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Year Report for: 2008

Aaboe_2008_Diabetes.Obes.Metab_10_994GLP-1: physiological effects and potential therapeutic applications
Aalten_2008_Dement.Geriatr.Cogn.Disord_25_1Consistency of neuropsychiatric syndromes across dementias: results from the European Alzheimer Disease Consortium. Part II
Aardema_2008_Neth.J.Med_66_149Organophosphorus pesticide poisoning: cases and developments
Abada_2008_Pak.J.Biol.Sci_11_1100Production and characterization of a mesophilic lipase isolated from Bacillus stearothermophilus AB-1
Abdel-Fattah_2008_Microbiol.Res_163_13Identification and over-expression of a thermostable lipase from Geobacillus thermoleovorans Toshki in Escherichia coli
Abdel-Latief_2008_Proc.Natl.Acad.Sci.U.S.A_105_8914An epoxide hydrolase involved in the biosynthesis of an insect sex attractant and its use to localize the production site
Abdel_2008_Neurotoxicol_29_833Effects of occupational pesticide exposure on children applying pesticides
Abdrakhmanova_2008_Neuropharmacol_55_12873'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs
Abe_2008_J.Immunol_181_7873The secretion and uptake of lysosomal phospholipase A2 by alveolar macrophages
Abe_2008_Neuropharmacol_55_1419Involvement of dopamine D2 receptors in the induction of long-term potentiation in the basolateral amygdala-dentate gyrus pathway of anesthetized rats
Abegaz_2008_Pharmacol.Res_57_87Response to the effect of aspartame on the acetylcholinesterase activity in hippocampal homogenates of suckling rats by Simintzi et al
Abel_2008_Vertex_19 Suppl_39[Treatment of Alzheimer's Disease cognitive symptoms]
Abin-Carriquiry_2008_Eur.J.Pharmacol_589_80In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: implications for Parkinson's Disease
Aboody_2008_Gene.Ther_15_739Stem and progenitor cell-mediated tumor selective gene therapy
Abou-Donia_2008_J.Toxicol.Environ.Health.A_71_119Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure
Acevedo_2008_J.Biotechnol_133_277Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique
Achard_2008_Antimicrob.Agents.Chemother_52_2767Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene
Acharya_2008_Toxicol.In.Vitro_22_525In vitro reactivation of sarin inhibited electric eel acetylcholinesterase by bis-pyridinium oximes bearing methoxy ether linkages
Acker_2008_Bioorg.Med.Chem.Lett_18_3611Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity
Adam_2008_Neurotherapeutics_5_181Symptomatic treatment of Huntington disease
Adamec_2008_Behav.Brain.Res_189_180The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice
Adams_2008_J.Bacteriol_190_8053Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii
Adkins_2008_J.Phys.Chem.B_112_4760Stable colloidal dispersions of a lipase-perfluoropolyether complex in liquid and supercritical carbon dioxide
Agelan_2008_ILAR.J_49_E8Refinement in the management of the denervated canine urinary bladder using an abdominal vesicostomy
Aggarwal_2008_Indian.J.Med.Sci_62_179Role of hyoscine N-butyl bromide (HBB, buscopan) as labor analgesic
Agrawal_2008_Behav.Brain.Res_189_381Effect of insulin and melatonin on acetylcholinesterase activity in the brain of amnesic mice
Aguedo_2008_J.Agric.Food.Chem_56_1757Enrichment of anhydrous milk fat in polyunsaturated fatty acid residues from linseed and rapeseed oils through enzymatic interesterification
Ahmad_2008_J.Enzyme.Inhib.Med.Chem_23_313Butyrylcholinesterase, lipoxygenase inhibiting and antifungal alkaloids from Isatis tinctoria
Ahmad_2008_J.Mol.Biol_381_324Thermostable Bacillus subtilis lipases: in vitro evolution and structural insight
Ahmad_2008_Pestic.Biochem.Physiol_91_24Potentiation between pyrethroid and organophosphate insecticides in resistant field populations of cotton bollworm Helicoverpa armigera (Lepidoptera: Noctuidae) in Pakistan
Ahmed_2008_J.Enzyme.Inhib.Med.Chem_23_912Comparative study of the inhibitory effect of antidepressants on cholinesterase activity in Bungarus sindanus (krait) venom, human serum and rat striatum
Ahn_2008_Bioorg.Med.Chem.Lett_18_6525Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors
Ahren_2008_Expert.Opin.Emerg.Drugs_13_593Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetes
Ahren_2008_Vasc.Health.Risk.Manag_4_383Novel combination treatment of type 2 diabetes DPP-4 inhibition + metformin
Aird_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_222Snake venom dipeptidyl peptidase IV: taxonomic distribution and quantitative variation
Ajami_2008_FEBS.Lett_582_819Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8
Akasofu_2008_Chem.Biol.Interact_175_222Study of neuroprotection of donepezil, a therapy for Alzheimer's disease
Akasofu_2008_Eur.J.Pharmacol_588_189Donepezil attenuates excitotoxic damage induced by membrane depolarization of cortical neurons exposed to veratridine
Aker_2008_Environ.Toxicol_23_548Comparing the relative toxicity of malathion and malaoxon in blue catfish Ictalurus furcatus
Akhondzadeh_2008_Prog.Neuropsychopharmacol.Biol.Psychiatry_32_1810A 12-week, double-blind, placebo-controlled trial of donepezil adjunctive treatment to risperidone in chronic and stable schizophrenia
Akiyama_2008_Am.J.Pathol_173_1349CGI-58 is an alpha/beta-hydrolase within lipid transporting lamellar granules of differentiated keratinocytes
Akuffo_2008_Biomarkers_13_618The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone
Al-Faifi_2008_Theor.Appl.Genet_117_523Exploiting synteny in Cucumis for mapping of Psm: a unique locus controlling paternal mitochondrial sorting
Al-Masri_2008_ChemMedChem_3_1763Discovery of DPP IV inhibitors by pharmacophore modeling and QSAR analysis followed by in silico screening
Al-Rehiayani_2008_Pestic.Biochem.Physiol_90_19Acetylcholinesterase in selected plant-parasitic nematodes: Inhibition, kinetic and comparative studies
Alarcon_2008_Z.Naturforsch.C_63_853Inhibition of acetylcholinesterase activity by dihydro-beta-agarofuran sesquiterpenes isolated from Chilean Celastraceae
Albayati_2008_Drug.Metab.Dispos_36_2024Pharmacokinetics of the novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat
Albuquerque_2008_Mol.Cell.Proteomics_7_1389A multidimensional chromatography technology for in-depth phosphoproteome analysis
Alexander_2008_Gene.Ther_15_831Potential of AAV vectors in the treatment of metabolic disease
Alfa_2008_Mol.Cell.Neurosci_39_400Isoform-specific contribution of protein kinase C to prion processing
Alfinito_2008_Nanotechnology_19_065202A network model to correlate conformational change and the impedance spectrum of single proteins
Algorta_2008_Methods.Find.Exp.Clin.Pharmacol_30_141Phase I clinical trial with desoxypeganine, a new cholinesterase and selective MAO-A inhibitor: tolerance and pharmacokinetics study of escalating single oral doses
Ali_2008_Chemosphere_71_1823Genotoxicity assessment of acute exposure of chlorpyrifos to freshwater fish Channa punctatus (Bloch) using micronucleus assay and alkaline single-cell gel electrophoresis
Ali_2008_Environ.Mol.Mutagen_49_374Cytogenetic damage in female Pakistani agricultural workers exposed to pesticides
Alisky_2008_Neuropsychiatr.Dis.Treat_4_831Intrathecal corticosteroids might slow Alzheimer's disease progression
Alloue_2008_Appl.Biochem.Biotechnol_150_51Comparison of Yarrowia lipolytica lipase immobilization yield of entrapment, adsorption, and covalent bond techniques
Alloue_2008_Prep.Biochem.Biotechnol_38_217Effect of monopropylene glycol and gamma irradiation on Yarrowia lipolytica lipase stabilization
Almeida_2008_Clin.Hemorheol.Microcirc_40_99Modulation of hemorheological parameters by the erythrocyte redox thiol status
Alon_2008_Insect.Biochem.Mol.Biol_38_940Organophosphates' resistance in the B-biotype of Bemisia tabaci (Hemiptera: Aleyrodidae) is associated with a point mutation in an ace1-type acetylcholinesterase and overexpression of carboxylesterase
Alonso-Vale_2008_J.Pineal.Res_45_422Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes
Alonzi_2008_Expert.Rev.Proteomics_5_91Elucidation of lipoprotein particles structure by proteomic analysis
Aloulou_2008_Aliment.Pharmacol.Ther_27_283In vitro comparative study of three pancreatic enzyme preparations: dissolution profiles, active enzyme release and acid stability
Aloulou_2008_Cell.Mol.Life.Sci_65_851Gastric lipase: an extremophilic interfacial enzyme with medical applications
Alout_2008_Chem.Biol.Interact_175_138Amino-acid substitutions in acetylcholinesterase 1 involved in insecticide resistance in mosquitoes
Alout_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_271Comparison of Anopheles gambiae and Culex pipiens acetycholinesterase 1 biochemical properties
Aluigi_2008_Cell.Biol.Toxicol_24_587The sea urchin, Paracentrotus lividus, embryo as a bioethical model for neurodevelopmental toxicity testing: effects of diazinon on the intracellular distribution of OTX2-like proteins
Alva_2008_Psychiatry.(Edgmont)_5_27Relative tolerability of Alzheimer's disease treatments
Alves_2008_Pestic.Biochem.Physiol_90_26Effects of the synergist S,S,S-tributyl phosphorotrithioate on indoxacarb toxicity and metabolism in the European corn borer, Ostrinia nubilalis (Hubner)
Aly_2008_Appl.Environ.Microbiol_74_3812Two angular dioxygenases contribute to the metabolic versatility of dibenzofuran-degrading Rhodococcus sp. strain HA01
Amadou_2008_Genome.Res_18_1472Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia
Aman_2008_Child.Adolesc.Psychiatr.Clin.N.Am_17_713Treatment of inattention, overactivity, and impulsiveness in autism spectrum disorders
Amenta_2008_Curr.Med.Chem_15_488Pathways of acetylcholine synthesis, transport and release as targets for treatment of adult-onset cognitive dysfunction
Ames_2008_Int.Psychogeriatr_20_259For debate: is the evidence for the efficacy of cholinesterase inhibitors in the symptomatic treatment of Alzheimer's disease convincing or not?
Amiri_2008_Mol.Pharmacol_73_1659A role for Leu118 of loop E in agonist binding to the alpha 7 nicotinic acetylcholine receptor
Amitai_2008_Chem.Biol.Interact_175_249Characterization of asymmetric fluorogenic phosphonates as probes for developing organophosphorus hydrolases with broader stereoselectivity
Ammazzalorso_2008_Chirality_20_115Candida rugosa lipase-catalysed kinetic resolution of 2-substituted-aryloxyacetic esters with dimethylsulfoxide and isopropanol as additives
Ammiraju_2008_Plant.Cell_20_3191Dynamic evolution of oryza genomes is revealed by comparative genomic analysis of a genus-wide vertical data set
Amoozegar_2008_J.Basic.Microbiol_48_160Production of an extracellular thermohalophilic lipase from a moderately halophilic bacterium, Salinivibrio sp. strain SA-2
Anand_2008_J.Insect.Physiol_54_1323Tissue and stage-specific juvenile hormone esterase (JHE) and epoxide hydrolase (JHEH) enzyme activities and Jhe transcript abundance in lines of the cricket Gryllus assimilis artificially selected for plasma JHE activity: implications for JHE microevolution
Anand_2008_J.Insect.Physiol_54_1404Age-dependent changes of fat body stores and the regulation of fat body lipid synthesis and mobilisation by adipokinetic hormone in the last larval instar of the cricket, Gryllus bimaculatus
Anderson_2008_J.Bacteriol_190_2957Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction
Anderson_2008_J.Cell.Physiol_215_82Morphoregulation by acetylcholinesterase in fibroblasts and astrocytes
Anderson_2008_J.Pharmacol.Exp.Ther_324_179[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]hept ane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain
Andre-Leroux_2008_Proteins_72_1298Structure-based mutagenesis of Penicillium griseofulvum xylanase using computational design
Andreani_2008_Eur.J.Med.Chem_43_657Chemiluminescent high-throughput microassay applied to imidazo[2,1-b]thiazole derivatives as potential acetylcholinesterase and butyrylcholinesterase inhibitors
Anglister_2008_Chem.Biol.Interact_175_92Cholinesterases in development and disease
Anguiano_2008_Environ.Toxicol.Chem_27_2117Enhanced esterase activity and resistance to azinphosmethyl in target and nontarget organisms
Anikienko_2008_Chem.Biol.Interact_175_286Compounds with the dioxopyrimidine cycle inhibit cholinesterases from different groups of animals
Annuzzi_2008_Nutr.Metab.Cardiovasc.Dis_18_531Postprandial chylomicrons and adipose tissue lipoprotein lipase are altered in type 2 diabetes independently of obesity and whole-body insulin resistance
Ansari_2008_Bioorg.Med.Chem_16_7691Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines
Antonio-Garcia_2008_Food.Chem.Toxicol_46_2089Toxic effects of perinatal lead exposure on the brain of rats: involvement of oxidative stress and the beneficial role of antioxidants
Antonio-Santos_2008_Curr.Opin.Ophthalmol_19_468Medical treatment options for ocular myasthenia gravis
Anzellotti_2008_Clin.Neuropharmacol_31_231Delayed blink reflex in dementia with Lewy bodies is sensitive to cholinergic modulation
Aoki_2008_Biochim.Biophys.Acta_1781_513Two pathways for lysophosphatidic acid production
Arai_2008_J.Gerontol.A.Biol.Sci.Med.Sci_63_1209Adipose endocrine function, insulin-like growth factor-1 axis, and exceptional survival beyond 100 years of age
Arakawa_2008_J.Antibiot.(Tokyo)_61_442A new terrein glucoside, a novel inhibitor of angiogenin secretion in tumor angiogenesis
Arastu-Kapur_2008_Nat.Chem.Biol_4_203Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum
Araujo_2008_Bull.Entomol.Res_98_417Enhanced activity of carbohydrate- and lipid-metabolizing enzymes in insecticide-resistant populations of the maize weevil, Sitophilus zeamais
Armenta_2008_Appl.Spectrosc_62_1322A mid-infrared flow-through sensor for label-free monitoring of enzyme inhibition
Armutlu_2008_BMC.Bioinformatics_9_411Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
Arredondo_2008_FASEB.J_22_1356Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke
Arrese_2008_Insect.Biochem.Mol.Biol_38_993Expression of lipid storage droplet protein-1 may define the role of AKH as a lipid mobilizing hormone in Manduca sexta
Asea_2008_J.Reprod.Immunol_79_12Heat shock protein-containing exosomes in mid-trimester amniotic fluids
Ashwell_2008_Somatosens.Mot.Res_25_171Topography and chemoarchitecture of the striatum and pallidum in a monotreme, the short-beaked echidna (Tachyglossus aculeatus)
Aslan_2008_Atherosclerosis_196_270Serum paraoxonase-1 activity in Helicobacter pylori infected subjects
Aslan_2008_Int.J.Clin.Pract_62_1050Serum paraoxonase and arylesterase activities for the evaluation of patients with chronic hepatitis
Assal_2008_J.Am.Geriatr.Soc_56_946Galantamine improves gait performance in patients with Alzheimer's disease
Assumpcao_2008_Insect.Biochem.Mol.Biol_38_213An insight into the sialome of the blood-sucking bug Triatoma infestans, a vector of Chagas' disease
Atoui_2008_Appl.Environ.Microbiol_74_3596Aspergillus nidulans natural product biosynthesis is regulated by mpkB, a putative pheromone response mitogen-activated protein kinase
Atri_2008_Alzheimer.Dis.Assoc.Disord_22_209Long-term course and effectiveness of combination therapy in Alzheimer disease
Atzet_2008_Biomacromolecules_9_3370Degradable poly(2-hydroxyethyl methacrylate)-co-polycaprolactone hydrogels for tissue engineering scaffolds
Auernik_2008_Appl.Environ.Microbiol_74_682The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism
Augstein_2008_Diabetes.Obes.Metab_10_850Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance
Aurilia_2008_Gene_410_234Microbial carbohydrate esterases in cold adapted environments
Avale_2008_Proc.Natl.Acad.Sci.U.S.A_105_15991Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion
Aviram_2008_J.Agric.Food.Chem_56_1148Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins
Aviram_2008_Methods.Mol.Biol_477_259Paraoxonases (PON1, PON2, PON3) analyses in vitro and in vivo in relation to cardiovascular diseases
Avlani_2008_J.Pharmacol.Exp.Ther_325_927The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions
Avogaro_2008_G.Ital.Cardiol.(Rome)_9_753[Glucagon-like peptide-1: pleiotropic effects on the cardiovascular system]
Azoulay_2008_Plant.Physiol_148_108Citrus chlorophyllase dynamics at ethylene-induced fruit color-break: a study of chlorophyllase expression, posttranslational processing kinetics, and in situ intracellular localization
Azuma_2008_J.Clin.Endocrinol.Metab_93_459Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes
Baba_2008_J.Bacteriol_190_300Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands
Bacchetta_2008_Sci.Total.Environ_392_110Axial-skeletal defects caused by Carbaryl in Xenopus laevis embryos
Backlund_2008_J.Biotechnol_135_358Fedbatch design for periplasmic product retention in Escherichia coli
Backman_2008_Anesthesiology_108_965; author reply 965Anticholinesterase drugs and the transplanted heart
Bacquet_2008_Mamm.Genome_19_439Epigenetic processes in a tetraploid mammal
Badellino_2008_Circulation_117_678Endothelial lipase is increased in vivo by inflammation in humans
Badeloe_2008_Br.J.Dermatol_158_1378Chanarin-Dorfman syndrome caused by a novel splice site mutation in ABHD5
Badiou_2008_Chem.Biol.Interact_175_406Is acetylcholinesterase a pertinent biomarker to detect exposure of pyrethroids? A study case with deltamethrin
Badiou_2008_Chem.Biol.Interact_175_410Hysteresis of insect acetylcholinesterase
Badiou_2008_Ecotoxicol.Environ.Saf_69_246Honeybee Apis mellifera acetylcholinesterase--a biomarker to detect deltamethrin exposure
Baenziger_2008_Mol.Pharmacol_73_880Lipid composition alters drug action at the nicotinic acetylcholine receptor
Baffi_2008_Mol.Biochem.Parasitol_160_70Esterase enzymes involved in pyrethroid and organophosphate resistance in a Brazilian population of Riphicephallus (Boophilus) microplus (Acari, Ixodidae)
Bafna_2008_PLoS.One_3_e2515Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-cap
Bagautdinov_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_351Structure of putative CutA1 from Homo sapiens determined at 2.05 A resolution
Bai_2008_EMBO.Rep_9_472Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits
Bailey_2008_Learn.Mem_15_261Galpha(i2) inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses
Bailey_2008_Prog.Brain.Res_169_179Synaptic remodeling, synaptic growth and the storage of long-term memory in Aplysia
Bajgar_2008_Chem.Biol.Interact_175_281An attempt to assess functionally minimal acetylcholinesterase activity necessary for survival of rats intoxicated with nerve agents
Bajnok_2008_Atherosclerosis_197_363Relationship of adiponectin to serum paraoxonase 1
Bajnok_2008_Exp.Clin.Endocrinol.Diabetes_116_592Relationship of serum resistin level to traits of metabolic syndrome and serum paraoxonase 1 activity in a population with a broad range of body mass index
Bakthavatsalam_2008_J.Cell.Sci_121_2473The secreted Dictyostelium protein CfaD is a chalone
Balali-Mood_2008_Arch.Iran.Med_11_65Neurotoxic disorders of organophosphorus compounds and their managements
Baldassarre_2008_Transgenic.Res_17_73Lactation performance of transgenic goats expressing recombinant human butyryl-cholinesterase in the milk
Baldassarre_2008_Transgenic.Res_17_863Milk composition studies in transgenic goats expressing recombinant human butyrylcholinesterase in the mammary gland
Ballard_2008_Curr.Med.Res.Opin_24_2561Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: the VantagE study
Balmayor_2008_J.Mater.Sci.Mater.Med_19_1617A novel enzymatically-mediated drug delivery carrier for bone tissue engineering applications: combining biodegradable starch-based microparticles and differentiation agents
Bandyopadhyay_2008_J.Org.Chem_73_8386Synthesis and biological evaluation of a phosphonate analog of the natural acetyl cholinesterase inhibitor cyclophostin
Banik_2008_Proc.Natl.Acad.Sci.U.S.A_105_17273Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary
Bank_2008_Front.Biosci_13_3699Inflammatory bowel diseases: multiple benefits from therapy with dipeptidyl- and alanyl-aminopeptidase inhibitors
Bannan_2008_Fly.(Austin)_2_198The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases
Baptista_2008_Biopolymers_89_538Thermodynamics and mechanism of cutinase stabilization by trehalose
Barkhimer_2008_Anal.Bioanal.Chem_392_651Electrochemical detection of acetylcholine and choline: application to the quantitative nonradiochemical evaluation of choline transport
Barnes_2008_Chest_134_1278Emerging pharmacotherapies for COPD
Barnes_2008_Curr.Opin.Pharmacol_8_300Frontrunners in novel pharmacotherapy of COPD
Barohn_2008_Ann.N.Y.Acad.Sci_1132_225Treatment and clinical research in myasthenia gravis: how far have we come?
Barten_2008_Mol.Neurobiol_37_171Therapeutic strategies for Alzheimer's disease
Barthel_2008_J.Med.Chem_51_298Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug
Barton_2008_Am.J.Geriatr.Pharmacother_6_147Contraindicated medication use among patients in a memory disorders clinic
Bartsch_2008_Angew.Chem.Int.Ed.Engl_47_1508Complete inversion of enantioselectivity towards acetylated tertiary alcohols by a double mutant of a Bacillus subtilis esterase
Baruah_2008_Br.J.Anaesth_100_420Effects of acetylcholinesterase inhibitor therapy for Alzheimer's disease on neuromuscular block
Bas_2008_Proteins_73_765Very fast prediction and rationalization of pKa values for protein-ligand complexes
Basova_2008_Dokl.Biochem.Biophys_419_69Cholinesterase hydrolysis of substituted lupinine benzoates
Bat_2008_Biomacromolecules_9_3208Trimethylene carbonate and epsilon-caprolactone based (co)polymer networks: mechanical properties and enzymatic degradation
Bates_2008_J.Anim.Sci_86_3279Differential expression in lung and bronchial lymph node of pigs with high and low responses to infection with porcine reproductive and respiratory syndrome virus
Batulevicius_2008_Auton.Neurosci_138_64Topography of the porcine epicardiac nerve plexus as revealed by histochemistry for acetylcholinesterase
Bawaskar_2008_Lancet_371_696Snakebite, cocktails, and a girl with a stomach ache
Beck_2008_Chem.Biol.Interact_175_200Hydrolysis of nerve agents by model nucleophiles: a computational study
Beck_2008_Nat.Rev.Neurosci_9_357Plasticity of intrinsic neuronal properties in CNS disorders
Beeson_2008_Ann.N.Y.Acad.Sci_1132_99Congenital myasthenic syndromes and the formation of the neuromuscular junction
Behl_2008_Int.Psychogeriatr_20_1141The effect of cholinesterase inhibitors on decline in multiple functional domains in Alzheimer's disease: a two-year observational study in the Sunnybrook dementia cohort
Beigneux_2008_J.Lipid.Res_49_1312Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase
Belbahri_2008_Gene_408_1Evolution of the cutinase gene family: evidence for lateral gene transfer of a candidate Phytophthora virulence factor
Bell_2008_Neurobiol.Aging_29_554ADAM-10 over-expression increases cortical synaptogenesis
Beller_2008_PLoS.Biol_6_e292COPI complex is a regulator of lipid homeostasis
Bello-Sani_2008_Ann.Afr.Med_7_88Myasthenia gravis associated with autoimmune thyroid disease: a report of two patients
Bellott_2008_Cancer.Chemother.Pharmacol_61_481Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene
Bembenek_2008_Bioorg.Med.Chem_16_2968Lead identification of acetylcholinesterase inhibitors-histamine H3 receptor antagonists from molecular modeling
Ben Rebah_2008_Appl.Biochem.Biotechnol_151_71Inhibitory effects of tunisian marine algal extracts on digestive lipases
Ben Rebah_2008_Lett.Appl.Microbiol_47_549Culture of Staphylococcus xylosus in fish processing by-product-based media for lipase production
Ben_2008_J.Econ.Entomol_101_484Characterization of a novel high-activity esterase in Tunisian populations of the mosquito Culex pipiens
Benabdallah_2008_Pharmacol.Res_57_132The spontaneous mechanical activity of the circular smooth muscle of the rabbit colon in vitro
Bennett_2008_Aust.N.Z.J.Psychiatry_42_662Dual constraints on synapse formation and regression in schizophrenia: neuregulin, neuroligin, dysbindin, DISC1, MuSK and agrin
Benoit_2008_Biotechnol.Lett_30_387Biotechnological applications and potential of fungal feruloyl esterases based on prevalence, classification and biochemical diversity
Bentley_2008_Brain_131_409Cholinesterase inhibition modulates visual and attentional brain responses in Alzheimer's disease and health
Bentley_2008_J.Bacteriol_190_2150Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation
Bercovich_2008_Int.J.Syst.Evol.Microbiol_58_2363Bizionia argentinensis sp. nov., isolated from surface marine water in Antarctica
Berend_2008_Arh.Hig.Rada.Toksikol_59_205[Determination of total polyphenol content in food with the flow-injection method]
Berend_2008_Chem.Biol.Interact_175_413New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning
Beres_2008_PLoS.ONE_3_E3026Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: new information about an old disease
Berger_2008_Vet.Res.Commun_32_75Effects of oral tetrachlorvinphos fly control (Equitrol) administration in horses: physiological and behavioural findings
Berk_2008_Obesity.(Silver.Spring)_16_199Higher post-absorptive skeletal muscle LPL activity in African American vs. non-Hispanic White pre-menopausal women
Berkov_2008_Bioorg.Med.Chem.Lett_18_2263N-Alkylated galanthamine derivatives: Potent acetylcholinesterase inhibitors from Leucojum aestivum
Berkov_2008_Phytochem.Anal_19_285Analysis of galanthamine-type alkaloids by capillary gas chromatography-mass spectrometry in plants
Berkov_2008_Phytochem.Anal_19_411Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts
Bermudez-Silva_2008_Diabetologia_51_476Presence of functional cannabinoid receptors in human endocrine pancreas
Bernacer_2008_J.Neural.Transm.(Vienna)_115_67Chemical architecture of the posterior striatum in the human brain
Berndt_2008_Exp.Clin.Endocrinol.Diabetes_116_203Adipose triglyceride lipase gene expression in human visceral obesity
Berny_2008_J.Wildl.Dis_44_417Acute poisoning of Red Kites (Milvus milvus) in France: data from the Sagir network
Berson_2008_Brain_131_109Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology
Berticat_2008_BMC.Evol.Biol_8_104Costs and benefits of multiple resistance to insecticides for Culex quinquefasciatus mosquitoes
Bertoni_2008_Naunyn.Schmiedebergs.Arch.Pharmacol_378_335In vitro and in vivo pharmacological analysis of imidazole-free histamine H3 receptor antagonists: promising results for a brain-penetrating H3 blocker with weak anticholinesterase activity
Bertram_2008_J.Am.Oil.Chem.Soc_85_47Characterization of Lipases and Esterases from Metagenomes for Lipid Modification
Bertrand_2008_Chem.Biol.Interact_175_113Effect of fluoxetine on neuromuscular function in acetylcholinesterase (AChE) knockout mice
Bertrand_2008_Mol.Pharmacol_74_1407Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment
Beseler_2008_Environ.Health.Perspect_116_1713Depression and pesticide exposures among private pesticide applicators enrolled in the Agricultural Health Study
Betschmann_2008_Bioorg.Med.Chem.Lett_18_3848Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists
Beyer_2008_Curr.Med.Chem_15_2748The therapeutical potential of alpha-synuclein antiaggregatory agents for dementia with Lewy bodies
Bhagwandin_2008_J.Chem.Neuroanat_35_371Nuclear organization and morphology of cholinergic, putative catecholaminergic and serotonergic neurons in the brains of two species of African mole-rat
Bhanushali_2008_Neurology_71_1335Treatment of ocular symptoms in myasthenia gravis
Bharucha_2008_Clin.Auton.Res_18_194Pilot study of pyridostigmine in constipated patients with autonomic neuropathy
Bielza_2008_J.Econ.Entomol_101_1685Impact of production system on development of insecticide resistance in Frankliniella occidentalis (Thysanoptera: Thripidae)
Bielza_2008_Pest.Manag.Sci_64_1131Insecticide resistance management strategies against the western flower thrips, Frankliniella occidentalis
Bierut_2008_Am.J.Psychiatry_165_1163Variants in nicotinic receptors and risk for nicotine dependence
Bingham_2008_Pest.Manag.Sci_64_81Temporal synergism can enhance carbamate and neonicotinoid insecticidal activity against resistant crop pests
Bionaz_2008_J.Dairy.Sci_91_2808Characterization of Madin-Darby bovine kidney cell line for peroxisome proliferator-activated receptors: temporal response and sensitivity to fatty acids
Birkus_2008_Mol.Pharmacol_74_92Activation of 9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases
Birner-Gruenberger_2008_Proteomics_8_3645Lipolytic and esterolytic activity-based profiling of murine liver
Bista_2008_Mol.Immunol_45_3618Lymphocyte quiescence factor Dpp2 is transcriptionally activated by KLF2 and TOB1
Biswal_2008_J.Mol.Biol_381_897The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor
Biswas_2008_PLoS.ONE_3_E3542Bridging the synaptic gap: neuroligins and neurexin I in Apis mellifera
Bitzopoulou_2008_Biochim.Biophys.Acta_1784_1226Mutant forms of the extracellular domain of the human acetylcholine receptor gamma-subunit with improved solubility and enhanced antigenicity. The importance of the Cys-loop
Bjarnason_2008_Hum.Exp.Toxicol_27_253Comparison of selected skin decontaminant products and regimens against VX in domestic swine
Blazer_2008_Proc.Natl.Acad.Sci.U.S.A_105_E20Acetylcholinesterase inhibition and Gulf War illnesses: conclusions are not supported by independent reviews of the same evidence
Bloch-Shilderman_2008_Toxicol.Appl.Pharmacol_231_17Subchronic exposure to low-doses of the nerve agent VX: physiological, behavioral, histopathological and neurochemical studies
Blum_2008_Biochemistry_47_5216Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase
Bocchetti_2008_Mar.Environ.Res_66_24Seasonal variations of exposure biomarkers, oxidative stress responses and cell damage in the clams, Tapes philippinarum, and mussels, Mytilus galloprovincialis, from Adriatic sea
Bodolay_2008_J.Rheumatol_35_237Evaluation of paraoxonase activity in patients with mixed connective tissue disease
Boersma_2008_Chem.Biol_15_782Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity
Boiko_2008_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_108_45[The use of axamon in the complex rehabilitation of patients with movement disorders in the pathology of lumbar spine]
Bolliger_2008_Proc.Natl.Acad.Sci.U.S.A_105_6421Unusually rapid evolution of Neuroligin-4 in mice
Bolognesi_2008_Mini.Rev.Med.Chem_8_960From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease
Bonzini_2008_Aquat.Toxicol_89_1Effects of river pollution on the colonisation of artificial substrates by macrozoobenthos
Boone_2008_Environ.Toxicol.Chem_27_1561Examining the single and interactive effects of three insecticides on amphibian metamorphosis
Borneman_2008_FEMS.Yeast.Res_8_1185Comparative genome analysis of a Saccharomyces cerevisiae wine strain
Bosak_2008_Arch.Biochem.Biophys_471_72Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol
Bosak_2008_Chem.Biol.Interact_175_192Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers
Bosak_2008_J.Enzyme.Inhib.Med.Chem_23_521Differentiation of EDTA-sensitive from EDTA-insensitive human serum esterases hydrolysing phenylacetate
Boss_2008_J.Magn.Reson.Imaging_28_1510Measurement of T1, T2, and magnetization transfer properties during embryonic development at 7 Tesla using the chicken model
Boston_2008_Int.J.Geriatr.Psychiatry_23_439Developing a simple laboratory test for Alzheimer's disease: measuring acetylcholinesterase in saliva - a pilot study
Boulin_2008_Proc.Natl.Acad.Sci.U.S.A_105_18590Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor
Bourgogne_2008_Genome.Biol_9_R110Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF
Bourne_2008_J.Psychosom.Res_65_273Drug treatment of delirium: past, present and future
Bouzat_2008_J.Neurosci_28_7808The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization
Bovet_2008_Anal.Biochem_373_380Determination of active enzyme concentration using activity-based probes and direct mass spectrometric readout
Bowler_2008_Nature_456_239The Phaeodactylum genome reveals the evolutionary history of diatom genomes
Brady_2008_BMC.Biotechnol_8_8Spherezymes: a novel structured self-immobilisation enzyme technology
Brady_2008_J.Pharmacol.Exp.Ther_327_941Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats
Brand_2008_J.Neurochem_105_1325Docosahexaenoic acid-dependent iron accumulation in oligodendroglia cells protects from hydrogen peroxide-induced damage
Brandt_2008_Acta.Crystallogr.A.Found.Crystallogr_64_C245The crystal structure of lipase a from Candida Antarctica
Brandt_2008_Peptides_29_1472Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein
Braverman_2008_J.Pharmacol.Exp.Ther_325_954The use of occupation isoboles for analysis of a response mediated by two receptors: M2 and M3 muscarinic receptor subtype-induced mouse stomach contractions
Breitbart_2008_Clin.J.Oncol.Nurs_12_27Pharmacologic treatment options for cancer-related fatigue: current state of clinical research
Brenes_2008_Poult.Sci_87_2300Effect of enzyme addition on the nutritive value of high oleic acid sunflower seeds in chicken diets
Brenner_2008_J.Neuroimmunol_201-202_121Acetylcholinesterase inhibitors and cholinergic modulation in Myasthenia Gravis and neuroinflammation
Bridges_2008_Bioorg.Med.Chem.Lett_18_5439Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties
Briggs_2008_Br.J.Pharmacol_153_1054alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues
Brigida_2008_Appl.Biochem.Biotechnol_146_173Immobilization of Candida antarctica lipase B by adsorption to green coconut fiber
Brimijoin_2008_Neuropsychopharmacology_33_2715A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats
Brischoux_2008_J.Comp.Neurol_510_607Muscarinic-2 and orexin-2 receptors on GABAergic and other neurons in the rat mesopontine tegmentum and their potential role in sleep-wake state control
Brissos_2008_Biochim.Biophys.Acta_1784_1326Biochemical and structural characterisation of cutinase mutants in the presence of the anionic surfactant AOT
Brito-Madurro_2008_Biochem.Genet_46_557A single amino acid substitution in one of the lipases of Aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid
Brkic_2008_Environ.Toxicol.Pharmacol_25_334Carbofuran in water: Subchronic toxicity to rats
Bromberg_2008_Biochim.Biophys.Acta_1784_961Kinetic study of the thermal inactivation of cholinesterase enzymes immobilized in solid matrices
Brown_2008_Biochemistry_47_5724Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis
Brown_2008_Can.Commun.Dis.Rep_34_20Absence of prolyliminopeptidase-negative Neisseria gonorroeae strains in Ontario, Canada
Brown_2008_Neurosci_154_147Dendrites of medial olivocochlear neurons in mouse
Brown_2008_SEB.Exp.Biol.Ser_60_79Amyloid peptides and ion channel function in Drosophila models of Alzheimer's disease
Bruandet_2008_Dement.Geriatr.Cogn.Disord_25_74Cognitive decline and survival in Alzheimer's disease according to education level
Brueckner_2008_J.Polym.Sci.Part.A:Polym.Chem_46_6425Enzymatic and chemical hydrolysis of poly(ethylene terephthalate) fabrics
Bruneau_2008_Curr.Biol_18_109Acetylcholine receptor clustering is required for the accumulation and maintenance of scaffolding proteins
Bruno_2008_Biochem.Biophys.Res.Commun_369_1125Clinical and genetic characterization of Chanarin-Dorfman syndrome.
