypothyroidism in rdw rats
Marcel_2000_J.Biol.Chem_275_11603 Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes
Mallender_2000_Biochemistry_39_7753 Acetylthiocholine binds to asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway
Boyd_2000_J.Biol.Chem_275_22401 Probing the active center Gorge of acetylcholinesterase by fluorophores Linked to substituted cysteines
Kraut_2000_Mol.Pharmacol_57_1243 Inactivation studies of acetylcholinesterase with phenylmethylsulfonyl fluoride
Altamirano_2000_J.Neurochem_74_869 The butyrylcholinesterase K-variant shows similar cellular protein turnover and quaternary interaction to the wild-type enzyme
McIlroy_2000_J.Med.Genet_37_182 Butyrylcholinesterase K variant is genetically associated with late onset Alzheimer's disease in Northern Ireland
Lehmann_2000_Hum.Genet_106_447 Association of butyrylcholinesterase K variant with cholinesterase-positive neuritic plaques in the temporal cortex in late-onset Alzheimer's disease
Bachmann_2000_Biosens.Bioelectron_15_193 Improved multianalyte detection of organophosphates and carbamates with disposable multielectrode biosensors using recombinant mutants of Drosophila acetylcholinesterase and artificial neural networks
Shah_2000_J.Cardiovasc.Pharmacol_36_169 Oculohypotensive effect of angiotensin-converting enzyme inhibitors in acute and chronic models of glaucoma
Stander_2000_J.Agric.Food.Chem_48_5736 Screening of commercial hydrolases for the degradation of ochratoxin A
Donaghy_2000_J.Appl.Microbiol_88_458 Purification and characterization of an extracellular feruloyl esterase from the thermophilic anaerobe Clostridium stercorarium
McGehee_2000_Anesthesiology_93_510 Cholinesterase inhibition by potato glycoalkaloids slows mivacurium metabolism
Devlin_2000_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_125_53 Pharmacological identification of acetylcholine receptor subtypes in echinoderm smooth muscle (Sclerodactyla briareus)
Houlihan_2000_Neuropharmacol_39_2533 Effects of diltiazem on human nicotinic acetylcholine and GABA(A) receptors
Andreani_2000_Eur.J.Med.Chem_35_77 4-Aminopyridine derivatives with antiamnesic activity
Villalobos_2000_Aquat.Toxicol_48_309 Thiobencarb-induced embryotoxicity in medaka (Oryzias latipes): stage-specific toxicity and the protective role of chorion
Boyd_2000_Bioorg.Med.Chem.Lett_10_395 2-(Alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2
Biely_2000_Anal.Biochem_286_289 A chromogenic substrate for a beta-xylosidase-coupled assay of alpha-glucuronidase
Jia_2000_Biochemistry_39_3927 Lipases provide a new mechanistic model for polyhydroxybutyrate (PHB) synthases: characterization of the functional residues in chromatium vinosum PHB synthase
Bentley_2000_Chem.Rev_100_3801 Mycophenolic Acid: a one hundred year odyssey from antibiotic to immunosuppressant
Ikemoto_2000_Nihon.Hinyokika.Gakkai.Zasshi_91_556 [Changes in liver function induced by flutamide in patients with prostate cancer (studies in patients treated with total androgen blockage)]
Rotticci_2000_Biochim.Biophys.Acta_1483_132 An active-site titration method for lipases
Moretto_2000_Arch.Toxicol_73_655 The relevance of inhibitor-substrate interactions when measuring neuropathy target esterase inhibition
Shiotsuki_2000_Biosci.Biotechnol.Biochem_64_1681 Characterization and affinity purification of juvenile hormone esterase from Bombyx mori
Yu_2000_Circ.Res_87_992 Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids
Ohtsubo_2000_Gene_256_223 Expression of the bph genes involved in biphenyl\/PCB degradation in Pseudomonas sp. KKS102 induced by the biphenyl degradation intermediate, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
Koellner_2000_J.Mol.Biol_296_713 Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica
Kudo_2000_J.Pharmacol.Exp.Ther_294_80 Phenacetin deacetylase activity in human liver microsomes: distribution, kinetics, and chemical inhibition and stimulation
Bretaud_2000_Ecotoxicol.Environ.Saf_47_117 Effects of carbofuran, diuron, and nicosulfuron on acetylcholinesterase activity in goldfish (Carassius auratus)
Sancho_2000_Ecotoxicol.Environ.Saf_46_81 Cholinesterase activity and hematological parameters as biomarkers of sublethal molinate exposure in Anguilla anguilla
Spiegelstein_2000_Pharm.Res_17_216 Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid
Martin_2000_J.Pharmacol.Exp.Ther_294_1209 Cannabinoid properties of methylfluorophosphonate analogs
Wilson_2000_J.Androl_21_220 Dipeptidylpeptidase IV activities are elevated in prostate cancers and adjacent benign hyperplastic glands
Morain_2000_Br.J.Clin.Pharmacol_50_350 Pharmacodynamic and pharmacokinetic profile of S 17092, a new orally active prolyl endopeptidase inhibitor, in elderly healthy volunteers. A phase I study
Petit_2000_Br.J.Pharmacol_130_1613 Novel proline endopeptidase inhibitors do not modify Abeta40\/42 formation and degradation by human cells expressing wild-type and swedish mutated beta-amyloid precursor protein
Wang_2000_Biochim.Biophys.Acta_1480_191 Modifications of aclacinomycin T by aclacinomycin methyl esterase (RdmC) and aclacinomycin-10-hydroxylase (RdmB) from Streptomyces purpurascens
Jensen_2000_J.Econ.Entomol_93_464 Mechanisms associated with methiocarb resistance in Frankliniella occidentalis (Thysanoptera: Thripidae)
Weinstock_2000_J.Neural.Transm.Suppl__157 TV3326, a novel neuroprotective drug with cholinesterase and monoamine oxidase inhibitory activities for the treatment of Alzheimer's disease
Ros_2000_Eur.J.Pharmacol_390_7 Effects of CI-1002 and CI-1017 on spontaneous synaptic activity and on the nicotinic acetylcholine receptor of Torpedo electric organ
Lahiri_2000_Acta.Neurol.Scand.Suppl_176_60 Cholinesterase inhibitors, beta-amyloid precursor protein and amyloid beta-peptides in Alzheimer's disease
ElAzab_2000_Org.Lett_2_2757 An expedient route to the Calabar bean alkaloids (-)-physovenine and (-)-physostigmine
Trabace_2000_J.Pharmacol.Exp.Ther_294_187 Biochemical and neurobehavioral profile of CHF2819, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease
Harris_2000_Food.Addit.Contam_17_491 How the variability issue was uncovered: the history of the UK residue variability findings
Kolesnikov_2000_Proc.Natl.Acad.Sci.U.S.A_97_13526 Enzyme mimicry by the antiidiotypic antibody approach
Tramontano_2000_Appl.Biochem.Biotechnol_83_233 Inhibition and labeling of enzymes and abzymes by phosphonate diesters
Alagiakrishnan_2000_Hawaii.Med.J_59_57 Use of donepezil in elderly patients with Alzheimer's disease--a Hawaii based study
Camps_2000_Mol.Pharmacol_57_409 Huprine X is a Novel High-Affinity Inhibitor of Acetylcholinesterase That Is of Interest for Treatment of Alzheimer's Disease
Ogura_2000_Nihon.Yakurigaku.Zasshi_115_45 [Pharmacological properties of donepezil hydrochloride (Aricept), a drug for Alzheimer's disease]
Kosasa_2000_Eur.J.Pharmacol_389_173 Inhibitory effect of orally administered donepezil hydrochloride (E2020), a novel treatment for Alzheimer's disease, on cholinesterase activity in rats
Weiner_2000_J.Clin.Psychiatry_61_487 Effects of donepezil on emotional\/behavioral symptoms in Alzheimer's disease patients
Sugimoto_2000_Curr.Med.Chem_7_303 Donepezil Hydrochloride (E2020) and Other Acetylcholinesterase Inhibitors
Ogura_2000_Methods.Find.Exp.Clin.Pharmacol_22_89 Donepezil, a centrally acting acetylcholinesterase inhibitor, alleviates learning deficits in hypocholinergic models in rats
Ogura_2000_Methods.Find.Exp.Clin.Pharmacol_22_609 Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro
Cummings_2000_Am.J.Geriatr.Psychiatry_8_134 The relationship between donepezil and behavioral disturbances in patients with Alzheimer's disease
Jann_2000_Pharmacotherapy_20_1 Rivastigmine, a new-generation cholinesterase inhibitor for the treatment of Alzheimer's disease
Kaur_2000_Curr.Med.Chem_7_273 Molecular modelling and QSAR of reversible acetylcholines-terase inhibitors
Kristensen_2000_J.Econ.Entomol_93_1788 Selection and reversion of azamethipos-resistance in a field population of the housefly Musca domestica (Diptera: Muscidae), and the underlying biochemical mechanisms
Ostergaard_2000_Anesthesiology_92_1581 The influence of drug-induced low plasma cholinesterase activity on the pharmacokinetics and pharmacodynamics of mivacurium
Liu_2000_Neurosci.Lett_282_165 Bis(7)-tacrine, a novel acetylcholinesterase inhibitor, reverses AF64A-induced deficits in navigational memory in rats
Wu_2000_Neurosci.Lett_288_95 Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor [corrected]
Wu_2000_Neurosci.Lett_290_84 Corrigendum to 'Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor'
Xiao_2000_Neurosci.Lett_290_197 Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine
Gopal_2000_Biochem.Biophys.Res.Commun_279_516 Mutagenesis of organophosphorus hydrolase to enhance hydrolysis of the nerve agent VX
Nomura_2000_Pestic.Biochem.Physiol_66_73 The Genotype and Heredity of Modified Acetylcholinesterase of the Green Rice Leafhopper (Nephotettix cincticeps Uhler)
Hamers_2000_Toxicol.Sci_58_60 A small-volume bioassay for quantification of the esterase inhibiting potency of mixtures of organophosphate and carbamate insecticides in rainwater: development and optimization
Matsuda_2000_Leg.Med.(Tokyo)_2_55 Changes in mRNA expression levels of synaptic- and target tissue-specific proteins after organophosphate exposure
Zhu_2000_Pestic.Biochem.Physiol_68_138 Organophosphate Resistance Mediated by Alterations of Acetylcholinesterase in a Resistant Clone of the Greenbug, Schizaphis graminum (Homoptera: Aphididae)
Wong_2000_Biochemistry_39_5750 Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagenesis
Sheets_2000_Neurotoxicol_21_57 A consideration of age-dependent differences in susceptibility to organophosphorus and pyrethroid insecticides
Waldstein_2000_J.Econ.Entomol_93_1768 Synergism of tebufenozide in resistant and susceptible strains of obliquebanded leafroller (Lepidoptera: Tortricidae) and resistance to new insecticides
Kitamura_2000_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_126_259 Whole-body metabolism of the organophosphorus pesticide, fenthion, in goldfish, Carassius auratus
Guillou_2000_Bioorg.Med.Chem.Lett_10_637 Potent acetylcholinesterase inhibitors: design, synthesis and structure-activity relationships of alkylene linked bis-galanthamine and galanthamine-galanthaminium salts
Jones_2000_J.Toxicol.Environ.Health.A_61_695 Subchronic effects following a single sarin exposure on blood-brain and blood-testes barrier permeability, acetylcholinesterase, and acetylcholine receptors in the central nervous system of rat: a dose-response study
Santos_2000_Clin.Cancer.Res_6_2012 Metabolism of irinotecan (CPT-11) by CYP3A4 and CYP3A5 in humans
Groenewold_2000_J.Am.Soc.Mass.Spectrom_11_69 Characterization of VX on concrete using ion trap secondary ionization mass spectrometry
Kardos_2000_Toxicol.Sci_58_118 Interactions of the organophosphates paraoxon and methyl paraoxon with mouse brain acetylcholinesterase
Karpouzas_2000_J.Appl.Microbiol_89_40 Factors influencing the ability of Pseudomonas putida strains epI and II to degrade the organophosphate ethoprophos
Cavalier_2000_Acc.Chem.Res_33_579 Covalent inhibition of digestive lipases by chiral phosphonates
Greig_2000_Acta.Neurol.Scand.Suppl_176_74 The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics
Das_2000_J.Assoc.Physicians.India_48_540 Encephalopathy, intermediate syndrome and delayed polyneuropathy in acute black Danadar (Phorate 10 CG) poisoning
Cape_2000_Eur.J.Neurosci_12_2166 Effects of glutamate agonist versus procaine microinjections into the basal forebrain cholinergic cell area upon gamma and theta EEG activity and sleep-wake state
Sweet_2000_J.Clin.Psychopharmacol_20_181 Pharmacologic profile of perphenazine's metabolites
Chaney_2000_Toxicol.Appl.Pharmacol_165_107 Acute effects of an insect repellent, N,N-diethyl-m-toluamide, on cholinesterase inhibition induced by pyridostigmine bromide in rats
Grauer_2000_Toxicol.Appl.Pharmacol_164_301 Stress does not enable pyridostigmine to inhibit brain cholinesterase after parenteral administration
Li_2000_Neurotoxicol_21_541 Muscarinic receptor-mediated pyridostigmine-induced neuronal apoptosis
Niesen_2000_Neurology_54_1873 Pyridostigmine-induced microcephaly
Prasad_2000_Neurochem.Res_25_19 Interactions of bovine brain tubulin with pyridostigmine bromide and N,N'-diethyl-m-toluamide
Somani_2000_J.Appl.Toxicol_20_327 Interactive and delayed effects of pyridostigmine and physical stress on biochemical and histological changes in peripheral tissues of mice
Sinton_2000_Toxicol.Appl.Pharmacol_165_99 Stressful manipulations that elevate corticosterone reduce blood-brain barrier permeability to pyridostigmine in the Rat
Servatius_2000_Physiol.Behav_69_239 Effects of inescapable stress and treatment with pyridostigmine bromide on plasma butyrylcholinesterase and the acoustic startle response in rats
Verma-Ahuja_2000_Arch.Toxicol_74_539 Delayed effects of pyridostigmine and exercise training on acetylcholinesterase and muscle tension in mouse lower extremity
Alhomida_2000_Toxicology_147_33 Kinetic analysis of the toxicological effect of tacrine (Cognex) on human retinal acetylcholinesterase activity
Heuser_2000_N.Engl.J.Med_342_1674\; author reply 1675 Mass psychogenic illness attributed to toxic exposure at a high school
Wright_2000_J.Econ.Entomol_93_7 Larval susceptibility of an insecticide-resistant western corn rootworm (Coleoptera: Chrysomelidae) population to soil insecticides: laboratory bioassays, assays of detoxification enzymes, and field performance
Johnson_2000_Mol.Immunol_37_707 Cholinesterase-like catalytic antibodies: reaction with substrates and inhibitors
Van Belle_2000_J.Mol.Biol_298_705 Pathways of ligand clearance in acetylcholinesterase by multiple copy sampling
Kamal_2000_Biochem.Pharmacol_60_561 Kinetics of human acetylcholinesterase inhibition by the novel experimental Alzheimer therapeutic agent, tolserine
Fort_2000_Teratog.Carcinog.Mutagen_20_35 Evaluation of the developmental toxicity of thalidomide using frog embryo teratogenesis assay-xenopus (FETAX): biotransformation and detoxification
Quistad_2000_J.Biochem.Mol.Toxicol_14_51 Sensitivity of blood-clotting factors and digestive enzymes to inhibition by organophosphorus pesticides
Vayron_2000_Proc.Natl.Acad.Sci.U.S.A_97_7058 Toward antibody-catalyzed hydrolysis of organophosphorus poisons
Herholz_2000_J.Neural.Transm.(Vienna)_107_1457 In-vivo measurements of regional acetylcholine esterase activity in degenerative dementia: comparison with blood flow and glucose metabolism
Crapo_2000_Am.J.Respir.Crit.Care.Med_161_309 Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999
Ogino_2000_J.Biosci.Bioeng_89_451 Purification and characterization of organic solvent-stable lipase from organic solvent-tolerant Pseudomonas aeruginosa LST-03
Jaganathan_2000_BMC.Biochem_1_3 A direct method to visualise the aryl acylamidase activity on cholinesterases in polyacrylamide gels
Liebeton_2000_Chem.Biol_7_709 Directed evolution of an enantioselective lipase
Arsan_2000_Biotechnol.Bioeng_69_222 Selectivity of Rhizomucor miehei lipase as affected by choice of cosubstrate system in ester modification reactions in organic media
Boger_2000_Proc.Natl.Acad.Sci.U.S.A_97_5044 Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide
Kato_2000_J.Anesth_14_30 Inhibition of human plasma cholinesterase and erythrocyte acetylcholinesterase by nondepolarizing neuromuscular blocking agents
van Pee_2000_Biol.Chem_381_1 Enzymatic halogenation catalyzed via a catalytic triad and by oxidoreductases
Myers_2000_Science_287_2196 A whole-genome assembly of Drosophila
Cavallotti_2000_Neurochem.Int_36_75 Quantification of acetylcholinesterase-positive structures in human thymus during development and aging
Leitinger_2000_J.Comp.Neurol_416_345 Cytochemical evidence that acetylcholine is a neurotransmitter of neurons that make excitatory and inhibitory outputs in the locust ocellar visual system
Cummings_2000_Am.J.Psychiatry_157_4 Cholinesterase inhibitors: A new class of psychotropic compounds
Li_2000_J.Neurosci_20_149 Neuronal-glial interactions mediated by interleukin-1 enhance neuronal acetylcholinesterase activity and mRNA expression
Rieu_2000_Eur.J.Biochem_267_583 Exosomes released during reticulocyte maturation bind to fibronectin via integrin alpha4beta1
Proctor_2000_Curr.Med.Chem_7_295 Synthesis of tacrine analogues and their structure-activity relationships
Ishihara_2000_Curr.Med.Chem_7_341 Central Selective Acetylcholinesterase Inhibitor with Neurotrophic Activity: Structure-Activity Relationships of TAK-147 and Related Compounds
Adhami_2000_Neurotoxicol.Teratol_22_41 Intrahippocampal cholinergic-rich transplants restore lead-induced deficits: a preliminary study in rats
Milatovic_2000_Neurosci.Lett_278_25 Spin trapping agent phenyl-N-tert-butylnitrone prevents diisopropylphosphorofluoridate-induced excitotoxicity in skeletal muscle of the rat
Pavia_2000_Neurosci.Lett_278_69 Repeated intracerebroventricular administration of beta-amyloid(25-35) to rats decreases muscarinic receptors in cerebral cortex
Kasa_2000_Neurosci.Lett_278_117 Human amyloid-beta1-42 applied in vivo inhibits the fast axonal transport of proteins in the sciatic nerve of rat
Mills_2000_J.Urol_163_646 Studies of the pathophysiology of idiopathic detrusor instability: the physiological properties of the detrusor smooth muscle and its pattern of innervation
Rossi_2000_J.Neurosci_20_919 Local Control of Acetylcholinesterase Gene Expression in Multinucleated Skeletal Muscle Fibers: Individual Nuclei Respond to Signals from the Overlying Plasma Membrane
Fetzner_2000_Naturwiss_87_59 Enzymes Involved in the Aerobic Bacterial Degradation of N-Heteroaromatic Compounds: Molybdenum Hydroxylases and Ring-Opening 2,4-Dioxygenases
Bompard-Gilles_2000_Structure.Fold.Des_8_153 A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-Ala-esterase\/amidase from Ochrobactrum anthropi
Barak_2000_Biochemistry_39_1156 Evidence for P-N bond scission in phosphoroamidate nerve agent adducts of human acetylcholinesterase
van Dyck_2000_Arch.Gen.Psychiatry_57_157 Extended-release physostigmine in Alzheimer disease: a multicenter, double-blind, 12-week study with dose enrichment. Physostigmine Study Group
Ricordel_2000_Ann.Pharm.Fr_58_5 [Chemical weapons: antidotes view about the real means, perspectives]
Goldblum_2000_J.Ocul.Pharmacol.Ther_16_29 Topical rivastigmine, a selective acetylcholinesterase inhibitor, lowers intraocular pressure in rabbits
Wlodek_2000_Biopolymers_53_265 Electrostatic steering of substrate to acetylcholinesterase: analysis of field fluctuations
Lesser_2000_J.Toxicol.Environ.Health_59_57 Comparison of oxime-initiated reactivation of organophosphorous-inhibited acetylcholinesterase in brains of avian embryos
Du_2000_J.Mol.Biol_296_1017 Stability of a structural scaffold upon activity transfer: X-ray structure of a three fingers chimeric protein
Ben_2000_Photochem.Photobiol_71_124 Porphyrins and related compounds as photoactivatable insecticides. 3. Laboratory and field studies
Prall_2000_Life.Sci_66_835 Acetylcholinesterase activity in chronic renal failure
Wajima_2000_Anaesth.Intensive.Care_28_46 The effect of previous administration of nizatidine on the neuromuscular effects of vecuronium and the effect of nizatidine on gastric secretion
Imbimbo_2000_Dement.Geriatr.Cogn.Disord_11_17 A 6-month, double-blind, placebo-controlled trial of eptastigmine in Alzheimer's disease
Abe_2000_J.Gastroenterol_35_28 Focal therapeutic efficacy of transcatheter arterial infusion of styrene maleic acid neocarzinostatin for hepatocellular carcinoma
Fernandez_2000_Mov.Disord_15_173 Donepezil for Huntington's disease
Bai_2000_Curr.Med.Chem_7_355 Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease
Evans_2000_Int.J.Geriatr.Psychiatry_15_50 Sustained cognitive improvement following treatment of Alzheimer's disease with donepezil
Philippens_2000_Pharmacol.Biochem.Behav_65_175 Scopolamine augments the efficacy of physostigmine against soman poisoning in guinea pigs
Martyn_2000_Anesthesiology_92_31 Neuromuscular effects of mivacurium in 2- to 12-yr-old children with burn injury
Nagy_2000_Proc.Natl.Acad.Sci.U.S.A_97_829 Stability of cytotoxic luteinizing hormone-releasing hormone conjugate (AN-152) containing doxorubicin 14-O-hemiglutarate in mouse and human serum in vitro: implications for the design of preclinical studies
Kawasaki_2000_J.Hand.Surg.[Am]_25_104 Identification of myelinated motor and sensory axons in a regenerating mixed nerve
Boudreau-Lariviere_2000_Am.J.Physiol.Regul.Integr.Comp.Physiol_278_R140 Myotubes originating from single fast and slow satellite cells display similar patterns of AChE expression
Hellstrom-Lindahl_2000_J.Neurochem_74_777 Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists
Jensen_2000_Ugeskr.Laeger_162_161 [Mutation of the plasma cholinesterase gene and anesthesia. Information from the Danish Cholinesterase Registry]
Chassany_2000_Drug.Saf_22_53 Drug-induced diarrhoea
Hwang_2000_Anesth.Analg_90_421 An analysis of drug interaction between morphine and neostigmine in rats with nerve-ligation injury
Hasler_2000_Gastroenterology_118_443 Neostigmine for acute colonic pseudo-obstruction: new use for an old drug?
Broberger_2000_Brain.Res.Mol.Brain.Res_75_25 Differential effects of intrastriatally infused fully and endcap phosphorothioate antisense oligonucleotides on morphology, histochemistry and prodynorphin expression in rat brain
Bassant_2000_Eur.J.Pharmacol_387_151 Sustained effect of metrifonate on cerebral glucose metabolism after immunolesion of basal forebrain cholinergic neurons in rats
Zajc_2000_Pflugers.Arch_439_R66 Nonradioactive northern blotting for the determination of acetylcholinesterase mRNA. Comparison to the radioactive technique
Ribaric_2000_Pflugers.Arch_439_R217 Modification of skeletal muscle AChE expression by a novel method of stimulus application to the peripheral nerve
Philippens_2000_Toxicol.Sci_53_84 Subchronic physostigmine pretreatment in marmosets: absence of side effects and effectiveness against soman poisoning with negligible postintoxication incapacitation
Yano_2000_Toxicol.Sci_53_135 Lack of carcinogenicity of chlorpyrifos insecticide in a high-dose, 2-year dietary toxicity study in Fischer 344 rats
Zapata_2000_Synapse_35_272 Role of high-affinity choline uptake on extracellular choline and acetylcholine evoked by NMDA
Cassell_2000_Neurosci_95_489 Glycine receptor (gephyrin) immunoreactivity is present on cholinergic neurons in the dorsal vagal complex
Sakai_2000_J.Comp.Neurol_417_164 Pallidal and cerebellar afferents to pre-supplementary motor area thalamocortical neurons in the owl monkey: a multiple labeling study
Buccafusco_2000_Brain.Res_852_76 Prevention of precipitated withdrawal symptoms by activating central cholinergic systems during a dependence-producing schedule of morphine in rats
Meier-Ruge_2000_Pediatr.Surg.Int_16_2 Histopathologic observations of anorectal abnormalities in anal atresia
Galindo-Reyes_2000_Chemosphere_40_233 Enzymatic and osmoregulative alterations in white shrimp Litopenaeus vannamei exposed to pesticides
Ohno_2000_Ann.Neurol_47_162 The spectrum of mutations causing end-plate acetylcholinesterase deficiency
Machado_2000_Hum.Pathol_31_3 Cardiac autonomic denervation in congestive heart failure: comparison of Chagas' heart disease with other dilated cardiomyopathy
Wrobel_2000_Ann.Anat_182_13 On the innervation of the donkey testis
Lallement_2000_Ann.Pharm.Fr_58_13 [Pretreatment of organophosphate poisoning: potential interests of huperzine A]
Lallement_2000_Ann.Pharm.Fr_58_18 [Interest in an glutamate antagonistic compound for the treatment of organophosphate poisoning]
Adel-Patient_2000_J.Immunol.Methods_235_21 Evaluation of a high IgE-responder mouse model of allergy to bovine beta-lactoglobulin (BLG): development of sandwich immunoassays for total and allergen-specific IgE, IgG1 and IgG2a in BLG-sensitized mice
Huckstorf_2000_Brain.Res.Dev.Brain.Res_119_169 Effects of hindlimb unloading on neuromuscular development of neonatal rats
Dembele_2000_Ecotoxicol.Environ.Saf_45_49 Concentration effects of selected insecticides on brain acetylcholinesterase in the common carp (Cyprinus carpio L.)
Kojic_2000_Proc.Natl.Acad.Sci.U.S.A_97_1841 Columnar distribution of serotonin-dependent plasticity within kitten striate cortex
Izurieta-Sanchez_2000_Brain.Res_856_250 Neostigmine influences the L-dopa-induced extracellular dopamine levels in the striatum
Deprez_2000_Protein.Eng_13_27 Molecular modeling of the collagen-like tail of asymmetric acetylcholinesterase
Danet_2000_Biopolymers_57_37 Flow analysis for determination of paraoxon with use of immobilized acetylcholinesterase reactor and new type of chemiluminescent reaction
Rosser_2000_Dev.Dyn_217_50 Repression of myosin isoforms in developing and denervated skeletal muscle fibers originates near motor endplates
Gupta_2000_Alcohol_20_9 Influence of ethanol on lead distribution and biochemical changes in rats exposed to lead
Machard_2000_Antimicrob.Agents.Chemother_44_546 A sensitive amphotericin B immunoassay for pharmacokinetic and distribution studies
Carmona_2000_Drug.Metab.Dispos_28_367 Butyrylcholinesterase accelerates cocaine metabolism: in vitro and in vivo effects in nonhuman primates and humans
Rey_2000_Int.J.Vitam.Nutr.Res_70_24 Dietary polyunsaturated fatty acids and plasma butyrylcholinesterase activity in piglets
Srivastava_2000_Food.Chem.Toxicol_38_65 Clinical, biochemical and neurobehavioural studies of workers engaged in the manufacture of quinalphos
Harris_2000_Exp.Neurol_161_517 The neurotoxicity of the venom phospholipases A(2), notexin and taipoxin
Leposavic_2000_Neuroimmunomodulation_7_59 Castration of sexually immature rats affects sympathetic innervation of the adult thymus
Braselton_2000_J.Vet.Diagn.Invest_12_15 Gas chromatography\/mass spectrometry identification and quantification of isazophos in a famphur pour-on and in bovine tissues after a toxic exposure
Owen_2000_Anesthesiology_92_361 Low-dose clonidine and neostigmine prolong the duration of intrathecal bupivacaine-fentanyl for labor analgesia
O'Hara_2000_West.J.Med_172_115 Update on Alzheimer's disease: recent findings and treatments
Perkins_2000_Toxicol.Sci_53_308 In vivo acetylcholinesterase inhibition, metabolism, and toxicokinetics of aldicarb in channel catfish: role of biotransformation in acute toxicity
Mattsson_2000_Toxicol.Sci_53_438 Lack of differential sensitivity to cholinesterase inhibition in fetuses and neonates compared to dams treated perinatally with chlorpyrifos
Yang_2000_J.Toxicol.Clin.Toxicol_38_43 Carbofuran-induced delayed neuropathy
Sudakin_2000_J.Toxicol.Clin.Toxicol_38_47 Intermediate syndrome after malathion ingestion despite continuous infusion of pralidoxime
Wang_2000_Neuropharmacol_39_497 Gender differences in the effect of rivastigmine on brain cholinesterase activity and cognitive function in rats
Sarangi_2000_Clin.Nucl.Med_25_187 Anterior choroidal artery infarction presenting as a progressive cognitive deficit
Murakami_2000_Behav.Brain.Res_109_83 Ameliorative effect of tacrine on spatial memory deficit in chronic two-vessel occluded rats is reversible and mediated by muscarinic M1 receptor stimulation
Crumpton_2000_Brain.Res_857_87 Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: effects on nuclear transcription factors involved in cell replication and differentiation
Hayashi_2000_Brain.Res_858_167 The development of terminal schwann cells associated with periodontal ruffini endings in the rat incisor ligament
McConkey_2000_Anaesth.Intensive.Care_28_82 Congenital myasthenic syndrome: a rare, potentially treatable cause of respiratory failure in a floppy infant
Fetterer_2000_J.Parasitol_86_1 Characterization of acid phosphatase and phosphorylcholine hydrolase in adult Haemonchus contortus
Lepinard_2000_Prenat.Diagn_20_70 Prenatal diagnosis of pyloric atresia-junctional epidermolysis bullosa syndrome in a fetus not known to be at risk
Morel_2000_J.Biol.Chem_275_7304 Comparative expression of homologous proteins. A novel mode of transcriptional regulation by the coding sequence folding compatibility of chimeras
Diamantino_2000_Ecotoxicol.Environ.Saf_45_253 Toxicity of Sodium Molybdate and Sodium Dichromate to Daphnia magna Straus Evaluated in Acute, Chronic, and Acetylcholinesterase Inhibition Tests
Romero_2000_Respiration_67_18 Light's criteria revisited: consistency and comparison with new proposed alternative criteria for separating pleural transudates from exudates
Park_2000_J.Reconstr.Microsurg_16_135 Direct muscle neurotization in rat soleus muscle
Aura_2000_Eur.J.Pharmacol_390_313 Pre-training blocks the improving effect of tetrahydroaminoacridine and D-cycloserine on spatial navigation performance in aged rats
Biagioni_2000_Int.J.Dev.Neurosci_18_93 Activation of neurospecific gene expression by antennapedia homeobox peptide
Nakajima_2000_J.Chem.Neuroanat_18_31 Immunohistochemical demonstration of choline acetyltransferase of a peripheral type (pChAT) in the enteric nervous system of rats
Mullaney_2000_Ophthalmology_107_504 The natural history and ophthalmic involvement in childhood myasthenia gravis at the hospital for sick children
Das_2000_Toxicol.Lett_114_11 Chronic toxic effects of quinalphos on some biochemical parameters in labeo rohita (Ham.)
