2008

Mayumi_2008_Appl.Microbiol.Biotechnol_79_743 Identification and characterization of novel poly(DL-lactic acid) depolymerases from metagenome
Chu_2008_Mycol.Res_112_1421 Identification and characterization of a lipase gene from Antrodia cinnamomea
Yao_2008_Mol.Biotechnol_38_99 Isolation of a novel lipase gene from Serratia liquefaciens S33 DB-1, functional expression in Pichia pastoris and its properties
de Pascale_2008_Extremophiles_12_311 The cold-active Lip1 lipase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 is a member of a new bacterial lipolytic enzyme family
Opperman_2008_Proc.Natl.Acad.Sci.U.S.A_105_14802 Sequence and genetic map of Meloidogyne hapla: A compact nematode genome for plant parasitism
Moukouli_2008_Appl.Microbiol.Biotechnol_79_245 Cloning, characterization and functional expression of an alkalitolerant type C feruloyl esterase from Fusarium oxysporum
Chou_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_1118 Crystallization and preliminary X-ray diffraction analysis of phospholipase A1 isolated from hornet (Vespa basalis) venom
Martinez_2008_Nat.Biotechnol_26_553 Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina)
Hunsen_2008_Biomacromolecules_9_518 Humicola insolens cutinase-catalyzed lactone ring-opening polymerizations: kinetic and mechanistic studies
Miyauchi_2008_J.Biosci.Bioeng_105_628 Isolation of dibenzofuran-degrading bacterium, Nocardioides sp. DF412, and characterization of its dibenzofuran degradation genes
Li_2008_J.Biol.Chem_283_28607 Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis
Konstantinidis_2008_ISME.J_2_1052 Genomic patterns of recombination, clonal divergence and environment in marine microbial populations
Martin-Cuadrado_2008_ISME.J_2_865 Hindsight in the relative abundance, metabolic potential and genome dynamics of uncultivated marine archaea from comparative metagenomic analyses of bathypelagic plankton of different oceanic regions
Morissette_2008_Curr.Genet_53_67 Isolation of mycoparasitic-related transcripts by SSH during interaction of the mycoparasite Stachybotrys elegans with its host Rhizoctonia solani
Hu_2008_J.Bacteriol_190_2892 Complete genome sequence of the mosquitocidal bacterium Bacillus sphaericus C3-41 and comparison with those of closely related Bacillus species
Lapidus_2008_Chem.Biol.Interact_171_236 Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity
Gillings_2008_J.Bacteriol_190_5095 The evolution of class 1 integrons and the rise of antibiotic resistance
Welsh_2008_Proc.Natl.Acad.Sci.U.S.A_105_15094 The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium important in the marine nitrogen cycle
Denker_2008_Chem.Biol.Interact_175_125 Acetylcholinesterase activity in Clytia hemisphaerica (Cnidaria)
Fu_2008_Enzyme.Microb.Technol_42_187 A novel cold-adapted phospholipase A(1) from Serratia sp. xjF1: Gene cloning, expression and characterization
Gonzalez_2008_Proc.Natl.Acad.Sci.U.S.A_105_8724 Genome analysis of the proteorhodopsin-containing marine bacterium Polaribacter sp. MED152 (Flavobacteria)
Jung_2008_Proteins_71_476 Structural basis for the cold adaptation of psychrophilic M37 lipase from Photobacterium lipolyticum
Janssen_2008_Dev.Genes.Evol_218_361 Evidence for Wg-independent tergite boundary formation in the millipede Glomeris marginata
Ren_2008_Pestic.Biochem.Physiol_90_196 Comparison of acetylcholinesterase from three field populations of Liposcelis paeta Pearman (Psocoptera: Liposcelididae): Implications of insecticide resistance
Kuntz_2008_Genome.Res_18_1955 Multigenome DNA sequence conservation identifies Hox cis-regulatory elements
Kang_2008_J.Microbiol.Biotechnol_18_1445 A cold-adapted epoxide hydrolase from a strict marine bacterium, Sphingophyxis alaskensis
Li_2008_Microb.Cell.Fact_7_38 Molecular cloning and characterization of a novel pyrethroid-hydrolyzing esterase originating from the Metagenome
Swingley_2008_Proc.Natl.Acad.Sci.U.S.A_105_2005 Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina
Iacono_2008_Antimicrob.Agents.Chemother_52_2616 Whole-genome pyrosequencing of an epidemic multidrug-resistant Acinetobacter baumannii strain belonging to the European clone II group
Adams_2008_J.Bacteriol_190_8053 Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii
Vallenet_2008_PLoS.ONE_3_E1805 Comparative analysis of Acinetobacters: three genomes for three lifestyles
Reysenbach_2008_Geobiology_6_331 Electron microscopy encounters with unusual thermophiles helps direct genomic analysis of Aciduliprofundum boonei
Valdes_2008_BMC.Genomics_9_597 Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications
Foote_2008_J.Bacteriol_190_1495 The complete genome sequence of Actinobacillus pleuropneumoniae L20 (serotype 5b)
Xu_2008_PLoS.ONE_3_E1450 Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of serotype 3 prevalent in China
Gladyshev_2008_Science_320_1210 Massive horizontal gene transfer in bdelloid rotifers
Kiss_2008_J.Struct.Biol_162_312 Structural and kinetic contributions of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase
Reith_2008_BMC.Genomics_9_427 The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen
Gross_2008_BMC.Genomics_9_449 The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae
Jencova_2008_Res.Microbiol_159_118 Nucleotide sequence, organization and characterization of the (halo)aromatic acid catabolic plasmid pA81 from Achromobacter xylosoxidans A8
Mandrich_2008_Proteins_71_1721 Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius
Febbraio_2008_Extremophiles_12_719 Irreversible inhibition of the thermophilic esterase EST2 from Alicyclobacillus acidocaldarius
Kozaki_2008_Arch.Insect.Biochem.Physiol_67_130 Comparison of two acetylcholinesterase gene cDNAs of the lesser mealworm, Alphitobius diaperinus, in insecticide susceptible and resistant strains
Ivars-Martinez_2008_ISME.J_2_1194 Comparative genomics of two ecotypes of the marine planktonic copiotroph Alteromonas macleodii suggests alternative lifestyles associated with different kinds of particulate organic matter
Saw_2008_Genome.Biol_9_R161 Encapsulated in silica: genome, proteome and physiology of the thermophilic bacterium Anoxybacillus flavithermus WK1
Carlier_2008_Chem.Biol.Interact_175_368 Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae
Biswas_2008_PLoS.ONE_3_E3542 Bridging the synaptic gap: neuroligins and neurexin I in Apis mellifera
Mackert_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_33 Identification of a juvenile hormone esterase-like gene in the honey bee, Apis mellifera L.--expression analysis and functional assays
Oyama_2008_Plant.Syst.Evol_273_257 The shrunken genome of Arabidopsis thaliana.
Yang_2008_Plant.Physiol_147_1034 Inactive methyl indole-3-acetic acid ester can be hydrolyzed and activated by several esterases belonging to the AtMES esterase family of Arabidopsis
Hyun_2008_Dev.Cell_14_183 Cooperation and functional diversification of two closely related galactolipase genes for jasmonate biosynthesis
Huizinga_2008_Plant.Cell_20_2714 Isoprenylcysteine methylation and demethylation regulate abscisic acid signaling in Arabidopsis
Vlot_2008_Plant.J_56_445 Identification of likely orthologs of tobacco salicylic acid-binding protein 2 and their role in systemic acquired resistance in Arabidopsis thaliana
Murase_2008_Nature_456_459 Gibberellin-induced DELLA recognition by the gibberellin receptor GID1
Fedorova_2008_PLoS.Genet_4_E1000046 Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus
Crawford_2008_Science_320_243 Deconstruction of iterative multidomain polyketide synthase function
Arakawa_2008_J.Antibiot.(Tokyo)_61_442 A new terrein glucoside, a novel inhibitor of angiogenin secretion in tumor angiogenesis
Lee_2008_J.Endod_34_433 Terrein reduces pulpal inflammation in human dental pulp cells
Sanchez-Otero_2008_J.Ind.Microbiol.Biotechnol_35_1687 Immobilization in the presence of Triton X-100: modifications in activity and thermostability of Geobacillus thermoleovorans CCR11 lipase
Halami_2008_World.J.Microbiol.Biotechnol_24_805 Production of polyhydroxyalkanoate from starch by the native isolate Bacillus cereus CFR06.
Boersma_2008_Chem.Biol_15_782 Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity
Ahmad_2008_J.Mol.Biol_381_324 Thermostable Bacillus subtilis lipases: in vitro evolution and structural insight
Rajakumara_2008_Biochim.Biophys.Acta_1784_302 Structural basis for the remarkable stability of Bacillus subtilis lipase (Lip A) at low pH
Kourist_2008_Chembiochem_9_67 Understanding promiscuous amidase activity of an esterase from Bacillus subtilis
Bartsch_2008_Angew.Chem.Int.Ed.Engl_47_1508 Complete inversion of enantioselectivity towards acetylated tertiary alcohols by a double mutant of a Bacillus subtilis esterase
Koglin_2008_Nature_454_907 Structural basis for the selectivity of the external thioesterase of the surfactin synthetase
Tanovic_2008_Science_321_659 Crystal structure of the termination module of a nonribosomal peptide synthetase
Fernandez-Lorente_2008_Biomacromolecules_9_2553 Solid-phase chemical amination of a lipase from Bacillus thermocatenulatus to improve its stabilization via covalent immobilization on highly activated glyoxyl-agarose
Carrasco-Lopez_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_1043 Crystallization and preliminary X-ray diffraction studies of the BTL2 lipase from the extremophilic microorganism Bacillus thermocatenulatus
Alon_2008_Insect.Biochem.Mol.Biol_38_940 Organophosphates' resistance in the B-biotype of Bemisia tabaci (Hemiptera: Aleyrodidae) is associated with a point mutation in an ace1-type acetylcholinesterase and overexpression of carboxylesterase
Lee_2008_BMC.Genomics_9_247 Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth
Sela_2008_Proc.Natl.Acad.Sci.U.S.A_105_18964 The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome
Xia_2008_Insect.Biochem.Mol.Biol_38_1036 The genome of a lepidopteran model insect, the silkworm Bombyx mori
Guerrero_2008_J.Med.Entomol_45_677 Gene structure and expression of a pyrethroid-metabolizing esterase, CzEst9, from a pyrethroid resistant Mexican population of Rhipicephalus (Boophilus) microplus (Acari: Ixodidae)
Holmes_2008_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_3_195 Mammalian carboxylesterase 5: comparative biochemistry and genomics
Putnam_2008_Nature_453_1064 The amphioxus genome and the evolution of the chordate karyotype
Weier_2008_Planta_227_375 The genes BnSCT1 and BnSCT2 from Brassica napus encoding the final enzyme of sinapine biosynthesis: molecular characterization and suppression
Chen_2008_Plant.Sci_174_25 Transgenic broccoli (Brassica oleracea var. italica) with antisense chlorophyllase (BoCLH1) delays postharvest yellowing.
Crasta_2008_PLoS.ONE_3_E2193 Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes
Foster_2008_J.Clin.Microbiol_46_296 Real-time PCR assays of single-nucleotide polymorphisms defining the major Brucella clades
Dalal_2008_Biotechnol.Appl.Biochem_51_23 Purification and properties of the alkaline lipase from Burkholderia cepacia A.T.C.C. 25609
Luic_2008_J.Phys.Chem.B_112_4876 Combined X-ray diffraction and QM\/MM study of the Burkholderia cepacia lipase-catalyzed secondary alcohol esterification
Wang_2008_Science_322_957 Fat metabolism links germline stem cells and longevity in C. elegans
Harris_2008_Arch.Biochem.Biophys_472_139 Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules
Cutter_2008_Genetics_178_1661 Multilocus patterns of polymorphism and selection across the X chromosome of Caenorhabditis remanei
Miller_2008_Foodborne.Pathog.Dis_5_371 The complete genome sequence and analysis of the human pathogen Campylobacter lari
Takwa_2008_Biomacromolecules_9_704 Lipase catalyzed HEMA initiated ring-opening polymerization: in situ formation of mixed polyester methacrylates by transesterification
Reetz_2008_Chem.Commun.(Camb)__5502 A genetic selection system for evolving enantioselectivity of enzymes
Chen_2008_Biomacromolecules_9_463 Candida antarctica lipase B chemically immobilized on epoxy-activated micro- and nanobeads: catalysts for polyester synthesis
Ericsson_2008_J.Mol.Biol_376_109 X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation
Brandt_2008_Acta.Crystallogr.A.Found.Crystallogr_64_C245 The crystal structure of lipase a from Candida Antarctica
Turner_2008_Mol.Ecol_17_2616 Reproductive protein evolution within and between species: maintenance of divergent ZP3 alleles in Peromyscus
DeBoy_2008_J.Bacteriol_190_5455 Insights into plant cell wall degradation from the genome sequence of the soil bacterium Cellvibrio japonicus
Lejon_2008_J.Mol.Biol_377_935 The last step in cephalosporin C formation revealed: crystal structures of deacetylcephalosporin C acetyltransferase from Acremonium chrysogenum in complexes with reaction intermediates
Magana_2008_Insect.Biochem.Mol.Biol_38_756 Mechanisms of resistance to malathion in the medfly Ceratitis capitata
Saarela_2008_BMC.Genomics_9_281 The patatin-like lipase family in Gallus gallus
Thomson_2008_Genome.Res_18_161 Chlamydia trachomatis: genome sequence analysis of lymphogranuloma venereum isolates
Frederick_2008_Febs.J_275_1309 Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide
Gartemann_2008_J.Bacteriol_190_2138 The genome sequence of the tomato-pathogenic actinomycete Clavibacter michiganensis subsp. michiganensis NCPPB382 reveals a large island involved in pathogenicity
Bentley_2008_J.Bacteriol_190_2150 Genome of the actinomycete plant pathogen Clavibacter michiganensis subsp. sepedonicus suggests recent niche adaptation
Seedorf_2008_Proc.Natl.Acad.Sci.U.S.A_105_2128 The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features
Nyon_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_504 Crystallization and preliminary X-ray analysis of recombinant Glomerella cingulata cutinase
Letek_2008_J.Bacteriol_190_5797 Evolution of the Rhodococcus equi vap pathogenicity island seen through comparison of host-associated vapA and vapB virulence plasmids
Tauch_2008_J.Biotechnol_136_11 The lifestyle of Corynebacterium urealyticum derived from its complete genome sequence established by pyrosequencing
Tauch_2008_J.Biotechnol_136_22 Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids
Mondego_2008_BMC.Genomics_9_548 A genome survey of Moniliophthora perniciosa gives new insights into Witches' Broom Disease of cacao
Amadou_2008_Genome.Res_18_1472 Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia
Kneip_2008_BMC.Evol.Biol_8_30 The cyanobacterial endosymbiont of the unicellular algae Rhopalodia gibba shows reductive genome evolution
Bakthavatsalam_2008_J.Cell.Sci_121_2473 The secreted Dictyostelium protein CfaD is a chalone
Sillo_2008_BMC.Genomics_9_291 Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium
Calvo-Garrido_2008_Mol.Biol.Cell_19_3442 Vacuole membrane protein 1 is an endoplasmic reticulum protein required for organelle biogenesis, protein secretion, and development
Zimin_2008_Bioinformatics_24_42 Assembly reconciliation
Bannan_2008_Fly.(Austin)_2_198 The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases
Leung_2008_Neuron_58_884 DAG lipase activity is necessary for TRP channel regulation in Drosophila photoreceptors
Kohn_2008_Genes.Genet.Syst_83_265 Decoupled differentiation of gene expression and coding sequence among Drosophila populations
Rasko_2008_J.Bacteriol_190_6881 The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates
Durfee_2008_J.Bacteriol_190_2597 The complete genome sequence of Escherichia coli DH10B: insights into the biology of a laboratory workhorse
Oshima_2008_DNA.Res_15_375 Complete genome sequence and comparative analysis of the wild-type commensal Escherichia coli strain SE11 isolated from a healthy adult
Fricke_2008_J.Bacteriol_190_6779 Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5
Frueh_2008_Nature_454_903 Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase
Li_2008_Chembiochem_9_71 Catalytic promiscuity in the alpha\/beta-hydrolase superfamily: hydroxamic acid formation, C--C bond formation, ester and thioester hydrolysis in the C--C hydrolase family
Kadlec_2008_J.Antimicrob.Chemother_62_469 Analysis and distribution of class 1 and class 2 integrons and associated gene cassettes among Escherichia coli isolates from swine, horses, cats and dogs collected in the BfT-GermVet monitoring study
Enne_2008_FEMS.Microbiol.Lett_278_193 A high prevalence of antimicrobial resistant Escherichia coli isolated from pigs and a low prevalence of antimicrobial resistant E. coli from cattle and sheep in Great Britain at slaughter
Park_2008_J.Mol.Biol_376_1426 High-resolution structure of ybfF from Escherichia coli K12: a unique substrate-binding crevice generated by domain arrangement.
Jiang_2008_Biochemistry_47_3426 Identification and characterization of (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase in the menaquinone biosynthesis of Escherichia coli
Ogura_2008_J.Bacteriol_190_6948 Systematic identification and sequence analysis of the genomic islands of the enteropathogenic Escherichia coli strain B171-8 by the combined use of whole-genome PCR scanning and fosmid mapping
Kim_2008_Antimicrob.Agents.Chemother_52_606 Complete DNA sequence and analysis of the transferable multiple-drug resistance plasmids (R Plasmids) from Photobacterium damselae subsp. piscicida isolates collected in Japan and the United States
Bourgogne_2008_Genome.Biol_9_R110 Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF
Kube_2008_Environ.Microbiol_10_2211 The genome of Erwinia tasmaniensis strain Et1\/99, a non-pathogenic bacterium in the genus Erwinia
Raymond_2008_Extremophiles_12_713 A bacterial ice-binding protein from the Vostok ice core
Matsumura_2008_Proteins_70_592 Novel cation-pi interaction revealed by crystal structure of thermoalkalophilic lipase
Sun_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_813 Crystallization and preliminary crystallographic analysis of Gibberella zeae extracellular lipase
O'Donnell_2008_Fungal.Genet.Biol_45_1514 Multilocus genotyping and molecular phylogenetics resolve a novel head blight pathogen within the Fusarium graminearum species complex from Ethiopia
Temeyer_2008_Vet.Parasitol_154_300 Acetylcholinesterase mutation in diazinon-resistant Haematobia irritans (L.) (Diptera: Muscidae)
Lu_2008_J.Bacteriol_190_4173 Genetic and biochemical characterization of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate) synthase in Haloferax mediterranei
Pfeiffer_2008_Genomics_91_335 Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1
Wee_2008_Insect.Mol.Biol_17_351 Identification of candidate genes for fenvalerate resistance in Helicoverpa armigera using cDNA-AFLP
Schmidt_2008_J.Biol.Chem_283_21827 Atomic resolution crystal structures and quantum chemistry meet to reveal subtleties of hydroxynitrile lyase catalysis
Miyata_2008_Biochem.Biophys.Res.Commun_365_207 Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque
Liu_2008_Neuropharmacol_54_1 Multiple pathways involved in the biosynthesis of anandamide
Ghosh_2008_J.Biol.Chem_283_24525 CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid
Lai_2008_J.Biol.Chem_283_9318 Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase
Carletti_2008_J.Am.Chem.Soc_130_16011 Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
Vesterhus_2008_Diabetes.Care_31_306 Pancreatic exocrine dysfunction in maturity-onset diabetes of the young type 3
Vesterhus_2008_Diabetes.Care_31_1738 Neurological features and enzyme therapy in patients with endocrine and exocrine pancreas dysfunction due to CEL mutations
Zhu_2008_Am.J.Hum.Genet_82_1241 Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis
Zhao_2008_J.Lipid.Res_49_2212 Hepatic overexpression of cholesteryl ester hydrolase enhances cholesterol elimination and in vivo reverse cholesterol transport
Crow_2008_Biochim.Biophys.Acta_1781_643 Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte\/macrophages
Fukami_2008_Pharmacogenet.Genomics_18_911 Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes
Yoshimura_2008_Biochem.Biophys.Res.Commun_369_939 Functional polymorphisms in carboxylesterase1A2 (CES1A2) gene involves specific protein 1 (Sp1) binding sites
Hosokawa_2008_Drug.Metab.Pharmacokinet_23_73 Structural organization and characterization of the regulatory element of the human carboxylesterase (CES1A1 and CES1A2) genes
Bellott_2008_Cancer.Chemother.Pharmacol_61_481 Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene
Birkus_2008_Mol.Pharmacol_74_92 Activation of 9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases
Knight_2008_Hum.Mol.Genet_17_3847 A duplication at chromosome 11q12.2-11q12.3 is associated with spinocerebellar ataxia type 20
Ahn_2008_Bioorg.Med.Chem.Lett_18_6525 Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors
Edmondson_2008_Bioorg.Med.Chem.Lett_18_2409 Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors
Jun_2008_Eur.J.Med.Chem_43_1889 Synthesis and biological evaluation of pyrazoline analogues with beta-amino acyl group as dipeptidyl peptidase IV inhibitors
Liang_2008_Bioorg.Med.Chem.Lett_18_3706 Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design
Metzler_2008_Protein.Sci_17_240 Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation
Wallace_2008_Bioorg.Med.Chem.Lett_18_2362 Structure-based design and synthesis of benzimidazole derivatives as dipeptidyl peptidase IV inhibitors
Morisseau_2008_Chem.Res.Toxicol_21_951 Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase
Motoki_2008_Am.J.Physiol.Heart.Circ.Physiol_295_H2128 Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo
Dephoure_2008_Proc.Natl.Acad.Sci.U.S.A_105_10762 A quantitative atlas of mitotic phosphorylation
Keller_2008_J.Biomol.Screen_13_468 A high-throughput screen for endothelial lipase using HDL as substrate
Aoki_2008_Biochim.Biophys.Acta_1781_513 Two pathways for lysophosphatidic acid production
Nikonova_2008_Faseb.J_22_3925 Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance
Muccioli_2008_Chembiochem_9_2704 CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay
Okazaki_2008_J.Biol.Chem_283_33357 Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages
Casida_2008_Chem.Biol.Interact_175_355 Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids
Nomura_2008_Toxicol.Appl.Pharmacol_228_42 Dual roles of brain serine hydrolase KIAA1363 in ether lipid metabolism and organophosphate detoxification
Suckow_2008_Endocrinology_149_6006 Expression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretion
Yan_2008_Psychiatr.Genet_18_204 Analysis of the neuroligin 4Y gene in patients with autism
Samanta_2008_J.Biol.Chem_283_31617 Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis
Wilensky_2008_Nat.Med_14_1059 Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
Eydoux_2008_Biochemistry_47_9553 Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation
Xing_2008_Cell_133_154 Structural mechanism of demethylation and inactivation of protein phosphatase 2A
Longin_2008_Exp.Cell.Res_314_68 Spatial control of protein phosphatase 2A (de)methylation
Mallela_2008_Biochem.Biophys.Res.Commun_374_635 The functional importance of the N-terminal region of human prolylcarboxypeptidase
Chabrol_2008_J.Med.Genet_45_314 Deletion of C2orf34, PREPL and SLC3A1 causes atypical hypotonia-cystinuria syndrome
Martens_2008_Curr.Mol.Med_8_544 Multi-system disorder syndromes associated with cystinuria type I
Haffner_2008_Bioorg.Med.Chem.Lett_18_4360 Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP)
Lee_2008_J.Clin.Invest_118_2950 The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone
Misiunas_2008_Biophys.Chem_134_144 Thermomyces lanuginosus lipase in the liquid-crystalline phases of aqueous phytantriol: X-ray diffraction and vibrational spectroscopic studies
Otzen_2008_Colloids.Surf.B.Biointerfaces_64_223 Differential adsorption of variants of the Thermomyces lanuginosus lipase on a hydrophobic surface suggests a role for local flexibility
Sonesson_2008_Colloids.Surf.B.Biointerfaces_61_208 Adsorption and activity of Thermomyces lanuginosus lipase on hydrophobic and hydrophilic surfaces measured with dual polarization interferometry (DPI) and confocal microscopy
Wang_2008_Bioresour.Technol_99_7232 Improvement of biodiesel production by lipozyme TL IM-catalyzed methanolysis using response surface methodology and acyl migration enhancer
Fouts_2008_PLoS.Genet_4_e1000141 Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice
Lin_2008_J.Bacteriol_190_515 Characterization of integrative and conjugative element ICEKp1-associated genomic heterogeneity in a Klebsiella pneumoniae strain isolated from a primary liver abscess
Takarada_2008_J.Bacteriol_190_4139 Complete genome sequence of the soil actinomycete Kocuria rhizophila
Martin_2008_Nature_452_88 The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis
Morita_2008_DNA.Res_15_151 Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production
Callanan_2008_J.Bacteriol_190_727 Genome sequence of Lactobacillus helveticus, an organism distinguished by selective gene loss and insertion sequence element expansion
Siezen_2008_Appl.Environ.Microbiol_74_424 Genome-scale genotype-phenotype matching of two Lactococcus lactis isolates from plants identifies mechanisms of adaptation to the plant niche
Iwamoto_2008_Syst.Appl.Microbiol_31_269 Identification and cloning of a gene encoding tannase (tannin acylhydrolase) from Lactobacillus plantarum ATCC 14917(T)
Picardeau_2008_PLoS.ONE_3_E1607 Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis
Kim_2008_J.Bacteriol_190_3093 Complete genome sequence of Leuconostoc citreum KM20
Yang_2008_Pestic.Biochem.Physiol_91_32 Increased activity and reduced sensitivity of acetylcholinesterase associated with malathion resistance in a field population of the oriental migratory locust, Locusta migratoria manilensis (Meyen)
Mukherjee_2008_Biochemistry_47_6233 PLP catabolism: identification of the 2-(Acetamidomethylene)succinate hydrolase gene in Mesorhizobium loti MAFF303099
Yuan_2008_J.Nutr.Sci.Vitaminol.(Tokyo)_54_185 Gene identification and characterization of the pyridoxine degradative enzyme alpha-(N-acetylaminomethylene)succinic acid amidohydrolase from Mesorhizobium loti MAFF303099
Hou_2008_Biol.Direct_3_26 Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia
Auernik_2008_Appl.Environ.Microbiol_74_682 The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism
Fang_2008_J.Bacteriol_190_6014 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics
Dick_2008_Appl.Environ.Microbiol_74_2646 Genomic insights into Mn(II) oxidation by the marine alphaproteobacterium Aurantimonas sp. strain SI85-9A1
King_2008_Nature_451_783 The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
Holmes_2008_BMC.Evol.Biol_8_54 Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor
Du_2008_J.Lipid.Res_49_1646 Wolman disease\/cholesteryl ester storage disease: efficacy of plant-produced human lysosomal acid lipase in mice
Chen_2008_Nat.Struct.Mol.Biol_15_50 Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions
Koehnke_2008_Proc.Natl.Acad.Sci.U.S.A_105_1873 Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2
Chadman_2008_Autism.Res_1_147 Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice
Bolliger_2008_Proc.Natl.Acad.Sci.U.S.A_105_6421 Unusually rapid evolution of Neuroligin-4 in mice
Jamain_2008_Proc.Natl.Acad.Sci.U.S.A_105_1710 Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism
Miller_2008_J.Nutr_138_927 Carboxyl ester lipase from either mother's milk or the pancreas is required for efficient dietary triglyceride digestion in suckling mice
Hermo_2008_Mol.Reprod.Dev_75_565 Alterations in the testis of hormone sensitive lipase-deficient mice is associated with decreased sperm counts, sperm motility, and fertility
Galvin_2008_Pediatr.Dev.Pathol_11_185 A murine model of infantile neuronal ceroid lipofuscinosis-ultrastructural evaluation of storage in the central nervous system and viscera
Kim_2008_J.Clin.Invest_118_3075 Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice
Lyly_2008_Hum.Mol.Genet_17_1406 Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism
Saha_2008_FEBS.Lett_582_3823 RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis
Matsunaga_2008_J.Biol.Chem_283_28835 Mycolyltransferase-mediated glycolipid exchange in Mycobacteria
Stinear_2008_Genome.Res_18_729 Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis
Turenne_2008_J.Bacteriol_190_2479 Mycobacterium avium subsp. paratuberculosis and M. avium subsp. avium are independently evolved pathogenic clones of a much broader group of M. avium organisms
Schwelm_2008_Mycol.Res_112_138 Early expression of aflatoxin-like dothistromin genes in the forest pathogen Dothistroma septosporum
Raman_2008_BMC.Syst.Biol_2_109 targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis
West_2008_Vaccine_26_3853 Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis
Biswal_2008_J.Mol.Biol_381_897 The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor
Mazumdar_2008_Biochim.Biophys.Acta_1784_351 X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579
Shiloh_2008_Cell.Host.Microbe_3_323 Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection
Kumar_2008_J.Biol.Chem_283_18032 Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon
Mishra_2008_Infect.Immun_76_127 Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY
Lack_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_2 Structure of HsaD, a steroid-degrading hydrolase, from Mycobacterium tuberculosis
Rengarajan_2008_Proc.Natl.Acad.Sci.U.S.A_105_264 Mycobacterium tuberculosis Rv2224c modulates innate immune responses
Chung_2008_J.Bacteriol_190_6035 Complete genome sequence of Neisseria gonorrhoeae NCCP11945
Schoen_2008_Proc.Natl.Acad.Sci.U.S.A_105_3473 Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis
Peng_2008_Genomics_91_78 Characterization of ST-4821 complex, a unique Neisseria meningitidis clone
Wijekoon_2008_Funct.Plant.Biol_35_1112 The involvement of two epoxide hydrolase genes, NbEH1.1 and NbEH1.2, of Nicotiana benthamiana in the interaction with Colletotrichum destructivum, Colletotrichum orbiculare or Pseudomonas syringae pv. tabaci.
Liu_2008_J.Insect.Physiol_54_1495 Molecular cloning and characterization of a juvenile hormone esterase gene from brown planthopper, Nilaparvata lugens
Paul_2008_J.Bacteriol_190_5531 Genome sequence of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5T
Nakayama_2008_DNA.Res_15_185 The Whole-genome sequencing of the obligate intracellular bacterium Orientia tsutsugamushi revealed massive gene amplification during reductive genome evolution
Warren_2008_Nature_453_175 Genome analysis of the platypus reveals unique signatures of evolution
Shimada_2008_Nature_456_520 Structural basis for gibberellin recognition by its receptor GID1
Tanaka_2008_Nucleic.Acids.Res_36_D1028 The Rice Annotation Project Database (RAP-DB): 2008 update
Grisvard_2008_Eur.J.Protistol_44_278 Differentially expressed genes during the encystment-excystment cycle of the ciliate Sterkiella histriomuscorum
Nowack_2008_Curr.Biol_18_410 Chromatophore genome sequence of Paulinella sheds light on acquisition of photosynthesis by eukaryotes
Kosaka_2008_Genome.Res_18_442 The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota
van den Berg_2008_Nat.Biotechnol_26_1161 Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum
Colombres_2008_J.Comput.Aided.Mol.Des_22_19 An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum
Bowler_2008_Nature_456_239 The Phaeodactylum genome reveals the evolutionary history of diatom genomes
Luo_2008_BMC.Genomics_9_386 Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562
Waterfield_2008_Proc.Natl.Acad.Sci.U.S.A_105_15967 Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts
Urbanczyk_2008_J.Bacteriol_190_3494 Phylogenetic analysis of the incidence of lux gene horizontal transfer in Vibrionaceae
Kube_2008_BMC.Genomics_9_306 The linear chromosome of the plant-pathogenic mycoplasma 'Candidatus Phytoplasma mali'
Rensing_2008_Science_319_64 The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants
Ralph_2008_BMC.Genomics_9_484 A conifer genomics resource of 200,000 spruce (Picea spp.) ESTs and 6,464 high-quality, sequence-finished full-length cDNAs for Sitka spruce (Picea sitchensis)
Palme_2008_Mol.Biol.Evol_25_2567 Patterns of divergence among conifer ESTs and polymorphism in Pinus sylvestris identify putative selective sweeps
Christiansen_2008_Mol.Biol.Evol_25_1695 Nontoxic strains of cyanobacteria are the result of major gene deletion events induced by a transposable element
Pain_2008_Nature_455_799 The genome of the simian and human malaria parasite Plasmodium knowlesi
Carlton_2008_Nature_455_757 Comparative genomics of the neglected human malaria parasite Plasmodium vivax
Espagne_2008_Genome.Biol_9_R77 The genome sequence of the model ascomycete fungus Podospora anserina
Ishida_2008_Proc.Natl.Acad.Sci.U.S.A_105_9076 Chiral discrimination of the Japanese beetle sex pheromone and a behavioral antagonist by a pheromone-degrading enzyme
Ralph_2008_BMC.Genomics_9_57 Analysis of 4,664 high-quality sequence-finished poplar full-length cDNA clones and their utility for the discovery of genes responding to insect feeding
Naito_2008_DNA.Res_15_215 Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis
Xu_2008_J.Mol.Biol_375_708 Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism
Dieterich_2008_Nat.Genet_40_1193 The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism
Dherbecourt_2008_Microb.Cell.Fact_7_16 A genomic search approach to identify esterases in Propionibacterium freudenreichii involved in the formation of flavour in Emmental cheese
Pearson_2008_J.Bacteriol_190_4027 Complete genome sequence of uropathogenic Proteus mirabilis, a master of both adherence and motility
Mathee_2008_Proc.Natl.Acad.Sci.U.S.A_105_3100 Dynamics of Pseudomonas aeruginosa genome evolution
Hausmann_2008_FEMS.Microbiol.Lett_282_65 Mutations towards enantioselectivity adversely affect secretion of Pseudomonas aeruginosa lipase
Qiu_2008_Microbiology_154_2119 ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa
Ye_2008_Am.J.Physiol.Cell.Physiol_295_C807 Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif
MacEachran_2008_Infect.Immun_76_3197 Cif is negatively regulated by the TetR family repressor CifR
Zhu_2008_J.Bacteriol_190_3147 RhlA converts beta-hydroxyacyl-acyl carrier protein intermediates in fatty acid synthesis to the beta-hydroxydecanoyl-beta-hydroxydecanoate component of rhamnolipids in Pseudomonas aeruginosa
Kumar_2008_World.J.Microbiol.Biotechnol_24_1047 Biosurfactant production and hydrocarbon-degradation by halotolerant and thermotolerant Pseudomonas sp.