Bruns_2008_Biotechnol.Bioeng_101_19Amphiphilic conetworks as activating carriers for the enhancement of enzymatic activity in supercritical CO2
Buchanan_2008_Am.J.Psychiatry_165_82Galantamine for the treatment of cognitive impairments in people with schizophrenia
Buhl_2008_J.Exp.Biol_211_2346A muscarinic cholinergic mechanism underlies activation of the central pattern generator for locust flight
Bui_2008_Chem.Biol.Interact_175_303Intrinsic conformational flexibility of acetylcholinesterase
Burcelin_2008_Diabetes.Metab_34_627What is known, new and controversial about GLP-1? Minutes of the 1st European GLP-1 Club Meeting, Marseille, 28-29 May 2008
Burdon_2008_Diab.Vasc.Dis.Res_5_128Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study
Burgdorf_2008_J.Comp.Psychol_122_357Ultrasonic vocalizations of rats (Rattus norvegicus) during mating, play, and aggression: Behavioral concomitants, relationship to reward, and self-administration of playback
Burger_2008_J.Chem.Ecol_34_659Chemical characterization of territorial marking fluid of male Bengal tiger, Panthera tigris
Burkey_2008_Diabetes.Obes.Metab_10_1057Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited
Burmeister_2008_Biosens.Bioelectron_23_1382Ceramic-based multisite microelectrode arrays for simultaneous measures of choline and acetylcholine in CNS
Burns_2008_Drugs.Aging_25_707Defining treatment response to donepezil in Alzheimer's disease: responder analysis of patient-level data from randomized, placebo-controlled studies
Burston_2008_J.Pharmacol.Exp.Ther_327_546N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase
Busek_2008_Front.Biosci_13_2319Dipeptidyl peptidase-IV enzymatic activity bearing molecules in human brain tumors--good or evil?
Busek_2008_Physiol.Res_57_443Modulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines
Butini_2008_Bioorg.Med.Chem.Lett_18_5213Tacrine based human cholinesterase inhibitors: synthesis of peptidic-tethered derivatives and their effect on potency and selectivity
Butini_2008_J.Med.Chem_51_3154Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors
Butler_2008_Curr.Med.Chem_15_1737Recent developments in the design of anti-depressive therapies: targeting the serotonin transporter
Buttemer_2008_Chemosphere_72_1315Fenitrothion, an organophosphate, affects running endurance but not aerobic capacity in fat-tailed dunnarts (Sminthopsis crassicaudata)
Buyukokuroglu_2008_Pestic.Biochem.Physiol_92_156Dantrolene may prevent organophosphate-induced oxidative stress and muscle injury
Buznikov_2008_Neurotoxicol.Teratol_30_503Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids
Byers_2008_J.Anal.Toxicol_32_57Gas chromatography-tandem mass spectrometry analysis of red blood cells from Gottingen minipig following whole-body vapor exposure to VX
Byrd_2008_Hypertension_51_141Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema
Byun_2008_Cancer.Lett_266_2382'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1
Caboni_2008_J.Agric.Food.Chem_56_7696Liquid chromatography-tandem mass spectrometric ion-switching determination of chlorantraniliprole and flubendiamide in fruits and vegetables
Cacabelos_2008_Eur.Arch.Psychiatry.Clin.Neurosci_258 Suppl 1_28Pharmacogenomics and therapeutic prospects in dementia
Cachard-Chastel_2008_Behav.Brain.Res_187_455Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice
Cahoy_2008_J.Neurosci_28_264A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function
Caimari_2008_Int.J.Obes.(Lond)_32_1193Impairment of nutritional regulation of adipose triglyceride lipase expression with age
Caixeta_2008_Rev.Bras.Psiquiatr_30_375[Dementia in Parkinsn's disease.]
Caldas_2008_Clin.Toxicol.(Phila)_46_1058Poisonings with pesticides in the Federal District of Brazil
Calic_2008_Chem.Biol.Interact_175_305Interactions of butane, but-2-ene or xylene-like linked bispyridinium para-aldoximes with native and tabun-inhibited human cholinesterases
Caliskan_2008_Anesth.Analg_106_959A prospective randomized double-blind study to determine the effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic surgery
Callanan_2008_J.Bacteriol_190_727Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion
Calvo-Garrido_2008_Mol.Biol.Cell_19_3442Vacuole membrane protein 1 is an endoplasmic reticulum protein required for organelle biogenesis, protein secretion, and development
Cambon_2008_Biotechnol.Lett_30_769Characterization of typo-, regio-, and stereo-selectivities of babaco latex lipase in aqueous and organic media
Camp_2008_J.Neurosci_28_2459Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhancesome in the first intron
Campagna_2008_Biochem.Biophys.Res.Commun_377_843Novel mutations in the adipose triglyceride lipase gene causing neutral lipid storage disease with myopathy
Campbell_2008_Diabetes.Educ_34_518More choices than ever before: emerging therapies for type 2 diabetes
Campbell_2008_Front.Biosci_13_1795CD26 inhibition and hematopoiesis: a novel approach to enhance transplantation
Camps_2008_J.Med.Chem_51_3588Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation
Cantin_2008_J.Immunol.Methods_338_21Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants
Cao_2008_Pestic.Biochem.Physiol_90_175Overexpression of carboxylesterase gene associated with organophosphorous insecticide resistance in cotton aphids, Aphis gossypii (Glover)
Carageorgiou_2008_Neuropsychiatr.Dis.Treat_4_687The effects of rivastigmine plus selegiline on brain acetylcholinesterase, (Na, K)-, Mg-ATPase activities, antioxidant status, and learning performance of aged rats
Carcoba_2008_Pharmacol.Biochem.Behav_88_374In utero methanesulfonyl fluoride differentially affects learning and maze performance in the absence of long-lasting cholinergic changes in the adult rat
Carletti_2008_J.Am.Chem.Soc_130_16011Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
Carlier_2008_Chem.Biol.Interact_175_368Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae
Carlson_2008_J.Biochem.Mol.Toxicol_22_187Distribution of SH-SY5Y human neuroblastoma cells in the cell cycle following exposure to organophosphorus compounds
Carlton_2008_Nature_455_757Comparative genomics of the neglected human malaria parasite Plasmodium vivax
Carol-Visser_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_870_91Development of an automated on-line pepsin digestion-liquid chromatography-tandem mass spectrometry configuration for the rapid analysis of protein adducts of chemical warfare agents
Carolan_2008_Chem.Biol.Interact_175_293Novel isosorbide di-ester compounds as inhibitors of acetylcholinesterase
Carr_2008_Toxicol.Sci_106_186Effect of different administration paradigms on cholinesterase inhibition following repeated chlorpyrifos exposure in late preweanling rats
Carrasco-Lopez_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_1043Crystallization and preliminary X-ray diffraction studies of the BTL2 lipase from the extremophilic microorganism Bacillus thermocatenulatus
Carstens_2008_J.Pharm.Sci_97_506A mechanistic study on the chemical and enzymatic degradation of PEG-Oligo(epsilon-caprolactone) micelles
Carswell_2008_J.Bacteriol_190_5650Expression, purification, and structural characterization of CfrA, a putative iron transporter from Campylobacter jejuni
Carta_2008_Eur.J.Neurosci_27_1220Long-term increase in GAD67 mRNA expression in the central amygdala of rats sensitized by drugs and stress
Carvalho_2008_Appl.Biochem.Biotechnol_150_25Sequential production of amylolytic and lipolytic enzymes by bacterium strain isolated from petroleum contaminated soil
Carvalho_2008_Clin.Hemorheol.Microcirc_40_207Non-neuronal cholinergic system and signal transduction pathways mediated by band 3 in red blood cells
Casanovas_2008_J.Proteome.Res_7_4173Application of proteomic tools to detect the nonspecificity of a polyclonal antibody against lipoprotein lipase
Casas_2008_J.Eukaryot.Microbiol_55_34Continuous culture of Perkinsus mediterraneus, a parasite of the European flat oyster Ostrea edulis, and characterization of its morphology, propagation, and extracellular proteins in vitro
Casida_2008_Chem.Biol.Interact_175_355Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids
Castelan_2008_J.Neurochem_105_617Molecular characterization and localization of the RIC-3 protein, an effector of nicotinic acetylcholine receptor expression
Castelli_2008_J.Bacteriol_190_213Enterobacterial common antigen integrity is a checkpoint for flagellar biogenesis in Serratia marcescens
Castro_2008_Eur.J.Pharmacol_580_339CNS-selective noncompetitive cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline
Catano_2008_Arch.Environ.Contam.Toxicol_55_153Plasma cholinesterase levels and health symptoms in peruvian farm workers exposed to organophosphate pesticides
Cattaneo_2008_Pestic.Biochem.Physiol_92_133Metabolic and histological parameters of silver catfish (Rhamdia quelen) exposed to commercial formulation of 2,4-dichlorophenoxiacetic acid (2,4-D) herbicide
Cellek_2008_Neurogastroenterol.Motil_20_539Synergy between 5-HT4 receptor activation and acetylcholinesterase inhibition in human colon and rat forestomach
Cerpa_2008_Curr.Alzheimer.Res_5_233Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses
Chabrol_2008_J.Med.Genet_45_314Deletion of C2orf34, PREPL and SLC3A1 causes atypical hypotonia-cystinuria syndrome
Chacon_2008_J.Cell.Physiol_217_215Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers
Chadman_2008_Autism.Res_1_147Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice
Chae_2008_Bioconjug.Chem_19_334Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery
Chakra_2008_Ecotoxicol.Environ.Saf_71_574Biological response of earthworm, Eisenia foetida (Savigny) to an organophosphorous pesticide, profenofos
Chakraborty_2008_J.Agric.Food.Chem_56_1428Enrichment of eicosapentaenoic acid from sardine oil with Delta5-olefinic bond specific lipase from Bacillus licheniformis MTCC 6824
Chan_2008_Drugs.Aging_25_761Transdermal delivery of treatment for Alzheimer's disease: development, clinical performance and future prospects
Chan_2008_Proc.Natl.Acad.Sci.U.S.A_105_10978Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia
Chandra_2008_Neurochem.Int_52_376Effect of novel arecoline thiazolidinones as muscarinic receptor 1 agonist in Alzheimer's dementia models
Chandrayan_2008_Protein.Expr.Purif_59_327Expression, purification, refolding and characterization of a putative lysophospholipase from Pyrococcus furiosus: retention of structure and lipase/esterase activity in the presence of water-miscible organic solvents at high temperatures
Chang_2008_Bioresour.Technol_99_2800Studies of optimum conditions for covalent immobilization of Candida rugosa lipase on poly(gamma-glutamic acid) by RSM
Chang_2008_Neurobiol.Learn.Mem_89_167Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome
Chappell_2008_Eur.Respir.J_32_931Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD
Charbonneau_2008_Curr.Med.Res.Opin_24_3287A retrospective study of cholinesterase inhibitors for Alzheimer's disease: cerebrovascular disease as a predictor of patient outcomes
Chathu_2008_Brain.Cogn_68_59Acetylcholine esterase activity and behavioral response in hypoxia induced neonatal rats: effect of glucose, oxygen and epinephrine supplementation
Chatterjee_2008_Microbiol.(Reading)_154_3338Metabolic cooperation of Gordonia sp. strain MTCC 4818 and Arthrobacter sp. strain WY in the utilization of butyl benzyl phthalate: effect of a novel co-culture in the degradation of a mixture of phthalates
Chaudhuri_2008_Infect.Immun_76_4530Amylase-binding protein B of Streptococcus gordonii is an extracellular dipeptidyl-peptidase
Che_2008_Inhal.Toxicol_20_821Blood and bronchoalveolar lavage fluid acetylcholinesterase levels following microinstillation inhalation exposure to sarin in Guinea pigs
Cheema_2008_J.Pharmacol.Exp.Ther_324_648Cholesterol regulates volume-sensitive osmolyte efflux from human SH-SY5Y neuroblastoma cells following receptor activation
Cheetham_2008_Equine.Vet.J_40_70Neuroanatomy of the equine dorsal cricoarytenoid muscle: surgical implications
Chen_2008_Appl.Biochem.Biotechnol_151_21Highly efficient regioselective synthesis of 5'-O-lauroyl-5-azacytidine catalyzed by Candida antarctica Lipase B
Chen_2008_Atherosclerosis_200_102Functional significance of lipoprotein lipase HindIII polymorphism associated with the risk of coronary artery disease
Chen_2008_Biomacromolecules_9_463Candida antarctica lipase B chemically immobilized on epoxy-activated micro- and nanobeads: catalysts for polyester synthesis
Chen_2008_Clin.Neurophysiol_119_504The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee
Chen_2008_Int.J.Obes.(Lond)_32_1694Red mold rice prevents the development of obesity, dyslipidemia and hyperinsulinemia induced by high-fat diet
Chen_2008_J.Agric.Food.Chem_56_11767Exploring the distribution of citrinin biosynthesis related genes among Monascus species
Chen_2008_J.Agric.Food.Chem_56_5639Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus
Chen_2008_J.Biol.Chem_283_25854Identification and characterization of bacterial cutinase
Chen_2008_J.Food.Sci_73_H103Effect of polysaccharide from Auricularia auricula on blood lipid metabolism and lipoprotein lipase activity of ICR mice fed a cholesterol-enriched diet
Chen_2008_J.Neurosci_28_6872Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
Chen_2008_Langmuir_24_8877Immobilization of lipases on hydrophobilized zirconia nanoparticles: highly enantioselective and reusable biocatalysts
Chen_2008_Nat.Struct.Mol.Biol_15_50Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions
Chen_2008_Nature_452_429Variations in DNA elucidate molecular networks that cause disease
Chen_2008_Pharmacol.Biochem.Behav_90_441Water-soluble derivative of propolis mitigates scopolamine-induced learning and memory impairment in mice
Chen_2008_Physiol.Res_57_119Compensatory recovery of vagal control of hemodynamics after unilateral vagotomy
Chen_2008_Plant.Sci_174_25Transgenic broccoli (Brassica oleracea var. italica) with antisense chlorophyllase (BoCLH1) delays postharvest yellowing.
Chen_2008_Taiwan.J.Obstet.Gynecol_47_283Prenatal diagnosis, fetal surgery, recurrence risk and differential diagnosis of neural tube defects
Chen_2008_Toxicology_249_194Toxicological analysis of low-nicotine and nicotine-free cigarettes
Cheng_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_295_G591Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation
Cheng_2008_Biochim.Biophys.Acta_1781_618Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase
Cheng_2008_Chem.Biol.Interact_175_196Acetylcholinesterase: mechanisms of covalent inhibition of H447I mutant determined by computational analyses
Cheng_2008_J.Pharmacol.Exp.Ther_327_683Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes
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Cheung_2008_J.Biol.Chem_283_13762Crystal structure of a functional dimer of the PhoQ sensor domain
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Chilukuri_2008_Chem.Biol.Interact_175_327Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo
Chilukuri_2008_Toxicol.Appl.Pharmacol_231_423A repeated injection of polyethyleneglycol-conjugated recombinant human butyrylcholinesterase elicits immune response in mice
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Chiu_2008_Neuropharmacol_54_68Input-specific plasticity at excitatory synapses mediated by endocannabinoids in the dentate gyrus
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Cho_2008_J.Asia.Pac.Entomol_11_117Kdr allelic variation in a sodium channel gene from a population of South Carolina Heliothis virescens (Fabricius)
Choi_2008_Appl.Microbiol.Biotechnol_79_61Production of (R)-ethyl-3,4-epoxybutyrate by newly isolated Acinetobacter baumannii containing epoxide hydrolase
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Choi_2008_Chem.Biol.Interact_175_76Regulation of PRiMA-linked G(4) AChE by a cAMP-dependent signaling pathway in cultured rat pheochromocyoma PC12 cells
Choi_2008_Dement.Geriatr.Cogn.Disord_25_445Effect of ApoE genotype on response to donepezil in patients with Alzheimer's disease
Choi_2008_J.Biol.Chem_283_11050Constitutive and agonist-induced dimerizations of the P2Y1 receptor: relationship to internalization and scaffolding
Chomsung_2008_J.Comp.Neurol_510_24Ultrastructural examination of diffuse and specific tectopulvinar projections in the tree shrew
Chou_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_1118Crystallization and preliminary X-ray diffraction analysis of phospholipase A1 isolated from hornet (Vespa basalis) venom
Chou_2008_Biomed.Chromatogr_22_502Determination of lipoprotein lipase activity in post heparin plasma of streptozotocin-induced diabetic rats by high-performance liquid chromatography with fluorescence detection
Chougule_2008_J.Cancer.Res.Ther_4_21Prognostic and diagnostic value of serum pseudocholinesterase, serum aspartate transaminase, and serum alinine transaminase in malignancies treated by radiotherapy
Chow_2008_Biologics_2_917Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome
Christiansen_2008_Mol.Biol.Evol_25_1695Nontoxic strains of cyanobacteria are the result of major gene deletion events induced by a transposable element
Christin_2008_Neurochem.Res_33_919Effects of repeated low-dose soman exposure on monoamine levels in different brain structures in mice
Christodoulou_2008_CNS.Drugs_22_87Treatment of cognitive impairment in multiple sclerosis: is the use of acetylcholinesterase inhibitors a viable option?