Livingston_2000_Int.J.Geriatr.Psychiatry_15_203 How useful are cholinesterase inhibitors in the treatment of Alzheimer's disease? A number needed to treat analysis
Grossberg_2000_Int.J.Geriatr.Psychiatry_15_242 Lack of adverse pharmacodynamic drug interactions with rivastigmine and twenty-two classes of medications
Davitt_2000_J.Pediatr.Ophthalmol.Strabismus_37_5 Childhood myasthenia
Gu_2000_Int.J.Dev.Neurosci_18_177 Repeated immunolesions display diminished stress response signal
Gutierrez_2000_J.Comp.Neurol_419_61 Neurochemical and connectional organization of the dorsal pulvinar complex in monkeys
Milan_2000_J.Comp.Neurol_419_96 Patterns of calretinin, calbindin, and tyrosine-hydroxylase expression are consistent with the prosomeric map of the frog diencephalon
Blass_2000_Alzheimer.Dis.Assoc.Disord_14_39 Randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety and tolerability of metrifonate in patients with probable Alzheimer disease. The Metrifonate Study Group
Furey_2000_Brain.Res.Bull_51_213 Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans
Niranjan_2000_Mol.Cell.Biochem_204_57 Membrane changes in rat erythrocyte ghosts on ghee feeding
Hand_2000_Mol.Cell.Biochem_204_65 Stabilization of collagen-tailed acetylcholinesterase in muscle cells through extracellular anchorage by transglutaminase-catalyzed cross-linking
Milatovic_2000_Free.Radic.Biol.Med_28_597 Atypical effect of some spin trapping agents: reversible inhibition of acetylcholinesterase
Szenohradszky_2000_Anesthesiology_92_708 Effect of edrophonium and neostigmine on the pharmacokinetics and neuromuscular effects of mivacurium
Honda_2000_Brain.Res_859_38 Involvement of M(3) muscarinic receptors of the spinal cord in formalin-induced nociception in mice
Xavier_2000_Biosens.Bioelectron_14_895 Fiber optic monitoring of carbamate pesticides using porous glass with covalently bound chlorophenol red
Mazurek_2000_N.Engl.J.Med_342_821 Treatment of Alzheimer's disease [letter]
Chevalier_2000_J.Comp.Neurol_419_137 Honeycomb-like structure of the intermediate layers of the rat superior colliculus, with additional observations in several other mammals: AChE patterning
Otoguro_2000_J.Antibiot.(Tokyo)_53_50 Arisugacins C and D, novel acetylcholinesterase inhibitors and their related novel metabolites produced by Penicilium sp. FO-4259-11
Kumura_2000_Clin.Chim.Acta_294_27 DX-9065a, a specific factor Xa inhibitor, as a universal anticoagulant for blood collection tubes
Marti_2000_Neurologia_15_15 [Dementia with Lewy bodies]
Hagforsen_2000_Br.J.Dermatol_142_234 The distribution of choline acetyltransferase- and acetylcholinesterase-like immunoreactivity in the palmar skin of patients with palmoplantar pustulosis
Rampa_2000_Bioorg.Med.Chem_8_497 Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1,2-b]-quinolin-10-ylamine derivatives
Hirashima_2000_Bioorg.Med.Chem_8_653 Docking study of enantiomeric fonofos oxon bound to the active site of Torpedo californica acetylcholinesterase
Shikiar_2000_J.Am.Geriatr.Soc_48_268 The impact of metrifonate therapy on caregivers of patients with Alzheimer's disease: results from the MALT clinical trial. Metrifonate in Alzheimer's Disease Trial
Goding_2000_J.Leukoc.Biol_67_285 Ecto-enzymes: physiology meets pathology
Golbraikh_2000_Eur.J.Med.Chem_35_123 Validation of protein-based alignment in 3D quantitative structure-activity relationships with CoMFA models
Yang_2000_Int.J.Biochem.Cell.Biol_32_549 Neurotoxin 6-aminonicotinamide affects levels of soluble proteins and enzyme activities in various tissues of golden hamsters
Coiro_2000_J.Investig.Med_48_133 Dopaminergic and cholinergic involvement in the inhibitory effect of dexamethasone on the TSH response to TRH
Wenk_2000_Life.Sci_66_1079 No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use
Mack_2000_Prog.Neurobiol_60_607 The key role of butyrylcholinesterase during neurogenesis and neural disorders: an antisense-5'butyrylcholinesterase-DNA study
Dave_2000_Z.Naturforsch.C_55_100 Tissue cholinesterases. A comparative study of their kinetic properties
Tsigelny_2000_Protein.Sci_9_180 Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations
Hoyos_2000_J.Pineal.Res_28_150 Serum cholesterol and lipid peroxidation are decreased by melatonin in diet-induced hypercholesterolemic rats
Ward_2000_Exp.Neurol_162_297 BDNF is needed for postnatal maturation of basal forebrain and neostriatum cholinergic neurons in vivo
Hathway_2000_Biol.Rev.Camb.Philos.Soc_75_95 Toxic action\/toxicity
Blasina_2000_Cell.Tissue.Res_299_173 Evidence for a noncholinergic function of acetylcholinesterase during development of chicken retina as shown by fasciculin
Gimenez-Pardo_2000_Parasite_7_47 Presence of cholinesterases in Echinococcus granulosus protoscolices
Foy_2000_Psychother.Psychosom_69_59 Assessment and treatment of dementia in medical patients
Yang_2000_J.Lipid.Res_41_48 The open lid mediates pancreatic lipase function
Jing_2000_Embo.J_19_164 New structural motifs on the chymotrypsin fold and their potential roles in complement factor B
Molgaard_2000_Structure.Fold.Des_8_373 Rhamnogalacturonan acetylesterase elucidates the structure and function of a new family of hydrolases
Pandit_2000_J.Biol.Chem_275_30610 Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis
Caillol_2000_J.Cell.Biochem_79_628 Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cells
Dominguez_2000_FEBS.Lett_482_109 Interactions of bile salt micelles and colipase studied through intermolecular nOes
Cottrell_2000_Biochemistry_39_15129 Identification of critical residues in the active site of porcine membrane-bound aminopeptidase P
Gorokhov_2000_Biophys.J_79_2909 Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase\/N-sulfotransferase
Samochocki_2000_Acta.Neurol.Scand.Suppl_176_68 Galantamine is an allosterically potentiating ligand of the human alpha4\/beta2 nAChR
Bhaskaran_2000_J.Assoc.Physicians.India_48_439 Familial infantile myaesthenia
Avasthi_2000_J.Assoc.Physicians.India_48_794 Serial neuro-electrophysiological studies in acute organophosphate poisoning--correlation with clinical findings, serum cholinesterase levels and atropine dosages
Ray_2000_J.Exp.Clin.Cancer.Res_19_505 Stimulation of megakaryocytopoiesis and platelet production during growth of an experimental lymphoma
Shobha_2000_J.Assoc.Physicians.India_48_1197 Glycosuria in organophosphate and carbamate poisoning
Shapira_2000_J.Med_31_143 Anesthesia for victims of nerve agents undergoing surgery: establishment of a management protocol
Miyazawa_2000_Hematol_5_233 Megakaryocytic Maturation is Regulated by Maintaining a Balance Against Cytokine Induced-cell Proliferation: Steel Factor Retards Thrombopoietin-induced Megakaryocytic Differentiation While Synergistically Stimulating Mitogenesis\; Hematopoiesis
Yli-Mattila_2000_Exp.Appl.Acarol_24_863 Species and strain identification of the predatory mite Euseius finlandicus by RAPD-PCR and ITS sequences
Varnagy_2000_Acta.Vet.Hung_48_113 Interaction of Dithane M-45 (mancozeb) and lead acetate during a teratogenicity test in rats
Turi_2000_Acta.Vet.Hung_48_139 Determination of residues of pyrethroid and organophosphorous ectoparasiticides in foods of animal origin
Dileep_2000_Indian.J.Exp.Biol_38_1245 Influence of metham sodium on suppression of collar rot disease of peanut, in vitro antibiosis, siderophore production and root colonization by a fluorescent pseudomonad strain FPO4
Steevens_2000_Mar.Environ.Res_50_113 Interactions of chlorpyrifos and methyl mercury: a mechanistic approach to assess chemical mixtures
Rodriguez-Fuentes_2000_Mar.Environ.Res_50_357 Environmental monitoring using acetylcholinesterase inhibition in vitro. A case study in two Mexican lagoons
Minier_2000_Mar.Environ.Res_50_373 Flounder health status in the Seine Bay. A multibiomarker study
Knopman_2000_Int.J.Neuropsychopharmacol_3_13 Management of cognition and function: new results from the clinical trials programme of Aricept(R) (donepezil HCl)
Mega_2000_Int.J.Neuropsychopharmacol_3_3 The cholinergic deficit in Alzheimer's disease: impact on cognition, behaviour and function
Nistiar_2000_Folia.Microbiol.(Praha)_45_567 Influence of intoxication with organophosphates on rumen bacteria and rumen protozoa and protective effect of clinoptilolite-rich zeolite on bacterial and protozoan concentration in rumen
Girbal_2000_Biodegradation_11_371 Growth rate influences reductive biodegradation of the organophosphorus pesticide demeton by Corynebacterium glutamicum
Peinado-Onsurbe_2000_Biol.Neonat_77_131 Effect of fasting on hepatic lipase activity in the liver of developing rats
Sendak_2000_J.Lipid.Res_41_260 Binding of hepatic lipase to heparin. Identification of specific heparin-binding residues in two distinct positive charge clusters
Estafan_2000_Am.J.Dent_13_192 Cavity wall adaptation of resin-based composites lined with flowable composites
Zhang_2000_Zhongguo.Zhong.Xi.Yi.Jie.He.Za.Zhi_20_43 [Experimental study on effect of bushen yijing recipe in delaying senility of bone and brain of aged male rats]
Takeuchi_2000_World.J.Gastroenterol_6_651 Stimulation by nizatidine, a histamine H(2)-receptor antagonist, of duodenal HCO(3)(-)secretion in rats:relation to anti-cholinesterase activity
Chen_2000_Sheng.Li.Xue.Bao_52_295 [Protective effect of exogenous glial cell line derived neurotrophic factor on neurons after sciatic nerve injury in rats]
Kivela_2000_Duodecim_116_1016 [Lice and crab lice in the eye lashes]
Laine_2000_Duodecim_116_1620 [Toxic syndromes that accompany poisonings]
Lindahl_2000_J.Mol.Biol_295_613 Identification of related proteins on family, superfamily and fold level
Smith_2000_Biochem.Educ_28_76 How do proteins fold?
Sulkava_2000_Duodecim_116_2867 [Drug therapy of Alzheimer's disease]
Cowles_2000_J.Bacteriol_182_6339 BenR, a XylS homologue, regulates three different pathways of aromatic acid degradation in Pseudomonas putida.
Carbonell_2000_Mol.Divers_5_131 Identification of selective inhibitors of acetylcholinesterase from a combinatorial library of 2,5-piperazinediones
Russell_2000_Exp.Parasitol_96_222 Nippostrongylus brasiliensis: infection induces upregulation of acetylcholinesterase activity on rat intestinal epithelial cells
Marques_2000_Biochem.Biophys.Res.Commun_279_832 A new subfamily of high molecular mass CDC2-related kinases with PITAI\/VRE motifs
Kassa_2000_Pharmacol.Biochem.Behav_67_663 Neuroprotective effects of currently used antidotes in soman-poisoned rats
Skjerve_2000_Int.J.Geriatr.Psychiatry_15_1147 Improvement in sundowning in dementia with Lewy bodies after treatment with donepezil
Earl-Slater_2000_Clin.Perform.Qual.Health.Care_8_47 Donepezil and Alzheimer's dementia
Sramek_2000_Alzheimer.Dis.Assoc.Disord_14_216 RBC cholinesterase inhibition: a useful surrogate marker for cholinesterase inhibitor activity in Alzheimer disease therapy?
Robbins_2000_Science_290_2275 Neuroscience. Boosting working memory
Rowsey_2000_Auton.Neurosci_85_148 A peripheral mechanism of fever: differential sensitivity to the antipyretic action of methyl scopolamine
Li_2000_Pharmacogenet_10_767 Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds
Baladi_2000_Clin.Ther_22_1549 Rivastigmine for Alzheimer's disease: Canadian interpretation of intermediate outcome measures and cost implications
Felgenhauer_2000_J.Toxicol.Clin.Toxicol_38_803 Intoxication with huperzine A, a potent anticholinesterase found in the fir club moss
Hoshino_2000_Vis.Neurosci_17_893 Distribution of terminals from pedunculopontine tegmental nucleus and synaptic organization in lateralis medialis-suprageniculate nucleus of cat's thalamus: anterograde tracing, immunohistochemical studies, and quantitative analysis
Cuajungco_2000_Ann.N.Y.Acad.Sci_920_292 Metal chelation as a potential therapy for Alzheimer's disease
Giacobini_2000_Ann.N.Y.Acad.Sci_920_321 Cholinesterase inhibitors stabilize Alzheimer's disease
Takeda_2000_Nippon.Ronen.Igakkai.Zasshi_37_879 [Treatment of the elderly dementia patients]
Masuoka_2000_Rinsho.Ketsueki_41_1226 [Recovery from pancytopenia and liver dysfunction after administration of thiamazole for hyperthyroidism]
Diaz_2000_Ann.N.Y.Acad.Sci_916_628 Insecticide resistance studies on Blattella germanica (Dictyoptera:Blattellidae) from Cuba
Kuo_2000_Mol.Cell.Biochem_214_121 Protein nitration
McGirr_2000_Ulster.Med.J_69_123 Drugs for dementia: the first year. An audit of prescribing practice
Dunn_2000_J.Psychopharmacol_14_406 Adverse effects associated with the use of donepezil in general practice in England
Bradamante_2000_Coll.Antropol_24_373 Plasma cholinesterase activity in patients with uterine cervical cancer during radiotherapy
Clark_2000_Brain.Behav.Evol_56_235 Mammal-like striatal functions in Anolis. I. Distribution of serotonin receptor subtypes, and absence of striosome and matrix organization
Dumaswala_2000_Free.Radic.Res_33_517 Glutathione loading prevents free radical injury in red blood cells after storage
Galeotti_2000_Jpn.J.Pharmacol_84_418 Role of 5-HT1A receptors in a mouse passive avoidance paradigm
Inestrosa_2000_Acta.Neurol.Scand.Suppl_176_53 Acetylcholinesterase-amyloid-beta-peptide interaction and Wnt signaling involvement in Abeta neurotoxicity
Kanno_2000_Rinsho.Byori__21 [Investigative application of a laboratory database]
Kucheriavykh_2000_Ross.Fiziol.Zh.Im.I.M.Sechenova_86_1669 [Effects of acetylcholine and histamine on leukocyte and neutrophil numbers in the endometrium of rats in various phases of the estrous cycle (by imprints)]
Malik_2000_Fresenius.J.Anal.Chem_367_211 Capillary electrophoretic determination of dithiocarbamates and ethyl xanthate
Mason_2000_Hum.Exp.Toxicol_19_511 Rates of spontaneous reactivation and aging of acetylcholinesterase in human erythrocytes after inhibition by organophosphorus pesticides
Mori_2000_Nihon.Ronen.Igakkai.Zasshi_37_772 [Dementia with Lewy bodies]
Ocampo_2000_J.Am.Mosq.Control.Assoc_16_331 Insecticide susceptibility in Anopheles pseudopunctipennis from Colombia: comparison between bioassays and biochemical assays
Pennefather_2000_J.Auton.Pharmacol_20_193 The autonomic and sensory innervation of the smooth muscle of the prostate gland: a review of pharmacological and histological studies
Ragoucy-Sengler_2000_Hum.Exp.Toxicol_19_657 Aldicarb poisoning
Ravi_2000_Indian.J.Physiol.Pharmacol_44_473 Long-term effects of postnatal aluminium exposure on acetylcholinesterase activity and biogenic amine neurotransmitters in rat brain
Roshchina_2000_Ross.Fiziol.Zh.Im.I.M.Sechenova_86_1300 [Functions of neuromediators in plants]
Saez-Valero_2000_Acta.Neurol.Scand.Suppl_176_49 An unusually glycosylated form of acetylcholinesterase is a CSF biomarker for Alzheimer's disease
Semenova_2000_Ross.Fiziol.Zh.Im.I.M.Sechenova_86_1268 [Localization, kinetic parameters, and functions of cholinesterase of the starfish ampulla]
Sharifullina_2000_Ross.Fiziol.Zh.Im.I.M.Sechenova_86_1314 [Pre- and postsynaptic effects of the calcium channel blocker verapamil in the nerve-muscle preparation]
Sunami_2000_J.Toxicol.Sci_25_403 Evaluation of a 5-day Hershberger assay using young mature male rats: methyltestosterone and p,p'-DDE, but not fenitrothion, exhibited androgenic or antiandrogenic activity in vivo
Swiatkiewicz_2000_Folia.Biol.(Krakow)_48_97 The presence of acetylcholinesterase-positive nerve fibres in the deep pineal gland and the pineal stalk but not in the superficial part of adult albino rats
Vlahos_2000_J.Auton.Pharmacol_20_237 Influence of the epithelium on acetylcholine release from parasympathetic nerves of the rat trachea
Micic_2000_J.Alzheimers.Dis_2_1 Acetylcholinesterase Activity in the Mongolian Gerbil Brain after Acute Poisoning with Aluminum
Fujino_2000_J.Biochem.(Tokyo)_127_1087 Identification of the cleavage sites of oxidized protein that are susceptible to oxidized protein hydrolase (OPH) in the primary and tertiary structures of the protein
White_2000_Mol.Microbiol_36_662 AglU, a protein required for gliding motility and spore maturation of Myxococcus xanthus, is related to WD-repeat proteins
Sieber_2000_Plant.Cell_12_721 Transgenic Arabidopsis plants expressing a fungal cutinase show alterations in the structure and properties of the cuticle and postgenital organ fusions
Bandmann_2000_J.Biotechnol_79_161 Genetic engineering of the Fusarium solani pisi lipase cutinase for enhanced partitioning in PEG-phosphate aqueous two-phase systems
van Mierlo_2000_J.Biotechnol_79_281 Protein folding and stability investigated by fluorescence, circular dichroism (CD), and nuclear magnetic resonance (NMR) spectroscopy: the flavodoxin story
Fett_2000_Lett.Appl.Microbiol_31_25 Production of cutinolytic esterase by filamentous bacteria
Melo_2000_Chem.Phys.Lipids_106_181 Dynamic light scattering of cutinase in AOT reverse micelles
Carvalho_2000_J.Biotechnol_81_1 Kinetics of cutinase catalyzed transesterification in AOT reversed micelles: modeling of a batch stirred tank reactor
Goncalves_2000_Biochim.Biophys.Acta_1480_92 Effects of ionic surfactants used in reversed micelles on cutinase activity and stability
Berggren_2000_Biochim.Biophys.Acta_1481_317 Substitutions of surface amino acid residues of cutinase probed by aqueous two-phase partitioning
Sagt_2000_Appl.Environ.Microbiol_66_4940 Introduction of an N-glycosylation site increases secretion of heterologous proteins in yeasts
Baptista_2000_Biotechnol.Bioeng_70_699 Trehalose delays the reversible but not the irreversible thermal denaturation of cutinase
Egmond_2000_Biochimie_82_1015 Fusarium solani pisi cutinase
Fojan_2000_Biochimie_82_1033 What distinguishes an esterase from a lipase: a novel structural approach
Svendsen_2000_Biochim.Biophys.Acta_1543_223 Lipase protein engineering
Cunha_2000_Bioseparation_9_203 Effect of salts and surfactants on the partitioning of Fusarium solani pisi cutinase in aqueous two-phase systems of thermoseparating ethylene oxide\/propylene oxide random copolymer and hydroxypropyl starch
Costa_2000_Bioseparation_9_231 Scale-up of recombinant cutinase recovery by whole broth extraction with PEG-phosphate aqueous two-phase
Rodenbrock_2000_Bioseparation_9_269 Extraction of peptide tagged cutinase in detergent-based aqueous two-phase systems
Sucgang_2000_J.Eukaryot.Microbiol_47_334 Toward the functional analysis of the Dictyostelium discoideum genome
Lo_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_756 Crystallization and preliminary X-ray crystallographic analysis of thioesterase I from Escherichia coli
Kobayashi_2000_FEMS.Microbiol.Lett_188_165 Accumulation of an artificial cell wall-binding lipase by Bacillus subtilis wprA and\/or sigD mutants
Chahinian_2000_Curr.Protein.Pept.Sci_1_91 The C-terminal domain of pancreatic lipase: functional and structural analogies with c2 domains
Wu_2000_Hunan.Yi.Ke.Da.Xue.Xue.Bao_25_529 [Innervation of medial olivocochlear efferents in the cochlea of gerbils]
Chen_2000_Zhongguo.Xiu.Fu.Chong.Jian.Wai.Ke.Za.Zhi_14_343 [Protective effect of tumor necrosis factor-alpha on motor neurons after peripheral nerve injury]
Lin_2000_Bioorg.Med.Chem_8_2601 Quantitative structure-activity relationships for the pre-steady-state inhibition of cholesterol esterase by 4-nitrophenyl-N-substituted carbamates
Bhattacharya_2000_Indian.J.Exp.Biol_38_753 Signal transduction by xenobiotics in fish
Liao_2000_Zhongguo.Shi.Yan.Xue.Ye.Xue.Za.Zhi_8_192 [Expression of the Cholinesterase-Related Cell Division Controller Gene in Peripheral Blood Cell from Patients with Myelodysplastic Syndrome]
Ffrench-Constant_2000_Appl.Environ.Microbiol_66_3310 A genomic sample sequence of the entomopathogenic bacterium Photorhabdus luminescens W14: potential implications for virulence
Ohnishi_2000_Syst.Appl.Microbiol_23_315 Comparative analysis of the whole set of rRNA operons between an enterohemorrhagic Escherichia coli O157:H7 Sakai strain and an Escherichia coli K-12 strain MG1655
Bowman_2000_Microbes.Infect_2_1479 Assessing the impact of Plasmodium falciparum genome sequencing
Ahren_2000_Eur.J.Pharmacol_404_239 Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice
Chandler_2000_Neuromuscul.Disord_10_584 Hereditary motor and sensory neuropathy--Lom (HMSNL): refined genetic mapping in Romani (Gypsy) families from several European countries
Liu_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_900 Expression, purification and preliminary crystallographic studies of a hyperthermophilic esterase from Archaeoglobus fulgidus
Roman_2000_Drugs.Today.(Barc)_36_641 Perspectives in the treatment of vascular dementia
Abraham_2000_J.Neuroendocrinol_12_486 Chronic corticosterone administration dose-dependently modulates Abeta(1-42)- and NMDA-induced neurodegeneration in rat magnocellular nucleus basalis
Adams_2000_J.Neuroendocrinol_12_Autho Adams T#S New pharmacological treatments for Alzheimer's disease: implications for dementia care nursing
Alonso-Villalobos_2000_J.Vet.Med.B.Infect.Dis.Vet.Public.Health_47_1 The in vitro secretion of acetylcholinesterase by adult stages of Heligmosomoides polygyrus: the effects of broad-spectrum anthelmintics
Aschner_2000_Neurotoxicol_21_175 Interactions between pesticides and glia: an unexplored experimental field
Barton_2000_Semin.Neurol_20_7 Ocular aspects of myasthenia gravis
Bazin_2000_Presse.Med_29_871 [Alzheimer type dementia: is early diagnosis significant?]
Bigbee_2000_Brain.Res_861_354 Evidence for the direct role of acetylcholinesterase in neurite outgrowth in primary dorsal root ganglion neurons
Birks_2000_Cochrane.Database.Syst.Rev__CD001191 Rivastigmine for Alzheimer's disease
Boucher_2000_Gene_247_145 Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2
Boudreau-Lariviere_2000_J.Neurochem_74_2250 Molecular mechanisms underlying the activity-linked alterations in acetylcholinesterase mRNAs in developing versus adult rat skeletal muscles
Braida_2000_Neuroreport_11_2025 Cannabinoid-induced working memory impairment is reversed by a second generation cholinesterase inhibitor in rats
Braida_2000_Pharmacol.Res_41_671 Excitatory and inhibitory effects of second-generation cholinesterase inhibitors on rat gastrointestinal transit
Britt_2000_Comp.Med_50_133 Histopathologic changes in the brain, heart, and skeletal muscle of rhesus macaques, ten days after exposure to soman (an organophosphorus nerve agent)
Bronfman_2000_Neurobiol.Dis_7_152 Acetylcholinesterase-positive fiber deafferentation and cell shrinkage in the septohippocampal pathway of aged amyloid precursor protein london mutant transgenic mice
Bronfman_2000_Neurosci_97_411 No evidence for cholinergic problems in apolipoprotein E knockout and apolipoprotein E4 transgenic mice
Cacabelos_2000_Drugs.Today.(Barc)_36_415 Pharmacological treatment of Alzheimer disease: from psychotropic drugs and cholinesterase inhibitors to pharmacogenomics
Cajaraville_2000_Sci.Total.Environ_247_295 The use of biomarkers to assess the impact of pollution in coastal environments of the Iberian Peninsula: a practical approach
Carcenac_2000_Presse.Med_29_992 [Extra-pyramidal syndrome induced by donepezil]
Cartaud_2000_Microsc.Res.Tech_49_73 The torpedo electrocyte: a model system to study membrane-cytoskeleton interactions at the postsynaptic membrane
Cavallotti_2000_Ann.Anat_182_243 Acetylcholinesterase activity in rat thymus after immunostimulation with interleukin beta
Chijiiwa_2000_Am.J.Surg_179_161 Biliary indocyanine green excretion as a predictor of hepatic adenosine triphosphate levels in patients with obstructive jaundice
Chiodera_2000_J.Investig.Med_48_203 Effect of aging on the arginine-vasopressin response to physostigmine and angiotensin II in normal men
Choe_2000_Nucl.Med.Biol_27_263 Syntheses and biological evaluation of (18)F-labeled 3-(1-benzyl-piperidin-4-yl)-1-(1-methyl-1H-indol-3-yl)propan-1-ones for in vivo mapping of acetylcholinesterase
Chuang_2000_Chang.Gung.Med.J_23_80 Experience in the treatment of myasthenia gravis with double filtration plasmapheresis
Cicardi_2000_J.Viral.Hepat_7_138 Prevalence and risk factors for the presence of serum cryoglobulins in patients with chronic hepatitis C
Cooper_2000_J.Neuroophthalmol_20_5 Accommodative and vergence findings in ocular myasthenia: a case analysis
Crumpton_2000_Brain.Res.Dev.Brain.Res_121_189 Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?