Hidalgo_2008_Protein.Eng.Des.Sel_21_567 A one-pot, simple methodology for cassette randomisation and recombination for focused directed evolution
Papageorgiou_2008_J.Mol.Biol_382_1184 Structural basis of poly(3-hydroxybutyrate) hydrolysis by PhaZ7 depolymerase from Paucimonas lemoignei
Fuchu_2008_Appl.Microbiol.Biotechnol_79_627 Insertion sequence-based cassette PCR: cultivation-independent isolation of gamma-hexachlorocyclohexane-degrading genes from soil DNA
Jimenez_2008_Proc.Natl.Acad.Sci.U.S.A_105_11329 Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440
Kuwahara_2008_Protein.Eng.Des.Sel_21_737 Importance of the Ca2+-binding sites in the N-catalytic domain of a family I.3 lipase for activity and stability
Suzuki_2008_Photochem.Photobiol.Sci_7_1260 Expression and purification of pheophorbidase, an enzyme catalyzing the formation of pyropheophorbide during chlorophyll degradation: comparison with the native enzyme
Woo_2008_Protein.Sci_17_725 Structure-function studies on the active site of the coelenterazine-dependent luciferase from Renilla
Wiens_2008_J.Bacteriol_190_6970 Genome sequence of the fish pathogen Renibacterium salmoninarum suggests reductive evolution away from an environmental Arthrobacter ancestor
Hama_2008_Appl.Microbiol.Biotechnol_79_1009 Role of N-terminal 28-amino-acid region of Rhizopus oryzae lipase in directing proteins to secretory pathway of Aspergillus oryzae
Yoo_2008_Biotechnol.Lett_30_1807 Enantioselective resolution of racemic styrene oxide at high concentration using recombinant Pichia pastoris expressing epoxide hydrolase of Rhodotorula glutinis in the presence of surfactant and glycerol
Stsiapanava_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_137 Crystals of DhaA mutants from Rhodococcus rhodochrous NCIMB 13064 diffracted to ultrahigh resolution: crystallization and preliminary diffraction analysis
Ellison_2008_Infect.Immun_76_542 Genomic comparison of virulent Rickettsia rickettsii Sheila Smith and avirulent Rickettsia rickettsii Iowa
Weiner_2008_PLoS.Genet_4_E1000087 Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T
Thomson_2008_Genome.Res_18_1624 Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287\/91 provides insights into evolutionary and host adaptation pathways
Wilson-Grady_2008_J.Proteome.Res_7_1088 Phosphoproteome analysis of fission yeast
Castelli_2008_J.Bacteriol_190_213 Enterobacterial common antigen integrity is a checkpoint for flagellar biogenesis in Serratia marcescens
Suzuki_2008_FEMS.Microbiol.Lett_285_16 An outer membrane autotransporter, AoaA, of Azorhizobium caulinodans is required for sustaining high N2-fixing activity of stem nodules
Lampidonis_2008_Gene_416_30 Cloning and functional characterization of the ovine Hormone Sensitive Lipase (HSL) full-length cDNAs: an integrated approach
Wang_2008_PLoS.ONE_3_E1937 Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3
Thomaeus_2008_Protein.Sci_17_1275 Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability
Nagy_2008_Genome.Res_18_1918 Pathogen corruption and site-directed recombination at a plant disease resistance gene cluster
Manickam_2008_J.Appl.Microbiol_104_952 Isolation of hexachlorocyclohexane-degrading Sphingomonas sp. by dehalogenase assay and characterization of genes involved in gamma-HCH degradation
Neoh_2008_Antimicrob.Agents.Chemother_52_45 Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance
Baba_2008_J.Bacteriol_190_300 Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes: polymorphism and evolution of two major pathogenicity islands
Frikha_2008_FEMS.Microbiol.Lett_286_207 3-D structure modelling of the Staphylococcus simulans lipase: conformational changes, substrate specificity and novel structural features
Sivaraman_2008_BMC.Genomics_9_433 Genome sequencing and analysis reveals possible determinants of Staphylococcus aureus nasal carriage
Beres_2008_PLoS.ONE_3_E3026 Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: new information about an old disease
Ohnishi_2008_J.Bacteriol_190_4050 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350
Crossman_2008_Genome.Biol_9_R74 The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants
Kim_2008_Proteins_70_578 The crystal structure of the estA protein, a virulence factor from Streptococcus pneumoniae
Harris_2008_DNA.Cell.Biol_27_467 Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence
McShan_2008_J.Bacteriol_190_7773 Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes
Achard_2008_Antimicrob.Agents.Chemother_52_2767 Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene
Eys_2008_Antimicrob.Agents.Chemother_52_1686 Three thioesterases are involved in the biosynthesis of phosphinothricin tripeptide in Streptomyces viridochromogenes Tu494
Park_2008_J.Bacteriol_190_8086 A novel thermostable arylesterase from the archaeon Sulfolobus solfataricus P1: purification, characterization, and expression
Sievert_2008_Appl.Environ.Microbiol_74_1145 Genome of the epsilonproteobacterial chemolithoautotroph Sulfurimonas denitrificans
Hermann_2008_J.Biotechnol_133_301 Alternative pig liver esterase (APLE) - cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst
Oboh_2008_J.Biochem.Mol.Toxicol_22_51 Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase
Djeridane_2008_Chem.Biol.Interact_172_22 Inhibition of porcine liver carboxylesterase by a new flavone glucoside isolated from Deverra scoparia
Kanai_2008_J.Med.Chem_51_7514 Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules
Maier_2008_Science_321_1315 The crystal structure of a mammalian fatty acid synthase
Chen_2008_J.Biol.Chem_283_25854 Identification and characterization of bacterial cutinase
Taji_2008_BMC.Plant.Biol_8_115 Large-scale collection and annotation of full-length enriched cDNAs from a model halophyte, Thellungiella halophila
Lee_2008_J.Bacteriol_190_7491 The complete genome sequence of Thermococcus onnurineus NA1 reveals a mixed heterotrophic and carboxydotrophic metabolism
Anderson_2008_J.Bacteriol_190_2957 Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction
Okai_2008_Proteins_70_1646 Crystal structure of the proline iminopeptidase-related protein TTHA1809 from Thermus thermophilus HB8
Harel_2008_J.Am.Chem.Soc_130_7856 Crystal structure of thioflavin T bound to the peripheral site of Torpedo californica acetylcholinesterase reveals how thioflavin T acts as a sensitive fluorescent reporter of ligand binding to the acylation site
Colletier_2008_Proc.Natl.Acad.Sci.U.S.A_105_11742 Shoot-and-Trap: use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography
Matejkova_2008_BMC.Microbiol_8_76 Complete genome sequence of Treponema pallidum ssp. pallidum strain SS14 determined with oligonucleotide arrays
Srivastava_2008_Nature_454_955 The Trichoplax genome and the nature of placozoans
Richards_2008_Nature_452_949 The genome of the model beetle and pest Tribolium castaneum
Zaugg_2008_Int.J.Med.Microbiol_298_669 Trichophyton rubrum secreted and membrane-associated carboxypeptidases
Merritt_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_474 Structure of a Trypanosoma brucei alpha\/beta-hydrolase fold protein with unknown function
Yang_2008_Toxicon_51_289 A phospholipase A1 platelet activator from the wasp venom of Vespa magnifica (Smith)
Naka_2008_Environ.Microbiol_10_265 Reactivation of the vanchrobactin siderophore system of Vibrio anguillarum by removal of a chromosomal insertion sequence originated in plasmid pJM1 encoding the anguibactin siderophore system
Feng_2008_PLoS.ONE_3_E4053 A recalibrated molecular clock and independent origins for the cholera pandemic clones
O'Grady_2008_Appl.Environ.Microbiol_74_61 Mutations in the lux operon of natural dark mutants in the genus Vibrio
Vorholter_2008_J.Biotechnol_134_33 The genome of Xanthomonas campestris pv. campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis
Salzberg_2008_BMC.Genomics_9_204 Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99A
Nakajima_2008_J.Bacteriol_190_7819 Dipeptidyl aminopeptidase IV from Stenotrophomonas maltophilia exhibits activity against a substrate containing a 4-hydroxyproline residue
Borneman_2008_FEMS.Yeast.Res_8_1185 Comparative genome analysis of a Saccharomyces cerevisiae wine strain
Wogulis_2008_Biochemistry_47_1608 Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence
Albuquerque_2008_Mol.Cell.Proteomics_7_1389 A multidimensional chromatography technology for in-depth phosphoproteome analysis
Legler_2008_Biochemistry_47_9592 Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase
Sinha_2008_Genetics_180_1661 Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast
Thoms_2008_Febs.J_275_504 Lpx1p is a peroxisomal lipase required for normal peroxisome morphology
Rocha_2008_Mol.Plant.Pathol_9_293 Ctf1, a transcriptional activator of cutinase and lipase genes in Fusarium oxysporum is dispensable for virulence
Pope_2008_FEMS.Microbiol.Ecol_64_9 Metagenomic analysis of a freshwater toxic cyanobacteria bloom
Dybvig_2008_Infect.Immun_76_4000 Genome of Mycoplasma arthritidis
Hjerde_2008_BMC.Genomics_9_616 The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay
Siboo_2008_J.Bacteriol_190_6188 Characterization of the accessory Sec system of Staphylococcus aureus
Yi_2008_Tetrahedron_64_8947 FRET-based fluorescence probes for hydrolysis study and pig liver esterase activity
Mattes_2008_Appl.Environ.Microbiol_74_6405 The genome of Polaromonas sp. strain JS666: insights into the evolution of a hydrocarbon- and xenobiotic-degrading bacterium, and features of relevance to biotechnology
Kim_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_151_52 Pancreatic lipase-related protein (PY-PLRP) highly expressed in the vitellogenic ovary of the scallop, Patinopecten yessoensis
Okada_2008_Gen.Comp.Endocrinol_155_623 Differential display analysis of gene expression in female-to-male sex-reversing gonads of the frog Rana rugosa
Jose_2008_Comp.Biochem.Physiol.A.Mol.Integr.Physiol_150_347 Lipoprotein lipase (LPL) is highly expressed and active in the ovary of European sea bass (Dicentrarchus labrax L.), during gonadal development
McDermott_2008_PLoS.ONE_3_E2442 Estimation of isolation times of the island species in the Drosophila simulans complex from multilocus DNA sequence data
Llopart_2008_J.Mol.Evol_66_224 A new test for selection applied to codon usage in Drosophila simulans and D. mauritiana
Freeman_2008_Biological.Bulletin_214_284 cDNA sequences for transcription factors and signaling proteins of the hemichordate Saccoglossus kowalevskii: efficacy of the expressed sequence tag (EST) approach for evolutionary and developmental studies of a new organism
Bercovich_2008_Int.J.Syst.Evol.Microbiol_58_2363 Bizionia argentinensis sp. nov., isolated from surface marine water in Antarctica
Weber_2008_Chem.Biol_15_175 Molecular analysis of the kirromycin biosynthetic gene cluster revealed beta-alanine as precursor of the pyridone moiety
Lazarus_2008_Inflamm.Res_57_18 An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis
Li_2008_J.Bacteriol_190_251 Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner
Chen_2008_J.Agric.Food.Chem_56_11767 Exploring the distribution of citrinin biosynthesis related genes among Monascus species
Sakai_2008_J.Biosci.Bioeng_106_466 Construction of a citrinin gene cluster expression system in heterologous Aspergillus oryzae
Miyamoto_2008_Mol.Plant.Microbe.Interact_21_1591 Functional analysis of a multicopy host-selective ACT-toxin biosynthesis gene in the tangerine pathotype of Alternaria alternata using RNA silencing
Son_2008_J.Appl.Microbiol_104_692 Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans
Reeves_2008_Appl.Environ.Microbiol_74_5121 Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia
Chen_2008_J.Agric.Food.Chem_56_5639 Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus
Chung_2008_Microbiol.(Reading)_154_3556 Determination of a transcriptional regulator-like gene involved in biosynthesis of elsinochrome phytotoxin by the citrus scab fungus, Elsino fawcettii
Liao_2008_Mol.Plant.Microbe.Interact_21_469 Genetic dissection defines the roles of elsinochrome Phytotoxin for fungal pathogenesis and conidiation of the citrus pathogen Elsino fawcettii
Atoui_2008_Appl.Environ.Microbiol_74_3596 Aspergillus nidulans natural product biosynthesis is regulated by mpkB, a putative pheromone response mitogen-activated protein kinase
Schneider_2008_Fungal.Genet.Biol_45_302 The Aspergillus nidulans enzyme TdiB catalyzes prenyltransfer to the precursor of bioactive asterriquinones
Wang_2008_Chem.Biol_15_1328 Functional characterization of the biosynthesis of radicicol, an Hsp90 inhibitor resorcylic acid lactone from Chaetomium chiversii
Schneider_2008_Fungal.Genet.Biol_45_1487 Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides
Parmo-Folloni_2008_Chem.Biol.Interact_175_135 Two new mutations of the human BCHE gene (IVS3-14T>C and L574fsX576)
Mikami_2008_Pharmacogenet.Genomics_18_213 Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population
Perrin_2008_Invert.Neurosci_8_147 Thermal denaturation of wild type and mutant recombinant acetylcholinesterase from amphioxus: effects of the temperature of in vitro expression and of reversible inhibitors
Criniti_2008_Pestic.Biochem.Physiol_90_168 Biochemical and molecular diagnosis of insecticide resistance conferred by esterase, MACE, kdr and super-kdr based mechanisms in Italian strains of the peach potato aphid, Myzus persicae (Sulzer)
Nachon_2008_Febs.J_275_2659 Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel
Zheng_2008_J.Am.Chem.Soc_130_12148 Most efficient cocaine hydrolase designed by virtual screening of transition states
Brimijoin_2008_Neuropsychopharmacology_33_2715 A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats
Alout_2008_Chem.Biol.Interact_175_138 Amino-acid substitutions in acetylcholinesterase 1 involved in insecticide resistance in mosquitoes
Djogbenou_2008_PLoS.One_3_e2172 Evidence of introgression of the ace-1(R) mutation and of the ace-1 duplication in West African Anopheles gambiae s. s
Kakani_2008_Insect.Biochem.Mol.Biol_38_781 A small deletion in the olive fly acetylcholinesterase gene associated with high levels of organophosphate resistance
Hsu_2008_Insect.Biochem.Mol.Biol_38_146 Alterations of the acetylcholinesterase enzyme in the oriental fruit fly Bactrocera dorsalis are correlated with resistance to the organophosphate insecticide fenitrothion
Furtado-Alle_2008_Chem.Biol.Interact_175_115 Association of variants of the -116 site of the butyrylcholinesterase BCHE gene to enzyme activity and body mass index
Morini_2008_Bioorg.Med.Chem_16_9911 Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity
Lim_2008_Yonsei.Med.J_49_472 Effect of itopride hydrochloride on the ileal and colonic motility in guinea pig in vitro
Vafiadi_2008_J.Biotechnol_133_497 Enzymatic synthesis of butyl hydroxycinnamates and their inhibitory effects on LDL-oxidation
Chung_2008_J.Hepatol_48_471 Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL)
Alves_2008_Pestic.Biochem.Physiol_90_26 Effects of the synergist S,S,S-tributyl phosphorotrithioate on indoxacarb toxicity and metabolism in the European corn borer, Ostrinia nubilalis (Hubner)
Ahmad_2008_Pestic.Biochem.Physiol_91_24 Potentiation between pyrethroid and organophosphate insecticides in resistant field populations of cotton bollworm Helicoverpa armigera (Lepidoptera: Noctuidae) in Pakistan
Ren_2008_J.Agric.Food.Chem_56_2388 pH memory of immobilized lipase for (+\/-)-menthol resolution in ionic liquid
Fehling_2008_Biotechnol.Bioeng_99_1074 Linear copolymeric poly(thia-alkanedioates) by lipase-catalyzed esterification and transesterification of 3,3'-thiodipropionic acid and its dimethyl ester with alpha,omega-alkanediols
Nakamura_2008_Drug.Metab.Lett_2_280 Decreased valproate level caused by VPA-glucuronidase inhibition by carbapenem antibiotics
Chiou_2008_Appl.Biochem.Biotechnol_150_337 Activation mechanisms of butyrylcholinesterase by 2,4,6-trinitrotoluene, 3,3-dimethylbutyl-N-n-butylcarbamate, and 2-trimethylsilyl-ethyl-N-n-butylcarbamate
Van Goethem_2008_Bioorg.Med.Chem.Lett_18_4159 Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors
Van der Veken_2008_Bioorg.Med.Chem.Lett_18_4154 Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads
Chatterjee_2008_Microbiol.(Reading)_154_3338 Metabolic cooperation of Gordonia sp. strain MTCC 4818 and Arthrobacter sp. strain WY in the utilization of butyl benzyl phthalate: effect of a novel co-culture in the degradation of a mixture of phthalates
Pereira_2008_Biochem.Pharmacol_75_1827 Effects of estrogen on intracellular signaling pathways linked to activation of muscarinic acetylcholine receptors and on acetylcholinesterase activity in rat hippocampus
Darvesh_2008_J.Med.Chem_51_4200 Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase
Scipione_2008_Bioorg.Med.Chem.Lett_18_309 4-Aminopyridine derivatives with anticholinesterase and antiamnesic activity
Donati_2008_Expert.Opin.Pharmacother_9_1375 Sugammadex: a cyclodextrin to reverse neuromuscular blockade in anaesthesia
Eikermann_2008_Br.J.Anaesth_101_344 Neostigmine but not sugammadex impairs upper airway dilator muscle activity and breathing
Jones_2008_Anesthesiology_109_816 Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine
Schara_2008_Neurotherapeutics_5_542 Therapeutic strategies in congenital myasthenic syndromes
Miller_2008_J.Med.Entomol_45_905 Differential response to diazinon and coumaphos in a strain of Boophilus microplus (Acari: Ixodidae) collected in Mexico
Lopez-Raez_2008_New.Phytol_178_863 Tomato strigolactones are derived from carotenoids and their biosynthesis is promoted by phosphate starvation
Yoneyama_2008_New.Phytol_179_484 Strigolactones, host recognition signals for root parasitic plants and arbuscular mycorrhizal fungi, from Fabaceae plants
Takahashi_2008_J.Pharm.Sci_97_5434 Allosteric kinetics of human carboxylesterase 1: species differences and interindividual variability
Zhaoxu_2008_Pharmazie_63_156 Rifabutin autoinduction is caused by involvement of cytochrome P450 and cholinesterase
Van der Meulen_2008_Biomacromolecules_9_3404 Polymers from functional macrolactones as potential biomaterials: enzymatic ring opening polymerization, biodegradation, and biocompatibility
Virta_2008_J.Nucl.Med_49_347 1-11C-methyl-4-piperidinyl-N-butyrate radiation dosimetry in humans by dynamic organ-specific evaluation
da Silva-Lopez_2008_Acta.Trop_107_159 Purification and subcellular localization of a secreted 75 kDa Trypanosoma cruzi serine oligopeptidase
Caboni_2008_J.Agric.Food.Chem_56_7696 Liquid chromatography-tandem mass spectrometric ion-switching determination of chlorantraniliprole and flubendiamide in fruits and vegetables
Williams_2008_Drug.Metab.Dispos_36_1227 The biotransformation of prasugrel, a new thienopyridine prodrug, by the human carboxylesterases 1 and 2
Mori_2008_Bioorg.Med.Chem.Lett_18_4249 Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: effect of alkyl chain length
Briggs_2008_Br.J.Pharmacol_153_1054 alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues
Guindon_2008_Br.J.Pharmacol_153_1341 A physiological role for endocannabinoid-derived products of cyclooxygenase-2-mediated oxidative metabolism
Jiang_2008_Chem.Pharm.Bull.(Tokyo)_56_1286 Derivatives of vibralactone from cultures of the basidiomycete Boreostereum vibrans
Rivera-Becerril_2008_J.Med.Chem_51_5271 Synthesis and biological evaluation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitors
Meikle_2008_Biochem.J_411_71 Effect of lysosomal storage on bis(monoacylglycero)phosphate
Dubern_2008_Mol.Biosyst_4_882 Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species
Nave_2008_J.Asthma.Allergy_1_11 Metabolism of ciclesonide in the upper and lower airways: review of available data
Rimmerman_2008_Br.J.Pharmacol_153_380 Compartmentalization of endocannabinoids into lipid rafts in a dorsal root ganglion cell line
Ortar_2008_J.Med.Chem_51_6970 Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism
Kim_2008_Biotechnol.Lett_30_329 A novel biotransformation of 2-formyl-6-naphthoic acid to 2,6-naphthalene dicarboxylic acid by Pseudomonas sp. for the purification of crude 2,6-naphthalene dicarboxylic acid
Ong_2008_J.Sep.Sci_31_2476 Enantioseparation of (R,S)-ketoprofen using Candida antarctica lipase B in an enzymatic membrane reactor
Kim_2008_Biotechnol.Lett_30_127 Biosynthesis of (R)-phenyl-1,2-ethanediol from racemic styrene oxide by using bacterial and marine fish epoxide hydrolases
Xie_2008_J.Med.Chem_51_2027 Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation
Lim_2008_Clin.Ther_30_1817 Pharmacokinetics, pharmacodynamics, and tolerability of the dipeptidyl peptidase IV inhibitor LC15-0444 in healthy Korean men: a dose-block-randomized, double-blind, placebo-controlled, ascending single-dose, Phase I study
Fife_2008_J.Pharmacol.Exp.Ther_327_707 Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation
Dandavate_2008_J.Microbiol.Biotechnol_18_735 Reusability of surfactant-coated Candida rugosa lipase immobilized in gelatin microemulsion-based organogels for ethyl isovalerate synthesis
Castro_2008_Eur.J.Pharmacol_580_339 CNS-selective noncompetitive cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline
Garcia-Palomero_2008_Neurodegener.Dis_5_153 Potent beta-amyloid modulators
Rosini_2008_J.Med.Chem_51_4381 Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush
Monti_2008_J.Biotechnol_133_65 Purification and characterization of the enantioselective esterase from Kluyveromyces marxianus CBS 1553
Connolly_2008_J.Med.Chem_51_6005 Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety
Badiou_2008_Chem.Biol.Interact_175_406 Is acetylcholinesterase a pertinent biomarker to detect exposure of pyrethroids? A study case with deltamethrin
Badiou_2008_Ecotoxicol.Environ.Saf_69_246 Honeybee Apis mellifera acetylcholinesterase--a biomarker to detect deltamethrin exposure
Jackson_2008_J.Mol.Biol_375_1189 In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase
Wu_2008_Planta_227_1161 Methyl jasmonate-elicited herbivore resistance: does MeJA function as a signal without being hydrolyzed to JA?
Wheelock_2008_Bioorg.Med.Chem_16_2114 Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH)
Umehara_2008_Nature_455_195 Inhibition of shoot branching by new terpenoid plant hormones
Gomez-Roldan_2008_Nature_455_189 Strigolactone inhibition of shoot branching
Stankovic_2008_Clin.Vaccine.Immunol_15_794 Distribution of dipeptidyl peptidase IV in patients with chronic tonsillitis
Bednarek_2008_Acta.Crystallogr.Sect.E.Struct.Rep.Online_64_o1277 N,N'-Bis(2-hydroxy-ethyl)benzene-1,4-dicarboxamide
Nimchua_2008_J.Ind.Microbiol.Biotechnol_35_843 Screening of tropical fungi producing polyethylene terephthalate-hydrolyzing enzyme for fabric modification
Brueckner_2008_J.Polym.Sci.Part.A:Polym.Chem_46_6425 Enzymatic and chemical hydrolysis of poly(ethylene terephthalate) fabrics
Wang_2008_Assay.Drug.Dev.Technol_6_387 A fluorescence-based assay for monoacylglycerol lipase compatible with inhibitor screening
Nallapaneni_2008_Neurotoxicol_29_1037 Pharmacological enhancement of endocannabinoid signaling reduces the cholinergic toxicity of diisopropylfluorophosphate
Duncan_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_295_G1255 Distribution and function of monoacylglycerol lipase in the gastrointestinal tract
Burston_2008_J.Pharmacol.Exp.Ther_327_546 N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase
Zvonok_2008_Chem.Biol_15_854 Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis
Yucel_2008_Arch.Biochem.Biophys_478_201 Comparative effects of cationic triarylmethane, phenoxazine and phenothiazine dyes on horse serum butyrylcholinesterase
Mohler_2008_J.Am.Coll.Cardiol_51_1632 The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study
Serruys_2008_Circulation_118_1172 Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque
Gallwitz_2008_IDrugs_11_906 Saxagliptin, a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
He_2008_J.Clin.Pharmacol_48_85 Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects
Lee_2008_Eur.J.Pharmacol_589_306 Pharmacokinetic, pharmacodynamic, and efficacy profiles of alogliptin, a novel inhibitor of dipeptidyl peptidase-4, in rats, dogs, and monkeys
Moritoh_2008_Eur.J.Pharmacol_588_325 Chronic administration of alogliptin, a novel, potent, and highly selective dipeptidyl peptidase-4 inhibitor, improves glycemic control and beta-cell function in obese diabetic ob\/ob mice
Christopher_2008_Clin.Ther_30_513 Pharmacokinetics, pharmacodynamics, and tolerability of single increasing doses of the dipeptidyl peptidase-4 inhibitor alogliptin in healthy male subjects
Covington_2008_Clin.Ther_30_499 Pharmacokinetic, pharmacodynamic, and tolerability profiles of the dipeptidyl peptidase-4 inhibitor alogliptin: a randomized, double-blind, placebo-controlled, multiple-dose study in adult patients with type 2 diabetes
Deacon_2008_Curr.Opin.Investig.Drugs_9_402 Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes
Green_2008_Vasc.Health.Risk.Manag_4_743 New combination treatments in the management of diabetes: focus on sitagliptin-metformin
Jackson_2008_Hypertension_51_1637 Sitagliptin augments sympathetic enhancement of the renovascular effects of angiotensin II in genetic hypertension
Gagliardino_2008_Expert.Opin.Pharmacother_9_1495 New treatments for type 2 diabetes mellitus: combined therapy with sitagliptin
Kim_2008_Diabetes_57_1331 Inhibition of dipeptidyl peptidase IV with sitagliptin (MK0431) prolongs islet graft survival in streptozotocin-induced diabetic mice
Mistry_2008_Br.J.Clin.Pharmacol_66_36 Sitagliptin, an dipeptidyl peptidase-4 inhibitor, does not alter the pharmacokinetics of the sulphonylurea, glyburide, in healthy subjects
Xu_2008_Diabetes.Obes.Metab_10_1212 Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on beta-cell function in patients with type 2 diabetes: a model-based approach
Mistry_2008_J.Clin.Pharmacol_48_592 Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood pressure in nondiabetic patients with mild to moderate hypertension
Matthes_2008_Dtsch.Med.Wochenschr_133_2233 [Sitagliptin. DPP-4 inhibitors as a useful extension of oral diabetes therapy?]
van Bronswijk_2008_Ned.Tijdschr.Geneeskd_152_876 [New drugs\; exenatide and sitagliptin]
Pham_2008_Am.J.Health.Syst.Pharm_65_521 Sitagliptin: a novel agent for the management of type 2 diabetes mellitus
Williams-Herman_2008_BMC.Endocr.Disord_8_14 Safety and tolerability of sitagliptin in patients with type 2 diabetes: a pooled analysis
Levasseur_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_862_140 Enantiospecific gas chromatographic-mass spectrometric analysis of urinary methylphenidate: implications for phenotyping
Makhaeva_2008_Dokl.Biochem.Biophys_423_352 Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols
Hoover_2008_Bioorg.Med.Chem.Lett_18_5838 Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling
Liu_2008_J.Cell.Physiol_216_91 L- and N-current but not M-current inhibition by M1 muscarinic receptors requires DAG lipase activity
Ono_2008_Biol.Pharm.Bull_31_638 Oseltamivir, an anti-influenza virus drug, produces hypothermia in mice
Zutter_2008_J.Org.Chem_73_4895 New, efficient synthesis of oseltamivir phosphate (Tamiflu) via enzymatic desymmetrization of a meso-1,3-cyclohexanedicarboxylic acid diester
Meyer-Losic_2008_Clin.Cancer.Res_14_2145 DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies
Anikienko_2008_Chem.Biol.Interact_175_286 Compounds with the dioxopyrimidine cycle inhibit cholinesterases from different groups of animals
Quitschau_2008_European.J.Org.Chem_2008_5117 The New Metabolite (S)-Cinnamoylphosphoramide from Streptomyces sp. and Its Total Synthesis
Lin_2008_J.Agric.Food.Chem_56_4273 Single and joint acute toxicity of isocarbophos enantiomers to Daphnia magna
Ding_2008_Chem.Res.Toxicol_21_1787 Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin
Grigoryan_2008_Chem.Biol.Interact_175_180 Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents
Ge_2008_Chemistry_14_376 Hopeahainol A: an acetylcholinesterase inhibitor from Hopea hainanensis
Kamal_2008_J.Neural.Transm.(Vienna)_115_889 Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis
Kamal_2008_Neurochem.Res_33_745 Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental Alzheimer therapeutic, dihydrobenzodioxepine cymserine
Radic_2008_Chem.Biol.Interact_175_161 Probing gorge dimensions of cholinesterases by freeze-frame click chemistry
Sultana_2008_J.Enzyme.Inhib.Med.Chem_23_739 Oleanolic acid and related derivatives as medicinally important compounds
Elersek_2008_Biofouling_24_137 Influence of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai on the growth of algae and wood decay fungi
Yan_2008_J.Econ.Entomol_101_1897 Dynamics of esterase alleles in Culex pipiens complex mosquitoes in Beijing
Liu_2008_Neuropharmacol_54_1086 Inhibition of NMDA-gated ion channels by bis(7)-tacrine: whole-cell and single-channel studies
Yu_2008_J.Pharm.Biomed.Anal_46_75 The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine
Zhang_2008_Biomed.Chromatogr_22_414 Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry
Rosenberry_2008_Biochemistry_47_13056 Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter
Rosenberry_2008_Chem.Biol.Interact_175_235 Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis
Bandyopadhyay_2008_J.Org.Chem_73_8386 Synthesis and biological evaluation of a phosphonate analog of the natural acetyl cholinesterase inhibitor cyclophostin
Siatka_2008_Ceska.Slov.Farm_57_17 Effects of auxins on growth and scopoletin accumulation in cell suspension cultures of Angelica archangelica L
Orhan_2008_Z.Naturforsch.C_63_366 Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity
Ruby_2008_Proc.Natl.Acad.Sci.U.S.A_105_14561 Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins
Nomura_2008_Nat.Chem.Biol_4_373 Activation of the endocannabinoid system by organophosphorus nerve agents
Giron-Perez_2008_Fish.Shellfish.Immunol_25_517 Effects of diazinon and diazoxon on the lymphoproliferation rate of splenocytes from Nile tilapia (Oreochromis niloticus): the immunosuppresive effect could involve an increase in acetylcholine levels
Mehrani_2008_Toxicol.In.Vitro_22_1257 Changes in mRNA and protein levels of nicotinic acetylcholine receptors in Diazoxon exposed pC12 cells
Bielza_2008_J.Econ.Entomol_101_1685 Impact of production system on development of insecticide resistance in Frankliniella occidentalis (Thysanoptera: Thripidae)
Zhao_2008_J.Pestic.Sci_33_371 Design of novel carbamate acetylcholinesterase inhibitors based on the multiple binding sites of acetylcholinesterase
Al-Rehiayani_2008_Pestic.Biochem.Physiol_90_19 Acetylcholinesterase in selected plant-parasitic nematodes: Inhibition, kinetic and comparative studies
Leoni_2008_Toxicol.Appl.Pharmacol_233_343 The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion
Berkov_2008_Phytochem.Anal_19_411 Rapid TLC\/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts
Valdes-Ramirez_2008_Anal.Bioanal.Chem_392_699 Acetylcholinesterase-based biosensors for quantification of carbofuran, carbaryl, methylparaoxon, and dichlorvos in 5\% acetonitrile
Carcoba_2008_Pharmacol.Biochem.Behav_88_374 In utero methanesulfonyl fluoride differentially affects learning and maze performance in the absence of long-lasting cholinergic changes in the adult rat
Li_2008_J.Environ.Sci.Health.B_43_638 Toxic effects of chlorpromazine on Carassius auratus and its oxidative stress
Suzuki_2008_Intern.Med_47_983 Nocturnal hypersalivation caused by distigmine bromide in a patient with multiple system atrophy
Onodera_2008_Chudoku.Kenkyu_21_161 [Acute poisoning due to distigmine bromide]
Bharucha_2008_Clin.Auton.Res_18_194 Pilot study of pyridostigmine in constipated patients with autonomic neuropathy
Nobrega_2008_Int.J.Cardiol_125_418 Cholinergic stimulation with pyridostigmine prevents the impairment in ventricular function during mental stress in coronary artery disease patients
Langkilde_2008_J.Agric.Food.Chem_56_8753 Acute toxicity of high doses of the glycoalkaloids, alpha-solanine and alpha-chaconine, in the Syrian Golden hamster
Petroianu_2008_Pharmazie_63_325 The history of cholinesterase inhibitors: who was Moschnin(e)?
Padwal_2008_Curr.Opin.Investig.Drugs_9_414 Cetilistat, a new lipase inhibitor for the treatment of obesity
Yamada_2008_Horm.Metab.Res_40_539 Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats
Krstic_2008_J.Enzyme.Inhib.Med.Chem_23_562 Inhibition of AChE by malathion and some structurally similar compounds
Khot_2008_Pest.Manag.Sci_64_1139 A novel assay reveals the blockade of esterases by piperonyl butoxide
Ryu_2008_Front.Biosci_13_777 Development of Alzheimer's disease imaging agents for clinical studies
Khan_2008_Chem.Biol.Interact_175_231 Pharmacological effects of a novel isosorbide-based butyrylcholinesterase inhibitor
Moriarty_2008_J.Med.Chem_51_7991 Discovery of a true aspirin prodrug
Wei_2008_Appl.Biochem.Biotechnol_149_79 Screening and immobilization Burkholderia sp. GXU56 lipase for enantioselective resolution of (R,S)-methyl mandelate
Stojan_2008_Biochemistry_47_5599 Evidence for subdomain flexibility in Drosophila melanogaster acetylcholinesterase
DeMartino_2008_Bioorg.Med.Chem.Lett_18_5842 Exploration of a fundamental substituent effect of alpha-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase
Brady_2008_BMC.Biotechnol_8_8 Spherezymes: a novel structured self-immobilisation enzyme technology
Ribelles_2008_Curr.Drug.Metab_9_336 A carboxylesterase 2 gene polymorphism as predictor of capecitabine on response and time to progression
Kassa_2008_Drug.Chem.Toxicol_31_371 A comparison of the therapeutic and reactivating efficacy of newly developed oximes (K117, K127) and currently available oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice
da Silva_2008_Neurotoxicol_29_184 Temporal effects of newly developed oximes (K027, K048) on malathion-induced acetylcholinesterase inhibition and lipid peroxidation in mouse prefrontal cortex
Musilek_2008_J.Enzyme.Inhib.Med.Chem_23_70 Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase
Kassa_2008_Toxicology_243_311 An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice
Kassa_2008_Chem.Biol.Interact_175_425 A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in soman, cyclosarin and tabun-poisoned rats
Berend_2008_Chem.Biol.Interact_175_413 New bispyridinium oximes: in vitro and in vivo evaluation of their biological efficiency in soman and tabun poisoning
Kassa_2008_Mini.Rev.Med.Chem_8_1134 The development of new oximes and the evaluation of their reactivating, therapeutic and neuroprotective efficacy against tabun
Kovarik_2008_Chem.Biol.Interact_175_173 Oximes: Reactivators of phosphorylated acetylcholinesterase and antidotes in therapy against tabun poisoning
Calic_2008_Chem.Biol.Interact_175_305 Interactions of butane, but-2-ene or xylene-like linked bispyridinium para-aldoximes with native and tabun-inhibited human cholinesterases
Vyas_2008_Chem.Biol.Interact_175_187 Reactivation of model cholinesterases by oximes and intermediate phosphyloximes: a computational study
Lorke_2008_J.Appl.Toxicol_28_920 Eight new bispyridinium oximes in comparison with the conventional oximes pralidoxime and obidoxime: in vivo efficacy to protect from diisopropylfluorophosphate toxicity
Gutierrez_2008_Proc.Natl.Acad.Sci.U.S.A_105_6320 Ghrelin octanoylation mediated by an orphan lipid transferase
Li_2008_Chem.Biol.Interact_175_88 The butyrylcholinesterase knockout mouse is obese on a high-fat diet
Gazic_2008_Anal.Bioanal.Chem_385_1513 Preparative HPLC separation of bambuterol enantiomers and stereoselective inhibition of human cholinesterases
Lopez_2008_J.Pestic.Sci_33_261 Adult vial bioassays of insecticidal toxicity against cotton fleahopper, Pseudatomoscelis seriatus (Hemiptera: Miridae)
Conde_2008_J.Pestic.Sci_33_51 Application of commercially available fenitrothion-ELISA kit for soil residue analysis
Rosell_2008_J.Pestic.Sci_33_103 Biorational insecticides in pest management
Sullivan_2008_J.Pestic.Sci_33_339 Environmental fate and properties of pyriproxyfen
Thanispong_2008_J.Pestic.Sci_33_351 Insecticide resistance of Aedes aegypti and Culex quinquefasciatus in Thailand
Tamura_2008_J.Pestic.Sci_33_33 Endocrine disruptors that disrupt the transcription mediated by androgen receptor
Joo_2008_J.Pestic.Sci_33_376 Imazamethabenz hydrolysis on oxide surfaces at several pH
Scott_2008_J.Pestic.Sci_33_221 Unraveling the mystery of spinosad resistance in insects
Cohen_2008_Hippocampus_18_182 Transgenic inactivation of acetylcholinesterase impairs homeostasis in mouse hippocampal granule cells
Shapira-Lichter_2008_Brain.Behav.Immun_22_388 Cytokines and cholinergic signals co-modulate surgical stress-induced changes in mood and memory
Cachard-Chastel_2008_Behav.Brain.Res_187_455 Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl\/6j mice
Machreki-Ajmi_2008_Ecotoxicology_17_1 The effect of in situ cadmium contamination on some biomarkers in Cerastoderma glaucum
Mumford_2008_J.Appl.Toxicol_28_694 A novel approach to assessing percutaneous VX poisoning in the conscious guinea-pig
Berson_2008_Brain_131_109 Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology
Zimmerman_2008_Eur.J.Neurosci_27_965 Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats
Podoly_2008_Neurodegener.Dis_5_232 Human recombinant butyrylcholinesterase purified from the milk of transgenic goats interacts with beta-amyloid fibrils and suppresses their formation in vitro
Soreq_2008_PLoS.ONE_3_e2392 Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays
Mor_2008_Chem.Biol.Interact_175_11 Alternate AChE-R variants facilitate cellular metabolic activity and resistance to genotoxic stress through enolase and RACK1 interactions
Dyck_2008_Exp.Dermatol_17_629 The role of the cutaneous cholinergic system in guttate psoriasis
Dierckx_2008_Acta.Clin.Belg_63_339 Donepezil-related toxic hepatitis
Alisky_2008_Neuropsychiatr.Dis.Treat_4_831 Intrathecal corticosteroids might slow Alzheimer's disease progression
Rozzini_2008_Aging.Clin.Exp.Res_20_509 Serum albumin level interferes with the effect of Donepezil in Alzheimer's disease
Sonohara_2008_Nippon.Ronen.Igakkai.Zasshi_45_615 [Localized cerebral blood flow changes in response to ADL-related vitality in elderly patients with dementia using single photon emission computed tomography]
Caixeta_2008_Rev.Bras.Psiquiatr_30_375 [Dementia in Parkinsn's disease.]