Christopher_2008_Clin.Ther_30_513Pharmacokinetics, pharmacodynamics, and tolerability of single increasing doses of the dipeptidyl peptidase-4 inhibitor alogliptin in healthy male subjects
Chu_2008_Mycol.Res_112_1421Identification and characterization of a lipase gene from Antrodia cinnamomea
Chuah_2008_J.Neurosci_28_11369Cholinergic augmentation modulates visual task performance in sleep-deprived young adults
Chung_2008_J.Bacteriol_190_6035Complete genome sequence of Neisseria gonorrhoeae NCCP11945
Chung_2008_J.Hepatol_48_471Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL)
Chung_2008_Microbiol.(Reading)_154_3556Determination of a transcriptional regulator-like gene involved in biosynthesis of elsinochrome phytotoxin by the citrus scab fungus, Elsino fawcettii
Ciumas_2008_Curr.Opin.Neurol_21_431Magnetic resonance imaging in clinical trials
Clark_2008_Front.Mol.Neurosci_1_8DPP6 Localization in Brain Supports Function as a Kv4 Channel Associated Protein
Clauss_2008_Plant.J_53_802Role of a GDSL lipase-like protein as sinapine esterase in Brassicaceae
Coelho_2008_Expert.Opin.Pharmacother_9_523Treatment options for non-motor symptoms in late-stage Parkinson's disease
Coelho_2008_Pediatr.Surg.Int_24_1017Studies of RET gene expression and acetylcholinesterase activity in a series of sporadic Hirschsprung's disease
Coetzer_2008_Biochimie_90_336Oligopeptidase B: a processing peptidase involved in pathogenesis
Cohen_2008_Brain.Res_1235_21Determinants of spontaneous activity in networks of cultured hippocampus
Cohen_2008_Hippocampus_18_182Transgenic inactivation of acetylcholinesterase impairs homeostasis in mouse hippocampal granule cells
Coleman_2008_Chem.Biol.Interact_175_387[+]-Huperzine A treatment protects against N-methyl-D-aspartate-induced seizure/status epilepticus in rats
Coley_2008_Neuroepidemiology_31_69Predictive factors of attrition in a cohort of Alzheimer disease patients. The REAL.FR study
Colin_2008_Biochem.Biophys.Res.Commun_370_394Exploring the active site cavity of human pancreatic lipase
Colinas_2008_J.Gen.Physiol_131_455A role for DPPX modulating external TEA sensitivity of Kv4 channels
Colletier_2008_Proc.Natl.Acad.Sci.U.S.A_105_11742Shoot-and-Trap: use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography
Colombres_2008_J.Comput.Aided.Mol.Des_22_19An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum
Comoletti_2008_Chem.Biol.Interact_175_150Characterization of the solution structure of a neuroligin/beta-neurexin complex
Conde_2008_J.Pestic.Sci_33_51Application of commercially available fenitrothion-ELISA kit for soil residue analysis
Connelly_2008_Int.J.Geriatr.Psychiatry_23_155A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease
Connelly_2008_J.Lipid.Res_49_245Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma
Connolly_2008_J.Med.Chem_51_6005Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety
Contestabile_2008_Neurochem.Res_33_318The place of choline acetyltransferase activity measurement in the cholinergic hypothesis of neurodegenerative diseases
Correa_2008_Biomed.Pharmacother_62_317Oxidative stress and erythrocyte acetylcholinesterase (AChE) in hypertensive and ischemic patients of both acute and chronic stages
Correia_2008_J.Mol.Biol_379_64Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition
Costa_2008_Appl.Spectrosc_62_932Following multi-component reactions in liquid medium using spectral band-fitting techniques
Costa_2008_Bioprocess.Biosyst.Eng_31_323Comparing the effect of immobilization methods on the activity of lipase biocatalysts in ester hydrolysis
Costantino_2008_BMC.Neurosci_9 Suppl 3_S6Intranasal administration of acetylcholinesterase inhibitors
Costas_2008_Appl.Biochem.Biotechnol_151_578Effects of organic solvents on immobilized lipase in pectin microspheres
Cotes_2008_Appl.Microbiol.Biotechnol_78_741Lipolytic enzymes in Mycobacterium tuberculosis
Couillard_2008_Arch.Environ.Contam.Toxicol_54_283Effects of diazinon on mummichog (Fundulus heteroclitus) larvae produced from eggs differentially treated with PCB126
Coulson_2008_J.Neurosci_28_315p75 neurotrophin receptor mediates neuronal cell death by activating GIRK channels through phosphatidylinositol 4,5-bisphosphate
Coutard_2008_Protein.Expr.Purif_61_184Green fluorescent protein and factorial approach: an effective partnership for screening the soluble expression of recombinant proteins in Escherichia coli
Covarrubias_2008_Neurochem.Res_33_1558The neuronal Kv4 channel complex
Covington_2008_Clin.Ther_30_499Pharmacokinetic, pharmacodynamic, and tolerability profiles of the dipeptidyl peptidase-4 inhibitor alogliptin: a randomized, double-blind, placebo-controlled, multiple-dose study in adult patients with type 2 diabetes
Crasta_2008_PLoS.ONE_3_E2193Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes
Crawford_2008_Bioorg.Chem_36_16Starter unit specificity directs genome mining of polyketide synthase pathways in fungi
Crawford_2008_Chembiochem_9_1559Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases
Crawford_2008_Science_320_243Deconstruction of iterative multidomain polyketide synthase function
Creeley_2008_Neurobiol.Aging_29_153Donepezil markedly potentiates memantine neurotoxicity in the adult rat brain
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Criniti_2008_Pestic.Biochem.Physiol_90_168Biochemical and molecular diagnosis of insecticide resistance conferred by esterase, MACE, kdr and super-kdr based mechanisms in Italian strains of the peach potato aphid, Myzus persicae (Sulzer)
Cristillo_2008_Biochem.Biophys.Res.Commun_370_22HIV-1 Env vaccine comprised of electroporated DNA and protein co-administered with Talabostat
Cronin_2008_J.Mol.Biol_383_627Insights into the catalytic mechanism of human sEH phosphatase by site-directed mutagenesis and LC-MS/MS analysis
Crossman_2008_Genome.Biol_9_R74The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants
Crow_2008_Biochim.Biophys.Acta_1781_643Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages
Croxtall_2008_Drugs_68_2387Vildagliptin: a review of its use in the management of type 2 diabetes mellitus
Csermely_2008_Curr.Med.Chem_15_2401Analysis of pyridinium aldoximes - a chromatographic approach
Cucchiaro_2008_Anesthesiology_109_512Analgesic effects of Sazetidine-A, a new nicotinic cholinergic drug
Cucurachi_2008_J.Neurol_255_1949Short-latency afferent inhibition predicts verbal memory performance in patients with multiple sclerosis
Cui_2008_Planta.Med_74_377Effect of glabridin from Glycyrrhiza glabra on learning and memory in mice
Cummings_2008_Alzheimers.Dement_4_49Behavioral effects of current Alzheimer's disease treatments: a descriptive review
Cunha_2008_Appl.Biochem.Biotechnol_146_49Immobilization of Yarrowia lipolytica lipase--a comparison of stability of physical adsorption and covalent attachment techniques
Curtin_2008_J.Cell.Biochem_103_1524Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines
Cutter_2008_Genetics_178_1661Multilocus patterns of polymorphism and selection across the X chromosome of Caenorhabditis remanei
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Cymes_2008_Nat.Struct.Mol.Biol_15_389Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer
D'Agostino_2008_Br.J.Pharmacol_154_1611Isolated porcine bronchi provide a reliable model for development of bronchodilator anti-muscarinic agents for human use
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Dabisch_2008_Cutan.Ocul.Toxicol_27_123Gender difference in the miotic potency of soman vapor in rats
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Dackovic_2008_Acta.Myol_27_59Hereditary motor and sensory neuropathy Lom type in a Serbian family
Dahlhaus_2008_J.Neurosci_28_10794Notch1 signaling in pyramidal neurons regulates synaptic connectivity and experience-dependent modifications of acuity in the visual cortex
Dai_2008_Biochem.Biophys.Res.Commun_374_485Poly-3-hydroxybutyrate synthase from the periplasm of Escherichia coli
Dai_2008_Biomacromolecules_9_1883Enzymatic preparation of novel thermoplastic di-block copolyesters containing poly[(R)-3-hydroxybutyrate] and poly(epsilon-caprolactone) blocks via ring-opening polymerization
Dai_2008_Diabetes.Obes.Metab_10_506Non-linear increase in GLP-1 levels in response to DPP-IV inhibition in healthy adult subjects
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Dalal_2008_Biotechnol.Appl.Biochem_51_23Purification and properties of the alkaline lipase from Burkholderia cepacia A.T.C.C. 25609
Damasio_2008_Aquat.Toxicol_87_310Combined use of Daphnia magna in situ bioassays, biomarkers and biological indices to diagnose and identify environmental pressures on invertebrate communities in two Mediterranean urbanized and industrialized rivers (NE Spain)
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Dandavate_2008_J.Microbiol.Biotechnol_18_735Reusability of surfactant-coated Candida rugosa lipase immobilized in gelatin microemulsion-based organogels for ethyl isovalerate synthesis
Darreh-Shori_2008_Neurobiol.Aging_29_168Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine
Darvesh_2008_J.Med.Chem_51_4200Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase
Das_2008_Biochimie_90_820Improved activity of enzymes in mixed cationic reverse micelles with imidazolium-based surfactants
Davies_2008_Clin.Toxicol.(Phila)_46_880Hypotension in severe dimethoate self-poisoning
Davies_2008_Mol.Endocrinol_22_2496The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma
Davis_2008_J.Expo.Sci.Environ.Epidemiol_18_564Assessing intermittent pesticide exposure from flea control collars containing the organophosphorus insecticide tetrachlorvinphos
Dawson_2008_J.Hazard.Mater_157_308Degradation of nerve agents by an organophosphate-degrading agent (OpdA)
De Caro_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_1Occurrence of pancreatic lipase-related protein-2 in various species and its relationship with herbivore diet
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De La Garza_2008_Int.J.Neuropsychopharmacol_11_729Evaluation of the cardiovascular and subjective effects of rivastigmine in combination with methamphetamine in methamphetamine-dependent human volunteers
De La Garza_2008_Pharmacol.Biochem.Behav_89_200The acetylcholinesterase inhibitor rivastigmine does not alter total choices for methamphetamine, but may reduce positive subjective effects, in a laboratory model of intravenous self-administration in human volunteers
De Lima_2008_Genet.Mol.Res_7_806Effects of immature cashew nut-shell liquid (Anacardium occidentale) against oxidative damage in Saccharomyces cerevisiae and inhibition of acetylcholinesterase activity
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DeBoy_2008_J.Bacteriol_190_5455Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus
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DeSantis_2008_Mini.Rev.Med.Chem_8_619Endothelial Lipase: a key player in HDL metabolism modulates inflammation and atherosclerotic risk
Deacon_2008_Curr.Opin.Investig.Drugs_9_402Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes
Deacon_2008_Front.Biosci_13_1780DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes
Debord_2008_Anal.Biochem_373_247Microcalorimetric study of the inhibition of butyrylcholinesterase by carbamates
Decker_2008_Bioorg.Med.Chem_16_4252Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties
Decker_2008_Expert.Opin.Drug.Discov_3_1027The potential of neuronal nicotinic acetylcholine receptor agonists for treating CNS conditions
Deduchovas_2008_Ann.Anat_190_525Morphologic pattern of myenteric neural plexus in colonic diverticular disease. A whole-mount study employing histochemical staining for acetylcholinesterase
Deiuliis_2008_Lipids_43_215Developmental, hormonal, and nutritional regulation of porcine adipose triglyceride lipase (ATGL)
Delgado_2008_J.Antimicrob.Chemother_62_1207The fusidic acid stimulon of Staphylococcus aureus
Deng_2008_J.Chromatogr.A_1198-1199_67Direct separation of monoacylglycerol isomers by enantioselective high-performance liquid chromatography
Denker_2008_Chem.Biol.Interact_175_125Acetylcholinesterase activity in Clytia hemisphaerica (Cnidaria)
Dephoure_2008_Proc.Natl.Acad.Sci.U.S.A_105_10762A quantitative atlas of mitotic phosphorylation
Desrosiers_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_200Ontogenesis of catabolic and energy metabolism capacities during the embryonic development of spotted wolffish (Anarhichas minor)
Detel_2008_Exp.Aging.Res_34_49The influence of age on intestinal dipeptidyl peptidase IV (DPP IV/CD26), disaccharidases, and alkaline phosphatase enzyme activity in C57BL/6 mice
Devkota_2008_J.Nat.Prod_71_1481Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana
Devkota_2008_Nat.Prod.Rep_25_612Terpenoid alkaloids of the Buxaceae family with potential biological importance
Dewan_2008_Clin.Toxicol.(Phila)_46_85Mass ethion poisoning with high mortality
Dhamija_2008_Clin.Gastroenterol.Hepatol_6_988Serologic profiles aiding the diagnosis of autoimmune gastrointestinal dysmotility
Dherbecourt_2008_Microb.Cell.Fact_7_16A genomic search approach to identify esterases in Propionibacterium freudenreichii involved in the formation of flavour in Emmental cheese
Di Giovanni_2008_Eur.J.Pharm.Sci_33_109In vitro screening assays to identify natural or synthetic acetylcholinesterase inhibitors: thin layer chromatography versus microplate methods
Diaz_2008_Chemistry_14_9261Strength enhancement of nanostructured organogels through inclusion of phthalocyanine-containing complementary organogelator structures and in situ cross-linking by click chemistry
Dichgans_2008_Lancet.Neurol_7_310Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL
Dick_2008_Appl.Environ.Microbiol_74_2646Genomic insights into Mn(II) oxidation by the marine alphaproteobacterium Aurantimonas sp. strain SI85-9A1
Dickinson_2008_Mol.Pharmacol_74_348Presynaptic alpha 7- and beta 2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms
Dierckx_2008_Acta.Clin.Belg_63_339Donepezil-related toxic hepatitis
Dieterich_2008_Nat.Genet_40_1193The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism
Dinamarca_2008_Chem.Biol.Interact_175_142Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
Ding_2008_Chem.Res.Toxicol_21_1787Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin
Ding_2008_Sheng.Wu.Gong.Cheng.Xue.Bao_24_239[Molecular cloning and characterization of an acetylcholinesterase gene Dd-ace-2 from sweet potato stem nematode Ditylenchus destructor]
Dizge_2008_Colloids.Surf.B.Biointerfaces_66_34Covalent attachment of microbial lipase onto microporous styrene-divinylbenzene copolymer by means of polyglutaraldehyde
Djeridane_2008_Chem.Biol.Interact_172_22Inhibition of porcine liver carboxylesterase by a new flavone glucoside isolated from Deverra scoparia
Djogbenou_2008_Acta.Trop_107_272Presence of insensitive acetylcholinesterase in wild populations of Culex pipiens quinquefasciatus from Benin
Djogbenou_2008_PLoS.One_3_e2172Evidence of introgression of the ace-1(R) mutation and of the ace-1 duplication in West African Anopheles gambiae s. s
Dobbins_2008_Mol.Brain_1_18alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering
Doctor_2008_Chem.Biol.Interact_175_1The IXth International Meeting on Cholinesterases, Suzhou, People's Republic of China, 6 to 10 May 2007
Doerig_2008_Trends.Parasitol_24_570Protein kinases of malaria parasites: an update
Domingues_2008_Chemosphere_71_1877In situ assay with the midge Kiefferulus calligaster for contamination evaluation in aquatic agro-systems in central Thailand
Donaldson_2008_Age.Ageing_37_237Acetylcholinesterase inhibitors and cardiovascular disease
Donati_2008_Expert.Opin.Pharmacother_9_1375Sugammadex: a cyclodextrin to reverse neuromuscular blockade in anaesthesia
Donnelly-Roberts_2008_J.Pharmacol.Exp.Ther_324_409Painful purinergic receptors
Doody_2008_CNS.Spectr_13_34Cholinesterase inhibitors and memantine: best practices
Doralp_2008_Neurobiol.Learn.Mem_90_382Cholinergic modulation of hippocampal CA1 basal-dendritic long-term potentiation
Dorandeu_2008_Toxicology_248_151An unexpected plasma cholinesterase activity rebound after challenge with a high dose of the nerve agent VX
Dorfmeister_2008_Arterioscler.Thromb.Vasc.Biol_28_1866Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding
Dougherty_2008_Neurochem.Res_33_1106Chronic nicotine alters nicotinic receptor-induced presynaptic Ca2+ responses in isolated nerve terminals
Doupis_2008_Adv.Ther_25_627DPP4 inhibitors: a new approach in diabetes treatment
Drenan_2008_Mol.Pharmacol_73_27Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled alpha6 and beta3 subunits
Drenan_2008_Neuron_60_123In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors
Dresbach_2008_Histochem.Cell.Biol_130_617Molecular architecture of glycinergic synapses
Dronca_2008_Clin.Chem.Lab.Med_46_880Serum paraoxonase 1 activities and homocysteinemia in hemodialysis patients
Du_2008_Analyst_133_1790Immobilization of acetylcholinesterase based on the controllable adsorption of carbon nanotubes onto an alkanethiol monolayer for carbaryl sensing
Du_2008_Biosens.Bioelectron_24_475Development of acetylcholinesterase biosensor based on CdTe quantum dots/gold nanoparticles modified chitosan microspheres interface
Du_2008_J.Lipid.Res_49_1646Wolman disease/cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice
Du_2008_Plant.J_56_653Functional gene-mining for salt-tolerance genes with the power of Arabidopsis
Du_2008_Talanta_74_1337In situ electrodeposited nanoparticles for facilitating electron transfer across self-assembled monolayers in biosensor design
Du_2008_Talanta_74_766Electrochemical pesticide sensitivity test using acetylcholinesterase biosensor based on colloidal gold nanoparticle modified sol-gel interface
Du_2008_Toxicol.Lett_181_104Effects of 3-benzidino-6-phenylpyridazine, as an acetylcholinesterase inhibitor, on outward potassium current in acutely isolated rat hippocampal pyramidal neurons
Dubern_2008_Mol.Biosyst_4_882Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species
Dubois_2008_Bull.Acad.Natl.Med_192_333[Alzheimer's disease: therapeutic perspectives]
Dubois_2008_Front.Biosci_13_3558Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes
Ducharme_2008_Endocrinology_149_942Lipid droplets in lipogenesis and lipolysis
Dudai_2008_Neuron_57_24Seymour Benzer (1921-2007)
Dumas_2008_Am.J.Geriatr.Psychiatry_16_272Nicotinic versus muscarinic blockade alters verbal working memory-related brain activity in older women
Duncan_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_295_G1255Distribution and function of monoacylglycerol lipase in the gastrointestinal tract
Dunlop_2008_Expert.Opin.Drug.Discov_3_623Functional screening of alpha7 nicotinic receptor ligands
Durfee_2008_J.Bacteriol_190_2597The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse
Durieux_2008_Acta.Chir.Belg_108_102Extended transsternal thymectomy for myasthenia gravis: a report of 19 consecutive cases
Dutra_2008_Appl.Biochem.Biotechnol_147_63Lipase production in solid-state fermentation monitoring biomass growth of aspergillus niger using digital image processing
Dutta_2008_Ecotoxicol.Environ.Saf_69_556Detection of pesticide by polymeric enzyme electrodes
Duysen_2008_Basic.Clin.Pharmacol.Toxicol_103_514Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice
Duysen_2008_Chem.Biol.Interact_175_119Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase
Dwoskin_2008_J.Pharmacol.Exp.Ther_326_563N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity
Dybvig_2008_Infect.Immun_76_4000Genome of Mycoplasma arthritidis
Dyck_2008_Exp.Dermatol_17_629The role of the cutaneous cholinergic system in guttate psoriasis
Dyer_2008_BMJ_336_1035Appeal Court rules that NICE procedure was unfair
Dyer_2008_Schizophr.Res_102_88High-dose galantamine augmentation inferior to placebo on attention, inhibitory control and working memory performance in nonsmokers with schizophrenia
Eaton_2008_Crit.Rev.Toxicol_38 Suppl 2_1Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment
Ebata_2008_Macromol.Biosci_8_38Lipase-catalyzed synthesis and properties of poly[(12-hydroxydodecanoate)-co-(12-hydroxystearate)] directed towards novel green and sustainable elastomers
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Eckert_2008_Biochem.Pharmacol_75_1561Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods
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Eddleston_2008_Lancet_371_597Management of acute organophosphorus pesticide poisoning
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Eilfeld_2008_Bioorg.Med.Chem_16_8127Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides
Ekici_2008_Protein.Sci_17_2023Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration
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Ela_2008_Clin.Toxicol.(Phila)_46_141Influence of atropine therapy on fenthion-induced pancreatitis
Elersek_2008_Biofouling_24_137Influence of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai on the growth of algae and wood decay fungi
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Ellerton_2008_Neurosci_153_975Induction of zinc-finger proliferation 1 expression in non-myelinating Schwann cells after denervation
Elliott_2008_Environ.Toxicol.Chem_27_452Fonofos poisons raptors and waterfowl several months after granular application
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Elmegeed_2008_Eur.J.Med.Chem_43_763Synthesis and in vivo anti-mutagenic activity of novel melatonin derivatives
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Espagne_2008_Genome.Biol_9_R77The genome sequence of the model ascomycete fungus Podospora anserina
Espallergues_2008_Chem.Biol.Interact_175_131Hyposensitivity to the amnesic effects of scopolamine or amyloid beta(25-35) peptide in heterozygous acetylcholinesterase knockout (AChE(+/-)) mice
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Eydoux_2008_Biochemistry_47_9553Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation
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Eys_2008_Antimicrob.Agents.Chemother_52_1686Three thioesterases are involved in the biosynthesis of phosphinothricin tripeptide in Streptomyces viridochromogenes Tu494
Ezoulin_2008_Neurotoxicol_29_270Antioxidative properties of galantamine on neuronal damage induced by hydrogen peroxide in SK-N-SH cells
Fagerholm_2008_Br.J.Pharmacol_154_1287alpha2A-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice
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Fain_2008_Metabolism_57_1005Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue
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Falfushinska_2008_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_148_223Different responses of biochemical markers in frogs (Rana ridibunda) from urban and rural wetlands to the effect of carbamate fungicide
Fallarero_2008_Pharmacol.Res_58_215Inhibition of acetylcholinesterase by coumarins: the case of coumarin 106
Falugi_2008_Birth.Defects.Res.C.Embryo.Today_84_188Sea urchin development: an alternative model for mechanistic understanding of neurodevelopment and neurotoxicity
Fanciulli_2008_Exp.Clin.Endocrinol.Diabetes_116_148An inhibition of the hypothalamic somatostatinergic tone is not the cause of the enhanced growth hormone response to growth hormone-releasing hormone in patients with liver cirrhosis
Fang_2008_Bioorg.Med.Chem.Lett_18_2905Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates
Fang_2008_J.Bacteriol_190_6014Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics
Fang_2008_J.Med.Chem_51_713Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates
Fang_2008_J.Med.Chem_51_7666NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity
Farahmand_2008_Circulation_118_S130Skeletal myoblasts preserve remote matrix architecture and global function when implanted early or late after coronary ligation into infarcted or remote myocardium
Farfara_2008_J.Cell.Mol.Med_12_762Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease
Farghaly_2008_Food.Chem.Toxicol_46_3111Toxicological evaluation and bioavailability of (14)C-fenitrothion bound residues on soybeans towards experimental animals
Faria_2008_Nucleosides.Nucleotides.Nucleic.Acids_27_761Decreased ecto-NTPDase1/CD39 activity leads to desensitization of P2 purinoceptors regulating tonus of corpora cavernosa in impotent men with endothelial dysfunction
Farid_2008_Toxicol.Lett_180_33Gastrointestinal nematode infection increases organophosphate toxicity in rats
Farlow_2008_Dement.Geriatr.Cogn.Disord_25_408Treatment options in Alzheimer's disease: maximizing benefit, managing expectations
Fatima_2008_Arch.Pharm.Res_31_999New butyrylcholinesterase inhibitory steroid and peroxy acid from Leucas urticifolia
Fatima_2008_Protein.Pept.Lett_15_346Characterization of fluoroalcohols-induced intermediates of Mucor miehei lipase at low pH
Faure_2008_Toxicon_52_400Obituary: Cassian Bon a scientist fascinated by toxins and their therapeutic potential
Favero_2008_J.Physiol_586_4763Expression of small-conductance calcium-activated potassium channels (SK3) in skeletal muscle: regulation by muscle activity
Febbraio_2008_Extremophiles_12_719Irreversible inhibition of the thermophilic esterase EST2 from Alicyclobacillus acidocaldarius
Fedi_2008_Neurology_71_795Reduced striatal D1 receptor binding in autosomal dominant nocturnal frontal lobe epilepsy
Fedorova_2008_PLoS.Genet_4_E1000046Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus
Fehling_2008_Biotechnol.Bioeng_99_1074Linear copolymeric poly(thia-alkanedioates) by lipase-catalyzed esterification and transesterification of 3,3'-thiodipropionic acid and its dimethyl ester with alpha,omega-alkanediols
Feng_2008_PLoS.ONE_3_E4053A recalibrated molecular clock and independent origins for the cholera pandemic clones
Feng_2008_Pestic.Biochem.Physiol_92_107Effects of trichlorfon and sodium dodecyl sulphate on antioxidant defense system and acetylcholinesterase of Tilapia nilotica in vitro
Fernandez-Gomez_2008_Chem.Biol.Interact_175_332The level of butyrylcholinesterase activity increases and the content of the mRNA remains unaffected in brain of senescence-accelerated mouse SAMP8
Fernandez-Lorente_2008_Biomacromolecules_9_2553Solid-phase chemical amination of a lipase from Bacillus thermocatenulatus to improve its stabilization via covalent immobilization on highly activated glyoxyl-agarose
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Fernandez_2008_Biochim.Biophys.Acta_1781_367Lipolysis of the semi-solid self-emulsifying excipient Gelucire 44/14 by digestive lipases
Fernyhough_2008_Cells.Tissues.Organs_188_359Progeny from dedifferentiated bovine adipocytes display protracted adipogenesis
Ferrero_2008_Expert.Rev.Neurother_8_979Myasthenia gravis during pregnancy
Ferretti_2008_Clin.Biochem_41_381Lipid peroxidation in hemodialysis patients: effect of vitamin C supplementation
Ferretti_2008_Clin.Chem.Lab.Med_46_113Lipid peroxidation in stroke patients
Fex_2008_Biochem.Soc.Trans_36_885Lipases in the pancreatic beta-cell: implications for insulin secretion
Fife_2008_J.Pharmacol.Exp.Ther_327_707Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation
Figiel_2008_Curr.Med.Res.Opin_24_157A systematic review of the effectiveness of rivastigmine for the treatment of behavioral disturbances in dementia and other neurological disorders
Figiel_2008_Prim.Care.Companion.J.Clin.Psychiatry_10_291Safety and efficacy of rivastigmine in patients with Alzheimer's disease not responding adequately to donepezil: an open-label study
Filippatos_2008_Drug.Saf_31_53Orlistat-associated adverse effects and drug interactions: a critical review
Finsterer_2008_J.Neurol.Sci_272_20Cognitive decline as a manifestation of mitochondrial disorders (mitochondrial dementia)
Firth-Clark_2008_J.Chem.Inf.Model_48_296De novo ligand design to partially flexible active sites: application of the ReFlex algorithm to carboxypeptidase A, acetylcholinesterase, and the estrogen receptor
Fisher_2008_Ann.Pharmacother_42_278Prolonged QT interval, syncope, and delirium with galantamine
Fisher_2008_Neurotherapeutics_5_433Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease
FitzGerald_2008_Cogn.Behav.Neurol_21_57Effects of donepezil on verbal memory after semantic processing in healthy older adults
Flatt_2008_Front.Biosci_13_3648Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes
Fleck_2008_Arzneimittelforschung_58_543A new way of data interpretation for cognition tests in rats used to characterise six choline esterase inhibitors with heterocyclic nitrogen bridgehead structure. Application in Alzheimer therapy
Fleury_2008_Rev.Prat_58_2217[Myasthenia gravis]
Florjancic_2008_Bioorg.Med.Chem.Lett_18_2089Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists
Fluxa_2008_Nat.Protoc_3_1270Enzyme assay and activity fingerprinting of hydrolases with the red-chromogenic adrenaline test
Fock_2008_Exp.Hematol_36_78NF-E2-mediated enhancement of megakaryocytic differentiation and platelet production in vitro and in vivo
Focosi_2008_J.Leukoc.Biol_84_331Conditioning response to granulocyte colony-stimulating factor via the dipeptidyl peptidase IV-adenosine deaminase complex
Fodale_2008_Crit.Care.Med_36_622Cholinesterase inhibitors improve survival in experimental sepsis: a new way to activate the cholinergic anti-inflammatory pathway
Foote_2008_J.Bacteriol_190_1495The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)
Ford_2008_J.Agric.Food.Chem_56_10168Comparative metabolism and pharmacokinetics of seven neonicotinoid insecticides in spinach
Forette_2008_Bull.Acad.Natl.Med_192_363[Alzheimer's disease: from brain lesions to new drugs]
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Forssmann_2008_J.Immunol_181_1120Inhibition of CD26/dipeptidyl peptidase IV enhances CCL11/eotaxin-mediated recruitment of eosinophils in vivo
Forstl_2008_Internist.(Berl)_49_353[Antidementia drugs--response or non-response?]
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Fortunato_2008_Arterioscler.Thromb.Vasc.Biol_28_594Decreased paraoxonase-2 expression in human carotids during the progression of atherosclerosis
Foster_2008_J.Clin.Microbiol_46_296Real-time PCR assays of single-nucleotide polymorphisms defining the major Brucella clades
Foster_2008_J.Pharmacol.Exp.Ther_325_457Activation of muscarinic cholinergic receptors on human SH-SY5Y neuroblastoma cells enhances both the influx and efflux of K+ under conditions of hypo-osmolarity
Foster_2008_Pest.Manag.Sci_64_1111Correlated responses to neonicotinoid insecticides in clones of the peach-potato aphid, Myzus persicae (Hemiptera: Aphididae)
Foulkes_2008_Stat.Med_27_2784Mixed modeling and multiple imputation for unobservable genotype clusters
Fouts_2008_PLoS.Genet_4_e1000141Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice
Fowler_2008_Behav.Pharmacol_19_461Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice
Francischetti_2008_Insect.Biochem.Mol.Biol_38_1An insight into the sialome of the soft tick, Ornithodorus parkeri
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Franco-Pons_2008_J.Gastrointest.Surg_12_891Serum paraoxonase undergoes inhibition and proteolysis during experimental acute pancreatitis
Frasco_2008_Sci.Total.Environ_404_88Does mercury interact with the inhibitory effect of dichlorvos on Palaemon serratus (Crustacea: Decapoda) cholinesterase?
Frazier_2008_Naunyn.Schmiedebergs.Arch.Pharmacol_377_449Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and beta-adrenoceptors
Frederick_2008_Febs.J_275_1309Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide
Frederiksen_2008_Scand.J.Urol.Nephrol_42_205Nerve distribution in rat urinary bladder after incorporation of acellular matrix graft or subtotal cystectomy
Freedman_2008_Am.J.Psychiatry_165_1040Initial phase 2 trial of a nicotinic agonist in schizophrenia
Freeling_2008_Exp.Physiol_93_75Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload
Freeman_2008_Biological.Bulletin_214_284cDNA sequences for transcription factors and signaling proteins of the hemichordate Saccoglossus kowalevskii: efficacy of the expressed sequence tag (EST) approach for evolutionary and developmental studies of a new organism
Fregolente_2008_Appl.Biochem.Biotechnol_146_165Monoglycerides and diglycerides synthesis in a solvent-free system by lipase-catalyzed glycerolysis
Frenzilli_2008_Aquat.Toxicol_89_188Cellular responses in the cyprinid Leuciscus cephalus from a contaminated freshwater ecosystem
Fricke_2008_J.Bacteriol_190_6779Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5
Frikha_2008_FEMS.Microbiol.Lett_286_2073-D structure modelling of the Staphylococcus simulans lipase: conformational changes, substrate specificity and novel structural features
Fruchart-Gaillard_2008_Mol.Pharmacol_74_1554Different interactions between MT7 toxin and the human muscarinic M1 receptor in its free and N-methylscopolamine-occupied states
Frueh_2008_Nature_454_903Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase
Fu_2008_Enzyme.Microb.Technol_42_187A novel cold-adapted phospholipase A(1) from Serratia sp. xjF1: Gene cloning, expression and characterization
Fuchu_2008_Appl.Microbiol.Biotechnol_79_627Insertion sequence-based cassette PCR: cultivation-independent isolation of gamma-hexachlorocyclohexane-degrading genes from soil DNA
Fuh_2008_Acta.Neurol.Taiwan_17_153Dementia in Taiwan: past, present, and future
Fuhrman_2008_Arterioscler.Thromb.Vasc.Biol_28_1361Urokinase plasminogen activator upregulates paraoxonase 2 expression in macrophages via an NADPH oxidase-dependent mechanism
Fujii_2008_Am.J.Nephrol_28_974Putative role of endothelial lipase in dialysis patients with hypoalbuminemia and inflammation
Fujii_2008_J.Pharmacol.Sci_106_186Basic and clinical aspects of non-neuronal acetylcholine: expression of an independent, non-neuronal cholinergic system in lymphocytes and its clinical significance in immunotherapy
Fujiki_2008_J.Clin.Neurosci_15_791Neuroprotective and antiamnesic effect of donepezil, a nicotinic acetylcholine-receptor activator, on rats with concussive mild traumatic brain injury
Fujimoto_2008_Bioorg.Med.Chem.Lett_18_1106Cy3-3-acylcholine: a fluorescent analogue of acetylcholine for single molecule detection
Fujiyoshi_2008_Curr.Opin.Struct.Biol_18_587Electron crystallography of proteins in membranes
Fukami_2008_Pharmacogenet.Genomics_18_911Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes
Fukushima_2008_Bioorg.Med.Chem_16_4093Synthesis and structure-activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
Fukushima_2008_Chem.Pharm.Bull.(Tokyo)_56_1110Synthesis and structure-activity relationships of potent 1-(2-substituted-aminoacetyl)-4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
Funk_2008_Eur.J.Anaesthesiol_25_37Physostigmine and anaesthesia emergence delirium in preschool children: a randomized blinded trial
Furlani_2008_Auton.Neurosci_144_30Morphological and quantitative study of ganglionated plexus of Calomys callosus trachea
Furne_2008_Comp.Biochem.Physiol.A.Mol.Integr.Physiol_149_420Effect of starvation and refeeding on digestive enzyme activities in sturgeon (Acipenser naccarii) and trout (Oncorhynchus mykiss)
Furtado-Alle_2008_Chem.Biol.Interact_175_115Association of variants of the -116 site of the butyrylcholinesterase BCHE gene to enzyme activity and body mass index
Gabrovska_2008_Int.J.Biol.Macromol_43_339The influence of the support nature on the kinetics parameters, inhibition constants and reactivation of immobilized acetylcholinesterase
Gaeta_2008_Skeletal.Radiol_37_1053Opposed-phase MR imaging of lipid storage myopathy in a case of Chanarin-Dorfman disease
Gagliardino_2008_Expert.Opin.Pharmacother_9_1495New treatments for type 2 diabetes mellitus: combined therapy with sitagliptin
Gagnaire_2008_Chemosphere_71_553Cholinesterase activities as potential biomarkers: characterization in two freshwater snails, Potamopyrgus antipodarum (Mollusca, Hydrobiidae, Smith 1889) and Valvata piscinalis (Mollusca, Valvatidae, Muller 1774)
Gahring_2008_Hippocampus_18_737Nicotinic acetylcholine receptor expression in the hippocampus of 27 mouse strains reveals novel inhibitory circuitry
Gajsek_2008_Chem.Biol.Interact_175_50Synaptogenetic mechanisms controlling postsynaptic differentiation of the neuromuscular junction are nerve-dependent in human and nerve-independent in mouse C2C12 muscle cultures
Galindo-Charles_2008_Synapse_62_601Serotoninergic dorsal raphe neurons possess functional postsynaptic nicotinic acetylcholine receptors
Gallwitz_2008_IDrugs_11_906Saxagliptin, a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Galvin_2008_Alzheimer.Dis.Assoc.Disord_22_30Effects of galantamine on measures of attention: results from 2 clinical trials in Alzheimer disease patients with comparisons to donepezil
Galvin_2008_Pediatr.Dev.Pathol_11_185A murine model of infantile neuronal ceroid lipofuscinosis-ultrastructural evaluation of storage in the central nervous system and viscera
Gamsjager_2008_Clin.Chem.Lab.Med_46_1140Half-lives of albumin and cholinesterase in critically ill patients
Gao_2008_Chem.Biol.Interact_175_83An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties
Gao_2008_J.Med.Chem_51_4751Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2 .1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties
Garber_2008_Diabetes.Obes.Metab_10_1047Effects of vildagliptin on glucose control in patients with type 2 diabetes inadequately controlled with a sulphonylurea
Garber_2008_Expert.Opin.Investig.Drugs_17_105Update: vildagliptin for the treatment of Type 2 diabetes
Garcia-Ayllon_2008_Brain_131_2946Brain cholinergic impairment in liver failure
Garcia-Ayllon_2008_Chem.Biol.Interact_175_209Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid
Garcia-Palomero_2008_Neurodegener.Dis_5_153Potent beta-amyloid modulators
Garcia-Soria_2008_Diabetes.Obes.Metab_10_293The dipeptidyl peptidase-4 inhibitor PHX1149 improves blood glucose control in patients with type 2 diabetes mellitus
Garcia_2008_Clin.Biochem_41_474Butyrylcholinesterase activity is reduced in haemodialysis patients: is there association with hyperhomocysteinemia and/or oxidative stress?