Csillik_2000_Neurotoxicol_21_343 Effect of the pesticide Deltamethrin on the Mauthner cells of Lake Balaton fish
Dam_2000_Brain.Res.Dev.Brain.Res_121_179 Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity
Delfini_2000_J.Magn.Reson_144_129 1H NMR relaxation investigation of inhibitors interacting with Torpedo californica acetylcholinesterase
Dooley_2000_Drugs.Aging_16_199 Donepezil: a review of its use in Alzheimer's disease
Doretti_2000_Enzyme.Microb.Technol_27_279 Acetylcholine biosensor involving entrapment of acetylcholinesterase and poly(ethylene glycol)-modified choline oxidase in a poly(vinyl alcohol) cryogel membrane
Dringenberg_2000_Neurobiol.Aging_21_135 Effect of tacrine on EEG slowing in the rat: enhancement by concurrent monoamine therapy
Durliat_2000_Eur.J.Biochem_267_549 Conserved protein motifs and structural organization of a fish gene homologous to mammalian apolipoprotein E
Duthoit_2000_Endocrinology_141_2518 Production of immunoreactive thyroglobulin C-terminal fragments during thyroid hormone synthesis
Ebert_2000_Clin.Pharmacol.Ther_67_538 Physostigmine reversal of midazolam-induced electroencephalographic changes in healthy subjects
Egashira_2000_Nihon.Ronen.Igakkai.Zasshi_37_233 [Effects of breeding conditions on neurochemical cholinergic and monoaminergic markers in aged rat brain]
Emilien_2000_Arch.Neurol_57_454 Prospects for pharmacological intervention in Alzheimer disease
Eskenasy_2000_Somatosens.Mot.Res_17_123 Hierarchy within human SI: supporting data from cytochrome oxidase, acetylcholinesterase and NADPH-diaphorase staining patterns
Farlow_2000_Dement.Geriatr.Cogn.Disord_11_202 Metrifonate therapy in Alzheimer's disease: a pooled analysis of four randomized, double-blind, placebo-controlled trials
Fillit_2000_Manag.Care.Interface_13_51 Practice guidelines for the diagnosis and treatment of Alzheimer's disease in a managed care setting: Part II--Pharmacologic therapy. Alzheimer's Disease (AD) Managed Care Advisory Council
Forstl_2000_Alzheimer.Dis.Assoc.Disord_14 Suppl 1_S103 Clinical issues in current drug therapy for dementia
Fujii_2000_Can.J.Physiol.Pharmacol_78_392 Enhancement of hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by repeated lithium treatment in rats
Fujimoto_2000_Alcohol.Clin.Exp.Res_24_48S Plasma endotoxin and serum cytokine levels in patients with alcoholic hepatitis: relation to severity of liver disturbance
Furlong_2000_Neurotoxicol_21_91 Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1)
Fylkesnes_2000_Tidsskr.Nor.Laegeforen_120_905 [Dementia and hypothyroidism]
Geen_2000_J.Neurol.Sci_176_37 Autoantibodies to acetylcholinesterase revisited
Gelinas_2000_J.Geriatr.Psychiatry.Neurol_13_9 Metrifonate enhances the ability of Alzheimer's disease patients to initiate, organize, and execute instrumental and basic activities of daily living
Giacobini_2000_Alzheimer.Dis.Assoc.Disord_14 Suppl 1_S3 Cholinesterase inhibitor therapy stabilizes symptoms of Alzheimer disease
Gordon_2000_Toxicology_146_1 Prolonged elevation in blood pressure in the unrestrained rat exposed to chlorpyrifos
Guilhermino_2000_Sci.Total.Environ_247_137 In vitro and in vivo inhibition of Daphnia magna acetylcholinesterase by surfactant agents: possible implications for contamination biomonitoring
Haas_2000_Neurosci_97_25 Entorhinal cortex lesion does not alter reelin messenger RNA expression in the dentate gyrus of young and adult rats
Hanson_2000_Cleve.Clin.J.Med_67_441 Effective treatment of Alzheimer disease and its complications
Harkany_2000_Ann.N.Y.Acad.Sci_903_374 beta-Amyloid excitotoxicity in rat magnocellular nucleus basalis. Effect of cortical deafferentation on cerebral blood flow regulation and implications for Alzheimer's disease
Hauber_2000_Clin.Ther_22_439 Savings in the cost of caring for patients with Alzheimer's disease in Canada: an analysis of treatment with rivastigmine
Hayes_2000_Neurosci.Lett_287_146 Human rotation-mediated fetal mixed brain cell aggregate culture: characterization and N-methyl-D-aspartate toxicity
Heo_2000_Mol.Cells_10_253 Inhibitory effect of Artemisia asiatica alkaloids on acetylcholinesterase activity from rat PC12 cells
Hewitt_2000_Drug.Metab.Dispos_28_755 Metabolism of fluroxypyr, fluroxypyr methyl ester, and the herbicide fluroxypyr methylheptyl ester. II: in rat skin homogenates
Hill_2000_Toxicon_38_1663 Characterization of venom (Duvernoy's secretion) from twelve species of colubrid snakes and partial sequence of four venom proteins
Hock_2000_Praxis.(Bern.1994)_89_529 [Alzheimer dementia]
Hoffmann_2000_J.Clin.Endocrinol.Metab_85_4795 Type I hyperlipoproteinemia due to a novel loss of function mutation of lipoprotein lipase, Cys(239)-->\;Trp, associated with recurrent severe pancreatitis
Homma_2000_Alzheimer.Dis.Assoc.Disord_14 Suppl 1_S123 Current status of clinical trials for Alzheimer-type dementia in Japan: strategies to facilitate the development of antidementia drugs
Iannaccone_2000_Muscle.Nerve_23_1129 Congenital myasthenic syndrome with sleep hypoventilation
Ikarashi_2000_J.Chromatogr.B.Biomed.Sci.Appl_742_295 Effect of 2-deoxy-D-glucose on acetylcholine and histamine levels in gastric juice of pylorus-ligated rats anesthetized with urethane
Ingkaninan_2000_J.Chromatogr.A_872_61 High-performance liquid chromatography with on-line coupled UV, mass spectrometric and biochemical detection for identification of acetylcholinesterase inhibitors from natural products
Ingkaninan_2000_J.Nat.Prod_63_803 The application of HPLC with on-line coupled UV\/MS-biochemical detection for isolation of an acetylcholinesterase inhibitor from narcissus 'Sir Winston Churchill'
Jett_2000_Neurotoxicol_21_141 In vitro and in vivo effects of chlorpyrifos on glutathione peroxidase and catalase in developing rat brain
Jeyarasasingam_2000_Neuroreport_11_1173 Tacrine, a reversible acetylcholinesterase inhibitor, induces myopathy
Ji_2000_Anat.Rec_259_86 Intrinsic interrelation of lymphatic endothelia with nerve elements in the monkey urinary bladder
Johnson_2000_Appl.Biochem.Biotechnol_83_131 Localization of a novel adhesion-promoting site on acetylcholinesterase using catalytic antiacetylcholinesterase antibodies displaying cholinesterase-like activity
Jonas_2000_Biochim.Biophys.Acta_1529_245 Lecithin cholesterol acyltransferase
Jung_2000_Neurosci_97_495 Targeted disruption of the dopamine D(2) and D(3) receptor genes leads to different alterations in the expression of striatal calbindin-D(28k)
Karlsson_2000_Protein.Expr.Purif_18_286 Expression, purification, and characterization of histidine-tagged mouse monoglyceride lipase from baculovirus-infected insect cells
Kawashima_2000_Pharmacol.Ther_86_29 Extraneuronal cholinergic system in lymphocytes
Keifer_2000_Am.J.Prev.Med_18_80 Effectiveness of interventions in reducing pesticide overexposure and poisonings
Khurana_2000_Arch.Neurol_57_600 Organophosphorus intoxication
Klichkhanov_2000_Biull.Eksp.Biol.Med_129_326 [Temperature-dependent activity of acetylcholinesterase in synaptic membranes from the rat brain during hypothermia]
Kluchova_2000_Bratisl.Lek.Listy_101_18 [Coexistence of cholinergic and nitrergic neurotransmitters in the spinal cord of rabbits]
Kluchova_2000_Physiol.Res_49_151 Partial colocalization of NADPH-diaphorase and acetylcholinesterase positivity in spinal cord neurons
Knott_2000_Neuropsychobiology_41_210 Acute nicotine administration in Alzheimer's disease: an exploratory EEG study
Knott_2000_Methods.Find.Exp.Clin.Pharmacol_22_115 Pharmaco-EEG test dose response predicts cholinesterase inhibitor treatment outcome in Alzheimer's disease
Koutcherov_2000_J.Comp.Neurol_423_299 Organization of the human paraventricular hypothalamic nucleus
Kretzschmar_2000_Anaesthesiol.Reanim_25_37 [Initiation of lipid peroxidation (LPO) in blood during intraoperative mechanical autotransfusion--is hepatotoxicity of lipid peroxidation products of clinical significance?]
Krieger_2000_Arch.Environ.Contam.Toxicol_38_546 Malathion deposition, metabolite clearance, and cholinesterase status of date dusters and harvesters in California
Kronman_2000_J.Biol.Chem_275_29488 Hierarchy of post-translational modifications involved in the circulatory longevity of glycoproteins. Demonstration of concerted contributions of glycan sialylation and subunit assembly to the pharmacokinetic behavior of bovine acetylcholinesterase
Lanctot_2000_Int.J.Geriatr.Psychiatry_15_338 Donepezil for behavioural disorders associated with Lewy bodies: a case series
Lee_2000_Med.Vet.Entomol_14_11 Biochemical characterization of insecticide resistance in the German cockroach, Blattella germanica, from Malaysia
Legay_2000_Microsc.Res.Tech_49_56 Why so many forms of acetylcholinesterase?
Lev-Lehman_2000_J.Mol.Neurosci_14_93 Synaptogenesis and myopathy under acetylcholinesterase overexpression
Lintern_2000_Neurosci.Lett_284_101 Effect of halothane administration on acetylcholinesterase activity in guinea-pig muscle and brain
Liu_2000_Neurotoxicol.Teratol_22_389 Effects of cholinesterase inhibitors on a two-component chained schedule performance in rats
Loftus_2000_Science_288_2379 Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
Lutz_2000_Br.J.Plast.Surg_53_149 Selection of donor nerves--an important factor in end-to-side neurorrhaphy
Maelicke_2000_Eur.J.Pharmacol_393_165 Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease
Maheut-Lourmiere_2000_Neurochirurgie_46_117 [Hydrocephalus during pregnancy with or without neurosurgical history in childhood. Practical advice for management]
Marguet_2000_Proc.Natl.Acad.Sci.U.S.A_97_6874 Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26
Martinez_2000_Bioorg.Med.Chem_8_731 Lipase-catalysed synthesis of new acetylcholinesterase inhibitors: N-benzylpiperidine aminoacid derivatives
Maurissen_2000_Neurotoxicol.Teratol_22_237 Chlorpyrifos: lack of cognitive effects in adult Long-Evans rats
McKeand_2000_Parasitol_120 Suppl_S17 Vaccine development and diagnostics of Dictyocaulus viviparus
McKeith_2000_Int.J.Geriatr.Psychiatry_15_387 Rivastigmine in the treatment of dementia with Lewy bodies: preliminary findings from an open trial
Meyer_2000_Keio.J.Med_49 Suppl 1_A95 XE-CT CBF changes during normative aging, cognitive decline and dementia
Mizuno_2000_Epilepsy.Res_40_187 Effects of carbamazepine on acetylcholine release and metabolism
Monnet-Tschudi_2000_Toxicol.Appl.Pharmacol_165_175 Maturation-dependent effects of chlorpyrifos and parathion and their oxygen analogs on acetylcholinesterase and neuronal and glial markers in aggregating brain cell cultures
Moon_2000_Bioorg.Med.Chem.Lett_10_1435 Synthesis of tetrakis(multifluoro-4-pyridyl)porphin derivatives as acetylcholinesterase inhibitors
Mora_2000_Ecotoxicol.Environ.Saf_46_234 Relationship between toxicokinetics of carbaryl and effect on acetylcholinesterase activity in Pomacea patula snail
Mukhtarov_2000_Ross.Fiziol.Zh.Im.I.M.Sechenova_86_335 [Modulation of the intensity of the non-quantal transmitter release by nitric oxide (NO) at the neuromuscular junction]
Navaratnam_2000_J.Neurochem_74_2146 Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization
Nguyen_2000_J.Dent.Res_79_939 Choline acetyltransferase, acetylcholinesterase, and nicotinic acetylcholine receptors of human gingival and esophageal epithelia
Nigg_2000_Rev.Environ.Contam.Toxicol_163_29 Blood cholinesterases as human biomarkers of organophosphorus pesticide exposure
Obata_2000_Bioorg.Med.Chem.Lett_10_1315 Synthetic conversion of ACAT inhibitor to acetylcholinesterase inhibitor
Ohayo-Mitoko_2000_Occup.Environ.Med_57_195 Self reported symptoms and inhibition of acetylcholinesterase activity among Kenyan agricultural workers
Ohi_2000_Scand.J.Gastroenterol_35_413 Tissue concentration of platelet-derived endothelial cell growth factor in colorectal cancer
Oliveira-Silva_2000_Hum.Exp.Toxicol_19_173 Cholinesterase activities determination in frozen blood samples: an improvement to the occupational monitoring in developing countries
Oue_2000_Pediatr.Surg.Int_16_267 Muscarinic acetylcholine receptor expression in aganglionic bowel
Overstreet_2000_Neurotoxicol_21_75 Organophosphate pesticides, cholinergic function and cognitive performance in advanced age
Packard_2000_N.Engl.J.Med_343_1148 Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group
Pakaski_2000_Brain.Res_863_266 In vitro effects of metrifonate on neuronal amyloid precursor protein processing and protein kinase C level
Park_2000_Biochem.Biophys.Res.Commun_276_321 Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells
Parker_2000_Arch.Environ.Contam.Toxicol_39_233 Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris)
Parnetti_2000_J.Neurol_247_163 Therapeutic options in dementia
Pautas_2000_Presse.Med_29_835 [Myasthenia in the aged: a case with unusually late onset]
Perry_2000_Eur.J.Pharmacol_393_215 Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases
Platteborze_2000_Biotechnol.Appl.Biochem_31 ( Pt 3)_225 Expression of biologically active human butyrylcholinesterase in the cabbage looper (Trichoplusia ni)
Radtke-Schuller_2000_J.Comp.Neurol_423_687 Olfactory bulb and retrobulbar regions in the hedgehog tenrec: organization and interconnections
Raskind_2000_Neurology_54_2261 Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group
Recanatini_2000_J.Med.Chem_43_2007 SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues
Reiner_2000_Brain.Behav.Evol_55_26 Succinic dehydrogenase histochemistry reveals the location of the putative primary visual and auditory areas within the dorsal ventricular ridge of Sphenodon punctatus
Ricciardi_2000_J.Biol.Chem_275_18302 Do structural deviations between toxins adopting the same fold reflect functional differences?
Rodriguez-Franco_2000_Arch.Pharm.(Weinheim)_333_118 Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties
Rollino_2000_Artif.Organs_24_386 Is vecuronium toxicity abolished by hemodialysis? A case report
Ruano_2000_Neurochem.Res_25_461 Changes of acetylcholinesterase activity in brain areas and liver of sucrose- and ethanol-fed rats
Sancho_2000_Ecotoxicol.Environ.Saf_46_57 Alterations on AChE activity of the fish Anguilla anguilla as response to herbicide-contaminated water
Sander_2000_Chemistry_6_1564 Enzymatic protecting group techniques for glyco- and phosphopeptide chemistry: synthesis of a glycophosphopeptide from human serum response factor
Sarkar_2000_J.Reprod.Fertil_118_29 Effects of an organophosphate pesticide, quinalphos, on the hypothalamo-pituitary-gonadal axis in adult male rats
Saroff_2000_Neuroreport_11_1117 Selective vulnerability of spinal cord motor neurons to non-NMDA toxicity
Schredl_2000_Exp.Gerontol_35_243 The effect of rivastigmine on sleep in elderly healthy subjects
Seed_2000_Anaesthesia_55_574 Anaphylaxis caused by neostigmine
Shapira_2000_Isr.Med.Assoc.J_2_470 Genomic and transcriptional characterization of the human ACHE locus: complex involvement with acquired and inherited diseases
Sherwin_2000_J.Am.Geriatr.Soc_48_431 Mild cognitive impairment: potential pharmacological treatment options
Shinotoh_2000_Alzheimer.Dis.Assoc.Disord_14 Suppl 1_S114 Brain acetylcholinesterase activity in Alzheimer disease measured by positron emission tomography
Shu_2000_Neurochem.Res_25_231 A new subdivision, marginal division, in the neostriatum of the monkey brain
Singh_2000_Int.J.Clin.Pharmacol.Ther_38_315 Aspirin esterases in North-West Indians: the influence of age and nutrition
Smialowski-Fleter_2000_Eur.J.Biochem_267_2227 Structure-function relationships in the carboxylic-ester-hydrolase superfamily. Disulfide bridge arrangement in porcine intestinal glycerol-ester hydrolase
Sorger_2000_Nucl.Med.Biol_27_23 In vivo [125I]-iodobenzovesamicol binding reflects cortical cholinergic deficiency induced by specific immunolesion of rat basal forebrain cholinergic system
Sternfeld_2000_Proc.Natl.Acad.Sci.U.S.A_97_8647 Excess read-through acetylcholinesterase attenuates but the synaptic variant intensifies neurodeterioration correlates
Sun_2000_Arch.Oral.Biol_45_621 Effects of low concentrations of paraoxon on Ca(2+) mobilization in a human parotid salivary cell-line HSY
Szlendak_2000_Exp.Appl.Acarol_24_45 Pirimiphos-methyl resistance in two stored product mites, Acarus siro and Acarus farris, as detected by impregnated paper bioassay and esterase activity assays
Takiguchi_2000_J.Hum.Genet_45_200 Structural and functional study of K453E mutant protective protein\/cathepsin A causing the late infantile form of galactosialidosis
Tojima_2000_Neurosci.Res_37_153 Acquisition of neuronal proteins during differentiation of NG108-15 cells
Toth_2000_Electromyogr.Clin.Neurophysiol_40_17 The diagnostic value of stapedius reflex and stapedius reflex exhaustion in myasthenia gravis
Trabace_2000_Brain.Res_865_268 In vivo neurochemical effects of the acetylcholinesterase inhibitor ENA713 in rat hippocampus
Trevisani_2000_Dis.Colon.Rectum_43_599 Neostigmine: safe and effective treatment for acute colonic pseudo-obstruction
Tsakiris_2000_Clin.Biochem_33_103 Protective effect of L-phenylalanine on rat brain acetylcholinesterase inhibition induced by free radicals
Tsugawa_2000_Appl.Biochem.Biotechnol_84-86_311 Improvement of enantioselectivity of chiral organophosphate insecticide hydrolysis by bacterial phosphotriesterase
Tumiatti_2000_Bioorg.Med.Chem_8_681 [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]-trimethylammonium (McN-A-343)-related compounds. Effect of the butynyl chain inclusion into an aromatic unit on the potency for muscarinic receptors
VanDenBerg_2000_Drugs.Aging_16_123 Cholinesterase inhibitors for the treatment of Alzheimer's disease in the elderly
Wan_2000_Neurosci.Lett_288_81 The promoter of human acetylcholinesterase is activated by a cyclic adenosine 3',5'-monophosphate-dependent pathway in cultured NG108-15 neuroblastoma cells
Wang_2000_Eur.J.Pharmacol_398_65 Huperzine A improves cognitive deficits caused by chronic cerebral hypoperfusion in rats
Ward_2000_Neurobiol.Aging_21_125 Cholinergic medial septum neurons do not degenerate in aged 129\/Sv control or p75(NGFR)-\/-mice
Wei_2000_Biochem.Pharmacol_60_121 High-level expression of human butyrylcholinesterase gene in Bombyx mori and biochemical-pharmacological characteristic study of its product
Wettstein_2000_Phytomedicine_6_393 Cholinesterase inhibitors and Gingko extracts--are they comparable in the treatment of dementia? Comparison of published placebo-controlled efficacy studies of at least six months' duration
Worek_2000_Arch.Toxicol_74_21 Effect of human plasma on the reactivation of sarin-inhibited human erythrocyte acetylcholinesterase
Wu_2000_J.Comp.Neurol_423_140 Converging evidence from microstimulation, architecture, and connections for multiple motor areas in the frontal and cingulate cortex of prosimian primates
Xiao_2000_Neurosci.Lett_286_155 Protective effects of huperzine A on beta-amyloid(25-35) induced oxidative injury in rat pheochromocytoma cells
Ye_2000_Biochim.Biophys.Acta_1493_373 Identification of a novel FAS\/ER-alpha fusion transcript expressed in human cancer cells
Zabinski_2000_Toxicol.Ind.Health_16_58 The activity of erythrocyte enzymes and basic indices of peripheral blood erythrocytes from workers chronically exposed to mercury vapours
Zhang_2000_Brain.Res_868_157 Epitopes of human brain acetylcholinesterase
Zheng_2000_Hear.Res_143_115 Metabolism of the dorsal cochlear nucleus in rat brain slices
Zheng_2000_Toxicol.Sci_55_124 Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats
Zhong_2000_Neurogenetics_3_41 CLN-encoded proteins do not interact with each other
Aparicio_2000_Trends.Genet_16_54 Vertebrate evolution: recent perspectives from fish
Cotman_2000_Mol.Cell.Neurosci_15_183 Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brain
Higashijima_2000_J.Neurosci_20_206 Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter\/enhancer
Holley_2000_Curr.Top.Dev.Biol_47_247 Somitogenesis in zebrafish
Legendre_2000_J.Neurosci_20_140 Recovery from open channel block by acetylcholine during neuromuscular transmission in zebrafish
Li_2000_Dev.Biol_217_394 Double-stranded RNA injection produces null phenotypes in zebrafish
Mega_2000_J.Neuropsychiatry.Clin.Neurosci_12_209 Orbital and dorsolateral frontal perfusion defect associated with behavioral response to cholinesterase inhibitor therapy in Alzheimer's disease
Nguyen_2000_Development_127_1209 Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway
Scaps_2000_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_125_377 Acetylcholinesterase activity of the polychaete Nereis diversicolor: effects of temperature and salinity
Spassova_2000_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_126_79 Acute effects of acephate and methamidophos on acetylcholinesterase activity, endocrine system and amino acid concentrations in rats
Verhage_2000_Science_287_864 Synaptic assembly of the brain in the absence of neurotransmitter secretion
Durbin_2000_Development_127_1703 Anteroposterior patterning is required within segments for somite boundary formation in developing zebrafish
de Martino_2000_Dev.Dyn_217_279 Expression of sox11 gene duplicates in zebrafish suggests the reciprocal loss of ancestral gene expression patterns in development
Naruse_2000_Genetics_154_1773 A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution
Talbot_2000_Genes.Dev_14_755 Zebrafish mutations and functional analysis of the vertebrate genome
Blader_2000_Hum.Mol.Genet_9_945 Zebrafish developmental genetics and central nervous system development
Barresi_2000_Development_127_2189 The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity
Smith_2000_Gene_247_119 Identification and analysis of two snail genes in the pufferfish (Fugu rubripes) and mapping of human SNA to 20q
Mallouk_2000_Proc.Natl.Acad.Sci.U.S.A_97_4950 Elevated subsarcolemmal Ca2+ in mdx mouse skeletal muscle fibers detected with Ca2+-activated K+ channels
Imai_2000_Genetics_155_261 Analysis of chromosomal rearrangements induced by postmeiotic mutagenesis with ethylnitrosourea in zebrafish
Szewczyk_2000_J.Cell.Sci_113_2003 Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans
Beattie_2000_Development_127_2653 Mutations in the stumpy gene reveal intermediate targets for zebrafish motor axons
Bass_2000_Cell_101_235 Double-stranded RNA as a template for gene silencing
Cornell_2000_Development_127_2873 Delta signaling mediates segregation of neural crest and spinal sensory neurons from zebrafish lateral neural plate
Mundt-Petersen_2000_Exp.Neurol_164_112 Caspase inhibition increases embryonic striatal graft survival
Emre_2000_Eur.J.Neurol_7_247 Evidence-based pharmacological treatment of dementia
Rigaud_2000_Clin.Chem.Lab.Med_38_205 The apolipoprotein E epsilon4 allele and the response to tacrine therapy in Alzheimer's disease
Dieguez_1999_Rev.Cubana.Med.Trop_51_26 [Comparative analysis of resistance to insecticides in strains of Culex quinquefasciatus, from Camaguey]
de Blaquiere_2000_Toxicol.Appl.Pharmacol_166_81 Electrophysiological and biochemical effects of single and multiple doses of the organophosphate diazinon in the mouse
Quistad_2000_Chem.Res.Toxicol_13_652 Phosphoacetylcholinesterase: toxicity of phosphorus oxychloride to mammals and insects that can be attributed to selective phosphorylation of acetylcholinesterase by phosphorodichloridic acid
Suzuki_2000_Arch.Biochem.Biophys_379_344 Mechanism of selective release of membrane proteins from human erythrocytes in the presence of liposomes
Oates_2000_Dev.Biol_224_20 Too much interference: injection of double-stranded RNA has nonspecific effects in the zebrafish embryo
Furey_2000_Pharmacol.Biochem.Behav_66_475 Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans
Braginskaia_2000_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_100_29 [Certain biochemical blood markers in the process of cholinergic therapy in Alzheimer's disease]
Liu_2000_J.Econ.Entomol_93_667 Amplified esterases B1 and A2-B2 in field populations of Culex pipiens from China
Dunley_2000_Anal.Chem_72_2774 Correlated insecticide cross-resistance in azinphosmethyl resistant codling moth (Lepidoptera: Tortricidae)
Pauza_2000_Anat.Rec_259_353 Morphology, distribution, and variability of the epicardiac neural ganglionated subplexuses in the human heart
Gralewicz_2000_Acta.Neurobiol.Exp_60_203 Hyposensitivity to amphetamine following exposure to chlorphenvinphos--protection by amphetamine preexposure
Soreq_2000_Isr.Med.Assoc.J_2_81 Anti-sense approach to anticholinesterase therapeutics
Bornemann_2000_Ann.N.Y.Acad.Sci_908_260 Transgenic mouse models of Alzheimer's disease
Saltmarsh_2000_Bioorg.Med.Chem.Lett_10_1523 Synthesis of fluorescent probes directed to the active site gorge of acetylcholinesterase
Kassa_2000_Cas.Lek.Cesk_139_237 [Importance of reactivation of fosdrin-inhibited acetylcholinesterase in the brain and diaphragm for the in vivo therapeutic effect of oximes in rats poisoned with fosdrin]
Amador_2000_N.C.Med.J_61_209 Where we stand with treating dementia
Mohsin_2000_Biotechnol.Bioeng_69_591 Use of ion chromatography-electrospray mass spectrometry for the determination of ionic compounds in agricultural chemicals
Richins_2000_Indian.J.Physiol.Pharmacol_44_57 Expression, immobilization, and enzymatic characterization of cellulose-binding domain-organophosphorus hydrolase fusion enzymes
Gupta_2000_Hum.Exp.Toxicol_19_297 Cholinergic and noncholinergic brain biomarkers of insecticide exposure and effects
Kansal_2000_J.Control.Release_68_157 An observational study on neurobehavioural effects of acute oxydemeton-methyl (insecticide and acaricide) exposure in rats
Suzuki_2000_Biochemistry_39_9477 GPI-Linked proteins Do not transfer spontaneously from erythrocytes to liposomes. New aspects of reorganization of the cell membrane
Barnes_2000_Neurosci_99_17 Chronic treatment of old rats with donepezil or galantamine: effects on memory, hippocampal plasticity and nicotinic receptors
Bhattacharjee_2000_J.Mol.Recognit_13_213 Molecular similarity analysis between insect juvenile hormone and N, N-diethyl-m-toluamide (DEET) analogs may aid design of novel insect repellents
Das_2000_Pharmacol.Res_42_213 Immobilization stress-induced changes in brain acetylcholinesterase activity and cognitive function in mice
De Jaco_2000_J.Neurochem_75_1123 Modulation of acetylcholinesterase and voltage-gated Na(+) channels in choline acetyltransferase- transfected neuroblastoma clones
Deprez_2000_Biochem.J_350 Pt 1_283 Interaction of the collagen-like tail of asymmetric acetylcholinesterase with heparin depends on triple-helical conformation, sequence and stability
Frenzel_2000_J.Anal.Toxicol_24_365 Rapid multimethod for verification and determination of toxic pesticides in whole blood by means of capillary GC-MS
Fujii_2000_Neurosci.Lett_289_181 Effects of physostigmine and calcium on acetylcholine efflux from the hippocampus of freely moving rats as determined by in vivo microdialysis and a radioimmunoassay
Fujitani_2000_Food.Chem.Toxicol_38_617 Subchronic toxicity of chlorpropham (CIPC) in ICR mice
Giacobini_2000_J.Neural.Transm.Suppl_59_231 Present and future of Alzheimer therapy
Gorini_2000_Neurochem.Res_25_867 Effect of in vivo administration of naloxone on ATP-ase's enzyme systems of synaptic plasma membranes from rat cerebral cortex
Iannazzo_2000_Br.J.Pharmacol_130_2008 No involvement of nicotinic receptors in the facilitation of acetylcholine outflow in mouse cortex in the presence of neostigmine and atropine
Jones_2000_J.Pharmacol.Exp.Ther_294_1017 Muscarinic cholinergic modulation of prepulse inhibition of the acoustic startle reflex
Kamal_2000_Proc.Natl.Sci.Counc.Repub.China.B_24_108 Thermodynamic analysis of human retinal acetylcholinesterase inhibition using an anti-Alzheimer's drug, tacrine, through the development of a dual substrate and temperature model
Kamal_2000_J.Enzyme.Inhib_15_201 Dual substrate model for novel approach towards a kinetic study of acetylcholinesterase inhibition by diazinon
Kim_2000_Food.Addit.Contam_17_469 Determination of ethyl carbamate in some fermented Korean foods and beverages
Kolaczinski_2000_Bull.Entomol.Res_90_125 Experimental and molecular genetic analysis of the impact of pyrethroid and non-pyrethroid insecticide impregnated bednets for mosquito control in an area of pyrethroid resistance
Kolf-Clauw_2000_Vet.Hum.Toxicol_42_216 Acetyl- and pseudo-cholinesterase activities of plasma, erythrocytes, and whole blood in male beagle dogs using Ellman's assay
Krishnamoorthy_2000_Indian.J.Med.Res_111_81 Cost of mass annual single dose diethylcarbamazine distribution for the large scale control of lymphatic filariasis
Lee_2000_Biosens.Bioelectron_14_795 Rapid detection and identification of biological and chemical agents by immunoassay, gene probe assay and enzyme inhibition using a silicon-based biosensor
Maelicke_2000_Behav.Brain.Res_113_199 Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease
Miyo_2000_Genes.Genet.Syst_75_97 Seasonal fluctuation in susceptibility to insecticides within natural populations of Drosophila melanogaster: empirical observations of fitness costs of insecticide resistance
Motamed_2000_Anesth.Analg_91_732 The mechanism of pancuronium potentiation of mivacurium block: use of the isolated-arm technique
Nagymajtenyi_2000_Cent.Eur.J.Public.Health_8 Suppl_64 Experimentally induced functional changes of the nervous system caused by subchronic combined administration of heavy metals and an organophosphate pesticide
Nakazato_2000_Life.Sci_67_1139 Cholinergic and glutamatergic activation reverses working memory failure by hippocampal histamine H1 receptor blockade in rats
Nassar_2000_J.Egypt.Soc.Parasitol_30_631 Assessment of two natural marine toxins (Microcystis aeruginosa and Parasicyonis actinostoloides) for the control of some medical and agriculture insects with reference to the action on mice
Perrier_2000_J.Biol.Chem_275_34260 Two distinct proteins are associated with tetrameric acetylcholinesterase on the cell surface
Perry_2000_J.Pharm.Pharmacol_52_895 In-vitro inhibition of human erythrocyte acetylcholinesterase by salvia lavandulaefolia essential oil and constituent terpenes
Petroianu_2000_J.Appl.Toxicol_20_249 L-lactate protects in vitro acetylcholinesterase (AChE) from inhibition by paraoxon (E 600)
Robitzki_2000_Glia_31_195 Regulation of the rat oligodendroglia cell line OLN-93 by antisense transfection of butyrylcholinesterase
Sancho_2000_Rapid.Commun.Mass.Spectrom_14_1485 Direct determination of chlorpyrifos and its main metabolite 3,5, 6-trichloro-2-pyridinol in human serum and urine by coupled-column liquid chromatography\/electrospray-tandem mass spectrometry
Schetinger_2000_Neurochem.Res_25_949 New benzodiazepines alter acetylcholinesterase and ATPDase activities
Shinotoh_2000_Ann.Neurol_48_194 Progressive loss of cortical acetylcholinesterase activity in association with cognitive decline in Alzheimer's disease: a positron emission tomography study
Shohami_2000_J.Mol.Med.(Berl)_78_228 Antisense prevention of neuronal damages following head injury in mice
Srivastava_2000_Vet.Hum.Toxicol_42_212 Effect of diacetylmonoxime on blood enzymes in fenitrothion-dosed buffalo calves
Strnad_2000_Dtsch.Med.Wochenschr_125_835 [The pharmacotherapy of the cognitive disorders in Alzheimer's disease. Guidelines for rational drug use--a review]
Svensson_2000_Behav.Brain.Res_113_193 Tacrine interacts with different sites on nicotinic receptor subtypes in SH-SY5Y neuroblastoma and M10 cells
Takahashi_2000_Prostate_44_328 Low-dose staurosporine suppresses proliferation and induces neurites in human prostatic cancer TSU-Pr1 cells
Tessier_2000_Aquat.Toxicol_50_125 Anomalies on capture nets of Hydropsyche slossonae larvae (Trichoptera\; Hydropsychidae), a potential indicator of chronic toxicity of malathion (organophosphate insecticide)
Turski_2000_Pol.J.Pharmacol_52_63 Pilocarpine-induced seizures in rodents--17 years on
Windisch_2000_J.Neural.Transm.Suppl_59_301 Approach towards an integrative drug treatment of Alzheimer's disease
Woodruff-Pak_2000_Behav.Brain.Res_113_11 Nicotinic modulation in an animal model of a form of associative learning impaired in Alzheimer's disease
Xiao_2000_J.Neurosci.Res_61_564 Huperzine A and tacrine attenuate beta-amyloid peptide-induced oxidative injury
Zhang_2000_Neurosci.Lett_290_21 Effects of a traditional Chinese medicine, Qing Nao Yi Zhi Fang, on glutamate excitotoxicity in rat fetal cerebral neuronal cells in primary culture
Brown_2000_Handb.Exp.Pharmacol_144_3 The History of the Neuronal Nicotinic Receptors
Zoli_2000_Handb.Exp.Pharmacol_144_13 Distribution of Cholinergic Neurons in the Mammalian Brain with Special Reference to their Relationship with Neuronal Nicotinic Acetylcholine Receptors