Feng_2008_Pestic.Biochem.Physiol_92_107 Effects of trichlorfon and sodium dodecyl sulphate on antioxidant defense system and acetylcholinesterase of Tilapia nilotica in vitro
Lasram_2008_Pestic.Biochem.Physiol_92_114 Effect of short-time malathion administration on glucose homeostasis in Wistar rat
Cattaneo_2008_Pestic.Biochem.Physiol_92_133 Metabolic and histological parameters of silver catfish (Rhamdia quelen) exposed to commercial formulation of 2,4-dichlorophenoxiacetic acid (2,4-D) herbicide
Buyukokuroglu_2008_Pestic.Biochem.Physiol_92_156 Dantrolene may prevent organophosphate-induced oxidative stress and muscle injury
Isik_2008_Pestic.Biochem.Physiol_92_38 Acute effects of methyl parathion and diazinon as inducers for oxidative stress on certain biomarkers in various tissues of rainbowtrout (Oncorhynchus mykiss)
Elhalwagy_2008_Pestic.Biochem.Physiol_91_81 Prophylactic effect of green tea polyphenols against liver and kidney injury induced by fenitrothion insecticide
Mahjoubi-Samet_2008_Pestic.Biochem.Physiol_91_96 Nephrotoxicity induced by dimethoate in adult rats and their suckling pups
Podolska_2008_Pestic.Biochem.Physiol_91_104 The impact of carbofuran on acetylcholinesterase activity in Anisakis simplex larvae from Baltic herring
Liu_2008_Pestic.Biochem.Physiol_91_45 Effects of temperature on fitness costs, insecticide susceptibility and heat shock protein in insecticide-resistant and -susceptible Plutella xylostella
Cao_2008_Pestic.Biochem.Physiol_90_175 Overexpression of carboxylesterase gene associated with organophosphorous insecticide resistance in cotton aphids, Aphis gossypii (Glover)
Kamath_2008_Pestic.Biochem.Physiol_90_58 Dimethoate induced biochemical perturbations in rat pancreas and its attenuation by cashew nut skin extract
Smith_2008_Aquaculture_280_5 A review of cyanobacterial odorous and bioactive metabolites: Impacts and management alternatives in aquaculture
Ramanujam_2008_Aquaculture_283_77 Effect of alcohol extract of a natural piscicide -- Fruits of Zanthoxylum armatum DC. on Mg2+- and Na+, K+-ATPase activity in various tissues of a freshwater air-breathing fish, Heteropneustes fossilis
Lund_2008_Aquaculture_276_143 The influence of dietary concentrations of arachidonic acid and eicosapentaenoic acid at various stages of larval ontogeny on eye migration, pigmentation and prostaglandin content of common sole larvae (Solea solea L.)
Bielza_2008_Pest.Manag.Sci_64_1131 Insecticide resistance management strategies against the western flower thrips, Frankliniella occidentalis
Bingham_2008_Pest.Manag.Sci_64_81 Temporal synergism can enhance carbamate and neonicotinoid insecticidal activity against resistant crop pests
Foster_2008_Pest.Manag.Sci_64_1111 Correlated responses to neonicotinoid insecticides in clones of the peach-potato aphid, Myzus persicae (Hemiptera: Aphididae)
Hodgson_2008_Pest.Manag.Sci_64_617 Metabolic interactions of agrochemicals in humans
Jones_2008_Pest.Manag.Sci_64_12 High-throughput allelic discrimination of B and Q biotypes of the whitefly, Bemisia tabaci, using TaqMan allele-selective PCR
Lapez-Soler_2008_Pest.Manag.Sci_64_1258 Esterase isoenzymes and insecticide resistance in Frankliniella occidentalis populations from the south-east region of Spain
Margaritopoulos_2008_Pest.Manag.Sci_64_900 Efficacy of the pyrethroid alpha-cypermethrin against Bactrocera oleae populations from Greece, and improved diagnostic for an iAChE mutation
Nauen_2008_Pest.Manag.Sci_64_1106 Age-specific expression of resistance to a neonicotinoid insecticide in the whitefly Bemisia tabaci
Paula_2008_Pest.Manag.Sci_64_863 Synthesis and insecticidal activity of new 3-benzylfuran-2-yl N,N,N,N-tetraethyldiamidophosphate derivatives
Qureshi_2008_Pest.Manag.Sci_64_1159 Rate, placement and timing of aldicarb applications to control Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), in oranges
Soleao_2008_Pest.Manag.Sci_64_964 Toxicological and biochemical response to azinphos-methyl in Cydia pomonella L. (Lepidoptera: Tortricidae) among orchards from the Argentinian Patagonia
Zhang_2008_Pest.Manag.Sci_64_185 Inheritance of beta-cypermethrin resistance in the housefly Musca domestica (Diptera: Muscidae)
Cho_2008_J.Asia.Pac.Entomol_11_117 Kdr allelic variation in a sodium channel gene from a population of South Carolina Heliothis virescens (Fabricius)
Prabhu_2008_Indian.J.Clin.Biochem_23_98 A preliminary study of protein thiols and serum cholinesterase in assisted reproduction
Bruno_2008_Biochem.Biophys.Res.Commun_369_1125 Clinical and genetic characterization of Chanarin-Dorfman syndrome.
Dackovic_2008_Acta.Myol_27_59 Hereditary motor and sensory neuropathy Lom type in a Serbian family
Haldorsen_2008_Diabet.Med_25_782 Lack of pancreatic body and tail in HNF1B mutation carriers
Vesterhus_2008_J.Clin.Endocrinol.Metab_93_3505 Reduced pancreatic volume in hepatocyte nuclear factor 1A-maturity-onset diabetes of the young
Smirnov_2008_Dokl.Biochem.Biophys_420_105 The antiidiotypic approach to obtaining a proteolytic antibody
Cotes_2008_Appl.Microbiol.Biotechnol_78_741 Lipolytic enzymes in Mycobacterium tuberculosis
Coutard_2008_Protein.Expr.Purif_61_184 Green fluorescent protein and factorial approach: an effective partnership for screening the soluble expression of recombinant proteins in Escherichia coli
Alfa_2008_Mol.Cell.Neurosci_39_400 Isoform-specific contribution of protein kinase C to prion processing
Aluigi_2008_Cell.Biol.Toxicol_24_587 The sea urchin, Paracentrotus lividus, embryo as a bioethical model for neurodevelopmental toxicity testing: effects of diazinon on the intracellular distribution of OTX2-like proteins
Bouzat_2008_J.Neurosci_28_7808 The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization
Engel_2008_Ann.N.Y.Acad.Sci_1132_104 Further observations in congenital myasthenic syndromes
Falugi_2008_Birth.Defects.Res.C.Embryo.Today_84_188 Sea urchin development: an alternative model for mechanistic understanding of neurodevelopment and neurotoxicity
Hansen_2008_J.Biol.Chem_283_36066 An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance
Kracun_2008_Br.J.Pharmacol_153_1474 Influence of the M3-M4 intracellular domain upon nicotinic acetylcholine receptor assembly, targeting and function
Lansdell_2008_J.Neurochem_105_1573 Host-cell specific effects of the nicotinic acetylcholine receptor chaperone RIC-3 revealed by a comparison of human and Drosophila RIC-3 homologues
Lee_2008_J.Gen.Physiol_132_265 Nicotinic receptor interloop proline anchors beta1-beta2 and Cys loops in coupling agonist binding to channel gating
Millar_2008_Br.J.Pharmacol_153 Suppl 1_S177 RIC-3: a nicotinic acetylcholine receptor chaperone
Millar_2008_Mol.Membr.Biol_25_279 Assembly and trafficking of nicotinic acetylcholine receptors (Review)
Rao_2008_Bioinform.Biol.Insights_2_1 Proteomic analysis in diabetic cardiomyopathy using bioinformatics approach
Rao_2008_Med.Hypotheses_70_148 Bioinformatics analysis of diabetic retinopathy using functional protein sequences
Schutz_2008_Neurosci_156_310 Sweat gland innervation is pioneered by sympathetic neurons expressing a cholinergic\/noradrenergic co-phenotype in the mouse
Shen_2008_J.Clin.Invest_118_1867 Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating
Sine_2008_Ann.N.Y.Acad.Sci_1132_53 Recent structural and mechanistic insights into endplate acetylcholine receptors
Slack_2008_J.Cell.Biochem_104_1818 Differential regulation of mTOR-dependent S6 phosphorylation by muscarinic acetylcholine receptor subtypes
Wang_2008_PLoS.Comput.Biol_4_e41 Control of cation permeation through the nicotinic receptor channel
Wu_2008_Mol.Pharmacol_74_466 Morantel allosterically enhances channel gating of neuronal nicotinic acetylcholine alpha 3 beta 2 receptors
Young_2008_Proc.Natl.Acad.Sci.U.S.A_105_14686 Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site
Chacon_2008_J.Cell.Physiol_217_215 Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers
Krnjevic_2008_Neuropharmacol_55_319 Electrophysiology of cerebral ischemia
Monchanin_2008_Clin.Hemorheol.Microcirc_40_89 Plasma levels of adhesion molecules ICAM-1 and VCAM-1 in athletes with sickle cell trait with or without alpha-thalassemia during endurance exercise and recovery
Patinkin_2008_Eur.J.Pharmacol_595_1 Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation
Rebolledo_2008_Mol.Neurobiol_38_178 Inclusion body myositis: a view from the Caenorhabditis elegans muscle
Xue_2008_Prog.Neuropsychopharmacol.Biol.Psychiatry_32_1131 Tobacco\/nicotine and endogenous brain opioids
Dhamija_2008_Clin.Gastroenterol.Hepatol_6_988 Serologic profiles aiding the diagnosis of autoimmune gastrointestinal dysmotility
Drenan_2008_Neuron_60_123 In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors
Drenan_2008_Mol.Pharmacol_73_27 Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled alpha6 and beta3 subunits
Gleitsman_2008_J.Biol.Chem_283_35638 An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating
Hanek_2008_J.Am.Chem.Soc_130_13216 A stereochemical test of a proposed structural feature of the nicotinic acetylcholine receptor
Kawai_2008_Biochem.Biophys.Res.Commun_366_834 Epibatidine binds to four sites on the Torpedo nicotinic acetylcholine receptor
Ruff_2008_J.Neuroimmunol_201-202_13 How myasthenia gravis alters the safety factor for neuromuscular transmission
Shao_2008_J.Neurosci_28_519 Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic\/nicotinic modulation of respiratory rhythm
Guidine_2008_Neurosci.Lett_436_201 Vesicular acetylcholine transporter knock-down mice are more susceptible to pilocarpine induced status epilepticus
Faria_2008_Nucleosides.Nucleotides.Nucleic.Acids_27_761 Decreased ecto-NTPDase1\/CD39 activity leads to desensitization of P2 purinoceptors regulating tonus of corpora cavernosa in impotent men with endothelial dysfunction
Moroni_2008_J.Neurosci_28_6884 Non-agonist-binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the alpha4beta2 nicotinic receptor: an alpha4-alpha4 interface is required for Zn2+ potentiation
Osipov_2008_J.Biol.Chem_283_14571 Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification
Timoteo_2008_Neurochem.Int_52_834 Tuning adenosine A1 and A2A receptors activation mediates L-citrulline-induced inhibition of [3H]-acetylcholine release depending on nerve stimulation pattern
Zwart_2008_Mol.Pharmacol_73_1838 Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors
Boss_2008_J.Magn.Reson.Imaging_28_1510 Measurement of T1, T2, and magnetization transfer properties during embryonic development at 7 Tesla using the chicken model
Chan_2008_Proc.Natl.Acad.Sci.U.S.A_105_10978 Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia
Ogier_2008_Eur.J.Neurosci_28_924 Pudendal motoneurons of the rat located in separated spinal nuclei possess nicotinic acetylcholine receptors having distinct pharmacological profiles
Cohen_2008_Brain.Res_1235_21 Determinants of spontaneous activity in networks of cultured hippocampus
Treinin_2008_Biotechnol.J_3_1539 RIC-3 and nicotinic acetylcholine receptors: biogenesis, properties, and diversity
Yi_2008_Mol.Immunol_46_192 Suppression of experimental myasthenia gravis by a B-cell epitope-free recombinant acetylcholine receptor
Akasofu_2008_Eur.J.Pharmacol_588_189 Donepezil attenuates excitotoxic damage induced by membrane depolarization of cortical neurons exposed to veratridine
Bruneau_2008_Curr.Biol_18_109 Acetylcholine receptor clustering is required for the accumulation and maintenance of scaffolding proteins
Chandra_2008_Neurochem.Int_52_376 Effect of novel arecoline thiazolidinones as muscarinic receptor 1 agonist in Alzheimer's dementia models
Coleman_2008_Chem.Biol.Interact_175_387 [+]-Huperzine A treatment protects against N-methyl-D-aspartate-induced seizure\/status epilepticus in rats
Geng_2008_Chem.Biol.Interact_175_108 Transmembrane mechanisms in the assembly of the postsynaptic apparatus at the neuromuscular junction
Kumar_2008_J.Enzyme.Inhib.Med.Chem_23_462 Synthesis and antimicrobial studies of novel 1-benzhydryl-piperazine sulfonamide and carboxamide derivatives
Kumar_2008_Bioorg.Med.Chem_16_5157 Effect of novel N-aryl sulfonamide substituted 3-morpholino arecoline derivatives as muscarinic receptor 1 agonists in Alzheimer's dementia models
Lee_2008_Mol.Biol.Cell_19_150 The function of mitochondria in presynaptic development at the neuromuscular junction
Maiti_2008_Behav.Brain.Res_189_233 Hypobaric hypoxia induces dendritic plasticity in cortical and hippocampal pyramidal neurons in rat brain
Maiti_2008_J.Chem.Neuroanat_36_227 High altitude memory impairment is due to neuronal apoptosis in hippocampus, cortex and striatum
Qian_2008_BMC.Neurosci_9_70 The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters
Shi_2008_J.Cell.Biochem_105_129 Un-nicked BoNT\/B activity in human SHSY-5Y neuronal cells
Brady_2008_J.Pharmacol.Exp.Ther_327_941 Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats
Bridges_2008_Bioorg.Med.Chem.Lett_18_5439 Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties
Burgdorf_2008_J.Comp.Psychol_122_357 Ultrasonic vocalizations of rats (Rattus norvegicus) during mating, play, and aggression: Behavioral concomitants, relationship to reward, and self-administration of playback
Cahoy_2008_J.Neurosci_28_264 A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function
Ellerton_2008_Neurosci_153_975 Induction of zinc-finger proliferation 1 expression in non-myelinating Schwann cells after denervation
Favero_2008_J.Physiol_586_4763 Expression of small-conductance calcium-activated potassium channels (SK3) in skeletal muscle: regulation by muscle activity
Griffin_2008_Glia_56_1518 Biology and pathology of nonmyelinating Schwann cells
Hamouda_2008_Biochemistry_47_12787 Probing the structure of the affinity-purified and lipid-reconstituted torpedo nicotinic acetylcholine receptor
Hansen_2008_J.Med.Chem_51_7380 Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist
Harmon_2008_Dev.Psychobiol_50_322 Rats selectively bred for low levels of 50 kHz ultrasonic vocalizations exhibit alterations in early social motivation
Hawes_2008_Neuropsychopharmacology_33_1864 Galanin protects against behavioral and neurochemical correlates of opiate reward
Jones_2008_J.Neurosci_28_10422 Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
Picciotto_2008_Prog.Neurobiol_84_329 It is not either\/or: activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood
Sanghvi_2008_Biochim.Biophys.Acta_1778_2690 Identifying the binding site(s) for antidepressants on the Torpedo nicotinic acetylcholine receptor: [3H]2-azidoimipramine photolabeling and molecular dynamics studies
Zhang_2008_Neuron_60_285 LRP4 serves as a coreceptor of agrin
Castelan_2008_J.Neurochem_105_617 Molecular characterization and localization of the RIC-3 protein, an effector of nicotinic acetylcholine receptor expression
Criado_2008_J.Neurochem_104_719 Interactions between loop 5 and beta-strand beta6' are involved in alpha7 nicotinic acetylcholine receptors channel gating
Dobbins_2008_Mol.Brain_1_18 alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering
Faghih_2008_J.Med.Chem_51_701 Allosteric modulators of the alpha7 nicotinic acetylcholine receptor
Fruchart-Gaillard_2008_Mol.Pharmacol_74_1554 Different interactions between MT7 toxin and the human muscarinic M1 receptor in its free and N-methylscopolamine-occupied states
Gahring_2008_Hippocampus_18_737 Nicotinic acetylcholine receptor expression in the hippocampus of 27 mouse strains reveals novel inhibitory circuitry
Jakubik_2008_Physiol.Res_57 Suppl 3_S39 Importance and prospects for design of selective muscarinic agonists
Krieger_2008_Chembiochem_9_1146 Fluorescent agonists for the Torpedo nicotinic acetylcholine receptor
Liu_2008_Mol.Cell.Neurosci_38_236 EphB receptors co-distribute with a nicotinic receptor subtype and regulate nicotinic downstream signaling in neurons
Machova_2008_Neurobiol.Aging_29_368 Impairment of muscarinic transmission in transgenic APPswe\/PS1dE9 mice
Mourot_2008_J.Neurochem_105_413 Agonist- and competitive antagonist-induced movement of loop 5 on the alpha subunit of the neuronal alpha4beta4 nicotinic acetylcholine receptor
Nunes_2008_Biological.Bulletin_214_1 Acetylcholine release and choline uptake by cuttlefish (Sepia officinalis) optic lobe synaptosomes
Osborne-Hereford_2008_J.Neuroimmunol_193_130 Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation
Rodrigues_2008_Neurobiol.Aging_29_1597 Modification of adenosine modulation of acetylcholine release in the hippocampus of aged rats
Rogers_2008_Hippocampus_18_750 Mouse chromosome 11 harbors genetic determinants of hippocampal strain-specific nicotinic receptor expression
Sala_2008_Acta.Physiol.(Oxf)_192_203 Nicotinic acetylcholine receptors of adrenal chromaffin cells
Searl_2008_J.Neurophysiol_99_2779 Mechanisms of neuromodulation as dissected using Sr2+ at motor nerve endings
Talley_2008_Proc.Natl.Acad.Sci.U.S.A_105_7606 Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore
Weiss_2008_PLoS.Genet_4_e1000125 A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction
Jankowska-Kulawy_2008_Acta.Neurobiol.Exp.(Wars)_68_453 Effects of lead on cholinergic SN56 neuroblastoma cells
Lendvai_2008_Physiol.Rev_88_333 Nonsynaptic chemical transmission through nicotinic acetylcholine receptors
Pehrson_2008_Pharmacol.Biochem.Behav_89_424 The effects of acute and repeated nicotine doses on spontaneous activity in male and female Sprague Dawley rats: analysis of brain area epibatidine binding and cotinine levels
Prus_2008_Pharmacol.Biochem.Behav_91_150 Acute nicotine reduces and repeated nicotine increases spontaneous activity in male and female Lewis rats
Rozsa_2008_Eur.J.Neurosci_27_364 Dendritic nicotinic receptors modulate backpropagating action potentials and long-term plasticity of interneurons
Szabo_2008_Hippocampus_18_376 The effect of nicotine on spiking activity and Ca2+ dynamics of dendritic spines in rat CA1 pyramidal neurons
Bell_2008_Neurobiol.Aging_29_554 ADAM-10 over-expression increases cortical synaptogenesis
Cymes_2008_Nat.Struct.Mol.Biol_15_389 Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer
Gay_2008_J.Physiol_586_1105 Aromatic residues at position 55 of rat alpha7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization
Gay_2008_J.Pharmacol.Exp.Ther_327_884 Inhibition of native and recombinant nicotinic acetylcholine receptors by the myristoylated alanine-rich C kinase substrate peptide
Ghedini_2008_Muscle.Nerve_38_1585 Increased expression of acetylcholine receptors in the diaphragm muscle of MDX mice
Hancock_2008_J.Gen.Physiol_131_i4 Presynaptic type III neuregulin1-ErbB signaling targets alpha7 nicotinic acetylcholine receptors to axons
Horenstein_2008_Mol.Pharmacol_74_1496 Multiple pharmacophores for the selective activation of nicotinic alpha7-type acetylcholine receptors
Jiang_2008_J.Neurophysiol_99_1988 Facilitation of cortico-amygdala synapses by nicotine: activity-dependent modulation of glutamatergic transmission
Mao_2008_J.Neurochem_104_446 The alpha4beta2alpha5 nicotinic cholinergic receptor in rat brain is resistant to up-regulation by nicotine in vivo
Poisik_2008_J.Physiol_586_1365 Functional alpha7-containing nicotinic acetylcholine receptors localize to cell bodies and proximal dendrites in the rat substantia nigra pars reticulata
Zhong_2008_J.Neurosci_28_9111 Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors
Bafna_2008_PLoS.One_3_e2515 Gating at the mouth of the acetylcholine receptor channel: energetic consequences of mutations in the alphaM2-cap
Cheung_2008_J.Biol.Chem_283_13762 Crystal structure of a functional dimer of the PhoQ sensor domain
Remelli_2008_J.Neurochem_104_1020 The C-terminus of the metabotropic glutamate receptor 1b regulates dimerization of the receptor
Aviram_2008_Methods.Mol.Biol_477_259 Paraoxonases (PON1, PON2, PON3) analyses in vitro and in vivo in relation to cardiovascular diseases
Aviram_2008_J.Agric.Food.Chem_56_1148 Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins
Bajnok_2008_Atherosclerosis_197_363 Relationship of adiponectin to serum paraoxonase 1
Bajnok_2008_Exp.Clin.Endocrinol.Diabetes_116_592 Relationship of serum resistin level to traits of metabolic syndrome and serum paraoxonase 1 activity in a population with a broad range of body mass index
Bodolay_2008_J.Rheumatol_35_237 Evaluation of paraoxonase activity in patients with mixed connective tissue disease
Connelly_2008_J.Lipid.Res_49_245 Development of an immunoblot assay with infrared fluorescence to quantify paraoxonase 1 in serum and plasma
Efrat_2008_Biochem.Biophys.Res.Commun_376_105 Macrophage paraoxonase 1 (PON1) binding sites
Fortunato_2008_Arterioscler.Thromb.Vasc.Biol_28_594 Decreased paraoxonase-2 expression in human carotids during the progression of atherosclerosis
Fuhrman_2008_Arterioscler.Thromb.Vasc.Biol_28_1361 Urokinase plasminogen activator upregulates paraoxonase 2 expression in macrophages via an NADPH oxidase-dependent mechanism
Harangi_2008_Cerebrovasc.Dis_25_122 Association between human paraoxonase 1 activity and intima-media thickness in subjects under 55 years of age with carotid artery disease
Kerekes_2008_J.Rheumatol_35_398 Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: a multiparametric analysis using imaging techniques and laboratory markers of inflammation and autoimmunity
Marchegiani_2008_Rejuvenation.Res_11_113 Paraoxonase 1: genetics and activities during aging
Mirdamadi_2008_Br.J.Clin.Pharmacol_66_366 The human paraoxonase-1 phenotype modifies the effect of statins on paraoxonase activity and lipid parameters
Moren_2008_J.Lipid.Res_49_1246 HDL subfraction distribution of paraoxonase-1 and its relevance to enzyme activity and resistance to oxidative stress
Reddy_2008_Curr.Opin.Lipidol_19_405 Is it just paraoxonase 1 or are other members of the paraoxonase gene family implicated in atherosclerosis?