Gardner_2008_J.Biol.Chem_283_17099Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein
Gartemann_2008_J.Bacteriol_190_2138The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity
Gatti-Lafranconi_2008_FEBS.Lett_582_2313Unscrambling thermal stability and temperature adaptation in evolved variants of a cold-active lipase
Gaur_2008_Appl.Biochem.Biotechnol_151_160Protein-coated microcrystals of Pseudomonas aeruginosa PseA lipase
Gautier_2008_Diabetes.Metab_34 Suppl 2_S65Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes
Gautier_2008_J.Pharmacol.Exp.Ther_324_149Calcium-activated potassium channels in insect pacemaker neurons as unexpected target site for the novel fumigant dimethyl disulfide
Gay_2008_J.Pharmacol.Exp.Ther_327_884Inhibition of native and recombinant nicotinic acetylcholine receptors by the myristoylated alanine-rich C kinase substrate peptide
Gay_2008_J.Physiol_586_1105Aromatic residues at position 55 of rat alpha7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization
Gazic_2008_Anal.Bioanal.Chem_385_1513Preparative HPLC separation of bambuterol enantiomers and stereoselective inhibition of human cholinesterases
Ge_2008_Chemistry_14_376Hopeahainol A: an acetylcholinesterase inhibitor from Hopea hainanensis
Ge_2008_J.Phys.Chem.B_112_14319Molecular fundamentals of enzyme nanogels
Geerling_2008_Transplantation_85_135Innervation and secretory function of transplanted human submandibular salivary glands
Gekel_2008_J.Neurosci_28_7991Application of an Epac activator enhances neurotransmitter release at excitatory central synapses
Geng_2008_Chem.Biol.Interact_175_108Transmembrane mechanisms in the assembly of the postsynaptic apparatus at the neuromuscular junction
Genovese_2008_Toxicology_244_123Determination of miosis threshold from whole-body vapor exposure to sarin in African green monkeys
Georgiev_2008_Prilozi_29_213Association of PvuII polymorphism in the lipoprotein lipase gene with the coronary artery disease in Macedonian population
Geula_2008_J.Neuropathol.Exp.Neurol_67_309Cholinergic neuronal and axonal abnormalities are present early in aging and in Alzheimer disease
Geyer_2008_Chem.Biol.Interact_175_376Increased organophosphate scavenging in a butyrylcholinesterase mutant
Ghadamyari_2008_J.Econ.Entomol_101_1432Oxydemeton-methyl resistance, mechanisms, and associated fitness cost in green peach aphids (Hemiptera: Aphididae)
Ghadimi_2008_J.Enzyme.Inhib.Med.Chem_23_213Synthesis, lipophilicity study and in vitro evaluation of some rodenticides as acetylcholinesterase reversible inhibitors
Ghadimi_2008_J.Enzyme.Inhib.Med.Chem_23_556Structure-activity study of phosphoramido acid esters as acetylcholinesterase inhibitors
Ghareeb_2008_Neurosci.Lett_436_44Vanadium improves brain acetylcholinesterase activity on early stage alloxan-diabetic rats
Ghedini_2008_Muscle.Nerve_38_1585Increased expression of acetylcholine receptors in the diaphragm muscle of MDX mice
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Grisvard_2008_Eur.J.Protistol_44_278Differentially expressed genes during the encystment-excystment cycle of the ciliate Sterkiella histriomuscorum
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Gross_2008_BMC.Genomics_9_449The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae
Grossberg_2008_Drugs.Aging_25_573Impact of rivastigmine on caregiver burden associated with Alzheimer's disease in both informal care and nursing home settings
Grucza_2008_Biol.Psychiatry_64_922A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence
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Guay_2008_Consult.Pharm_23_598Rivastigmine transdermal patch: role in the management of Alzheimer's disease
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Gumilar_2008_Eur.J.Pharmacol_584_30Tricyclic antidepressants inhibit homomeric Cys-loop receptors by acting at different conformational states
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Gurusubramanian_2008_J.Environ.Biol_29_813Pesticide usage pattern in tea ecosystem, their retrospects and alternative measures
Gutierrez_2008_Plant.Biol.(Stuttg)_10_398A possible role of prolyl oligopeptidase during Linum usitatissimum (flax) seed development
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Gyengesi_2008_Brain.Res.Bull_75_570The effect of prefrontal stimulation on the firing of basal forebrain neurons in urethane anesthetized rat
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Haider_2008_Appl.Biochem.Biotechnol_144_225Artificial neural network-genetic algorithm approach to optimize media constituents for enhancing lipase production by a soil microorganism
Haidet_2008_Proc.Natl.Acad.Sci.U.S.A_105_4318Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors
Haigh_2008_Chem.Biol.Interact_175_380Protection of red blood cell acetylcholinesterase by oral huperzine A against ex vivo soman exposure: next generation prophylaxis and sequestering of acetylcholinesterase over butyrylcholinesterase
Haigh_2008_Chem.Biol.Interact_175_417Advantages of the WRAIR whole blood cholinesterase assay: comparative analysis to the micro-Ellman, Test-mate ChE, and Michel (DeltapH) assays
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Harati_2008_Neurosci_153_72Selective cholinergic lesions in the rat nucleus basalis magnocellularis with limited damage in the medial septum specifically alter attention performance in the five-choice serial reaction time task
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Harmon_2008_Dev.Psychobiol_50_322Rats selectively bred for low levels of 50 kHz ultrasonic vocalizations exhibit alterations in early social motivation
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Harris_2008_Cell.Signal_20_2296The interferon-gamma-mediated inhibition of lipoprotein lipase gene transcription in macrophages involves casein kinase 2- and phosphoinositide-3-kinase-mediated regulation of transcription factors Sp1 and Sp3
Harris_2008_DNA.Cell.Biol_27_467Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence
Hartl_2008_Langmuir_24_9898Enzyme-modified field effect transistors based on surface-conductive single-crystalline diamond
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Hasegawa_2008_BMC.Dev.Biol_8_71The PPARgamma-selective ligand BRL-49653 differentially regulates the fate choices of rat calvaria versus rat bone marrow stromal cell populations
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Hasson_2008_Neuron_57_452Enhanced intersubject correlations during movie viewing correlate with successful episodic encoding
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Havre_2008_Front.Biosci_13_1634The role of CD26/dipeptidyl peptidase IV in cancer
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Hazarika_2008_Clin.Cancer.Res_14_5325Tasigna for chronic and accelerated phase Philadelphia chromosome--positive chronic myelogenous leukemia resistant to or intolerant of imatinib
He_2008_J.Clin.Pharmacol_48_85Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects
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Hejnol_2008_Nature_456_382Acoel development indicates the independent evolution of the bilaterian mouth and anus
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Hernandez_2008_J.Physiol_586_1811Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications
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Hodgson_2008_Pest.Manag.Sci_64_617Metabolic interactions of agrochemicals in humans
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Hogan_2008_CMAJ_179_1019Diagnosis and treatment of dementia: 5. Nonpharmacologic and pharmacologic therapy for mild to moderate dementia
Hoguet_2008_J.Environ.Sci.Health.B_43_465Baseline activities of four biomarkers in three life-stages of the amphipod, Leptocheirus plumulosus
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Holmes_2008_BMC.Evol.Biol_8_54Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor
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Holtzheimer_2008_Int.J.Geriatr.Psychiatry_23_625A double blind, placebo-controlled pilot study of galantamine augmentation of antidepressant treatment in older adults with major depression
Hong_2008_Planta_227_539Function of a novel GDSL-type pepper lipase gene, CaGLIP1, in disease susceptibility and abiotic stress tolerance
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Hoover_2008_Bioorg.Med.Chem.Lett_18_5838Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling
Horenstein_2008_Mol.Pharmacol_74_1496Multiple pharmacophores for the selective activation of nicotinic alpha7-type acetylcholine receptors
Horne_2008_Gene_411_27Multiple tandem gene duplications in a neutral lipase gene cluster in Drosophila
Hornick_2008_Biochem.Pharmacol_76_236Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: brain ACh increasing and memory improving properties
Horton_2008_Endocr.Pract_14_625Can newer therapies delay the progression of type 2 diabetes mellitus?
Hosokawa_2008_Drug.Metab.Pharmacokinet_23_73Structural organization and characterization of the regulatory element of the human carboxylesterase (CES1A1 and CES1A2) genes
Hosokawa_2008_Molecules_13_412Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs
Hosseini_2008_Indian.J.Gastroenterol_27_99Role of rectal biopsy in predicting response to intrasphincteric botulinum toxin injection for obstructive symptoms after a pullthrough operation
Hou_2008_Biol.Direct_3_26Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia
Hou_2008_Endocr.Pract_14_1020A case of severe neuropathy associated with hypertriglyceridemia
Hrobak_2008_AANA.J_76_95Nerve agents: implications for anesthesia providers
Hsiao_2008_J.Neurophysiol_99_999Zinc potentiates neuronal nicotinic receptors by increasing burst duration
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Hu_2008_J.Bacteriol_190_2892Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species
Hu_2008_J.Neurochem_106_1371Role of GSK-3beta activation and alpha7 nAChRs in Abeta(1-42)-induced tau phosphorylation in PC12 cells
Hu_2008_Respirology_13_837Association between polymorphisms of microsomal epoxide hydrolase and COPD: results from meta-analyses
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Huang_2008_J.Med.Chem_51_6293Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding
Huang_2008_Learn.Mem_15_603Chronic nicotine exposure induces a long-lasting and pathway-specific facilitation of LTP in the amygdala
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Huizinga_2008_Plant.Cell_20_2714Isoprenylcysteine methylation and demethylation regulate abscisic acid signaling in Arabidopsis
Hung_2008_Biol.Pharm.Bull_31_159Anti-amnestic activity of pseudocoptisine from Corydalis Tuber
Hung_2008_J.Ethnopharmacol_119_74Cholinesterase inhibitory and anti-amnesic activity of alkaloids from Corydalis turtschaninovii
Hunsen_2008_Biomacromolecules_9_518Humicola insolens cutinase-catalyzed lactone ring-opening polymerizations: kinetic and mechanistic studies
Husain_2008_Neuropsychiatr.Dis.Treat_4_765Present and prospective clinical therapeutic regimens for Alzheimer's disease
Huxley_2008_Biochem.Biophys.Res.Commun_369_34Memories of early work on muscle contraction and regulation in the 1950's and 1960's
Hwang_2008_Mar.Biotechnol.(NY)_10_366Screening enantioselective epoxide hydrolase activities from marine microorganisms: detection of activities in Erythrobacter spp
Hyun_2008_Dev.Cell_14_183Cooperation and functional diversification of two closely related galactolipase genes for jasmonate biosynthesis
Iacono_2008_Antimicrob.Agents.Chemother_52_2616Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group
Ibrahim_2008_J.Pharm.Biomed.Anal_48_1345Association mechanism of four acetylcholinesterase inhibitors (AChEIs) with human serum albumin: a biochromatographic approach
Ihara_2008_Invert.Neurosci_8_71Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin
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Imamura_2008_Neurocase_14_271The effect of donepezil on increased regional cerebral blood flow in the posterior cingulate cortex of a patient with Parkinson's disease dementia
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Inzucchi_2008_Circulation_117_574New drugs for the treatment of diabetes: part II: Incretin-based therapy and beyond
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Isik_2008_Pestic.Biochem.Physiol_92_38Acute effects of methyl parathion and diazinon as inducers for oxidative stress on certain biomarkers in various tissues of rainbowtrout (Oncorhynchus mykiss)
Ito_2008_Brain.Res_1201_78Some gamma-motoneurons contain gamma-aminobutyric acid in the rat cervical spinal cord
Ito_2008_Chem.Biol.Interact_175_346Viral vector-mediated [corrected] expression of human collagen Q in cultured cells
Ito_2008_PPAR.Res_2008_759716PPARalpha- and DEHP-Induced Cancers
Itou_2008_J.Gastroenterol.Hepatol_23_244Altered expression of glucagon-like peptide-1 and dipeptidyl peptidase IV in patients with HCV-related glucose intolerance
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Ivy_2008_Bioorg.Med.Chem_16_746Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs
Iwamoto_2008_Syst.Appl.Microbiol_31_269Identification and cloning of a gene encoding tannase (tannin acylhydrolase) from Lactobacillus plantarum ATCC 14917(T)
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Iyer_2008_J.Org.Chem_73_4819The effects of sulfur substitution for the nucleophile and bridging oxygen atoms in reactions of hydroxyalkyl phosphate esters
Jackson_2008_Clin.Exp.Pharmacol.Physiol_35_29Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure
Jackson_2008_Hypertension_51_1637Sitagliptin augments sympathetic enhancement of the renovascular effects of angiotensin II in genetic hypertension
Jackson_2008_J.Mol.Biol_375_1189In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase
Jackson_2008_J.Pharmacol.Exp.Ther_325_302Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs
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Jain_2008_Toxicol.Appl.Pharmacol_230_247Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer
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Jang_2008_Arch.Pharm.Res_31_666A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta
Jang_2008_Phytother.Res_22_544Inhibition of cholinesterase and amyloid-beta aggregation by resveratrol oligomers from Vitis amurensis
Jankowska-Kulawy_2008_Acta.Neurobiol.Exp.(Wars)_68_453Effects of lead on cholinergic SN56 neuroblastoma cells
Janssen_2008_Dev.Genes.Evol_218_361Evidence for Wg-independent tergite boundary formation in the millipede Glomeris marginata
Jara-Oseguera_2008_J.Gen.Physiol_132_547Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums
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Jayasundara_2008_Bull.Environ.Contam.Toxicol_80_374Effect of repeated application of fenthion as a mosquito larvicide on Nile tilapia (Oreochromis niloticus) inhabiting selected water canals in Sri Lanka
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Jean_2008_PLoS.One_3_e1834Structural elements regulating amyloidogenesis: a cholinesterase model system
Jelani_2008_Clin.Genet_74_184A novel deletion mutation in LIPH gene causes autosomal recessive hypotrichosis (LAH2)
Jemec_2008_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_147_61Biochemical biomarkers in chronically metal-stressed daphnids
Jencova_2008_Res.Microbiol_159_118Nucleotide sequence, organization and characterization of the (halo)aromatic acid catabolic plasmid pA81 from Achromobacter xylosoxidans A8
Jennings_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_149_401Acetylcholinesterase in the sea urchin Lytechinus variegatus: characterization and developmental expression in larvae
Jensen_2008_J.Lipid.Res_49_870Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype?
Jeong_2008_Appl.Biochem.Biotechnol_148_131Lipase-catalyzed transesterification of rapeseed oil for biodiesel production with tert-butanol
Jeong_2008_Cell.Metab_7_227Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
Jeong_2008_Eur.J.Pharmacol_588_78Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice
Jeromin_2008_Biotechnol.Lett_30_925A new irreversible enzyme-aided esterification method in organic solvents
Jett_2008_Chem.Biol.Interact_175_22Cholinesterase research at the National Institutes of Health, USA
Jia_2008_J.Pharmacol.Sci_107_167Blocking histamine H(1) improves learning and mnemonic dysfunction in mice with social isolation plus repeated methamphetamine injection
Jiang_2008_BMC.Biotechnol_8_4Efficient display of active lipase LipB52 with a Pichia pastoris cell surface display system and comparison with the LipB52 displayed on Saccharomyces cerevisiae cell surface
Jiang_2008_Biochemistry_47_3426Identification and characterization of (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase in the menaquinone biosynthesis of Escherichia coli
Jiang_2008_Biomacromolecules_9_3246Lipase-catalyzed synthesis of aliphatic polyesters via copolymerization of lactone, dialkyl diester, and diol
Jiang_2008_Chem.Pharm.Bull.(Tokyo)_56_1286Derivatives of vibralactone from cultures of the basidiomycete Boreostereum vibrans
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Jiang_2008_J.Neurophysiol_99_1988Facilitation of cortico-amygdala synapses by nicotine: activity-dependent modulation of glutamatergic transmission
Jiang_2008_J.Pharmacol.Exp.Ther_326_330Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells
Jimenez-Gomez_2008_Nutr.Metab.Cardiovasc.Dis_18_173The -250G/A polymorphism in the hepatic lipase gene promoter influences the postprandial lipemic response in healthy men
Jimenez_2008_Proc.Natl.Acad.Sci.U.S.A_105_11329Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440
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Jin_2008_FEBS.J_275_2042Changes in acetylcholine receptor function induce shifts in muscle fiber type composition
Jing_2008_Chirality_20_724Determination of absolute configuration of secondary alcohols using lipase-catalyzed kinetic resolutions
Jing_2008_J.Neurochem_104_409GSK3beta mediates the induced expression of synaptic acetylcholinesterase during apoptosis
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Jocken_2008_Histochem.Cell.Biol_129_535Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific
Jocken_2008_Metabolism_57_326Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene
Jocken_2008_Physiol.Behav_94_219Catecholamine-induced lipolysis in adipose tissue and skeletal muscle in obesity
Joerchel_2008_Int.J.Dev.Neurosci_26_301Oligomeric beta-amyloid(1-42) induces the expression of Alzheimer disease-relevant proteins in cholinergic SN56.B5.G4 cells as revealed by proteomic analysis
Jogani_2008_Alzheimer.Dis.Assoc.Disord_22_116Intranasal mucoadhesive microemulsion of tacrine to improve brain targeting
Johansson_2008_PLoS.Genet_4_e1000278An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development/function
John_2008_Anal.Bioanal.Chem_391_97LC-MS-based procedures for monitoring of toxic organophosphorus compounds and verification of pesticide and nerve agent poisoning
John_2008_Eur.J.Med.Res_13_73N-terminal acetylation protects glucagon-like peptide GLP-1-(7-34)-amide from DPP-IV-mediated degradation retaining cAMP- and insulin-releasing capacity
Johnell_2008_Dement.Geriatr.Cogn.Disord_25_54Education and use of dementia drugs: a register-based study of over 600,000 older people
Johnson_2008_Biochem.J_411_507Interaction of acetylcholinesterase with the G4 domain of the laminin alpha1-chain
Johnson_2008_FEBS.J_275_5129Non-enzymatic developmental functions of acetylcholinesterase--the question of redundancy
Johnson_2008_Neuropsychol.Dev.Cogn.B.Aging.Neuropsychol.Cogn_15_129Associative learning over trials activates the hippocampus in healthy elderly but not mild cognitive impairment
Jones_2008_Alzheimers.Dement_4_145The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics
Jones_2008_Anesthesiology_109_816Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine
Jones_2008_Ann.N.Y.Acad.Sci_1129_26Modulation of cortical activation and behavioral arousal by cholinergic and orexinergic systems
Jones_2008_Invert.Neurosci_8_41The cys-loop ligand-gated ion channel gene superfamily of the nematode, Caenorhabditis elegans
Jones_2008_J.Neurosci_28_10422Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Jones_2008_Pest.Manag.Sci_64_12High-throughput allelic discrimination of B and Q biotypes of the whitefly, Bemisia tabaci, using TaqMan allele-selective PCR
Jonkman_2008_Neuropsychopharmacology_33_2131Spontaneous nicotine withdrawal potentiates the effects of stress in rats
Joo_2008_J.Pestic.Sci_33_376Imazamethabenz hydrolysis on oxide surfaces at several pH
Joosen_2008_Neurochem.Res_33_308Percutaneous exposure to VX: clinical signs, effects on brain acetylcholine levels and EEG
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Jose_2008_Comp.Biochem.Physiol.A.Mol.Integr.Physiol_150_347Lipoprotein lipase (LPL) is highly expressed and active in the ovary of European sea bass (Dicentrarchus labrax L.), during gonadal development
Joseph_2008_Biotechnol.Adv_26_457Cold active microbial lipases: some hot issues and recent developments
Joshi_2008_Phytother.Res_22_1581Pharmacological and biological screening of ascorbigen: protection against glucose-induced endothelial cell toxicity
Josif_2008_JAAPA_21_22Diagnosis and treatment of dementia with Lewy bodies
Jun_2008_Chem.Biol.Interact_175_421Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
Jun_2008_Drug.Chem.Toxicol_31_1Potency of novel oximes to reactivate sarin inhibited human cholinesterases
Jun_2008_Eur.J.Med.Chem_43_1889Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors
Jun_2008_J.Chromatogr.Sci_46_316TLC analysis of intermediates arising during the preparation of oxime HI-6 dimethanesulfonate
Jung_2008_Biotechnol.Lett_30_717Improving the expression yield of Candida antarctica lipase B in Escherichia coli by mutagenesis
Jung_2008_Mar.Pollut.Bull_57_599Biomarker responses in caged rockfish (Sebastes schlegeli) from Masan Bay and Haegeumgang, South Korea
Jung_2008_Proteins_71_476Structural basis for the cold adaptation of psychrophilic M37 lipase from Photobacterium lipolyticum
Kabbani_2008_Proteomics_8_4146Proteomics of membrane receptors and signaling
Kadir_2008_Neurobiol.Aging_29_1204PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD
Kadlec_2008_J.Antimicrob.Chemother_62_469Analysis and distribution of class 1 and class 2 integrons and associated gene cassettes among Escherichia coli isolates from swine, horses, cats and dogs collected in the BfT-GermVet monitoring study
Kaduszkiewicz_2008_Evid.Based.Ment.Health_11_113Review: cholinesterase inhibitors and memantine consistently but marginally improve symptoms of dementia
Kahler_2008_Am.J.Med.Genet.B.Neuropsychiatr.Genet_147B_1089Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Kaibori_2008_Hepatogastroenterology_55_2151Risk factors for early death due to recurrence after resection of large hepatocellular carcinomas
Kaizer_2008_Neurochem.Res_33_2294Effect of long-term exposure to aluminum on the acetylcholinesterase activity in the central nervous system and erythrocytes
Kajita_2008_Diabetes.Res.Clin.Pract_81_144Effect of fasting on PPARgamma and AMPK activity in adipocytes
Kakani_2008_Insect.Biochem.Mol.Biol_38_781A small deletion in the olive fly acetylcholinesterase gene associated with high levels of organophosphate resistance
Kalinichev_2008_Behav.Pharmacol_19_71Locomotor reactivity to a novel environment and sensitivity to MK-801 in five strains of mice
Kalonia_2008_Methods.Find.Exp.Clin.Pharmacol_30_529Possible mechanism involved in sleep deprivation-induced memory dysfunction
Kalow_2008_Can.J.Anaesth_55_860The relation of plasma cholinesterases to response to clinical doses of succinylcholine
Kamahori_2008_Anal.Sci_24_1073Enzyme immunoassay using a reusable extended-gate field-effect-transistor sensor with a ferrocenylalkanethiol-modified gold electrode
Kamal_2008_J.Neural.Transm.(Vienna)_115_889Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis
Kamal_2008_Neurochem.Res_33_745Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental Alzheimer therapeutic, dihydrobenzodioxepine cymserine
Kamath_2008_Pestic.Biochem.Physiol_90_58Dimethoate induced biochemical perturbations in rat pancreas and its attenuation by cashew nut skin extract
Kamboj_2008_Cell.Mol.Neurobiol_28_961Mitochondrial oxidative stress and dysfunction in rat brain induced by carbofuran exposure
Kamel_2008_Environ.Health.Perspect_116_943Association of lead exposure with survival in amyotrophic lateral sclerosis
Kammoun_2008_Pancreas_36_302Purification and characterization of the first reptile pancreatic lipase: the turtle
Kanai_2008_J.Clin.Lab.Anal_22_66Liver function tests in patients with bacteremia
Kanai_2008_J.Med.Chem_51_7514Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules
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Kang_2008_J.Biol.Chem_283_2323Induction of GABAergic postsynaptic differentiation by alpha-neurexins
Kang_2008_J.Microbiol.Biotechnol_18_1427Identification of proteins binding to decursinol by chemical proteomics
Kang_2008_J.Microbiol.Biotechnol_18_1445A cold-adapted epoxide hydrolase from a strict marine bacterium, Sphingophyxis alaskensis
Kang_2008_Nature_456_904Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation
Kao_2008_Anal.Chem_80_4065Reagentless pH-stat for microliter fluid specimens
Kar_2008_J.Ind.Microbiol.Biotechnol_35_1053Investigation of the effect of different extracellular factors on the lipase production by Yarrowia lipolityca on the basis of a scale-down approach
Karanth_2008_Regul.Toxicol.Pharmacol_50_200Selective inhibition of butyrylcholinesterase in vivo in horses by the feed-through larvacide Equitrol
Karasova_2008_Int.J.Mol.Sci_9_2243Effect of several new and currently available oxime cholinesterase reactivators on tabun-intoxicated rats
Kariya_2008_Hum.Mol.Genet_17_2552Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
Karra-Chaabouni_2008_Colloids.Surf.B.Biointerfaces_66_168Physical immobilization of Rhizopus oryzae lipase onto cellulose substrate: activity and stability studies
Karvaly_2008_J.Appl.Toxicol_28_21Application of in vivo microdialysis for studying the efficacy of protective preparations against sulfur mustard penetrating the skin
Kasai_2008_J.Pharmacol.Sci_108_40Antidiabetic and hypolipidemic effects of a novel dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, E3030, in db/db mice and beagle dogs
Kasai_2008_Jpn.J.Infect.Dis_61_184PCR-based identification of Culex pipiens complex collected in Japan
Kasana_2008_J.Basic.Microbiol_48_207Isolation and identification of a psychrotrophic Acinetobacter sp. CR9 and characterization of its alkaline lipase
Kasprowicz_2008_Bull.Entomol.Res_98_115Clonal turnover of MACE-carrying peach-potato aphids (Myzus persicae (Sulzer), Homoptera: Aphididae) colonizing Scotland
Kassa_2008_Chem.Biol.Interact_175_425A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats
Kassa_2008_Drug.Chem.Toxicol_31_371A comparison of the therapeutic and reactivating efficacy of newly developed oximes (K117, K127) and currently available oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice
Kassa_2008_J.Enzyme.Inhib.Med.Chem_23_776A comparison of the therapeutic and reactivating efficacy of newly developed bispyridinium compounds (K206, K269) with currently available oximes against tabun in rats and mice
Kassa_2008_Mini.Rev.Med.Chem_8_1134The development of new oximes and the evaluation of their reactivating, therapeutic and neuroprotective efficacy against tabun
Kassa_2008_Toxicology_243_311An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice
Kassam_2008_J.Neurosci_28_8756Developmental excitation of corticothalamic neurons by nicotinic acetylcholine receptors
Kathiresan_2008_N.Engl.J.Med_358_1240Polymorphisms associated with cholesterol and risk of cardiovascular events
Kato_2008_Scand.J.Gastroenterol_43_1018Reduced hepatic expression of adipose tissue triglyceride lipase and CGI-58 may contribute to the development of non-alcoholic fatty liver disease in patients with insulin resistance
Kaur_2008_Brain.Cogn_67_25Effects of green tea extract on learning, memory, behavior and acetylcholinesterase activity in young and old male rats
Kaur_2008_J.Neurosci_28_491Effects of ibotenate and 192IgG-saporin lesions of the nucleus basalis magnocellularis/substantia innominata on spontaneous sleep and wake states and on recovery sleep after sleep deprivation in rats
Kawai_2008_Biochem.Biophys.Res.Commun_366_834Epibatidine binds to four sites on the Torpedo nicotinic acetylcholine receptor
Kawakami_2008_Ecotoxicology_17_221Monitoring of cholinesterase-inhibiting activity in water from the Tone canal, Japan, as a biomarker of ecotoxicity
Kawano_2008_Biol.Pharm.Bull_31_998Alteration of gene expression induced by Silurus asotus lectin in Burkitt's lymphoma cells
Kawashima_2008_J.Pharmacol.Sci_106_167Basic and clinical aspects of non-neuronal acetylcholine: overview of non-neuronal cholinergic systems and their biological significance
Kayrak_2008_Am.J.Health.Syst.Pharm_65_1051Complete atrioventricular block associated with rivastigmine therapy
Keefe_2008_Neuropsychopharmacology_33_1217Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: significant placebo/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial
Kelai_2008_Neuroreport_19_751Nrxn3 upregulation in the globus pallidus of mice developing cocaine addiction
Keller_2008_J.Biomol.Screen_13_468A high-throughput screen for endothelial lipase using HDL as substrate
Kelly_2008_Schizophr.Res_103_161Lack of beneficial galantamine effect for smoking behavior: a double-blind randomized trial in people with schizophrenia
Kempka_2008_Bioprocess.Biosyst.Eng_31_119Response surface method to optimize the production and characterization of lipase from Penicillium verrucosum in solid-state fermentation
Keng_2008_Bioresour.Technol_99_6097Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
Kent_2008_J.Med.Genet_45_519X-linked ichthyosis (steroid sulfatase deficiency) is associated with increased risk of attention deficit hyperactivity disorder, autism and social communication deficits
Kerekes_2008_J.Rheumatol_35_398Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: a multiparametric analysis using imaging techniques and laboratory markers of inflammation and autoimmunity
Kerfelec_2008_Proteins_73_828Computational study of colipase interaction with lipid droplets and bile salt micelles
Kersten_2008_PPAR.Res_2008_132960Peroxisome proliferator activated receptors and lipoprotein metabolism
Keseru_2008_FASEB.J_22_4306Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response
Kewalramani_2008_Am.J.Physiol.Endocrinol.Metab_295_E137Acute dexamethasone-induced increase in cardiac lipoprotein lipase requires activation of both Akt and stress kinases
Key_2008_Environ.Toxicol_23_153Effects of the statin antihyperlipidemic agent simvastatin on grass shrimp, Palaemonetes pugio
Key_2008_J.Environ.Sci.Health.B_43_50Effects of the anti-fouling herbicide Irgarol 1051 on two life stages of the grass shrimp, Palaemonetes pugio
Key_2008_Sci.Total.Environ_399_28Toxicity and physiological effects of brominated flame retardant PBDE-47 on two life stages of grass shrimp, Palaemonetes pugio
Khajamohiddin_2008_Crit.Rev.Microbiol_34_13Biodegradation of aromatic compounds: an overview of meta-fission product hydrolases
Khan_2008_Chem.Biol.Interact_175_231Pharmacological effects of a novel isosorbide-based butyrylcholinesterase inhibitor
Khan_2008_Int.J.Clin.Exp.Med_1_274Adverse effects of pesticides residues on biochemical markers in pakistani tobacco farmers
Khan_2008_J.Clin.Pharm.Ther_33_669Post-operative pain relief following intrathecal injection of acetylcholine esterase inhibitor during lumbar disc surgery: a prospective double blind randomized study
Khot_2008_Pest.Manag.Sci_64_1139A novel assay reveals the blockade of esterases by piperonyl butoxide
Kienesberger_2008_J.Biol.Chem_283_5908Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase
Kilic_2008_Ann.Ophthalmol.(Skokie)_40_22Protective effects of melatonin on oxidative-antioxidative balance and cataract formation in rats
Kim_2008_Antimicrob.Agents.Chemother_52_606Complete DNA sequence and analysis of the transferable multiple-drug resistance plasmids (R Plasmids) from Photobacterium damselae subsp. piscicida isolates collected in Japan and the United States
Kim_2008_Appl.Microbiol.Biotechnol_77_1041Discovery of three novel lipase ( lipA1 , lipA2 , and lipA3) and lipase-specific chaperone ( lipB) genes present in Acinetobacter sp. DYL129
Kim_2008_Arch.Pharm.Res_31_1225A new stilbene glucoside gallate from the roots of Polygonum multiflorum
Kim_2008_Biochemistry_47_9497Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase
Kim_2008_Biotechnol.Lett_30_127Biosynthesis of (R)-phenyl-1,2-ethanediol from racemic styrene oxide by using bacterial and marine fish epoxide hydrolases
Kim_2008_Biotechnol.Lett_30_329A novel biotransformation of 2-formyl-6-naphthoic acid to 2,6-naphthalene dicarboxylic acid by Pseudomonas sp. for the purification of crude 2,6-naphthalene dicarboxylic acid
Kim_2008_Circ.Res_103_252Protein kinase D is a key regulator of cardiomyocyte lipoprotein lipase secretion after diabetes
Kim_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_151_52Pancreatic lipase-related protein (PY-PLRP) highly expressed in the vitellogenic ovary of the scallop, Patinopecten yessoensis
Kim_2008_Diabetes_57_1331Inhibition of dipeptidyl peptidase IV with sitagliptin (MK0431) prolongs islet graft survival in streptozotocin-induced diabetic mice
Kim_2008_Diabetes_57_64Acute diabetes moderates trafficking of cardiac lipoprotein lipase through p38 mitogen-activated protein kinase-dependent actin cytoskeleton organization
Kim_2008_J.Bacteriol_190_3093Complete genome sequence of Leuconostoc citreum KM20
Kim_2008_J.Clin.Invest_118_3075Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice
Kim_2008_J.Med.Chem_51_589Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines
Kim_2008_J.Microbiol_46_100Cloning and characterization of thermostable esterase from Archaeoglobus fulgidus
Kim_2008_J.Neurophysiol_100_1835Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neurons
Kim_2008_Mol.Cell.Neurosci_39_452O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors
Kim_2008_Mol.Endocrinol_22_477Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiter
Kim_2008_Org.Lett_10_1295Highly enantioselective dynamic kinetic resolution of 1,2-diarylethanols by a lipase-ruthenium couple
Kim_2008_Pharmacol.Rev_60_470The role of incretins in glucose homeostasis and diabetes treatment
Kim_2008_Proc.Natl.Acad.Sci.U.S.A_105_9087Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals
Kim_2008_Proteins_70_578The crystal structure of the estA protein, a virulence factor from Streptococcus pneumoniae
Kim_2008_World.J.Gastroenterol_14_2401Is there correlation between pancreatic enzyme and radiological severity in acute pancreatitis?