Matter_2000_Handb.Exp.Pharmacol_144_33 Gene Structure and Transcriptional Regulation of the Neuronal Nicotinic Acetylcholine Receptors
Deneris_2000_Handb.Exp.Pharmacol_144_57 Transcriptional Regulation of Neuronal nAChR Subunit Genes
Taylor_2000_Handb.Exp.Pharmacol_144_79 Contributions of Studies of the Nicotinic Receptor from Muscle to Defining Structural and Functional Properties of Ligand-Gated Ion Channels
Lindstrom_2000_Handb.Exp.Pharmacol_144_101 The Structures of Neuronal Nicotinic Receptors
Sargent_2000_Handb.Exp.Pharmacol_144_163 The Distribution of Neuronal Nicotinic Acetylcholine Receptors
Kaiser_2000_Handb.Exp.Pharmacol_144_193 Presynaptic Neuronal Nicotinic Receptors: Pharmacology, Heterogeneity, and Cellular Mechanisms
Zoli_2000_Handb.Exp.Pharmacol_144_213 Neuronal Nicotinic Acetylcholine Receptors in Development and Aging
Berg_2000_Handb.Exp.Pharmacol_144_247 Nicotinic Acetylcholine Receptors in Ganglionic Transmission
Buisson_2000_Handb.Exp.Pharmacol_144_271 Neuronal Nicotinic Acetylcholine Receptors: From Biophysical Properties to Human Diseases
Francis_2000_Handb.Exp.Pharmacol_144_301 The Functional Diversity of Nicotinic Receptors in the Nervous System: Perspectives on Receptor Subtypes and Receptor Specialization
Albuquerque_2000_Handb.Exp.Pharmacol_144_337 Neuronal Nicotinic Receptors and Synaptic Transmission in the Mammalian Central Nervous System
Gotti_2000_Handb.Exp.Pharmacol_144_359 Properties of Heterologously and Lipid Bilayer Reconstituted Nicotinic Acetylcholine Receptors
Sivilotti_2000_Handb.Exp.Pharmacol_144_379 Comparison of Native and Recombinant Neuronal Nicotinic Receptors: Problems of Measurement and Expression
Arneric_2000_Handb.Exp.Pharmacol_144_419 Agonists and Antagonists of Nicotinic Acetylcholine Receptors
McIntosh_2000_Handb.Exp.Pharmacol_144_ Toxin Antagonists of the Neuronal Nicotinic Acetylcholine Receptor
Maelicke_2000_Handb.Exp.Pharmacol_144_477 Neuronal Nicotinic Acetylcholine Receptors in Non-neuronal Cells, Expression and Renaturation of Ligand Binding Domain, and Modulatory Control by Allosterically Acting Ligands
Gundelfinger_2000_Handb.Exp.Pharmacol_144_497 Insect Nicotinic Acetylcholine Receptors: Genes, Structure, Physiological and Pharmacological Properties
Marubio_2000_Handb.Exp.Pharmacol_144_525 Knockout Mice as Animal Models for Studying Nicotinic Acetylcholine Receptor Function
Nordberg_2000_Handb.Exp.Pharmacol_144_539 Noninvasive Exploration of Nicotinic Acetylcholine Receptors In Vivo
Stitzel_2000_Handb.Exp.Pharmacol_144_563 Genetic Regulation of Nicotine-Related Behaviors and Brain Nicotinic Receptors
Levin_2000_Handb.Exp.Pharmacol_144_587 The Role of Nicotinic Acetylcholine Receptors in Cognitive Function
Di Chiara_2000_Handb.Exp.Pharmacol_144_603 Behavioural Pharmacology and Neurobiology of Nicotine Reward and Dependence
Clementi_2000_Handb.Exp.Pharmacol_144_751 Involvement of Neuronal Nicotinic Receptors in Disease
Newhouse_2000_Handb.Exp.Pharmacol_144_779 Clinical Aspects of Nicotinic Agents: Therapeutic Applications in Central Nervous System Disorders
Abou-Hatab_2000_Arch.Gerontol.Geriatr_31_193 Plasma esterase activities in young and old patients undergoing open inguinal hernia repair
Adams_2000_J.Cell.Biol_150_1385 Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin
Aguera_2000_Analyst_125_1397 Splitless large-volume GC-MS injection for the analysis of organophosphorus and organochlorine pesticides in vegetables using a miniaturised ethyl acetate extraction
Ali_2000_J.Pharm.Pharmacol_52_1297 Effect of Rhazya stricta Decne on monoamine oxidase and cholinesterase activity and brain biogenic amine levels in rats
Alvarez-Arcaya_2000_Acta.Neurol.Scand_102_350 The butyrylcholinesterase K variant is a protective factor for sporadic Alzheimer's disease in women
Atoji_2000_Auton.Neurosci_84_1 Innervation of the pigeon oviduct: correlation of NADPH diaphorase with acetylcholinesterase, tyrosine hydroxylase, and neuropeptides
Atta_2000_J.Nat.Prod_63_1393 New norditerpenoid alkaloids from Aconitum falconeri
Bailey_2000_Arch.Toxicol_74_322 Association of azinphos-methyl with rat erythrocytes and hemoglobin
Birks_2000_Cochrane.Database.Syst.Rev__CD001190 Donepezil for mild and moderate Alzheimer's disease
Bomser_2000_J.Biochem.Mol.Toxicol_14_346 Activation of extracellular signal-regulated kinases (ERK 44\/42) by chlorpyrifos oxon in Chinese hamster ovary cells
Borgaonkar_2000_Dig.Dis.Sci_45_1644 Acute on chronic intestinal pseudoobstruction responds to neostigmine
Braida_2000_Pharmacol.Res_42_299 Eptastigmine improves eight-arm radial maze performance in aged rats
Bramich_2000_Auton.Neurosci_82_109 Potentiation by neostigmine of responses to vagal nerve stimulation in the sinus venosus of the toad
Bunc_2000_Pflugers.Arch_440_R173 In vivo effects of head-to-tail 3-alkylpiridinium polymers isolated from the marine sponge Raniera sarai
Burt_2000_Curr.Psychiatry.Rep_2_473 Donepezil and related cholinesterase inhibitors as mood and behavioral controlling agents
Camps_2000_J.Med.Chem_43_4657 New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease
Carpentier_2000_Neurotoxicol_21_521 Effects of atropine sulphate on seizure activity and brain damage produced by soman in guinea-pigs: ECoG correlates of neuropathology
Charpentier_2000_Anal.Biochem_285_76 A method to estimate acetylcholinesterase-active sites and turnover in insects
Chentanez_2000_J.Med.Assoc.Thai_83_1196 New classification of histochemical staining patterns of acetylcholinesterase activity in rectal suction biopsy in Hirschsprung's disease
Chentanez_2000_J.Med.Assoc.Thai_83_1101 Modification of the acetylcholinesterase (AchE) staining method in Hirschsprung's disease
Chu_2000_Brain.Res_887_399 Nicotinic acetylcholine receptor-mediated synaptic potentials in rat neocortex
Chuiko_2000_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_127_233 Comparative study of acetylcholinesterase and butyrylcholinesterase in brain and serum of several freshwater fish: specific activities and in vitro inhibition by DDVP, an organophosphorus pesticide
Cook_2000_Aliment.Pharmacol.Ther_14_1287 Abnormal contractile properties of rectal smooth muscle in chronic ulcerative colitis
Cuevas_2000_Chemistry_6_3228 Toward an artifical acetylcholinesterase
Cummings_2000_Lancet_356_2024 Cholinesterase inhibitors: expanding applications
Dawson_2000_Rheumatology.(Oxford)_39_1226 An investigation of interactions between the immune system and stimulus-secretion coupling in mouse submandibular acinar cells. A possible mechanism to account for reduced salivary flow rates associated with the onset of Sjogren's syndrome
de Castro_2000_Toxicol.Lett_118_93 Relevance of developmental testing of exposure to methamidophos during gestation to its toxicology evaluation
Deleu_2000_Arch.Neurol_57_1380 Donepezil in the treatment of Alzheimer disease
Diez_2000_Neurosci_100_259 Neuropeptides in hippocampus and cortex in transgenic mice overexpressing V717F beta-amyloid precursor protein--initial observations
Domeneghini_2000_Eur.J.Histochem_44_295 Neurotransmitters and putative neuromodulators in the gut of Anguilla anguilla (L.). Localizations in the enteric nervous and endocrine systems
Doorn_2000_Chem.Res.Toxicol_13_1313 Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group
Doss-Pepe_2000_Biochemistry_39_14884 Interaction of collagen-like peptide models of asymmetric acetylcholinesterase with glycosaminoglycans: spectroscopic studies of conformational changes and stability
Drake_2000_Lab.Invest_80_1491 Structural and functional denervation of human detrusor after spinal cord injury
Dringenberg_2000_Neuroreport_11_3513 Increased effectiveness of tacrine by deprenyl co-treatment in rats: EEG and behavioral evidence
Dronfield_2000_J.Psychopharmacol_14_275 Comparison of donepezil-, tacrine-, rivastigmine- and metrifonate-induced central and peripheral cholinergically mediated responses in the rat
Dube_2000_Indian.J.Physiol.Pharmacol_44_50 Antidotal efficacy of pyridinium oximes and cholineacetyltransferase inhibitors against organophosphorus intoxication in rodents
Ellies_2000_J.Oral.Maxillofac.Surg_58_1251 The effect of local injection of botulinum toxin A on the parotid gland of the rat: an immunohistochemical and morphometric study
Farag_2000_Reprod.Toxicol_14_457 Reproductive toxicology of acephate in male mice
Farlow_2000_Eur.Neurol_44_236 A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease
Fellowes_2000_Parasitol_121 ( Pt 3)_325 Classical neurotransmitters in the ovijector of Ascaris suum: localization and modulation of muscle activity
Fillit_2000_Am.J.Manag.Care_6_S1149 Managed care decisions in Alzheimer's disease
Fillit_2000_Am.J.Manag.Care_6_S1139 The pharmacoeconomics of Alzheimer's disease
Fisher_2000_Jpn.J.Pharmacol_84_101 Therapeutic strategies in Alzheimer's disease: M1 muscarinic agonists
Flora_2000_Cytobios_103_103 Alterations in some membrane properties in rat brain following exposure to lead
Freeman_2000_Proc.Natl.Acad.Sci.U.S.A_97_13877 Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology
Furey_2000_Science_290_2315 Cholinergic enhancement and increased selectivity of perceptual processing during working memory
Gao_2000_J.Agric.Food.Chem_48_4717 Comparative toxicity of selected organophosphate insecticides against resistant and susceptible clones of the greenbug, Schizaphis graminum (Homoptera: aphididae)
Giacobini_2000_Neurochem.Res_25_1185 Cholinesterase inhibitors stabilize Alzheimer disease
Gimenez-Pardo_2000_Parasite_7_237 Detection of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in Dicrocoelium dendriticum
Goel_2000_Biol.Trace.Elem.Res_74_171 Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study
Grace_2000_Int.J.Geriatr.Psychiatry_15_1028 A comparison of sleep profiles in patients with dementia with lewy bodies and Alzheimer's disease
Gruttadauria_2000_G.Chir_21_353 Correlation between cytochrome P-450 system and liver function tests during experimental liver transplantation
Guidry_2000_Auton.Neurosci_82_97 Absence of cholinergic sympathetic innervation from limb muscle vasculature in rats and mice
Guven_2000_Am.J.Emerg.Med_18_640 Intravenous organophosphate intoxication
Harold_2000_Arch.Insect.Biochem.Physiol_45_47 Characterization of esterases associated with profenofos resistance in the tobacco budworm, Heliothis virescens (F.)
Heller_2000_Acta.Anaesthesiol.Scand_44_1024 Epidural abscess after epidural catheter for pain release during pancreatitis
Herrman_2000_Food.Addit.Contam_17_551 Acute intake assessment: evolution within the Codex Committee on Pesticide Residues. WHO Joint Secretary of the Joint FAO\/WHO meeting on pesticide residues JMPR
Horvath_2000_Eur.J.Pharmacol_405_33 Postnatal treatment with ACTH-(4-9) analog ORG 2766 attenuates N-methyl-D-aspartate-induced excitotoxicity in rat nucleus basalis in adulthood
Hou_2000_Am.J.Chin.Med_28_379 Honokiol and magnolol increased hippocampal acetylcholine release in freely-moving rats
Iliev_2000_J.Pharm.Pharmacol_52_1151 A post-ischaemic single administration of galanthamine, a cholinesterase inhibitor, improves learning ability in rats
Jaganathan_2000_Bioorg.Chem_28_242 Distinct Effect of Benzalkonium Chloride on the Esterase and Aryl Acylamidase Activities of Butyrylcholinesterase
Jain_2000_Expert.Opin.Investig.Drugs_9_1397 Evaluation of memantine for neuroprotection in dementia
Jann_2000_J.Am.Pharm.Assoc.(Wash)_40_S50 Supportive care for the patient with Alzheimer's disease
Jeyarasasingam_2000_J.Pharmacol.Exp.Ther_295_314 Nitric oxide is involved in acetylcholinesterase inhibitor-induced myopathy in rats
Johnson_2000_Int.J.Dev.Neurosci_18_781 Cholinesterases modulate cell adhesion in human neuroblastoma cells in vitro
Kaneko_2000_Hepatogastroenterology_47_1636 A new method of functional scintiphotosplenoportography using technetium-99m-DTPA-galactosylated human serum albumin
Karch_2000_Am.J.Emerg.Med_18_635 Interpretation of blood cocaine and metabolite concentrations
Karunaratne_2000_Med.Vet.Entomol_14_430 Insecticide resistance spectra and resistance mechanisms in populations of Japanese encephalitis vector mosquitoes, Culex tritaeniorhynchus and Cx. gelidus, in Sri Lanka
Katsoudas_2000_J.Food.Prot_63_1758 Enzyme inhibition and enzyme-linked immunosorbent assay methods for carbamate pesticide residue analysis in fresh produce
Khrunin_2000_Gig.Sanit__66 [Anticholinesterase effect of potential organophosphorus synergists of pyrethroids]
Kim_2000_Environ.Res_84_303 A convenient method for oxidation of organophosphorus pesticides in organic solvents
Korczyn_2000_Expert.Opin.Investig.Drugs_9_2259 Muscarinic M(1) agonists in the treatment of Alzheimer's disease
Kunzle_2000_Anat.Embryol.(Berl)_202_507 Multiarchitectonic characterization of insular, perirhinal and related regions in a basal mammal, Echinops telfairi
Kunzle_2000_Anat.Embryol.(Berl)_202_491 The subrhinal paleocortex in the hedgehog tenrec: a multiarchitectonic characterization and an analysis of its connections with the olfactory bulb
Kwong_2000_Histochem.J_32_521 Neurotransmitters, neuropeptides and calcium binding proteins in developing human cerebellum: a review
Lall_2000_Indian.J.Pediatr_67_583 Neonatal Hirschsprung's disease
Lam_2000_Pharmacol.Toxicol_87_11 Four weeks' inhalation exposure of Long Evans rats to 4-tert-butyltoluene: effect on evoked potentials, behaviour, and brain neurochemistry
Lim_2000_Eur.J.Pharmacol_404_353 Acetylcholinesterase-independent action of diisopropyl-flurophosphate in the rat aorta
Lund_2000_Aquat.Toxicol_48_127 The sensitivity of grass shrimp, Palaemonetes pugio, embryos to organophosphate pesticide induced acetylcholinesterase inhibition
Lutz_2000_Int.J.Occup.Med.Environ.Health_13_215 Long-term effects of acute exposure to chlorphenvinphos on behavioural responsiveness to amphetamine and scopolamine in rats
Martinez_2000_Eur.J.Med.Chem_35_913 N-Benzylpiperidine derivatives of 1,2,4-thiadiazolidinone as new acetylcholinesterase inhibitors
Martinez-Ciriano_2000_Histol.Histopathol_15_1093 Intrinsic innervation in the intestine of the lizard Podarcis hispanica
Martos_2000_An.Esp.Pediatr_53_330 [High levels of alanine aminotransferase and cholinesterase in obese pre-pubertal children: correlation with basal insulin concentration and anthropometric measures]
Marx_2000_Thromb.Haemost_83_297 Characterization of mouse thrombin-activatable fibrinolysis inhibitor
Mattila_2000_J.Med.Genet_37_766 Dipeptidyl carboxypeptidase 1 (DCP1) and butyrylcholinesterase (BCHE) gene interactions with the apolipoprotein E epsilon4 allele as risk factors in Alzheimer's disease and in Parkinson's disease with coexisting Alzheimer pathology
McKeith_2000_Lancet_356_2031 Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study
Melter_2000_Am.J.Gastroenterol_95_3522 Progressive familial intrahepatic cholestasis: partial biliary diversion normalizes serum lipids and improves growth in noncirrhotic patients
Monserrat_2000_Environ.Toxicol.Pharmacol_9_39 Methodological and biological aspects to be considered in acetylcholinesterase reactivation assays using 2-PAM
Moralev_2000_Dokl.Biochem_373_156 Variability of the structure of the cholinesterase active center as studied by factor analysis
Moser_2000_Neurotoxicol.Teratol_22_713 Dose-response and time-course of neurobehavioral changes following oral chlorpyrifos in rats of different ages
Mu_2000_Anat.Rec_260_308 Neuromuscular specializations of the pharyngeal dilator muscles: II. Compartmentalization of the canine genioglossus muscle
Okumura_2000_Brain.Dev_22 Suppl 1_S27 The cat neostriatum: relative distribution of cholinergic neurons versus serotonergic fibers
Piasecka_2000_Scand.J.Clin.Lab.Invest_60_395 Effect of combined treatment with perindoprilat and low-power red light laser irradiation on human erythrocyte membrane fluidity, membrane potential and acetylcholinesterase activity
Pilon_2000_Mol.Biol.Cell_11_3277 The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion
Pitts_2000_Br.J.Anaesth_85_592 Determination of succinylcholine in plasma by high-pressure liquid chromatography with electrochemical detection
Plataras_2000_Clin.Biochem_33_351 Effect of CDP-choline on brain acetylcholinesterase and Na(+), K(+)-ATPase in adult rats
Pregelj_2000_Pflugers.Arch_440_R112 Effect of mechanical load on acetylcholinesterase mRNA levels in the slow soleus muscle of the rat
Rahman_2000_Ecotoxicol.Environ.Saf_47_125 Inhibition of acetylcholinesterase and different ATPases by a novel phosphorothionate (RPR-II) in rat brain
Rajasekaran_2000_Environ.Toxicol.Pharmacol_9_25 Effects of combined exposure to aluminium and ethanol on food intake, motor behaviour and a few biochemical parameters in pubertal rats
Reichman_2000_Am.J.Manag.Care_6_S1125 Alzheimer's disease: clinical treatment options
Ringman_2000_Neurology_55_870 Treatment of REM sleep behavior disorder with donepezil: a report of three cases
Robertson_2000_J.Comp.Neurol_426_632 Do subplate neurons comprise a transient population of cells in developing neocortex of rats?
Rohrbaugh_2000_J.Chromatogr.A_893_393 Methanol chemical ionization quadrupole ion trap mass spectrometry of O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothiolate (VX) and its degradation products
Rozengart_2000_Dokl.Biochem_374_192 Hemolymph cholinesterase of the Pacific gastropod Neptunea eulimata: substrate-inhibitor analysis
Saez-Valero_2000_J.Neurol.Neurosurg.Psychiatry_69_664 Altered glycosylation of acetylcholinesterase in lumbar cerebrospinal fluid of patients with Alzheimer's disease
Sams_2000_Toxicol.Lett_116_217 Evidence for the activation of organophosphate pesticides by cytochromes P450 3A4 and 2D6 in human liver microsomes
Samuel_2000_Int.J.Geriatr.Psychiatry_15_794 Better cognitive and psychopathologic response to donepezil in patients prospectively diagnosed as dementia with Lewy bodies: a preliminary study
Sato_2000_J.Immunol_165_1053 Pro-carboxypeptidase R is an acute phase protein in the mouse, whereas carboxypeptidase N is not
Schachter_2000_Curr.Treat.Options.Neurol_2_51 Alzheimer's Disease
Schafer_2000_Anesthesiology_92_1207 Analgesic effects of neostigmine in the periphery
Scott_2000_Drugs_60_1095 Galantamine: a review of its use in Alzheimer's disease
Segal_2000_J.Morphol_246_103 Motor nerve topology reflects myocyte morphology in hamster retractor and epitrochlearis muscles
Shigenobu_2000_Nature_407_81 Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS
Stahl_2000_J.Clin.Psychiatry_61_710 The new cholinesterase inhibitors for Alzheimer's disease, Part 1: their similarities are different
Stahl_2000_J.Clin.Psychiatry_61_813 The new cholinesterase inhibitors for Alzheimer's disease, Part 2: illustrating their mechanisms of action
Stone_2000_Brain.Res_882_9 Protractive effects of chronic treatment with an acutely sub-toxic regimen of diisopropylflurophosphate on the expression of cholinergic receptor densities in rats
Storm_2000_Toxicology_150_1 Occupational exposure limits for 30 organophosphate pesticides based on inhibition of red blood cell acetylcholinesterase
Sulaiman_2000_J.Pathol_192_396 Growth of nerve fibres into murine peritoneal adhesions
Sunanda_2000_Neurochem.Res_25_1547 Restraint stress-induced alterations in the levels of biogenic amines, amino acids, and AChE activity in the hippocampus
Taghvaei_2000_J.Biotechnol_81_107 Adsorptive immobilization of erythrocyte membrane
Thal_2000_Neurology_55_805 A 1-year controlled trial of acetyl-l-carnitine in early-onset AD
Torrao_2000_Brain.Res.Dev.Brain.Res_124_81 Expression of cholinergic system molecules during development of the chick nervous system
Tsakiris_2000_Z.Naturforsch.C_55_852 The effect of galactose metabolic disorders on rat brain acetylcholinesterase activity
Turchi_2000_Eur.J.Neurosci_12_4505 Cortical cholinergic inputs mediate processing capacity: effects of 192 IgG-saporin-induced lesions on olfactory span performance
Viragh_2000_Biochemistry_39_16200 NMR evidence for a short, strong hydrogen bond at the active site of a cholinesterase
Wang_2000_Environ.Health.Perspect_108_1103 An unusual case of organophosphate intoxication of a worker in a plastic bottle recycling plant: an important reminder
Weinbroum_2000_Resuscitation_47_113 Anaesthesia and critical care considerations in nerve agent warfare trauma casualties
Wester_2000_Toxicol.Appl.Pharmacol_168_149 Predicted chemical warfare agent VX toxicity to uniformed soldier using parathion in vitro human skin exposure and absorption
Whelan_2000_Ann.Clin.Psychiatry_12_131 Donepezil in the treatment of cognitive dysfunction associated with traumatic brain injury
Wilens_2000_J.Child.Adolesc.Psychopharmacol_10_217 Adjunctive donepezil in attention deficit hyperactivity disorder youth: case series
Wrobel_2000_Anat.Embryol.(Berl)_202_475 Morphogenesis of the bovine rete testis: the intratesticular rete and its connection to the seminiferous tubules
Wu_2000_Exp.Neurol_165_306 Cyto- and chemoarchitecture of basal forebrain cholinergic neurons in the common marmoset (Callithrix jacchus)
Yang_2000_Exp.Neurol_166_166 Open-loop and closed-loop optokinetic nystagmus (OKN) in myasthenia gravis and nonmyasthenic subjects
Yorston_2000_J.Psychopharmacol_14_303 Hypnopompic hallucinations with donepezil
Young_2000_J.Morphol_245_130 Examination of intrafascicular muscle fiber terminations: implications for tension delivery in series-fibered muscles
Zavodnik_2000_Biochemistry.(Mosc)_65_946 Hypochlorous acid-induced lysis of human erythrocytes. Inhibition of cellular damage by the isoflavonoid genistein-8-C-glucoside
Zhang_2000_Neurosci.Lett_292_41 Huperzine B, a novel acetylcholinesterase inhibitor, attenuates hydrogen peroxide induced injury in PC12 cells
Zhang_2000_Neurosci.Lett_295_116 Similar potency of the enantiomers of huperzine A in inhibition of [(3)H]dizocilpine (MK-801) binding in rat cerebral cortex
Zhu_2000_Exp.Neurol_166_136 Postinjury administration of L-deprenyl improves cognitive function and enhances neuroplasticity after traumatic brain injury
Zwart_2000_J.Neurochem_75_2492 Competitive potentiation of acetylcholine effects on neuronal nicotinic receptors by acetylcholinesterase-inhibiting drugs
Szeltner_2000_J.Biol.Chem_275_15000 The noncatalytic beta-propeller domain of prolyl oligopeptidase enhances the catalytic capability of the peptidase domain
Arca_2000_Clin.Genet_58_369 The common mutations in the lipoprotein lipase gene in Italy: effects on plasma lipids and angiographically assessed coronary atherosclerosis
Berggren_2000_J.Chromatogr.B.Biomed.Sci.Appl_743_295 Partitioning of peptides and recombinant protein-peptide fusions in thermoseparating aqueous two-phase systems: effect of peptide primary structure
Boney_2000_Mol.Endocrinol_14_805 The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes
Brown_2000_Enzyme.Microb.Technol_26_801 Accelerated prediction of recombinant protein production in Saccharomyces cerevisiae by using rapid monitoring techniques
Carroll_2000_Tuber.Lung.Dis_80_117 Identification of Mycobacterium avium DNA sequences that encode exported proteins by using phoA gene fusions
Christov_2000_J.Biotechnol_83_231 Effects of purified endo-beta-1,4-xylanases of family 10 and 11 and acetyl xylan esterases on eucalypt sulfite dissolving pulp
Clee_2000_J.Lipid.Res_41_521 Plasma and vessel wall lipoprotein lipase have different roles in atherosclerosis
Couture_2000_Arterioscler.Thromb.Vasc.Biol_20_815 Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles: The Framingham Offspring Study
Deeb_2000_J.Lipid.Res_41_155 The C-514T polymorphism in the human hepatic lipase gene promoter diminishes its activity
Despres_2000_Arterioscler.Thromb.Vasc.Biol_20_1932 Race, visceral adipose tissue, plasma lipids, and lipoprotein lipase activity in men and women: the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) family study
Dessen_2000_Biochim.Biophys.Acta_1488_40 Structure and mechanism of human cytosolic phospholipase A(2)
Ferreira_2000_Bioseparation_9_1 Anion exchange purification of plasmid DNA using expanded bed adsorption
Garenc_2000_Metabolism_49_432 Linkage and association studies of the lipoprotein lipase gene with postheparin plasma lipase activities, body fat, and plasma lipid and lipoprotein concentrations: the HERITAGE Family Study
Hall_2000_Genet.Epidemiol_18_203 Frequency and allelic association of common variants in the lipoprotein lipase gene in different ethnic groups: the Wandsworth Heart and Stroke Study
Ho_2000_Yeast_17_272 Comparison of Mycobacterium tuberculosis genomes reveals frequent deletions in a 20 kb variable region in clinical isolates
Hoffer_2000_Atherosclerosis_151_443 The V73M mutation in the hepatic lipase gene is associated with elevated cholesterol levels in four Dutch pedigrees with familial combined hyperlipidemia
Holmer_2000_Cardiovasc.Res_47_806 Lipoprotein lipase gene polymorphism, cholesterol subfractions and myocardial infarction in large samples of the general population
Leibowitz_2000_FEBS.Lett_473_333 Activation of PPARdelta alters lipid metabolism in db\/db mice
Masaki_2000_Am.J.Physiol.Regul.Integr.Comp.Physiol_279_R1305 Impaired response of UCP family to cold exposure in diabetic (db\/db) mice
Moennig_2000_Atherosclerosis_149_395 Detection of missense mutations in the genes for lipoprotein lipase and hepatic triglyceride lipase in patients with dyslipidemia undergoing coronary angiography
Nicklas_2000_Hum.Genet_106_420 Lipoprotein lipase gene variation is associated with adipose tissue lipoprotein lipase activity, and lipoprotein lipid and glucose concentrations in overweight postmenopausal women
Proenza_2000_Int.J.Obes.Relat.Metab.Disord_24_93 Association of sets of alleles of genes encoding beta3-adrenoreceptor, uncoupling protein 1 and lipoprotein lipase with increased risk of metabolic complications in obesity
Razzaghi_2000_Hum.Genet_107_257 Genetic screening of the lipoprotein lipase gene for mutations associated with high triglyceride\/low HDL-cholesterol levels
Rees_2000_Enzyme.Microb.Technol_27_549 Chemical modification probes accessibility to organic phase: proteins on surfaces are more exposed than in lyophilized powders
Reue_2000_J.Lipid.Res_41_1067 Adipose tissue deficiency, glucose intolerance, and increased atherosclerosis result from mutation in the mouse fatty liver dystrophy (fld) gene
Sass_2000_J.Hypertens_18_1775 Lipoprotein lipase (C\/G)447 polymorphism and blood pressure in the Stanislas Cohort
Schultz_2000_J.Lipid.Res_41_214 Adrenal and liver in normal and cld\/cld mice synthesize and secrete hepatic lipase, but the lipase is inactive in cld\/cld mice
Senti_2000_Atherosclerosis_150_135 Relationship of abdominal adiposity and dyslipemic status in women with a common mutation in the lipoprotein lipase gene. The REGICOR investigators
Seo_2000_J.Biol.Chem_275_30355 Lipoprotein lipase-mediated selective uptake from low density lipoprotein requires cell surface proteoglycans and is independent of scavenger receptor class B type 1
Amouyal-Barkate_2000_Ann.Pharmacother_34_1347 Abnormal movements with donepezil in Alzheimer disease
Babic_2000_Age.Ageing_29_370 Spontaneous rupture of oesophagus (Boerhaave's syndrome) related to rivastigmine
Beare_2000_Med.J.Aust_172_96 Organophosphate poisoning versus brainstem stroke
Biely_2000_Biochim.Biophys.Acta_1474_360 Inverting character of alpha-glucuronidase A from Aspergillus tubingensis
Brandt_2000_Adv.Exp.Med.Biol_477_97 Development of a tertiary-structure model of the C-terminal domain of DPP IV
de la Torre_2000_Environ.Pollut_109_277 Biomarkers assessment in juvenile Cyprinus carpio exposed to waterborne cadmium
De Vos_2000_Nucl.Med.Biol_27_745 Pharmacological evaluation of [11C]donepezil as a tracer for visualization of acetylcholinesterase by PET
de Vries_2000_Carbohydr.Res_327_401 Synergy between enzymes from Aspergillus involved in the degradation of plant cell wall polysaccharides
DeLucchi_2000_Int.Tinnitus.J_6_37 Transtympanic pilocarpine in tinnitus
Durinx_2000_Eur.J.Biochem_267_5608 Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26\/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides
Fergusson_2000_Int.J.Geriatr.Psychiatry_15_280 Donepezil for the treatment of psychosis in dementia with Lewy bodies
Fotiou_2000_Int.J.Psychophysiol_37_111 Changes in pupil reaction to light in Alzheimer's disease patients: a preliminary report
Fretland_2000_Chem.Biol.Interact_129_41 Epoxide hydrolases: biochemistry and molecular biology
Greene_2000_Chem.Res.Toxicol_13_217 Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase
Greene_2000_Arch.Biochem.Biophys_376_420 Metabolism of monoepoxides of methyl linoleate: bioactivation and detoxification
Greene_2000_J.Clin.Psychopharmacol_20_350 A 12-week, open trial of donepezil hydrochloride in patients with multiple sclerosis and associated cognitive impairments
Gupta_2000_Prim.Care.Companion.J.Clin.Psychiatry_2_227 Acetylcholinesterase Inhibitors: Treatment of Dementia-Related Behavioral Disturbances
Hashimoto_2000_Lancet_356_568 Urinary incontinence: an unrecognised adverse effect with donepezil
Homma_2000_Dement.Geriatr.Cogn.Disord_11_299 Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan. E2020 Study Group
Huang_2000_Neurosci.Lett_284_116 Cloning, heterologous expression and co-assembly of Mpbeta1, a nicotinic acetylcholine receptor subunit from the aphid Myzus persicae
Kasa_2000_Neurosci_101_89 Donepezil dose-dependently inhibits acetylcholinesterase activity in various areas and in the presynaptic cholinergic and the postsynaptic cholinoceptive enzyme-positive structures in the human and rat brain
Koppenhofer_2000_J.Econ.Entomol_93_71 Biological control agents for white grubs (Coleoptera: Scarabaeidae) in anticipation of the establishment of the Japanese beetle in California
Kumar_2000_Eur.J.Neurol_7_159 An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors
Lee_2000_Nucl.Med.Biol_27_741 Synthesis and biological evaluation of 1-(4-[18F]fluorobenzyl)-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine for in vivo studies of acetylcholinesterase
Lermontova_2000_Bull.Exp.Biol.Med_129_544 Dimebon improves learning in animals with experimental Alzheimer's disease
Marighetto_2000_Learn.Mem_7_159 Further evidence for a dissociation between different forms of mnemonic expressions in a mouse model of age-related cognitive decline: effects of tacrine and S 17092, a novel prolyl endopeptidase inhibitor
Pan_2000_Acta.Pharmacol.Sin_21_124 Learning deficits induced by 4 belladonna alkaloids are preferentially attenuated by tacrine
Perez-Mendoza_2000_J.Econ.Entomol_93_31 Alterations in esterases are associated with malathion resistance in Habrobracon hebetor (Hymenoptera: Braconidae)
Pruett_2000_J.Econ.Entomol_93_920 Evaluation of horn flies (Diptera: Muscidae) from a pyrethroid susceptible colony for general and permethrin esterase activities
Querfurth_2000_Dement.Geriatr.Cogn.Disord_11_314 Acetylcholinesterase inhibition in dementia with Lewy bodies: results of a prospective pilot trial
Smyth_2000_Heredity.(Edinb)_84 ( Pt 1)_63 MCE activities and malathion resistances in field populations of the australian sheep blowfly (Lucilia cuprina)
Stockel-Maschek_2000_Adv.Exp.Med.Biol_477_117 Potent inhibitors of dipeptidyl peptidase IV and their mechanisms of inhibition
Terao_2000_Lancet_355_2168 Charles Bonnet syndrome and dementia
Tullu_2000_Indian.Pediatr_37_88 Dorfman-Chanarin syndrome: a rare neutral lipid storage disease
Vais_2000_FEBS.Lett_470_135 A single amino acid change makes a rat neuronal sodium channel highly sensitive to pyrethroid insecticides
Vais_2000_J.Gen.Physiol_115_305 Activation of Drosophila sodium channels promotes modification by deltamethrin. Reductions in affinity caused by knock-down resistance mutations
Verrico_2000_J.Am.Geriatr.Soc_48_1659 Fulminant chemical hepatitis possibly associated with donepezil and sertraline therapy
Wollenberg_2000_Acta.Derm.Venereol_80_39 Dorfman-Chanarin syndrome in a Turkish kindred: conductor diagnosis requires analysis of multiple eosinophils
Yamada_2000_J.Biol.Chem_275_23082 Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolase
Zhu_2000_Pestic.Biochem.Physiol_67_155 Elevated Esterases Exhibiting Arylesterase-like Characteristics in an Organophosphate-Resistant Clone of the Greenbug, Schizaphis graminum (Homoptera: Aphididae)
Rey_2000_Pestic.Biochem.Physiol_67_103 Differential Sensitivity to Vegetable Tannins in Planktonic Crustacea from Alpine Mosquito Breeding Sites
Ottea_2000_Pestic.Biochem.Physiol_66_20 Mechanisms of Pyrethroid Resistance in Larvae and Adults from a Cypermethrin-Selected Strain of Heliothis virescens (F.)