Rock_2008_J.Agric.Food.Chem_56_8704 Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-density lipoprotein and stimulates its catalytic activities
Rosenblat_2008_J.Nutr.Biochem_19_514 Antiatherogenicity of extra virgin olive oil and its enrichment with green tea polyphenols in the atherosclerotic apolipoprotein-E-deficient mice: enhanced macrophage cholesterol efflux
Rozenberg_2008_Free.Radic.Biol.Med_44_1951 Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties
Tavori_2008_Bioorg.Med.Chem_16_7504 Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity
Teiber_2008_Infect.Immun_76_2512 Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone
van Himbergen_2008_Atherosclerosis_199_408 Paraoxonase (PON1) and the risk for coronary heart disease and myocardial infarction in a general population of Dutch women
van Himbergen_2008_Atherosclerosis_199_87 Paraoxonase (PON1) is associated with familial combined hyperlipidemia
Wetmur_2008_Methods.Mol.Biol_410_351 An emulsion polymerase chain reaction-based method for molecular haplotyping
Dronca_2008_Clin.Chem.Lab.Med_46_880 Serum paraoxonase 1 activities and homocysteinemia in hemodialysis patients
Ferretti_2008_Clin.Chem.Lab.Med_46_113 Lipid peroxidation in stroke patients
Ferretti_2008_Clin.Biochem_41_381 Lipid peroxidation in hemodialysis patients: effect of vitamin C supplementation
Kotur-Stevuljevic_2008_Clin.Biochem_41_1067 PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients
Zolese_2008_Biofactors_33_201 Effect of acylethanolamides on lipid peroxidation and paraoxonase activity
Aslan_2008_Int.J.Clin.Pract_62_1050 Serum paraoxonase and arylesterase activities for the evaluation of patients with chronic hepatitis
Aslan_2008_Atherosclerosis_196_270 Serum paraoxonase-1 activity in Helicobacter pylori infected subjects
Ece_2008_Clin.Rheumatol_27_163 Antioxidant enzyme activities, lipid peroxidation, and total antioxidant status in children with Henoch-Schonlein purpura
Gunay_2008_Cell.Biochem.Funct_26_747 Effects of a selective Rho-kinase inhibitor Y-27632 on oxidative stress parameters in acute dichlorvos poisoning in rats
Kilic_2008_Ann.Ophthalmol.(Skokie)_40_22 Protective effects of melatonin on oxidative-antioxidative balance and cataract formation in rats
Selek_2008_Clin.Biochem_41_140 PON1 activity and total oxidant status in patients with active pulmonary tuberculosis
Verit_2008_Redox.Rep_13_134 Paraoxonase-1 activity in patients with hyperemesis gravidarum
Verit_2008_Hum.Reprod_23_100 Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease
Yildiz_2008_Clin.Biochem_41_779 Paraoxonase and arylesterase activities in untreated dipper and non-dipper hypertensive patients
Yildiz_2008_Atherosclerosis_197_257 Association of paraoxonase activity and coronary blood flow
Yildiz_2008_Coron.Artery.Dis_19_441 Association of paraoxonase activity and coronary collateral flow
Nakou_2008_Expert.Opin.Pharmacother_9_3151 The effects of ezetimibe and orlistat, alone or in combination, on high-density lipoprotein (HDL) subclasses and HDL-associated enzyme activities in overweight and obese patients with hyperlipidaemia
Li_2008_J.Comp.Neurol_506_733 Neuroendocrine secretory protein 55 (NESP55) in the spinal cord of rat: an immunocytochemical study
Grinberg_2008_Chem.Phys.Lipids_153_85 Synthesis of novel cationic bolaamphiphiles from vernonia oil and their aggregated structures
Nelson_2008_J.Neurochem_107_602 Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons
Rosethorne_2008_Biochem.Pharmacol_75_942 Regulation of cyclic AMP response-element binding-protein (CREB) by Gq\/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells
Chew_2008_J.Am.Geriatr.Soc_56_1333 Anticholinergic activity of 107 medications commonly used by older adults
Sogorb_2008_Chem.Res.Toxicol_21_1524 Serum albumin is as efficient as paraxonase in the detoxication of paraoxon at toxicologically relevant concentrations
Haidet_2008_Proc.Natl.Acad.Sci.U.S.A_105_4318 Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors
Kim_2008_Mol.Cell.Neurosci_39_452 O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors
Martin_2008_Neuromuscul.Disord_18_942 Muscular dystrophy associated with alpha-dystroglycan deficiency in Sphynx and Devon Rex cats
Nwosu_2008_Neurosci.Lett_441_282 Impact of apoE deficiency during synaptic remodeling in the mouse olfactory bulb
Struble_2008_Front.Biosci_13_5387 Apolipoprotein E may be a critical factor in hormone therapy neuroprotection
Xiong_2008_Exp.Neurol_211_271 Doublecortin-expressing cells are present in layer II across the adult guinea pig cerebral cortex: partial colocalization with mature interneuron markers
Arredondo_2008_FASEB.J_22_1356 Receptor-mediated tobacco toxicity: acceleration of sequential expression of alpha5 and alpha7 nicotinic receptor subunits in oral keratinocytes exposed to cigarette smoke
Chernyavsky_2008_J.Biol.Chem_283_3401 Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis
Fujii_2008_J.Pharmacol.Sci_106_186 Basic and clinical aspects of non-neuronal acetylcholine: expression of an independent, non-neuronal cholinergic system in lymphocytes and its clinical significance in immunotherapy
Grando_2008_J.Pharmacol.Sci_106_174 Basic and clinical aspects of non-neuronal acetylcholine: biological and clinical significance of non-canonical ligands of epithelial nicotinic acetylcholine receptors
Kawashima_2008_J.Pharmacol.Sci_106_167 Basic and clinical aspects of non-neuronal acetylcholine: overview of non-neuronal cholinergic systems and their biological significance
Kishi_2008_Ann.N.Y.Acad.Sci_1139_70 Alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes are not associated with methamphetamine-use disorder in the Japanese population
Kishi_2008_J.Neural.Transm_115_1457 Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population
Michael_2008_Curr.Dir.Autoimmun_10_333 Novel mechanism for therapeutic action of IVIg in autoimmune blistering dermatoses
Misawa_2008_Eur.J.Neurosci_27_3109 Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient mice
Wessler_2008_Br.J.Pharmacol_154_1558 Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans
Jiang_2008_J.Pharmacol.Exp.Ther_326_330 Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells
Svizenska_2008_Pharmacol.Biochem.Behav_90_501 Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures--a short review
Beck_2008_Nat.Rev.Neurosci_9_357 Plasticity of intrinsic neuronal properties in CNS disorders
Dresbach_2008_Histochem.Cell.Biol_130_617 Molecular architecture of glycinergic synapses
Gekel_2008_J.Neurosci_28_7991 Application of an Epac activator enhances neurotransmitter release at excitatory central synapses
Jin_2008_FEBS.J_275_2042 Changes in acetylcholine receptor function induce shifts in muscle fiber type composition
Kupchik_2008_Proc.Natl.Acad.Sci.U.S.A_105_4435 Molecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release
Lau_2008_Eur.J.Pharmacol_578_137 The cannabinoid CB1 receptor is expressed on serotonergic and dopaminergic neurons
Li_2008_Mol.Neurobiol_37_164 Acetylcholine receptor gamma-subunits mRNA isoforms expressed in denervated rat muscle
Morales_2008_Neurosci_152_70 Hippocampal interneurons co-express transcripts encoding the alpha7 nicotinic receptor subunit and the cannabinoid receptor 1
Neher_2008_Neuron_59_861 Multiple roles of calcium ions in the regulation of neurotransmitter release
Pauly_2008_PLoS.One_3_e2681 Activity-dependent shedding of the NMDA receptor glycine binding site by matrix metalloproteinase 3: a PUTATIVE mechanism of postsynaptic plasticity
Roder_2008_PLoS.One_3_e3871 Role of Myosin Va in the plasticity of the vertebrate neuromuscular junction in vivo
Stroud_2008_Protein.Sci_17_1864 Michael A. Raftery (1936-2007)--the first enzyme mechanism, sequential cooperativity, and the nicotinic acetylcholine receptor defined
Teichert_2008_Ann.N.Y.Acad.Sci_1132_61 Peptide-toxin tools for probing the expression and function of fetal and adult subtypes of the nicotinic acetylcholine receptor
Tzartos_2008_Ann.N.Y.Acad.Sci_1132_291 Antigen-specific apheresis of pathogenic autoantibodies from myasthenia gravis sera
Wang_2008_J.Neurosci_28_14450 Synaptic vesicles in mature calyx of Held synapses sense higher nanodomain calcium concentrations during action potential-evoked glutamate release
Yampolsky_2008_Mol.Cell.Neurosci_37_634 AChR channel conversion and AChR-adjusted neuronal survival during embryonic development
Yu_2008_Proc.Natl.Acad.Sci.U.S.A_105_16003 Role of Rab27 in synaptic transmission at the squid giant synapse
Zisimopoulou_2008_J.Neuroimmunol_201-202_95 Towards antigen-specific apheresis of pathogenic autoantibodies as a further step in the treatment of myasthenia gravis by plasmapheresis
Brkic_2008_Environ.Toxicol.Pharmacol_25_334 Carbofuran in water: Subchronic toxicity to rats
Li_2008_Chem.Res.Toxicol_21_421 Binding and hydrolysis of soman by human serum albumin
Lockridge_2008_J.Biol.Chem_283_22582 Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines
Lukomskaya_2008_Neurosci.Behav.Physiol_38_421 Involvement of ionotropic glutamate receptors in the appearance of arecoline tremor in mice
Wang_2008_Cell.Mol.Neurobiol_28_245 Pharmacodynamic study of FS-0311: a novel highly potent, selective acetylcholinesterase inhibitor
Weber_2008_Clin.Lab.Med_28_499 Pharmacogenetics: from description to prediction
Franco-Pons_2008_J.Gastrointest.Surg_12_891 Serum paraoxonase undergoes inhibition and proteolysis during experimental acute pancreatitis
Marsillach_2008_Free.Radic.Biol.Med_45_146 Immunohistochemical analysis of paraoxonases-1, 2, and 3 expression in normal mouse tissues
Brischoux_2008_J.Comp.Neurol_510_607 Muscarinic-2 and orexin-2 receptors on GABAergic and other neurons in the rat mesopontine tegmentum and their potential role in sleep-wake state control
Henny_2008_Eur.J.Neurosci_27_654 Projections from basal forebrain to prefrontal cortex comprise cholinergic, GABAergic and glutamatergic inputs to pyramidal cells or interneurons
Jones_2008_Ann.N.Y.Acad.Sci_1129_26 Modulation of cortical activation and behavioral arousal by cholinergic and orexinergic systems
Losen_2008_Ann.N.Y.Acad.Sci_1132_174 Treatment of myasthenia gravis by preventing acetylcholine receptor modulation
Richter_2008_Circ.Cardiovasc.Genet_1_147 Determination of paraoxonase 1 status without the use of toxic organophosphate substrates
Wills_2008_Neurology_70_929 Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS
Sanki_2008_Bioorg.Med.Chem_16_5672 Synthesis of methyl 5-S-alkyl-5-thio-D-arabinofuranosides and evaluation of their antimycobacterial activity
Abin-Carriquiry_2008_Eur.J.Pharmacol_589_80 In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: implications for Parkinson's Disease
Alout_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_271 Comparison of Anopheles gambiae and Culex pipiens acetycholinesterase 1 biochemical properties
Avale_2008_Proc.Natl.Acad.Sci.U.S.A_105_15991 Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion
Ben_2008_J.Econ.Entomol_101_484 Characterization of a novel high-activity esterase in Tunisian populations of the mosquito Culex pipiens
Berticat_2008_BMC.Evol.Biol_8_104 Costs and benefits of multiple resistance to insecticides for Culex quinquefasciatus mosquitoes
Chen_2008_J.Neurosci_28_6872 Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components
Dickinson_2008_Mol.Pharmacol_74_348 Presynaptic alpha 7- and beta 2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms
Fowler_2008_Behav.Pharmacol_19_461 Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice
Fujiyoshi_2008_Curr.Opin.Struct.Biol_18_587 Electron crystallography of proteins in membranes
Gotti_2008_Mol.Pharmacol_73_1796 Partial deletion of the nicotinic cholinergic receptor alpha 4 or beta 2 subunit genes changes the acetylcholine sensitivity of receptor-mediated 86Rb+ efflux in cortex and thalamus and alters relative expression of alpha 4 and beta 2 subunits
Innocent_2008_J.Pharmacol.Exp.Ther_327_529 Alpha-conotoxin Arenatus IB[V11L,V16D] [corrected] is a potent and selective antagonist at rat and human native alpha7 nicotinic acetylcholine receptors
Lipovsek_2008_Neurosci.Lett_434_165 Properties of mutated murine alpha4beta2 nicotinic receptors linked to partial epilepsy
Maskos_2008_Br.J.Pharmacol_153 Suppl 1_S438 The cholinergic mesopontine tegmentum is a relatively neglected nicotinic master modulator of the dopaminergic system: relevance to drugs of abuse and pathology
Maubourguet_2008_PLoS.Comput.Biol_4_e1000229 Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration
Mineur_2008_Biochem.Pharmacol_75_323 Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
Murineddu_2008_Bioorg.Med.Chem.Lett_18_6147 Synthesis of 3,6-diazabicyclo[3.1.1]heptanes as novel ligands for neuronal nicotinic acetylcholine receptors
Picciotto_2008_Front.Biosci_13_492 Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease
Pons_2008_J.Neurosci_28_12318 Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration
Rizzi_2008_Bioorg.Med.Chem.Lett_18_4651 Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes
Vieyra-Reyes_2008_Brain.Res.Bull_77_13 Antidepressant-like effects of nicotine and transcranial magnetic stimulation in the olfactory bulbectomy rat model of depression
Vieyra-Reyes_2008_Neurosci.Lett_434_18 Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors
Wonnacott_2008_Br.J.Pharmacol_153 Suppl 1_S2 Gates and filters: unveiling the physiological roles of nicotinic acetylcholine receptors in dopaminergic transmission
Wonnacott_2008_IDrugs_11_256 Smoking cessation 2008
Abdrakhmanova_2008_Neuropharmacol_55_1287 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs
Amiri_2008_Mol.Pharmacol_73_1659 A role for Leu118 of loop E in agonist binding to the alpha 7 nicotinic acetylcholine receptor
Baenziger_2008_Mol.Pharmacol_73_880 Lipid composition alters drug action at the nicotinic acetylcholine receptor
Bierut_2008_Am.J.Psychiatry_165_1163 Variants in nicotinic receptors and risk for nicotine dependence
Brown_2008_SEB.Exp.Biol.Ser_60_79 Amyloid peptides and ion channel function in Drosophila models of Alzheimer's disease
Carswell_2008_J.Bacteriol_190_5650 Expression, purification, and structural characterization of CfrA, a putative iron transporter from Campylobacter jejuni
Dahlhaus_2008_J.Neurosci_28_10794 Notch1 signaling in pyramidal neurons regulates synaptic connectivity and experience-dependent modifications of acuity in the visual cortex
De Rosa_2008_Biochim.Biophys.Acta_1778_521 Subunit-selective role of the M3 transmembrane domain of the nicotinic acetylcholine receptor in channel gating
Exley_2008_Br.J.Pharmacol_153 Suppl 1_S283 Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission
Grucza_2008_Biol.Psychiatry_64_922 A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence
Gumilar_2008_Eur.J.Pharmacol_584_30 Tricyclic antidepressants inhibit homomeric Cys-loop receptors by acting at different conformational states
Ihara_2008_Invert.Neurosci_8_71 Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin
Ivy_2008_Bioorg.Med.Chem_16_746 Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs
Jackson_2008_J.Pharmacol.Exp.Ther_325_302 Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs
Jones_2008_Invert.Neurosci_8_41 The cys-loop ligand-gated ion channel gene superfamily of the nematode, Caenorhabditis elegans
Kang_2008_Nature_456_904 Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation
Kota_2008_Psychopharmacology.(Berl)_198_201 Age-dependent differences in nicotine reward and withdrawal in female mice
Lape_2008_Nature_454_722 On the nature of partial agonism in the nicotinic receptor superfamily
Liu_2008_Acta.Pharmacol.Sin_29_305 Agonist-induced hump current production in heterologously-expressed human alpha4beta2-nicotinic acetylcholine receptors
Merritt_2008_J.Pharmacol.Exp.Ther_326_483 The endogenous cannabinoid system modulates nicotine reward and dependence
Reese_2008_Aging.Cell_7_824 Selective induction of calcineurin activity and signaling by oligomeric amyloid beta
Saccone_2008_Bioinformatics_24_1805 Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence
Sellings_2008_Eur.J.Neurosci_28_342 Rewarding and aversive effects of nicotine are segregated within the nucleus accumbens
Sharma_2008_J.Neurosci_28_2563 Action potential-independent and nicotinic receptor-mediated concerted release of multiple quanta at hippocampal CA3-mossy fiber synapses
Sharma_2008_Curr.Med.Chem_15_2921 Nicotinic receptors containing the alpha7 subunit: a model for rational drug design
Sharma_2008_Subst.Abus_2008_81 Nicotinic Receptors: Role in Addiction and Other Disorders of the Brain
Song_2008_J.Pharmacol.Sci_106_180 Basic and clinical aspects of non-neuronal acetylcholine: expression of non-neuronal acetylcholine in lung cancer provides a new target for cancer therapy
Walsh_2008_J.Biol.Chem_283_6022 Up-regulation of nicotinic receptors by nicotine varies with receptor subtype
Carta_2008_Eur.J.Neurosci_27_1220 Long-term increase in GAD67 mRNA expression in the central amygdala of rats sensitized by drugs and stress
Maruta_2008_J.Neurochem_105_401 Lysophosphatidic acid-LPA1 receptor-Rho-Rho kinase-induced up-regulation of Nav1.7 sodium channel mRNA and protein in adrenal chromaffin cells: enhancement of 22Na+ influx, 45Ca2+ influx and catecholamine secretion
Miyata_2008_Ann.N.Y.Acad.Sci_1139_458 Psychosocial withdrawal characteristics of nicotine compared with alcohol and caffeine
Beeson_2008_Ann.N.Y.Acad.Sci_1132_99 Congenital myasthenic syndromes and the formation of the neuromuscular junction
Rogozhin_2008_J.Physiol_586_3163 Recovery of mouse neuromuscular junctions from single and repeated injections of botulinum neurotoxin A
Slater_2008_Handb.Clin.Neurol_91_27 Reliability of neuromuscular transmission and how it is maintained
Slater_2008_Ann.N.Y.Acad.Sci_1132_1 Structural factors influencing the efficacy of neuromuscular transmission
Hanson_2008_Brain.Res.Rev_57_77 Spontaneous rhythmic activity in early chick spinal cord influences distinct motor axon pathfinding decisions
Hsiao_2008_J.Neurophysiol_99_999 Zinc potentiates neuronal nicotinic receptors by increasing burst duration
Kariya_2008_Hum.Mol.Genet_17_2552 Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
Barkhimer_2008_Anal.Bioanal.Chem_392_651 Electrochemical detection of acetylcholine and choline: application to the quantitative nonradiochemical evaluation of choline transport
Doerig_2008_Trends.Parasitol_24_570 Protein kinases of malaria parasites: an update
Miller_2008_Bioorg.Med.Chem.Lett_18_5443 Synthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen
Shekhar_2008_Am.J.Psychiatry_165_1033 Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia
Shirey_2008_Nat.Chem.Biol_4_42 An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission
Suga_2008_J.Pharmacol.Exp.Ther_327_518 Use of acetylcholine mustard to study allosteric interactions at the M(2) muscarinic receptor
Thomas_2008_J.Pharmacol.Exp.Ther_327_365 G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists
Tobin_2008_Br.J.Pharmacol_153 Suppl 1_S167 G-protein-coupled receptor phosphorylation: where, when and by whom
Tobin_2008_Trends.Pharmacol.Sci_29_413 Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling
Valant_2008_J.Biol.Chem_283_29312 A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric\/allosteric ligand
Atri_2008_Alzheimer.Dis.Assoc.Disord_22_209 Long-term course and effectiveness of combination therapy in Alzheimer disease
Barnes_2008_Chest_134_1278 Emerging pharmacotherapies for COPD
Barnes_2008_Curr.Opin.Pharmacol_8_300 Frontrunners in novel pharmacotherapy of COPD
Gordienko_2008_Cell.Calcium_43_122 Sub-plasmalemmal [Ca2+]i upstroke in myocytes of the guinea-pig small intestine evoked by muscarinic stimulation: IP3R-mediated Ca2+ release induced by voltage-gated Ca2+ entry
Nathanson_2008_Pharmacol.Ther_119_33 Synthesis, trafficking, and localization of muscarinic acetylcholine receptors
Pedersen_2008_J.Allergy.Clin.Immunol_122_322 Airway responsiveness and inflammation in adolescent elite swimmers
Reiner_2008_Life.Sci_82_718 The internalization of the M2 and M4 muscarinic acetylcholine receptors involves distinct subsets of small G-proteins
Agelan_2008_ILAR.J_49_E8 Refinement in the management of the denervated canine urinary bladder using an abdominal vesicostomy
Amenta_2008_Curr.Med.Chem_15_488 Pathways of acetylcholine synthesis, transport and release as targets for treatment of adult-onset cognitive dysfunction
Avlani_2008_J.Pharmacol.Exp.Ther_325_927 The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions
Braverman_2008_J.Pharmacol.Exp.Ther_325_954 The use of occupation isoboles for analysis of a response mediated by two receptors: M2 and M3 muscarinic receptor subtype-induced mouse stomach contractions
Cheema_2008_J.Pharmacol.Exp.Ther_324_648 Cholesterol regulates volume-sensitive osmolyte efflux from human SH-SY5Y neuroblastoma cells following receptor activation
D'Agostino_2008_Br.J.Pharmacol_154_1611 Isolated porcine bronchi provide a reliable model for development of bronchodilator anti-muscarinic agents for human use
Foster_2008_J.Pharmacol.Exp.Ther_325_457 Activation of muscarinic cholinergic receptors on human SH-SY5Y neuroblastoma cells enhances both the influx and efflux of K+ under conditions of hypo-osmolarity
Frazier_2008_Naunyn.Schmiedebergs.Arch.Pharmacol_377_449 Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and beta-adrenoceptors
Nawaratne_2008_Mol.Pharmacol_74_1119 New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug)
Proskocil_2008_Environ.Health.Perspect_116_381 Antigen sensitization influences organophosphorus pesticide-induced airway hyperreactivity
Ricci_2008_Pulm.Pharmacol.Ther_21_79 Changes in muscarinic cholinergic receptor expression in human peripheral blood lymphocytes in allergic rhinitis patients
Tayebati_2008_Clin.Exp.Hypertens_30_732 Vesicular acetylcholine transporter (VAChT) in the brain of spontaneously hypertensive rats (SHR): effect of treatment with an acetylcholinesterase inhibitor
Van Dort_2008_Int.Anesthesiol.Clin_46_75 Neurochemical modulators of sleep and anesthetic states
Verhein_2008_Am.J.Respir.Cell.Mol.Biol_39_730 IL-1 receptors mediate persistent, but not acute, airway hyperreactivity to ozone in guinea pigs
Zhu_2008_Sleep_31_1629 Morphine increases acetylcholine release in the trigeminal nuclear complex
Endoh_2008_Circ.J_72_1915 Cardiac Ca2+ signaling and Ca2+ sensitizers
Kovac_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_294_G88 Temporal and spatial dynamics underlying capacitative calcium entry in human colonic smooth muscle
Liang_2008_Brain.Res_1231_6 Effect of a novel neurotensin analog, NT69L, on nicotine-induced alterations in monoamine levels in rat brain
Aggarwal_2008_Indian.J.Med.Sci_62_179 Role of hyoscine N-butyl bromide (HBB, buscopan) as labor analgesic
Bai_2008_EMBO.Rep_9_472 Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits
Fagerholm_2008_Br.J.Pharmacol_154_1287 alpha2A-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice
Ito_2008_Brain.Res_1201_78 Some gamma-motoneurons contain gamma-aminobutyric acid in the rat cervical spinal cord
Kocharyan_2008_J.Cereb.Blood.Flow.Metab_28_221 Specific subtypes of cortical GABA interneurons contribute to the neurovascular coupling response to basal forebrain stimulation
Larsson_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_294_G165 Pharmacological analysis of components of the change in transmural potential difference evoked by distension of rat proximal small intestine in vivo
Ma_2008_Biochem.Biophys.Res.Commun_374_128 Heterooligomers of the muscarinic receptor and G proteins purified from porcine atria
Mann_2008_Neuropharmacol_55_1147 Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
Nicolakakis_2008_J.Neurosci_28_9287 Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist
Redka_2008_Mol.Pharmacol_74_834 Binding of orthosteric ligands to the allosteric site of the M(2) muscarinic cholinergic receptor
Savontaus_2008_Eur.J.Pharmacol_578_359 Reduced blood glucose levels, increased insulin levels and improved glucose tolerance in alpha2A-adrenoceptor knockout mice
Shen_2008_J.Pharmacol.Exp.Ther_325_507 An estrogen metabolite, 2-methoxyestradiol, disrupts cardiac microtubules and unmasks muscarinic inhibition of calcium current
Todani_2008_Chudoku.Kenkyu_21_387 [Acute poisoning with neonicotinoid insecticide acetamiprid]
Varoli_2008_Med.Chem_4_121 Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of Diphenidol: novel M4 muscarinic receptor antagonists
Rahnasto_2008_Pharmacogenomics.J_8_328 Identification of inhibitors of the nicotine metabolising CYP2A6 enzyme--an in silico approach
Hernandez_2008_J.Physiol_586_1811 Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications
Mosser_2008_J.Mol.Signal_3_20 Differential role of beta-arrestin ubiquitination in agonist-promoted down-regulation of M1 vs M2 muscarinic acetylcholine receptors
Anderson_2008_J.Pharmacol.Exp.Ther_324_179 [3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]hept ane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain
Bertrand_2008_Mol.Pharmacol_74_1407 Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment
Betschmann_2008_Bioorg.Med.Chem.Lett_18_3848 Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists
Decker_2008_Expert.Opin.Drug.Discov_3_1027 The potential of neuronal nicotinic acetylcholine receptor agonists for treating CNS conditions
Donnelly-Roberts_2008_J.Pharmacol.Exp.Ther_324_409 Painful purinergic receptors
Florjancic_2008_Bioorg.Med.Chem.Lett_18_2089 Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists
Hu_2008_J.Neurochem_106_1371 Role of GSK-3beta activation and alpha7 nAChRs in Abeta(1-42)-induced tau phosphorylation in PC12 cells
Morytko_2008_Bioorg.Med.Chem.Lett_18_2093 Synthesis and in vitro activity of N'-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists
Nelson_2008_J.Med.Chem_51_3030 Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists
Tietje_2008_CNS.Neurosci.Ther_14_65 Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties
Waring_2008_Neurosci.Res_60_266 Analysis of gene expression profiles in rat hippocampus following treatment with nicotine and an alpha7 nAChR selective agonist
Acker_2008_Bioorg.Med.Chem.Lett_18_3611 Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity
Albayati_2008_Drug.Metab.Dispos_36_2024 Pharmacokinetics of the novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat
Beseler_2008_Environ.Health.Perspect_116_1713 Depression and pesticide exposures among private pesticide applicators enrolled in the Agricultural Health Study
Dumas_2008_Am.J.Geriatr.Psychiatry_16_272 Nicotinic versus muscarinic blockade alters verbal working memory-related brain activity in older women
Dwoskin_2008_J.Pharmacol.Exp.Ther_326_563 N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity
Fedi_2008_Neurology_71_795 Reduced striatal D1 receptor binding in autosomal dominant nocturnal frontal lobe epilepsy
Freedman_2008_Am.J.Psychiatry_165_1040 Initial phase 2 trial of a nicotinic agonist in schizophrenia
Hoda_2008_Mol.Pharmacol_74_379 Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathogenic nicotinic acetylcholine receptor beta-subunit mutations outside the ion channel pore
Jonkman_2008_Neuropsychopharmacology_33_2131 Spontaneous nicotine withdrawal potentiates the effects of stress in rats
Kamel_2008_Environ.Health.Perspect_116_943 Association of lead exposure with survival in amyotrophic lateral sclerosis
Liu_2008_Psychopharmacology.(Berl)_196_365 Cue-induced reinstatement of nicotine-seeking behavior in rats: effect of bupropion, persistence over repeated tests, and its dependence on training dose
Lockman_2008_J.Pharmacol.Exp.Ther_324_244 Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier
Markou_2008_Philos.Trans.R.Soc.Lond.B.Biol.Sci_363_3159 Review. Neurobiology of nicotine dependence
Palmatier_2008_Neuropharmacol_55_1425 The motivation to obtain nicotine-conditioned reinforcers depends on nicotine dose
Palmatier_2008_Neuropsychopharmacology_33_2139 Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine
Papke_2008_Neuropharmacol_54_1189 Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras
Paterson_2008_Nicotine.Tob.Res_10_995 Chronic bupropion differentially alters the reinforcing, reward-enhancing and conditioned motivational properties of nicotine in rats
Paterson_2008_Psychopharmacology.(Berl)_198_351 The effects of chronic versus acute desipramine on nicotine withdrawal and nicotine self-administration in the rat
Potter_2008_Pharmacol.Biochem.Behav_88_407 Acute nicotine improves cognitive deficits in young adults with attention-deficit\/hyperactivity disorder
Rahman_2008_CNS.Neurol.Disord.Drug.Targets_7_422 Neuronal nicotinic receptors as brain targets for pharmacotherapy of drug addiction
Rahman_2008_Eur.J.Pharmacol_601_103 The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens
Rahman_2008_Br.J.Pharmacol_153_792 Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo
Stoker_2008_Neuropharmacol_54_1223 Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL\/6J and BALB\/cByJ mice
Zhang_2008_Bioorg.Med.Chem.Lett_18_5753 Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release
Dunlop_2008_Expert.Opin.Drug.Discov_3_623 Functional screening of alpha7 nicotinic receptor ligands
Oke_2008_J.Leukoc.Biol_83_512 From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex
Parikh_2008_J.Neurosci_28_3769 Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex
Parrish_2008_Mol.Med_14_567 Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling
Roncarati_2008_Assay.Drug.Dev.Technol_6_181 Functional properties of alpha7 nicotinic acetylcholine receptors co-expressed with RIC-3 in a stable recombinant CHO-K1 cell line
Rosas-Ballina_2008_Proc.Natl.Acad.Sci.U.S.A_105_11008 Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia
Thomsen_2008_Neurosci_154_741 The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat
Waldburger_2008_Arthritis.Rheum_58_3439 Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor
Yeboah_2008_Kidney.Int_74_62 Cholinergic agonists attenuate renal ischemia-reperfusion injury in rats
Lin_2008_J.Neurosci_28_3333 The role of nerve- versus muscle-derived factors in mammalian neuromuscular junction formation
Lin_2008_Proc.Natl.Acad.Sci.U.S.A_105_11406 Muscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice
Bailey_2008_Prog.Brain.Res_169_179 Synaptic remodeling, synaptic growth and the storage of long-term memory in Aplysia
Bailey_2008_Learn.Mem_15_261 Galpha(i2) inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses
Huang_2008_Learn.Mem_15_603 Chronic nicotine exposure induces a long-lasting and pathway-specific facilitation of LTP in the amygdala
Huxley_2008_Biochem.Biophys.Res.Commun_369_34 Memories of early work on muscle contraction and regulation in the 1950's and 1960's
Kim_2008_Proc.Natl.Acad.Sci.U.S.A_105_9087 Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals
Miniaci_2008_Neuron_59_1024 Sustained CPEB-dependent local protein synthesis is required to stabilize synaptic growth for persistence of long-term facilitation in Aplysia
Nicholls_2008_Neuron_58_104 Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility
Puthanveettil_2008_Cell_135_960 A new component in synaptic plasticity: upregulation of kinesin in the neurons of the gill-withdrawal reflex
Faure_2008_Toxicon_52_400 Obituary: Cassian Bon a scientist fascinated by toxins and their therapeutic potential
Dougherty_2008_Neurochem.Res_33_1106 Chronic nicotine alters nicotinic receptor-induced presynaptic Ca2+ responses in isolated nerve terminals
Fujimoto_2008_Bioorg.Med.Chem.Lett_18_1106 Cy3-3-acylcholine: a fluorescent analogue of acetylcholine for single molecule detection
Giebelen_2008_J.Infect.Dis_198_750 Deficiency of alpha7 cholinergic receptors facilitates bacterial clearance in Escherichia coli peritonitis
Kabbani_2008_Proteomics_8_4146 Proteomics of membrane receptors and signaling
Kalinichev_2008_Behav.Pharmacol_19_71 Locomotor reactivity to a novel environment and sensitivity to MK-801 in five strains of mice
Kone_2008_Acta.Crystallogr.B_64_338 Hydrogen-bonding properties of galanthamine: an investigation through crystallographic database observations and computational chemistry
Le Foll_2008_Addict.Biol_13_239 Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies
Perry_2008_Insect.Biochem.Mol.Biol_38_520 Mutations in Dalpha1 or Dbeta2 nicotinic acetylcholine receptor subunits can confer resistance to neonicotinoids in Drosophila melanogaster
Putz_2008_J.Neurosci.Res_86_972 Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes
Scherma_2008_CNS.Neurol.Disord.Drug.Targets_7_468 The endocannabinoid system: a new molecular target for the treatment of tobacco addiction
Siehler_2008_Biotechnol.J_3_471 Cell-based assays in GPCR drug discovery
Sink_2008_Neuropsychopharmacology_33_946 The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats
Tang_2008_J.Nat.Prod_71_112 Alkaloids from stems and leaves of Stemona japonica and their insecticidal activities
Thany_2008_Neurosci.Lett_438_317 Effect of calcium on nicotine-induced current expressed by an atypical alpha-bungarotoxin-insensitive nAChR2
Boulin_2008_Proc.Natl.Acad.Sci.U.S.A_105_18590 Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor
Nilsson_2008_Genetics_179_375 Caenorhabditis elegans num-1 negatively regulates endocytic recycling
Robert_2008_Genetics_180_673 Gene conversion and end-joining-repair double-strand breaks in the Caenorhabditis elegans germline
Larsen_2008_Protein.Expr.Purif_62_90 Expression of Candida antarctica lipase B in Pichia pastoris and various Escherichia coli systems
de la Torre_2008_Biochim.Biophys.Acta_1782_82 Proliferative actions of muscarinic receptors expressed in macrophages derived from normal and tumor bearing mice
Ammiraju_2008_Plant.Cell_20_3191 Dynamic evolution of oryza genomes is revealed by comparative genomic analysis of a genus-wide vertical data set
Du_2008_Plant.J_56_653 Functional gene-mining for salt-tolerance genes with the power of Arabidopsis
Huang_2008_Plant.Physiol.Biochem_46_647 Manipulation of sinapine, choline and betaine accumulation in Arabidopsis seed: towards improving the nutritional value of the meal and enhancing the seedling performance under environmental stresses in oilseed crops
Kim_2008_Appl.Microbiol.Biotechnol_77_1041 Discovery of three novel lipase ( lipA1 , lipA2 , and lipA3) and lipase-specific chaperone ( lipB) genes present in Acinetobacter sp. DYL129
Lim_2008_Int.J.Syst.Evol.Microbiol_58_565 Burkholderia sediminicola sp. nov., isolated from freshwater sediment
Elkins_2008_Proc.Natl.Acad.Sci.U.S.A_105_8102 A korarchaeal genome reveals insights into the evolution of the Archaea
Davies_2008_Clin.Toxicol.(Phila)_46_880 Hypotension in severe dimethoate self-poisoning
Eckert_2008_Biochem.Pharmacol_75_698 Comparison of the oxime-induced reactivation of erythrocyte and muscle acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity
Eckert_2008_Biochem.Pharmacol_75_1561 Effects of oximes on rate of decarbamylation of human red blood cell AChE measured with two different methods
Eddleston_2008_Lancet_371_597 Management of acute organophosphorus pesticide poisoning
Eddleston_2008_QJM_101_467 Predicting outcome using butyrylcholinesterase activity in organophosphorus pesticide self-poisoning
Eyer_2008_Br.J.Clin.Pharmacol_66_451 Are we using the right dose? - a tale of mole and gram
Eyer_2008_Biochem.Pharmacol_75_2045 Reactions of isodimethoate with human red cell acetylcholinesterase
Heilmair_2008_Toxicol.Lett_181_19 Enzyme-based assay for quantification of chlorpyrifos oxon in human plasma
Herkert_2008_Toxicology_246_188 Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors
Teressa_2008_Biol.Proced.Online_10_58 Cell culture-based analysis of postsynaptic membrane assembly in muscle cells
Takada-Takatori_2008_Eur.J.Pharmacol_590_150 Mechanisms of alpha7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment
Takada-Takatori_2008_J.Neurosci.Res_86_3575 Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil
Hess_2008_Extremophiles_12_351 Extremely thermostable esterases from the thermoacidophilic euryarchaeon Picrophilus torridus
Ford_2008_J.Agric.Food.Chem_56_10168 Comparative metabolism and pharmacokinetics of seven neonicotinoid insecticides in spinach
Nomura_2008_Bioorg.Med.Chem.Lett_18_5875 Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels
Tomizawa_2008_J.Med.Chem_51_4213 Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche
Vose_2008_Toxicol.Appl.Pharmacol_232_376 Cellular function of neuropathy target esterase in lysophosphatidylcholine action
Joosen_2008_Neurochem.Res_33_308 Percutaneous exposure to VX: clinical signs, effects on brain acetylcholine levels and EEG
Kassam_2008_J.Neurosci_28_8756 Developmental excitation of corticothalamic neurons by nicotinic acetylcholine receptors
Stefan_2008_Proc.Natl.Acad.Sci.U.S.A_105_10768 An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
Wijeyesakere_2008_Acta.Crystallogr.Sect.E.Struct.Rep.Online_64_o1425 Diethyl [2,2,2-trifluoro-1-phenyl-sulfonyl-amino-1-(trifluoro-meth-yl)eth-yl]phospho-nate
Clark_2008_Front.Mol.Neurosci_1_8 DPP6 Localization in Brain Supports Function as a Kv4 Channel Associated Protein
Colinas_2008_J.Gen.Physiol_131_455 A role for DPPX modulating external TEA sensitivity of Kv4 channels
Kim_2008_J.Neurophysiol_100_1835 Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neurons
Pinthong_2008_Mol.Pharmacol_73_801 Activity and subcellular trafficking of the sodium-coupled choline transporter CHT is regulated acutely by peroxynitrite
Elias_2008_J.Mol.Biol_379_1017 Structural basis for natural lactonase and promiscuous phosphotriesterase activities
El Moustaine_2008_Febs.J_275_2021 Full-length prion protein aggregates to amyloid fibrils and spherical particles by distinct pathways
Torrent_2008_Biophys.J_94_4056 Distinct unfolding and refolding pathways of ribonuclease a revealed by heating and cooling temperature jumps
Liang_2008_Neurobiol.Learn.Mem_90_138 Nicotinic modulation of tone-evoked responses in auditory cortex reflects the strength of prior auditory learning
D'Souza_2008_Eur.Neuropsychopharmacol_18_628 Certain or uncertain cocaine expectations influence accumbens dopamine responses to self-administered cocaine and non-rewarded operant behavior
Rusted_2008_Psychopharmacology.(Berl)_196_83 Nicotine effects on retrieval-induced forgetting are not attributable to changes in arousal
Thiel_2008_Neurosci_152_381 Effects of the cholinergic agonist nicotine on reorienting of visual spatial attention and top-down attentional control
Coulson_2008_J.Neurosci_28_315 p75 neurotrophin receptor mediates neuronal cell death by activating GIRK channels through phosphatidylinositol 4,5-bisphosphate
Galindo-Charles_2008_Synapse_62_601 Serotoninergic dorsal raphe neurons possess functional postsynaptic nicotinic acetylcholine receptors
Lamotte d'Incamps_2008_J.Neurosci_28_14121 Four excitatory postsynaptic ionotropic receptors coactivated at the motoneuron-Renshaw cell synapse
Perez-Burgos_2008_Neurosci_155_1079 Muscarinic M(1) modulation of N and L types of calcium channels is mediated by protein kinase C in neostriatal neurons
Sotthibundhu_2008_J.Neurosci_28_3941 Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor
Theberge_2008_Bioorg.Med.Chem.Lett_18_6122 Potent benzimidazolone-based CGRP receptor antagonists
Underwood_2008_Int.J.Biochem.Cell.Biol_40_1664 The p75 neurotrophin receptor
Underwood_2008_Mol.Cell.Neurosci_37_346 Palmitoylation of the C-terminal fragment of p75(NTR) regulates death signaling and is required for subsequent cleavage by gamma-secretase
Choi_2008_J.Biol.Chem_283_11050 Constitutive and agonist-induced dimerizations of the P2Y1 receptor: relationship to internalization and scaffolding
Gatti-Lafranconi_2008_FEBS.Lett_582_2313 Unscrambling thermal stability and temperature adaptation in evolved variants of a cold-active lipase
El Hassani_2008_Arch.Environ.Contam.Toxicol_54_653 Effects of sublethal doses of acetamiprid and thiamethoxam on the behavior of the honeybee (Apis mellifera)
El Hassani_2008_Neurobiol.Learn.Mem_90_589 Inhibitory neurotransmission and olfactory memory in honeybees
Es-Salah_2008_Neuroreport_19_939 RNA editing regulates insect gamma-aminobutyric acid receptor function and insecticide sensitivity
Gautier_2008_J.Pharmacol.Exp.Ther_324_149 Calcium-activated potassium channels in insect pacemaker neurons as unexpected target site for the novel fumigant dimethyl disulfide
Dudai_2008_Neuron_57_24 Seymour Benzer (1921-2007)
Guitton_2008_Behav.Brain.Res_191_148 Taste-dependent sociophobia: when food and company do not mix
Haramati_2008_Neuropsychologia_46_1756 The posterior parietal cortex in recognition memory: a neuropsychological study
Hasson_2008_Neuron_57_452 Enhanced intersubject correlations during movie viewing correlate with successful episodic encoding
Mendelsohn_2008_Neuron_57_159 Mesmerizing memories: brain substrates of episodic memory suppression in posthypnotic amnesia
Yeshurun_2008_Behav.Neurosci_122_1031 Working memory across nostrils
Birner-Gruenberger_2008_Proteomics_8_3645 Lipolytic and esterolytic activity-based profiling of murine liver
Stoger_2008_Pharmacogenomics_9_1851 Epigenetics and obesity
Wise_2008_Neuropharmacol_54_181 Evaluation of fatty acid amides in the carrageenan-induced paw edema model
Yang_2008_Biochim.Biophys.Acta_1781_123 Lipidomic analysis reveals differential defense responses of Taxus cuspidata cells to two elicitors, methyl jasmonate and cerium (Ce4+)
Huang_2008_J.Med.Chem_51_6293 Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding
Lee_2008_Arch.Neurol_65_1518 Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci
Pitt_2008_J.Neurosci_28_11454 High intracellular chloride slows the decay of glycinergic currents
Tort_2008_Proc.Natl.Acad.Sci.U.S.A_105_20517 Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task
Chen_2008_Toxicology_249_194 Toxicological analysis of low-nicotine and nicotine-free cigarettes
Cucchiaro_2008_Anesthesiology_109_512 Analgesic effects of Sazetidine-A, a new nicotinic cholinergic drug
Gao_2008_J.Med.Chem_51_4751 Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2 .1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging properties
Moaddel_2008_Anal.Chem_80_48 Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type
Butini_2008_J.Med.Chem_51_3154 Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors
Butini_2008_Bioorg.Med.Chem.Lett_18_5213 Tacrine based human cholinesterase inhibitors: synthesis of peptidic-tethered derivatives and their effect on potency and selectivity
Akuffo_2008_Biomarkers_13_618 The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone
Berend_2008_Arh.Hig.Rada.Toksikol_59_205 [Determination of total polyphenol content in food with the flow-injection method]
Gyengesi_2008_Brain.Res.Bull_75_570 The effect of prefrontal stimulation on the firing of basal forebrain neurons in urethane anesthetized rat
Zaborszky_2008_Neuroimage_42_1127 Stereotaxic probabilistic maps of the magnocellular cell groups in human basal forebrain
Nirthanan_2008_J.Biol.Chem_283_22051 Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector
Palea_2008_J.Cataract.Refract.Surg_34_489 Comparative effect of alfuzosin and tamsulosin on the contractile response of isolated rabbit prostatic and iris dilator smooth muscles: possible model for intraoperative floppy-iris syndrome
Pedrosa_2008_Sensors.(Basel)_8_4600 Determination of Parathion and Carbaryl Pesticides in Water and Food Samples Using a Self Assembled Monolayer \/Acetylcholinesterase Electrochemical Biosensor
Pohanka_2008_Sensors.(Basel)_8_5229 Diagnosis of Intoxication by the Organophosphate VX: Comparison Between an Electrochemical Sensor and Ellman s Photometric Method
Pohanka_2008_Sensors.(Basel)_8_5303 Amperometric Biosensors for Real Time Assays of Organophosphates
Johansson_2008_PLoS.Genet_4_e1000278 An ancient duplication of exon 5 in the Snap25 gene is required for complex neuronal development\/function
Wada_2008_Microbes.Environ_23_331 Effect of three organophosphorous nematicides on non-target nematodes and soil microbial community
Assumpcao_2008_Insect.Biochem.Mol.Biol_38_213 An insight into the sialome of the blood-sucking bug Triatoma infestans, a vector of Chagas' disease
Francischetti_2008_Insect.Biochem.Mol.Biol_38_1 An insight into the sialome of the soft tick, Ornithodorus parkeri
Francischetti_2008_J.Proteomics_71_493 An insight into the salivary transcriptome and proteome of the soft tick and vector of epizootic bovine abortion, Ornithodoros coriaceus
Kahler_2008_Am.J.Med.Genet.B.Neuropsychiatr.Genet_147B_1089 Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Xu_2008_J.Chromatogr.A_1205_158 Ion-pair liquid-liquid-liquid microextraction of nerve agent degradation products followed by capillary electrophoresis with contactless conductivity detection
Menuz_2008_J.Neurosci_28_8740 TARP redundancy is critical for maintaining AMPA receptor function
Farfara_2008_J.Cell.Mol.Med_12_762 Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease
Satin_2008_Stem.Cells_26_1961 Calcium handling in human embryonic stem cell-derived cardiomyocytes
Huang_2008_BMC.Biotechnol_8_50 Substantially improved pharmacokinetics of recombinant human butyrylcholinesterase by fusion to human serum albumin
Reeves_2008_Protein.Eng.Des.Sel_21_405 Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities
Yeung_2008_J.Anal.Toxicol_32_86 A gas chromatographic-mass spectrometric approach to examining stereoselective interaction of human plasma proteins with soman
Jain_2008_Toxicol.Appl.Pharmacol_230_247 Microsomal epoxide hydrolase (EPHX1), slow (exon 3, 113His) and fast (exon 4, 139Arg) alleles confer susceptibility to squamous cell esophageal cancer
Brandt_2008_Peptides_29_1472 Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein
Dubois_2008_Front.Biosci_13_3558 Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes
Lambeir_2008_Biochem.Pharmacol_76_1637 DPP4 inhibitors for diabetes--what next?