King_2008_Nature_451_783The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
Kiran_2008_Bioprocess.Biosyst.Eng_31_483Optimization of extracellular psychrophilic alkaline lipase produced by marine Pseudomonas sp. (MSI057)
Kishi_2008_Ann.N.Y.Acad.Sci_1139_70Alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes are not associated with methamphetamine-use disorder in the Japanese population
Kishi_2008_J.Neural.Transm_115_1457Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population
Kiss_2008_J.Inherit.Metab.Dis_31 Suppl 2_S205A Brazilian galactosialidosis patient given renal transplantation: a case report
Kiss_2008_J.Struct.Biol_162_312Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase
Klasson_2008_Mol.Biol.Evol_25_1877Genome evolution of Wolbachia strain wPip from the Culex pipiens group
Kloss_2008_Biosens.Bioelectron_23_1473Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models
Kneip_2008_BMC.Evol.Biol_8_30The cyanobacterial endosymbiont of the unicellular algae Rhopalodia gibba shows reductive genome evolution
Knight_2008_Hum.Mol.Genet_17_3847A duplication at chromosome 11q12.2-11q12.3 is associated with spinocerebellar ataxia type 20
Knol_2008_Eur.J.Nucl.Med.Mol.Imaging_35_598No significant effects of single intravenous, single oral and subchronic oral administration of acetylcholinesterase inhibitors on striatal [123I]FP-CIT binding in rats
Kobayashi_2008_J.Clin.Endocrinol.Metab_93_2877The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets
Kobayashi_2008_J.Med.Food_11_289Inhibitory effect of Myrica bark on lipase activity in mouse plasma and gastrointestinal tract
Kobayashi_2008_Planta.Med_74_1716Constituents of Rhodiola rosea showing inhibitory effect on lipase activity in mouse plasma and alimentary canal
Kocelak_2008_J.Gastroenterol_43_609Long-term effects of lipase inhibition by orlistat on gastric emptying and orocecal transit time of a solid meal
Koch_2008_Biotechnol.Bioeng_99_1028Enzymatic enantioselective C-C-bond formation in microreactors
Kocharyan_2008_J.Cereb.Blood.Flow.Metab_28_221Specific subtypes of cortical GABA interneurons contribute to the neurovascular coupling response to basal forebrain stimulation
Koda_2008_Psychopharmacology.(Berl)_196_293Galantamine and donepezil differently affect isolation rearing-induced deficits of prepulse inhibition in mice
Koehnke_2008_Proc.Natl.Acad.Sci.U.S.A_105_1873Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2
Koehnke_2008_Structure_16_410Crystal structures of beta-neurexin 1 and beta-neurexin 2 ectodomains and dynamics of splice insertion sequence 4
Koga_2008_Diabetes.Res.Clin.Pract_81_258CLD (chronic liver diseases)-HbA1C as a suitable indicator for estimation of mean plasma glucose in patients with chronic liver diseases
Koglin_2008_Nature_454_907Structural basis for the selectivity of the external thioesterase of the surfactin synthetase
Kohn_2008_Genes.Genet.Syst_83_265Decoupled differentiation of gene expression and coding sequence among Drosophila populations
Koitka_2008_Anal.Biochem_381_113Determination of rat serum esterase activities by an HPLC method using S-acetylthiocholine iodide and p-nitrophenyl acetate
Koivisto_2008_Diabetologia_51_1088Discovery of dipeptidyl-peptidase IV--a 40 year journey from bench to patient
Koladiya_2008_BMC.Pharmacol_8_14Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats
Kolarich_2008_Proteomics_8_254Glycoproteomic characterization of butyrylcholinesterase from human plasma
Kondo_2008_Macromol.Biosci_8_533Lipase-catalyzed ring-opening polymerization of molecularly pure cyclic oligomers for use in synthesis and chemical recycling of aliphatic polyesters
Kone_2008_Acta.Crystallogr.B_64_338Hydrogen-bonding properties of galanthamine: an investigation through crystallographic database observations and computational chemistry
Konstantakaki_2008_J.Mol.Graph.Model_26_1333Model of the extracellular domain of the human alpha7 nAChR based on the crystal structure of the mouse alpha1 nAChR extracellular domain
Konstantinidis_2008_ISME.J_2_1052Genomic patterns of recombination, clonal divergence and environment in marine microbial populations
Kopecka_2008_Ecotoxicol.Environ.Saf_70_379Temporal and spatial variations of selected biomarker activities in flounder (Platichthys flesus) collected in the Baltic proper
Korczyn_2008_Alzheimers.Dement_4_371Treatment of advanced Alzheimer's disease with cholinesterase inhibitors
Kosaka_2008_Genome.Res_18_442The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota
Kota_2008_Psychopharmacology.(Berl)_198_201Age-dependent differences in nicotine reward and withdrawal in female mice
Kotani_2008_Chem.Biol.Interact_175_227Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis
Kotur-Stevuljevic_2008_Clin.Biochem_41_1067PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients
Kourist_2008_Chembiochem_9_491Enzymatic synthesis of optically active tertiary alcohols: expanding the biocatalysis toolbox
Kourist_2008_Chembiochem_9_67Understanding promiscuous amidase activity of an esterase from Bacillus subtilis
Kovac_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_294_G88Temporal and spatial dynamics underlying capacitative calcium entry in human colonic smooth muscle
Kovacevic_2008_Biochim.Biophys.Acta_1783_1981The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets
Kovar_2008_Physiol.Res_57_555Lipoprotein lipase activity determined in vivo is lower in carriers of apolipoprotein A-V gene variants 19W and -1131C
Kovarik_2008_Chem.Biol.Interact_175_173Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning
Koyama_2008_Chudoku.Kenkyu_21_145[Kinetics of organophorus pesticides]
Koyano_2008_Hepatol.Res_38_696Common null variant, Arg192Stop, in a G-protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity
Kozaki_2008_Arch.Insect.Biochem.Physiol_67_130Comparison of two acetylcholinesterase gene cDNAs of the lesser mealworm, Alphitobius diaperinus, in insecticide susceptible and resistant strains
Kracun_2008_Br.J.Pharmacol_153_1474Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function
Kram_2008_Plant.Mol.Biol_68_173Identification, cloning and characterization of a GDSL lipase secreted into the nectar of Jacaranda mimosifolia
Kredel_2008_Anaesthesist_57_1172[Cholestasis and liver dysfunction in critical care patients]
Krentz_2008_Drugs_68_2131New drugs for type 2 diabetes mellitus: what is their place in therapy?
Krieger_2008_Chembiochem_9_1146Fluorescent agonists for the Torpedo nicotinic acetylcholine receptor
Krintel_2008_PLoS.One_3_e3756Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates
Kristoff_2008_Chemosphere_72_1333Effects of azinphos-methyl exposure on enzymatic and non-enzymatic antioxidant defenses in Biomphalaria glabrata and Lumbriculus variegatus
Krnjevic_2008_Neuropharmacol_55_319Electrophysiology of cerebral ischemia
Krstic_2008_J.Enzyme.Inhib.Med.Chem_23_562Inhibition of AChE by malathion and some structurally similar compounds
Krzeslak_2008_Appl.Environ.Microbiol_74_1402Lipase expression in Pseudomonas alcaligenes is under the control of a two-component regulatory system
Kuang_2008_Pharmacol.Biochem.Behav_88_213Postischemic administration of Z-Ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats
Kube_2008_BMC.Genomics_9_306The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'
Kube_2008_Environ.Microbiol_10_2211The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic bacterium in the genus Erwinia
Kucukkilinc_2008_Chem.Biol.Interact_175_309Inhibition of electric eel acetylcholinesterase by triarylmethane dyes
Kuhad_2008_Exp.Brain.Res_185_411Effect of sesamol on diabetes-associated cognitive decline in rats
Kuhad_2008_Life.Sci_83_128Lycopene attenuates diabetes-associated cognitive decline in rats
Kumar_2008_Bioorg.Med.Chem_16_5157Effect of novel N-aryl sulfonamide substituted 3-morpholino arecoline derivatives as muscarinic receptor 1 agonists in Alzheimer's dementia models
Kumar_2008_J.Biol.Chem_283_18032Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon
Kumar_2008_J.Enzyme.Inhib.Med.Chem_23_462Synthesis and antimicrobial studies of novel 1-benzhydryl-piperazine sulfonamide and carboxamide derivatives
Kumar_2008_Phytother.Res_22_1563Protective effect of quercetin against ICV colchicine-induced cognitive dysfunctions and oxidative damage in rats
Kumar_2008_World.J.Microbiol.Biotechnol_24_1047Biosurfactant production and hydrocarbon-degradation by halotolerant and thermotolerant Pseudomonas sp.
Kumari_2008_Bioprocess.Biosyst.Eng_31_291Comparative study of thermostability and ester synthesis ability of free and immobilized lipases on cross linked silica gel
Kuntz_2008_Genome.Res_18_1955Multigenome DNA sequence conservation identifies Hox cis-regulatory elements
Kupchik_2008_Proc.Natl.Acad.Sci.U.S.A_105_4435Molecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release
Kuroki_2008_Pancreas_37_203Culture of porcine fetal pancreatic neurons
Kurota_2008_Seishin.Shinkeigaku.Zasshi_110_571[Clinical and pathological findings in dementia with Lewy bodies]
Kurrikoff_2008_Eur.J.Neurosci_27_2147Stress-induced analgesia in mice: evidence for interaction between endocannabinoids and cholecystokinin
Kusumawati_2008_J.Proteome.Res_7_4508Characterization of the secretome of suspension cultures of Medicago species reveals proteins important for defense and development
Kuswandi_2008_Talanta_74_613An optical fiber biosensor for chlorpyrifos using a single sol-gel film containing acetylcholinesterase and bromothymol blue
Kuwahara_2008_Protein.Eng.Des.Sel_21_737Importance of the Ca2+-binding sites in the N-catalytic domain of a family I.3 lipase for activity and stability
Laalou_2008_Anesthesiology_108_888Involvement of the basal cholinergic forebrain in the mediation of general (propofol) anesthesia
Labar_2008_Amino.Acids_34_127A MBP-FAAH fusion protein as a tool to produce human and rat fatty acid amide hydrolase: expression and pharmacological comparison
Lack_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_2Structure of HsaD, a steroid-degrading hydrolase, from Mycobacterium tuberculosis
Lacko_2008_Head.Neck_30_836Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer
Lagarce_2008_Presse.Med_37_435[Jimson Weed poisoning: an antidote is available in France]
Lai_2008_Brain.Res.Bull_77_420Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder
Lai_2008_J.Biol.Chem_283_9318Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase
Laks_2008_Curr.Opin.Psychiatry_21_562Reports in pharmacological treatments in geriatric psychiatry: is there anything new or just adding to old evidence?
Lakshmi_2008_Singapore.Med.J_49_561Serum cholinesterases in Down syndrome children before and after nutritional supplementation
Lalli_2008_Expert.Rev.Neurother_8_1181Rivastigmine in Parkinson's disease dementia
Lam_2008_Neurosci.Lett_438_90Effect of cholinergic denervation on hepatic fibrosis induced by carbon tetrachloride in rats
Lambeir_2008_Biochem.Pharmacol_76_1637DPP4 inhibitors for diabetes--what next?
Lamotte d'Incamps_2008_J.Neurosci_28_14121Four excitatory postsynaptic ionotropic receptors coactivated at the motoneuron-Renshaw cell synapse
Lampidonis_2008_Gene_416_30Cloning and functional characterization of the ovine Hormone Sensitive Lipase (HSL) full-length cDNAs: an integrated approach
Lampidonis_2008_Gene_427_65Cloning and functional characterization of the 5' regulatory region of ovine Hormone Sensitive Lipase (HSL) gene
Landmark_2008_Tidsskr.Nor.Laegeforen_128_294[Cholinesterase inhibitors in the treatment of dementia--are they useful in clinical practice?]
Lane_2008_Pharmacogenet.Genomics_18_289Synergistic effect of apolipoprotein E epsilon4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease
Langkilde_2008_J.Agric.Food.Chem_56_8753Acute toxicity of high doses of the glycoalkaloids, alpha-solanine and alpha-chaconine, in the Syrian Golden hamster
Lannfelt_2008_Lancet.Neurol_7_779Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial
Lansdell_2008_J.Neurochem_105_1573Host-cell specific effects of the nicotinic acetylcholine receptor chaperone RIC-3 revealed by a comparison of human and Drosophila RIC-3 homologues
Lape_2008_Nature_454_722On the nature of partial agonism in the nicotinic receptor superfamily
Lapez-Soler_2008_Pest.Manag.Sci_64_1258Esterase isoenzymes and insecticide resistance in Frankliniella occidentalis populations from the south-east region of Spain
Lapidus_2008_Chem.Biol.Interact_171_236Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity
Larsen_2008_Protein.Expr.Purif_62_90Expression of Candida antarctica lipase B in Pichia pastoris and various Escherichia coli systems
Larsson_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_294_G165Pharmacological analysis of components of the change in transmural potential difference evoked by distension of rat proximal small intestine in vivo
Lasram_2008_Pestic.Biochem.Physiol_92_114Effect of short-time malathion administration on glucose homeostasis in Wistar rat
Lassalle_2008_Bioprocess.Biosyst.Eng_31_499Lipase-catalyzed copolymerization of lactic and glycolic acid with potential as drug delivery devices
Lassiter_2008_Environ.Health.Perspect_116_1456Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood
Latere_2008_Pharmazie_63_235Spontaneously self-assembled micelles from poly(ethylene glycol)-b-poly(epsilon-caprolactone-co-trimethylene carbonate) for drug solubilization
Lau_2008_Eur.J.Pharmacol_578_137The cannabinoid CB1 receptor is expressed on serotonergic and dopaminergic neurons
Lau_2008_Mol.Cell.Neurosci_39_429Myocyte enhancer factor 2 mediates acetylcholine-induced expression of acetylcholinesterase-associated collagen ColQ in cultured myotubes
Lau_2008_Mol.Pharmacol_74_1392Muscarinic modulation of synaptic transmission via endocannabinoid signalling in the rat midbrain periaqueductal gray
Lawson-Yuen_2008_Eur.J.Hum.Genet_16_614Familial deletion within NLGN4 associated with autism and Tourette syndrome
Lazarus_2008_Inflamm.Res_57_18An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis
Le Foll_2008_Addict.Biol_13_239Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies
Leduc_2008_Neurodegener.Dis_5_225Polymorphisms at the paraoxonase 1 L55M and Q192R loci affect the pathophysiology of Alzheimer's disease: emphasis on the cholinergic system and beta-amyloid levels
Lee_2008_Arch.Neurol_65_1518Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci
Lee_2008_BMC.Genomics_9_247Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
Lee_2008_Clin.Chim.Acta_387_172Compound heterozygosity of novel missense mutations (Ser45 --> Gly, Cys278 --> Arg) in the lipoprotein lipase gene in a newborn Korean infant
Lee_2008_Eur.J.Pharmacol_589_306Pharmacokinetic, pharmacodynamic, and efficacy profiles of alogliptin, a novel inhibitor of dipeptidyl peptidase-4, in rats, dogs, and monkeys
Lee_2008_J.Bacteriol_190_1638A common virulence plasmid in biotype 2 Vibrio vulnificus and its dissemination aided by a conjugal plasmid
Lee_2008_J.Bacteriol_190_7491The complete genome sequence of Thermococcus onnurineus NA1 reveals a mixed heterotrophic and carboxydotrophic metabolism
Lee_2008_J.Biotechnol_133_486Lipase-catalyzed synthesis of glucose fatty acid ester using ionic liquids mixtures
Lee_2008_J.Clin.Epidemiol_61_1152Published randomized controlled trials of drug therapy for dementia often lack complete data on harm
Lee_2008_J.Clin.Invest_118_2950The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone
Lee_2008_J.Endod_34_433Terrein reduces pulpal inflammation in human dental pulp cells
Lee_2008_J.Gen.Physiol_132_265Nicotinic receptor interloop proline anchors beta1-beta2 and Cys loops in coupling agonist binding to channel gating
Lee_2008_J.Gene.Med_10_260Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats
Lee_2008_J.Microbiol.Biotechnol_18_465Development of magnetically separable immobilized lipase by using cellulose derivatives and their application in enantioselective esterification of ibuprofen
Lee_2008_J.Nucl.Med_49_2006Changes in cerebral glucose metabolism in patients with Parkinson disease with dementia after cholinesterase inhibitor therapy
Lee_2008_Mol.Biol.Cell_19_150The function of mitochondria in presynaptic development at the neuromuscular junction
Lee_2008_Pest.Manag.Sci_64_544Host perception and signal transduction studies in wild-type Blumeria graminis f. sp. hordei and a quinoxyfen-resistant mutant implicate quinoxyfen in the inhibition of serine esterase activity
Lee_2008_Transplant.Proc_40_1353Genetic variations in soluble epoxide hydrolase and graft function in kidney transplantation
Lefevre_2008_Clin.Pharmacol.Ther_83_106Pharmacokinetics and pharmacodynamics of the novel daily rivastigmine transdermal patch compared with twice-daily capsules in Alzheimer's disease patients
Legler_2008_Biochemistry_47_9592Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase
Lejon_2008_J.Mol.Biol_377_935The last step in cephalosporin C formation revealed: crystal structures of deacetylcephalosporin C acetyltransferase from Acremonium chrysogenum in complexes with reaction intermediates
Lekhal_2008_Lipids_43_507Increased postprandial triglyceride-rich lipoprotein levels in elderly survivors of myocardial infarction
Lekhal_2008_Nutr.Metab.Cardiovasc.Dis_18_700Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction
Lemstra_2008_Dement.Geriatr.Cogn.Disord_25_60Identification of responders to rivastigmine: a prospective cohort study
Lendvai_2008_Physiol.Rev_88_333Nonsynaptic chemical transmission through nicotinic acetylcholine receptors
Leon_2008_Bioorg.Med.Chem_16_7759New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties
Leonetti_2008_Bioorg.Med.Chem_16_7450Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors
Leoni_2008_Toxicol.Appl.Pharmacol_233_343The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion
Leroy_2008_Biofouling_24_11Effects of commercial enzymes on the adhesion of a marine biofilm-forming bacterium
Letek_2008_J.Bacteriol_190_5797Evolution of the Rhodococcus equi vap pathogenicity island seen through comparison of host-associated vapA and vapB virulence plasmids
Leticia_2008_Ecotoxicol.Environ.Saf_71_787Determination of esterase activity and characterization of cholinesterases in the reef fish Haemulon plumieri
Leung_2008_Neuron_58_884DAG lipase activity is necessary for TRP channel regulation in Drosophila photoreceptors
Levano_2008_Anesth.Analg_106_147Rapid and accurate detection of atypical and Kalow variants in the butyrylcholinesterase gene using denaturing high performance liquid chromatography
Levasseur_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_862_140Enantiospecific gas chromatographic-mass spectrometric analysis of urinary methylphenidate: implications for phenotyping
Levi_2008_Pharmacol.Biochem.Behav_88_438Discrimination and avoidance learning in adult mice following developmental exposure to diisopropylfluorophosphate
Leyhe_2008_Eur.Arch.Psychiatry.Clin.Neurosci_258_124Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease
Li_2008_Ann.Epidemiol_18_760Association of the lipoprotein lipase gene T+495G polymorphism with central obesity and serum lipids in a twin study
Li_2008_Biochem.J_411_425Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers
Li_2008_Chem.Biol.Interact_175_68Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase
Li_2008_Chem.Biol.Interact_175_88The butyrylcholinesterase knockout mouse is obese on a high-fat diet
Li_2008_Chem.Biol_15_118Nonribosomal biosynthesis of fusaricidins by Paenibacillus polymyxa PKB1 involves direct activation of a D-amino acid
Li_2008_Chem.Res.Toxicol_21_421Binding and hydrolysis of soman by human serum albumin
Li_2008_Chembiochem_9_71Catalytic promiscuity in the alpha/beta-hydrolase superfamily: hydroxamic acid formation, C--C bond formation, ester and thioester hydrolysis in the C--C hydrolase family
Li_2008_Chemosphere_70_1796Effects of nonionic and ionic surfactants on survival, oxidative stress, and cholinesterase activity of planarian
Li_2008_Cochrane.Database.Syst.Rev__CD005592Huperzine A for Alzheimer's disease
Li_2008_Ecotoxicol.Environ.Saf_71_781Effects of nonylphenol on cholinesterase and carboxylesterase activities in male guppies (Poecilia reticulata)
Li_2008_Fish.Physiol.Biochem_34_209Acute toxicity of the pesticide methomyl on the topmouth gudgeon (Pseudorasbora parva): mortality and effects on four biomarkers
Li_2008_Front.Biosci_13_3480Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension
Li_2008_Hepatobiliary.Pancreat.Dis.Int_7_40Prognostic factors for chronic severe hepatitis and construction of a prognostic model
Li_2008_J.Bacteriol_190_251Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner
Li_2008_J.Biol.Chem_283_28607Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis
Li_2008_J.Comp.Neurol_506_733Neuroendocrine secretory protein 55 (NESP55) in the spinal cord of rat: an immunocytochemical study
Li_2008_J.Environ.Sci.Health.B_43_638Toxic effects of chlorpromazine on Carassius auratus and its oxidative stress
Li_2008_J.Pharmacol.Exp.Ther_324_1146The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency
Li_2008_Lipids_43_301Molecular mechanism of age-specific hepatic lipid accumulation in PPARalpha (+/-):LDLR (+/-) mice, an obese mouse model
Li_2008_Microb.Cell.Fact_7_38Molecular cloning and characterization of a novel pyrethroid-hydrolyzing esterase originating from the Metagenome
Li_2008_Mol.Neurobiol_37_164Acetylcholine receptor gamma-subunits mRNA isoforms expressed in denervated rat muscle
Li_2008_Neuropsychopharmacology_33_2820Nicotinic acetylcholine receptors and modulation of learning in 4- and 27-month-old rabbits
Li_2008_Zhong.Xi.Yi.Jie.He.Xue.Bao_6_25[A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment]
Liang_2008_Appl.Microbiol.Biotechnol_80_183Phthalates biodegradation in the environment
Liang_2008_Bioorg.Med.Chem.Lett_18_3706Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design
Liang_2008_Brain.Res_1231_6Effect of a novel neurotensin analog, NT69L, on nicotine-induced alterations in monoamine levels in rat brain
Liang_2008_Neurobiol.Learn.Mem_90_138Nicotinic modulation of tone-evoked responses in auditory cortex reflects the strength of prior auditory learning
Liang_2008_Org.Lett_10_193Highly efficient asymmetric synthesis of fluvirucinine A1 via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)-lipase-catalyzed acetylation tandem process
Liao_2008_Mol.Plant.Microbe.Interact_21_469Genetic dissection defines the roles of elsinochrome Phytotoxin for fungal pathogenesis and conidiation of the citrus pathogen Elsino fawcettii
Liapi_2008_Metab.Brain.Dis_23_289Equilibrated diet restores the effects of early age choline-deficient feeding on rat brain antioxidant status and enzyme activities: the role of homocysteine, L-phenylalanine and L-alanine
Lienqueo_2008_Biotechnol.Lett_30_1353Influence of tryptophan tags on the purification of cutinase, secreted by a recombinant Saccharomyces cerevisiae, using cationic expanded bed adsorption and hydrophobic interaction chromatography
Liepelt_2008_Nervenarzt_79_36[Treatment for dementia in parkinsonian syndromes. Efficacy of cholinesterase inhibitors]
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Lim_2008_Int.J.Syst.Evol.Microbiol_58_565Burkholderia sediminicola sp. nov., isolated from freshwater sediment
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Lin_2008_J.Neurosci_28_3333The role of nerve- versus muscle-derived factors in mammalian neuromuscular junction formation
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Liperoti_2008_Curr.Neuropharmacol_6_117Antipsychotics for the treatment of behavioral and psychological symptoms of dementia (BPSD)
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Liu_2008_Biotechnol.Lett_30_497Lipase-catalyzed selective synthesis of monolauroyl maltose using continuous stirred tank reactor
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Liu_2008_Development_135_1957Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning
Liu_2008_Endocrinology_149_711Estrogen-enhanced gene expression of lipoprotein lipase in heart is antagonized by progesterone
Liu_2008_Gen.Comp.Endocrinol_156_164Overexpression of Drosophila juvenile hormone esterase binding protein results in anti-JH effects and reduced pheromone abundance
Liu_2008_Gene_420_57A rice serine carboxypeptidase-like gene OsBISCPL1 is involved in regulation of defense responses against biotic and oxidative stress
Liu_2008_J.Cell.Physiol_216_91L- and N-current but not M-current inhibition by M1 muscarinic receptors requires DAG lipase activity
Liu_2008_J.Clin.Endocrinol.Metab_93_1980Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men
Liu_2008_J.Endocrinol_196_57Glucagon-like peptide-1 attenuates tumour necrosis factor-alpha-mediated induction of plasminogen [corrected] activator inhibitor-1 expression
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Liu_2008_J.Zhejiang.Univ.Sci.B_9_44Effects of over-expressing resistin on glucose and lipid metabolism in mice
Liu_2008_Mol.Cell.Neurosci_38_236EphB receptors co-distribute with a nicotinic receptor subtype and regulate nicotinic downstream signaling in neurons
Liu_2008_Neuropharmacol_54_1Multiple pathways involved in the biosynthesis of anandamide
Liu_2008_Neuropharmacol_54_1086Inhibition of NMDA-gated ion channels by bis(7)-tacrine: whole-cell and single-channel studies
Liu_2008_Neurosci.Lett_434_195Release of acetylcholine by syringin, an active principle of Eleutherococcus senticosus, to raise insulin secretion in Wistar rats
Liu_2008_Pestic.Biochem.Physiol_91_45Effects of temperature on fitness costs, insecticide susceptibility and heat shock protein in insecticide-resistant and -susceptible Plutella xylostella
Liu_2008_Phytomedicine_15_1140Saponins (Ginsenosides) from stems and leaves of Panax quinquefolium prevented high-fat diet-induced obesity in mice
Liu_2008_Psychopharmacology.(Berl)_196_365Cue-induced reinstatement of nicotine-seeking behavior in rats: effect of bupropion, persistence over repeated tests, and its dependence on training dose
Liu_2008_Ultrason.Sonochem_15_402The effect of ultrasound on lipase-catalyzed hydrolysis of soy oil in solvent-free system
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London_2008_Biol.Cybern_99_393Predicting the synaptic information efficacy in cortical layer 5 pyramidal neurons using a minimal integrate-and-fire model
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Lopez-Raez_2008_New.Phytol_178_863Tomato strigolactones are derived from carotenoids and their biosynthesis is promoted by phosphate starvation
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Lu_2008_J.Lipid.Res_49_2582Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations
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Luic_2008_J.Phys.Chem.B_112_4876Combined X-ray diffraction and QM/MM study of the Burkholderia cepacia lipase-catalyzed secondary alcohol esterification
Lukaszewicz-Hussain_2008_Food.Chem.Toxicol_46_82Subchronic intoxication with chlorfenvinphos, an organophosphate insecticide, affects rat brain antioxidative enzymes and glutathione level
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Luttge_2008_J.Exp.Bot_59_1503Clusia: Holy Grail and enigma
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Ma_2008_Biol.Pharm.Bull_31_1316Expression of NDRG2 in clear cell renal cell carcinoma
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Mach_2008_J.Appl.Toxicol_28_132Delayed behavioral and endocrine effects of sarin and stress exposure in mice
Machida_2008_DNA.Res_15_173Genomics of Aspergillus oryzae: learning from the history of Koji mold and exploration of its future
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Machreki-Ajmi_2008_Ecotoxicology_17_1The effect of in situ cadmium contamination on some biomarkers in Cerastoderma glaucum
Machreki-Ajmi_2008_Ecotoxicology_17_802Assessment of sediment/water contamination by in vivo transplantation of the cockles Cerastoderma glaucum from a non contaminated to a contaminated area by cadmium
Mackert_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_33Identification of a juvenile hormone esterase-like gene in the honey bee, Apis mellifera L.--expression analysis and functional assays
Madsbad_2008_Curr.Opin.Clin.Nutr.Metab.Care_11_491Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials
Maeck_2008_Int.J.Geriatr.Psychiatry_23_415Primary care physicians' attitudes related to cognition enhancers in early dementia: a representative eight-year follow-up study in Lower Saxony, Germany
Magana_2008_Insect.Biochem.Mol.Biol_38_756Mechanisms of resistance to malathion in the medfly Ceratitis capitata
Magrioti_2008_Bioorg.Med.Chem.Lett_18_5424A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity
Mahadeva_2008_Semin.Neurol_28_212Autoimmune disorders of neuromuscular transmission
Mahanta_2008_Bioresour.Technol_99_1729Production of protease and lipase by solvent tolerant Pseudomonas aeruginosa PseA in solid-state fermentation using Jatropha curcas seed cake as substrate
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Mahjoubi-Samet_2008_Pestic.Biochem.Physiol_91_96Nephrotoxicity induced by dimethoate in adult rats and their suckling pups
Mahmoud_2008_J.Reprod.Immunol_77_186Butyrylcholinesterase activity and lymphocyte subpopulations in peripheral blood of Kuwaiti women experiencing recurrent spontaneous abortion
Maia_2008_Planta.Med_74_1457Acylphenols from Myristica crassa as new acetylcholinesterase inhibitors
Maier_2008_Science_321_1315The crystal structure of a mammalian fatty acid synthase
Maingrette_2008_J.Lipid.Res_49_1926C-reactive protein enhances macrophage lipoprotein lipase expression