Van Dyke_2000_Ann.Pharmacother_34_639 Pharmacogenetic screening for susceptibility to fetal malformations in women
Wenker_2000_Toxicol.Appl.Pharmacol_169_52 Metabolism of styrene-7,8-oxide in human liver in vitro: interindividual variation and stereochemistry
Wild_2000_Int.J.Cancer_86_1 Environmental and genetic determinants of aflatoxin-albumin adducts in the Gambia
Willett_2000_Toxicol.Sci_58_68 Comparative metabolism and excretion of benzo(a)pyrene in 2 species of ictalurid catfish
Williams_2000_Cancer.Res_60_4667 Mammary expression of xenobiotic metabolizing enzymes and their potential role in breast cancer
Wilson_2000_Faseb.J_14_791 Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction
Wong_2000_Toxicol.Lett_115_17 Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population
Yim_2000_Thorax_55_121 Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1
Yoshikawa_2000_Int.J.Mol.Med_5_49 Microsomal epoxide hydrolase genotypes and chronic obstructive pulmonary disease in Japanese
Zaitsu_2000_Blood_96_601 New induction of leukotriene A(4) hydrolase by interleukin-4 and interleukin-13 in human polymorphonuclear leukocytes
Zocher_2000_J.Biotechnol_77_287 Epoxide hydrolase activity of Streptomyces strains
Heinonen_2000_Molec.Genet.Metab_69_123 Expression of palmitoyl protein thioesterase in neurons.
Heinonen_2000_Mol.Genet.Metab_69_123 Expression of palmitoyl protein thioesterase in neurons
Villatte_2000_Pestic.Biochem.Physiol_67_95 A High Number of Mutations in Insect Acetylcholinesterase May Provide Insecticide Resistance
Bainy_2000_Aquaculture_191_163 Biochemical responses in penaeids caused by contaminants
Aitcheson_2000_Aquaculture_183_269 Removal of aquaculture therapeutants by carbon adsorption: 1. Equilibrium adsorption behaviour of single components
Abgrall_2000_Aquaculture_181_1 Sublethal effects of azamethiphos on shelter use by juvenile lobsters (Homarus americanus)
Byrne_2000_Pest.Manag.Sci_56_867 The role of B-type esterases in conferring insecticide resistance in the tobacco whitefly, Bemisia tabaci (Genn)
Copping_2000_Pest.Manag.Sci_56_651 Biopesticides: a review of their action, applications and efficacy
Elbert_2000_Pest.Manag.Sci_56_60 Resistance of Bemisia tabaci (Homoptera: Aleyrodidae) to insecticides in southern Spain with special reference to neonicotinoids
Sales_2000_Pest.Manag.Sci_56_825 Avian whole-brain spheroid cultures: applications in pesticide toxicity
Scott_2000_Pest.Manag.Sci_56_147 Insecticide resistance in house flies from caged-layer poultry facilities
Singh_2000_Pest.Manag.Sci_56_889 Toxicity to the snail Limnaea acuminata of plant-derived molluscicides in combination with synergists
Villatte_2000_Pest.Manag.Sci_56_1023 Is acetyl\/butyrylcholine specificity a marker for insecticide-resistance mutations in insect acetylcholinesterase?
Zanella_2000_Pest.Manag.Sci_56_804 Determination of carbofuran in pesticide formulations by flow injection spectrophotometry
Nachmansohn_2000_Yale.J.Biol.Med_73_241 On the physiological significance of choline esterase. 1939
Miled_2000_Biochimie_82_973 Digestive lipases: from three-dimensional structure to physiology
Allman_2000_Mol.Pharmacol_58_175 Scanning mutagenesis identifies amino acid side chains in transmembrane domain 5 of the M(1) muscarinic receptor that participate in binding the acetyl methyl group of acetylcholine
Bren_2000_J.Biol.Chem_275_12692 Hydrophobic pairwise interactions stabilize alpha-conotoxin MI in the muscle acetylcholine receptor binding site
Caron_2000_Life.Sci_67_447 Effects of ethanol on phosphoinositide hydrolysis and muscarinic acetylcholine receptor number in SH-SY5Y cells
Erickson_2000_FASEB.J_14_2450 Molecular analysis of vesicular amine transporter function and targeting to secretory organelles
Farber_2000_FASEB.J_14_2198 Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease
Felder_2000_J.Med.Chem_43_4333 Therapeutic opportunities for muscarinic receptors in the central nervous system
Grosman_2000_J.Gen.Physiol_116_327 The extracellular linker of muscle acetylcholine receptor channels is a gating control element
Lansdell_2000_Neuropharmacol_39_2604 Cloning and heterologous expression of Dalpha4, a Drosophila neuronal nicotinic acetylcholine receptor subunit: identification of an alternative exon influencing the efficiency of subunit assembly
Lansdell_2000_Neuropharmacol_39_671 The influence of nicotinic receptor subunit composition upon agonist, alpha-bungarotoxin and insecticide (imidacloprid) binding affinity
Lu_2000_J.Biol.Chem_275_5682 A network of conserved intramolecular contacts defines the off-state of the transmembrane switch mechanism in a seven-transmembrane receptor
Malany_2000_Biochemistry_39_15388 Orientation of alpha-neurotoxin at the subunit interfaces of the nicotinic acetylcholine receptor
Osaka_2000_J.Biol.Chem_275_5478 Pairwise electrostatic interactions between alpha-neurotoxins and gamma, delta, and epsilon subunits of the nicotinic acetylcholine receptor
Paas_2000_Trends.Pharmacol.Sci_21_87 How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors
Quiram_2000_J.Biol.Chem_275_4889 Pairwise interactions between neuronal alpha(7) acetylcholine receptors and alpha-conotoxin PnIB
Rosenblum_2000_J.Neurosci_20_977 ERKI\/II regulation by the muscarinic acetylcholine receptors in neurons
Schiavo_2000_Physiol.Rev_80_717 Neurotoxins affecting neuroexocytosis
Slack_2000_Biochem.J_348 Pt 2_381 The m3 muscarinic acetylcholine receptor is coupled to mitogen-activated protein kinase via protein kinase C and epidermal growth factor receptor kinase
Taylor_2000_Pflugers.Arch_440_R115 Subunit interface selective toxins as probes of nicotinic acetylcholine receptor structure
Testai_2000_Neurochem.Int_36_27 Histidine 186 of the nicotinic acetylcholine receptor alpha subunit requires the presence of the 192-193 disulfide bridge to interact with alpha-bungarotoxin
Wang_2000_J.Gen.Physiol_116_449 Fundamental gating mechanism of nicotinic receptor channel revealed by mutation causing a congenital myasthenic syndrome
Cohen_2000_Infect.Immun_68_4549 Attenuated nontoxinogenic and nonencapsulated recombinant Bacillus anthracis spore vaccines protect against anthrax
D'Agostino_2000_Eur.J.Pharmacol_396_29 Tachykinin NK(2) receptors facilitate acetylcholine release from guinea-pig isolated trachea
Domino_2000_Eur.J.Pharmacol_393_315 Round table on nicotinic receptors in addiction: summary report
Godfraind_2000_J.Cereb.Blood.Flow.Metab_20_145 Hypoxia on hippocampal slices from mice deficient in dystrophin (mdx) and isoforms (mdx3cv)
Krnjevic_2000_J.Neurophysiol_83_879 2-Deoxyglucose-induced long-term potentiation of monosynaptic IPSPs in CA1 hippocampal neurons
Mang_2000_Br.J.Pharmacol_131_94 Modulation of acetylcholine release in the guinea-pig trachea by the nitric oxide donor, S-nitroso-N-acetyl-DL-penicillamine (SNAP)
Miranda_2000_Prog.Neurobiol_62_633 The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease
Zhang_2000_Brain.Res_876_103 2-deoxyglucose induces LTP in layer I of rat somatosensory cortex in vitro
Zhao_2000_J.Neurophysiol_83_177 2-Deoxyglucose-induced long-term potentiation in CA1 is not prevented by intraneuronal chelator
Dunn_2000_Biochem.Biophys.Res.Commun_279_358 Roles of agonist-binding sites in nicotinic acetylcholine receptor function
Gallopin_2000_Nature_404_992 Identification of sleep-promoting neurons in vitro
Kawai_2000_Biochemistry_39_3867 Interaction of a semirigid agonist with Torpedo acetylcholine receptor
Khakh_2000_Nature_406_405 State-dependent cross-inhibition between transmitter-gated cation channels
Kovoor_2000_J.Biol.Chem_275_3397 Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins
Rickman_2000_Mayo.Clin.Proc_75_1321 Fulminant autoimmune cortical encephalitis associated with thymoma treated with plasma exchange
Vernino_2000_N.Engl.J.Med_343_847 Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies
Scali_2000_Eur.J.Neurosci_12_1900 Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease
Gomez_2000_Brain.Res.Bull_52_263 The effect of isoflurane on the release of [(3)H]-acetylcholine from rat brain cortical slices
Santos_2000_J.Neurochem_74_2425 Visualization and trafficking of the vesicular acetylcholine transporter in living cholinergic cells
Jenkins_2000_Sci.Total.Environ_250_73 Phosphine generation by mixed- and monoseptic-cultures of anaerobic bacteria
Pouille_2000_J.Physiol_527 Pt 2_265 Dendro-somatic distribution of calcium-mediated electrogenesis in purkinje cells from rat cerebellar slice cultures
Volsen_2000_Methods.Enzymol_314_290 Application of antisense techniques to characterize neuronal ion channels in vitro
Zaninetti_2000_Neurosci_95_319 Magnocellular neurons of the rat supraoptic nucleus are endowed with functional nicotinic acetylcholine receptors
Zaninetti_2000_Neurosci_100_589 Nicotinic acetylcholine receptors in neonatal motoneurons are regulated by axotomy: an electrophysiological and immunohistochemical study in human bcl-2 transgenic mice
Franceschini_2000_Behav.Brain.Res_113_3 Altered baroreflex responses in alpha7 deficient mice
Schutz_2000_Neurosci_96_707 Somatomotor neuron-specific expression of the human cholinergic gene locus in transgenic mice
Waterman_2000_Arthritis.Rheum_43_1647 Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjogren's syndrome
Weihe_2000_FASEB.J_14_2435 Chemical neuroanatomy of the vesicular amine transporters
Wilson_2000_J.Gen.Physiol_115_93 The intrinsic electrostatic potential and the intermediate ring of charge in the acetylcholine receptor channel
Akaaboune_2000_Mol.Cell.Neurosci_15_355 Developmental regulation of amyloid precursor protein at the neuromuscular junction in mouse skeletal muscle
Dai_2000_J.Cell.Biol_150_1321 The actin-driven movement and formation of acetylcholine receptor clusters
Kaksonen_2000_J.Cell.Sci_113 Pt 24_4421 Association of cortactin with dynamic actin in lamellipodia and on endosomal vesicles
Nunes-Tavares_2000_An.Acad.Bras.Cienc_72_331 Choline acetyltransferase detection in normal and denervated electrocyte from Electrophorus electricus (L.) using a confocal scanning optical microscopy analysis
Blake_2000_Trends.Neurosci_23_92 The neurobiology of duchenne muscular dystrophy: learning lessons from muscle?
Busetto_2000_J.Neurosci_20_685 Hebbian mechanisms revealed by electrical stimulation at developing rat neuromuscular junctions
Franken_2000_Naunyn.Schmiedebergs.Arch.Pharmacol_361_107 Testing the specificity of allosteric modulators of muscarinic receptors in phylogenetically closely related histamine H1-receptors
Hering_2000_J.Comp.Neurol_424_153 Distribution of the integrin beta 1 subunit on radial cells in the embryonic and adult avian retina
Jones_2000_Eur.J.Pharmacol_391_105 Effects of scopolamine in comparison with apomorphine and phencyclidine on prepulse inhibition in rats
Liu_2000_Zhong.Yao.Cai_23_524 [Morphological and histological identification and essential oil GC-MS assay of Aralia decaisneana]
Antil-Delbeke_2000_J.Biol.Chem_275_29594 Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor
Clementi_2000_Eur.J.Pharmacol_393_3 Neuronal nicotinic receptors, important new players in brain function
Cordeiro_2000_Neurosci.Res_38_385 Ca(2+) regulation of the carrier-mediated gamma-aminobutyric acid release from isolated synaptic plasma membrane vesicles
Di Angelantonio_2000_Br.J.Pharmacol_129_1771 Antagonism of nicotinic receptors of rat chromaffin cells by N,N, N-trimethyl-1-(4-trans-stilbenoxy)-2-propylammonium iodide: a patch clamp and ligand binding study
Michalet_2000_J.Biol.Chem_275_25608 Relative spatial position of a snake neurotoxin and the reduced disulfide bond alpha (Cys192-Cys193) at the alpha gamma interface of the nicotinic acetylcholine receptor
Mourier_2000_Protein.Eng_13_217 Chemical engineering of a three-fingered toxin with anti-alpha7 neuronal acetylcholine receptor activity
Roth_2000_Eur.J.Pharmacol_393_105 Targeting alpha7-containing nicotinic receptors on neurons to distal locations
Servent_2000_Eur.J.Pharmacol_393_197 Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors
Vailati_2000_Eur.J.Pharmacol_393_23 beta3 subunit is present in different nicotinic receptor subtypes in chick retina
Kofalvi_2000_J.Pharmacol.Exp.Ther_295_453 Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation
Sorbi_2000_Clin.Neuropharmacol_23_114 Double-blind, crossover, placebo-controlled clinical trial with L-acetylcarnitine in patients with degenerative cerebellar ataxia
Tian_2000_Toxicol.Appl.Pharmacol_167_246 Upregulation of tyrosine hydroxylase and downregulation of choline acetyltransferase in lead-exposed PC12 cells: the role of PKC activation
Vizi_2000_Pharmacol.Rev_52_63 Role of high-affinity receptors and membrane transporters in nonsynaptic communication and drug action in the central nervous system
Zhou_2000_Brain.Res_866_268 Developmental stage-dependent protective effect of NGF against lead cholinotoxicity in the rat septum
Chou_2000_Brain.Res.Mol.Brain.Res_77_232 Wnt-1 inhibits nerve growth factor-induced differentiation of PC12 cells by preventing the induction of some but not all late-response genes
Zaccaria_2000_J.Neuropathol.Exp.Neurol_59_103 Selective reduction in the nicotinic acetylcholine receptor and dystroglycan at the postsynaptic apparatus of mdx mouse superior cervical ganglion
Kenny_2000_J.Neurochem_75_2409 Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release
Abdalla_2000_Mol.Cell.Endocrinol_160_17 Effect of estrogen on intracellular signaling pathways linked to activation of M(2)- and M(3)-muscarinic acetylcholine receptors in the rat myometrium
Francis_2000_Mol.Pharmacol_58_109 Subtype-selective inhibition of neuronal nicotinic acetylcholine receptors by cocaine is determined by the alpha4 and beta4 subunits
Grosman_2000_J.Gen.Physiol_115_637 Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist
Grosman_2000_J.Gen.Physiol_115_621 Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: a single-channel study of second transmembrane segment 12' mutants
Grosman_2000_J.Membr.Biol_174_59 Single-channel characterization of a nonselective cation channel from human placental microvillus membranes. Large conductance, multiplicity of conductance states, and inhibition by lanthanides
Grosman_2000_Nature_403_773 Mapping the conformational wave of acetylcholine receptor channel gating
Quik_2000_Neurosci_100_63 Differential alterations in nicotinic receptor alpha6 and beta3 subunit messenger RNAs in monkey substantia nigra after nigrostriatal degeneration
Shao_2000_J.Physiol_527 Pt 3_507 Single channel properties of neuronal nicotinic ACh receptors in stratum radiatum interneurons of rat hippocampal slices
Sudweeks_2000_J.Physiol_527 Pt 3_515 Functional and molecular characterization of neuronal nicotinic ACh receptors in rat CA1 hippocampal neurons
Cho_2000_J.Biol.Chem_275_19942 Phosphorylation of the rat vesicular acetylcholine transporter
Kim_2000_J.Biol.Chem_275_6175 Mutational analysis of basic residues in the rat vesicular acetylcholine transporter. Identification of a transmembrane ion pair and evidence that histidine is not involved in proton translocation
Alami-Durante_2000_J.Exp.Biol_203_3675 Effects of environmental temperature on the development of the myotomal white muscle in larval carp (Cyprinus carpio L.)
Braun_2000_Biochimie_82_705 Myristoylation-dependent N-terminal cleavage of the myristoylated alanine-rich C kinase substrate (MARCKS) by cellular extracts
Ciruela_2000_Mol.Cell.Neurosci_15_36 Homer-1c\/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function
Soloviev_2000_J.Mol.Biol_295_1185 Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing
Soloviev_2000_Eur.J.Biochem_267_634 Mouse brain and muscle tissues constitutively express high levels of Homer proteins
Mike_2000_Brain.Res_882_155 Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons
Aviram_2000_Free.Radic.Res_33 Suppl_S85 Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases
Aviram_2000_Am.J.Clin.Nutr_71_1062 Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice
Aviram_2000_Circulation_101_2510 Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities
Jakubowski_2000_J.Nutr_130_377S Homocysteine thiolactone: metabolic origin and protein homocysteinylation in humans
James_2000_Circulation_101_2252 Smoking is associated with reduced serum paraoxonase activity and concentration in patients with coronary artery disease
James_2000_Diabetes_49_1390 Promoter polymorphism T(-107)C of the paraoxonase PON1 gene is a risk factor for coronary heart disease in type 2 diabetic patients
Leviev_2000_Arterioscler.Thromb.Vasc.Biol_20_516 Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations
Mackness_2000_Clin.Sci.(Lond)_98_355 Low paraoxonase activity in type II diabetes mellitus complicated by retinopathy
Mackness_2000_Biochem.Biophys.Res.Commun_276_729 Low paraoxonase in Persian Gulf War Veterans self-reporting Gulf War Syndrome
MacKness_2000_Eur.J.Clin.Invest_30_4 Paraoxonase activity in two healthy populations with differing rates of coronary heart disease
Meurs_2000_Br.J.Pharmacol_130_1793 Modulation of cholinergic airway reactivity and nitric oxide production by endogenous arginase activity
Navab_2000_J.Lipid.Res_41_1495 Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3
Sundquist_2000_Pharmacol.Toxicol_86_44 Pharmacological characterisation of the enantiomers of BM-5, a muscarinic partial agonist with opposed enantioselectivity between affinity and efficacy
Teiber_2000_Carcinogenesis_21_1559 Identification of the human liver microsomal cytochrome P450s involved in the metabolism of N-nitrosodi-n-propylamine
Bell_2000_Br.J.Pharmacol_131_1135 Histamine depolarizes cholinergic interneurones in the rat striatum via a H(1)-receptor mediated action
Efange_2000_Nucl.Med.Biol_27_749 Synthesis and biological characterization of stable and radioiodinated (+\/-)-trans-2-hydroxy-3-P[4-(3-iodophenyl)piperidyl]-1,2,3,4-tetrahydronaphthalen e (3'-IBVM)
Keller_2000_J.Neurochem_74_1739 Modification of cysteines reveals linkage to acetylcholine and vesamicol binding sites in the vesicular acetylcholine transporter of Torpedo californica
Keller_2000_Neurochem.Int_36_113 A critical histidine in the vesicular acetylcholine transporter
Parsons_2000_FASEB.J_14_2423 Transport mechanisms in acetylcholine and monoamine storage
Preston_2000_Br.J.Pharmacol_130_886 Adenosine receptor expression and function in rat striatal cholinergic interneurons
Preston_2000_Neurosci_95_367 Tachykinins increase [3H]acetylcholine release in mouse striatum through multiple receptor subtypes
Richardson_2000_J.Neurochem_74_839 Correlating physiology with gene expression in striatal cholinergic neurones
Parkhomovskiy_2000_Mol.Cell.Neurosci_15_380 N-acetyllactosamine and the CT carbohydrate antigen mediate agrin-dependent activation of MuSK and acetylcholine receptor clustering in skeletal muscle
Parkhomovskiy_2000_Biochem.Biophys.Res.Commun_270_899 Alpha-galactosidase stimulates acetylcholine receptor aggregation in skeletal muscle cells via PNA-binding carbohydrates
Troy_2000_J.Clin.Psychopharmacol_20_328 Comparison of the effects of zaleplon, zolpidem, and triazolam on memory, learning, and psychomotor performance
Jakubik_2000_J.Biol.Chem_275_18836 Evidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptors
Fujii_2000_Naunyn.Schmiedebergs.Arch.Pharmacol_362_14 Ca2+ oscillation and c-fos gene expression induced via muscarinic acetylcholine receptor in human T- and B-cell lines
Fujii_2000_Jpn.J.Pharmacol_84_124 Calcium signaling and c-Fos gene expression via M3 muscarinic acetylcholine receptors in human T- and B-cells
Fujii_2000_Gen.Pharmacol_35_71 YM905, a novel M3 antagonist, inhibits Ca2+ signaling and c-fos gene expression mediated via muscarinic receptors in human T cells
Grando_2000_Dermatology_201_290 Autoimmunity to keratinocyte acetylcholine receptors in pemphigus
Grando_2000_Arch.Dermatol_136_1269 Nicotine and pemphigus
Harada_2000_Neurosci.Lett_284_163 Enhancement of cerebral cortical acetylcholine release by intraperitoneal acetic acid and its suppression by analgesics in freely moving rats
Nguyen_2000_Am.J.Pathol_157_1377 Novel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunity
Nguyen_2000_J.Biol.Chem_275_29466 Pemphigus vulgaris antibody identifies pemphaxin. A novel keratinocyte annexin-like molecule binding acetylcholine
Nguyen_2000_J.Clin.Invest_106_1467 Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions
Reinheimer_2000_Am.J.Respir.Crit.Care.Med_162_534 Muscarinic control of histamine release from airways. Inhibitory M1-receptors in human bronchi but absence in rat trachea
Zia_2000_J.Pharmacol.Exp.Ther_293_973 Receptor-mediated inhibition of keratinocyte migration by nicotine involves modulations of calcium influx and intracellular concentration
Koenig_2000_Rev.Reprod_5_189 Role of progesterone in peripheral nerve repair
Padilla_2000_Neurotoxicol_21_49 Comparison of the role of esterases in the differential age-related sensitivity to chlorpyrifos and methamidophos
Dubovy_2000_Anat.Embryol.(Berl)_202_235 Restoration of lamellar structures in adult rat Pacinian corpuscles following their simultaneous freezing injury and denervation
Haninec_2000_Ann.Anat_182_123 Acellular nerve graft re-seeded by Schwann cells migrating from the nerve stump can stimulate spinal motoneurons for functional reinnervation of the rat muscle
Ashery_2000_EMBO.J_19_3586 Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cells
Beaumont_2000_Nat.Neurosci_3_133 Enhancement of synaptic transmission by cyclic AMP modulation of presynaptic Ih channels
Bennett_2000_Neuropharmacol_39_523 The concept of transmitter receptors: 100 years on
Chamaon_2000_FEBS.Lett_482_189 Neuronal nicotinic acetylcholine receptors of Drosophila melanogaster: the alpha-subunit dalpha3 and the beta-type subunit ARD co-assemble within the same receptor complex
Chanas-Sacre_2000_Dev.Dyn_219_514 A 295-kDA intermediate filament-associated protein in radial glia and developing muscle cells in vivo and in vitro
Chapman_2000_Neurosci_97_419 Reversal of presynaptic deficits of apolipoprotein E-deficient mice in human apolipoprotein E transgenic mice
Daly_2000_Proc.Natl.Acad.Sci.U.S.A_97_6120 Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles
Dineley_2000_J.Biol.Chem_275_13974 Amino acid determinants of alpha 7 nicotinic acetylcholine receptor surface expression
Faundez_2000_Mol.Biol.Cell_11_2591 The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform
Fisher_2000_Ann.N.Y.Acad.Sci_920_315 M1 muscarinic agonists as potential disease-modifying agents in Alzheimer's disease. Rationale and perspectives
Fostieri_2000_FEBS.Lett_481_127 The conformation of the main immunogenic region on the alpha-subunit of muscle acetylcholine receptor is affected by neighboring receptor subunits
Fukuda_2000_Proc.Natl.Acad.Sci.U.S.A_97_14715 Role of the conserved WHXL motif in the C terminus of synaptotagmin in synaptic vesicle docking
Garner_2000_Curr.Opin.Neurobiol_10_321 Molecular determinants of presynaptic active zones
Gundelfinger_2000_Naturwiss_87_513 Molecular organization of excitatory chemical synapses in the mammalian brain
Hess_2000_Proc.Natl.Acad.Sci.U.S.A_97_13895 Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801
Hung_2000_Fundam.Clin.Pharmacol_14_387 Identification of opioid receptors in the sympathetic and parasympathetic nerves of guinea-pig atria
Katz_2000_Hear.Res_141_117 High calcium permeability and calcium block of the alpha9 nicotinic acetylcholine receptor
Kleinjung_2000_Biopolymers_53_113 The third-dimensional structure of the complex between an Fv antibody fragment and an analogue of the main immunogenic region of the acetylcholine receptor: a combined two-dimensional NMR, homology, and molecular modeling approach
Kontou_2000_Eur.J.Biochem_267_2389 The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor
Kwan_2000_Zhonghua.Yi.Xue.Za.Zhi.(Taipei)_63_153 Coexistence of epilepsy, myasthenia gravis and psoriasis vulgaris
Lupardus_2000_J.Physiol_526 Pt 3_527 Membrane-delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G-protein nor ATP
Marrs_2000_Food.Addit.Contam_17_487 The health significance of pesticide variability in individual commodity items
Neumann_2000_Bioelectrochemistry_52_43 Digression on chemical electromagnetic field effects in membrane signal transduction--cooperativity paradigm of the acetylcholine receptor
Orr-Urtreger_2000_J.Neurochem_74_2154 Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth
Papanastasiou_2000_J.Neuroimmunol_104_124 Prevention of passively transferred experimental autoimmune myasthenia gravis by Fab fragments of monoclonal antibodies directed against the main immunogenic region of the acetylcholine receptor
Poulas_2000_Clin.Exp.Immunol_120_363 Treatment of passively transferred experimental autoimmune myasthenia gravis using papain
Prior_2000_Br.J.Pharmacol_129_1067 Factors influencing the low-frequency associated nicotinic ACh autoreceptor-mediated depression of ACh release from rat motor nerve terminals
Qualmann_2000_J.Cell.Biol_148_1047 Syndapin isoforms participate in receptor-mediated endocytosis and actin organization
Roos_2000_Nat.Neurosci_3_415 Preassembly and transport of nerve terminals: a new concept of axonal transport
Rothlin_2000_Neuropharmacol_39_2525 Block of the alpha9 nicotinic receptor by ototoxic aminoglycosides
Schneggenburger_2000_Nature_406_889 Intracellular calcium dependence of transmitter release rates at a fast central synapse
Schulz_2000_J.Neurochem_74_2537 Neuronal nicotinic acetylcholine receptors from Drosophila: two different types of alpha subunits coassemble within the same receptor complex
Schwarz_2000_Eur.J.Neurosci_12_3107 Different functions of fetal and adult AChR subtypes for the formation and maintenance of neuromuscular synapses revealed in epsilon-subunit-deficient mice
Sieb_2000_Ann.Neurol_48_379 Severe congenital myasthenic syndrome due to homozygosity of the 1293insG epsilon-acetylcholine receptor subunit mutation
Tang_2000_Biophys.J_78_2735 Effects of mobile buffers on facilitation: experimental and computational studies
Thomas_2000_Curr.Biol_10_1108 Synaptic targeting and localization of discs-large is a stepwise process controlled by different domains of the protein
Trinidad_2000_J.Neurosci_20_8762 The Agrin\/MuSK signaling pathway is spatially segregated from the neuregulin\/ErbB receptor signaling pathway at the neuromuscular junction
Tsouloufis_2000_Int.Immunol_12_1255 Reconstitution of conformationally dependent epitopes on the N-terminal extracellular domain of the human muscle acetylcholine receptor alpha subunit expressed in Escherichia coli: implications for myasthenia gravis therapeutic approaches
Yao_2000_J.Neurosci_20_2626 Spontaneous acetylcholine secretion from developing growth cones of Drosophila central neurons in culture: effects of cAMP-pathway mutations
Zhai_2000_Mol.Cell.Neurosci_15_417 Temporal appearance of the presynaptic cytomatrix protein bassoon during synaptogenesis
Oh_2000_Brain.Res_853_174 Overexpression of neurotrophin receptor p75 contributes to the excitotoxin-induced cholinergic neuronal death in rat basal forebrain
Li_2000_J.Neurochem_75_1320 Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse
Lukomskaya_2000_Neurosci.Behav.Physiol_30_543 The involvement of glutamatergic transmission in the mechanism of movement disorders induced by reversive rotation of white mice
Hein_2000_Drug.Metab.Dispos_28_1425 Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber
Burgen_2000_Annu.Rev.Pharmacol.Toxicol_40_1 Targets of drug action
Cape_2000_J.Neurosci_20_8452 Neurotensin-induced bursting of cholinergic basal forebrain neurons promotes gamma and theta cortical activity together with waking and paradoxical sleep
Maloney_2000_J.Neurosci_20_4669 c-Fos expression in GABAergic, serotonergic, and other neurons of the pontomedullary reticular formation and raphe after paradoxical sleep deprivation and recovery
Manns_2000_J.Neurosci_20_9252 Discharge profiles of juxtacellularly labeled and immunohistochemically identified GABAergic basal forebrain neurons recorded in association with the electroencephalogram in anesthetized rats
Manns_2000_J.Neurosci_20_1505 Discharge properties of juxtacellularly labeled and immunohistochemically identified cholinergic basal forebrain neurons recorded in association with the electroencephalogram in anesthetized rats
Materi_2000_Neurosci_97_219 Inhibition of synaptically evoked cortical acetylcholine release by adenosine: an in vivo microdialysis study in the rat
Rasmusson_2000_Behav.Brain.Res_115_205 The role of acetylcholine in cortical synaptic plasticity
Reuben_2000_Neuropharmacol_39_290 Nicotine-evoked [3H]5-hydroxytryptamine release from rat striatal synaptosomes
Tremere_2000_Neuroreport_11_2177 Antibody for human p75 LNTR identifies cholinergic basal forebrain of non-primate species
Sacchettini_2000_Trends.Microbiol_8_441 The mycobacterial antigens 85 complex--from structure to function: response
Balestra_2000_J.Neuroimmunol_102_89 Antibodies against neuronal nicotinic receptor subtypes in neurological disorders
Balestra_2000_Mol.Pharmacol_58_300 Chick optic lobe contains a developmentally regulated alpha2alpha5beta2 nicotinic receptor subtype
Benhammou_2000_Neuropharmacol_39_2818 [(3)H]Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day
Clementi_2000_Trends.Pharmacol.Sci_21_35 Neuronal nicotinic acetylcholine receptors: from structure to therapeutics
Conroy_2000_Neuropharmacol_39_2699 Cluster formation of alpha7-containing nicotinic receptors at interneuronal interfaces in cell culture
Cuevas_2000_J.Physiol_525 Pt 3_735 Two distinct classes of functional 7-containing nicotinic receptor on rat superior cervical ganglion neurons
Dajas-Bailador_2000_Neuropharmacol_39_2799 The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism
Dani_2000_Epilepsia_41_1063 Properties underlying the influence of nicotinic receptors on neuronal excitability and epilepsy
Dani_2000_Eur.J.Pharmacol_393_31 Variations in desensitization of nicotinic acetylcholine receptors from hippocampus and midbrain dopamine areas
File_2000_Eur.J.Pharmacol_393_231 Neurobiological mechanisms by which nicotine mediates different types of anxiety
Fisher_2000_Neuropharmacol_39_2756 Nicotinic receptors on hippocampal cultures can increase synaptic glutamate currents while decreasing the NMDA-receptor component
George_2000_J.Pharmacol.Exp.Ther_295_58 Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization
Girod_2000_Neuropharmacol_39_2715 Facilitation of glutamatergic neurotransmission by presynaptic nicotinic acetylcholine receptors
Gotti_2000_Behav.Brain.Res_113_183 Drugs selective for nicotinic receptor subtypes: a real possibility or a dream?