Lu_2008_J.Lipid.Res_49_2582 Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations
Wei_2008_Hum.Mol.Genet_17_469 ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones
Badeloe_2008_Br.J.Dermatol_158_1378 Chanarin-Dorfman syndrome caused by a novel splice site mutation in ABHD5
Gaeta_2008_Skeletal.Radiol_37_1053 Opposed-phase MR imaging of lipid storage myopathy in a case of Chanarin-Dorfman disease
Kiss_2008_J.Inherit.Metab.Dis_31 Suppl 2_S205 A Brazilian galactosialidosis patient given renal transplantation: a case report
Torisu_2008_Cancer.Sci_99_1139 Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin\/TCF
Gardner_2008_J.Biol.Chem_283_17099 Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein
Sutton_2008_Hum.Mol.Genet_17_1318 Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets
Cristillo_2008_Biochem.Biophys.Res.Commun_370_22 HIV-1 Env vaccine comprised of electroporated DNA and protein co-administered with Talabostat
Hejnol_2008_Nature_456_382 Acoel development indicates the independent evolution of the bilaterian mouth and anus
Hejnol_2008_Philos.Trans.R.Soc.Lond.B.Biol.Sci_363_1493 Acoel development supports a simple planula-like urbilaterian
Semmler_2008_Front.Zool_5_14 Myogenesis in the basal bilaterian Symsagittifera roscoffensis (Acoela)
Abdel-Fattah_2008_Microbiol.Res_163_13 Identification and over-expression of a thermostable lipase from Geobacillus thermoleovorans Toshki in Escherichia coli
Creeley_2008_Neurobiol.Aging_29_153 Donepezil markedly potentiates memantine neurotoxicity in the adult rat brain
Darreh-Shori_2008_Neurobiol.Aging_29_168 Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine
Peltzer_2008_Ecotoxicol.Environ.Saf_70_185 Effects of agricultural pond eutrophication on survival and health status of Scinax nasicus tadpoles
Rodriguez-Fuentes_2008_Ecotoxicol.Environ.Saf_69_466 Characterization of muscle cholinesterases from two demersal flatfish collected near a municipal wastewater outfall in Southern California
Zhang_2008_Cell.Mol.Neurobiol_28_173 Non-cholinergic effects of huperzine A: beyond inhibition of acetylcholinesterase
Aalten_2008_Dement.Geriatr.Cogn.Disord_25_1 Consistency of neuropsychiatric syndromes across dementias: results from the European Alzheimer Disease Consortium. Part II
Abegaz_2008_Pharmacol.Res_57_87 Response to the effect of aspartame on the acetylcholinesterase activity in hippocampal homogenates of suckling rats by Simintzi et al
Acharya_2008_Toxicol.In.Vitro_22_525 In vitro reactivation of sarin inhibited electric eel acetylcholinesterase by bis-pyridinium oximes bearing methoxy ether linkages
Aloulou_2008_Aliment.Pharmacol.Ther_27_283 In vitro comparative study of three pancreatic enzyme preparations: dissolution profiles, active enzyme release and acid stability
Anderson_2008_J.Cell.Physiol_215_82 Morphoregulation by acetylcholinesterase in fibroblasts and astrocytes
Andreani_2008_Eur.J.Med.Chem_43_657 Chemiluminescent high-throughput microassay applied to imidazo[2,1-b]thiazole derivatives as potential acetylcholinesterase and butyrylcholinesterase inhibitors
Azuma_2008_J.Clin.Endocrinol.Metab_93_459 Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes
Baldassarre_2008_Transgenic.Res_17_73 Lactation performance of transgenic goats expressing recombinant human butyryl-cholinesterase in the milk
Batulevicius_2008_Auton.Neurosci_138_64 Topography of the porcine epicardiac nerve plexus as revealed by histochemistry for acetylcholinesterase
Bernacer_2008_J.Neural.Transm.(Vienna)_115_67 Chemical architecture of the posterior striatum in the human brain
Bruandet_2008_Dement.Geriatr.Cogn.Disord_25_74 Cognitive decline and survival in Alzheimer's disease according to education level
Buchanan_2008_Am.J.Psychiatry_165_82 Galantamine for the treatment of cognitive impairments in people with schizophrenia
Busek_2008_Physiol.Res_57_443 Modulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines
Busek_2008_Front.Biosci_13_2319 Dipeptidyl peptidase-IV enzymatic activity bearing molecules in human brain tumors--good or evil?
Byrd_2008_Hypertension_51_141 Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema
Cambon_2008_Biotechnol.Lett_30_769 Characterization of typo-, regio-, and stereo-selectivities of babaco latex lipase in aqueous and organic media
Campbell_2008_Front.Biosci_13_1795 CD26 inhibition and hematopoiesis: a novel approach to enhance transplantation
Chang_2008_Neurobiol.Learn.Mem_89_167 Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome
Chang_2008_Bioresour.Technol_99_2800 Studies of optimum conditions for covalent immobilization of Candida rugosa lipase on poly(gamma-glutamic acid) by RSM
Chen_2008_Clin.Neurophysiol_119_504 The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee
Chiu_2008_Neuropharmacol_54_68 Input-specific plasticity at excitatory synapses mediated by endocannabinoids in the dentate gyrus
Christin_2008_Neurochem.Res_33_919 Effects of repeated low-dose soman exposure on monoamine levels in different brain structures in mice
Clauss_2008_Plant.J_53_802 Role of a GDSL lipase-like protein as sinapine esterase in Brassicaceae
Connelly_2008_Int.J.Geriatr.Psychiatry_23_155 A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease
Contestabile_2008_Neurochem.Res_33_318 The place of choline acetyltransferase activity measurement in the cholinergic hypothesis of neurodegenerative diseases
Correa_2008_Biomed.Pharmacother_62_317 Oxidative stress and erythrocyte acetylcholinesterase (AChE) in hypertensive and ischemic patients of both acute and chronic stages
Costa_2008_Bioprocess.Biosyst.Eng_31_323 Comparing the effect of immobilization methods on the activity of lipase biocatalysts in ester hydrolysis
Couillard_2008_Arch.Environ.Contam.Toxicol_54_283 Effects of diazinon on mummichog (Fundulus heteroclitus) larvae produced from eggs differentially treated with PCB126
Curtin_2008_J.Cell.Biochem_103_1524 Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines
da Fonseca_2008_Ecotoxicol.Environ.Saf_69_416 The 2,4-D herbicide effects on acetylcholinesterase activity and metabolic parameters of piava freshwater fish (Leporinus obtusidens)
Deacon_2008_Front.Biosci_13_1780 DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes
Debord_2008_Anal.Biochem_373_247 Microcalorimetric study of the inhibition of butyrylcholinesterase by carbamates
Dewan_2008_Clin.Toxicol.(Phila)_46_85 Mass ethion poisoning with high mortality
Ebata_2008_Macromol.Biosci_8_38 Lipase-catalyzed synthesis and properties of poly[(12-hydroxydodecanoate)-co-(12-hydroxystearate)] directed towards novel green and sustainable elastomers
Exley_2008_Neuropsychopharmacology_33_2158 Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens
Figiel_2008_Curr.Med.Res.Opin_24_157 A systematic review of the effectiveness of rivastigmine for the treatment of behavioral disturbances in dementia and other neurological disorders
Fock_2008_Exp.Hematol_36_78 NF-E2-mediated enhancement of megakaryocytic differentiation and platelet production in vitro and in vivo
Foulkes_2008_Stat.Med_27_2784 Mixed modeling and multiple imputation for unobservable genotype clusters
Freeling_2008_Exp.Physiol_93_75 Neostigmine and pilocarpine attenuated tumour necrosis factor alpha expression and cardiac hypertrophy in the heart with pressure overload
Funk_2008_Eur.J.Anaesthesiol_25_37 Physostigmine and anaesthesia emergence delirium in preschool children: a randomized blinded trial
Gagnaire_2008_Chemosphere_71_553 Cholinesterase activities as potential biomarkers: characterization in two freshwater snails, Potamopyrgus antipodarum (Mollusca, Hydrobiidae, Smith 1889) and Valvata piscinalis (Mollusca, Valvatidae, Muller 1774)
Gonzalez-Gronow_2008_Front.Biosci_13_1610 Dipeptidyl peptidase IV (DPP IV\/CD26) is a cell-surface plasminogen receptor
Gorbi_2008_Mar.Environ.Res_65_34 An ecotoxicological protocol with caged mussels, Mytilus galloprovincialis, for monitoring the impact of an offshore platform in the Adriatic Sea
Gorfe_2008_Biophys.J_94_1144 Dynamics of the acetylcholinesterase tetramer
Gottmann_2008_J.Neurosci.Res_86_223 Transsynaptic modulation of the synaptic vesicle cycle by cell-adhesion molecules
Grasing_2008_Psychopharmacology.(Berl)_196_133 Dose-related effects of the acetylcholinesterase inhibitor tacrine on cocaine and food self-administration in rats
Grigoryan_2008_Chem.Biol.Interact_171_108 alpha,beta-Dehydrophenylalanine choline esters, a new class of reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase
Guncheva_2008_Biotechnol.Lett_30_509 High-yield synthesis of wax esters catalysed by modified Candida rugosa lipase
Hannam_2008_Environ.Pollut_152_342 Characterisation of esterases as potential biomarkers of pesticide exposure in the lugworm Arenicola marina (Annelida: Polychaeta)
Hartmann_2008_Neurochem.Int_52_972 Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice
Hashimotodani_2008_Neuropharmacol_54_58 Pharmacological evidence for the involvement of diacylglycerol lipase in depolarization-induced endocanabinoid release
Havre_2008_Front.Biosci_13_1634 The role of CD26\/dipeptidyl peptidase IV in cancer
Hong_2008_Planta_227_539 Function of a novel GDSL-type pepper lipase gene, CaGLIP1, in disease susceptibility and abiotic stress tolerance
Itou_2008_J.Gastroenterol.Hepatol_23_244 Altered expression of glucagon-like peptide-1 and dipeptidyl peptidase IV in patients with HCV-related glucose intolerance
Jackson_2008_Clin.Exp.Pharmacol.Physiol_35_29 Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure
Jemec_2008_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_147_61 Biochemical biomarkers in chronically metal-stressed daphnids
Jin-Clark_2008_Arch.Environ.Contam.Toxicol_54_645 Effect of alachlor and metolachlor on toxicity of chlorpyrifos and major detoxification enzymes in the aquatic midge, Chironomus tentans (Diptera: Chironomidae)
Jing_2008_J.Neurochem_104_409 GSK3beta mediates the induced expression of synaptic acetylcholinesterase during apoptosis
Johnell_2008_Dement.Geriatr.Cogn.Disord_25_54 Education and use of dementia drugs: a register-based study of over 600,000 older people
Jung_2008_Biotechnol.Lett_30_717 Improving the expression yield of Candida antarctica lipase B in Escherichia coli by mutagenesis
Kang_2008_J.Biol.Chem_283_2323 Induction of GABAergic postsynaptic differentiation by alpha-neurexins
Keefe_2008_Neuropsychopharmacology_33_1217 Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: significant placebo\/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial
Kempka_2008_Bioprocess.Biosyst.Eng_31_119 Response surface method to optimize the production and characterization of lipase from Penicillium verrucosum in solid-state fermentation
Kim_2008_Diabetes_57_64 Acute diabetes moderates trafficking of cardiac lipoprotein lipase through p38 mitogen-activated protein kinase-dependent actin cytoskeleton organization
Knol_2008_Eur.J.Nucl.Med.Mol.Imaging_35_598 No significant effects of single intravenous, single oral and subchronic oral administration of acetylcholinesterase inhibitors on striatal [123I]FP-CIT binding in rats
Koch_2008_Biotechnol.Bioeng_99_1028 Enzymatic enantioselective C-C-bond formation in microreactors
Koda_2008_Psychopharmacology.(Berl)_196_293 Galantamine and donepezil differently affect isolation rearing-induced deficits of prepulse inhibition in mice
Kopecka_2008_Ecotoxicol.Environ.Saf_70_379 Temporal and spatial variations of selected biomarker activities in flounder (Platichthys flesus) collected in the Baltic proper
Kuang_2008_Pharmacol.Biochem.Behav_88_213 Postischemic administration of Z-Ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats
Kuhad_2008_Exp.Brain.Res_185_411 Effect of sesamol on diabetes-associated cognitive decline in rats
Kumari_2008_Bioprocess.Biosyst.Eng_31_291 Comparative study of thermostability and ester synthesis ability of free and immobilized lipases on cross linked silica gel
Lee_2008_Clin.Chim.Acta_387_172 Compound heterozygosity of novel missense mutations (Ser45 --> Gly, Cys278 --> Arg) in the lipoprotein lipase gene in a newborn Korean infant
Lemstra_2008_Dement.Geriatr.Cogn.Disord_25_60 Identification of responders to rivastigmine: a prospective cohort study
Levi_2008_Pharmacol.Biochem.Behav_88_438 Discrimination and avoidance learning in adult mice following developmental exposure to diisopropylfluorophosphate
Leyhe_2008_Eur.Arch.Psychiatry.Clin.Neurosci_258_124 Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease
Li_2008_Chemosphere_70_1796 Effects of nonionic and ionic surfactants on survival, oxidative stress, and cholinesterase activity of planarian
Liu_2008_Endocrinology_149_711 Estrogen-enhanced gene expression of lipoprotein lipase in heart is antagonized by progesterone
Liu_2008_Biotechnol.Lett_30_497 Lipase-catalyzed selective synthesis of monolauroyl maltose using continuous stirred tank reactor
Liu_2008_Ultrason.Sonochem_15_402 The effect of ultrasound on lipase-catalyzed hydrolysis of soy oil in solvent-free system
Llorca_2008_Acta.Neurol.Scand_117_1 Meta-analysis of genetic variability in the beta-amyloid production, aggregation and degradation metabolic pathways and the risk of Alzheimer's disease
Louh_2008_Phytochemistry_69_1013 Polyanxanthone A, B and C, three xanthones from the wood trunk of Garcinia polyantha Oliv
Maeck_2008_Int.J.Geriatr.Psychiatry_23_415 Primary care physicians' attitudes related to cognition enhancers in early dementia: a representative eight-year follow-up study in Lower Saxony, Germany
Mahmoud_2008_J.Reprod.Immunol_77_186 Butyrylcholinesterase activity and lymphocyte subpopulations in peripheral blood of Kuwaiti women experiencing recurrent spontaneous abortion
Maitra_2008_Ecotoxicol.Environ.Saf_71_236 Testicular functions and serum titers of LH and testosterone in methyl parathion-fed roseringed parakeets
Massa_2008_Ecotoxicol.Environ.Saf_71_230 Role of acetylcholinesterase and glutathione S-transferase following exposure to nicosulfuron and diazinon in Helicoverpa zea
McGuinness_2008_Front.Biosci_13_2435 Dipeptidyl peptidase IV (DPPIV), a candidate tumor suppressor gene in melanomas is silenced by promoter methylation
McIntosh_2008_Front.Biosci_13_1753 Dipeptidyl peptidase IV inhibitors and diabetes therapy
Michalski_2008_Int.J.Cancer_122_742 Cannabinoids in pancreatic cancer: correlation with survival and pain
Miyashita_2008_Br.J.Nutr_99_1076 Moderate exercise reduces serum triacylglycerol concentrations but does not affect pre-heparin lipoprotein lipase concentrations after a moderate-fat meal in young men
Mwanza_2008_Neurotoxicol_29_87 Depression of the photic after discharge of flash evoked potentials by physostigmine, carbaryl and propoxur, and the relationship to inhibition of brain cholinesterase
Ng_2008_J.Affect.Disord_107_307 A case series on the hypothesized connection between dementia and bipolar spectrum disorders: bipolar type VI?
Nordblad_2008_J.Biotechnol_133_127 Effects of acid concentration and solvent choice on enzymatic acrylation by Candida antarctica lipase B
Nordblad_2008_Biotechnol.Bioeng_99_1518 Efficient enzymatic acrylation through transesterification at controlled water activity
Ohnuma_2008_Front.Biosci_13_2299 Role of CD26\/dipeptidyl peptidase IV in human T cell activation and function
Okamura_2008_Br.J.Clin.Pharmacol_65_472 In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease
Okuno_2008_Toxicol.Appl.Pharmacol_227_8 Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS\/MS
Park_2008_Bioresour.Technol_99_3130 Lipase-catalyzed biodiesel production from waste activated bleaching earth as raw material in a pilot plant
Pathiratne_2008_Arch.Environ.Contam.Toxicol_54_309 Effects of biological and technical factors on brain and muscle cholinesterases in Nile tilapia, Oreochromis niloticus: implications for biomonitoring neurotoxic contaminations
Petraglio_2008_Proteins_70_779 The role of Li+, Na+, and K+ in the ligand binding inside the human acetylcholinesterase gorge
Piazzi_2008_Bioorg.Med.Chem.Lett_18_423 Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds
Punga_2008_Muscle.Nerve_37_300 Electrophysiological signs and the prevalence of adverse effects of acetylcholinesterase inhibitors in patients with myasthenia gravis
Rajan_2008_Bioprocess.Biosyst.Eng_31_87 Studies on crystallization and cross-linking of lipase for biocatalysis
Rawlings_2008_Biochimie_90_243 The MEROPS batch BLAST: a tool to detect peptidases and their non-peptidase homologues in a genome
Rawlings_2008_Nucleic.Acids.Res_36_D320 MEROPS: the peptidase database
Reinhold_2008_Front.Biosci_13_2356 DP IV\/CD26, APN\/CD13 and related enzymes as regulators of T cell immunity: implications for experimental encephalomyelitis and multiple sclerosis
Renwick_2008_Food.Chem.Toxicol_46_1206 Re: The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study
Reshma_2008_Bioresour.Technol_99_5011 Lipase catalyzed interesterification of palm stearin and rice bran oil blends for preparation of zero trans shortening with bioactive phytochemicals
Rivellese_2008_Clin.Nutr_27_133 Effects of monounsaturated vs. saturated fat on postprandial lipemia and adipose tissue lipases in type 2 diabetes
Rockwood_2008_Int.J.Geriatr.Psychiatry_23_207 Patterns of decline and evidence of subgroups in patients with Alzheimer's disease taking galantamine for up to 48 months
Ruchi_2008_Bioresour.Technol_99_4796 Lipase from solvent tolerant Pseudomonas aeruginosa strain: production optimization by response surface methodology and application
Saerens_2008_Biotechnol.Lett_30_311 Release of short chain fatty acids from cream lipids by commercial lipases and esterases
Salloway_2008_Int.Psychogeriatr_20_40 Key lessons learned from short-term treatment trials of cholinesterase inhibitors for amnestic MCI
Santos_2008_Colloids.Surf.B.Biointerfaces_61_229 Covalent attachment of Candida rugosa lipase on chemically modified hybrid matrix of polysiloxane-polyvinyl alcohol with different activating compounds
Schade_2008_J.Histochem.Cytochem_56_147 Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8\/9, and DP10 in allergic responses of the lung in rats
Scheuhammer_2008_Ecotoxicology_17_93 Relationships among mercury, selenium, and neurochemical parameters in common loons (Gavia immer) and bald eagles (Haliaeetus leucocephalus)
Senthil_2008_Ecotoxicol.Environ.Saf_70_244 Effect of azadirachtin on acetylcholinesterase (AChE) activity and histology of the brown planthopper Nilaparvata lugens (Stal)
Shankle_2008_Neurol.Res_30_313 Omentum transposition surgery for patients with Alzheimer's disease: a case series
Shen_2008_Med.Hypotheses_70_43 Rationale for diagnosing deficiency of ChEs and for applying exogenous HuChEs to the treatment of diseases
Smith_2008_Pharmacogenomics.J_8_228 Allelic variation in ApoC3, ApoA5 and LPL genes and first and second generation antipsychotic effects on serum lipids in patients with schizophrenia
Stasiewicz_2008_Ecotoxicol.Environ.Saf_71_157 Assessing toxicity and biodegradation of novel, environmentally benign ionic liquids (1-alkoxymethyl-3-hydroxypyridinium chloride, saccharinate and acesulfamates) on cellular and molecular level
Strode_2008_Insect.Biochem.Mol.Biol_38_113 Genomic analysis of detoxification genes in the mosquito Aedes aegypti
Sultana_2008_Nat.Prod.Res_22_37 A new fatty ester and a new triterpene from Skimmia laureola
Swarts_2008_Biotechnol.Bioeng_99_855 Comparison of two-phase lipase-catalyzed esterification on micro and bench scale
Tang_2008_J.Lipid.Res_49_369 Protective effect of an endothelial lipase gene variant on coronary artery disease in a Chinese population
Teng_2008_Bioresour.Technol_99_3900 Culture condition improvement for whole-cell lipase production in submerged fermentation by Rhizopus chinensis using statistical method
Terriere_2008_Neurochem.Res_33_643 alpha4beta2-nicotinic receptor binding with 5-IA in Alzheimer's disease: methods of scan analysis
Thielitz_2008_Front.Biosci_13_2364 The ectopeptidases dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN) and their related enzymes as possible targets in the treatment of skin diseases
Thielitz_2008_J.Invest.Dermatol_128_855 Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts
Tobin_2008_Eur.J.Appl.Physiol_102_361 The effect of exercise on postprandial lipidemia in type 2 diabetic patients
Tsakiris_2008_Br.J.Sports.Med_42_367 Effect of L-carnitine administration on the modulated rat brain protein concentration, acetylcholinesterase, Na+K+-ATPase and Mg2+-ATPase activities induced by forced swimming
Tyler_2008_Environ.Pollut_152_217 Examining the joint toxicity of chlorpyrifos and atrazine in the aquatic species: Lepomis macrochirus, Pimephales promelas and Chironomus tentans
Vaidya_2008_Bioresour.Technol_99_3623 Immobilization of Candida rugosa lipase on poly(allyl glycidyl ether-co-ethylene glycol dimethacrylate) macroporous polymer particles
Vaidya_2008_Colloids.Surf.B.Biointerfaces_61_101 Use of insoluble yeast beta-glucan as a support for immobilization of Candida rugosa lipase
Vaisi-Raygani_2008_Scand.J.Clin.Lab.Invest_68_123 Butyrylcholinesterase K variants increase the risk of coronary artery disease in the population of western Iran
Van Dam_2008_Psychopharmacology.(Berl)_197_37 Cognitive evaluation of disease-modifying efficacy of donepezil in the APP23 mouse model for Alzheimer's disease
Voss_2008_Nervenarzt_79_47 [Therapy of cognitive deficits in schizophrenia with acetylcholinesterase inhibitors. A systematic overview]
Wang_2008_Front.Biosci_13_3168 Fibroblast activation protein and chronic liver disease
Wu_2008_Clin.Toxicol.(Phila)_46_110 State-wide hospital clinical laboratory plan for measuring cholinesterase activity for individuals suspected of exposure to nerve agent chemical weapons
Yamamoto_2008_Planta_227_809 Characterization of trimeric acetylcholinesterase from a legume plant, Macroptilium atropurpureum Urb
Yan_2008_Am.J.Obstet.Gynecol_198_229 e1 The effect of esterases on 17alpha-hydroxyprogesterone caproate
Yang_2008_Curr.Microbiol_56_194 Cloning and expression of lipP, a gene encoding a cold-adapted lipase from Moritella sp.2-5-10-1
Zhang_2008_Circ.Res_102_250 Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet
Zimmermann_2008_J.Neurochem_104_221 Selective enhancement of the activity of C-terminally truncated, but not intact, acetylcholinesterase
Aaboe_2008_Diabetes.Obes.Metab_10_994 GLP-1: physiological effects and potential therapeutic applications
Aardema_2008_Neth.J.Med_66_149 Organophosphorus pesticide poisoning: cases and developments
Abel_2008_Vertex_19 Suppl_39 [Treatment of Alzheimer's Disease cognitive symptoms]
Abou-Donia_2008_J.Toxicol.Environ.Health.A_71_119 Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure
Acevedo_2008_J.Biotechnol_133_277 Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique
Adam_2008_Neurotherapeutics_5_181 Symptomatic treatment of Huntington disease
Adkins_2008_J.Phys.Chem.B_112_4760 Stable colloidal dispersions of a lipase-perfluoropolyether complex in liquid and supercritical carbon dioxide
Aird_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_222 Snake venom dipeptidyl peptidase IV: taxonomic distribution and quantitative variation
Alonzi_2008_Expert.Rev.Proteomics_5_91 Elucidation of lipoprotein particles structure by proteomic analysis
Ames_2008_Int.Psychogeriatr_20_259 For debate: is the evidence for the efficacy of cholinesterase inhibitors in the symptomatic treatment of Alzheimer's disease convincing or not?
Ammazzalorso_2008_Chirality_20_115 Candida rugosa lipase-catalysed kinetic resolution of 2-substituted-aryloxyacetic esters with dimethylsulfoxide and isopropanol as additives
Arastu-Kapur_2008_Nat.Chem.Biol_4_203 Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum
Bacchetta_2008_Sci.Total.Environ_392_110 Axial-skeletal defects caused by Carbaryl in Xenopus laevis embryos
Badellino_2008_Circulation_117_678 Endothelial lipase is increased in vivo by inflammation in humans
Bagautdinov_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_351 Structure of putative CutA1 from Homo sapiens determined at 2.05 A resolution
Balali-Mood_2008_Arch.Iran.Med_11_65 Neurotoxic disorders of organophosphorus compounds and their managements
Barthel_2008_J.Med.Chem_51_298 Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug
Baruah_2008_Br.J.Anaesth_100_420 Effects of acetylcholinesterase inhibitor therapy for Alzheimer's disease on neuromuscular block
Bawaskar_2008_Lancet_371_696 Snakebite, cocktails, and a girl with a stomach ache
Bembenek_2008_Bioorg.Med.Chem_16_2968 Lead identification of acetylcholinesterase inhibitors-histamine H3 receptor antagonists from molecular modeling
Bentley_2008_Brain_131_409 Cholinesterase inhibition modulates visual and attentional brain responses in Alzheimer's disease and health
Berk_2008_Obesity.(Silver.Spring)_16_199 Higher post-absorptive skeletal muscle LPL activity in African American vs. non-Hispanic White pre-menopausal women
Berkov_2008_Phytochem.Anal_19_285 Analysis of galanthamine-type alkaloids by capillary gas chromatography-mass spectrometry in plants
Berkov_2008_Bioorg.Med.Chem.Lett_18_2263 N-Alkylated galanthamine derivatives: Potent acetylcholinesterase inhibitors from Leucojum aestivum
Bermudez-Silva_2008_Diabetologia_51_476 Presence of functional cannabinoid receptors in human endocrine pancreas
Berndt_2008_Exp.Clin.Endocrinol.Diabetes_116_203 Adipose triglyceride lipase gene expression in human visceral obesity
Berny_2008_J.Wildl.Dis_44_417 Acute poisoning of Red Kites (Milvus milvus) in France: data from the Sagir network
Blazer_2008_Proc.Natl.Acad.Sci.U.S.A_105_E20 Acetylcholinesterase inhibition and Gulf War illnesses: conclusions are not supported by independent reviews of the same evidence
Bosak_2008_Arch.Biochem.Biophys_471_72 Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol
Bovet_2008_Anal.Biochem_373_380 Determination of active enzyme concentration using activity-based probes and direct mass spectrometric readout
Brigida_2008_Appl.Biochem.Biotechnol_146_173 Immobilization of Candida antarctica lipase B by adsorption to green coconut fiber
Brown_2008_Can.Commun.Dis.Rep_34_20 Absence of prolyliminopeptidase-negative Neisseria gonorroeae strains in Ontario, Canada
Bui_2008_Chem.Biol.Interact_175_303 Intrinsic conformational flexibility of acetylcholinesterase
Burger_2008_J.Chem.Ecol_34_659 Chemical characterization of territorial marking fluid of male Bengal tiger, Panthera tigris
Burmeister_2008_Biosens.Bioelectron_23_1382 Ceramic-based multisite microelectrode arrays for simultaneous measures of choline and acetylcholine in CNS
Byers_2008_J.Anal.Toxicol_32_57 Gas chromatography-tandem mass spectrometry analysis of red blood cells from Gottingen minipig following whole-body vapor exposure to VX
Cacabelos_2008_Eur.Arch.Psychiatry.Clin.Neurosci_258 Suppl 1_28 Pharmacogenomics and therapeutic prospects in dementia
Caliskan_2008_Anesth.Analg_106_959 A prospective randomized double-blind study to determine the effect of thoracic epidural neostigmine on postoperative ileus after abdominal aortic surgery
Camp_2008_J.Neurosci_28_2459 Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhancesome in the first intron
Casas_2008_J.Eukaryot.Microbiol_55_34 Continuous culture of Perkinsus mediterraneus, a parasite of the European flat oyster Ostrea edulis, and characterization of its morphology, propagation, and extracellular proteins in vitro
Catano_2008_Arch.Environ.Contam.Toxicol_55_153 Plasma cholinesterase levels and health symptoms in peruvian farm workers exposed to organophosphate pesticides
Chae_2008_Bioconjug.Chem_19_334 Preparation, characterization, and application of biotinylated and biotin-PEGylated glucagon-like peptide-1 analogues for enhanced oral delivery
Cheetham_2008_Equine.Vet.J_40_70 Neuroanatomy of the equine dorsal cricoarytenoid muscle: surgical implications
Cheshire_2008_Drug.Saf_31_109 Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management
Choi_2008_Dement.Geriatr.Cogn.Disord_25_445 Effect of ApoE genotype on response to donepezil in patients with Alzheimer's disease
Chougule_2008_J.Cancer.Res.Ther_4_21 Prognostic and diagnostic value of serum pseudocholinesterase, serum aspartate transaminase, and serum alinine transaminase in malignancies treated by radiotherapy
Christodoulou_2008_CNS.Drugs_22_87 Treatment of cognitive impairment in multiple sclerosis: is the use of acetylcholinesterase inhibitors a viable option?