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Maire_2008_Am.J.Gastroenterol_103_2871Intraductal papillary mucinous neoplasms of the pancreas: performance of pancreatic fluid analysis for positive diagnosis and the prediction of malignancy
Maiti_2008_Behav.Brain.Res_189_233Hypobaric hypoxia induces dendritic plasticity in cortical and hippocampal pyramidal neurons in rat brain
Maiti_2008_J.Chem.Neuroanat_36_227High altitude memory impairment is due to neuronal apoptosis in hippocampus, cortex and striatum
Maitra_2008_Ecotoxicol.Environ.Saf_71_236Testicular functions and serum titers of LH and testosterone in methyl parathion-fed roseringed parakeets
Maity_2008_J.Org.Chem_73_5629Efficient and selective enzymatic acylation reaction: separation of furanosyl and pyranosyl nucleosides
Makhaeva_2008_Dokl.Biochem.Biophys_423_352Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols
Malouf_2008_Cochrane.Database.Syst.Rev__CD004514Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people
Man_2008_J.Alzheimers.Dis_14_209Systematic review on the efficacy and safety of herbal medicines for Alzheimer's disease
Mancini_2008_Vasc.Health.Risk.Manag_4_325Orlistat in the prevention of diabetes in the obese patient
Mandrich_2008_Proteins_71_1721Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius
Manickam_2008_J.Appl.Microbiol_104_952Isolation of hexachlorocyclohexane-degrading Sphingomonas sp. by dehalogenase assay and characterization of genes involved in gamma-HCH degradation
Mann_2008_Neuropharmacol_55_1147Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
Mans_2008_Insect.Biochem.Mol.Biol_38_42Comparative sialomics between hard and soft ticks: implications for the evolution of blood-feeding behavior
Mao_2008_J.Neurochem_104_446The alpha4beta2alpha5 nicotinic cholinergic receptor in rat brain is resistant to up-regulation by nicotine in vivo
Marchegiani_2008_Rejuvenation.Res_11_113Paraoxonase 1: genetics and activities during aging
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Margaritopoulos_2008_Pest.Manag.Sci_64_900Efficacy of the pyrethroid alpha-cypermethrin against Bactrocera oleae populations from Greece, and improved diagnostic for an iAChE mutation
Marighetto_2008_Psychopharmacology.(Berl)_197_499Comparative effects of the alpha7 nicotinic partial agonist, S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice
Marino_2008_Diabetes.Self.Manag_25_60, 62DPP-4 inhibitors. A new class of drugs for type 2 diabetes
Markou_2008_Philos.Trans.R.Soc.Lond.B.Biol.Sci_363_3159Review. Neurobiology of nicotine dependence
Marsillach_2008_Free.Radic.Biol.Med_45_146Immunohistochemical analysis of paraoxonases-1, 2, and 3 expression in normal mouse tissues
Martens_2008_Curr.Mol.Med_8_544Multi-system disorder syndromes associated with cystinuria type I
Martin-Cuadrado_2008_ISME.J_2_865Hindsight in the relative abundance, metabolic potential and genome dynamics of uncultivated marine archaea from comparative metagenomic analyses of bathypelagic plankton of different oceanic regions
Martin_2008_Diabetes.Educ_34 Suppl 3_66SBeyond glycemic control: the effects of incretin hormones in type 2 diabetes
Martin_2008_Nature_452_88The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis
Martin_2008_Neuromuscul.Disord_18_942Muscular dystrophy associated with alpha-dystroglycan deficiency in Sphynx and Devon Rex cats
Martinez-Lopez_2008_Clin.Sci.(Lond)_115_245Cancer-associated differences in acetylcholinesterase activity in bronchial aspirates from patients with lung cancer
Martinez_2008_Nat.Biotechnol_26_553Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina)
Maruta_2008_J.Neurochem_105_401Lysophosphatidic acid-LPA1 receptor-Rho-Rho kinase-induced up-regulation of Nav1.7 sodium channel mRNA and protein in adrenal chromaffin cells: enhancement of 22Na+ influx, 45Ca2+ influx and catecholamine secretion
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Masilamoni_2008_Free.Radic.Res_42_661The neuroprotective role of melatonin against amyloid beta peptide injected mice
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Massa_2008_Ecotoxicol.Environ.Saf_71_230Role of acetylcholinesterase and glutathione S-transferase following exposure to nicosulfuron and diazinon in Helicoverpa zea
Masson_2008_Chem.Biol.Interact_175_273A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters
Masson_2008_FEBS.J_275_2617Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters
Massoud_2008_Can.J.Neurol.Sci_35_508Drug utilization review of cholinesterase inhibitors in Quebec
Massoulie_2008_Chem.Biol.Interact_175_30Old and new questions about cholinesterases
Mastrantonio_2008_J.Mol.Model_14_813Interpretation of the mechanism of acetylcholinesterase inhibition ability by organophosphorus compounds through a new conformational descriptor. an experimental and theoretical study
Matejkova_2008_BMC.Microbiol_8_76Complete genome sequence of Treponema pallidum ssp. pallidum strain SS14 determined with oligonucleotide arrays
Mateo_2008_Eur.J.Neurol_15_219Gene-gene interaction between 14-3-3 zeta and butyrylcholinesterase modulates Alzheimer's disease risk
Mateos_2008_J.Agric.Food.Chem_56_10960New lipophilic tyrosyl esters. Comparative antioxidant evaluation with hydroxytyrosyl esters
Mathee_2008_Proc.Natl.Acad.Sci.U.S.A_105_3100Dynamics of Pseudomonas aeruginosa genome evolution
Mathurin_2008_Acta.Gastroenterol.Latinoam_38_116[Renal failure in patients with cirrhosis and ascites: incidence, etiology and predictive factors]
Matsumura_2008_Proteins_70_592Novel cation-pi interaction revealed by crystal structure of thermoalkalophilic lipase
Matsunaga_2008_J.Biol.Chem_283_28835Mycolyltransferase-mediated glycolipid exchange in Mycobacteria
Matsuo_2008_J.Oleo.Sci_57_375Continuous synthesis of glyceryl ferulate using immobilized Candida antarctica lipase
Matsuyama-Yokono_2008_Biochem.Pharmacol_76_98ASP8497 is a novel selective and competitive dipeptidyl peptidase-IV inhibitor with antihyperglycemic activity
Mattes_2008_Appl.Environ.Microbiol_74_6405The genome of Polaromonas sp. strain JS666: insights into the evolution of a hydrocarbon- and xenobiotic-degrading bacterium, and features of relevance to biotechnology
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Maxwell_2008_Toxicol.Appl.Pharmacol_231_157A structure-activity analysis of the variation in oxime efficacy against nerve agents
Mayumi_2008_Appl.Microbiol.Biotechnol_79_743Identification and characterization of novel poly(DL-lactic acid) depolymerases from metagenome
Mazor_2008_Mol.Pharmacol_74_755Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase
Mazumdar_2008_Biochim.Biophys.Acta_1784_351X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579
McCarney_2008_Int.J.Geriatr.Psychiatry_23_1222Ginkgo biloba for mild to moderate dementia in a community setting: a pragmatic, randomised, parallel-group, double-blind, placebo-controlled trial
McDermott_2008_PLoS.ONE_3_E2442Estimation of isolation times of the island species in the Drosophila simulans complex from multilocus DNA sequence data
McEwen_2008_Mol.Biol.Cell_19_3836UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin
McGeown_2008_Neuropsychiatr.Dis.Treat_4_465Prolonged cholinergic enrichment influences regional cortical activation in early Alzheimer's disease
McGuinness_2008_Front.Biosci_13_2435Dipeptidyl peptidase IV (DPPIV), a candidate tumor suppressor gene in melanomas is silenced by promoter methylation
McIntosh_2008_Front.Biosci_13_1753Dipeptidyl peptidase IV inhibitors and diabetes therapy
McNamara_2008_J.Emerg.Med_35_167Acute colonic pseudo-obstruction: rapid correction with neostigmine in the emergency department
McShan_2008_J.Bacteriol_190_7773Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes
Mehrani_2008_Toxicol.In.Vitro_22_1257Changes in mRNA and protein levels of nicotinic acetylcholine receptors in Diazoxon exposed pC12 cells
Meier-Ruge_2008_Pathobiology_75_233Current concepts of enzyme histochemistry in modern pathology
Meikle_2008_Biochem.J_411_71Effect of lysosomal storage on bis(monoacylglycero)phosphate
Meilanov_2008_Biofizika_53_613[Temperature dependence of the acetylcholinesterase activity in synaptic membranes of the rat brain]
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Melzer_2008_J.Ind.Microbiol.Biotechnol_35_485Production of epoxide hydrolases in batch fermentations of Botryosphaeria rhodina
Mendelsohn_2008_Neuron_57_159Mesmerizing memories: brain substrates of episodic memory suppression in posthypnotic amnesia
Menuz_2008_J.Neurosci_28_8740TARP redundancy is critical for maintaining AMPA receptor function
Merritt_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_474Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function
Merritt_2008_J.Pharmacol.Exp.Ther_326_483The endogenous cannabinoid system modulates nicotine reward and dependence
Metzler_2008_Protein.Sci_17_240Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation
Meyer-Losic_2008_Clin.Cancer.Res_14_2145DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies
Micaelo_2008_J.Phys.Chem.B_112_2566Protein structure and dynamics in ionic liquids. Insights from molecular dynamics simulation studies
Michael_2008_Curr.Dir.Autoimmun_10_333Novel mechanism for therapeutic action of IVIg in autoimmune blistering dermatoses
Michalski_2008_Int.J.Cancer_122_742Cannabinoids in pancreatic cancer: correlation with survival and pain
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Mihaylova_2008_Brain_131_747Clinical and molecular genetic findings in COLQ-mutant congenital myasthenic syndromes
Mikami_2008_Pharmacogenet.Genomics_18_213Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population
Militante_2008_Mol.Pharmacol_74_764Activation and block of the adult muscle-type nicotinic receptor by physostigmine: single-channel studies
Millar_2008_Br.J.Pharmacol_153 Suppl 1_S177RIC-3: a nicotinic acetylcholine receptor chaperone
Millar_2008_Mol.Membr.Biol_25_279Assembly and trafficking of nicotinic acetylcholine receptors (Review)
Miller_2008_Bioorg.Med.Chem.Lett_18_5443Synthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen
Miller_2008_Foodborne.Pathog.Dis_5_371The complete genome sequence and analysis of the human pathogen Campylobacter lari
Miller_2008_J.Med.Entomol_45_905Differential response to diazinon and coumaphos in a strain of Boophilus microplus (Acari: Ixodidae) collected in Mexico
Miller_2008_J.Nutr_138_927Carboxyl ester lipase from either mother's milk or the pancreas is required for efficient dietary triglyceride digestion in suckling mice
Minami_2008_J.Toxicol.Sci_33_405Regulation of insulin-like growth factor binding protein-1 and lipoprotein lipase by the aryl hydrocarbon receptor
Mineur_2008_Biochem.Pharmacol_75_323Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
Mingrone_2008_Obesity.(Silver.Spring)_16_1831Prolactin and insulin ultradian secretion and adipose tissue lipoprotein lipase expression in severely obese women after bariatric surgery
Miniaci_2008_Neuron_59_1024Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia
Mir_2008_Lasers.Med.Sci_23_19Photodynamic inhibition of acetylcholinesterase after two-photon excitation of copper tetrasulfophthalocyanine
Mirajkar_2008_Biochem.Pharmacol_76_1047In vitro sensitivity of cholinesterases and [3H]oxotremorine-M binding in heart and brain of adult and aging rats to organophosphorus anticholinesterases
Mirdamadi_2008_Br.J.Clin.Pharmacol_66_366The human paraoxonase-1 phenotype modifies the effect of statins on paraoxonase activity and lipid parameters
Miron_2008_Chemosphere_74_1Biochemical effects of clomazone herbicide on piava (Leporinus obtusidens)
Misawa_2008_Eur.J.Neurosci_27_3109Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice
Mishra_2008_Infect.Immun_76_127Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY
Misiunas_2008_Biophys.Chem_134_144Thermomyces lanuginosus lipase in the liquid-crystalline phases of aqueous phytantriol: X-ray diffraction and vibrational spectroscopic studies
Mistry_2008_Br.J.Clin.Pharmacol_66_36Sitagliptin, an dipeptidyl peptidase-4 inhibitor, does not alter the pharmacokinetics of the sulphonylurea, glyburide, in healthy subjects
Mistry_2008_J.Clin.Pharmacol_48_592Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood pressure in nondiabetic patients with mild to moderate hypertension
Mitchell_2008_Biochim.Biophys.Acta_1784_705An analytical method for determining relative specificities for sequential reactions catalyzed by the same enzyme: general formulation
Mitchell_2008_J.Biotechnol_133_343An analytical method for determining relative specificities for sequential reactions catalyzed by the same enzyme: application to the hydrolysis of triacylglycerols by lipases
Mitsunaga_2008_Pancreas_36_241Low serum level of cholinesterase at recurrence of pancreatic cancer is a poor prognostic factor and relates to systemic disorder and nerve plexus invasion
Mittelman_2008_Am.J.Geriatr.Psychiatry_16_893A three-country randomized controlled trial of a psychosocial intervention for caregivers combined with pharmacological treatment for patients with Alzheimer disease: effects on caregiver depression
Miyamoto_2008_Mol.Plant.Microbe.Interact_21_1591Functional analysis of a multicopy host-selective ACT-toxin biosynthesis gene in the tangerine pathotype of Alternaria alternata using RNA silencing
Miyamoto_2008_Rinsho.Byori_56_761[Relationship between glycated albumin (GA) and glycated hemoglobin (A1c) in 255 patients with liver diseases using cross-sectional laboratory data]
Miyashita_2008_Br.J.Nutr_99_1076Moderate exercise reduces serum triacylglycerol concentrations but does not affect pre-heparin lipoprotein lipase concentrations after a moderate-fat meal in young men
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Miyauchi_2008_J.Biosci.Bioeng_105_628Isolation of dibenzofuran-degrading bacterium, Nocardioides sp. DF412, and characterization of its dibenzofuran degradation genes
Miyawaki_2008_J.Biosci.Bioeng_105_61Lipase-catalyzed butanolysis of triolein in ionic liquid and selective extraction of product using supercritical carbon dioxide
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Miyoshi_2008_J.Cell.Biochem_105_1430Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes
Moaddel_2008_Anal.Chem_80_48Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type
Mochida_2008_Environ.Toxicol.Chem_27_367Early life-stage toxicity test for copper pyrithione and induction of skeletal anomaly in a teleost, the mummichog (Fundulus heteroclitus)
Modrego_2008_Am.J.Alzheimers.Dis.Other.Demen_23_286The clinical significance of plasmatic amyloid A{beta}-40 peptide levels in Alzheimer's disease patients treated with galantamine
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Moral-Naranjo_2008_Chem.Biol.Interact_175_312Targeting of acetylcholinesterase to lipid rafts of muscle
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Moreno_2008_Toxicol.Lett_176_162Long-term monoamine changes in the striatum and nucleus accumbens after acute chlorpyrifos exposure
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Moriarty_2008_J.Med.Chem_51_7991Discovery of a true aspirin prodrug
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Moritoh_2008_Eur.J.Pharmacol_588_325Chronic administration of alogliptin, a novel, potent, and highly selective dipeptidyl peptidase-4 inhibitor, improves glycemic control and beta-cell function in obese diabetic ob/ob mice
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Moroni_2008_J.Neurosci_28_6884Non-agonist-binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the alpha4beta2 nicotinic receptor: an alpha4-alpha4 interface is required for Zn2+ potentiation
Morytko_2008_Bioorg.Med.Chem.Lett_18_2093Synthesis and in vitro activity of N'-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists
Mossello_2008_Dement.Geriatr.Cogn.Disord_25_372Is antidepressant treatment associated with reduced cognitive decline in Alzheimer's disease?
Mosser_2008_J.Mol.Signal_3_20Differential role of beta-arrestin ubiquitination in agonist-promoted down-regulation of M1 vs M2 muscarinic acetylcholine receptors
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Motoki_2008_Am.J.Physiol.Heart.Circ.Physiol_295_H2128Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo
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Moustafa_2008_Jpn.J.Vet.Res_56_109Downregulation of male-specific cytochrome P450 by profenofos
Muccioli_2008_Chembiochem_9_2704CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay
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Mukherjee_2008_Biochemistry_47_6233PLP catabolism: identification of the 2-(Acetamidomethylene)succinate hydrolase gene in Mesorhizobium loti MAFF303099
Mulcahy_2008_Inorg.Chem_47_5030Solid-phase synthesis of tris-heteroleptic ruthenium(II) complexes and application to acetylcholinesterase inhibition
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Mumford_2008_J.Appl.Toxicol_28_694A novel approach to assessing percutaneous VX poisoning in the conscious guinea-pig
Munoz-Delgado_2008_Chem.Biol.Interact_175_340The expression of cholinesterases in human renal tumours varies according to their histological types
Munoz-Torrero_2008_Curr.Med.Chem_15_2433Acetylcholinesterase inhibitors as disease-modifying therapies for Alzheimer's disease
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Musilek_2008_Anal.Bioanal.Chem_391_367RP-HPLC determination of the lipophilicity of bispyridinium reactivators of acetylcholinesterase bearing a but-2-ene connecting linker
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Myhrer_2008_Pharmacol.Biochem.Behav_89_633Antiparkinson drugs used as prophylactics for nerve agents: studies of cognitive side effects in rats
Nachon_2008_Febs.J_275_2659Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel
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Nagy_2008_Genome.Res_18_1918Pathogen corruption and site-directed recombination at a plant disease resistance gene cluster
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Naito_2008_DNA.Res_15_215Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis
Naka_2008_Environ.Microbiol_10_265Reactivation of the vanchrobactin siderophore system of Vibrio anguillarum by removal of a chromosomal insertion sequence originated in plasmid pJM1 encoding the anguibactin siderophore system
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Nakajima_2008_J.Bacteriol_190_7819Dipeptidyl aminopeptidase IV from Stenotrophomonas maltophilia exhibits activity against a substrate containing a 4-hydroxyproline residue
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Nakou_2008_Expert.Opin.Pharmacother_9_3151The effects of ezetimibe and orlistat, alone or in combination, on high-density lipoprotein (HDL) subclasses and HDL-associated enzyme activities in overweight and obese patients with hyperlipidaemia
Nallapaneni_2008_Neurotoxicol_29_1037Pharmacological enhancement of endocannabinoid signaling reduces the cholinergic toxicity of diisopropylfluorophosphate
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Narbutaite_2008_Lett.Appl.Microbiol_47_555Influence of baking enzymes on antimicrobial activity of five bacteriocin-like inhibitory substances produced by lactic acid bacteria isolated from Lithuanian sourdoughs
Nathanson_2008_Pharmacol.Ther_119_33Synthesis, trafficking, and localization of muscarinic acetylcholine receptors
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Nawa_2008_Anticancer.Agents.Med.Chem_8_232Gene directed enzyme prodrug therapy for ovarian cancer: could GDEPT become a promising treatment against ovarian cancer?
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Neher_2008_Neuron_59_861Multiple roles of calcium ions in the regulation of neurotransmitter release
Nelson_2008_J.Med.Chem_51_3030Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists
Nelson_2008_J.Neurochem_107_602Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons
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Neoh_2008_Antimicrob.Agents.Chemother_52_45Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance
Neumiller_2008_Diabetes.Educ_34_183Looking to the future: focus on DPP-4 inhibitors for the treatment of type 2 diabetes and emerging therapies
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Niaura_2008_J.Phys.Chem.B_112_4094Probing of lipase activity at air/water interface by sum-frequency generation spectroscopy
Nicholls_2008_Neuron_58_104Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility
Nichols_2008_FEMS.Microbiol.Lett_284_52Identification and transcriptional profiling of Pseudomonas putida genes involved in furoic acid metabolism
Nicolakakis_2008_J.Neurosci_28_9287Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist
Niederhofer_2008_Drugs.Aging_25_715Acetylcholinesterase inhibitors may improve efficacy and reduce adverse effects of tricyclic antidepressants for depression
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Nilsson_2008_Genetics_179_375Caenorhabditis elegans num-1 negatively regulates endocytic recycling
Nimchua_2008_J.Ind.Microbiol.Biotechnol_35_843Screening of tropical fungi producing polyethylene terephthalate-hydrolyzing enzyme for fabric modification
Nirthanan_2008_J.Biol.Chem_283_22051Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector
Nishimune_2008_J.Cell.Biol_182_1201Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
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Nizri_2008_J.Neuroimmunol_203_12Suppression of neuroinflammation and immunomodulation by the acetylcholinesterase inhibitor rivastigmine
Nobrega_2008_Int.J.Cardiol_125_418Cholinergic stimulation with pyridostigmine prevents the impairment in ventricular function during mental stress in coronary artery disease patients
Nomura_2008_Bioorg.Med.Chem.Lett_18_5875Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels
Nomura_2008_Nat.Chem.Biol_4_373Activation of the endocannabinoid system by organophosphorus nerve agents
Nomura_2008_Toxicol.Appl.Pharmacol_228_42Dual roles of brain serine hydrolase KIAA1363 in ether lipid metabolism and organophosphate detoxification
Nong_2008_J.Toxicol.Environ.Health.A_71_1363Bayesian calibration of a physiologically based pharmacokinetic/pharmacodynamic model of carbaryl cholinesterase inhibition
Nordblad_2008_Biotechnol.Bioeng_99_1518Efficient enzymatic acrylation through transesterification at controlled water activity
Nordblad_2008_J.Biotechnol_133_127Effects of acid concentration and solvent choice on enzymatic acrylation by Candida antarctica lipase B
Noureddine_2008_J.Biol.Chem_283_20722Acetylcholinesterase associates differently with its anchoring proteins ColQ and PRiMA
Novakovic_2008_Acta.Crystallogr.C_64_o502Weak intermolecular interactions in 11-chloro-2,3,4,5-tetrahydro-1H-cyclohepta[b]quinoline
Nowack_2008_Curr.Biol_18_410Chromatophore genome sequence of Paulinella sheds light on acquisition of photosynthesis by eukaryotes
Nukoolkarn_2008_Bioorg.Med.Chem_16_6560Petrosamine, a potent anticholinesterase pyridoacridine alkaloid from a Thai marine sponge Petrosia n. sp
Nunes_2008_Biological.Bulletin_214_1Acetylcholine release and choline uptake by cuttlefish (Sepia officinalis) optic lobe synaptosomes
Nunes_2008_Neurosci.Lett_446_83Transthyretin knockout mouse nerves have increased lipoprotein lipase and sphingolipid content following crush
Nwosu_2008_Neurosci.Lett_441_282Impact of apoE deficiency during synaptic remodeling in the mouse olfactory bulb
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O'Donnell_2008_Fungal.Genet.Biol_45_1514Multilocus genotyping and molecular phylogenetics resolve a novel head blight pathogen within the Fusarium graminearum species complex from Ethiopia
O'Grady_2008_Appl.Environ.Microbiol_74_61Mutations in the lux operon of natural dark mutants in the genus Vibrio
Oboh_2008_J.Biochem.Mol.Toxicol_22_51Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase
Ogawa_2008_Biol.Pharm.Bull_31_1059Exosome-like vesicles with dipeptidyl peptidase IV in human saliva
Ogier_2008_Eur.J.Neurosci_28_924Pudendal motoneurons of the rat located in separated spinal nuclei possess nicotinic acetylcholine receptors having distinct pharmacological profiles
Ogura_2008_J.Bacteriol_190_6948Systematic identification and sequence analysis of the genomic islands of the enteropathogenic Escherichia coli strain B171-8 by the combined use of whole-genome PCR scanning and fosmid mapping
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Ohnishi_2008_J.Bacteriol_190_4050Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350
Ohnuma_2008_Front.Biosci_13_2299Role of CD26/dipeptidyl peptidase IV in human T cell activation and function
Ohsone_2008_Masui_57_838[Reversal of neuromuscular blockade and complications of remaining blocking effect]
Okada_2008_Gen.Comp.Endocrinol_155_623Differential display analysis of gene expression in female-to-male sex-reversing gonads of the frog Rana rugosa
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Okai_2008_Proteins_70_1646Crystal structure of the proline iminopeptidase-related protein TTHA1809 from Thermus thermophilus HB8
Okamura_2008_Br.J.Clin.Pharmacol_65_472In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease
Okazaki_2008_J.Biol.Chem_283_33357Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages
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Okuda_2008_J.Histochem.Cytochem_56_175Differential expression patterns of NDRG family proteins in the central nervous system
Okuno_2008_Toxicol.Appl.Pharmacol_227_8Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS
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Olkowicz_2008_J.Chem.Neuroanat_36_85Thalamic nuclei in the opossum Monodelphis domestica
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Ono_2008_Biol.Pharm.Bull_31_638Oseltamivir, an anti-influenza virus drug, produces hypothermia in mice
Onodera_2008_Chudoku.Kenkyu_21_161[Acute poisoning due to distigmine bromide]
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Oopik_2008_Eur.J.Neurol_15_246Clinical and laboratory-reconfirmed myasthenia gravis: a population-based study
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Orhan_2008_Z.Naturforsch.C_63_366Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity
Oropesa_2008_Environ.Toxicol_23_285Effect of long-term exposure to simazine on brain and muscle acetylcholinesterase activity of common carp (Cyprinus carpio)
Ortar_2008_J.Med.Chem_51_6970Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism
Osborne-Hereford_2008_J.Neuroimmunol_193_130Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation
Oshima_2008_DNA.Res_15_375Complete genome sequence and comparative analysis of the wild-type commensal Escherichia coli strain SE11 isolated from a healthy adult
Oshio_2008_J.Pediatr.Surg_43_222Imperforate anus, malrotation, and Hirschsprung's disease with double zonal aganglionosis: an extremely rare combination
Osipov_2008_J.Biol.Chem_283_14571Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification
Otyepka_2008_Proteins_70_707Second step of hydrolytic dehalogenation in haloalkane dehalogenase investigated by QM/MM methods
Otzen_2008_Colloids.Surf.B.Biointerfaces_64_223Differential adsorption of variants of the Thermomyces lanuginosus lipase on a hydrophobic surface suggests a role for local flexibility
Overshott_2008_Cochrane.Database.Syst.Rev__CD005317Cholinesterase inhibitors for delirium
Oyama_2008_Plant.Syst.Evol_273_257The shrunken genome of Arabidopsis thaliana.
Pacheco_2008_Pediatr.Dev.Pathol_11_274Variability of acetylcholinesterase hyperinnervation patterns in distal rectal suction biopsy specimens in Hirschsprung disease
Padwal_2008_Curr.Opin.Investig.Drugs_9_414Cetilistat, a new lipase inhibitor for the treatment of obesity
Page_2008_Cell.Mol.Life.Sci_65_1220Serine peptidases: classification, structure and function
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Palea_2008_J.Cataract.Refract.Surg_34_489Comparative effect of alfuzosin and tamsulosin on the contractile response of isolated rabbit prostatic and iris dilator smooth muscles: possible model for intraoperative floppy-iris syndrome
Pallasch_2008_Leukemia_22_585Targeting lipid metabolism by the lipoprotein lipase inhibitor orlistat results in apoptosis of B-cell chronic lymphocytic leukemia cells
Palmatier_2008_Neuropharmacol_55_1425The motivation to obtain nicotine-conditioned reinforcers depends on nicotine dose
Palmatier_2008_Neuropsychopharmacology_33_2139Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine
Palme_2008_Mol.Biol.Evol_25_2567Patterns of divergence among conifer ESTs and polymorphism in Pinus sylvestris identify putative selective sweeps
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Pan_2008_Diabet.Med_25_435Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial
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Paraje_2008_Can.J.Microbiol_54_647Candida albicans-secreted lipase induces injury and steatosis in immune and parenchymal cells
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Park_2008_BMB.Rep_41_254Purification and characterization of hepatic lipase from Todarodes pacificus
Park_2008_Bioresour.Technol_99_3130Lipase-catalyzed biodiesel production from waste activated bleaching earth as raw material in a pilot plant
Park_2008_Carcinogenesis_29_729Interactions of acetylcholinesterase with caveolin-1 and subsequently with cytochrome c are required for apoptosome formation
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Park_2008_J.Bacteriol_190_8086A novel thermostable arylesterase from the archaeon Sulfolobus solfataricus P1: purification, characterization, and expression
Park_2008_J.Mol.Biol_376_1426High-resolution structure of ybfF from Escherichia coli K12: a unique substrate-binding crevice generated by domain arrangement.