Hicks_2000_J.Physiol_529 Pt 3_579 Regulation of the sensitivity of acetylcholine receptors to nicotine in rat habenula neurons
Ji_2000_J.Neurophysiol_83_2682 Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons
Kaiser_2000_Mol.Pharmacol_58_312 alpha-bungarotoxin-sensitive nicotinic receptors indirectly modulate [(3)H]dopamine release in rat striatal slices via glutamate release
Lioudyno_2000_Hear.Res_149_167 Morphine inhibits an alpha9-acetylcholine nicotinic receptor-mediated response by a mechanism which does not involve opioid receptors
Marks_2000_Neuropharmacol_39_2632 Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype
Martin-Ruiz_2000_Neuropharmacol_39_2830 Alpha and beta nicotinic acetylcholine receptors subunits and synaptophysin in putamen from Parkinson's disease
Mukhin_2000_Mol.Pharmacol_57_642 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors
Paysan_2000_J.Comp.Neurol_425_284 The neurofilament infrastructure of a developing presynaptic calyx
Picciotto_2000_Neuropsychopharmacology_22_451 Nicotinic receptors in the brain. Links between molecular biology and behavior
Sharples_2000_J.Neurosci_20_2783 UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes
Shoop_2000_J.Neurosci_20_4021 Cytoskeletal links of neuronal acetylcholine receptors containing alpha 7 subunits
Tierney_2000_J.Mol.Biol_303_185 Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor
Verbitsky_2000_Neuropharmacol_39_2515 Mixed nicotinic-muscarinic properties of the alpha9 nicotinic cholinergic receptor
Weill_2000_Anal.Biochem_285_267 Quantitative polymerase chain reaction to estimate the number of amplified esterase genes in insecticide-resistant mosquitoes
Weill_2000_Insect.Mol.Biol_9_451 The kdr mutation occurs in the Mopti form of Anopheles gambiae s.s. through introgression
Whiteaker_2000_Eur.J.Pharmacol_393_123 Pharmacological and null mutation approaches reveal nicotinic receptor diversity
Wolpowitz_2000_Neuron_25_79 Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses
Wonnacott_2000_Eur.J.Pharmacol_393_51 Presynaptic nicotinic receptors modulating dopamine release in the rat striatum
Adams_2000_J.Neurochem_75_2277 The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK
Baenziger_2000_J.Biol.Chem_275_777 Effect of membrane lipid composition on the conformational equilibria of the nicotinic acetylcholine receptor
Barrantes_2000_Kidney.Int_57_1382 Nongenomic effects of steroids on the nicotinic acetylcholine receptor
Bouzat_2000_J.Gen.Physiol_115_663 Nicotinic receptor fourth transmembrane domain: hydrogen bonding by conserved threonine contributes to channel gating kinetics
Breese_2000_Neuropsychopharmacology_23_351 Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia
Breeze_2000_Neuropharmacol_39_2706 Optical measurements of presynaptic nicotinic effects
Buisson_2000_Neuropharmacol_39_2561 The unusual nature of epibatidine responses at the alpha4beta2 nicotinic acetylcholine receptor
Culetto_2000_Hum.Mol.Genet_9_869 A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes
Damaj_2000_Eur.J.Pharmacol_404_103 The involvement of spinal Ca(2+)\/calmodulin-protein kinase II in nicotine-induced antinociception in mice
Damaj_2000_Neuropharmacol_39_2785 The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model
Drisdel_2000_J.Neurosci_20_133 Neuronal alpha-bungarotoxin receptors are alpha7 subunit homomers
Ferretti_2000_Bioorg.Med.Chem.Lett_10_2665 Chain-lengthened and imidazoline analogues of nicotine
Freedman_2000_Am.J.Med.Genet_97_58 Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia
Freedman_2000_J.Chem.Neuroanat_20_299 The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia
Gommans_2000_Neuropharmacol_39_2840 Antagonism of the discriminative and aversive stimulus properties of nicotine in C57BL\/6J mice
Hahn_2000_Neuropharmacol_39_2848 Kappa-opioid receptor modulation of nicotine-induced behaviour
Keyser_2000_Vis.Neurosci_17_743 Amacrine, ganglion, and displaced amacrine cells in the rabbit retina express nicotinic acetylcholine receptors
Leonard_2000_Eur.J.Pharmacol_393_237 Smoking and schizophrenia: abnormal nicotinic receptor expression
Lindstrom_2000_Muscle.Nerve_23_453 Acetylcholine receptors and myasthenia
Mansvelder_2000_Neuron_27_349 Long-term potentiation of excitatory inputs to brain reward areas by nicotine
Marenco_2000_Br.J.Pharmacol_129_147 Effects of nicotine and chlorisondamine on cerebral glucose utilization in immobilized and freely-moving rats
Matsuda_2000_Br.J.Pharmacol_130_981 Role of loop D of the alpha7 nicotinic acetylcholine receptor in its interaction with the insecticide imidacloprid and related neonicotinoids
McCallum_2000_Psychopharmacology.(Berl)_150_1 Mecamylamine prevents tolerance but enhances whole brain [3H]epibatidine binding in response to repeated nicotine administration in rats
Narahashi_2000_Toxicol.Sci_57_193 Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior
Raymond_2000_Neurosci_101_785 Anthelmintic actions on homomer-forming nicotinic acetylcholine receptor subunits: chicken alpha7 and ACR-16 from the nematode Caenorhabditis elegans
Shoaib_2000_Psychopharmacology.(Berl)_149_140 Antagonism of stimulus properties of nicotine by dihydro-beta-erythroidine (DHbetaE) in rats
Slemmer_2000_J.Pharmacol.Exp.Ther_295_321 Bupropion is a nicotinic antagonist
Stolerman_2000_Eur.J.Pharmacol_393_147 Nicotine in an animal model of attention
Torrao_2000_Brain.Res_863_249 Effects of cholinergic deafferentation upon the expression of the alpha2 subunit of the nicotinic acetylcholine receptors in the chick lateral spiriform nucleus
Weiland_2000_Behav.Brain.Res_113_43 Neuronal nicotinic acetylcholine receptors: from the gene to the disease
Zubaran_2000_Behav.Pharmacol_11_431 The development and expression of locomotor sensitization to nicotine in the presence of ibogaine
Alkondon_2000_Eur.J.Pharmacol_393_59 alpha7 nicotinic acetylcholine receptors and modulation of gabaergic synaptic transmission in the hippocampus
Bunnemann_2000_Eur.J.Pharmacol_393_249 Chronic nicotine treatment decreases neurofilament immunoreactivity in the rat ventral tegmental area
Cadoni_2000_Eur.J.Pharmacol_387_R23 Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine
Carboni_2000_Drug.Alcohol.Depend_58_93 Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats
Carboni_2000_J.Neurosci_20_RC102 Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs
Cheeta_2000_Prog.Neuropsychopharmacol.Biol.Psychiatry_24_1053 Hippocampal and septal injections of nicotine and 8-OH-DPAT distinguish among different animal tests of anxiety
Cheeta_2000_Eur.J.Neurosci_12_3797 The role of 5-HT1A receptors in mediating the anxiogenic effects of nicotine following lateral septal administration
Clementi_2000_Eur.J.Pharmacol_393_1 Special issue nicotinic neuronal receptors
Conti-Fine_2000_Eur.J.Pharmacol_393_279 Neuronal nicotinic receptors in non-neuronal cells: new mediators of tobacco toxicity?
Curtis_2000_Eur.J.Pharmacol_393_155 A new look at the neuronal nicotinic acetylcholine receptor pharmacophore
De Biasi_2000_Eur.J.Pharmacol_393_137 Nicotinic acetylcholine receptors in the autonomic control of bladder function
Deneris_2000_Eur.J.Pharmacol_393_69 Transcriptional control of the neuronal nicotinic acetylcholine receptor gene cluster by the beta43' enhancer, Sp1, SCIP and ETS transcription factors
Di Chiara_2000_Eur.J.Pharmacol_393_295 Role of dopamine in the behavioural actions of nicotine related to addiction
Erkman_2000_Eur.J.Pharmacol_393_97 Nicotinic acetylcholine receptor gene expression in developing chick autonomic ganglia
File_2000_Pharmacol.Biochem.Behav_66_65 The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety
Flora_2000_Eur.J.Pharmacol_393_85 Transcriptional regulation of the human alpha5 nicotinic receptor subunit gene in neuronal and non-neuronal tissues
Hellstrom-Lindahl_2000_Eur.J.Pharmacol_393_255 Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors
Kenny_2000_Neuropharmacol_39_300 Anxiogenic effects of nicotine in the dorsal hippocampus are mediated by 5-HT1A and not by muscarinic M1 receptors
Kenny_2000_Brain.Res.Mol.Brain.Res_85_234 Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus
Kuryatov_2000_Eur.J.Pharmacol_393_11 Acetylcholine receptor extracellular domain determines sensitivity to nicotine-induced inactivation
Levin_2000_Eur.J.Pharmacol_393_141 Development of nicotinic drug therapy for cognitive disorders
Marubio_2000_Eur.J.Pharmacol_393_113 Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function
McIntosh_2000_Eur.J.Pharmacol_393_205 Conus peptides: novel probes for nicotinic acetylcholine receptor structure and function
Melnikova_2000_Eur.J.Pharmacol_393_75 Interactions between regulatory proteins that bind to the nicotinic receptor beta4 subunit gene promoter
Meyer_2000_Eur.J.Pharmacol_393_171 The identification of novel structural compound classes exhibiting high affinity for neuronal nicotinic acetylcholine receptors and analgesic efficacy in preclinical models of pain
Papke_2000_Eur.J.Pharmacol_393_179 alpha7 receptor-selective agonists and modes of alpha7 receptor activation
Quik_2000_Eur.J.Pharmacol_393_223 Nicotinic receptors and Parkinson's disease
Reuben_2000_Eur.J.Pharmacol_393_39 Nicotinic receptors modulating somatodendritic and terminal dopamine release differ pharmacologically
Schuller_2000_Eur.J.Pharmacol_393_265 Interaction of tobacco-specific toxicants with the neuronal alpha(7) nicotinic acetylcholine receptor and its associated mitogenic signal transduction pathway: potential role in lung carcinogenesis and pediatric lung disorders
Steinlein_2000_Eur.J.Pharmacol_393_243 Neuronal nicotinic receptors in human epilepsy
Yokoo_2000_Brain.Res_873_149 Inhibition by neuroprotective drug NS-7 of nicotine-induced 22Na(+) influx, 45Ca(2+) influx and catecholamine secretion in adrenal chromaffin cells
Zwart_2000_Eur.J.Pharmacol_393_209 Potentiation and inhibition of neuronal alpha4beta4 nicotinic acetylcholine receptors by choline
Walsh_2000_Mol.Cell.Neurosci_15_244 Ectopic expression of NCAM in skeletal muscle of transgenic mice results in terminal sprouting at the neuromuscular junction and altered structure but not function
Rafuse_2000_J.Neurosci_20_1056 The pattern of avian intramuscular nerve branching is determined by the innervating motoneuron and its level of polysialic acid
Rafuse_2000_J.Neurosci_20_6529 Structural and functional alterations of neuromuscular junctions in NCAM-deficient mice
Budd_2000_J.Biol.Chem_275_19667 Phosphorylation and regulation of a Gq\/11-coupled receptor by casein kinase 1alpha
Messer_2000_Pharm.Acta.Helv_74_135 Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors
Song_2000_J.Neurophysiol_83_322 Adenosine receptor expression and modulation of Ca(2+) channels in rat striatal cholinergic interneurons
Abi-Gerges_2000_J.Physiol_523 Pt 2_377 Functional expression and regulation of the hyperpolarization activated non-selective cation current in embryonic stem cell-derived cardiomyocytes
Barnes_2000_Chest_117_63S The pharmacological properties of tiotropium
Belmonte_2000_J.Neurosci_20_8417 Developmental expression of muscarinic acetylcholine receptors in chick retina: selective induction of M2 muscarinic receptor expression in ovo by a factor secreted by muller glial cells
Blomquist_2000_Biochem.J_352 Pt 2_319 Identification and characterization of a novel Rho-specific guanine nucleotide exchange factor
Carsi_2000_Toxicon_38_187 m1-toxin isotoxins from the green mamba (Dendroaspis angusticeps) that selectively block m1 muscarinic receptors
Creason_2000_J.Neurochem_74_882 Isolation and functional characterization of the chick M5 muscarinic acetylcholine receptor gene
Fatani_2000_Toxicon_38_1787 The effects of lignocaine on actions of the venom from the yellow scorpion Leiurus quinquestriatus in vivo and in vitro
Finney_2000_J.Clin.Invest_106_125 Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo
Fukuhara_2000_J.Biol.Chem_275_21730 Signaling from G protein-coupled receptors to ERK5\/Big MAPK 1 involves Galpha q and Galpha 12\/13 families of heterotrimeric G proteins. Evidence for the existence of a novel Ras AND Rho-independent pathway
Greenberg_2000_Arch.Neurol_57_94 Donepezil therapy in clinical practice: a randomized crossover study
Hellgren_2000_Cell.Mol.Life.Sci_57_175 Muscarinic M3 receptor subtype gene expression in the human heart
Himmel_2000_Mol.Pharmacol_58_449 Evidence for Edg-3 receptor-mediated activation of I(K.ACh) by sphingosine-1-phosphate in human atrial cardiomyocytes
Hock_2000_Ann.N.Y.Acad.Sci_920_285 Treatment with the selective muscarinic agonist talsaclidine decreases cerebrospinal fluid levels of total amyloid beta-peptide in patients with Alzheimer's disease
Jerusalinsky_2000_Toxicon_38_747 Muscarinic toxins: novel pharmacological tools for the muscarinic cholinergic system
Karlsson_2000_Biochimie_82_793 Snake toxins with high selectivity for subtypes of muscarinic acetylcholine receptors
Krudewig_2000_J.Neurochem_74_1721 Distinct internalization of M2 muscarinic acetylcholine receptors confers selective and long-lasting desensitization of signaling to phospholipase C
Leckie_2000_Expert.Opin.Investig.Drugs_9_3 Novel therapy for COPD
Nasman_2000_Biochem.Biophys.Res.Commun_271_435 Recombinant expression of a selective blocker of M(1) muscarinic receptors
Nathanson_2000_Proc.Natl.Acad.Sci.U.S.A_97_6245 A multiplicity of muscarinic mechanisms: enough signaling pathways to take your breath away
Nitsch_2000_Ann.Neurol_48_913 The selective muscarinic M1 agonist AF102B decreases levels of total Abeta in cerebrospinal fluid of patients with Alzheimer's disease
Olianas_2000_Br.J.Pharmacol_131_447 Inhibition of acetylcholine muscarinic M(1) receptor function by the M(1)-selective ligand muscarinic toxin 7 (MT-7)
Rasmussen_2000_Eur.J.Pharmacol_402_241 Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice
Rouse_2000_Neurosci.Lett_278_61 Muscarinic-induced modulation of potassium conductances is unchanged in mouse hippocampal pyramidal cells that lack functional M1 receptors
Schlador_2000_J.Biol.Chem_275_23295 Multiple topological domains mediate subtype-specific internalization of the M2 muscarinic acetylcholine receptor
Schmidt_2000_J.Biol.Chem_275_32603 G protein-coupled receptor-induced sensitization of phospholipase C stimulation by receptor tyrosine kinases
Shannon_2000_Schizophr.Res_42_249 Xanomeline, an M(1)\/M(4) preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice
Spicuzza_2000_Br.J.Pharmacol_130_1720 Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves
Werbonat_2000_J.Biol.Chem_275_21969 Essential role of dynamin in internalization of M2 muscarinic acetylcholine and angiotensin AT1A receptors
Womer_2000_Neuropharmacol_39_2499 Reversal of pertussis toxin-induced thermal allodynia by muscarinic cholinergic agonists in mice
Yeomans_2000_J.Neurosci_20_8861 Brain-stimulation reward thresholds raised by an antisense oligonucleotide for the M5 muscarinic receptor infused near dopamine cells
Zholos_2000_J.Physiol_528_521 Membrane currents in cultured human intestinal smooth muscle cells
Zholos_2000_Br.J.Pharmacol_129_695 Voltage-dependent inhibition of the muscarinic cationic current in guinea-pig ileal cells by SK&\;F 96365
Akici_2000_Eur.J.Pharmacol_388_115 Further evidence for the heterogeneity of functional muscarinic receptors in guinea pig gallbladder
Auld_2000_J.Pharmacol.Exp.Ther_292_692 Pharmacological characterization of endogenous acetylcholine release from primary septal cultures
Bellingham_2000_Clin.Exp.Pharmacol.Physiol_27_132 Cholinergic modulation of respiratory brain-stem neurons and its function in sleep-wake state determination
Biagioni_2000_J.Neurosci.Res_62_591 Modulation of cholinergic marker expression by nerve growth factor in dorsal root ganglia
Biagioni_2000_Int.J.Dev.Biol_44_689 Acetylcholine synthesis and neuron differentiation
Botero Cid_2000_J.Med.Chem_43_2155 Structure-activity relationships in a series of bisquaternary bisphthalimidine derivatives modulating the muscarinic M(2)-receptor allosterically
Chan_2000_Toxicol.Appl.Pharmacol_167_231 Lidocaine-induced alterations in agonist-induced ion transport of cultured swine tracheal submucosal gland cells
Christopoulos_2000_J.Pharmacol.Toxicol.Methods_43_55 Transducer abstraction: a novel approach to the detection of partial agonist efficacy in radioligand binding studies
Coronas_2000_Neurosci_98_213 Acetylcholine induces neuritic outgrowth in rat primary olfactory bulb cultures
Costello_2000_Histol.Histopathol_15_861 Eosinophils and airway nerves in asthma
D'Agostino_2000_Br.J.Pharmacol_129_493 Prejunctional muscarinic inhibitory control of acetylcholine release in the human isolated detrusor: involvement of the M4 receptor subtype
Darroch_2000_Eur.J.Pharmacol_402_161 Characterisation of muscarinic receptor subtypes in avian smooth muscle
Eatman_2000_J.Pharmacol.Toxicol.Methods_44_533 Phenotypic stability of chick cardiomyocytes in serum-free media. Preservation of muscarinic receptor expression
Evans_2000_Am.J.Physiol.Lung.Cell.Mol.Physiol_279_L477 Substance P-induced airway hyperreactivity is mediated by neuronal M(2) receptor dysfunction
Hersi_2000_Brain.Res.Mol.Brain.Res_76_336 Dopamine D-5 receptor modulates hippocampal acetylcholine release
Hirabayashi_2000_Eur.J.Biochem_267_2525 M1 muscarinic acetylcholine receptors activate zif268 gene expression via small G-protein Rho-dependent and lambda-independent pathways in PC12D cells
Hoglund_2000_J.Pharmacol.Exp.Ther_295_100 Effects of microdialyzed oxotremorine, carbachol, epibatidine, and scopolamine on intraspinal release of acetylcholine in the rat
Holz_2000_J.Biol.Chem_275_17878 A pleckstrin homology domain specific for phosphatidylinositol 4, 5-bisphosphate (PtdIns-4,5-P2) and fused to green fluorescent protein identifies plasma membrane PtdIns-4,5-P2 as being important in exocytosis
Jacoby_2000_Am.J.Physiol.Lung.Cell.Mol.Physiol_279_L59 Effects of neurokinin receptor antagonists in virus-infected airways
Lambrecht_2000_Eur.J.Pharmacol_387_R19 The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X(1) receptors
Landry_2000_Rev.Mal.Respir_17_539 [Control of bronchial contractility, regulation of receptor activity and expression]
Lau_2000_Br.J.Pharmacol_130_1013 Cholinergic facilitation of neurotransmission to the smooth muscle of the guinea-pig prostate gland
Lee_2000_J.Biol.Chem_275_35767 Acidic amino acids flanking phosphorylation sites in the M2 muscarinic receptor regulate receptor phosphorylation, internalization, and interaction with arrestins
Lee_2000_J.Biol.Chem_275_9284 Arrestin binding to the M(2) muscarinic acetylcholine receptor is precluded by an inhibitory element in the third intracellular loop of the receptor
Linseman_2000_J.Neurochem_74_2010 A role for the small molecular weight GTPases, Rho and Cdc42, in muscarinic receptor signaling to focal adhesion kinase
Novak_2000_Neurochem.Res_25_561 Regulation of Myo-inositol homeostasis in differentiated human NT2-N neurons
Pfaffendorf_2000_J.Auton.Pharmacol_20_55 Probing the selectivity of allosteric modulators of muscarinic receptors at other G-protein-coupled receptors
Sawyer_2000_Br.J.Pharmacol_129_1458 Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum
Sternini_2000_Neurosci_98_233 Role of agonist-dependent receptor internalization in the regulation of mu opioid receptors
Tata_2000_Brain.Res_866_65 Muscarinic receptors modulate intracellular calcium level in chick sensory neurons
Tsuga_2000_Neurotoxicol.Teratol_22_603 Effects of short-term toluene exposure on ligand binding to muscarinic acetylcholine receptors in the rat frontal cortex and hippocampus
Tumiatti_2000_Arzneimittelforschung_50_11 Muscarinic properties of compounds related to arecaidine propargyl ester
Galeazzi_2000_Am.J.Physiol.Gastrointest.Liver.Physiol_278_G259 Inflammation-induced impairment of enteric nerve function in nematode-infected mice is macrophage dependent
Prins_2000_Br.J.Pharmacol_129_1601 An improved in vitro bioassay for the study of 5-HT(4) receptors in the human isolated large intestinal circular muscle
Richelson_2000_Life.Sci_68_29 Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds
Wang_2000_Am.J.Physiol.Gastrointest.Liver.Physiol_279_G1059 Human esophageal smooth muscle cells express muscarinic receptor subtypes M(1) through M(5)
Wong_2000_Biol.Psychiatry_47_818 Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor
Elhusseiny_2000_J.Cereb.Blood.Flow.Metab_20_298 Muscarinic--but not nicotinic--acetylcholine receptors mediate a nitric oxide-dependent dilation in brain cortical arterioles: a possible role for the M5 receptor subtype
Hayashi_2000_Gene.Ther_7_1664 In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model
Heijenbrok_2000_Naunyn.Schmiedebergs.Arch.Pharmacol_362_504 The influence of chronic inhibition of nitric oxide synthesis on contractile and relaxant properties of rat carotid and mesenteric arteries
Kikusui_2000_Pharmacol.Biochem.Behav_65_131 The allocentric place discrimination task is selectively and highly dependent on the central muscarinic system in rats
Lin_2000_Dig.Dis.Sci_45_1517 Alterations of GTP-binding proteins (Gsalpha and Gq\/11alpha) in gastric smooth muscle cells from streptozotocin-induced and WBN\/Kob diabetic rats
Mufson_2000_Neuropharmacol_39_1404 Galanin receptor plasticity within the nucleus basalis in early and late Alzheimer's disease: an in vitro autoradiographic analysis
Selyanko_2000_J.Physiol_522 Pt 3_349 Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors
Tecle_2000_Pharm.Acta.Helv_74_141 CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology
Tomita_2000_Keio.J.Med_49_26 Regulation of cerebral microcirculation--update
Tong_2000_Eur.J.Neurosci_12_2769 Basal forebrain nitric oxide synthase (NOS)-containing neurons project to microvessels and NOS neurons in the rat neocortex: cellular basis for cortical blood flow regulation
Zaltsman_2000_Br.J.Pharmacol_130_315 Rapid desensitization of the TRH receptor and persistent desensitization of its constitutively active mutant
Angeli_2000_Pharm.Acta.Helv_74_131 Receptors in neurodegenerative diseases, muscarinic cholinergic receptors
Bartolomeo_2000_J.Pharmacol.Exp.Ther_292_584 The preclinical pharmacological profile of WAY-132983, a potent M1 preferring agonist
De Amici_2000_Farmaco_55_535 Synthesis and pharmacological characterization of new chiral derivatives of muscarine and allo-muscarine
Gualtieri_2000_Pharm.Acta.Helv_74_85 Cholinergic receptors and neurodegenerative diseases
Hellstrom-Lindahl_2000_Behav.Brain.Res_113_159 Nicotinic acetylcholine receptors during prenatal development and brain pathology in human aging
Pemberton_2000_Pflugers.Arch_440_452 Modulation of low-threshold T-type calcium channels by the five muscarinic receptor subtypes in NIH 3T3 cells
Alberi_2000_Brain.Res_872_11 Involvement of calmodulin-dependent protein kinase II in carbachol-induced rhythmic activity in the hippocampus of the rat
Murthy_2000_Am.J.Physiol.Cell.Physiol_279_C925 Heterologous desensitization of response mediated by selective PKC-dependent phosphorylation of G(i-1) and G(i-2)
Murthy_2000_J.Biol.Chem_275_30211 Heterologous desensitization mediated by G protein-specific binding to caveolin
Scheschonka_2000_Mol.Pharmacol_58_719 RGS3 is a GTPase-activating protein for g(ialpha) and g(qalpha) and a potent inhibitor of signaling by GTPase-deficient forms of g(qalpha) and g(11alpha)
Stromgaard_2000_J.Med.Chem_43_4526 Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues
Boyle_2000_Bioorg.Med.Chem.Lett_10_2727 Benzylidene ketal derivatives as M2 muscarinic receptor antagonists
Carlson_2000_Pharmacol.Biochem.Behav_65_683 Effects of H1 antagonists on cholinomimetic-induced tremulous jaw movements: studies of diphenhydramine, doxepin, and mepyramine
Kozlowski_2000_Bioorg.Med.Chem.Lett_10_2255 Diphenyl sulfoxides as selective antagonists of the muscarinic M2 receptor
Shapiro_2000_J.Neurosci_20_1710 Reconstitution of muscarinic modulation of the KCNQ2\/KCNQ3 K(+) channels that underlie the neuronal M current
Wang_2000_Bioorg.Med.Chem.Lett_10_2247 Design and synthesis of piperidinyl piperidine analogues as potent and selective M2 muscarinic receptor antagonists
Bender_2000_Life.Sci_66_1675 Probing the size of a hydrophobic binding pocket within the allosteric site of muscarinic acetylcholine M2-receptors
Forster_2000_Eur.J.Neurosci_12_3596 Laterodorsal tegmental stimulation elicits dopamine efflux in the rat nucleus accumbens by activation of acetylcholine and glutamate receptors in the ventral tegmental area
Holzgrabe_2000_Pharm.Acta.Helv_74_149 Ligands for the common allosteric site of acetylcholine M2-receptors: development and application
Bitner_2000_Brain.Res_871_66 Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat
Corrigall_2000_Psychopharmacology.(Berl)_149_107 Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental area
Donny_2000_Eur.J.Pharmacol_402_231 Differential effects of response-contingent and response-independent nicotine in rats
Donny_2000_Psychopharmacology.(Berl)_151_392 Nicotine self-administration in rats: estrous cycle effects, sex differences and nicotinic receptor binding
Green_2000_Psychopharmacology.(Berl)_152_289 Nornicotine pretreatment decreases intravenous nicotine self-administration in rats
Grottick_2000_J.Pharmacol.Exp.Ther_294_1112 Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine
Horti_2000_Life.Sci_67_463 6-[18F]fluoro-A-85380, a novel radioligand for in vivo imaging of central nicotinic acetylcholine receptors
Jose_2000_Neuropharmacol_39_2808 Nicotine-induced fos expression in the pedunculopontine mesencephalic tegmentum in the rat
Kelton_2000_Brain.Cogn_43_274 The effects of nicotine on Parkinson's disease
Lanca_2000_Neurosci_96_735 The pedunculopontine tegmental nucleus and the role of cholinergic neurons in nicotine self-administration in the rat: a correlative neuroanatomical and behavioral study
Le_2000_Alcohol.Clin.Exp.Res_24_155 Involvement of nicotinic receptors in alcohol self-administration
Miller_2000_Neuropharmacol_39_2654 Lobeline inhibits nicotine-evoked [(3)H]dopamine overflow from rat striatal slices and nicotine-evoked (86)Rb(+) efflux from thalamic synaptosomes
Newhouse_2000_Pharm.Acta.Helv_74_91 Nicotinic systems in central nervous systems disease: degenerative disorders and beyond
Pogun_2000_Eur.Neuropsychopharmacol_10_463 Nicotine modulates nitric oxide in rat brain
Rusted_2000_Behav.Brain.Res_113_121 Nicotinic treatment for degenerative neuropsychiatric disorders such as Alzheimer's disease and Parkinson's disease
Scheffel_2000_Nucl.Med.Biol_27_51 6-[18F]Fluoro-A-85380: an in vivo tracer for the nicotinic acetylcholine receptor
Sihver_2000_Behav.Brain.Res_113_143 Development of ligands for in vivo imaging of cerebral nicotinic receptors
Waldo_2000_Biol.Psychiatry_47_231 Familial transmission of risk factors in the first-degree relatives of schizophrenic people
Watkins_2000_J.Pharmacol.Exp.Ther_292_1053 Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects
Cadenhead_2000_Am.J.Psychiatry_157_55 Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder
Briguet_2000_J.Neurosci_20_5989 The Ets transcription factor GABP is required for postsynaptic differentiation in vivo
Daly_2000_Nat.Prod.Rep_17_131 Alkaloids from frog skin: the discovery of epibatidine and the potential for developing novel non-opioid analgesics
Lloyd_2000_J.Pharmacol.Exp.Ther_292_461 Neuronal nicotinic acetylcholine receptors as novel drug targets
Sheppard_2000_Int.J.Oncol_16_513 Activation of voltage-operated Ca2+-channels in human small cell lung carcinoma by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
Bailey_2000_Proc.Natl.Acad.Sci.U.S.A_97_11581 A novel function for serotonin-mediated short-term facilitation in aplysia: conversion of a transient, cell-wide homosynaptic hebbian plasticity into a persistent, protein synthesis-independent synapse-specific enhancement
Huxley_2000_Philos.Trans.R.Soc.Lond.B.Biol.Sci_355_539 Past, present and future experiments on muscle
Kandel_2000_Brain.Res.Brain.Res.Rev_32_3 Michael V.L. Bennett and the cellular study of neural systems at Albert Einstein and Woods Hole
Kauderer_2000_Proc.Natl.Acad.Sci.U.S.A_97_13342 Capture of a protein synthesis-dependent component of long-term depression
Martin_2000_Curr.Opin.Neurobiol_10_587 Local protein synthesis and its role in synapse-specific plasticity
Nguyen_2000_Learn.Mem_7_170 Strain-dependent differences in LTP and hippocampus-dependent memory in inbred mice
Skehel_2000_Proc.Natl.Acad.Sci.U.S.A_97_1101 Mouse VAP33 is associated with the endoplasmic reticulum and microtubules
Levandoski_2000_J.Neurochem_74_1279 Recombinant expression of alpha-bungarotoxin in Pichia pastoris facilitates identification of mutant toxins engineered to recognize neuronal nicotinic acetylcholine receptors
Nayak_2000_Neuropharmacol_39_2681 Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals
Sweileh_2000_Brain.Res.Mol.Brain.Res_75_293 Multistep expression and assembly of neuronal nicotinic receptors is both host-cell- and receptor-subtype-dependent
Van Renterghe_2000_Eur.J.Neurosci_12_3953 alpha-latrotoxin forms calcium-permeable membrane pores via interactions with latrophilin or neurexin
Espanol_2000_Pharmacol.Res_42_489 Participation of nitric oxide synthase and cyclo-oxygenase in the signal transduction pathway of ileal muscarinic acetylcholine receptors
Leiros_2000_J.Auton.Nerv.Syst_79_99 Differential activation of nitric oxide synthase through muscarinic acetylcholine receptors in rat salivary glands
Schultheiss_2000_Ann.N.Y.Acad.Sci_915_260 Carbachol-induced Ca2+ entry into rat colonic epithelium
Carlier_2000_Angew.Chem.Int.Ed.Engl_39_1775 Dimerization of an Inactive Fragment of Huperzine A Produces a Drug with Twice the Potency of the Natural Product
Kiderlen_2000_Arch.Toxicol_74_27 The phosphoryl oxime-destroying activity of human plasma
Israel_2000_Trends.Neurosci_23_47 Ladislav Tauc (1926-1999)
Liu_2000_J.Biol.Chem_275_41364 Interaction of MyoD family proteins with enhancers of acetylcholine receptor subunit genes in vivo
Weston_2000_J.Cell.Biol_150_205 Agrin-induced acetylcholine receptor clustering is mediated by the small guanosine triphosphatases Rac and Cdc42
Weston_2000_Exp.Cell.Res_260_374 Laminin-1 activates Cdc42 in the mechanism of laminin-1-mediated neurite outgrowth
Manco_2000_Arch.Biochem.Biophys_373_182 Cloning, overexpression, and properties of a new thermophilic and thermostable esterase with sequence similarity to hormone-sensitive lipase subfamily from the archaeon Archaeoglobus fulgidus
Haux_2000_Chem.Res.Toxicol_13_646 Phosphobutyrylcholinesterase: phosphorylation of the esteratic site of butyrylcholinesterase by ethephon [(2-chloroethyl)phosphonic acid] dianion
Tomizawa_2000_Toxicol.Appl.Pharmacol_169_114 Imidacloprid, thiacloprid, and their imine derivatives up-regulate the alpha 4 beta 2 nicotinic acetylcholine receptor in M10 cells
Tomizawa_2000_J.Agric.Food.Chem_48_6016 Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors
Zhang_2000_J.Neurochem_75_1294 Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site
Martinez_2000_Biochemistry_39_6979 Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time-resolved fluorescence spectroscopy
McGaughy_2000_Behav.Brain.Res_115_251 The role of cortical cholinergic afferent projections in cognition: impact of new selective immunotoxins
Passetti_2000_Eur.J.Neurosci_12_3051 Increased acetylcholine release in the rat medial prefrontal cortex during performance of a visual attentional task
Dobransky_2000_Biochem.J_349_141 Expression, purification and characterization of recombinant human choline acetyltransferase: phosphorylation of the enzyme regulates catalytic activity
Krol_2000_J.Comp.Neurol_427_54 Absence of p75(NTR) expression reduces nerve growth factor immunolocalization in cholinergic septal neurons
Elleder_2000_Virchows.Arch_436_82 Testis - a novel storage site in human cholesteryl ester storage disease. Autopsy report of an adult case with a long-standing subclinical course complicated by accelerated atherosclerosis and liver carcinoma
Krivit_2000_Bone.Marrow.Transplant_26_567 Wolman disease successfully treated by bone marrow transplantation
Aramakis_2000_J.Neurosci_20_6106 A critical period for nicotine-induced disruption of synaptic development in rat auditory cortex
Rusted_2000_Behav.Pharmacol_11_621 Moving out of the laboratory: does nicotine improve everyday attention?