Coelho_2008_Expert.Opin.Pharmacother_9_523 Treatment options for non-motor symptoms in late-stage Parkinson's disease
Cui_2008_Planta.Med_74_377 Effect of glabridin from Glycyrrhiza glabra on learning and memory in mice
Cunha_2008_Appl.Biochem.Biotechnol_146_49 Immobilization of Yarrowia lipolytica lipase--a comparison of stability of physical adsorption and covalent attachment techniques
Dabisch_2008_Inhal.Toxicol_20_149 Biomarkers of low-level exposure to soman vapor: comparison of fluoride regeneration to acetylcholinesterase inhibition
Das_2008_Biochimie_90_820 Improved activity of enzymes in mixed cationic reverse micelles with imidazolium-based surfactants
Desrosiers_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_200 Ontogenesis of catabolic and energy metabolism capacities during the embryonic development of spotted wolffish (Anarhichas minor)
Detel_2008_Exp.Aging.Res_34_49 The influence of age on intestinal dipeptidyl peptidase IV (DPP IV\/CD26), disaccharidases, and alkaline phosphatase enzyme activity in C57BL\/6 mice
Di Giovanni_2008_Eur.J.Pharm.Sci_33_109 In vitro screening assays to identify natural or synthetic acetylcholinesterase inhibitors: thin layer chromatography versus microplate methods
Ding_2008_Sheng.Wu.Gong.Cheng.Xue.Bao_24_239 [Molecular cloning and characterization of an acetylcholinesterase gene Dd-ace-2 from sweet potato stem nematode Ditylenchus destructor]
Donaldson_2008_Age.Ageing_37_237 Acetylcholinesterase inhibitors and cardiovascular disease
Du_2008_Talanta_74_766 Electrochemical pesticide sensitivity test using acetylcholinesterase biosensor based on colloidal gold nanoparticle modified sol-gel interface
Du_2008_Talanta_74_1337 In situ electrodeposited nanoparticles for facilitating electron transfer across self-assembled monolayers in biosensor design
Dutra_2008_Appl.Biochem.Biotechnol_147_63 Lipase production in solid-state fermentation monitoring biomass growth of aspergillus niger using digital image processing
Duysen_2008_Chem.Biol.Interact_175_119 Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase
Eberl_2008_J.Biotechnol_135_45 Enzymatic hydrolysis of PTT polymers and oligomers
Ela_2008_Clin.Toxicol.(Phila)_46_141 Influence of atropine therapy on fenthion-induced pancreatitis
Elliott_2008_Environ.Toxicol.Chem_27_452 Fonofos poisons raptors and waterfowl several months after granular application
Evans_2008_J.Anal.Toxicol_32_78 Quantification of sarin and cyclosarin metabolites isopropyl methylphosphonic acid and cyclohexyl methylphosphonic acid in minipig plasma using isotope-dilution and liquid chromatography- time-of-flight mass spectrometry
Ezoulin_2008_Neurotoxicol_29_270 Antioxidative properties of galantamine on neuronal damage induced by hydrogen peroxide in SK-N-SH cells
Fanciulli_2008_Exp.Clin.Endocrinol.Diabetes_116_148 An inhibition of the hypothalamic somatostatinergic tone is not the cause of the enhanced growth hormone response to growth hormone-releasing hormone in patients with liver cirrhosis
Farlow_2008_Dement.Geriatr.Cogn.Disord_25_408 Treatment options in Alzheimer's disease: maximizing benefit, managing expectations
Fatima_2008_Protein.Pept.Lett_15_346 Characterization of fluoroalcohols-induced intermediates of Mucor miehei lipase at low pH
Filippatos_2008_Drug.Saf_31_53 Orlistat-associated adverse effects and drug interactions: a critical review
Fodale_2008_Crit.Care.Med_36_622 Cholinesterase inhibitors improve survival in experimental sepsis: a new way to activate the cholinergic anti-inflammatory pathway
Frederiksen_2008_Scand.J.Urol.Nephrol_42_205 Nerve distribution in rat urinary bladder after incorporation of acellular matrix graft or subtotal cystectomy
Fregolente_2008_Appl.Biochem.Biotechnol_146_165 Monoglycerides and diglycerides synthesis in a solvent-free system by lipase-catalyzed glycerolysis
Furne_2008_Comp.Biochem.Physiol.A.Mol.Integr.Physiol_149_420 Effect of starvation and refeeding on digestive enzyme activities in sturgeon (Acipenser naccarii) and trout (Oncorhynchus mykiss)
Galvin_2008_Alzheimer.Dis.Assoc.Disord_22_30 Effects of galantamine on measures of attention: results from 2 clinical trials in Alzheimer disease patients with comparisons to donepezil
Garber_2008_Expert.Opin.Investig.Drugs_17_105 Update: vildagliptin for the treatment of Type 2 diabetes
Garcia-Soria_2008_Diabetes.Obes.Metab_10_293 The dipeptidyl peptidase-4 inhibitor PHX1149 improves blood glucose control in patients with type 2 diabetes mellitus
Geerling_2008_Transplantation_85_135 Innervation and secretory function of transplanted human submandibular salivary glands
Genovese_2008_Toxicology_244_123 Determination of miosis threshold from whole-body vapor exposure to sarin in African green monkeys
Ghadimi_2008_J.Enzyme.Inhib.Med.Chem_23_213 Synthesis, lipophilicity study and in vitro evaluation of some rodenticides as acetylcholinesterase reversible inhibitors
Ghareeb_2008_Neurosci.Lett_436_44 Vanadium improves brain acetylcholinesterase activity on early stage alloxan-diabetic rats
Ghila_2008_Eur.J.Neurosci_27_621 The evolutionarily conserved gene LNP-1 is required for synaptic vesicle trafficking and synaptic transmission
Gil-Neciga_2008_Rev.Neurol_46_461 [Treatment pattern of Alzheimer's disease with cholinesterase inhibitors (TRAIN study)]
Girardi_2008_Am.J.Physiol.Renal.Physiol_294_F414 Dipeptidyl peptidase IV inhibition downregulates Na+ - H+ exchanger NHE3 in rat renal proximal tubule
Golomb_2008_Proc.Natl.Acad.Sci.U.S.A_105_4295 Acetylcholinesterase inhibitors and Gulf War illnesses
Goptar_2008_Biochimie_90_508 Localization of post-proline cleaving peptidases in Tenebrio molitor larval midgut
Graewin_2008_J.Am.Coll.Surg_206_503 Leptin regulates gallbladder genes related to gallstone pathogenesis in leptin-deficient mice
Greenfield_2008_FEBS.J_275_604 Non-hydrolytic functions of acetylcholinesterase. The significance of C-terminal peptides
Gundogdu_2008_Acta.Cardiol_63_197 Association between -514C-->T polymorphism of the hepatic lipase gene and coronary artery disease in a Turkish population
Gupta_2008_Int.J.Biol.Macromol_42_145 Comparative study of performances of lipase immobilized asymmetric polysulfone and polyether sulfone membranes in olive oil hydrolysis
Hauer_2008_Dev.Med.Child.Neurol_50_68 Central hypothermia as a cause of acute pancreatitis in children with neurodevelopmental impairment
Hedberg_2008_Neurosci_152_223 Transgenic mice overexpressing human acetylcholinesterase and the Swedish amyloid precursor protein mutation: effect of nicotine treatment
Hofer_2008_Crit.Care.Med_36_404 Pharmacologic cholinesterase inhibition improves survival in experimental sepsis
Hofmann_2008_Am.J.Ind.Med_51_532 Evaluation of a clinic-based cholinesterase test kit for the Washington State Cholinesterase Monitoring Program
Hoizey_2008_J.Forensic.Sci_53_499 Thiodicarb and methomyl tissue distribution in a fatal multiple compounds poisoning
Holland_2008_J.Anal.Toxicol_32_116 Modifications to the organophosphorus nerve agent-protein adduct refluoridation method for retrospective analysis of nerve agent exposures
Holst_2008_Trends.Mol.Med_14_161 Glucagon-like peptide-1, glucose homeostasis and diabetes
Holtzheimer_2008_Int.J.Geriatr.Psychiatry_23_625 A double blind, placebo-controlled pilot study of galantamine augmentation of antidepressant treatment in older adults with major depression
Hooper_2008_Ann.Clin.Biochem_45_102 Familial lipoprotein lipase deficiency caused by known (G188E) and novel (W394X) LPL gene mutations
Hosokawa_2008_Molecules_13_412 Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs
Hung_2008_Biol.Pharm.Bull_31_159 Anti-amnestic activity of pseudocoptisine from Corydalis Tuber
Iijima_2008_J.Hum.Genet_53_193 Association of an intronic haplotype of the LIPC gene with hyperalphalipoproteinemia in two independent populations
Inestrosa_2008_FEBS.J_275_625 Amyloid-cholinesterase interactions. Implications for Alzheimer's disease
Inzucchi_2008_Circulation_117_574 New drugs for the treatment of diabetes: part II: Incretin-based therapy and beyond
Ito_2008_Chem.Biol.Interact_175_346 Viral vector-mediated [corrected] expression of human collagen Q in cultured cells
Ivanova_2008_Colloids.Surf.B.Biointerfaces_63_91 Action of Humicola lanuginosa lipase on mixed monomolecular films of tricaprylin and polyethylene glycol stearate
Jang_2008_Arch.Pharm.Res_31_666 A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta
Jean_2008_PLoS.One_3_e1834 Structural elements regulating amyloidogenesis: a cholinesterase model system
Jennings_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_149_401 Acetylcholinesterase in the sea urchin Lytechinus variegatus: characterization and developmental expression in larvae
Jeong_2008_Appl.Biochem.Biotechnol_148_131 Lipase-catalyzed transesterification of rapeseed oil for biodiesel production with tert-butanol
Jeong_2008_Cell.Metab_7_227 Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
Jiang_2008_FEBS.J_275_612 Acetylcholinesterase and apoptosis. A novel perspective for an old enzyme
Jiang_2008_BMC.Biotechnol_8_4 Efficient display of active lipase LipB52 with a Pichia pastoris cell surface display system and comparison with the LipB52 displayed on Saccharomyces cerevisiae cell surface
Jocken_2008_Metabolism_57_326 Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene
John_2008_Eur.J.Med.Res_13_73 N-terminal acetylation protects glucagon-like peptide GLP-1-(7-34)-amide from DPP-IV-mediated degradation retaining cAMP- and insulin-releasing capacity
Jun_2008_Drug.Chem.Toxicol_31_1 Potency of novel oximes to reactivate sarin inhibited human cholinesterases
Jun_2008_J.Chromatogr.Sci_46_316 TLC analysis of intermediates arising during the preparation of oxime HI-6 dimethanesulfonate
Kammoun_2008_Pancreas_36_302 Purification and characterization of the first reptile pancreatic lipase: the turtle
Kanai_2008_J.Clin.Lab.Anal_22_66 Liver function tests in patients with bacteremia
Karanth_2008_Regul.Toxicol.Pharmacol_50_200 Selective inhibition of butyrylcholinesterase in vivo in horses by the feed-through larvacide Equitrol
Kasprowicz_2008_Bull.Entomol.Res_98_115 Clonal turnover of MACE-carrying peach-potato aphids (Myzus persicae (Sulzer), Homoptera: Aphididae) colonizing Scotland
Kaur_2008_J.Neurosci_28_491 Effects of ibotenate and 192IgG-saporin lesions of the nucleus basalis magnocellularis\/substantia innominata on spontaneous sleep and wake states and on recovery sleep after sleep deprivation in rats
Kaur_2008_Brain.Cogn_67_25 Effects of green tea extract on learning, memory, behavior and acetylcholinesterase activity in young and old male rats
Kersten_2008_PPAR.Res_2008_132960 Peroxisome proliferator activated receptors and lipoprotein metabolism
Key_2008_J.Environ.Sci.Health.B_43_50 Effects of the anti-fouling herbicide Irgarol 1051 on two life stages of the grass shrimp, Palaemonetes pugio
Khajamohiddin_2008_Crit.Rev.Microbiol_34_13 Biodegradation of aromatic compounds: an overview of meta-fission product hydrolases
Kienesberger_2008_J.Biol.Chem_283_5908 Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase
Kim_2008_J.Microbiol_46_100 Cloning and characterization of thermostable esterase from Archaeoglobus fulgidus
Kim_2008_World.J.Gastroenterol_14_2401 Is there correlation between pancreatic enzyme and radiological severity in acute pancreatitis?
Kolarich_2008_Proteomics_8_254 Glycoproteomic characterization of butyrylcholinesterase from human plasma
Kurrikoff_2008_Eur.J.Neurosci_27_2147 Stress-induced analgesia in mice: evidence for interaction between endocannabinoids and cholecystokinin
Kuswandi_2008_Talanta_74_613 An optical fiber biosensor for chlorpyrifos using a single sol-gel film containing acetylcholinesterase and bromothymol blue
Laalou_2008_Anesthesiology_108_888 Involvement of the basal cholinergic forebrain in the mediation of general (propofol) anesthesia
Lagarce_2008_Presse.Med_37_435 [Jimson Weed poisoning: an antidote is available in France]
Landmark_2008_Tidsskr.Nor.Laegeforen_128_294 [Cholinesterase inhibitors in the treatment of dementia--are they useful in clinical practice?]
Lane_2008_Pharmacogenet.Genomics_18_289 Synergistic effect of apolipoprotein E epsilon4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease
Leduc_2008_Neurodegener.Dis_5_225 Polymorphisms at the paraoxonase 1 L55M and Q192R loci affect the pathophysiology of Alzheimer's disease: emphasis on the cholinergic system and beta-amyloid levels
Lee_2008_J.Microbiol.Biotechnol_18_465 Development of magnetically separable immobilized lipase by using cellulose derivatives and their application in enantioselective esterification of ibuprofen
Lee_2008_J.Biotechnol_133_486 Lipase-catalyzed synthesis of glucose fatty acid ester using ionic liquids mixtures
Lee_2008_J.Gene.Med_10_260 Adenoviral vector-mediated glucagon-like peptide 1 gene therapy improves glucose homeostasis in Zucker diabetic fatty rats
Leroy_2008_Biofouling_24_11 Effects of commercial enzymes on the adhesion of a marine biofilm-forming bacterium
Leticia_2008_Ecotoxicol.Environ.Saf_71_787 Determination of esterase activity and characterization of cholinesterases in the reef fish Haemulon plumieri
Levano_2008_Anesth.Analg_106_147 Rapid and accurate detection of atypical and Kalow variants in the butyrylcholinesterase gene using denaturing high performance liquid chromatography
Li_2008_J.Pharmacol.Exp.Ther_324_1146 The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency
Li_2008_Biochem.J_411_425 Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers
Li_2008_Zhong.Xi.Yi.Jie.He.Xue.Bao_6_25 [A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment]
Li_2008_Cochrane.Database.Syst.Rev__CD005592 Huperzine A for Alzheimer's disease
Li_2008_Ecotoxicol.Environ.Saf_71_781 Effects of nonylphenol on cholinesterase and carboxylesterase activities in male guppies (Poecilia reticulata)
Li_2008_Hepatobiliary.Pancreat.Dis.Int_7_40 Prognostic factors for chronic severe hepatitis and construction of a prognostic model
Liang_2008_Org.Lett_10_193 Highly efficient asymmetric synthesis of fluvirucinine A1 via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)-lipase-catalyzed acetylation tandem process
Little_2008_Expert.Opin.Investig.Drugs_17_209 An update on huperzine A as a treatment for Alzheimer's disease
Liu_2008_J.Endocrinol_196_57 Glucagon-like peptide-1 attenuates tumour necrosis factor-alpha-mediated induction of plasminogen [corrected] activator inhibitor-1 expression
Liu_2008_Development_135_1957 Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning
Liu_2008_J.Zhejiang.Univ.Sci.B_9_44 Effects of over-expressing resistin on glucose and lipid metabolism in mice
Loizzo_2008_Curr.Med.Chem_15_1209 Natural products and their derivatives as cholinesterase inhibitors in the treatment of neurodegenerative disorders: an update
Loizzo_2008_J.Med.Food_11_184 Influence of ripening stage on health benefits properties of Capsicum annuum var. acuminatum L.: in vitro studies
Lopes_2008_Lett.Appl.Microbiol_46_255 Yarrowia lipolytica lipase production enhanced by increased air pressure
Lorke_2008_J.Appl.Toxicol_28_422 In vitro oxime protection of human red blood cell acetylcholinesterase inhibited by diisopropyl-fluorophosphate
Lorke_2008_Curr.Med.Chem_15_743 Entry of oximes into the brain: a review
Lu_2008_Eur.J.Med.Chem_43_1603 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors
Luchanok_2008_Curr.Opin.Neurol_21_8 Ocular myasthenia: diagnostic and treatment recommendations and the evidence base
Luckenbach_2008_Reprod.Biol.Endocrinol_6_2 Identification of differentially expressed ovarian genes during primary and early secondary oocyte growth in coho salmon, Oncorhynchus kisutch
Ludanyi_2008_J.Neurosci_28_2976 Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus
Lyberg_2008_Biochim.Biophys.Acta_1784_343 Lipase specificity towards eicosapentaenoic acid and docosahexaenoic acid depends on substrate structure
Lyle_2008_Dement.Geriatr.Cogn.Disord_25_226 Treatment of a whole population sample of Alzheimer's disease with donepezil over a 4-year period: lessons learned
Mahadeva_2008_Semin.Neurol_28_212 Autoimmune disorders of neuromuscular transmission
Mateo_2008_Eur.J.Neurol_15_219 Gene-gene interaction between 14-3-3 zeta and butyrylcholinesterase modulates Alzheimer's disease risk
Mihaylova_2008_Brain_131_747 Clinical and molecular genetic findings in COLQ-mutant congenital myasthenic syndromes
Mitchell_2008_J.Biotechnol_133_343 An analytical method for determining relative specificities for sequential reactions catalyzed by the same enzyme: application to the hydrolysis of triacylglycerols by lipases
Mitsunaga_2008_Pancreas_36_241 Low serum level of cholinesterase at recurrence of pancreatic cancer is a poor prognostic factor and relates to systemic disorder and nerve plexus invasion
Miyawaki_2008_J.Biosci.Bioeng_105_61 Lipase-catalyzed butanolysis of triolein in ionic liquid and selective extraction of product using supercritical carbon dioxide
Mochida_2008_Environ.Toxicol.Chem_27_367 Early life-stage toxicity test for copper pyrithione and induction of skeletal anomaly in a teleost, the mummichog (Fundulus heteroclitus)
Mohammadi_2008_Toxicology_244_42 Synaptosomal GABA uptake decreases in paraoxon-treated rat brain
Montenegro_2008_Chem.Biol.Interact_175_336 The level of aryl acylamidase activity displayed by human butyrylcholinesterase depends on its molecular distribution
Moreno_2008_Toxicol.Lett_176_162 Long-term monoamine changes in the striatum and nucleus accumbens after acute chlorpyrifos exposure
Mossello_2008_Dement.Geriatr.Cogn.Disord_25_372 Is antidepressant treatment associated with reduced cognitive decline in Alzheimer's disease?
Mukadam_2008_Int.Psychogeriatr_20_209 Cholinesterase inhibitors for delirium: what is the evidence?
Munoz-Delgado_2008_Chem.Biol.Interact_175_340 The expression of cholinesterases in human renal tumours varies according to their histological types
Nawa_2008_Anticancer.Agents.Med.Chem_8_232 Gene directed enzyme prodrug therapy for ovarian cancer: could GDEPT become a promising treatment against ovarian cancer?
Nawaz_2008_J.Enzyme.Inhib.Med.Chem_23_206 Structural insight into the inhibition of acetylcholinesterase by 2,3,4, 5-tetrahydro-1, 5-benzothiazepines
Ndjakou_2008_Chem.Pharm.Bull.(Tokyo)_56_222 Anti-plasmodial and cholinesterase inhibiting activities of some constituents of Psorospermum glaberrimum
Neumiller_2008_Diabetes.Educ_34_183 Looking to the future: focus on DPP-4 inhibitors for the treatment of type 2 diabetes and emerging therapies
Okada_2008_J.Food.Sci_73_C146 Production of n-3 polyunsaturated fatty acid concentrate from sardine oil by immobilized Candida rugosa lipase
Olivo_2008_Clin.Dev.Immunol_2008_794050 Methotrexate and cyclosporine treatments modify the activities of dipeptidyl peptidase IV and prolyl oligopeptidase in murine macrophages
Oshio_2008_J.Pediatr.Surg_43_222 Imperforate anus, malrotation, and Hirschsprung's disease with double zonal aganglionosis: an extremely rare combination
Overshott_2008_Cochrane.Database.Syst.Rev__CD005317 Cholinesterase inhibitors for delirium
Pacheco_2008_Pediatr.Dev.Pathol_11_274 Variability of acetylcholinesterase hyperinnervation patterns in distal rectal suction biopsy specimens in Hirschsprung disease
Pallasch_2008_Leukemia_22_585 Targeting lipid metabolism by the lipoprotein lipase inhibitor orlistat results in apoptosis of B-cell chronic lymphocytic leukemia cells
Paraoanu_2008_FEBS.J_275_618 Acetylcholinesterase in cell adhesion, neurite growth and network formation
Park_2008_BMB.Rep_41_254 Purification and characterization of hepatic lipase from Todarodes pacificus
Parthimos_2008_Clin.Chem.Lab.Med_46_137 The in vivo and in vitro effects of L-carnitine supplementation on the erythrocyte membrane acetylcholinesterase, Na+, K+-ATPase and Mg2+-ATPase activities in basketball players
Passmore_2008_Drugs.Aging_25_381 Alternatives to atypical antipsychotics for the management of dementia-related agitation
Pchelintsev_2008_Anal.Chim.Acta_612_190 A novel procedure for rapid surface functionalisation and mediator loading of screen-printed carbon electrodes
Pedersen_2008_Regul.Pept_146_310 Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects
Pelton_2008_Int.J.Geriatr.Psychiatry_23_670 Randomized double-blind placebo-controlled donepezil augmentation in antidepressant-treated elderly patients with depression and cognitive impairment: a pilot study
Peter_2008_Lancet_371_622 In-laws, insecticide--and a mimic of brain death
Pigot_2008_J.ECT_24_57 Pharmacological attenuation of electroconvulsive therapy--induced cognitive deficits: theoretical background and clinical findings
Porsteinsson_2008_Curr.Alzheimer.Res_5_83 Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial
Pospisil_2008_Photochem.Photobiol.Sci_7_625 Photochemical synthesis of substituted indan-1-ones related to donepezil
Poupardin_2008_Insect.Biochem.Mol.Biol_38_540 Cross-induction of detoxification genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti: impact on larval tolerance to chemical insecticides
Puech-Guenot_2008_J.Biomol.Screen_13_72 Small-scale production of Burkholderia cepacia ATCC21808 lipase adapted to high-throughput screening
Qaseem_2008_Ann.Intern.Med_148_370 Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians
Qin_2008_Invest.Ophthalmol.Vis.Sci_49_1274 Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells
Raina_2008_Ann.Intern.Med_148_379 Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline
Raveh_2008_Toxicol.Appl.Pharmacol_227_155 Efficacy of antidotal treatment against sarin poisoning: the superiority of benactyzine and caramiphen
Razay_2008_Expert.Rev.Neurother_8_9 Galantamine in Alzheimer's disease
Redig_2008_Vet.Clin.North.Am.Exot.Anim.Pract_11_261 Raptor toxicology
Remmler_2008_Expert.Opin.Pharmacother_9_363 Pharmacogenomics in acute coronary syndrome
Richter_2008_Cochrane.Database.Syst.Rev__CD006739 Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus
Rocha-Rego_2008_Brain.Res.Bull_76_26 Architectonic subdivisions of the amygdalar complex of a primitive marsupial (Didelphis aurita)
Rodriguez_2008_Anal.Biochem_375_196 Novel chromatographic resolution of chiral diacylglycerols and analysis of the stereoselective hydrolysis of triacylglycerols by lipases
Roegge_2008_Brain.Res.Bull_75_166 Developmental diazinon neurotoxicity in rats: later effects on emotional response
Ross_2008_Dev.Neurobiol_68_409 Capabilities of neurexins in the chick ciliary ganglion
Rowland_2008_Chem.Biol.Interact_175_73 Inactivation of an invertebrate acetylcholinesterase by sulfhydryl reagents: a reconsideration of the implications for insecticide design
Rozengart_2008_Dokl.Biochem.Biophys_418_1 New substrates and reversible inhibitors of cholinesterases based on esters and thioesters of noncholine cyclic ammonium alcohols
Russon_2008_Anaesthesia_63_210 Drug incompatibility reaction with use of fluorescein during anaesthesia
Sagiroglu_2008_Artif.Cells.Blood.Substit.Immobil.Biotechnol_36_138 Conversion of sunflower oil to biodiesel by alcoholysis using immobilized lipase
Saied_2008_J.Asian.Nat.Prod.Res_10_515 Two new coumarins from Murraya paniculata
Sanogo_2008_J.Med.Entomol_45_203 Identification of male specimens of the Culex pipiens complex (Diptera: Culicidae) in the hybrid zone using morphology and molecular techniques
Saulsbury_2008_Toxicology_244_98 Characterization of chlorpyrifos-induced apoptosis in placental cells
Saxena_2008_Eur.J.Pharmacol_581_283 Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice
Sega_2008_Clin.Chim.Acta_389_177 New organophosphorus compounds: cholinesterases inhibition, cytotoxicity and lethal dose
Shields_2008_AANA.J_76_41 Heart block and prolonged Q-Tc interval following muscle relaxant reversal: a case report
Shua-Haim_2008_Clin.Drug.Investig_28_361 Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study
Skorinkin_2008_Gen.Physiol.Biophys_27_19 Model of concentration changes across the synaptic cleft during a single quantum release
Slotkin_2008_Environ.Health.Perspect_116_340 Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems
Slotkin_2008_Brain.Res.Bull_75_640 Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood
Solano_2008_J.Anal.Toxicol_32_68 Quantification of nerve agent VX-butyrylcholinesterase adduct biomarker from an accidental exposure
Soreq_2008_FEBS.J_275_603 Introduction: cholinesterases, from molecular complexity to non-hydrolytic functions
Soulimane-Mokhtari_2008_Gen.Physiol.Biophys_27_3 Serum lipoprotein composition, lecithin cholesterol acyltransferase and tissue lipase activities in pregnant diabetic rats and their offspring receiving enriched n-3 PUFA diet
Sparks_2008_Crit.Care.Nurs.Q_31_65 Inpatient care for persons with Alzheimer's disease
Srain_2008_J.Environ.Sci.Health.B_43_75 Alteration of acetylcholinesterase activity in Semele solida (MOLLUSCA: SEMELIDAE) as a biochemical response to coastal anthropogenic impact
Starr_2008_BMC.Psychiatry_8_27 Estimated pre-morbid IQ effects on cognitive and functional outcomes in Alzheimer disease: a longitudinal study in a treated cohort
Stefano_2008_Sci.Total.Environ_392_99 Cholinesterase activities in the scallop Pecten jacobaeus: characterization and effects of exposure to aquatic contaminants
Steiner_2008_Vet.Ther_9_37 Serum pancreatic lipase immunoreactivity concentrations in dogs treated with potassium bromide and\/or phenobarbital
Stevens_2008_Pharmacotherapy_28_403 Olanzapine-associated neuroleptic malignant syndrome in a patient receiving concomitant rivastigmine therapy
Streit_2008_Biol.Chem_389_149 Evaluation of the 'side door' in carboxylesterase-mediated catalysis and inhibition
Sun_2008_Eur.J.Neurol_15_278 How long can patients with mild or moderate Alzheimer's dementia maintain both the cognition and the therapy of cholinesterase inhibitors: a national population-based study
Sunazuka_2008_Acc.Chem.Res_41_302 Efficient total synthesis of novel bioactive microbial metabolites
Szeltner_2008_Curr.Protein.Pept.Sci_9_96 Structure, function and biological relevance of prolyl oligopeptidase
Taldone_2008_Bioorg.Med.Chem.Lett_18_479 Inhibition of dipeptidyl peptidase-IV (DPP-IV) by atorvastatin
Tang_2008_Cancer.Invest_26_178 Carboxylesterase 2 is downregulated in colorectal cancer following progression of the disease
Tarhoni_2008_Biomarkers_13_343 Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides
Taylor_2008_Inhal.Toxicol_20_465 Acute toxic effects of inhaled dichlorvos vapor on respiratory mechanics and blood cholinesterase activity in guinea pigs
Timofeeva_2008_Neurotoxicol.Teratol_30_38 Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon
Trevisan_2008_Basic.Clin.Pharmacol.Toxicol_102_365 Antioxidant and acetylcholinesterase response to repeated malathion exposure in rat cerebral cortex and hippocampus
Trodler_2008_J.Chromatogr.A_1179_161 Rational design of a new one-step purification strategy for Candida antarctica lipase B by ion-exchange chromatography
Trodler_2008_BMC.Struct.Biol_8_9 Modeling structure and flexibility of Candida antarctica lipase B in organic solvents
Uchino_2008_Cancer.Gene.Ther_15_94 Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan
Vahl_2008_Anal.Chim.Acta_610_44 A potential high-throughput method for the determination of lipase activity by potentiometric flow injection titrations
Vaitkevicius_2008_Ann.Anat_190_158 Innervation of pulmonary veins: morphologic pattern and pathways of nerves in the human fetus
Valdes-Ramirez_2008_Talanta_74_741 Sensitive amperometric biosensor for dichlorovos quantification: Application to detection of residues on apple skin
van der Schans_2008_J.Anal.Toxicol_32_125 Verification of exposure to cholinesterase inhibitors: generic detection of OPCW Schedule 1 nerve agent adducts to human butyrylcholinesterase
van Gammeren_2008_Transfus.Med_18_134 Fresh frozen plasma transfusion for reversal of prolonged post-anaesthesia apnoea
Vandevoorde_2008_Curr.Top.Med.Chem_8_247 Overview of the chemical families of fatty acid amide hydrolase and monoacylglycerol lipase inhibitors
Varo_2008_Aquat.Toxicol_88_53 Acute toxicity of dichlorvos to Aphanius iberus (Cuvier & Valenciennes, 1846) and its anti-cholinesterase effects on this species
Vernino_2008_Neurology_70_1926 Invited Article: Autonomic ganglia: target and novel therapeutic tool
Vihervaara_2008_J.Mol.Biol_376_1215 dFOXO regulates transcription of a Drosophila acid lipase
Vilalta-Franch_2008_Rev.Neurol_46_13 [Metabolic syndrome in Alzheimer's disease: clinical and developmental influences]
Vilalta-Franch_2008_Rev.Neurol_46_129 [Mortality rates in patients with Alzheimer's disease treated with atypical neuroleptic drugs]
Viso_2008_Curr.Top.Med.Chem_8_231 The medicinal chemistry of agents targeting monoacylglycerol lipase
Voelker_2008_JAMA_299_1763 Guideline: dementia drugs' benefits uncertain
Volicer_2008_J.Nutr.Health.Aging_12_125 Editorial: clinical neurosciences in the Journal of Nutrition Health and Aging
Vuksic_2008_Coll.Antropol_32 Suppl 1_155 Structural basis of developmental plasticity in the corticostriatal system
Wahlen_2008_J.Lipid.Res_49_607 The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis
Wang_2008_Appl.Radiat.Isot_66_506 Facile synthesis of new carbon-11 labeled conformationally restricted rivastigmine analogues as potential PET agents for imaging AChE and BChE enzymes
Watanabe_2008_J.Pharmacol.Sci_106_84 Spatial memory impairment without apoptosis induced by the combination of beta-amyloid oligomers and cerebral ischemia is related to decreased acetylcholine release in rats
Weinstock_2008_Chem.Biol.Interact_175_216 Rational design of a drug for Alzheimer's disease with cholinesterase inhibitory and neuroprotective activity
Wheelock_2008_Rev.Environ.Contam.Toxicol_195_117 Applications of carboxylesterase activity in environmental monitoring and toxicity identification evaluations (TIEs)
Widder_2008_Aquat.Toxicol_88_9 Tadpole size, cholinesterase activity, and swim speed in four frog species after exposure to sub-lethal concentrations of chlorpyrifos
Widmann_2008_BMC.Genomics_9_207 Analysis of the distribution of functionally relevant rare codons
Worek_2008_Toxicology_244_35 Inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds: pig versus minipig acetylcholinesterase
Wright_2008_Atherosclerosis_199_187 Genetic screening of the LPL gene in hypertriglyceridaemic patients
Wu_2008_J.Med.Invest_55_61 NO-1886, a lipoprotein lipase activator, attenuates contraction of rat intestinal ring preparations
Xiao_2008_J.Agric.Food.Chem_56_910 Investigation of the mechanism of enhanced effect of EGCG on huperzine A's inhibition of acetylcholinesterase activity in rats by a multispectroscopic method
Xu_2008_Protein.Sci_17_601 Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design
Yamamoto_2008_Org.Biomol.Chem_6_1540 Enzymatic resolution and evaluation of enantiomers of cis-5'-hydroxythalidomide
Yan_2008_Wei.Sheng.Wu.Xue.Bao_48_184 [Cloning and overexpression of lipase gene from Geotrichum candidum Y162]
Yang_2008_Toxicol.Appl.Pharmacol_228_32 Chlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesterase
Yu_2008_World.J.Pediatr_4_8 Glucagon-like peptide 1 based therapy for type 2 diabetes
Zahodne_2008_CNS.Spectr_13_26 Course, prognosis, and management of psychosis in Parkinson's disease: are current treatments really effective?
Zawisza-Raszka_2008_Acta.Biol.Hung_59_31 Acetylcholinesterase, catalase and glutathione S-transferase activity in beet armyworm (Spodoptera exigua) exposed to nickel and\/or diazinon
Zhang_2008_Nan.Fang.Yi.Ke.Da.Xue.Xue.Bao_28_225 [Effects of huperzine A on cognitive function of rats recovering from general anesthesia]
Zhang_2008_J.Nutr_138_515 Lipid metabolism in diet-induced obese rabbits is similar to that of obese humans
Zhao_2008_Zhongguo.Zhong.Xi.Yi.Jie.He.Za.Zhi_28_234 [Effect of Gengnianchun Recipe on learning memory function and hippocampal cholinergic system in ovariectomized rats]
Zhao_2008_J.Ind.Microbiol.Biotechnol_35_189 Scale-up fermentation of recombinant Candida rugosa lipase expressed in Pichia pastoris using the GAP promoter
Zheng_2008_Org.Biomol.Chem_6_836 Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction
Zheng_2008_Chin.Med.J.(Engl)_121_99 Repair of brachial plexus lower trunk injury by transferring brachialis muscle branch of musculocutaneous nerve: anatomic feasibility and clinical trials
Zhou_2008_J.Phys.Chem.B_112_270 Continuum simulations of acetylcholine consumption by acetylcholinesterase: a Poisson-Nernst-Planck approach
Zvonok_2008_J.Proteome.Res_7_2158 Full mass spectrometric characterization of human monoacylglycerol lipase generated by large-scale expression and single-step purification
Abada_2008_Pak.J.Biol.Sci_11_1100 Production and characterization of a mesophilic lipase isolated from Bacillus stearothermophilus AB-1
Abdel-Latief_2008_Proc.Natl.Acad.Sci.U.S.A_105_8914 An epoxide hydrolase involved in the biosynthesis of an insect sex attractant and its use to localize the production site
Ahmad_2008_J.Enzyme.Inhib.Med.Chem_23_313 Butyrylcholinesterase, lipoxygenase inhibiting and antifungal alkaloids from Isatis tinctoria
Ahren_2008_Vasc.Health.Risk.Manag_4_383 Novel combination treatment of type 2 diabetes DPP-4 inhibition + metformin
Akasofu_2008_Chem.Biol.Interact_175_222 Study of neuroprotection of donepezil, a therapy for Alzheimer's disease
Algorta_2008_Methods.Find.Exp.Clin.Pharmacol_30_141 Phase I clinical trial with desoxypeganine, a new cholinesterase and selective MAO-A inhibitor: tolerance and pharmacokinetics study of escalating single oral doses
Alloue_2008_Prep.Biochem.Biotechnol_38_217 Effect of monopropylene glycol and gamma irradiation on Yarrowia lipolytica lipase stabilization
Aman_2008_Child.Adolesc.Psychiatr.Clin.N.Am_17_713 Treatment of inattention, overactivity, and impulsiveness in autism spectrum disorders
Amitai_2008_Chem.Biol.Interact_175_249 Characterization of asymmetric fluorogenic phosphonates as probes for developing organophosphorus hydrolases with broader stereoselectivity
Amoozegar_2008_J.Basic.Microbiol_48_160 Production of an extracellular thermohalophilic lipase from a moderately halophilic bacterium, Salinivibrio sp. strain SA-2
Anand_2008_J.Insect.Physiol_54_1323 Tissue and stage-specific juvenile hormone esterase (JHE) and epoxide hydrolase (JHEH) enzyme activities and Jhe transcript abundance in lines of the cricket Gryllus assimilis artificially selected for plasma JHE activity: implications for JHE microevolution
Anglister_2008_Chem.Biol.Interact_175_92 Cholinesterases in development and disease
Antonio-Santos_2008_Curr.Opin.Ophthalmol_19_468 Medical treatment options for ocular myasthenia gravis
Anzellotti_2008_Clin.Neuropharmacol_31_231 Delayed blink reflex in dementia with Lewy bodies is sensitive to cholinergic modulation
Armutlu_2008_BMC.Bioinformatics_9_411 Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
Ashwell_2008_Somatosens.Mot.Res_25_171 Topography and chemoarchitecture of the striatum and pallidum in a monotreme, the short-beaked echidna (Tachyglossus aculeatus)
Assal_2008_J.Am.Geriatr.Soc_56_946 Galantamine improves gait performance in patients with Alzheimer's disease
Backlund_2008_J.Biotechnol_135_358 Fedbatch design for periplasmic product retention in Escherichia coli
Backman_2008_Anesthesiology_108_965\; author reply 965 Anticholinesterase drugs and the transplanted heart
Badiou_2008_Chem.Biol.Interact_175_410 Hysteresis of insect acetylcholinesterase
Bajgar_2008_Chem.Biol.Interact_175_281 An attempt to assess functionally minimal acetylcholinesterase activity necessary for survival of rats intoxicated with nerve agents
Bank_2008_Front.Biosci_13_3699 Inflammatory bowel diseases: multiple benefits from therapy with dipeptidyl- and alanyl-aminopeptidase inhibitors
Baptista_2008_Biopolymers_89_538 Thermodynamics and mechanism of cutinase stabilization by trehalose
Barohn_2008_Ann.N.Y.Acad.Sci_1132_225 Treatment and clinical research in myasthenia gravis: how far have we come?