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Parmo-Folloni_2008_Chem.Biol.Interact_175_135Two new mutations of the human BCHE gene (IVS3-14T>C and L574fsX576)
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Pasarica_2008_Stem.Cells_26_969Adipogenic human adenovirus Ad-36 induces commitment, differentiation, and lipid accumulation in human adipose-derived stem cells
Pasquare_2008_Neurochem.Int_53_382Diacylglyceride lipase activity in rod outer segments depends on the illumination state of the retina
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Paterson_2008_Nicotine.Tob.Res_10_995Chronic bupropion differentially alters the reinforcing, reward-enhancing and conditioned motivational properties of nicotine in rats
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Pathiratne_2008_Arch.Environ.Contam.Toxicol_54_309Effects of biological and technical factors on brain and muscle cholinesterases in Nile tilapia, Oreochromis niloticus: implications for biomonitoring neurotoxic contaminations
Patinkin_2008_Eur.J.Pharmacol_595_1Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation
Pato_2008_Chem.Biol.Interact_175_64Role of lipid rafts in agrin-elicited acetylcholine receptor clustering
Patocka_2008_Curr.Drug.Metab_9_332Possible role of hydroxylated metabolites of tacrine in drug toxicity and therapy of Alzheimer's disease
Patrizi_2008_Proc.Natl.Acad.Sci.U.S.A_105_13151Synapse formation and clustering of neuroligin-2 in the absence of GABAA receptors
Paudyal_2008_JNMA.J.Nepal.Med.Assoc_47_251Organophosphorus poisoning
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Paula_2008_Pest.Manag.Sci_64_863Synthesis and insecticidal activity of new 3-benzylfuran-2-yl N,N,N,N-tetraethyldiamidophosphate derivatives
Paulick_2008_Biochemistry_47_6991The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins
Pauly_2008_PLoS.One_3_e2681Activity-dependent shedding of the NMDA receptor glycine binding site by matrix metalloproteinase 3: a PUTATIVE mechanism of postsynaptic plasticity
Paz_2008_Biophys.J_95_1928Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3
Pchelintsev_2008_Anal.Chim.Acta_612_190A novel procedure for rapid surface functionalisation and mediator loading of screen-printed carbon electrodes
Pearson_2008_J.Bacteriol_190_4027Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility
Pedersen_2008_J.Allergy.Clin.Immunol_122_322Airway responsiveness and inflammation in adolescent elite swimmers
Pedersen_2008_Regul.Pept_146_310Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects
Pedrosa_2008_Sensors.(Basel)_8_4600Determination of Parathion and Carbaryl Pesticides in Water and Food Samples Using a Self Assembled Monolayer /Acetylcholinesterase Electrochemical Biosensor
Pehrson_2008_Pharmacol.Biochem.Behav_89_424The effects of acute and repeated nicotine doses on spontaneous activity in male and female Sprague Dawley rats: analysis of brain area epibatidine binding and cotinine levels
Pei_2008_Curr.Opin.Drug.Discov.Devel_11_512From the bench to the bedside: dipeptidyl peptidase IV inhibitors, a new class of oral antihyperglycemic agents
Pejin_2008_J.Nat.Prod_71_1850Synthesis and biological activities of thio-avarol derivatives
Pelletier_2008_Endocrinology_149_6471Mice lacking the thyroid hormone receptor-alpha gene spend more energy in thermogenesis, burn more fat, and are less sensitive to high-fat diet-induced obesity
Pelton_2008_Int.J.Geriatr.Psychiatry_23_670Randomized double-blind placebo-controlled donepezil augmentation in antidepressant-treated elderly patients with depression and cognitive impairment: a pilot study
Peltzer_2008_Ecotoxicol.Environ.Saf_70_185Effects of agricultural pond eutrophication on survival and health status of Scinax nasicus tadpoles
Pena-Montes_2008_Appl.Microbiol.Biotechnol_78_603Purification and biochemical characterization of a broad substrate specificity thermostable alkaline protease from Aspergillus nidulans
Penco_2008_BMC.Bioinformatics_9_254New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background
Penfornis_2008_Diabetes.Metab_34 Suppl 2_S78Therapeutic approach of type 2 diabetes mellitus with GLP-1 based therapies
Peng_2008_Genomics_91_78Characterization of ST-4821 complex, a unique Neisseria meningitidis clone
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Pennetier_2008_Emerg.Infect.Dis_14_1707Mixture for controlling insecticide-resistant malaria vectors
Pereira_2008_Biochem.Pharmacol_75_1827Effects of estrogen on intracellular signaling pathways linked to activation of muscarinic acetylcholine receptors and on acetylcholinesterase activity in rat hippocampus
Pereira_2008_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_148_265Acute effects of diflubenzuron on the freshwater fish Prochilodus lineatus
Perera_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_247Polymorphism and partial characterization of digestive enzymes in the spiny lobster Panulirus argus
Perera_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_151_250Changes in digestive enzymes through developmental and molt stages in the spiny lobster, Panulirus argus
Perera_2008_Hum.Exp.Toxicol_27_513Comparison of two commonly practiced atropinization regimens in acute organophosphorus and carbamate poisoning, doubling doses vs. ad hoc: a prospective observational study
Perera_2008_Malar.J_7_168Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka
Perez-Burgos_2008_Neurosci_155_1079Muscarinic M(1) modulation of N and L types of calcium channels is mediated by protein kinase C in neostriatal neurons
Perez-Martinez_2008_Atheroscler.Suppl_9_49Influence of genetic factors in the modulation of postprandial lipemia
Perneczky_2008_MMW.Fortschr.Med_150_42[Diagnosis and therapy of Alzheimer's disease: what's important for the family doctor?]
Perrin_2008_Invert.Neurosci_8_147Thermal denaturation of wild type and mutant recombinant acetylcholinesterase from amphioxus: effects of the temperature of in vitro expression and of reversible inhibitors
Perry_2008_Insect.Biochem.Mol.Biol_38_520Mutations in Dalpha1 or Dbeta2 nicotinic acetylcholine receptor subunits can confer resistance to neonicotinoids in Drosophila melanogaster
Petek_2008_Acta.Biochim.Pol_55_97Tenocyclidine treatment in soman-poisoned rats--intriguing results on genotoxicity versus protection
Peter_2008_Anaesth.Intensive.Care_36_339Adjuncts and alternatives to oxime therapy in organophosphate poisoning--is there evidence of benefit in human poisoning? A review
Peter_2008_Lancet_371_622In-laws, insecticide--and a mimic of brain death
Peter_2008_Neurotoxicol_29_335Delayed-onset encephalopathy and coma in acute organophosphate poisoning in humans
Petraglio_2008_Proteins_70_779The role of Li+, Na+, and K+ in the ligand binding inside the human acetylcholinesterase gorge
Petroianu_2008_Mini.Rev.Med.Chem_8_1328Pyridinium oxime reactivators of cholinesterase inhibited by diisopropyl-fluorophosphate (DFP): predictive value of in-vitro testing for in-vivo efficacy
Petroianu_2008_Pharmazie_63_325The history of cholinesterase inhibitors: who was Moschnin(e)?
Pfeiffer_2008_Genomics_91_335Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1
Pham_2008_Am.J.Health.Syst.Pharm_65_521Sitagliptin: a novel agent for the management of type 2 diabetes mellitus
Phoopichayanun_2008_Nat.Prod.Res_22_1297Complete NMR assignment and absolute configuration of feronielloside, a new acetylcholinesterase inhibitor from Feroniella lucida
Phowichit_2008_Commun.Agric.Appl.Biol.Sci_73_611Insecticidal activity of Jatropha gossypifolia L. (Euphorbiaceae) and Cleome viscosa L. (Capparidacae) on Spodoptera litura (Lepidoptera: Noctuidae). Toxicity and carboxylesterase and glutathione-S-transferase activities studies
Pi-Sunyer_2008_Postgrad.Med_120_5The effects of pharmacologic agents for type 2 diabetes mellitus on body weight
Piazzi_2008_Bioorg.Med.Chem.Lett_18_423Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds
Pibiri_2008_Proc.Natl.Acad.Sci.U.S.A_105_14169The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice
Picardeau_2008_PLoS.ONE_3_E1607Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis
Piccione_2008_J.Vet.Diagn.Invest_20_795Daily rhythm of serum lipase and alpha-amylase activity in fed and fasted dogs
Picciotto_2008_Front.Biosci_13_492Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease
Picciotto_2008_Prog.Neurobiol_84_329It is not either/or: activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood
Picco_2008_J.Environ.Sci.Health.B_43_405Use of cholinesterase activity in monitoring chlorpyrifos exposure of steer cattle after topical administration
Picco_2008_Vet.Res.Commun_32_401Pharmacokinetics and pharmacodynamics of chlorpyrifos in male and female cattle after topical administration
Picollo_2008_Fitoterapia_79_271Anticholinesterase and pediculicidal activities of monoterpenoids
Pidot_2008_BMC.Genomics_9_462Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones
Pigot_2008_J.ECT_24_57Pharmacological attenuation of electroconvulsive therapy--induced cognitive deficits: theoretical background and clinical findings
Pinent_2008_Genomics_92_26Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice
Pinheiro_2008_Appl.Biochem.Biotechnol_146_203Response surface methodology as an approach to determine optimal activities of lipase entrapped in sol-gel matrix using different vegetable oils
Pinthong_2008_Mol.Pharmacol_73_801Activity and subcellular trafficking of the sodium-coupled choline transporter CHT is regulated acutely by peroxynitrite
Pio_2008_J.Ind.Microbiol.Biotechnol_35_59Cutinase production by Fusarium oxysporum in liquid medium using central composite design
Pitt_2008_J.Neurosci_28_11454High intracellular chloride slows the decay of glycinergic currents
Podolska_2008_Pestic.Biochem.Physiol_91_104The impact of carbofuran on acetylcholinesterase activity in Anisakis simplex larvae from Baltic herring
Podoly_2008_Neurodegener.Dis_5_232Human recombinant butyrylcholinesterase purified from the milk of transgenic goats interacts with beta-amyloid fibrils and suppresses their formation in vitro
Poewe_2008_Int.J.Clin.Pract_62_1581Diagnosis and management of Parkinson's disease dementia
Poewe_2008_Pract.Neurol_8_238When a Parkinson's disease patient starts to hallucinate
Pohanka_2008_J.Enzyme.Inhib.Med.Chem_23_781Photometric microplate assay for estimation of the efficacy of paraoxon-inhibited acetylcholinesterase reactivation
Pohanka_2008_Neuro.Endocrinol.Lett_29_755New performance of biosensor technology for Alzheimer's disease drugs: in vitro comparison of tacrine and 7-methoxytacrine
Pohanka_2008_Protein.Pept.Lett_15_795Cholinesterase biosensor construction - a review
Pohanka_2008_Sensors.(Basel)_8_5229Diagnosis of Intoxication by the Organophosphate VX: Comparison Between an Electrochemical Sensor and Ellman s Photometric Method
Pohanka_2008_Sensors.(Basel)_8_5303Amperometric Biosensors for Real Time Assays of Organophosphates
Poisik_2008_J.Physiol_586_1365Functional alpha7-containing nicotinic acetylcholine receptors localize to cell bodies and proximal dendrites in the rat substantia nigra pars reticulata
Polizelli_2008_Appl.Biochem.Biotechnol_150_233A new lipase isolated from oleaginous seeds from Pachira aquatica (Bombacaceae)
Ponce_2008_J.Cell.Biochem_104_1342Coexpression of osteogenic and adipogenic differentiation markers in selected subpopulations of primary human mesenchymal progenitor cells
Ponnappa_2008_Peptides_29_1893INN-toxin, a highly lethal peptide from the venom of Indian cobra (Naja naja) venom-Isolation, characterization and pharmacological actions
Pons_2008_J.Neurosci_28_12318Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration
Poole_2008_Brain.Inj_22_519Cholinomimetic agents and neurocognitive impairment following head injury: a systematic review
Pope_2008_FEMS.Microbiol.Ecol_64_9Metagenomic analysis of a freshwater toxic cyanobacteria bloom
Porsteinsson_2008_Curr.Alzheimer.Res_5_83Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial
Pospisil_2008_Photochem.Photobiol.Sci_7_625Photochemical synthesis of substituted indan-1-ones related to donepezil
Potter_2008_Pharmacol.Biochem.Behav_88_407Acute nicotine improves cognitive deficits in young adults with attention-deficit/hyperactivity disorder
Potumarthi_2008_Appl.Biochem.Biotechnol_151_700Effect of aeration and agitation regimes on lipase production by newly isolated Rhodotorula mucilaginosa-MTCC 8737 in stirred tank reactor using molasses as sole production medium
Poupardin_2008_Insect.Biochem.Mol.Biol_38_540Cross-induction of detoxification genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti: impact on larval tolerance to chemical insecticides
Prabhu_2008_Indian.J.Clin.Biochem_23_98A preliminary study of protein thiols and serum cholinesterase in assisted reproduction
Pratley_2008_Medscape.J.Med_10_171Overview of glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors for type 2 diabetes
Pratley_2008_Rev.Diabet.Stud_5_73Targeting Incretins in Type 2 Diabetes: Role of GLP-1 Receptor Agonists and DPP-4 Inhibitors
Printes_2008_Ecotoxicol.Environ.Saf_71_519Clonal variation in acetylcholinesterase biomarkers and life history traits following OP exposure in Daphnia magna
Prokai_2008_Chromatographia_68_s101Measurement of Acetylcholine in Rat Brain Microdialysates by LC - Isotope Dilution Tandem MS
Proskocil_2008_Environ.Health.Perspect_116_381Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity
Prus_2008_Pharmacol.Biochem.Behav_91_150Acute nicotine reduces and repeated nicotine increases spontaneous activity in male and female Lewis rats
Pu_2008_Int.J.Oral.Maxillofac.Surg_37_567Trapezius muscle innervation from the spinal accessory nerve and branches of the cervical plexus
Puech-Guenot_2008_J.Biomol.Screen_13_72Small-scale production of Burkholderia cepacia ATCC21808 lipase adapted to high-throughput screening
Punga_2008_Muscle.Nerve_37_300Electrophysiological signs and the prevalence of adverse effects of acetylcholinesterase inhibitors in patients with myasthenia gravis
Puntel_2008_Arch.Toxicol_82_755Antioxidant properties of oxime 3-(phenylhydrazono) butan-2-one
Pushparajah_2008_Mutat.Res_640_153Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: studies using precision-cut tissue slices
Puthanveettil_2008_Cell_135_960A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex
Putnam_2008_Nature_453_1064The amphioxus genome and the evolution of the chordate karyotype
Putz_2008_J.Neurosci.Res_86_972Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes
Qaseem_2008_Ann.Intern.Med_148_370Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians
Qi_2008_Zhongguo.Xiu.Fu.Chong.Jian.Wai.Ke.Za.Zhi_22_1031[Preliminary research of 3D reconstruction of short-segment common peroneal nerve functional fascicles]
Qian_2008_BMC.Neurosci_9_70The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
Qin_2008_Invest.Ophthalmol.Vis.Sci_49_1274Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells
Qiu_2008_Microbiology_154_2119ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa
Qiu_2008_Postgrad.Med.J_84_498Association study between adolescent idiopathic scoliosis and the DPP9 gene which is located in the candidate region identified by linkage analysis
Qu_2008_Dev.Biol_317_486Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish
Quintaneiro_2008_Chemosphere_71_1803Transport and acclimation conditions for the use of an estuarine fish (Pomatoschistus microps) in ecotoxicity bioassays: effects on enzymatic biomarkers
Quitschau_2008_Eur.J.Org.Chem_5117The New Metabolite (S)-Cinnamoylphosphoramide from Streptomyces sp. and Its Total Synthesis
Qureshi_2008_Pest.Manag.Sci_64_1159Rate, placement and timing of aldicarb applications to control Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), in oranges
Rachokarn_2008_Commun.Agric.Appl.Biol.Sci_73_451Impact of botanical extracts derived from leaf extracts Melia azedarach L. (Meliaceae) and Amaranthus viridis L. (Amaranthaceae) on populations of Spodoptera exigua (Hubner) (Lepidoptera: Noctuidae) and detoxification enzyme activities
Radchenko_2008_Dokl.Biochem.Biophys_418_47Modeling of the relationships between the structure of O-phosphorylated oximes and their anticholinesterase activity and selectivity using molecular field topology analysis (MFTA)
Radic_2008_Chem.Biol.Interact_175_161Probing gorge dimensions of cholinesterases by freeze-frame click chemistry
Rahman_2008_Br.J.Pharmacol_153_792Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo
Rahman_2008_CNS.Neurol.Disord.Drug.Targets_7_422Neuronal nicotinic receptors as brain targets for pharmacotherapy of drug addiction
Rahman_2008_Eur.J.Pharmacol_601_103The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens
Rahnasto_2008_Pharmacogenomics.J_8_328Identification of inhibitors of the nicotine metabolising CYP2A6 enzyme--an in silico approach
Raina_2008_Ann.Intern.Med_148_379Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline
Raina_2008_J.Agric.Food.Chem_56_6594New metabolites in the degradation of alpha- and gamma-hexachlorocyclohexane (HCH): pentachlorocyclohexenes are hydroxylated to cyclohexenols and cyclohexenediols by the haloalkane dehalogenase LinB from Sphingobium indicum B90A
Rajakumara_2008_Biochim.Biophys.Acta_1784_302Structural basis for the remarkable stability of Bacillus subtilis lipase (Lip A) at low pH
Rajan_2008_Bioprocess.Biosyst.Eng_31_87Studies on crystallization and cross-linking of lipase for biocatalysis
Rajini_2008_J.Toxicol.Environ.Health.A_71_1043A comparative study on the relationship between various toxicological endpoints in Caenorhabditis elegans exposed to organophosphorus insecticides
Raldua_2008_Chemosphere_73_56First evidence of polybrominated diphenyl ether (flame retardants) effects in feral barbel from the Ebro River basin (NE, Spain)
Ralph_2008_BMC.Genomics_9_484A conifer genomics resource of 200,000 spruce (Picea spp.) ESTs and 6,464 high-quality, sequence-finished full-length cDNAs for Sitka spruce (Picea sitchensis)
Ralph_2008_BMC.Genomics_9_57Analysis of 4,664 high-quality sequence-finished poplar full-length cDNA clones and their utility for the discovery of genes responding to insect feeding
Raman_2008_BMC.Syst.Biol_2_109targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis
Ramanujam_2008_Aquaculture_283_77Effect of alcohol extract of a natural piscicide -- Fruits of Zanthoxylum armatum DC. on Mg2+- and Na+, K+-ATPase activity in various tissues of a freshwater air-breathing fish, Heteropneustes fossilis
Ramirez_2008_Appl.Biochem.Biotechnol_151_711A new microplate screening method for the simultaneous activity quantification of feruloyl esterases, tannases, and chlorogenate esterases
Randolt_2008_Arch.Insect.Biochem.Physiol_69_155Immune-related proteins induced in the hemolymph after aseptic and septic injury differ in honey bee worker larvae and adults
Rao_2008_Bioinform.Biol.Insights_2_1Proteomic analysis in diabetic cardiomyopathy using bioinformatics approach
Rao_2008_Med.Hypotheses_70_148Bioinformatics analysis of diabetic retinopathy using functional protein sequences
Rasko_2008_J.Bacteriol_190_6881The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates
Raveh_2008_Toxicol.Appl.Pharmacol_227_155Efficacy of antidotal treatment against sarin poisoning: the superiority of benactyzine and caramiphen
Rawlings_2008_Biochimie_90_243The MEROPS batch BLAST: a tool to detect peptidases and their non-peptidase homologues in a genome
Rawlings_2008_Nucleic.Acids.Res_36_D320MEROPS: the peptidase database
Raymond_2008_Extremophiles_12_713A bacterial ice-binding protein from the Vostok ice core
Razay_2008_Expert.Rev.Neurother_8_9Galantamine in Alzheimer's disease
Reale_2008_J.Alzheimers.Dis_14_147Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease
Rebolledo_2008_Mol.Neurobiol_38_178Inclusion body myositis: a view from the Caenorhabditis elegans muscle
Reddy_2008_Curr.Opin.Lipidol_19_405Is it just paraoxonase 1 or are other members of the paraoxonase gene family implicated in atherosclerosis?
Redig_2008_Vet.Clin.North.Am.Exot.Anim.Pract_11_261Raptor toxicology
Redka_2008_Mol.Pharmacol_74_834Binding of orthosteric ligands to the allosteric site of the M(2) muscarinic cholinergic receptor
Reese_2008_Aging.Cell_7_824Selective induction of calcineurin activity and signaling by oligomeric amyloid beta
Reetz_2008_Chem.Commun.(Camb)__5502A genetic selection system for evolving enantioselectivity of enzymes
Reeves_2008_Appl.Environ.Microbiol_74_5121Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia
Reeves_2008_Protein.Eng.Des.Sel_21_405Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities
Rehberg_2008_Cell.Calcium_44_386A new non-disruptive strategy to target calcium indicator dyes to the endoplasmic reticulum
Rehiman_2008_JNMA.J.Nepal.Med.Assoc_47_47Correlation of serum cholinesterase level, clinical score at presentation and severity of organophosphorous poisoning
Reid_2008_J.Biol.Chem_283_13087Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis
Reid_2008_J.Neural.Transm.(Vienna)_115_1437Effects of cholinesterase inhibitors on rat nicotinic receptor levels in vivo and in vitro
Reiner_2008_Life.Sci_82_718The internalization of the M2 and M4 muscarinic acetylcholine receptors involves distinct subsets of small G-proteins
Reinhold_2008_Front.Biosci_13_2356DP IV/CD26, APN/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis
Reis_2008_Langmuir_24_6812Lipases at interfaces: unique interfacial properties as globular proteins
Reis_2008_Langmuir_24_7400Competition between lipases and monoglycerides at interfaces
Reissner_2008_Proc.Natl.Acad.Sci.U.S.A_105_15124Mutational analysis of the neurexin/neuroligin complex reveals essential and regulatory components
Reiter_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_873_86Chromatographic resolution, characterisation and quantification of VX enantiomers in hemolysed swine blood samples
Reith_2008_BMC.Genomics_9_427The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen
Remelli_2008_J.Neurochem_104_1020The C-terminus of the metabotropic glutamate receptor 1b regulates dimerization of the receptor
Remmler_2008_Expert.Opin.Pharmacother_9_363Pharmacogenomics in acute coronary syndrome
Ren_2008_J.Agric.Food.Chem_56_2388pH memory of immobilized lipase for (+/-)-menthol resolution in ionic liquid
Ren_2008_Pestic.Biochem.Physiol_90_196Comparison of acetylcholinesterase from three field populations of Liposcelis paeta Pearman (Psocoptera: Liposcelididae): Implications of insecticide resistance
Rengarajan_2008_Proc.Natl.Acad.Sci.U.S.A_105_264Mycobacterium tuberculosis Rv2224c modulates innate immune responses
Rensing_2008_Science_319_64The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants
Renwick_2008_Food.Chem.Toxicol_46_1206Re: The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study
Reshma_2008_Bioresour.Technol_99_5011Lipase catalyzed interesterification of palm stearin and rice bran oil blends for preparation of zero trans shortening with bioactive phytochemicals
Reysenbach_2008_Geobiology_6_331Electron microscopy encounters with unusual thermophiles helps direct genomic analysis of Aciduliprofundum boonei
Rezg_2008_C.R.Biol_331_655Biochemical evaluation of hepatic damage in subchronic exposure to malathion in rats: effect on superoxide dismutase and catalase activities using native PAGE
Rezg_2008_Toxicology_250_27Caffeic acid attenuates malathion induced metabolic disruption in rat liver, involvement of acetylcholinesterase activity
Ribelles_2008_Curr.Drug.Metab_9_336A carboxylesterase 2 gene polymorphism as predictor of capecitabine on response and time to progression
Ricart-Jane_2008_Cell.Physiol.Biochem_22_525Nitric oxide and the release of lipoprotein lipase from white adipose tissue
Ricci_2008_Pulm.Pharmacol.Ther_21_79Changes in muscarinic cholinergic receptor expression in human peripheral blood lymphocytes in allergic rhinitis patients
Richard_2008_Neurology_71_1967The CHRNE 1293insG founder mutation is a frequent cause of congenital myasthenia in North Africa
Richards_2008_Nature_452_949The genome of the model beetle and pest Tribolium castaneum
Richter_2008_Circ.Cardiovasc.Genet_1_147Determination of paraoxonase 1 status without the use of toxic organophosphate substrates
Richter_2008_Cochrane.Database.Syst.Rev__CD006739Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus
Richter_2008_Vasc.Health.Risk.Manag_4_753Emerging role of dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes
Ridl_2008_Malar.J_7_194A pre-intervention study of malaria vector abundance in Rio Muni, Equatorial Guinea: their role in malaria transmission and the incidence of insecticide resistance alleles
Rimmerman_2008_Br.J.Pharmacol_153_380Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line
Rispoli_2008_Biotechnol.Prog_24_648Optimization of the media ingredients for cutinase production from Colleotrichum lindemuthianum using mixture design experiments
Rivellese_2008_Clin.Nutr_27_133Effects of monounsaturated vs. saturated fat on postprandial lipemia and adipose tissue lipases in type 2 diabetes
Rivera-Becerril_2008_J.Med.Chem_51_5271Synthesis and biological evaluation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitors
Rizzi_2008_Bioorg.Med.Chem.Lett_18_4651Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes
Rizzo_2008_J.Med.Chem_51_2883Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity
Robaszkiewicz_2008_Mech.Ageing.Dev_129_572N-chloroamino acids cause oxidative protein modifications in the erythrocyte membrane
Robert_2008_Genetics_180_673Gene conversion and end-joining-repair double-strand breaks in the Caenorhabditis elegans germline
Rocha-Rego_2008_Brain.Res.Bull_76_26Architectonic subdivisions of the amygdalar complex of a primitive marsupial (Didelphis aurita)
Rocha_2008_Mol.Plant.Pathol_9_293Ctf1, a transcriptional activator of cutinase and lipase genes in Fusarium oxysporum is dispensable for virulence
Rock_2008_J.Agric.Food.Chem_56_8704Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-density lipoprotein and stimulates its catalytic activities
Rocksen_2008_Toxicology_250_32An animal model to study health effects during continuous low-dose exposure to the nerve agent VX
Rockwood_2008_Int.J.Geriatr.Psychiatry_23_207Patterns of decline and evidence of subgroups in patients with Alzheimer's disease taking galantamine for up to 48 months
Roder_2008_PLoS.One_3_e3871Role of Myosin Va in the plasticity of the vertebrate neuromuscular junction in vivo
Rodrigues_2008_Neurobiol.Aging_29_1597Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats
Rodriguez-Fuentes_2008_Ecotoxicol.Environ.Saf_69_466Characterization of muscle cholinesterases from two demersal flatfish collected near a municipal wastewater outfall in Southern California
Rodriguez-Perez_2008_Nucleic.Acids.Symp.Ser.(Oxf)__101Preparation of nucleoside-carbohydrate phosphodiester prodrug analogues by chemoenzymatic procedure
Rodriguez_2008_Anal.Biochem_375_196Novel chromatographic resolution of chiral diacylglycerols and analysis of the stereoselective hydrolysis of triacylglycerols by lipases
Rodriguez_2008_Int.J.Food.Microbiol_121_92Characterization of tannase activity in cell-free extracts of Lactobacillus plantarum CECT 748T
Roegge_2008_Brain.Res.Bull_75_166Developmental diazinon neurotoxicity in rats: later effects on emotional response
Rogers_2008_Hippocampus_18_750Mouse chromosome 11 harbors genetic determinants of hippocampal strain-specific nicotinic receptor expression
Rogozhin_2008_J.Physiol_586_3163Recovery of mouse neuromuscular junctions from single and repeated injections of botulinum neurotoxin A
Roh_2008_Ecotoxicol.Environ.Saf_71_483Ecotoxicological evaluation of chlorpyrifos exposure on the nematode Caenorhabditis elegans
Roh_2008_J.Appl.Microbiol_105_116Isolation of a low-temperature adapted lipolytic enzyme from uncultivated micro-organism
Roland_2008_Brain.Res_1234_116Increasing hippocampal acetylcholine levels enhance behavioral performance in an animal model of diencephalic amnesia
Roncarati_2008_Assay.Drug.Dev.Technol_6_181Functional properties of alpha7 nicotinic acetylcholine receptors co-expressed with RIC-3 in a stable recombinant CHO-K1 cell line
Ronchetti_2008_J.Hepatol_49_474Severe steatohepatitis in a patient with a rare neutral lipid storage disorder due to ABHD5 mutation
Rosas-Ballina_2008_Proc.Natl.Acad.Sci.U.S.A_105_11008Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia
Rosell_2008_J.Pestic.Sci_33_103Biorational insecticides in pest management
Rosenberry_2008_Biochemistry_47_13056Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter
Rosenberry_2008_Chem.Biol.Interact_175_235Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis
Rosenblat_2008_J.Nutr.Biochem_19_514Antiatherogenicity of extra virgin olive oil and its enrichment with green tea polyphenols in the atherosclerotic apolipoprotein-E-deficient mice: enhanced macrophage cholesterol efflux
Rosenblatt_2008_Int.J.Geriatr.Psychiatry_23_178Acetylcholinesterase inhibitors in assisted living: patterns of use and association with retention
Rosethorne_2008_Biochem.Pharmacol_75_942Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells
Rosini_2008_J.Med.Chem_51_4381Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush
Ross_2008_Dev.Neurobiol_68_409Capabilities of neurexins in the chick ciliary ganglion
Rotundo_2008_Chem.Biol.Interact_175_26Assembly and regulation of acetylcholinesterase at the vertebrate neuromuscular junction
Rouhani_2008_Lipids_43_793HDL composition regulates displacement of cell surface-bound hepatic lipase
Rowland_2008_Chem.Biol.Interact_175_73Inactivation of an invertebrate acetylcholinesterase by sulfhydryl reagents: a reconsideration of the implications for insecticide design
Roxas_2008_Altern.Med.Rev_13_307The role of enzyme supplementation in digestive disorders
Roy_2008_J.Mol.Graph.Model_27_197An investigation of structurally diverse carbamates for acetylcholinesterase (AChE) inhibition using 3D-QSAR analysis
Rozenberg_2008_Free.Radic.Biol.Med_44_1951Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties
Rozengart_2008_Dokl.Biochem.Biophys_418_1New substrates and reversible inhibitors of cholinesterases based on esters and thioesters of noncholine cyclic ammonium alcohols
Rozengart_2008_Dokl.Biochem.Biophys_419_82A comparative study of antichymotryptic and anticholinesterase activity of organophosphorus quasi-substrate inhibitors