Coulson_2000_Neurochem.Int_36_175 What the evolution of the amyloid protein precursor supergene family tells us about its function
Morley_2000_Hear.Res_147_104 Cholinergic receptors: dual roles in transduction and plasticity
Perrier_2000_J.Neurophysiol_83_3201 Cooperation of muscle and cutaneous afferents in the feedback of contraction to peroneal motoneurons
Perrier_2000_J.Neurophysiol_83_3209 Effects on peroneal motoneurons of cutaneous afferents activated by mechanical or electrical stimulations
Brocca_2000_Protein.Sci_9_985 Mutants provide evidence of the importance of glycosydic chains in the activation of lipase 1 from Candida rugosa
Dalmau_2000_Enzyme.Microb.Technol_26_657 Effect of different carbon sources on lipase production by Candida rugosa
Manetti_2000_Biochim.Biophys.Acta_1543_146 Design and realization of a tailor-made enzyme to modify the molecular recognition of 2-arylpropionic esters by Candida rugosa lipase
Armengaud_2000_Brain.Res_859_390 Functional cytochrome oxidase histochemistry in the honeybee brain
Berman_2000_J.Neurosci_20_7017 The role of identified neurotransmitter systems in the response of insular cortex to unfamiliar taste: activation of ERK1-2 and formation of a memory trace
Dudai_2000_Nature_406_686 Neurobiology. The shaky trace
Barbier_2000_Int.Microbiol_3_117 Esterases in marine dinoflagellates and resistance to the organophosphate insecticide parathion
Beisson_2000_Biochem.Soc.Trans_28_773 Assaying Arabidopsis lipase activity
Bray_2000_Protein.Eng_13_153 The CATH Dictionary of Homologous Superfamilies (DHS): a consensus approach for identifying distant structural homologues
Brody_2000_J.Cell.Biol_150_F83 Drosophila melanogaster G protein-coupled receptors
Buznikov_2000_Neurosci.Behav.Physiol_30_53 Cholinoreceptors of early (preneural) sea urchin embryos
Chahinian_2000_Biosci.Biotechnol.Biochem_64_215 Production of extracellular lipases by Penicillium cyclopium purification and characterization of a partial acylglycerol lipase
Chen_2000_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_127_97 Muscle regulatory factor gene: zebrafish (Danio rerio) myogenin cDNA
Hiol_2000_Enzyme.Microb.Technol_26_421 Purification and characterization of an extracellular lipase from a thermophilic Rhizopus oryzae strain isolated from palm fruit
Kumar_2000_J.Org.Chem_65_7800 Poly(3-hydroxybutyrate)-depolymerase from Pseudomonas lemoignei: catalysis of esterifications in organic media
Lin_2000_Proc.Natl.Acad.Sci.U.S.A_97_1299 Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice
Lowe_2000_Biochimie_82_997 Properties and function of pancreatic lipase related protein 2
Nakagawa_2000_Bioorg.Med.Chem_8_2663 3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues
Paterson_2000_Prog.Neurobiol_61_75 Neuronal nicotinic receptors in the human brain
Pearl_2000_Biochem.Soc.Trans_28_269 Using the CATH domain database to assign structures and functions to the genome sequences
Sanes_2000_Annu.Rev.Neurosci_23_393 Plasticity and primary motor cortex
Shen_2000_Biochemistry_39_2392 Hormone-sensitive lipase functions as an oligomer
Thornton_2000_Nat.Struct.Biol_7 Suppl_991 From structure to function: approaches and limitations
Waggoner_2000_J.Neurosci_20_8802 Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance
Yang_2000_Pediatr.Res_47_184 Discoordinate expression of pancreatic lipase and two related proteins in the human fetal pancreas
Yoshiyama_2000_Genetica_108_81 Survey of mariner-like elements in the housefly, Musca domestica
Zhao_2000_Development_127_1253 A retrograde signal is involved in activity-dependent remodeling at a C. elegans neuromuscular junction
Agarwala_2000_Biochem.Biophys.Res.Commun_272_641 Phosphorylation of RTP, an ER stress-responsive cytoplasmic protein
Ahmadi_2000_Biochem.Biophys.Res.Commun_269_676 GSTM1 and mEPHX polymorphisms in Parkinson's disease and age of onset
Andberg_2000_Biochem.J_345 Pt 3_621 Leukotriene A4 hydrolase: a critical role of glutamic acid-296 for the binding of bestatin
Arahira_2000_Eur.J.Biochem_267_2649 Purification, molecular cloning and ethylene-inducible expression of a soluble-type epoxide hydrolase from soybean (Glycine max [L.] Merr.)
Argiriadi_2000_J.Biol.Chem_275_15265 Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation
Armstrong_2000_Drug.Metab.Rev_32_327 New structural and chemical insight into the catalytic mechanism of epoxide hydrolases
Boogaard_2000_Xenobiotica_30_485 Metabolic inactivation of five glycidyl ethers in lung and liver of humans, rats and mice in vitro
Boyle_2000_Chem.Biol.Interact_125_209 Gender-specific metabolism of benz[a]anthracene in hepatic microsomes from Long-Evans and Hooded Lister rats
Burkey_2000_Mutat.Res_453_25 Cytotoxicity and genotoxicity of methyleugenol and related congeners-- a mechanism of activation for methyleugenol
Cantallops_2000_Curr.Biol_10_R620 Synapse formation: if it looks like a duck and quacks like a duck
Carlson_2000_J.Toxicol.Environ.Health.A_61_709 Metabolism of styrene oxide to styrene glycol in enriched mouse clara-cell preparations
Chiappe_2000_Chem.Res.Toxicol_13_831 Stereochemical course of the biotransformation of isoprene monoepoxides and of the corresponding diols with liver microsomes from control and induced rats
Cho_2000_Toxicology_146_111 Enhanced expression of rat hepatic microsomal epoxide hydrolase by methylthiazole in conjunction with liver injury
Choi_2000_Appl.Microbiol.Biotechnol_54_641 Continuous production of enantiopure 1,2-epoxyhexane by yeast epoxide hydrolase in a two-phase membrane bioreactor
Clapper_2000_Curr.Oncol.Rep_2_251 Genetic polymorphism and cancer risk
Csanady_2000_Toxicol.Appl.Pharmacol_165_1 A physiological toxicokinetic model for exogenous and endogenous ethylene and ethylene oxide in rat, mouse, and human: formation of 2-hydroxyethyl adducts with hemoglobin and DNA
De Berardinis_2000_Mol.Pharmacol_58_542 Human microsomal epoxide hydrolase is the target of germander-induced autoantibodies on the surface of human hepatocytes
Draper_2000_Arch.Biochem.Biophys_376_199 Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase
Edqvist_2000_Biochem.Soc.Trans_28_855 Characterization of a Euphorbia lagascae epoxide hydrolase gene that is induced early during germination
Fanucchi_2000_Toxicol.Appl.Pharmacol_168_253 Development of phase II xenobiotic metabolizing enzymes in differentiating murine clara cells
Getova_2000_Folia.Med.(Plovdiv)_42_5 Effects of the anticholinesterase drug tacrine on the development of PTZ kindling and on learning and memory processes in mice
Glauser_2000_Epilepsia_41 Suppl 8_S16 Idiosyncratic reactions: new methods of identifying high-risk patients
Grove_2000_Toxicol.Appl.Pharmacol_162_34 Differential protection by rat UDP-glucuronosyltransferase 1A7 against Benzo[a]pyrene-3,6-quinone- versus Benzo[a]pyrene-induced cytotoxic effects in human lymphoblastoid cells
Gu_2000_Toxicol.Appl.Pharmacol_165_158 Expression of biotransformation enzymes in human fetal olfactory mucosa: potential roles in developmental toxicity
Gura_2000_Science_288_1718 Neurobiology. Trigger found for synapse formation
Haeggstrom_2000_Am.J.Respir.Crit.Care.Med_161_S25 Structure, function, and regulation of leukotriene A4 hydrolase
Haeggstrom_2000_Ernst.Schering.Res.Found.Workshop__85 Leukotriene-A4 hydrolase: probing the active sites and catalytic mechanisms by site-directed mutagenesis
Hattori_2000_Endocrinology_141_3353 Epoxide hydrolase affects estrogen production in the human ovary
Heinzmann_2000_Clin.Exp.Allergy_30_1555 Studies on linkage and association of atopy with the chromosomal region 12q13-24
Hengstler_2000_Drug.Metab.Rev_32_81 Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction
Holmquist_2000_Curr.Protein.Pept.Sci_1_209 Alpha\/Beta-hydrolase fold enzymes: structures, functions and mechanisms
Jourenkova-Mironova_2000_Cancer.Res_60_534 High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers
Kessler_2000_Cancer.Res_60_1403 Identification of the putative brain tumor antigen BF7\/GE2 as the (de)toxifying enzyme microsomal epoxide hydrolase
Kim_2000_Liver_20_319 Inhibition of lipopolysaccharide-induced I-kappaB degradation and tumor necrosis factor-alpha expression by dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB): minor role in hepatic detoxifying enzyme expression
Kimura_2000_Am.J.Ophthalmol_130_769 Genetic association of manganese superoxide dismutase with exudative age-related macular degeneration
Kohn_2000_Environ.Health.Perspect_108 Suppl 5_911 The privileged access model of 1,3-butadiene disposition
Krovat_2000_Toxicol.Sci_55_352 Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells
Lakritz_2000_Am.J.Vet.Res_61_152 Hepatic and pulmonary enzyme activities in horses
Lamb_2000_Drug.Metab.Dispos_28_1018 Early events in the induction of rat hepatic UDP-glucuronosyltransferases, glutathione S-transferase, and microsomal epoxide hydrolase by 1,7-phenanthroline: comparison with oltipraz, tert-butyl-4-hydroxyanisole, and tert-butylhydroquinone
Lee_2000_Res.Commun.Mol.Pathol.Pharmacol_108_155 Enhanced expression of microsomal epoxide hydrolase and glutathione S-transferase by imidazole correlates with the radioprotective effect
Lin_2000_Br.J.Cancer_82_852 Association of CYP1A1 and microsomal epoxide hydrolase polymorphisms with lung squamous cell carcinoma
Linderman_2000_Insect.Biochem.Mol.Biol_30_767 Inhibition of insect juvenile hormone epoxide hydrolase: asymmetric synthesis and assay of glycidol-ester and epoxy-ester inhibitors of trichoplusia ni epoxide hydrolase
London_2000_Lung.Cancer_28_147 Lung cancer risk in relation to genetic polymorphisms of microsomal epoxide hydrolase among African-Americans and Caucasians in Los Angeles County
Montero_2000_Exp.Nephrol_8_258 Reciprocal regulation of LTA(4) hydrolase expression in human monocytes by gamma-interferon and interleukins 4 and 13: potential relevance to leukotriene regulation in glomerular disease
Moussou_2000_Enzyme.Microb.Technol_26_414 Clues for the existence of two different epoxide hydrolase activities in the fungus Beauveria bassiana
Mushiroda_2000_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_126_225 The house musk shrew (Suncus murinus): a unique animal with extremely low level of expression of mRNAs for CYP3A and flavin-containing monooxygenase
Nimmrich_2000_Cancer.Lett_160_37 Seven genes that are differentially transcribed in colorectal tumor cell lines
Oesch_2000_Toxicol.Pathol_28_382 Metabolic detoxification: implications for thresholds
Ohba_2000_Jpn.J.Ophthalmol_44_320 Introduction to genetics in ophthalmology, value of family studies
Omiecinski_2000_Toxicol.Lett_112-113_365 Epoxide hydrolase--polymorphism and role in toxicology
Patterson_2000_Cell.Death.Differ_7_137 Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition
Penning_2000_J.Med.Chem_43_721 Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase
Pinot_2000_Biochem.Soc.Trans_28_867 omega-Hydroxylation of epoxy- and hydroxy-fatty acids by CYP94A1: possible involvement in plant defence
Pluth_2000_Pharmacogenet_10_311 The relationship between genotype and chromosome aberration frequencies in a normal adult population
Pluth_2000_Mutat.Res_465_101 Role of maternal exposures and newborn genotypes on newborn chromosome aberration frequencies
Pudota_2000_Proc.Natl.Acad.Sci.U.S.A_97_13033 Identification of the vitamin K-dependent carboxylase active site: Cys-99 and Cys-450 are required for both epoxidation and carboxylation
Rao_2000_Nat.Neurosci_3_747 Neuroligation: building synapses around the neurexin-neuroligin link
Rink_2000_Biochemistry_39_5600 Tyrosine residues serve as proton donor in the catalytic mechanism of epoxide hydrolase from Agrobacterium radiobacter
Rump_2000_Neurotox.Res_2_17 Effects of imidazenil, a new benzodiazepine receptor partial agonist, in the treatment of convulsions in organophosphate intoxications
Sarmanova_2000_Pharmacogenet_10_781 Genetic polymorphisms of biotransformation enzymes: allele frequencies in the population of the Czech Republic
Schilter_2000_J.Pharmacol.Exp.Ther_294_916 Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers
Sinal_2000_J.Biol.Chem_275_40504 Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation
Takeyabu_2000_Eur.Respir.J_15_891 Gene polymorphism for microsomal epoxide hydrolase and susceptibility to emphysema in a Japanese population
Talalay_2000_Biofactors_12_5 Chemoprotection against cancer by induction of phase 2 enzymes
Taura_2000_Biochem.Biophys.Res.Commun_273_1048 Interaction between cytochrome P450 and other drug-metabolizing enzymes: evidence for an association of CYP1A1 with microsomal epoxide hydrolase and UDP-glucuronosyltransferase
Thum_2000_Lancet_355_979 Gene expression in distinct regions of the heart
Li_2000_Biochim.Biophys.Acta_1481_237 Hyperactivity and interactions of a chimeric myristoryl-ACP thioesterase from the lux system of luminescent bacteria
McCarroll_2000_Nature_407_961 Insecticides and mosquito-borne disease
Boorman_2000_J.Physiol_529 Pt 3_565 Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes
De Gois_2000_J.Biol.Chem_275_36683 Is RE1\/NRSE a common cis-regulatory sequence for ChAT and VAChT genes?
Hernandez_2000_J.Pharmacol.Exp.Ther_293_962 Dextromethorphan and its metabolite dextrorphan block alpha3beta4 neuronal nicotinic receptors
Albuquerque_2000_Behav.Brain.Res_113_131 Neuronal nicotinic receptors in synaptic functions in humans and rats: physiological and clinical relevance
Alkondon_2000_Neuropharmacol_39_2726 Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus
Alkondon_2000_J.Neurosci_20_66 Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks
Almeida_2000_Neuropharmacol_39_2740 The opioid antagonist naltrexone inhibits activity and alters expression of alpha7 and alpha4beta2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs
Mike_2000_Brain.Res_873_112 Ca(2+)-sensitive inhibition by Pb(2+) of alpha7-containing nicotinic acetylcholine receptors in hippocampal neurons
Duque_2000_J.Neurophysiol_84_1627 EEG correlation of the discharge properties of identified neurons in the basal forebrain
Zaborszky_2000_Behav.Brain.Res_115_143 Local synaptic connections of basal forebrain neurons
Hosli_2000_Neurochem.Int_36_301 Colocalization of neurotransmitter receptors on astrocytes in explant cultures of rat CNS
Hosli_2000_Int.J.Dev.Neurosci_18_101 Histochemical and electrophysiological evidence for estrogen receptors on cultured astrocytes: colocalization with cholinergic receptors
Pratt_2000_J.Biol.Chem_275_29441 Identification of sites of incorporation in the nicotinic acetylcholine receptor of a photoactivatible general anesthetic
Lluel_2000_Am.J.Physiol.Regul.Integr.Comp.Physiol_278_R964 Functional and morphological modifications of the urinary bladder in aging female rats
Buschges_2000_J.Neurophysiol_84_2758 Roles of high-voltage-activated calcium channel subtypes in a vertebrate spinal locomotor network
Elbaum_2000_Biochem.Biophys.Res.Commun_267_733 Implication of novel biochemical property of beta-amyloid
Gray_2000_Cell.Transplant_9_153 Conditionally immortalized, multipotential and multifunctional neural stem cell lines as an approach to clinical transplantation
Grigoryan_2000_Restor.Neurol.Neurosci_17_1 Conditionally immortal neuroepithelial stem cell grafts restore spatial learning in rats with lesions at the source of cholinergic forebrain projections cholinergic forebrain projections Conditionally immortal neuroepithelial stem cell grafts restore spatial leaming in rats with lesions at the source of cholinergic forebrain projections
Holm_2000_Annu.Rev.Nutr_20_365 Molecular mechanisms regulating hormone-sensitive lipase and lipolysis
Li_2000_Mol.Med_6_1008 Potent induction of apoptosis by beta-lapachone in human multiple myeloma cell lines and patient cells
Kreft_2000_Pflugers.Arch_439_r066 Nonradioactive northern blotting for the determination of acetylcholinesterase mRNA. Comparison to the radioactive technique
Chen_2000_Nature_408_936 Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms
Frenkel_2000_Proc.Natl.Acad.Sci.U.S.A_97_11455 Immunization against Alzheimer's beta -amyloid plaques via EFRH phage administration
Frenkel_2000_J.Neuroimmunol_106_23 Modulation of Alzheimer's beta-amyloid neurotoxicity by site-directed single-chain antibody
Schiller_2000_Nature_404_285 NMDA spikes in basal dendrites of cortical pyramidal neurons
Solomon_2000_Drugs.Today.(Barc)_36_655 Vaccination for the prevention and treatment of Alzheimer's disease
Riley_2000_J.Immunol_165_4870 Graded deletion and virus-induced activation of autoreactive CD4+ T cells
Ikeda_2000_Clin.Sci.(Lond)_99_569 A compound heterozygote for a novel missense mutation (G105R) in exon 3 and a missense mutation (D204E) in exon 5 of the lipoprotein lipase gene in a Japanese infant with hyperchylomicronaemia
Holzl_2000_J.Lipid.Res_41_734 Two novel mutations in the lipoprotein lipase gene in a family with marked hypertriglyceridemia in heterozygous carriers. Potential interaction with the polymorphic marker D1S104 on chromosome 1q21-q23
Mori_2000_Clin.Biochem_33_323 Improved method for direct DNA sequencing of the human lipoprotein lipase gene using an auto DNA sequencer
Takagi_2000_Biochim.Biophys.Acta_1502_433 A newly identified lipoprotein lipase (LPL) gene mutation (F270L) in a Japanese patient with familial LPL deficiency
Salonen_2000_Hum.Mutat_15_273 Detection of eight novel palmitoyl protein thioesterase (PPT) mutations underlying infantile neuronal ceroid lipofuscinosis (INCL\;CLN1)
Waliany_2000_Hum.Mutat_15_206 Identification of three novel mutations of the palmitoyl-protein thioesterase-1 (PPT1) gene in children with neuronal ceroid-lipofuscinosis
Garcia_2000_Biomarkers_5_274 Characterization of cholinesterase from guppy (Poecilia reticulata) muscle and its in vitro inhibition by environmental contaminants
Yoshida_2000_J.Atheroscler.Thromb_7_45 A Japanese patient with lipoprotein lipase deficiency homozygous for the Gly188Glu mutation prevalent worldwide
Moya_2000_Eur.J.Endocrinol_143_789 Genomic organization of the 5' region of the human thyroglobulin gene
Xu_2000_Am.J.Kidney.Dis_36_42 Platelet-activating factor acetylhydrolase gene mutation in Japanese children with Escherichia coli O157-associated hemolytic uremic syndrome
Pignol_2000_J.Biol.Chem_275_4220 Critical role of micelles in pancreatic lipase activation revealed by small angle neutron scattering
Shapira_2000_Hum.Mol.Genet_9_1273 A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases
Stocks_2000_Atherosclerosis_149_219 A common lecithin: cholesterol acyltransferase gene variant (Ser208-->Thr)
Agmo_2000_IDrugs_3_743 International Behavioral Neuroscience Society - ninth annual meeting
Sepp_2000_Glia_30_122 Developmental dynamics of peripheral glia in Drosophila melanogaster
Takamiya_2000_Trends.Plant.Sci_5_426 Degradation pathway(s) of chlorophyll: what has gene cloning revealed?
Ishigaki_2000_J.Biosci.Bioeng_90_400 Enzymatic degradation of cellulose acetate plastic by Novel degrading bacterium Bacillus sp. S2055
Kashima_2000_J.Biosci.Bioeng_89_81 Role of intracellular esterases in the production of esters by Acetobacter pasteurianus
Kato_2000_J.Biosci.Bioeng_90_332 Efficient preparation of optically active ketoprofen by Mucor javanicus lipase immobilized on an inorganic support
Kobayashi_2000_J.Biosci.Bioeng_90_422 Accumulation of a recombinant Aspergillus oryzae lipase artificially localized on the Bacillus subtilis cell surface
Mine_2000_J.Biosci.Bioeng_90_631 Preparation of detergent-lipase complexes utilizing water-soluble amphiphiles in single aqueous phase and catalysis of transesterifications in homogeneous organic solvents
Nagao_2000_J.Biosci.Bioeng_89_446 Amino acid residues contributing to stabilization of Fusarium heterosporum lipase
Nakajima_2000_J.Biosci.Bioeng_90_347 Regioselective acylation of flavonoid glucoside with aromatic acid by an enzymatic reaction system from cultured cells of Ipomoea batatas
Nishimura_2000_J.Biosci.Bioeng_90_564 Inhibitory effects of carbohydrates on cholesterol esterase biosynthesis in Streptomyces lavendulae H646-SY2
Ueda_2000_J.Biosci.Bioeng_90_125 Cell surface engineering of yeast: construction of arming yeast with biocatalyst
Yasuda_2000_J.Biosci.Bioeng_90_681 Effect of additives on transesterification activity of Rhizopus chinensis lipase
Aizawa_2000_Respiration_67_652 Histamine-induced increase in isometric tension of smooth muscle is mediated by local vagus nerve in human bronchus
Akiyama_2000_Cardiovasc.Res_46_531 Adrenergic inhibition of endogenous acetylcholine release on postganglionic cardiac vagal nerve terminals
Bailey_2000_Can.J.Clin.Pharmacol_7_198 Antidote availability in Quebec hospital pharmacies: impact of N-acetylcysteine and naloxone consumption
Bercik_2000_Gastroenterology_119_386 Quantitative analysis of intestinal motor patterns: spatiotemporal organization of nonneural pacemaker sites in the rat ileum
Boccia_2000_Neurobiol.Learn.Mem_74_217 Involvement of central cholinergic mechanisms in the effects of oxytocin and an oxytocin receptor antagonist on retention performance in mice
Braida_2000_Pharmacol.Res_42_495 Eptastigmine restores the aged rat's normal cortical spectral power pattern
Buttarelli_2000_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_125_225 Acetylcholine\/dopamine interaction in planaria
Byth_2000_Perception_29_461 Cholinergic agents and the McCollough effect
Castanon_2000_An.Esp.Pediatr_53_53 [Datura stramonium poisoning]
Chen_2000_Drug.Dev.Ind.Pharm_26_1007 Anaerobic stability of aqueous physostigmine solution
Dart_2000_Ann.Emerg.Med_36_126 Combined evidence-based literature analysis and consensus guidelines for stocking of emergency antidotes in the United States
Dean_2000_Mayo.Clin.Proc_75_872 Physostigmine treatment of gamma-hydroxybutyric acid overdose: appropriate or inappropriate use of a reversal agent?