Barton_2008_Am.J.Geriatr.Pharmacother_6_147 Contraindicated medication use among patients in a memory disorders clinic
Basova_2008_Dokl.Biochem.Biophys_419_69 Cholinesterase hydrolysis of substituted lupinine benzoates
Beck_2008_Chem.Biol.Interact_175_200 Hydrolysis of nerve agents by model nucleophiles: a computational study
Belbahri_2008_Gene_408_1 Evolution of the cutinase gene family: evidence for lateral gene transfer of a candidate Phytophthora virulence factor
Ben Rebah_2008_Appl.Biochem.Biotechnol_151_71 Inhibitory effects of tunisian marine algal extracts on digestive lipases
Bennett_2008_Aust.N.Z.J.Psychiatry_42_662 Dual constraints on synapse formation and regression in schizophrenia: neuregulin, neuroligin, dysbindin, DISC1, MuSK and agrin
Bertrand_2008_Chem.Biol.Interact_175_113 Effect of fluoxetine on neuromuscular function in acetylcholinesterase (AChE) knockout mice
Bhanushali_2008_Neurology_71_1335 Treatment of ocular symptoms in myasthenia gravis
Bionaz_2008_J.Dairy.Sci_91_2808 Characterization of Madin-Darby bovine kidney cell line for peroxisome proliferator-activated receptors: temporal response and sensitivity to fatty acids
Bjarnason_2008_Hum.Exp.Toxicol_27_253 Comparison of selected skin decontaminant products and regimens against VX in domestic swine
Boiko_2008_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_108_45 [The use of axamon in the complex rehabilitation of patients with movement disorders in the pathology of lumbar spine]
Bolognesi_2008_Mini.Rev.Med.Chem_8_960 From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease
Bonzini_2008_Aquat.Toxicol_89_1 Effects of river pollution on the colonisation of artificial substrates by macrozoobenthos
Bosak_2008_Chem.Biol.Interact_175_192 Stereoselective inhibition of human, mouse, and horse cholinesterases by bambuterol enantiomers
Bourne_2008_J.Psychosom.Res_65_273 Drug treatment of delirium: past, present and future
Breitbart_2008_Clin.J.Oncol.Nurs_12_27 Pharmacologic treatment options for cancer-related fatigue: current state of clinical research
Brenes_2008_Poult.Sci_87_2300 Effect of enzyme addition on the nutritive value of high oleic acid sunflower seeds in chicken diets
Bruns_2008_Biotechnol.Bioeng_101_19 Amphiphilic conetworks as activating carriers for the enhancement of enzymatic activity in supercritical CO2
Buhl_2008_J.Exp.Biol_211_2346 A muscarinic cholinergic mechanism underlies activation of the central pattern generator for locust flight
Burdon_2008_Diab.Vasc.Dis.Res_5_128 Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study
Burns_2008_Drugs.Aging_25_707 Defining treatment response to donepezil in Alzheimer's disease: responder analysis of patient-level data from randomized, placebo-controlled studies
Butler_2008_Curr.Med.Chem_15_1737 Recent developments in the design of anti-depressive therapies: targeting the serotonin transporter
Campbell_2008_Diabetes.Educ_34_518 More choices than ever before: emerging therapies for type 2 diabetes
Carlson_2008_J.Biochem.Mol.Toxicol_22_187 Distribution of SH-SY5Y human neuroblastoma cells in the cell cycle following exposure to organophosphorus compounds
Carolan_2008_Chem.Biol.Interact_175_293 Novel isosorbide di-ester compounds as inhibitors of acetylcholinesterase
Carol-Visser_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_870_91 Development of an automated on-line pepsin digestion-liquid chromatography-tandem mass spectrometry configuration for the rapid analysis of protein adducts of chemical warfare agents
Cerpa_2008_Curr.Alzheimer.Res_5_233 Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses
Chan_2008_Drugs.Aging_25_761 Transdermal delivery of treatment for Alzheimer's disease: development, clinical performance and future prospects
Chappell_2008_Eur.Respir.J_32_931 Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD
Che_2008_Inhal.Toxicol_20_821 Blood and bronchoalveolar lavage fluid acetylcholinesterase levels following microinstillation inhalation exposure to sarin in Guinea pigs
Chen_2008_Taiwan.J.Obstet.Gynecol_47_283 Prenatal diagnosis, fetal surgery, recurrence risk and differential diagnosis of neural tube defects
Chen_2008_Appl.Biochem.Biotechnol_151_21 Highly efficient regioselective synthesis of 5'-O-lauroyl-5-azacytidine catalyzed by Candida antarctica Lipase B
Cheng_2008_Chem.Biol.Interact_175_196 Acetylcholinesterase: mechanisms of covalent inhibition of H447I mutant determined by computational analyses
Chilukuri_2008_Chem.Biol.Interact_175_327 Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo
Chilukuri_2008_Chem.Biol.Interact_175_255 Effect of polyethylene glycol modification on the circulatory stability and immunogenicity of recombinant human butyrylcholinesterase
Choi_2008_Chem.Biol.Interact_175_76 Regulation of PRiMA-linked G(4) AChE by a cAMP-dependent signaling pathway in cultured rat pheochromocyoma PC12 cells
Choi_2008_Arch.Pharm.Res_31_183 Beta-secretase (BACE1) inhibitors from Perilla frutescens var. acuta
Choi_2008_Appl.Microbiol.Biotechnol_79_61 Production of (R)-ethyl-3,4-epoxybutyrate by newly isolated Acinetobacter baumannii containing epoxide hydrolase
Chomsung_2008_J.Comp.Neurol_510_24 Ultrastructural examination of diffuse and specific tectopulvinar projections in the tree shrew
Ciumas_2008_Curr.Opin.Neurol_21_431 Magnetic resonance imaging in clinical trials
Coley_2008_Neuroepidemiology_31_69 Predictive factors of attrition in a cohort of Alzheimer disease patients. The REAL.FR study
Comoletti_2008_Chem.Biol.Interact_175_150 Characterization of the solution structure of a neuroligin\/beta-neurexin complex
Correia_2008_J.Mol.Biol_379_64 Crystal structure of a cellulosomal family 3 carbohydrate esterase from Clostridium thermocellum provides insights into the mechanism of substrate recognition
Costa_2008_Appl.Spectrosc_62_932 Following multi-component reactions in liquid medium using spectral band-fitting techniques
Crestani_2008_Rev.Laryngol.Otol.Rhinol.(Bord)_129_141 [Myasthenia gravis and oropharyngeal disorders: two cases reports]
Csermely_2008_Curr.Med.Chem_15_2401 Analysis of pyridinium aldoximes - a chromatographic approach
Cummings_2008_Alzheimers.Dement_4_49 Behavioral effects of current Alzheimer's disease treatments: a descriptive review
Dabisch_2008_Cutan.Ocul.Toxicol_27_123 Gender difference in the miotic potency of soman vapor in rats
Dai_2008_Zhongguo.Yi.Xue.Ke.Xue.Yuan.Xue.Bao_30_460 [Resection of centrally located primary liver cancer]
Damasio_2008_Aquat.Toxicol_87_310 Combined use of Daphnia magna in situ bioassays, biomarkers and biological indices to diagnose and identify environmental pressures on invertebrate communities in two Mediterranean urbanized and industrialized rivers (NE Spain)
De Jaco_2008_Chem.Biol.Interact_175_349 Trafficking of cholinesterases and neuroligins mutant proteins. An association with autism
De Lima_2008_Genet.Mol.Res_7_806 Effects of immature cashew nut-shell liquid (Anacardium occidentale) against oxidative damage in Saccharomyces cerevisiae and inhibition of acetylcholinesterase activity
de Oliveira_2008_Clin.Hemorheol.Microcirc_39_363 Modulation of erythrocyte deformability by PKC activity
DeSantis_2008_Mini.Rev.Med.Chem_8_619 Endothelial Lipase: a key player in HDL metabolism modulates inflammation and atherosclerotic risk
Devkota_2008_Nat.Prod.Rep_25_612 Terpenoid alkaloids of the Buxaceae family with potential biological importance
Dinamarca_2008_Chem.Biol.Interact_175_142 Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
Doctor_2008_Chem.Biol.Interact_175_1 The IXth International Meeting on Cholinesterases, Suzhou, People's Republic of China, 6 to 10 May 2007
Doupis_2008_Adv.Ther_25_627 DPP4 inhibitors: a new approach in diabetes treatment
Dubois_2008_Bull.Acad.Natl.Med_192_333 [Alzheimer's disease: therapeutic perspectives]
Durieux_2008_Acta.Chir.Belg_108_102 Extended transsternal thymectomy for myasthenia gravis: a report of 19 consecutive cases
Dyer_2008_BMJ_336_1035 Appeal Court rules that NICE procedure was unfair
Elshatory_2008_J.Neurosci_28_3291 The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons
Espallergues_2008_Chem.Biol.Interact_175_131 Hyposensitivity to the amnesic effects of scopolamine or amyloid beta(25-35) peptide in heterozygous acetylcholinesterase knockout (AChE(+\/-)) mice
Evoli_2008_Ann.N.Y.Acad.Sci_1132_76 Response to therapy in myasthenia gravis with anti-MuSK antibodies
Fain_2008_Metabolism_57_1005 Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue
Farahmand_2008_Circulation_118_S130 Skeletal myoblasts preserve remote matrix architecture and global function when implanted early or late after coronary ligation into infarcted or remote myocardium
Farid_2008_Toxicol.Lett_180_33 Gastrointestinal nematode infection increases organophosphate toxicity in rats
Fatima_2008_Arch.Pharm.Res_31_999 New butyrylcholinesterase inhibitory steroid and peroxy acid from Leucas urticifolia
Fernandez_2008_Am.J.Physiol.Endocrinol.Metab_295_E179 Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise
Fernandez-Gomez_2008_Chem.Biol.Interact_175_332 The level of butyrylcholinesterase activity increases and the content of the mRNA remains unaffected in brain of senescence-accelerated mouse SAMP8
Ferrero_2008_Expert.Rev.Neurother_8_979 Myasthenia gravis during pregnancy
Fex_2008_Biochem.Soc.Trans_36_885 Lipases in the pancreatic beta-cell: implications for insulin secretion
Figiel_2008_Prim.Care.Companion.J.Clin.Psychiatry_10_291 Safety and efficacy of rivastigmine in patients with Alzheimer's disease not responding adequately to donepezil: an open-label study
Fisher_2008_Neurotherapeutics_5_433 Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease
FitzGerald_2008_Cogn.Behav.Neurol_21_57 Effects of donepezil on verbal memory after semantic processing in healthy older adults
Flatt_2008_Front.Biosci_13_3648 Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes
Fluxa_2008_Nat.Protoc_3_1270 Enzyme assay and activity fingerprinting of hydrolases with the red-chromogenic adrenaline test
Forette_2008_Bull.Acad.Natl.Med_192_363 [Alzheimer's disease: from brain lesions to new drugs]
Foroutan_2008_Indian.J.Gastroenterol_27_62 Comparison of botulinium toxin injection and posterior anorectal myectomy in treatment of internal anal sphincter achalasia
Forssmann_2008_J.Immunol_181_1120 Inhibition of CD26\/dipeptidyl peptidase IV enhances CCL11\/eotaxin-mediated recruitment of eosinophils in vivo
Fujii_2008_Am.J.Nephrol_28_974 Putative role of endothelial lipase in dialysis patients with hypoalbuminemia and inflammation
Fukushima_2008_Chem.Pharm.Bull.(Tokyo)_56_1110 Synthesis and structure-activity relationships of potent 1-(2-substituted-aminoacetyl)-4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
Gajsek_2008_Chem.Biol.Interact_175_50 Synaptogenetic mechanisms controlling postsynaptic differentiation of the neuromuscular junction are nerve-dependent in human and nerve-independent in mouse C2C12 muscle cultures
Gao_2008_Chem.Biol.Interact_175_83 An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties
Garcia-Ayllon_2008_Chem.Biol.Interact_175_209 Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid
Gautier_2008_Diabetes.Metab_34 Suppl 2_S65 Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes
Geyer_2008_Chem.Biol.Interact_175_376 Increased organophosphate scavenging in a butyrylcholinesterase mutant
Ghadamyari_2008_J.Econ.Entomol_101_1432 Oxydemeton-methyl resistance, mechanisms, and associated fitness cost in green peach aphids (Hemiptera: Aphididae)
Ghadimi_2008_J.Enzyme.Inhib.Med.Chem_23_556 Structure-activity study of phosphoramido acid esters as acetylcholinesterase inhibitors
Gholivand_2008_Z.Naturforsch.C_63_241 Some new carbacylamidophosphates as inhibitors of acetylcholinesterase and butyrylcholinesterase
Ghosh_2008_J.Indian.Med.Assoc_106_373 Incretin based therapies for type 2 diabetes mellitus
Golomb_2008_Proc.Natl.Acad.Sci.U.S.A_105_E53 Reply to Blazer et al.: flawed challenges to Acetylcholinesterase inhibitors and Gulf War illnesses
Gomez_2008_Endocr.Metab.Immune.Disord.Drug.Targets_8_143 Growth hormone and insulin-like growth factor-I as an endocrine axis in Alzheimer's disease
Goscinski_2008_Oncology_75_49 Seprase, dipeptidyl peptidase IV and urokinase-type plasminogen activator expression in dysplasia and invasive squamous cell carcinoma of the esophagus. A study of 229 cases from Anyang Tumor Hospital, Henan Province, China
Graham_2008_Am.Fam.Physician_77_1173 AAFP and ACP release guideline on dementia treatment
Grossberg_2008_Drugs.Aging_25_573 Impact of rivastigmine on caregiver burden associated with Alzheimer's disease in both informal care and nursing home settings
Gschwendtner_2008_Stroke_39_1593 Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans
Haider_2008_Appl.Biochem.Biotechnol_144_225 Artificial neural network-genetic algorithm approach to optimize media constituents for enhancing lipase production by a soil microorganism
Haigh_2008_Chem.Biol.Interact_175_380 Protection of red blood cell acetylcholinesterase by oral huperzine A against ex vivo soman exposure: next generation prophylaxis and sequestering of acetylcholinesterase over butyrylcholinesterase
Haigh_2008_Chem.Biol.Interact_175_417 Advantages of the WRAIR whole blood cholinesterase assay: comparative analysis to the micro-Ellman, Test-mate ChE, and Michel (DeltapH) assays
Halimi_2008_Vasc.Health.Risk.Manag_4_481 Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet
Hansen_2008_Clin.Interv.Aging_3_211 Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis
Hasegawa_2008_BMC.Dev.Biol_8_71 The PPARgamma-selective ligand BRL-49653 differentially regulates the fate choices of rat calvaria versus rat bone marrow stromal cell populations
Hatfield_2008_Expert.Opin.Drug.Metab.Toxicol_4_1153 Modifications of human carboxylesterase for improved prodrug activation
Hazarika_2008_Clin.Cancer.Res_14_5325 Tasigna for chronic and accelerated phase Philadelphia chromosome--positive chronic myelogenous leukemia resistant to or intolerant of imatinib
He_2008_Sheng.Wu.Gong.Cheng.Xue.Bao_24_821 [Cutinase production from short-chain organic acids by Thermobifida fusca]
He_2008_Zhongguo.Zhong.Yao.Za.Zhi_33_813 [Inhibitory effects of sinapine on activity of acetylcholinesterase in cerebral homogenate and blood serum of rats]
Heravi_2008_Pak.J.Biol.Sci_11_740 Isolation and identification of a lipase producing Bacillus sp. from soil
Hernandez_2008_Inhal.Toxicol_20_839 Low level of exposure to pesticides leads to lung dysfunction in occupationally exposed subjects
Hildebrandt_2008_Talanta_75_1208 Development of a portable biosensor for screening neurotoxic agents in water samples
Hines_2008_J.Neurosci_28_6055 Synaptic imbalance, stereotypies, and impaired social interactions in mice with altered neuroligin 2 expression
Hitsumoto_2008_J.Atheroscler.Thromb_15_138 Effect of the angiotensin II receptor antagonist telmisartan on lipoprotein lipase mass in preheparin serum
Hoguet_2008_J.Environ.Sci.Health.B_43_465 Baseline activities of four biomarkers in three life-stages of the amphipod, Leptocheirus plumulosus
Hooper_2008_Clin.Chim.Acta_398_152 A novel missense LIPA gene mutation, N98S, in a patient with cholesteryl ester storage disease
Horton_2008_Endocr.Pract_14_625 Can newer therapies delay the progression of type 2 diabetes mellitus?
Hosseini_2008_Indian.J.Gastroenterol_27_99 Role of rectal biopsy in predicting response to intrasphincteric botulinum toxin injection for obstructive symptoms after a pullthrough operation
Hrobak_2008_AANA.J_76_95 Nerve agents: implications for anesthesia providers
Hsieh_2008_Anal.Chim.Acta_623_157 Assays for serum cholinesterase activity by capillary electrophoresis and an amperometric flow injection choline biosensor
Hu_2008_Respirology_13_837 Association between polymorphisms of microsomal epoxide hydrolase and COPD: results from meta-analyses
Hu_2008_Zhongguo.Zhong.Yao.Za.Zhi_33_1183 [Effect of Qingxin Kaiqiao fang on learning and memory ability and morphology of hippocampal nerve cells in AD mice]
Huang_2008_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_25_443 [The -384A >C polymorphism of endothelial lipase gene promoter region in Chinese healthy normolipidemic and endogenous hypertriglyceridemic subjects]
Huang_2008_Sheng.Wu.Gong.Cheng.Xue.Bao_24_445 [Directed evolution of lipase of Bacillus pumilus YZ02 by error-prone PCR]
Huang_2008_Z.Naturforsch.C_63_297 Lipase-catalyzed biodiesel production with methyl acetate as acyl acceptor
Huang_2008_Curr.Opin.Neurobiol_18_77 GABA and neuroligin signaling: linking synaptic activity and adhesion in inhibitory synapse development
Huisamen_2008_Cardiovasc.J.Afr_19_77 Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia
Hwang_2008_Mar.Biotechnol.(NY)_10_366 Screening enantioselective epoxide hydrolase activities from marine microorganisms: detection of activities in Erythrobacter spp
Inoue_2008_Clin.Toxicol.(Phila)_46_528 Prognostic factors and toxicokinetics in acute fenitrothion self-poisoning requiring intensive care
Iseki_2008_Chudoku.Kenkyu_21_151 [Antidose therapy for organophosphate poisoning]
Ito_2008_PPAR.Res_2008_759716 PPARalpha- and DEHP-Induced Cancers
Jett_2008_Chem.Biol.Interact_175_22 Cholinesterase research at the National Institutes of Health, USA
Jogani_2008_Alzheimer.Dis.Assoc.Disord_22_116 Intranasal mucoadhesive microemulsion of tacrine to improve brain targeting
Jones_2008_Alzheimers.Dement_4_145 The Atorvastatin\/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics
Josif_2008_JAAPA_21_22 Diagnosis and treatment of dementia with Lewy bodies
Jun_2008_Chem.Biol.Interact_175_421 Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro
Kamahori_2008_Anal.Sci_24_1073 Enzyme immunoassay using a reusable extended-gate field-effect-transistor sensor with a ferrocenylalkanethiol-modified gold electrode
Kaneko_2008_Nihon.Shinkei.Seishin.Yakurigaku.Zasshi_28_63 [Neuronal migration in the adult brain]
Kang_2008_J.Microbiol.Biotechnol_18_1427 Identification of proteins binding to decursinol by chemical proteomics
Kasai_2008_Jpn.J.Infect.Dis_61_184 PCR-based identification of Culex pipiens complex collected in Japan
Kasana_2008_J.Basic.Microbiol_48_207 Isolation and identification of a psychrotrophic Acinetobacter sp. CR9 and characterization of its alkaline lipase
Kato_2008_Scand.J.Gastroenterol_43_1018 Reduced hepatic expression of adipose tissue triglyceride lipase and CGI-58 may contribute to the development of non-alcoholic fatty liver disease in patients with insulin resistance
Kayrak_2008_Am.J.Health.Syst.Pharm_65_1051 Complete atrioventricular block associated with rivastigmine therapy
Kobayashi_2008_J.Med.Food_11_289 Inhibitory effect of Myrica bark on lipase activity in mouse plasma and gastrointestinal tract
Kocelak_2008_J.Gastroenterol_43_609 Long-term effects of lipase inhibition by orlistat on gastric emptying and orocecal transit time of a solid meal
Koehnke_2008_Structure_16_410 Crystal structures of beta-neurexin 1 and beta-neurexin 2 ectodomains and dynamics of splice insertion sequence 4
Koladiya_2008_BMC.Pharmacol_8_14 Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats
Korczyn_2008_Alzheimers.Dement_4_371 Treatment of advanced Alzheimer's disease with cholinesterase inhibitors
Kotani_2008_Chem.Biol.Interact_175_227 Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis
Kourist_2008_Chembiochem_9_491 Enzymatic synthesis of optically active tertiary alcohols: expanding the biocatalysis toolbox
Koyama_2008_Chudoku.Kenkyu_21_145 [Kinetics of organophorus pesticides]
Kucukkilinc_2008_Chem.Biol.Interact_175_309 Inhibition of electric eel acetylcholinesterase by triarylmethane dyes
Kuhad_2008_Life.Sci_83_128 Lycopene attenuates diabetes-associated cognitive decline in rats
Kuroki_2008_Pancreas_37_203 Culture of porcine fetal pancreatic neurons
Lakshmi_2008_Singapore.Med.J_49_561 Serum cholinesterases in Down syndrome children before and after nutritional supplementation
Lalli_2008_Expert.Rev.Neurother_8_1181 Rivastigmine in Parkinson's disease dementia
Lawson-Yuen_2008_Eur.J.Hum.Genet_16_614 Familial deletion within NLGN4 associated with autism and Tourette syndrome
Lee_2008_Pest.Manag.Sci_64_544 Host perception and signal transduction studies in wild-type Blumeria graminis f. sp. hordei and a quinoxyfen-resistant mutant implicate quinoxyfen in the inhibition of serine esterase activity
Li_2008_Fish.Physiol.Biochem_34_209 Acute toxicity of the pesticide methomyl on the topmouth gudgeon (Pseudorasbora parva): mortality and effects on four biomarkers
Li_2008_Chem.Biol.Interact_175_68 Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase
Lin_2008_Chem.Biol.Interact_175_352 Anti-acetylcholinesterase activities of traditional Chinese medicine for treating Alzheimer's disease
Liu_2008_J.Clin.Endocrinol.Metab_93_1980 Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men
Locca_2008_J.Am.Med.Dir.Assoc_9_439 Pharmacological treatment of behavioral and psychological symptoms of dementia (BPSD) in nursing homes: development of practice recommendations in a Swiss canton
Lopez-Munoz_2008_Rev.Neurol_47_99 [The development of neurotoxic agents as chemical weapons during the National Socialist period in Germany]
Lu_2008_Cell.Host.Microbe_4_293 Host inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection
Luo_2008_Chem.Biol.Interact_175_261 Comparison of oxime reactivation and aging of nerve agent-inhibited monkey and human acetylcholinesterases
Madsbad_2008_Curr.Opin.Clin.Nutr.Metab.Care_11_491 Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials
Maingrette_2008_J.Lipid.Res_49_1926 C-reactive protein enhances macrophage lipoprotein lipase expression
Man_2008_J.Alzheimers.Dis_14_209 Systematic review on the efficacy and safety of herbal medicines for Alzheimer's disease
Mancini_2008_Vasc.Health.Risk.Manag_4_325 Orlistat in the prevention of diabetes in the obese patient
Marino_2008_Diabetes.Self.Manag_25_60, 62 DPP-4 inhibitors. A new class of drugs for type 2 diabetes
Martin_2008_Diabetes.Educ_34 Suppl 3_66S Beyond glycemic control: the effects of incretin hormones in type 2 diabetes
Masilamoni_2008_Free.Radic.Res_42_661 The neuroprotective role of melatonin against amyloid beta peptide injected mice
Masson_2008_Chem.Biol.Interact_175_273 A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters
Massoulie_2008_Chem.Biol.Interact_175_30 Old and new questions about cholinesterases
Mastrantonio_2008_J.Mol.Model_14_813 Interpretation of the mechanism of acetylcholinesterase inhibition ability by organophosphorus compounds through a new conformational descriptor. an experimental and theoretical study
Mathurin_2008_Acta.Gastroenterol.Latinoam_38_116 [Renal failure in patients with cirrhosis and ascites: incidence, etiology and predictive factors]
Matsuo_2008_J.Oleo.Sci_57_375 Continuous synthesis of glyceryl ferulate using immobilized Candida antarctica lipase
McGeown_2008_Neuropsychiatr.Dis.Treat_4_465 Prolonged cholinergic enrichment influences regional cortical activation in early Alzheimer's disease
Meier-Ruge_2008_Pathobiology_75_233 Current concepts of enzyme histochemistry in modern pathology
Modrego_2008_Am.J.Alzheimers.Dis.Other.Demen_23_286 The clinical significance of plasmatic amyloid A{beta}-40 peptide levels in Alzheimer's disease patients treated with galantamine
Mohammad_2008_Arh.Hig.Rada.Toksikol_59_145 Acute toxicity and cholinesterase inhibition in chicks dosed orally with organophosphate insecticides
Moral-Naranjo_2008_Chem.Biol.Interact_175_312 Targeting of acetylcholinesterase to lipid rafts of muscle
Morita_2008_J.Oleo.Sci_57_557 Efficient production of di- and tri-acylated mannosylerythritol lipids as glycolipid biosurfactants by Pseudozyma parantarctica JCM 11752(T)
Mucha_2008_J.Manag.Care.Pharm_14_451 Comparison of cholinesterase inhibitor utilization patterns and associated health care costs in Alzheimer's disease
Naik_2008_Chem.Biol.Interact_175_298 Comparison of methods used for the determination of cholinesterase activity in whole blood
Nakahata_2008_Anesthesiology_109_124 Cholinesterase inhibitor donepezil dilates cerebral parenchymal arterioles via the activation of neuronal nitric oxide synthase
Nakao_2008_J.Oleo.Sci_57_371 Enzymatic synthesis of astaxanthin n-octanoic acid esters
Namera_2008_Chudoku.Kenkyu_21_141 [Simple detection of organophosphates in biological materials]
Nezhinskaia_2008_Eksp.Klin.Farmakol_71_65 [Modulation of the cholinergic system during inflammation]
Niederhofer_2008_Drugs.Aging_25_715 Acetylcholinesterase inhibitors may improve efficacy and reduce adverse effects of tricyclic antidepressants for depression
Nong_2008_J.Toxicol.Environ.Health.A_71_1363 Bayesian calibration of a physiologically based pharmacokinetic\/pharmacodynamic model of carbaryl cholinesterase inhibition
Novakovic_2008_Acta.Crystallogr.C_64_o502 Weak intermolecular interactions in 11-chloro-2,3,4,5-tetrahydro-1H-cyclohepta[b]quinoline
Ogawa_2008_Biol.Pharm.Bull_31_1059 Exosome-like vesicles with dipeptidyl peptidase IV in human saliva
Oh_2008_Chem.Biol.Interact_175_365 Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes
Ohsone_2008_Masui_57_838 [Reversal of neuromuscular blockade and complications of remaining blocking effect]
Onoue_2008_Gan.To.Kagaku.Ryoho_35_1080 [Role of UGT1A1*28 and UGT1A1*6 for irinotecan-induced adverse drug reaction]
Pages_2008_Malar.J_7_178 Malaria transmission in Dakar: a two-year survey
Pagotto_2008_G.Ital.Cardiol.(Rome)_9_83S [Pharmacological therapy of obesity]
Pan_2008_Sheng.Wu.Gong.Cheng.Xue.Bao_24_673 [Expression of Candida antarctica lipase B on yeast surface and synthesis of ethyl hexanoate catalyzed by CALB]
Paraje_2008_Can.J.Microbiol_54_647 Candida albicans-secreted lipase induces injury and steatosis in immune and parenchymal cells
Pato_2008_Chem.Biol.Interact_175_64 Role of lipid rafts in agrin-elicited acetylcholine receptor clustering
Patocka_2008_Curr.Drug.Metab_9_332 Possible role of hydroxylated metabolites of tacrine in drug toxicity and therapy of Alzheimer's disease
Paulick_2008_Biochemistry_47_6991 The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins
Paz_2008_Biophys.J_95_1928 Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3
Pei_2008_Curr.Opin.Drug.Discov.Devel_11_512 From the bench to the bedside: dipeptidyl peptidase IV inhibitors, a new class of oral antihyperglycemic agents
Penco_2008_BMC.Bioinformatics_9_254 New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background
Penfornis_2008_Diabetes.Metab_34 Suppl 2_S78 Therapeutic approach of type 2 diabetes mellitus with GLP-1 based therapies
Perera_2008_Malar.J_7_168 Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka
Perera_2008_Hum.Exp.Toxicol_27_513 Comparison of two commonly practiced atropinization regimens in acute organophosphorus and carbamate poisoning, doubling doses vs. ad hoc: a prospective observational study
Peter_2008_Anaesth.Intensive.Care_36_339 Adjuncts and alternatives to oxime therapy in organophosphate poisoning--is there evidence of benefit in human poisoning? A review
Pibiri_2008_Proc.Natl.Acad.Sci.U.S.A_105_14169 The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice
Picco_2008_J.Environ.Sci.Health.B_43_405 Use of cholinesterase activity in monitoring chlorpyrifos exposure of steer cattle after topical administration
Pinent_2008_Genomics_92_26 Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice
Pi-Sunyer_2008_Postgrad.Med_120_5 The effects of pharmacologic agents for type 2 diabetes mellitus on body weight
Poewe_2008_Pract.Neurol_8_238 When a Parkinson's disease patient starts to hallucinate
Polizelli_2008_Appl.Biochem.Biotechnol_150_233 A new lipase isolated from oleaginous seeds from Pachira aquatica (Bombacaceae)
Poole_2008_Brain.Inj_22_519 Cholinomimetic agents and neurocognitive impairment following head injury: a systematic review
Pratley_2008_Medscape.J.Med_10_171 Overview of glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors for type 2 diabetes
Pratley_2008_Rev.Diabet.Stud_5_73 Targeting Incretins in Type 2 Diabetes: Role of GLP-1 Receptor Agonists and DPP-4 Inhibitors
Radchenko_2008_Dokl.Biochem.Biophys_418_47 Modeling of the relationships between the structure of O-phosphorylated oximes and their anticholinesterase activity and selectivity using molecular field topology analysis (MFTA)
Rajini_2008_J.Toxicol.Environ.Health.A_71_1043 A comparative study on the relationship between various toxicological endpoints in Caenorhabditis elegans exposed to organophosphorus insecticides
Reale_2008_J.Alzheimers.Dis_14_147 Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease
Rehiman_2008_JNMA.J.Nepal.Med.Assoc_47_47 Correlation of serum cholinesterase level, clinical score at presentation and severity of organophosphorous poisoning
Reis_2008_Langmuir_24_7400 Competition between lipases and monoglycerides at interfaces
Reis_2008_Langmuir_24_6812 Lipases at interfaces: unique interfacial properties as globular proteins
Rezg_2008_C.R.Biol_331_655 Biochemical evaluation of hepatic damage in subchronic exposure to malathion in rats: effect on superoxide dismutase and catalase activities using native PAGE
Rotundo_2008_Chem.Biol.Interact_175_26 Assembly and regulation of acetylcholinesterase at the vertebrate neuromuscular junction
Rozengart_2008_Dokl.Biochem.Biophys_419_82 A comparative study of antichymotryptic and anticholinesterase activity of organophosphorus quasi-substrate inhibitors
Rozengart_2008_Zh.Evol.Biokhim.Fiziol_44_12 [Thiosubstrates of different cholinesterases]
Saiki_2008_Metabolism_57_1093 Suppression of lipoprotein lipase expression in 3T3-L1 cells by inhibition of adipogenic differentiation through activation of the renin-angiotensin system
Saisubramanian_2008_Appl.Biochem.Biotechnol_150_139 Two step purification of Acinetobacter sp. lipase and its evaluation as a detergent additive at low temperatures
Sakai_2008_J.Biosci.Bioeng_105_687 Transesterification by lipase entrapped in electrospun poly(vinyl alcohol) fibers and its application to a flow-through reactor
Sakakibara_2008_Carbohydr.Res_343_2740 A facile synthesis of 4,6-O-benzylidene-D-glycals via 1,5-anhydro-4,6-O-benzylidene-D-hex-1-en-3-ulose
Sakayama_2008_Anticancer.Res_28_2081 The synthesis and activity of lipoprotein lipase in the subcutaneous adipose tissue of patients with musculoskeletal sarcomas
Samarawickrema_2008_Clin.Toxicol.(Phila)_46_489 Fetal effects of environmental exposure of pregnant women to organophosphorus compounds in a rural farming community in Sri Lanka
Santos_2008_J.Phys.Chem.B_112_3581 Orientation of cutinase adsorbed onto PMMA nanoparticles probed by tryptophan fluorescence
Sattigeri_2008_Bioorg.Med.Chem.Lett_18_4087 Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors
Savage_2008_J.Med.Entomol_45_276 Host-seeking heights, host-seeking activity patterns, and West Nile virus infection rates for members of the Culex pipiens complex at different habitat types within the hybrid zone, Shelby County, TN, 2002 (Diptera: Culicidae)
Saxena_2008_Chem.Biol.Interact_175_267 Efficacy of human serum butyrylcholinesterase against sarin vapor
Schmidt_2008_Clin.Nucl.Med_33_398 Value of combining activated brain FDG-PET and cardiac MIBG for the differential diagnosis of dementia: differentiation of dementia with Lewy bodies and Alzheimer disease when the diagnoses based on clinical and neuroimaging criteria are difficult
Secundo_2008_Biotechnol.Bioeng_101_255 Role of methoxypolyethylene glycol on the hydration, activity, conformation and dynamic properties of a lipase in a dry film
Semba_2008_Biosci.Biotechnol.Biochem_72_1457 Expression of hydroxynitrile lyase from Manihot esculenta in yeast and its application in (S)-mandelonitrile production using an immobilized enzyme reactor
Semba_2008_Appl.Microbiol.Biotechnol_79_563 Efficient production of active form of recombinant cassava hydroxynitrile lyase using Escherichia coli in low-temperature culture
Serra_2008_Int.J.Clin.Pharmacol.Ther_46_349 Evaluation of pharmacokinetic and pharmacodynamic interaction between the dipeptidyl peptidase IV inhibitor vildagliptin, glyburide and pioglitazone in patients with Type 2 diabetes
Shafferman_2008_Chem.Biol.Interact_175_166 Flexibility versus rigidity of the functional architecture of AChE active center
Shen_2008_Structure_16_422 Regulation of neurexin 1beta tertiary structure and ligand binding through alternative splicing
Shimohama_2008_Nihon.Yakurigaku.Zasshi_131_351 [Treatment of Alzheimer's disease: status quo and future considerations]
Silman_2008_Chem.Biol.Interact_175_3 Acetylcholinesterase: how is structure related to function?