Rozengart_2008_Dokl.Biochem.Biophys_421_218Specificity of cholinesterase hydrolysis of piperidylcholine and its derivatives
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Rozsa_2008_Eur.J.Neurosci_27_364Dendritic nicotinic receptors modulate backpropagating action potentials and long-term plasticity of interneurons
Rozzini_2008_Aging.Clin.Exp.Res_20_509Serum albumin level interferes with the effect of Donepezil in Alzheimer's disease
Rubio_2008_Arq.Bras.Endocrinol.Metabol_52_1337A molecular analysis and long-term follow-up of two siblings with severe congenital hypothyroidism carrying the IVS30+1G>T intronic thyroglobulin mutation
Rubio_2008_Curr.Genet_54_301Cloning and characterization of the Thcut1 gene encoding a cutinase of Trichoderma harzianum T34
Ruby_2008_Proc.Natl.Acad.Sci.U.S.A_105_14561Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins
Ruchi_2008_Bioresour.Technol_99_4796Lipase from solvent tolerant Pseudomonas aeruginosa strain: production optimization by response surface methodology and application
Rueda_2008_Neurosci.Lett_433_22Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome
Ruff_2008_J.Neuroimmunol_201-202_13How myasthenia gravis alters the safety factor for neuromuscular transmission
Russon_2008_Anaesthesia_63_210Drug incompatibility reaction with use of fluorescein during anaesthesia
Rusted_2008_Psychopharmacology.(Berl)_196_83Nicotine effects on retrieval-induced forgetting are not attributable to changes in arousal
Ryu_2008_Front.Biosci_13_777Development of Alzheimer's disease imaging agents for clinical studies
Ryuda_2008_Zoolog.Sci_25_746Analysis of hunger-driven gene expression in the Drosophila melanogaster larval central nervous system
Saarela_2008_BMC.Genomics_9_281The patatin-like lipase family in Gallus gallus
Saccone_2008_Bioinformatics_24_1805Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence
Sachana_2008_Toxicol.In.Vitro_22_1387Inhibition of extension outgrowth in differentiating rat C6 glioma cells by chlorpyrifos and chlorpyrifos oxon: effects on microtubule proteins
Saerens_2008_Biotechnol.Lett_30_311Release of short chain fatty acids from cream lipids by commercial lipases and esterases
Sagiroglu_2008_Artif.Cells.Blood.Substit.Immobil.Biotechnol_36_138Conversion of sunflower oil to biodiesel by alcoholysis using immobilized lipase
Sagoo_2008_Am.J.Epidemiol_168_1233Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis
Saha_2008_FEBS.Lett_582_3823RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis
Saied_2008_J.Asian.Nat.Prod.Res_10_515Two new coumarins from Murraya paniculata
Saiki_2008_Metabolism_57_1093Suppression of lipoprotein lipase expression in 3T3-L1 cells by inhibition of adipogenic differentiation through activation of the renin-angiotensin system
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Saisubramanian_2008_Appl.Biochem.Biotechnol_150_139Two step purification of Acinetobacter sp. lipase and its evaluation as a detergent additive at low temperatures
Sakai_2008_J.Biosci.Bioeng_105_687Transesterification by lipase entrapped in electrospun poly(vinyl alcohol) fibers and its application to a flow-through reactor
Sakai_2008_J.Biosci.Bioeng_106_466Construction of a citrinin gene cluster expression system in heterologous Aspergillus oryzae
Sakakibara_2008_Carbohydr.Res_343_2740A facile synthesis of 4,6-O-benzylidene-D-glycals via 1,5-anhydro-4,6-O-benzylidene-D-hex-1-en-3-ulose
Sakayama_2008_Anticancer.Res_28_2081The synthesis and activity of lipoprotein lipase in the subcutaneous adipose tissue of patients with musculoskeletal sarcomas
Sakayama_2008_Cancer.Chemother.Pharmacol_61_471Effect of cortisol on cell proliferation and the expression of lipoprotein lipase and vascular endothelial growth factor in a human osteosarcoma cell line
Sala_2008_Acta.Physiol.(Oxf)_192_203Nicotinic acetylcholine receptors of adrenal chromaffin cells
Salas_2008_Mol.Pharmacol_74_1641Nicotine relieves anxiogenic-like behavior in mice that overexpress the read-through variant of acetylcholinesterase but not in wild-type mice
Salazar_2008_Nat.Neurosci_11_255A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic
Salloway_2008_Int.Psychogeriatr_20_40Key lessons learned from short-term treatment trials of cholinesterase inhibitors for amnestic MCI
Salmon_2008_Rev.Med.Liege_63_570[A transdermal patch of rivastigmine (Exelon)]
Salzberg_2008_BMC.Genomics_9_204Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99A
Samanta_2008_J.Biol.Chem_283_31617Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis
Samarawickrema_2008_Clin.Toxicol.(Phila)_46_489Fetal effects of environmental exposure of pregnant women to organophosphorus compounds in a rural farming community in Sri Lanka
Sanchez-Otero_2008_J.Ind.Microbiol.Biotechnol_35_1687Immobilization in the presence of Triton X-100: modifications in activity and thermostability of Geobacillus thermoleovorans CCR11 lipase
Sanchis_2008_Appl.Microbiol.Biotechnol_81_387Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates
Sandra_2008_J.Agric.Food.Chem_56_7488Effect of interfacial protein cross-linking on the in vitro digestibility of emulsified corn oil by pancreatic lipase
Sanghvi_2008_Biochim.Biophys.Acta_1778_2690Identifying the binding site(s) for antidepressants on the Torpedo nicotinic acetylcholine receptor: [3H]2-azidoimipramine photolabeling and molecular dynamics studies
Sangnoi_2008_Mar.Drugs_6_578Acetylcholinesterase-inhibiting activity of pyrrole derivatives from a novel marine gliding bacterium, Rapidithrix thailandica
Sanki_2008_Bioorg.Med.Chem_16_5672Synthesis of methyl 5-S-alkyl-5-thio-D-arabinofuranosides and evaluation of their antimycobacterial activity
Sann_2008_J.Neurosci_28_2366Neurite outgrowth and in vivo sensory innervation mediated by a Ca(V)2.2-laminin beta 2 stop signal
Sano_2008_CNS.Drugs_22_887Preventing Alzheimer's disease : separating fact from fiction
Sanogo_2008_J.Med.Entomol_45_203Identification of male specimens of the Culex pipiens complex (Diptera: Culicidae) in the hybrid zone using morphology and molecular techniques
Santos_2008_Colloids.Surf.B.Biointerfaces_61_229Covalent attachment of Candida rugosa lipase on chemically modified hybrid matrix of polysiloxane-polyvinyl alcohol with different activating compounds
Santos_2008_J.Phys.Chem.B_112_3581Orientation of cutinase adsorbed onto PMMA nanoparticles probed by tryptophan fluorescence
Santos_2008_Pediatr.Surg.Int_24_715Study of acetylcholinesterase activity in rectal suction biopsy for diagnosis of intestinal dysganglionoses: 17-year experience of a single center
Sardana_2008_Clin.Chem_54_1951Emerging biomarkers for the diagnosis and prognosis of prostate cancer
Sarica_2008_Obesity.(Silver.Spring)_16_1579Evaluation of urinary oxalate levels in patients receiving gastrointestinal lipase inhibitor
Satin_2008_Stem.Cells_26_1961Calcium handling in human embryonic stem cell-derived cardiomyocytes
Sattigeri_2008_Bioorg.Med.Chem.Lett_18_4087Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors
Sattley_2008_J.Bacteriol_190_4687The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus
Saulsbury_2008_Toxicology_244_98Characterization of chlorpyrifos-induced apoptosis in placental cells
Savage_2008_J.Med.Entomol_45_276Host-seeking heights, host-seeking activity patterns, and West Nile virus infection rates for members of the Culex pipiens complex at different habitat types within the hybrid zone, Shelby County, TN, 2002 (Diptera: Culicidae)
Savontaus_2008_Eur.J.Pharmacol_578_359Reduced blood glucose levels, increased insulin levels and improved glucose tolerance in alpha2A-adrenoceptor knockout mice
Saw_2008_Genome.Biol_9_R161Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1
Saxena_2008_Chem.Biol.Interact_175_267Efficacy of human serum butyrylcholinesterase against sarin vapor
Saxena_2008_Eur.J.Pharmacol_581_283Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice
Saxena_2008_Protein.Expr.Purif_61_191Developing procedures for the large-scale purification of human serum butyrylcholinesterase
Schade_2008_J.Histochem.Cytochem_56_147Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats
Schaeffer_2008_Psychopharmacology.(Berl)_198_1Cholinergic and glutamatergic alterations beginning at the early stages of Alzheimer disease: participation of the phospholipase A2 enzyme
Schafellner_2008_J.Insect.Physiol_54_916Juvenile hormone esterase activity in the pupating and diapausing larvae of Sesamia nonagrioides
Schara_2008_Neurotherapeutics_5_542Therapeutic strategies in congenital myasthenic syndromes
Scherma_2008_CNS.Neurol.Disord.Drug.Targets_7_468The endocannabinoid system: a new molecular target for the treatment of tobacco addiction
Scheuhammer_2008_Ecotoxicology_17_93Relationships among mercury, selenium, and neurochemical parameters in common loons (Gavia immer) and bald eagles (Haliaeetus leucocephalus)
Schilke_2008_Biotechnol.Bioeng_101_9Activation of immobilized lipase in non-aqueous systems by hydrophobic poly-DL-tryptophan tethers
Schmidt_2008_Clin.Nucl.Med_33_398Value of combining activated brain FDG-PET and cardiac MIBG for the differential diagnosis of dementia: differentiation of dementia with Lewy bodies and Alzheimer disease when the diagnoses based on clinical and neuroimaging criteria are difficult
Schmidt_2008_J.Biol.Chem_283_21827Atomic resolution crystal structures and quantum chemistry meet to reveal subtleties of hydroxynitrile lyase catalysis
Schneider_2008_Fungal.Genet.Biol_45_1487Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides
Schneider_2008_Fungal.Genet.Biol_45_302The Aspergillus nidulans enzyme TdiB catalyzes prenyltransfer to the precursor of bioactive asterriquinones
Schoen_2008_Proc.Natl.Acad.Sci.U.S.A_105_3473Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis
Schoffelen_2008_Bioconjug.Chem_19_1127Site-specific modification of Candida antarctica lipase B via residue-specific incorporation of a non-canonical amino acid
Schoherr_2008_Eur.J.Med.Genet_51_322No evidence for isolated imprinting mutations in the PEG1/MEST locus in Silver-Russell patients
Scholey_2008_Psychopharmacology.(Berl)_198_127An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers
Schreck_2008_Chemosphere_71_1832Neurotoxic effect and metabolic responses induced by a mixture of six pesticides on the earthworm Aporrectodea caliginosa nocturna
Schuler_2008_Appl.Environ.Microbiol_74_1050Characterization of a novel angular dioxygenase from fluorene-degrading Sphingomonas sp. strain LB126
Schutz_2008_Neurosci_156_310Sweat gland innervation is pioneered by sympathetic neurons expressing a cholinergic/noradrenergic co-phenotype in the mouse
Schweiger_2008_J.Biol.Chem_283_17211The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding
Schwelm_2008_Mycol.Res_112_138Early expression of aflatoxin-like dothistromin genes in the forest pathogen Dothistroma septosporum
Scipione_2008_Bioorg.Med.Chem.Lett_18_3094-Aminopyridine derivatives with anticholinesterase and antiamnesic activity
Scott_2008_J.Pestic.Sci_33_221Unraveling the mystery of spinosad resistance in insects
Searl_2008_J.Neurophysiol_99_2779Mechanisms of neuromodulation as dissected using Sr2+ at motor nerve endings
Secundo_2008_Biotechnol.Bioeng_101_255Role of methoxypolyethylene glycol on the hydration, activity, conformation and dynamic properties of a lipase in a dry film
Seedorf_2008_Proc.Natl.Acad.Sci.U.S.A_105_2128The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features
Sega_2008_Clin.Chim.Acta_389_177New organophosphorus compounds: cholinesterases inhibition, cytotoxicity and lethal dose
Sekiya_2008_J.Lipid.Res_49_1829Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
Sela_2008_Proc.Natl.Acad.Sci.U.S.A_105_18964The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome
Selek_2008_Clin.Biochem_41_140PON1 activity and total oxidant status in patients with active pulmonary tuberculosis
Sellings_2008_Eur.J.Neurosci_28_342Rewarding and aversive effects of nicotine are segregated within the nucleus accumbens
Semba_2008_Appl.Microbiol.Biotechnol_79_563Efficient production of active form of recombinant cassava hydroxynitrile lyase using Escherichia coli in low-temperature culture
Semba_2008_Biosci.Biotechnol.Biochem_72_1457Expression of hydroxynitrile lyase from Manihot esculenta in yeast and its application in (S)-mandelonitrile production using an immobilized enzyme reactor
Semmler_2008_Front.Zool_5_14Myogenesis in the basal bilaterian Symsagittifera roscoffensis (Acoela)
Senthil_2008_Ecotoxicol.Environ.Saf_70_244Effect of azadirachtin on acetylcholinesterase (AChE) activity and histology of the brown planthopper Nilaparvata lugens (Stal)
Seok_2008_Ecotoxicol.Environ.Saf_71_245Risk assessment of the organophosphate pesticides isazofos and pyraclofos using a 21-day dietary toxicity study in Japanese quail
Serra_2008_Int.J.Clin.Pharmacol.Ther_46_349Evaluation of pharmacokinetic and pharmacodynamic interaction between the dipeptidyl peptidase IV inhibitor vildagliptin, glyburide and pioglitazone in patients with Type 2 diabetes
Serruys_2008_Circulation_118_1172Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque
Shafferman_2008_Chem.Biol.Interact_175_166Flexibility versus rigidity of the functional architecture of AChE active center
Shah_2008_Biomed.Pharmacother_62_199Current approaches in the treatment of Alzheimer's disease
Shah_2008_Biotechnol.Adv_26_246Biological degradation of plastics: a comprehensive review
Shaked_2008_Ann.N.Y.Acad.Sci_1148_269Stress-induced alternative splicing modulations in brain and periphery: acetylcholinesterase as a case study
Shan_2008_J.Anim.Sci_86_1781Porcine adipose triglyceride lipase complementary deoxyribonucleic acid clone, expression pattern, and regulation by resveratrol
Shankle_2008_Neurol.Res_30_313Omentum transposition surgery for patients with Alzheimer's disease: a case series
Shao_2008_J.Neurosci_28_519Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic/nicotinic modulation of respiratory rhythm
Shapira-Lichter_2008_Brain.Behav.Immun_22_388Cytokines and cholinergic signals co-modulate surgical stress-induced changes in mood and memory
Shariat_2008_Can.J.Urol_15_4363Screening for prostate cancer: an update
Sharma_2008_Curr.Med.Chem_15_2921Nicotinic receptors containing the alpha7 subunit: a model for rational drug design
Sharma_2008_J.Neurosci_28_2563Action potential-independent and nicotinic receptor-mediated concerted release of multiple quanta at hippocampal CA3-mossy fiber synapses
Sharma_2008_J.Psychopharmacol_22_162Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by pitavastatin and donepezil
Sharma_2008_Pharmacol.Biochem.Behav_89_535Exploitation of HIV protease inhibitor Indinavir as a memory restorative agent in experimental dementia
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Wierdl_2008_Cancer.Gene.Ther_15_183An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11
Wijekoon_2008_Funct.Plant.Biol_35_1112The involvement of two epoxide hydrolase genes, NbEH1.1 and NbEH1.2, of Nicotiana benthamiana in the interaction with Colletotrichum destructivum, Colletotrichum orbiculare or Pseudomonas syringae pv. tabaci.
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Wilensky_2008_Nat.Med_14_1059Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
Williams-Herman_2008_BMC.Endocr.Disord_8_14Safety and tolerability of sitagliptin in patients with type 2 diabetes: a pooled analysis
Williams_2008_Drug.Metab.Dispos_36_1227The biotransformation of prasugrel, a new thienopyridine prodrug, by the human carboxylesterases 1 and 2
Williams_2008_J.Pharmacol.Toxicol.Methods_57_138Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases
Williams_2008_Risk.Anal_28_1069Modeling cholinesterase activity for human dietary risk assessment of carbamate insecticides
Wills_2008_Neurology_70_929Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS
Wilson-Grady_2008_J.Proteome.Res_7_1088Phosphoproteome analysis of fission yeast
Wilson_2008_Brain.Res_1200_159Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
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Wise_2008_Neuropharmacol_54_181Evaluation of fatty acid amides in the carrageenan-induced paw edema model
Wogulis_2008_Biochemistry_47_1608Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence
Wolf_2008_J.Neurochem_107_96Neurturin, a member of the glial cell line-derived neurotrophic factor family, affects the development of acetylcholinesterase-positive cells in a three-dimensional model system of retinogenesis
Wonnacott_2008_Br.J.Pharmacol_153 Suppl 1_S2Gates and filters: unveiling the physiological roles of nicotinic acetylcholine receptors in dopaminergic transmission
Wonnacott_2008_IDrugs_11_256Smoking cessation 2008
Woo_2008_Protein.Sci_17_725Structure-function studies on the active site of the coelenterazine-dependent luciferase from Renilla
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Woods_2008_BMC.Biotechnol_8_95Hairy-root organ cultures for the production of human acetylcholinesterase
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Wright_2008_Atherosclerosis_199_187Genetic screening of the LPL gene in hypertriglyceridaemic patients
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Wu_2008_J.Med.Invest_55_61NO-1886, a lipoprotein lipase activator, attenuates contraction of rat intestinal ring preparations
Wu_2008_Lipids_43_733Hepatic lipase gene -514C/T polymorphism in the Guangxi Hei Yi Zhuang and Han populations
Wu_2008_Mol.Pharmacol_74_466Morantel allosterically enhances channel gating of neuronal nicotinic acetylcholine alpha 3 beta 2 receptors
Wu_2008_Planta_227_1161Methyl jasmonate-elicited herbivore resistance: does MeJA function as a signal without being hydrolyzed to JA?
Wu_2008_Se.Pu_26_577[A rapid multi-residual analysis for organophosphorus pesticides in the products of animal origin using gas chromatography coupled with accelerated solvent extraction and gel permeation chromatographic purification]
Xia_2008_Insect.Biochem.Mol.Biol_38_1036The genome of a lepidopteran model insect, the silkworm Bombyx mori
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Xie_2008_FEMS.Microbiol.Lett_289_181Esterase SeE of Streptococcus equi ssp. equi is a novel nonspecific carboxylic ester hydrolase
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Xie_2008_Phytochemistry_69_427Isolation and identification of alectrol as (+)-orobanchyl acetate, a germination stimulant for root parasitic plants
Xing_2008_Cell_133_154Structural mechanism of demethylation and inactivation of protein phosphatase 2A
Xiong_2008_Exp.Neurol_211_271Doublecortin-expressing cells are present in layer II across the adult guinea pig cerebral cortex: partial colocalization with mature interneuron markers
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Xu_2008_Appl.Microbiol.Biotechnol_81_79Heterologous expression of lipase in Escherichia coli is limited by folding and disulfide bond formation
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Xu_2008_J.Mol.Biol_375_708Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism
Xu_2008_Neurosci_155_403Polymorphisms of the lipoprotein lipase gene are associated with atherosclerotic cerebral infarction in the Chinese
Xu_2008_PLoS.ONE_3_E1450Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of serotype 3 prevalent in China
Xu_2008_Protein.Sci_17_601Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design
Xu_2008_Sci.Total.Environ_393_333Occurrence and degradation characteristics of dibutyl phthalate (DBP) and di-(2-ethylhexyl) phthalate (DEHP) in typical agricultural soils of China
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Yamamoto_2008_Org.Biomol.Chem_6_1540Enzymatic resolution and evaluation of enantiomers of cis-5'-hydroxythalidomide
Yamamoto_2008_Plant.Signal.Behav_3_576Subcellular localization of overexpressed maize AChE gene in rice plant
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Yan_2008_Am.J.Obstet.Gynecol_198_229 e1The effect of esterases on 17alpha-hydroxyprogesterone caproate
Yan_2008_Appl.Microbiol.Biotechnol_78_431Optimization for producing cell-bound lipase from Geotrichum sp. and synthesis of methyl oleate in microaqueous solvent
Yan_2008_J.Econ.Entomol_101_1897Dynamics of esterase alleles in Culex pipiens complex mosquitoes in Beijing
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Yang_2008_J.Environ.Sci.Health.B_43_219Hydrolysis and soil sorption of insecticide pyraclofos
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Yang_2008_Plant.Physiol_147_1034Inactive methyl indole-3-acetic acid ester can be hydrolyzed and activated by several esterases belonging to the AtMES esterase family of Arabidopsis
Yang_2008_Toxicol.Appl.Pharmacol_228_32Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase
Yang_2008_Toxicon_51_289A phospholipase A1 platelet activator from the wasp venom of Vespa magnifica (Smith)
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Yao_2008_Acta.Biochim.Biophys.Sin.(Shanghai)_40_625NDRG2: a Myc-repressed gene involved in cancer and cell stress
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Yazbeck_2008_Front.Biosci_13_6850Inhibiting dipeptidyl peptidase activity partially ameliorates colitis in mice
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Yeo_2008_J.Biomed.Mater.Res.B.Appl.Biomater_87_562Customizing the degradation and load-bearing profile of 3D polycaprolactone-tricalcium phosphate scaffolds under enzymatic and hydrolytic conditions
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Yildiz_2008_Atherosclerosis_197_257Association of paraoxonase activity and coronary blood flow
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Yoneyama_2008_New.Phytol_179_484Strigolactones, host recognition signals for root parasitic plants and arbuscular mycorrhizal fungi, from Fabaceae plants
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Yu_2008_J.Biosci.Bioeng_106_65Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups
Yu_2008_J.Ethnopharmacol_119_252Inhibition of Coix seed extract on fatty acid synthase, a novel target for anticancer activity
Yu_2008_J.Pharm.Biomed.Anal_46_75The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine
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Yu_2008_World.J.Pediatr_4_8Glucagon-like peptide 1 based therapy for type 2 diabetes
Yuan_2008_J.Nutr.Sci.Vitaminol.(Tokyo)_54_185Gene identification and characterization of the pyridoxine degradative enzyme alpha-(N-acetylaminomethylene)succinic acid amidohydrolase from Mesorhizobium loti MAFF303099
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Zahodne_2008_CNS.Spectr_13_26Course, prognosis, and management of psychosis in Parkinson's disease: are current treatments really effective?
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Zawisza-Raszka_2008_Acta.Biol.Hung_59_31Acetylcholinesterase, catalase and glutathione S-transferase activity in beet armyworm (Spodoptera exigua) exposed to nickel and/or diazinon
Zeljezic_2008_Basic.Clin.Pharmacol.Toxicol_103_329Cholinesterase-inhibiting and genotoxic effects of acute carbofuran intoxication in man: a case report
Zeng_2008_Appl.Microbiol.Biotechnol_80_899Biodegradation of dimethyl phthalate by Sphingomonas sp. isolated from phthalic-acid-degrading aerobic granules
Zhai_2008_J.Proteome.Res_7_1675Phosphoproteome analysis of Drosophila melanogaster embryos
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Zhang_2008_Biomed.Chromatogr_22_414Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry
Zhang_2008_Bioorg.Med.Chem.Lett_18_5753Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release
Zhang_2008_Cell.Mol.Life.Sci_65_1435The JNK/AP1/ATF2 pathway is involved in H2O2-induced acetylcholinesterase expression during apoptosis
Zhang_2008_Cell.Mol.Neurobiol_28_173Non-cholinergic effects of huperzine A: beyond inhibition of acetylcholinesterase
Zhang_2008_Chem.Biol.Interact_175_396Potential therapeutic targets of huperzine A for Alzheimer's disease and vascular dementia
Zhang_2008_Circ.Res_102_250Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet
Zhang_2008_Gene_417_5Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter region
Zhang_2008_J.Environ.Sci.(China)_20_364Influences of Cu or Cd on the neurotoxicity induced by petroleum hydrocarbons in ragworm Perinereis aibuhitensis
Zhang_2008_J.Nutr_138_515Lipid metabolism in diet-induced obese rabbits is similar to that of obese humans
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Zhang_2008_Pest.Manag.Sci_64_185Inheritance of beta-cypermethrin resistance in the housefly Musca domestica (Diptera: Muscidae)
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Zhang_2008_Protein.Pept.Lett_15_1132Predicting lipase types by improved Chou's pseudo-amino acid composition
Zhang_2008_Stroke_39_2073Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia
Zhang_2008_Toxicology_248_136Permethrin may induce adult male mouse reproductive toxicity due to cis isomer not trans isomer
Zhang_2008_World.J.Pediatr_4_295Diagnosis and surgical treatment of isolated hypoganglionosis
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Zhao_2008_J.Ind.Microbiol.Biotechnol_35_189Scale-up fermentation of recombinant Candida rugosa lipase expressed in Pichia pastoris using the GAP promoter
Zhao_2008_J.Pestic.Sci_33_371Design of novel carbamate acetylcholinesterase inhibitors based on the multiple binding sites of acetylcholinesterase
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Zheng_2008_J.Am.Chem.Soc_130_12148Most efficient cocaine hydrolase designed by virtual screening of transition states
Zheng_2008_J.Comput.Aided.Mol.Des_22_661Rational design of an enzyme mutant for anti-cocaine therapeutics
Zheng_2008_Org.Biomol.Chem_6_836Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction
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Zhou_2008_Bioorg.Med.Chem_16_8011Design, synthesis, and acetylcholinesterase inhibitory activity of novel coumarin analogues
Zhou_2008_Chem.Commun.(Camb)__5806Epoxy functionalised poly(epsilon-caprolactone): synthesis and application
Zhou_2008_J.Agric.Food.Chem_56_2708Preparation, stabilization, and bioefficacy of beta-cyclodextrin inclusion compounds of chloramidophos
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Zhu_2008_Am.J.Hum.Genet_82_1241Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis
Zhu_2008_Clin.Chem_54_705Effect of (R)-salsolinol and N-methyl-(R)-salsolinol on the balance impairment between dopamine and acetylcholine in rat brain: involvement in pathogenesis of Parkinson disease
Zhu_2008_Sleep_31_1629Morphine increases acetylcholine release in the trigeminal nuclear complex
Zhu_2008_Talanta_74_1579Quantitative analysis of hydrolysis of carbaryl in tap water and river by excitation-emission matrix fluorescence coupled with second-order calibration
Zhu_2008_Yao.Xue.Xue.Bao_43_267Construction of the pharmacophore model of acetylcholinesterase inhibitor
Zimin_2008_Bioinformatics_24_42Assembly reconciliation
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Zimmermann_2008_J.Neurochem_104_221Selective enhancement of the activity of C-terminally truncated, but not intact, acetylcholinesterase
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Zisimopoulou_2008_J.Neuroimmunol_201-202_95Towards antigen-specific apheresis of pathogenic autoantibodies as a further step in the treatment of myasthenia gravis by plasmapheresis
Zivin_2008_Psychiatr.Danub_20_168Prolonged treatment with donepezil increases acetylcholinesterase expression in the central nervous system
Zolese_2008_Biofactors_33_201Effect of acylethanolamides on lipid peroxidation and paraoxonase activity
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Zullo_2008_Food.Microbiol_25_970Lipolytic yeasts distribution in commercial extra virgin olive oil
Zutter_2008_J.Org.Chem_73_4895New, efficient synthesis of oseltamivir phosphate (Tamiflu) via enzymatic desymmetrization of a meso-1,3-cyclohexanedicarboxylic acid diester
Zvonok_2008_Chem.Biol_15_854Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis
Zvonok_2008_J.Proteome.Res_7_2158Full mass spectrometric characterization of human monoacylglycerol lipase generated by large-scale expression and single-step purification
Zwart_2008_Mol.Pharmacol_73_1838Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors
da Fonseca_2008_Ecotoxicol.Environ.Saf_69_416The 2,4-D herbicide effects on acetylcholinesterase activity and metabolic parameters of piava freshwater fish (Leporinus obtusidens)
da Silva-Lopez_2008_Acta.Trop_107_159Purification and subcellular localization of a secreted 75 kDa Trypanosoma cruzi serine oligopeptidase
da Silva_2008_Int.J.Dev.Neurosci_26_339Maternal caffeine intake affects acetylcholinesterase in hippocampus of neonate rats
da Silva_2008_Neurotoxicol_29_184Temporal effects of newly developed oximes (K027, K048) on malathion-induced acetylcholinesterase inhibition and lipid peroxidation in mouse prefrontal cortex
da Silva_2008_Physiol.Behav_95_88Serotonin receptors contribute to the promnesic effects of P. olacoides (Marapuama)
de Geus_2008_Biomacromolecules_9_752Insights into the initiation process of enzymatic ring-opening polymerization from monofunctional alcohols using liquid chromatography under critical conditions
de Lima Portella_2008_Life.Sci_83_878Oximes as inhibitors of low density lipoprotein oxidation
de Melo_2008_Ecotoxicol.Environ.Saf_71_821Hepatic alterations in the fish Rhamdia quelen contaminated with Folidol 600(R)
de Oliveira_2008_Clin.Hemorheol.Microcirc_39_363Modulation of erythrocyte deformability by PKC activity
de Pascale_2008_Extremophiles_12_311The cold-active Lip1 lipase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 is a member of a new bacterial lipolytic enzyme family
de Zwart_2008_Reprod.Toxicol_26_220The ontogeny of drug metabolizing enzymes and transporters in the rat
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van Acker_2008_Atherosclerosis_200_161High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants
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van Deursen_2008_Mol.Cell.Endocrinol_294_37Down-regulation of hepatic lipase expression by elevation of cAMP in human hepatoma but not adrenocortical cells
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Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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