Degroot_2000_Learn.Mem_7_293 Increasing acetylcholine levels in the hippocampus or entorhinal cortex reverses the impairing effects of septal GABA receptor activation on spontaneous alternation
Ding_2000_J.Neurochem_74_1514 Dopamine receptor-mediated regulation of striatal cholinergic activity: positron emission tomography studies with norchloro[18F]fluoroepibatidine
Engberg_2000_Naunyn.Schmiedebergs.Arch.Pharmacol_362_41 Nicotine inhibits firing activity of dorsal raphe 5-HT neurones in vivo
Futagawa_2000_Toxicol.Appl.Pharmacol_165_27 The role of cholinergic and noncholinergic mechanisms in the cardiorespiratory failure produced by N-methylcarbamate cholinesterase inhibitors in rabbits
Ghelardini_2000_Br.J.Pharmacol_129_1633 Loss of muscarinic antinociception by antisense inhibition of M(1) receptors
Ghelardini_2000_Fitoterapia_71 Suppl 1_S124 Pro-cognitive activity induced in the rat by low doses of R-(+)-hyoscyamine
Giorgetti_2000_Eur.J.Neurosci_12_1941 Local GABAergic modulation of acetylcholine release from the cortex of freely moving rats
Groszek_2000_Przegl.Lek_57_577 [Self-poisoning with Datura stramonium]
Hala_2000_Immunobiology_201_598 Expression of nonspecific esterase (NSE) by thyroid follicular epithelium as a marker for the target organ susceptibility to immune system attack
Heindl_2000_Dtsch.Med.Wochenschr_125_1361 [Etiology of initially unexplained confusion of excitability in deadly nightshade poisoning with suicidal intent. Symptoms, differential diagnosis, toxicology and physostigmine therapy of anticholinergic syndrome]
Holmes_2000_N.Z.Med.J_113_129 Fantasy-drug of abuse
Hurh_2000_Biopharm.Drug.Dispos_21_331 Effects of physostigmine on the pharmacokinetics of intravenous parathion in rats
Iturriaga_2000_Brain.Res_868_380 Lack of correlation between cholinergic-induced changes in chemosensory activity and dopamine release from the cat carotid body in vitro
Kahl_2000_Neurosci.Lett_285_17 Influence of muscarinic ligands on the amplitudes of the evoked surface potential's late components in the optic tectum of the urodele Plethodon jordani
Kamei_2000_Brain.Res_887_183 Mechanism responsible for epileptogenic activity by first-generation H1-antagonists in rats
Kaneko_2000_Methods.Find.Exp.Clin.Pharmacol_22_163 The mechanism responsible for the drowsiness caused by first generation H1 antagonists on the EEG pattern
Karan_2000_Methods.Find.Exp.Clin.Pharmacol_22_169 Effect of muscarinic receptor agonists on animal models of psychosis
Kawahara_2000_Org.Lett_2_675 An efficient synthesis of optically active physostigmine from tryptophan via alkylative cyclization
Kerr_2000_Clin.Exp.Pharmacol.Physiol_27_934 Effects of tachykinin receptor agonists and antagonists on the guinea-pig isolated oesophagus
Kubo_2000_Brain.Res.Bull_53_275 Cholinergic inputs to rostral ventrolateral medulla pressor neurons from hypothalamus
Kuhl_2000_Ann.Neurol_48_391 Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex
Levy_2000_Neuropsychology_14_288 Acetylcholine affects the spatial scale of attention: evidence from Alzheimer's disease
Lockridge_2000_Neurotoxicol_21_113 Pesticides and susceptible populations: people with butyrylcholinesterase genetic variants may be at risk
Lopes_2000_Bioorg.Med.Chem_8_707 Acyloxymethyl as a drug protecting group. Part 6: N-acyloxymethyl- and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group
Mae_2000_Xenobiotica_30_565 Identification of enzymes responsible for rifalazil metabolism in human liver microsomes
McGrath_2000_Cochrane.Database.Syst.Rev__CD000207 Cholinergic medication for neuroleptic-induced tardive dyskinesia
Meuret_2000_Anesthesiology_93_708 Physostigmine reverses propofol-induced unconsciousness and attenuation of the auditory steady state response and bispectral index in human volunteers
Mirza_2000_Psychopharmacology.(Berl)_148_243 The role of nicotinic and muscarinic acetylcholine receptors in attention
Mishima_2000_Jpn.J.Pharmacol_84_163 The scopolamine-induced impairment of spatial cognition parallels the acetylcholine release in the ventral hippocampus in rats
Mullins_2000_Mayo.Clin.Proc_75_871 Physostigmine treatment of gamma-hydroxybutyric acid overdose: appropriate or inappropriate use of a reversal agent?
Nakagawa_2000_Org.Lett_2_953 A concise synthesis of physostigmine from skatole and activated aziridine via alkylative cyclization
Nakagawasai_2000_Brain.Res.Bull_52_189 Immunohistochemical estimation of brain choline acetyltransferase and somatostatin related to the impairment of avoidance learning induced by thiamine deficiency
Pachaly_2000_Pharmazie_55_777 [Angelicastigmin, a new eserine alkaloid from Angelica polymorpha]
Parisi_2000_Pediatr.Neurol_23_185 A female with central anticholinergic syndrome responsive to neostigmine
Peruzzi_2000_Ann.N.Y.Acad.Sci_903_394 Differentiated cerebrovascular effects of physostigmine and tacrine in cortical areas deafferented from the nucleus basalis magnocellularis suggest involvement of basalocortical projections to microvessels
Podol'skii_2000_Zh.Vyssh.Nerv.Deiat.Im.I.P.Pavlova_50_982 [Long-term changes in EEG spectra of the hippocampus and neocortex during pharmacological action on the cholinergic system]
Popke_2000_Pharmacol.Biochem.Behav_67_377 Comparison of drug effects on the performance of two timing tasks in rats
Powell_2000_Anesth.Analg_90_1423 Ondansetron given before induction of anesthesia reduces shivering after general anesthesia
Pruvost_2000_J.Mass.Spectrom_35_625 Fully automated determination of eserine N-oxide in human plasma using on-line solid-phase extraction with liquid chromatography coupled with electrospray ionization tandem mass spectrometry
Rowland_2000_J.Control.Release_68_157 The electrostability and electrically assisted delivery of an organophosphate pretreatment (physostigmine) across human skin in vitro
Sanz_2000_Brain.Res_854_42 Role of calcium on the modulation of spontaneous acetylcholine efflux by the D2 dopamine receptor subtype in rat striatal synaptosomes
Sarkar_2000_Behav.Brain.Res_109_187 Effects of serotoninergic drugs on tremor induced by physostigmine in rats
Sienkiewicz-Jarosz_2000_J.Neural.Transm.(Vienna)_107_1403 The effects of physostigmine and cholinergic receptor ligands on novelty-induced neophobia
Southgate_2000_J.R.Soc.Promot.Health_120_127 Lessons to be learned: a case study approach. Unseasonal severe poisoning of two adults by deadly nightside (Atropa belladonna)
Tanaka_2000_Pharmacol.Biochem.Behav_66_827 Recovery of diminished mealtime-associated anticipatory behavior by aniracetam in aged rats
Thatte_2000_IDrugs_3_1222 Phenserine (Axonyx\/NIH)
Thor_2000_Brain.Res_870_126 Central muscarinic inhibition of lower urinary tract nociception
Napoli_2000_Minerva.Gastroenterol.Dietol_46_73 Evolution of acute pancreatitis in diabetes mellitus
Rafi_2000_Pak.J.Pharm.Sci_13_13 Correlation between toxic natures of pyrethroid and behavioral response of desert locusts
Taten_2000_Proc.(Bayl.Univ.Med.Cent)_13_419 Epigastric pain with elevated serum calcium, lipase, and amylase
Yates_2000_Mayo.Clin.Proc_75_401 Physostigmine in the treatment of gamma-hydroxybutyric acid overdose
Yokotani_2000_Eur.J.Pharmacol_392_23 Histamine H(3) receptor-mediated inhibition of endogenous acetylcholine release from the isolated, vascularly perfused rat stomach
Brophy_2000_Pharmacogenet_10_453 Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype
Burruel_2000_Toxicol.Appl.Pharmacol_165_148 Paternal effects from methamidophos administration in mice
Cameron_2000_Spine.(Phila.Pa.1976)_25_1917 A prospective study of serum pseudocholinesterase levels in patients with chronic spinal pain: a preliminary study
Clair_2000_Eur.J.Pharm.Sci_9_259 Stability study of a new antidote drug combination (Atropine-HI-6-Prodiazepam) for treatment of organophosphate poisoning
Fitzpatrick_2000_J.Am.Coll.Cardiol_36_179 Tilt methodology in reflex syncope: emerging evidence
Galisteo_2000_J.Pharmacol.Exp.Ther_294_160 Hepatotoxicity of tacrine: occurrence of membrane fluidity alterations without involvement of lipid peroxidation
Gou_2000_Anal.Chem_72_2774 In-tube solid-phase microextraction coupled to capillary LC for carbamate analysis in water samples
Kittl_2000_Clin.Chem.Lab.Med_38_205 Serum protein 90K\/Mac-2BP is an independent predictor of disease severity during hepatitis C virus infection
Namekata_2000_Surg.Today_30_403 Significant changes in the serum levels of IL-6, h-HGF, and type IV collagen 7S during the perioperative period of a hepatectomy: relevance to SIRS
Novitskii_2000_Dokl.Biochem_371_57 Acetylcholine content and the localization of acetylcholine esterase activity in different tissues of magnetic-orientation types of radish
Petrovic_2000_Pharmazie_55_454 The treatment of delayed polyneuropathy induced by diisopropylfluorophosphate in hens
Sailer_2000_Anat.Embryol.(Berl)_201_27 Induction of cellular contractions in the human melanoma cell line SK-mel 28 after muscarinic cholinergic stimulation
Stoppe_2000_Internist.(Berl)_41_538 [Chief psychiatric problems in old age]
Tariot_2000_Neurology_54_2269 A 5-month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA-10 Study Group
Nordberg_2000_Neurotox.Res_2_157 Neuroprotection in Alzheimer's disease - new strategies for treatment
Pihlajamaki_2000_Arterioscler.Thromb.Vasc.Biol_20_1789 G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia
Buhler_2000_Chemistry_6_2564 A convenient synthesis of optically active 5,5-disubstituted 4-amino- and 4-hydroxy-2(5H)-furanones from (S)-ketone cyanohydrins
Effenberger_2000_Curr.Opin.Biotechnol_11_532 Hydroxynitrile lyases in stereoselective catalysis
Willeman_2000_Enzyme.Microb.Technol_27_423 Estimation of kinetic parameters by progress curve analysis for the synthesis of (R)-mandelonitrile by Prunus amygdalus hydroxynitrile lyase
Ambrus_2000_Food.Addit.Contam_17_519 Within and between field variability of residue data and sampling implications
Andersson_2000_Food.Addit.Contam_17_547 Comparison of pesticide residues in composite samples and in individual units: the Swedish approach to sampling
Ballard_2000_Ann.Neurol_48_868 Delusions associated with elevated muscarinic binding in dementia with Lewy bodies
Basova_2000_Zh.Evol.Biokhim.Fiziol_36_97 [Kinetic analysis of the 'substrate protective effect' for cholinesterases of various origin]
Bello-Ramirez_2000_Toxicology_149_63 A theoretical approach to the mechanism of biological oxidation of organophosphorus pesticides
Caldas_2000_Rev.Saude.Publica_34_529 [Assessment of the chronic risk for ingestion of pesticide residues in the Brazilian diet]
Carter_2000_Food.Addit.Contam_17_503 Investigations into the causes of residue variability on carrots in the UK
Cashman_2000_J.Pharmacol.Exp.Ther_293_952 Catalytic antibodies that hydrolyze (-)-cocaine obtained by a high-throughput procedure
Dallocchio_2000_J.Clin.Psychiatry_61_64 Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease
Diez_2000_Clin.Endocrinol.(Oxf)_53_587 Cholinergic modulation of growth hormone responses to growth hormone-releasing hormone in uraemic patients on peritoneal dialysis
Fureder_2000_Cancer.Genet.Cytogenet_121_133 Reciprocal translocation (3\;5)(q26\;q22) and possible BCHE gene involvement in an unusual myelogenous disorder with both myeloproliferative and dysplastic features
Gomez_2000_J.Neurosci.Res_62_134 Muscular dystrophy alters the processing of light acetylcholinesterase but not butyrylcholinesterase forms in liver of Lama2(dy) mice
Gray_2000_Risk.Anal_20_665 Risk\/risk trade-offs in pesticide regulation: an exploratory analysis of the public health effects of a ban on organophosphate and carbamate pesticides
Gultekin_2000_Arch.Toxicol_74_533 The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro)
Hatjian_2000_Mutat.Res_472_85 Cytogenetic response without changes in peripheral cholinesterase enzymes following exposure to a sheep dip containing diazinon in vivo and in vitro
He_2000_Neurotoxicol_21_829 Neurotoxic effects of insecticides--current and future research: a review
Hill_2000_Food.Addit.Contam_17_539 Residue variability and sampling--practical problems and consequences for residues monitoring
Horton_2000_Parasitol_121 Suppl_S147 An analysis of the safety of the single dose, two drug regimens used in programmes to eliminate lymphatic filariasis
Houston_2000_Parasitol_121 Suppl_S161 Salt fortified with diethylcarbamazine (DEC) as an effective intervention for lymphatic filariasis, with lessons learned from salt iodization programmes
Kato_2000_Microbiol.Immunol_44_719 Molecular cloning and partial characterization of rat procarboxypeptidase R and carboxypeptidase N
Khan_2000_Toxicol.Sci_57_112 Acute sarin exposure causes differential regulation of choline acetyltransferase, acetylcholinesterase, and acetylcholine receptors in the central nervous system of the rat
Kikuchi_2000_Ecotoxicol.Environ.Saf_47_239 Screening of organophosphate insecticide pollution in water by using Daphnia magna
Kwak_2000_Lancet_355_2222 Relation between cholinesterase inhibitor and Pisa syndrome
Lamprea_2000_Behav.Brain.Res_117_97 Dissociation of memory and anxiety in a repeated elevated plus maze paradigm: forebrain cholinergic mechanisms
Lee_2000_Am.J.Med.Genet_96_167 No association between butyrylcholinesterase K-variant and Alzheimer disease in Chinese
Lefferts_2000_Food.Addit.Contam_17_511 Pesticide residues variability and acute dietary risk assessment: a consumer perspective
Lenigk_2000_Biosens.Bioelectron_15_541 Enzyme biosensor for studying therapeutics of Alzheimer's disease
Lucinei_2000_Horm.Res_54_186 Insulin secretion and acetylcholinesterase activity in monosodium l-glutamate-induced obese mice
Mason_2000_Occup.Med.(Lond)_50_343 The recovery of plasma cholinesterase and erythrocyte acetylcholinesterase activity in workers after over-exposure to dichlorvos
Oliveira_2000_Cad.Saude.Publica_16 Suppl 2_105 [Focal and total residual insecticide spraying to control Triatoma brasiliensis and Triatoma pseudomaculata in Northeast Brazil]
Oliveira-Lima_2000_Cad.Saude.Publica_16 Suppl 2_75 [Peridomiciliary changes and implications for Triatoma brasiliensis control]
O'Rourke_2000_J.Expo.Anal.Environ.Epidemiol_10_672 Pesticide exposure and creatinine variation among young children
Raslavtseva_2000_Gig.Sanit__48 [Resistance of synanthropic insects to insecticides]
Reiner_2000_Pflugers.Arch_440_R118 Cholinesterase: substrate inhibition and substrate activation
Reiner_2000_Arh.Hig.Rada.Toksikol_51_13 Comparison of protocols for measuring activities of human blood cholinesterases by the Ellman method
Richards_2000_Mol.Pharmacol_58_577 Identification of acylpeptide hydrolase as a sensitive site for reaction with organophosphorus compounds and a potential target for cognitive enhancing drugs
Risinger_2000_Neurotoxicol.Teratol_22_667 Quantitative trait loci for acute behavioral sensitivity to paraoxon
Sanchez-Chavez_2000_IUBMB.Life_49_283 Effect of streptozotocin-induced diabetes on activities of cholinesterases in the rat retina
Sedlarova_2000_Ceska.Slov.Farm_49_306 [Local anesthetics: part 153. Relation between the chemical structure, physico-chemical properties and biological activity in a series of piperidinopropylesters of alkoxy-substituted phenylcarbamic acids]
Shih_2000_Arch.Toxicol_74_165 Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication
Sramek_2000_Expert.Opin.Investig.Drugs_9_2393 Review of the acetylcholinesterase inhibitor galanthamine
Suyatna_2000_Int.J.Clin.Pharmacol.Ther_38_339 Butyrylcholinesterase and C5+ variant in a Javanese ethnic group in Indonesia
Tecles_2000_Vet.J_160_242 Use of whole blood for spectrophotometric determination of cholinesterase activity in dogs
Tsukada_2000_Brain.Res_857_158 Age-related impairment of coupling mechanism between neuronal activation and functional cerebral blood flow response was restored by cholinesterase inhibition: PET study with microdialysis in the awake monkey brain
Unni_2000_Methods.Find.Exp.Clin.Pharmacol_22_57 The recovery of cerebrospinal fluid acetylcholinesterase activity in Alzheimer's disease patients after treatment with metrifonate
Yada_2000_Zoolog.Sci_17_1123 Effects of Desacetyl-alpha-MSH on Lipid Mobilization in the Rainbow Trout, Oncorhynchus mykiss
Yen_2000_Crit.Care.Med_28_2805 Spectral analysis of systemic arterial pressure and heart rate signals of patients with acute respiratory failure induced by severe organophosphate poisoning
Zhao_2000_Zhonghua.Nei.Ke.Za.Zhi_39_653 [Characters of cholinesterase are correlated with acute organophosphorus pesticide poisoning]
Zhong_2000_Zhonghua.Nei.Ke.Za.Zhi_39_658 [Alteration of banked blood cholinesterase level and its significance in emergency treatment of acute organophosphorus pesticide poisoning]
Araki_2000_Cytotech_33_93 Transgenic rabbits expressing human lipoprotein lipase
Gogol_2000_Talanta_53_379 Amperometric biosensors based on nafion coated screen-printed electrodes for the determination of cholinesterase inhibitors
Shibahara_2000_Cytotech_33_247 Mannosylerythritol lipid increases levels of galactoceramide in and neurite outgrowth from PC12 pheochromocytoma cells
van den Brink_2000_Mol.Gen.Genet_263_601 Regulation of expression of the Aspergillus niger benzoate para-hydroxylase cytochrome P450 system
Wan_2000_Talanta_52_663 Enzyme-octadecylamine Langmuir-Blodgett membranes for ENFET biosensors
Damborsky_2000_Folia.Microbiol.(Praha)_45_35 Effect of the carbon source on assessment of degrading bacteria with the spread-plating technique during in situ bioremediation
Jesenska_2000_Appl.Environ.Microbiol_66_219 Dehalogenation of haloalkanes by Mycobacterium tuberculosis H37Rv and other mycobacteria
Osman_2000_J.Egypt.Public.Health.Assoc_75_301 Effect of the carbamate aldicarb on acetyl cholinesterase extracted from whole and different parts of rat brain (in vitro and in vivo studies)
Audsley_2000_Insect.Biochem.Mol.Biol_30_681 Juvenile hormone biosynthesis by corpora allata of larval tomato moth, Lacanobia oleracea, and regulation by Manduca sexta allatostatin and allatotropin
Cusson_2000_Gen.Comp.Endocrinol_117_343 Functional significance of parasitism-induced suppression of juvenile hormone esterase activity in developmentally delayed Choristoneura fumiferana larvae
Edgar_2000_Insect.Mol.Biol_9_27 Recombinant juvenile hormone esterase, an effective tool for modifying juvenile hormone-dependent expression of the early trypsin gene in mosquitoes
Jones_2000_Biochem.J_346 Pt 1_233 Regulation of the juvenile hormone esterase gene by a composite core promoter
Nussbaumer_2000_Insect.Biochem.Mol.Biol_30_307 Isolation and characterization of juvenile hormone esterase from hemolymph of Lymantria dispar by affinity- and by anion-exchange chromatography
Shanmugavelu_2000_J.Biol.Chem_275_1802 A novel protein that binds juvenile hormone esterase in fat body tissue and pericardial cells of the tobacco hornworm Manduca sexta L
Stoltzman_2000_J.Insect.Physiol_46_771 Stage-specific production and release of juvenile hormone esterase from the ovary of Diploptera punctata
Thomas_2000_Insect.Biochem.Mol.Biol_30_529 Isolation of juvenile hormone esterase and its partial cDNA clone from the beetle, Tenebrio molitor
Dravis_2000_Biotechnol.Bioeng_69_235 Enzymatic dehalogenation of gas phase substrates with haloalkane dehalogenase
Glatz_2000_J.Chromatogr.A_895_219 Determination of haloalkane dehalogenase activity by capillary zone electrophoresis
Jaeger_2000_Curr.Opin.Chem.Biol_4_68 Directed evolution of enantioselective enzymes for organic chemistry
Lee_2000_Xenobiotica_30_1123 Effects of flupyrazofos on liver microsomal cytochrome P450 in the male Fischer 344 rat
Reetz_2000_Chemistry_6_407 Enantioselective enzymes for organic synthesis created by directed evolution
Windgassen_2000_FEMS.Microbiol.Lett_193_201 Rapid gene inactivation in Pseudomonas aeruginosa
Hayashida_2000_Genomics_66_221 Construction of a physical and transcript map flanking the imprinted MEST\/PEG1 region at 7q32
Kerjean_2000_Hum.Mol.Genet_9_2183 Establishment of the paternal methylation imprint of the human H19 and MEST\/PEG1 genes during spermatogenesis
Moralev_2000_Dokl.Biochem_375_215 New data on the structure of the acyl pocket in cholinesterases
Rozengart_2000_Zh.Evol.Biokhim.Fiziol_36_298 [Effect of the substrate structure on the backward inhibition of cholinesterases of various origin]
Elleder_2000_J.Hepatol_32_528 Subclinical course of cholesteryl ester storage disease in an adult with hypercholesterolemia, accelerated atherosclerosis, and liver cancer
Khanna_2000_Cancer.Res_60_4725 Proficient metabolism of irinotecan by a human intestinal carboxylesterase
Lohse_2000_J.Lipid.Res_41_23 Compound heterozygosity for a Wolman mutation is frequent among patients with cholesteryl ester storage disease
Morton_2000_Mol.Biotechnol_16_193 Comparison of Escherichia coli, Saccharomyces cerevisiae, Pichia pastoris, Spodoptera frugiperda, and COS7 cells for recombinant gene expression. Application to a rabbit liver carboxylesterase
Morton_2000_Cancer.Res_60_4206 Activation of CPT-11 in mice: identification and analysis of a highly effective plasma esterase
Pawlik_2000_Mol.Ther_1_457 Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated overexpression of a rabbit carboxylesterase to sensitize neuroblastoma cells to CPT-11
Potter_2000_Mol.Biotechnol_15_105 Construction of adenovirus for high level expression of small RNAs in mammalian cells. Application to a Bcl-2 ribozyme
Herrgard_2000_Biochemistry_39_2921 Role of an electrostatic network of residues in the enzymatic action of the Rhizomucor miehei lipase family
Lee_2000_J.Biomol.Struct.Dyn_18_297 Computational studies of essential dynamics of Pseudomonas cepacia lipase
Miled_2000_Biochim.Biophys.Acta_1476_165 A conformational transition between an open and closed form of human pancreatic lipase revealed by a monoclonal antibody
Katami_2000_J.Agric.Food.Chem_48_2499 Migration of organophosphorus insecticides cyanophos and prothiofos residues from impregnated paper bags to Japanese apple-pears (Pyrus pyrifolia nakai cv. Nijisseiki)
Sharma_2000_Anal.Biochem_279_85 A spectrophotometric method for assay of tannase using rhodanine
Rosenau_2000_Biochimie_82_1023 Bacterial lipases from Pseudomonas: regulation of gene expression and mechanisms of secretion
Sohaskey_2000_J.Bacteriol_182_1930 Spirochaeta aurantia has diacetyl chloramphenicol esterase activity
Fakla_2000_Neurochem.Int_36_143 Expressions of amyloid precursor protein, synaptophysin and presenilin-1 in the different areas of the developing cerebellum of rat
Garces_2000_J.Neurosci.Res_60_1 FGF9: a motoneuron survival factor expressed by medial thoracic and sacral motoneurons
Nishimune_2000_Nat.Cell.Biol_2_906 Reg-2 is a motoneuron neurotrophic factor and a signalling intermediate in the CNTF survival pathway
Silveira_2000_Brain.Res_878_223 Increased susceptibility to generalized seizures after immunolesions of the basal forebrain cholinergic neurons in rats
Tsang_2000_Brain.Res_861_45 Motor neurons are rich in non-phosphorylated neurofilaments: cross-species comparison and alterations in ALS
Uyeda_2000_Biochem.Biophys.Res.Commun_269_564 MDP77: A novel neurite-outgrowth-promoting protein predominantly expressed in chick muscles
Uyeda_2000_Neurosci.Lett_284_61 Chick muscle-derived protein 62: a novel neurite outgrowth promoting protein
Wu_2000_EMBO.J_19_1963 MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type
Brand_2000_J.Neurochem_74_1596 N-methyl bases of ethanolamine prevent apoptotic cell death induced by oxidative stress in cells of oligodendroglia origin
Glozman_2000_Biochim.Biophys.Acta_1487_135 Docosahexaenoic acid-deficient phosphatidyl serine and high alpha-tocopherol in a fetal mouse brain over-expressing Cu\/Zn-superoxide dismutase
Koudinova_2000_Neurochem.Res_25_653 Alzheimer's Abeta1-40 peptide modulates lipid synthesis in neuronal cultures and intact rat fetal brain under normoxic and oxidative stress conditions
Rabinkov_2000_Biochim.Biophys.Acta_1499_144 S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties
Puech_2000_Mol.Microbiol_35_1026 Characterization of the in vivo acceptors of the mycoloyl residues transferred by the corynebacterial PS1 and the related mycobacterial antigens 85
Li_2000_Sheng.Wu.Hua.Xue.Yu.Sheng.Wu.Wu.Li.Xue.Bao.(Shanghai)_32_183 High-efficiency Expression of Prolyl Endopeptidase from Aeromonas punctata subsp. Punctata in Escherichia coli
Gandhi_2000_Biochem.Soc.Trans_28_977 Papaya (Carica papaya) lipase with some distinct acyl and alkyl specificities as compared with microbial lipases
Weber_2000_Chem.Phys.Lipids_105_215 Antioxidants eliminate stereomutation and thioether formation during lipase-catalyzed thioesterification and transthioesterification for the preparation of uniform cis- and trans-unsaturated thioesters
Laurin_2000_Mamm.Genome_11_972 The hormone-sensitive lipase gene is transcribed from at least five alternative first exons in mouse adipose tissue
Carriere_2000_Gastroenterology_119_949 The specific activities of human digestive lipases measured from the in vivo and in vitro lipolysis of test meals
Breithaupt_2000_Z.Naturforsch.C.J.Biosci_55_971 Enzymatic hydrolysis of carotenoid fatty acid esters of red pepper (Capsicum annuum L.) by a lipase from Candida rugosa
Kumar_2000_Biomacromolecules_1_133 Candida antartica lipase B catalyzed polycaprolactone synthesis: effects of organic media and temperature
Liang_2000_J.Biol.Chem_275_24040 Importance of arginines 63 and 423 in modulating the bile salt-dependent and bile salt-independent hydrolytic activities of rat carboxyl ester lipase
Girbal_2000_Appl.Environ.Microbiol_66_1202 Reductive cleavage of demeton-S-methyl by Corynebacterium glutamicum in cometabolism on more readily metabolizable substrates
Belkner_2000_Biochem.J_352 Pt 1_125 Macrophage cholesteryl ester hydrolases and hormone-sensitive lipase prefer specifically oxidized cholesteryl esters as substrates over their non-oxidized counterparts
Harte_2000_Atherosclerosis_149_343 Low level expression of hormone-sensitive lipase in arterial macrophage-derived foam cells: potential explanation for low rates of cholesteryl ester hydrolysis
Ellis_2000_Nucleic.Acids.Res_28_377 The University of Minnesota Biocatalysis\/Biodegradation database: microorganisms, genomics and prediction
Paiva_2000_Enzyme.Microb.Technol_27_187 Kinetics and mechanisms of reactions catalyzed by immobilized lipases*
Reetz_2000_Pure.Appl.Chem_72_1615 Application of directed evolution in the development of enantioselective enzymes
Gandhi_2000_J.Agric.Food.Chem_48_566 Specificity of papaya lipase in esterification with respect to the chemical structure of substrates
Rotticci_2000_Org.Lett_2_1373 Mass transport limitations reduce the effective stereospecificity in enzyme-catalyzed kinetic resolution
Maugard_2000_Biotechnol.Prog_16_358 Study of vitamin ester synthesis by lipase-catalyzed transesterification in organic media
Xin_2000_Enzyme.Microb.Technol_26_137 Improvement of the enantioselectivity of lipase-catalyzed naproxen ester hydrolysis in organic solvent
Rader_2000_Curr.Opin.Lipidol_11_141 Endothelial lipase: a new member of the triglyceride lipase gene family
Chahinian_2000_Lipids_35_919 Kinetic properties of Penicillium cyclopium lipases studied with vinyl esters
Nawani_2000_Mol.Cell.Biochem_206_91 Purification, characterization and thermostability of lipase from a thermophilic Bacillus sp. J33
Asai_2000_Plant.Cell_12_1823 Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways
Gupta_2000_Mol.Plant.Microbe.Interact_13_503 Arabidopsis thaliana EDS4 contributes to salicylic acid (SA)-dependent expression of defense responses: evidence for inhibition of jasmonic acid signaling by SA
Edwards_2000_Insect.Mol.Biol_9_33 Characterization of a carboxypeptidase A gene from the mosquito, Aedes aegypti