Slotkin_2008_Brain.Res.Bull_76_424 Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro
Song_2008_Zhongguo.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_20_558 [Changes in plasma endotoxin content due to cholinesterase inhibitor VX intoxication and therapeutic effect of benthiaczine in mice]
Song_2008_Cancer.Res_68_4693 Activated cholinergic signaling provides a target in squamous cell lung carcinoma
Sperling_2008_Chem.Biol.Interact_175_156 Characterisation of cholinesterase expression during murine embryonic stem cell differentiation
Starner_2008_J.Manag.Care.Pharm_14_462 Cholinesterase inhibitor utilization patterns: just because it can be counted does not mean it counts
Stiefelhagen_2008_MMW.Fortschr.Med_150_17 [Surprising etiology of chronic deglutition disorder. Diagnosis at a glance in dysphagia]
Stojan_2008_Chem.Biol.Interact_175_242 Kinetic evaluation of multiple initial rate data by simultaneous analysis with two equations
Su_2008_Chem.Biol.Interact_175_101 A monoclonal antibody against synaptic AChE: a useful tool for detecting apoptotic cells
Sugimoto_2008_Chem.Biol.Interact_175_204 The new approach in development of anti-Alzheimer's disease drugs via the cholinergic hypothesis
Sugimoto_2008_Nihon.Yakurigaku.Zasshi_131_338 [New approaches for the development of anti-Alzheimer's disease drugs based on the cholinergic hypothesis and amyloid hypothesis]
Sun_2008_Chem.Biol.Interact_175_428 Long-term effects of human butyrylcholinesterase pretreatment followed by acute soman challenge in cynomolgus monkeys
Sussman_2008_Ann.N.Y.Acad.Sci_1132_283 Antisense treatment for myasthenia gravis: experience with monarsen
Swanson_2008_J.Hand.Surg.Am_33_1093 Comparison of neurotization versus nerve repair in an animal model of chronically denervated muscle
Takayama_2008_Chudoku.Kenkyu_21_123 [History of insecticides and the transition of their production and sales]
Tan_2008_Lab.Chip_8_885 A lab-on-a-chip for detection of nerve agent sarin in blood
Thomas_2008_J.Pharmacol.Exp.Ther_325_175 (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylm ethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors
Thongtang_2008_J.Med.Assoc.Thai_91_943 Incretins: the novel therapy of type 2 diabetes
Toiber_2008_PLoS.One_3_e3108 N-acetylcholinesterase-induced apoptosis in Alzheimer's disease
Trinkaus_2008_Chem.Biol.Interact_175_45 Reciprocal neural regulation of extrajunctional acetylcholinesterase and collagen Q in rat muscles--the role of calcineurin signaling
Tsim_2008_Chem.Biol.Interact_175_58 Transcriptional control of different subunits of AChE in muscles: signals triggered by the motor nerve-derived factors
Ueatrongchit_2008_Biosci.Biotechnol.Biochem_72_1513 Purification and characterization of a novel (R)-hydroxynitrile lyase from Eriobotrya japonica (Loquat)
Valle_2008_Chem.Biol.Interact_175_343 The cholinesterases: analysis by pharmacogenomics in man
van Marum_2008_Fundam.Clin.Pharmacol_22_265 Current and future therapy in Alzheimer's disease
Varma_2008_Appl.Biochem.Biotechnol_144_213 Effect of chain length on enzymatic hydrolysis of p-nitrophenyl esters in supercritical carbon dioxide
Vidal_2008_Alzheimer.Dis.Assoc.Disord_22_125 Memantine therapy for Alzheimer disease in real-world practice: an observational study in a large representative sample of French patients
Vidinha_2008_J.Biotechnol_135_181 Probing the microenvironment of sol-gel entrapped cutinase: the role of added zeolite NaY
Vieira_2008_An.Acad.Bras.Cienc_80_419 Two fast screening methods (GC-MS and TLC-ChEI assay) for rapid evaluation of potential anticholinesterasic indole alkaloids in complex mixtures
Vignaud_2008_Chem.Biol.Interact_175_129 Genetic ablation of acetylcholinesterase alters muscle function in mice
Vinokurova_2008_Ter.Arkh_80_75 [The role of neuromediators and cytokines in pathogenesis of chronic pancreatitis of alcohol etiology]
von Langermann_2008_Bioprocess.Biosyst.Eng_31_155 Hydroxynitrile lyase catalyzed cyanohydrin synthesis at high pH-values
Wanekaya_2008_J.Environ.Monit_10_703 Recent biosensing developments in environmental security
Wang_2008_Environ.Sci.Technol_42_2688 Carbon nanotube-based electrochemical sensor for assay of salivary cholinesterase enzyme activity: an exposure biomarker of organophosphate pesticides and nerve agents
Wang_2008_Neurotox.Res_13_163 Protective effects of N-methyl-D-aspartate receptor antagonism on VX-induced neuronal cell death in cultured rat cortical neurons
Wardle_2008_Curr.Med.Chem_15_2230 Organophosphorus compounds: intervention in mechanisms of signal transduction relevant to proliferative, immunological and circulatory disorders
Watt_2008_Biochem.J_414_313 Regulation and function of triacylglycerol lipases in cellular metabolism
Wattmo_2008_Dement.Geriatr.Cogn.Disord_26_203 Predicting long-term cognitive outcome with new regression models in donepezil-treated Alzheimer patients in a naturalistic setting
Weinreb_2008_Front.Biosci_13_5131 The neuroprotective mechanism of action of the multimodal drug ladostigil
Weinreb_2008_Chem.Biol.Interact_175_318 The neuroprotective effect of ladostigil against hydrogen peroxide-mediated cytotoxicity
Weismuller_2008_Scand.J.Gastroenterol_43_736 Prediction of survival after liver transplantation by pre-transplant parameters
Wermter_2008_Am.J.Med.Genet.B.Neuropsychiatr.Genet_147B_535 No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning level
Weschules_2008_J.Palliat.Med_11_738 Acetylcholinesterase inhibitor and N-methyl-D-aspartic acid receptor antagonist use among hospice enrollees with a primary diagnosis of dementia
Whyte_2008_Cerebrovasc.Dis_26_317 An open-label pilot study of acetylcholinesterase inhibitors to promote functional recovery in elderly cognitively impaired stroke patients
Wood_2008_Appl.Physiol.Nutr.Metab_33_761 Interactions between hepatic lipase and apolipoprotein E gene polymorphisms affect serum lipid profiles of healthy Canadian adults
Wrenger_2008_Front.Biosci_13_3194 Non-substrate peptides influencing dipeptidyl peptidase IV\/CD26 activity and immune cell function
Wu_2008_Chem.Biol.Interact_175_403 Synthesis of Drosophila melanogaster acetylcholinesterase gene using yeast preferred codons and its expression in Pichia pastoris
Wu_2008_Lipids_43_733 Hepatic lipase gene -514C\/T polymorphism in the Guangxi Hei Yi Zhuang and Han populations
Xie_2008_Chem.Biol.Interact_175_79 The promoter activity of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in muscle: suppressive roles of myogenesis and innervating nerve
Yazbeck_2008_Front.Biosci_13_6850 Inhibiting dipeptidyl peptidase activity partially ameliorates colitis in mice
Yoshida_2008_Yakugaku.Zasshi_128_851 [Preparedness response to hazard and toxic incidents and food terrorism]
Yu_2008_J.Biosci.Bioeng_106_65 Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups
Zahodne_2008_Drugs.Aging_25_665 Pathophysiology and treatment of psychosis in Parkinson's disease: a review
Zeljezic_2008_Basic.Clin.Pharmacol.Toxicol_103_329 Cholinesterase-inhibiting and genotoxic effects of acute carbofuran intoxication in man: a case report
Zhan_2008_Zhonghua.Gan.Zang.Bing.Za.Zhi_16_375 [Association of hepatic lipase gene promoter polymorphism -514C\/T with nonalcoholic fatty liver disease]
Zhang_2008_Chem.Biol.Interact_175_396 Potential therapeutic targets of huperzine A for Alzheimer's disease and vascular dementia
Zhang_2008_J.Environ.Sci.(China)_20_364 Influences of Cu or Cd on the neurotoxicity induced by petroleum hydrocarbons in ragworm Perinereis aibuhitensis
Zhang_2008_Zhongguo.Zhong.Xi.Yi.Jie.He.Za.Zhi_28_529 [Effect and mechanism of jiannao yizhi decoction on learning and memory in rats with similar Alzheimer's disease]
Zhang_2008_Toxicology_248_136 Permethrin may induce adult male mouse reproductive toxicity due to cis isomer not trans isomer
Zhong_2008_Alzheimers.Dement_4_179 Apolipoprotein E4 domain interaction: synaptic and cognitive deficits in mice
Zhu_2008_Talanta_74_1579 Quantitative analysis of hydrolysis of carbaryl in tap water and river by excitation-emission matrix fluorescence coupled with second-order calibration
Zhu_2008_Yao.Xue.Xue.Bao_43_267 Construction of the pharmacophore model of acetylcholinesterase inhibitor
Zinman_2008_Ann.N.Y.Acad.Sci_1132_264 IVIG treatment for myasthenia gravis: effectiveness, limitations, and novel therapeutic strategies
Zivin_2008_Psychiatr.Danub_20_168 Prolonged treatment with donepezil increases acetylcholinesterase expression in the central nervous system
Abdel_2008_Neurotoxicol_29_833 Effects of occupational pesticide exposure on children applying pesticides
Abe_2008_Neuropharmacol_55_1419 Involvement of dopamine D2 receptors in the induction of long-term potentiation in the basolateral amygdala-dentate gyrus pathway of anesthetized rats
Aboody_2008_Gene.Ther_15_739 Stem and progenitor cell-mediated tumor selective gene therapy
Adamec_2008_Behav.Brain.Res_189_180 The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice
Agrawal_2008_Behav.Brain.Res_189_381 Effect of insulin and melatonin on acetylcholinesterase activity in the brain of amnesic mice
Ahren_2008_Expert.Opin.Emerg.Drugs_13_593 Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetes
Ajami_2008_FEBS.Lett_582_819 Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8
Aker_2008_Environ.Toxicol_23_548 Comparing the relative toxicity of malathion and malaoxon in blue catfish Ictalurus furcatus
Akhondzadeh_2008_Prog.Neuropsychopharmacol.Biol.Psychiatry_32_1810 A 12-week, double-blind, placebo-controlled trial of donepezil adjunctive treatment to risperidone in chronic and stable schizophrenia
Alarcon_2008_Z.Naturforsch.C_63_853 Inhibition of acetylcholinesterase activity by dihydro-beta-agarofuran sesquiterpenes isolated from Chilean Celastraceae
Alexander_2008_Gene.Ther_15_831 Potential of AAV vectors in the treatment of metabolic disease
Ali_2008_Chemosphere_71_1823 Genotoxicity assessment of acute exposure of chlorpyrifos to freshwater fish Channa punctatus (Bloch) using micronucleus assay and alkaline single-cell gel electrophoresis
Ali_2008_Environ.Mol.Mutagen_49_374 Cytogenetic damage in female Pakistani agricultural workers exposed to pesticides
Alloue_2008_Appl.Biochem.Biotechnol_150_51 Comparison of Yarrowia lipolytica lipase immobilization yield of entrapment, adsorption, and covalent bond techniques
Al-Masri_2008_ChemMedChem_3_1763 Discovery of DPP IV inhibitors by pharmacophore modeling and QSAR analysis followed by in silico screening
Almeida_2008_Clin.Hemorheol.Microcirc_40_99 Modulation of hemorheological parameters by the erythrocyte redox thiol status
Alonso-Vale_2008_J.Pineal.Res_45_422 Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes
Aloulou_2008_Cell.Mol.Life.Sci_65_851 Gastric lipase: an extremophilic interfacial enzyme with medical applications
Anand_2008_J.Insect.Physiol_54_1404 Age-dependent changes of fat body stores and the regulation of fat body lipid synthesis and mobilisation by adipokinetic hormone in the last larval instar of the cricket, Gryllus bimaculatus
Andre-Leroux_2008_Proteins_72_1298 Structure-based mutagenesis of Penicillium griseofulvum xylanase using computational design
Annuzzi_2008_Nutr.Metab.Cardiovasc.Dis_18_531 Postprandial chylomicrons and adipose tissue lipoprotein lipase are altered in type 2 diabetes independently of obesity and whole-body insulin resistance
Ansari_2008_Bioorg.Med.Chem_16_7691 Solid-phase synthesis and biological evaluation of a parallel library of 2,3-dihydro-1,5-benzothiazepines
Antonio-Garcia_2008_Food.Chem.Toxicol_46_2089 Toxic effects of perinatal lead exposure on the brain of rats: involvement of oxidative stress and the beneficial role of antioxidants
Arai_2008_J.Gerontol.A.Biol.Sci.Med.Sci_63_1209 Adipose endocrine function, insulin-like growth factor-1 axis, and exceptional survival beyond 100 years of age
Armenta_2008_Appl.Spectrosc_62_1322 A mid-infrared flow-through sensor for label-free monitoring of enzyme inhibition
Arrese_2008_Insect.Biochem.Mol.Biol_38_993 Expression of lipid storage droplet protein-1 may define the role of AKH as a lipid mobilizing hormone in Manduca sexta
Asea_2008_J.Reprod.Immunol_79_12 Heat shock protein-containing exosomes in mid-trimester amniotic fluids
Atzet_2008_Biomacromolecules_9_3370 Degradable poly(2-hydroxyethyl methacrylate)-co-polycaprolactone hydrogels for tissue engineering scaffolds
Avogaro_2008_G.Ital.Cardiol.(Rome)_9_753 [Glucagon-like peptide-1: pleiotropic effects on the cardiovascular system]
Baffi_2008_Mol.Biochem.Parasitol_160_70 Esterase enzymes involved in pyrethroid and organophosphate resistance in a Brazilian population of Riphicephallus (Boophilus) microplus (Acari, Ixodidae)
Baldassarre_2008_Transgenic.Res_17_863 Milk composition studies in transgenic goats expressing recombinant human butyrylcholinesterase in the mammary gland
Ballard_2008_Curr.Med.Res.Opin_24_2561 Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: the VantagE study
Balmayor_2008_J.Mater.Sci.Mater.Med_19_1617 A novel enzymatically-mediated drug delivery carrier for bone tissue engineering applications: combining biodegradable starch-based microparticles and differentiation agents
Barten_2008_Mol.Neurobiol_37_171 Therapeutic strategies for Alzheimer's disease
Bas_2008_Proteins_73_765 Very fast prediction and rationalization of pKa values for protein-ligand complexes
Bates_2008_J.Anim.Sci_86_3279 Differential expression in lung and bronchial lymph node of pigs with high and low responses to infection with porcine reproductive and respiratory syndrome virus
Beigneux_2008_J.Lipid.Res_49_1312 Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase
Beller_2008_PLoS.Biol_6_e292 COPI complex is a regulator of lipid homeostasis
Bello-Sani_2008_Ann.Afr.Med_7_88 Myasthenia gravis associated with autoimmune thyroid disease: a report of two patients
Ben Rebah_2008_Lett.Appl.Microbiol_47_549 Culture of Staphylococcus xylosus in fish processing by-product-based media for lipase production
Benabdallah_2008_Pharmacol.Res_57_132 The spontaneous mechanical activity of the circular smooth muscle of the rabbit colon in vitro
Bertoni_2008_Naunyn.Schmiedebergs.Arch.Pharmacol_378_335 In vitro and in vivo pharmacological analysis of imidazole-free histamine H3 receptor antagonists: promising results for a brain-penetrating H3 blocker with weak anticholinesterase activity
Beyer_2008_Curr.Med.Chem_15_2748 The therapeutical potential of alpha-synuclein antiaggregatory agents for dementia with Lewy bodies
Bhagwandin_2008_J.Chem.Neuroanat_35_371 Nuclear organization and morphology of cholinergic, putative catecholaminergic and serotonergic neurons in the brains of two species of African mole-rat
Bista_2008_Mol.Immunol_45_3618 Lymphocyte quiescence factor Dpp2 is transcriptionally activated by KLF2 and TOB1
Bloch-Shilderman_2008_Toxicol.Appl.Pharmacol_231_17 Subchronic exposure to low-doses of the nerve agent VX: physiological, behavioral, histopathological and neurochemical studies
Blum_2008_Biochemistry_47_5216 Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase
Bocchetti_2008_Mar.Environ.Res_66_24 Seasonal variations of exposure biomarkers, oxidative stress responses and cell damage in the clams, Tapes philippinarum, and mussels, Mytilus galloprovincialis, from Adriatic sea
Brenner_2008_J.Neuroimmunol_201-202_121 Acetylcholinesterase inhibitors and cholinergic modulation in Myasthenia Gravis and neuroinflammation
Brissos_2008_Biochim.Biophys.Acta_1784_1326 Biochemical and structural characterisation of cutinase mutants in the presence of the anionic surfactant AOT
Brito-Madurro_2008_Biochem.Genet_46_557 A single amino acid substitution in one of the lipases of Aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid
Bromberg_2008_Biochim.Biophys.Acta_1784_961 Kinetic study of the thermal inactivation of cholinesterase enzymes immobilized in solid matrices
Brown_2008_Neurosci_154_147 Dendrites of medial olivocochlear neurons in mouse
Burcelin_2008_Diabetes.Metab_34_627 What is known, new and controversial about GLP-1? Minutes of the 1st European GLP-1 Club Meeting, Marseille, 28-29 May 2008
Burkey_2008_Diabetes.Obes.Metab_10_1057 Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited
Buttemer_2008_Chemosphere_72_1315 Fenitrothion, an organophosphate, affects running endurance but not aerobic capacity in fat-tailed dunnarts (Sminthopsis crassicaudata)
Buznikov_2008_Neurotoxicol.Teratol_30_503 Amyloid precursor protein 96-110 and beta-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids
Byun_2008_Cancer.Lett_266_238 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1
Caimari_2008_Int.J.Obes.(Lond)_32_1193 Impairment of nutritional regulation of adipose triglyceride lipase expression with age
Campagna_2008_Biochem.Biophys.Res.Commun_377_843 Novel mutations in the adipose triglyceride lipase gene causing neutral lipid storage disease with myopathy
Camps_2008_J.Med.Chem_51_3588 Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation
Cantin_2008_J.Immunol.Methods_338_21 Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants
Carageorgiou_2008_Neuropsychiatr.Dis.Treat_4_687 The effects of rivastigmine plus selegiline on brain acetylcholinesterase, (Na, K)-, Mg-ATPase activities, antioxidant status, and learning performance of aged rats
Carr_2008_Toxicol.Sci_106_186 Effect of different administration paradigms on cholinesterase inhibition following repeated chlorpyrifos exposure in late preweanling rats
Carvalho_2008_Clin.Hemorheol.Microcirc_40_207 Non-neuronal cholinergic system and signal transduction pathways mediated by band 3 in red blood cells
Carvalho_2008_Appl.Biochem.Biotechnol_150_25 Sequential production of amylolytic and lipolytic enzymes by bacterium strain isolated from petroleum contaminated soil
Casanovas_2008_J.Proteome.Res_7_4173 Application of proteomic tools to detect the nonspecificity of a polyclonal antibody against lipoprotein lipase
Cellek_2008_Neurogastroenterol.Motil_20_539 Synergy between 5-HT4 receptor activation and acetylcholinesterase inhibition in human colon and rat forestomach
Chakra_2008_Ecotoxicol.Environ.Saf_71_574 Biological response of earthworm, Eisenia foetida (Savigny) to an organophosphorous pesticide, profenofos
Chakraborty_2008_J.Agric.Food.Chem_56_1428 Enrichment of eicosapentaenoic acid from sardine oil with Delta5-olefinic bond specific lipase from Bacillus licheniformis MTCC 6824
Chandrayan_2008_Protein.Expr.Purif_59_327 Expression, purification, refolding and characterization of a putative lysophospholipase from Pyrococcus furiosus: retention of structure and lipase\/esterase activity in the presence of water-miscible organic solvents at high temperatures
Charbonneau_2008_Curr.Med.Res.Opin_24_3287 A retrospective study of cholinesterase inhibitors for Alzheimer's disease: cerebrovascular disease as a predictor of patient outcomes
Chathu_2008_Brain.Cogn_68_59 Acetylcholine esterase activity and behavioral response in hypoxia induced neonatal rats: effect of glucose, oxygen and epinephrine supplementation
Chaudhuri_2008_Infect.Immun_76_4530 Amylase-binding protein B of Streptococcus gordonii is an extracellular dipeptidyl-peptidase
Chen_2008_J.Food.Sci_73_H103 Effect of polysaccharide from Auricularia auricula on blood lipid metabolism and lipoprotein lipase activity of ICR mice fed a cholesterol-enriched diet
Chen_2008_Pharmacol.Biochem.Behav_90_441 Water-soluble derivative of propolis mitigates scopolamine-induced learning and memory impairment in mice
Chen_2008_Atherosclerosis_200_102 Functional significance of lipoprotein lipase HindIII polymorphism associated with the risk of coronary artery disease
Chen_2008_Int.J.Obes.(Lond)_32_1694 Red mold rice prevents the development of obesity, dyslipidemia and hyperinsulinemia induced by high-fat diet
Chen_2008_Nature_452_429 Variations in DNA elucidate molecular networks that cause disease
Chen_2008_Langmuir_24_8877 Immobilization of lipases on hydrophobilized zirconia nanoparticles: highly enantioselective and reusable biocatalysts
Cheng_2008_Am.J.Physiol.Gastrointest.Liver.Physiol_295_G591 Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation
Cheng_2008_J.Pharmacol.Exp.Ther_327_683 Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes
Cheng_2008_Biochim.Biophys.Acta_1781_618 Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase
Cheng_2008_Zhonghua.Yi.Xue.Za.Zhi_88_2417 [Effects of tumor necrosis factor-alpha induced insulin resistance on adipose triglyceride lipase in mice]
Chia_2008_J.Clin.Endocrinol.Metab_93_3703 Incretin-based therapies in type 2 diabetes mellitus
Chilukuri_2008_Toxicol.Appl.Pharmacol_231_423 A repeated injection of polyethyleneglycol-conjugated recombinant human butyrylcholinesterase elicits immune response in mice
Cho_2008_Exp.Mol.Med_40_523 Association of lipoprotein lipase (LPL) single nucleotide polymorphisms with type 2 diabetes mellitus
Chou_2008_Biomed.Chromatogr_22_502 Determination of lipoprotein lipase activity in post heparin plasma of streptozotocin-induced diabetic rats by high-performance liquid chromatography with fluorescence detection
Chuah_2008_J.Neurosci_28_11369 Cholinergic augmentation modulates visual task performance in sleep-deprived young adults
Coelho_2008_Pediatr.Surg.Int_24_1017 Studies of RET gene expression and acetylcholinesterase activity in a series of sporadic Hirschsprung's disease
Colin_2008_Biochem.Biophys.Res.Commun_370_394 Exploring the active site cavity of human pancreatic lipase
Costantino_2008_BMC.Neurosci_9 Suppl 3_S6 Intranasal administration of acetylcholinesterase inhibitors
Costas_2008_Appl.Biochem.Biotechnol_151_578 Effects of organic solvents on immobilized lipase in pectin microspheres
Covarrubias_2008_Neurochem.Res_33_1558 The neuronal Kv4 channel complex
Croxtall_2008_Drugs_68_2387 Vildagliptin: a review of its use in the management of type 2 diabetes mellitus
Cucurachi_2008_J.Neurol_255_1949 Short-latency afferent inhibition predicts verbal memory performance in patients with multiple sclerosis
Cutuli_2008_Psychopharmacology.(Berl)_197_661 Cognitive performance of healthy young rats following chronic donepezil administration
da Silva_2008_Physiol.Behav_95_88 Serotonin receptors contribute to the promnesic effects of P. olacoides (Marapuama)
da Silva_2008_Int.J.Dev.Neurosci_26_339 Maternal caffeine intake affects acetylcholinesterase in hippocampus of neonate rats
Dai_2008_Biochem.Biophys.Res.Commun_374_485 Poly-3-hydroxybutyrate synthase from the periplasm of Escherichia coli
Dai_2008_Diabetes.Obes.Metab_10_506 Non-linear increase in GLP-1 levels in response to DPP-IV inhibition in healthy adult subjects
Davies_2008_Mol.Endocrinol_22_2496 The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma
Davis_2008_J.Expo.Sci.Environ.Epidemiol_18_564 Assessing intermittent pesticide exposure from flea control collars containing the organophosphorus insecticide tetrachlorvinphos
Dawson_2008_J.Hazard.Mater_157_308 Degradation of nerve agents by an organophosphate-degrading agent (OpdA)
De Caro_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_1 Occurrence of pancreatic lipase-related protein-2 in various species and its relationship with herbivore diet
De La Garza_2008_Pharmacol.Biochem.Behav_89_200 The acetylcholinesterase inhibitor rivastigmine does not alter total choices for methamphetamine, but may reduce positive subjective effects, in a laboratory model of intravenous self-administration in human volunteers
de Lima Portella_2008_Life.Sci_83_878 Oximes as inhibitors of low density lipoprotein oxidation
de Zwart_2008_Reprod.Toxicol_26_220 The ontogeny of drug metabolizing enzymes and transporters in the rat
Decker_2008_Bioorg.Med.Chem_16_4252 Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties
Deduchovas_2008_Ann.Anat_190_525 Morphologic pattern of myenteric neural plexus in colonic diverticular disease. A whole-mount study employing histochemical staining for acetylcholinesterase
Deiuliis_2008_Lipids_43_215 Developmental, hormonal, and nutritional regulation of porcine adipose triglyceride lipase (ATGL)
Delgado_2008_J.Antimicrob.Chemother_62_1207 The fusidic acid stimulon of Staphylococcus aureus
Deng_2008_J.Chromatogr.A_1198-1199_67 Direct separation of monoacylglycerol isomers by enantioselective high-performance liquid chromatography
Devkota_2008_J.Nat.Prod_71_1481 Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana
Dichgans_2008_Lancet.Neurol_7_310 Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL
Dizge_2008_Colloids.Surf.B.Biointerfaces_66_34 Covalent attachment of microbial lipase onto microporous styrene-divinylbenzene copolymer by means of polyglutaraldehyde
Djogbenou_2008_Acta.Trop_107_272 Presence of insensitive acetylcholinesterase in wild populations of Culex pipiens quinquefasciatus from Benin
Domingues_2008_Chemosphere_71_1877 In situ assay with the midge Kiefferulus calligaster for contamination evaluation in aquatic agro-systems in central Thailand
Doody_2008_CNS.Spectr_13_34 Cholinesterase inhibitors and memantine: best practices
Doralp_2008_Neurobiol.Learn.Mem_90_382 Cholinergic modulation of hippocampal CA1 basal-dendritic long-term potentiation
Dorandeu_2008_Toxicology_248_151 An unexpected plasma cholinesterase activity rebound after challenge with a high dose of the nerve agent VX
Dorfmeister_2008_Arterioscler.Thromb.Vasc.Biol_28_1866 Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding
Du_2008_Biosens.Bioelectron_24_475 Development of acetylcholinesterase biosensor based on CdTe quantum dots\/gold nanoparticles modified chitosan microspheres interface
Du_2008_Analyst_133_1790 Immobilization of acetylcholinesterase based on the controllable adsorption of carbon nanotubes onto an alkanethiol monolayer for carbaryl sensing
Du_2008_Toxicol.Lett_181_104 Effects of 3-benzidino-6-phenylpyridazine, as an acetylcholinesterase inhibitor, on outward potassium current in acutely isolated rat hippocampal pyramidal neurons
Ducharme_2008_Endocrinology_149_942 Lipid droplets in lipogenesis and lipolysis
Duysen_2008_Basic.Clin.Pharmacol.Toxicol_103_514 Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice
Dyer_2008_Schizophr.Res_102_88 High-dose galantamine augmentation inferior to placebo on attention, inhibitory control and working memory performance in nonsmokers with schizophrenia
Ebrahimpour_2008_BMC.Biotechnol_8_96 A modeling study by response surface methodology and artificial neural network on culture parameters optimization for thermostable lipase production from a newly isolated thermophilic Geobacillus sp. strain ARM
Edashige_2008_J.Nutr.Sci.Vitaminol.(Tokyo)_54_409 Inhibitory effect of pectin from the segment membrane of citrus fruits on lipase activity
Eilfeld_2008_Bioorg.Med.Chem_16_8127 Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides
Ellrichmann_2008_J.Clin.Endocrinol.Metab_93_3995 Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations
Fain_2008_Mol.Cell.Endocrinol_295_101 Stimulation of human omental adipose tissue lipolysis by growth hormone plus dexamethasone
Falfushinska_2008_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_148_223 Different responses of biochemical markers in frogs (Rana ridibunda) from urban and rural wetlands to the effect of carbamate fungicide
Fallarero_2008_Pharmacol.Res_58_215 Inhibition of acetylcholinesterase by coumarins: the case of coumarin 106
Fang_2008_J.Med.Chem_51_7666 NO-donating tacrine hybrid compounds improve scopolamine-induced cognition impairment and show less hepatotoxicity
Fang_2008_J.Med.Chem_51_713 Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates
Fang_2008_Bioorg.Med.Chem.Lett_18_2905 Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates
Farghaly_2008_Food.Chem.Toxicol_46_3111 Toxicological evaluation and bioavailability of (14)C-fenitrothion bound residues on soybeans towards experimental animals
Fernandez_2008_Am.J.Physiol.Endocrinol.Metab_295_E820 Disturbed cholesterol homeostasis in hormone-sensitive lipase-null mice
Fernandez_2008_Biochim.Biophys.Acta_1781_367 Lipolysis of the semi-solid self-emulsifying excipient Gelucire 44\/14 by digestive lipases
Fernyhough_2008_Cells.Tissues.Organs_188_359 Progeny from dedifferentiated bovine adipocytes display protracted adipogenesis
Finsterer_2008_J.Neurol.Sci_272_20 Cognitive decline as a manifestation of mitochondrial disorders (mitochondrial dementia)
Firth-Clark_2008_J.Chem.Inf.Model_48_296 De novo ligand design to partially flexible active sites: application of the ReFlex algorithm to carboxypeptidase A, acetylcholinesterase, and the estrogen receptor
Fisher_2008_Ann.Pharmacother_42_278 Prolonged QT interval, syncope, and delirium with galantamine
Fleck_2008_Arzneimittelforschung_58_543 A new way of data interpretation for cognition tests in rats used to characterise six choline esterase inhibitors with heterocyclic nitrogen bridgehead structure. Application in Alzheimer therapy
Fleury_2008_Rev.Prat_58_2217 [Myasthenia gravis]
Focosi_2008_J.Leukoc.Biol_84_331 Conditioning response to granulocyte colony-stimulating factor via the dipeptidyl peptidase IV-adenosine deaminase complex
Forstl_2008_Internist.(Berl)_49_353 [Antidementia drugs--response or non-response?]
Forstl_2008_Nervenarzt_79_617 [Treatment and care strategies for Alzheimer's disease and related dementias]
Fuh_2008_Acta.Neurol.Taiwan_17_153 Dementia in Taiwan: past, present, and future
Georgiev_2008_Prilozi_29_213 Association of PvuII polymorphism in the lipoprotein lipase gene with the coronary artery disease in Macedonian population
Goscinski_2008_APMIS_116_823 Dipeptidyl peptidase IV expression in cancer and stromal cells of human esophageal squamous cell carcinomas, adenocarcinomas and squamous cell carcinoma cell lines
Guay_2008_Consult.Pharm_23_598 Rivastigmine transdermal patch: role in the management of Alzheimer's disease
Gurusubramanian_2008_J.Environ.Biol_29_813 Pesticide usage pattern in tea ecosystem, their retrospects and alternative measures
Gwaltney_2008_Curr.Top.Med.Chem_8_1545 Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase IV
Herrmann_2008_CMAJ_179_1279 Diagnosis and treatment of dementia: 6. Management of severe Alzheimer disease
Hogan_2008_CMAJ_179_1019 Diagnosis and treatment of dementia: 5. Nonpharmacologic and pharmacologic therapy for mild to moderate dementia
Hou_2008_Endocr.Pract_14_1020 A case of severe neuropathy associated with hypertriglyceridemia
Hsieh_2008_Emerg.Med.J_25_781 Acute cholinergic syndrome following ingestion of contaminated herbal extract
Husain_2008_Neuropsychiatr.Dis.Treat_4_765 Present and prospective clinical therapeutic regimens for Alzheimer's disease
Iyer_2008_Drugs.Aging_25_1021 Medication withdrawal trials in people aged 65 years and older: a systematic review
Jacobs_2008_J.Biopharm.Stat_18_1197 Combined models for data from in vitro-in vivo correlation experiments
Jean_2008_Neuron.Glia.Biol_4_35 Glutamate elicits release of BDNF from basal forebrain astrocytes in a process dependent on metabotropic receptors and the PLC pathway
Jimenez_2008_Rev.Neurol_47_536 [Cognitive impairment associated to leukoaraiosis: its pathophysiology, clinical manifestations and treatment]
Jinyong_2008_Wei.Sheng.Wu.Xue.Bao_48_1276 [Strategies for exploiting microbial lipase resource and improving lipase biocatalyst--a review]
Kaduszkiewicz_2008_Evid.Based.Ment.Health_11_113 Review: cholinesterase inhibitors and memantine consistently but marginally improve symptoms of dementia
Kaibori_2008_Hepatogastroenterology_55_2151 Risk factors for early death due to recurrence after resection of large hepatocellular carcinomas
Kalonia_2008_Methods.Find.Exp.Clin.Pharmacol_30_529 Possible mechanism involved in sleep deprivation-induced memory dysfunction
Kalow_2008_Can.J.Anaesth_55_860 The relation of plasma cholinesterases to response to clinical doses of succinylcholine
Khan_2008_Int.J.Clin.Exp.Med_1_274 Adverse effects of pesticides residues on biochemical markers in pakistani tobacco farmers
Khan_2008_J.Clin.Pharm.Ther_33_669 Post-operative pain relief following intrathecal injection of acetylcholine esterase inhibitor during lumbar disc surgery: a prospective double blind randomized study
Kim_2008_Arch.Pharm.Res_31_1225 A new stilbene glucoside gallate from the roots of Polygonum multiflorum
Kim_2008_Pharmacol.Rev_60_470 The role of incretins in glucose homeostasis and diabetes treatment
Kobayashi_2008_Planta.Med_74_1716 Constituents of Rhodiola rosea showing inhibitory effect on lipase activity in mouse plasma and alimentary canal
Krentz_2008_Drugs_68_2131 New drugs for type 2 diabetes mellitus: what is their place in therapy?
Krintel_2008_PLoS.One_3_e3756 Ser649 and Ser650 are the major determinants of protein kinase A-mediated activation of human hormone-sensitive lipase against lipid substrates
Kurota_2008_Seishin.Shinkeigaku.Zasshi_110_571 [Clinical and pathological findings in dementia with Lewy bodies]
Lacko_2008_Head.Neck_30_836 Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer
Laks_2008_Curr.Opin.Psychiatry_21_562 Reports in pharmacological treatments in geriatric psychiatry: is there anything new or just adding to old evidence?
Lassiter_2008_Environ.Health.Perspect_116_1456 Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood
Lee_2008_Transplant.Proc_40_1353 Genetic variations in soluble epoxide hydrolase and graft function in kidney transplantation
Li_2008_Front.Biosci_13_3480 Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension
Lienqueo_2008_Biotechnol.Lett_30_1353 Influence of tryptophan tags on the purification of cutinase, secreted by a recombinant Saccharomyces cerevisiae, using cationic expanded bed adsorption and hydrophobic interaction chromatography
Liu_2008_J.Neurosci.Res_86_2792 Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment
Liu_2008_Zhongguo.Xiu.Fu.Chong.Jian.Wai.Ke.Za.Zhi_22_1026 [3D visualization research on microstructure of human ulnar nerve]
Liu_2008_Wei.Sheng.Wu.Xue.Bao_48_1543 [Cell surface display of Yarrowia lipolytica lipase Lip2 in Saccharomyces cerevisiae with a-agglutinin as carrier protein]
Lone_2008_J.Coll.Physicians.Surg.Pak_18_655 Familial chylomicronemia in a nine months old infant
Ma_2008_Zhongguo.Xiu.Fu.Chong.Jian.Wai.Ke.Za.Zhi_22_1073 [Experimental study on peripheral nerve plasticity in rats]
Machida_2008_DNA.Res_15_173 Genomics of Aspergillus oryzae: learning from the history of Koji mold and exploration of its future
Magrioti_2008_Bioorg.Med.Chem.Lett_18_5424 A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity
Maharajh_2008_Appl.Microbiol.Biotechnol_79_235 Multi-copy expression and fed-batch production of Rhodotorula araucariae epoxide hydrolase in Yarrowia lipolytica
Massoud_2008_Can.J.Neurol.Sci_35_508 Drug utilization review of cholinesterase inhibitors in Quebec
Meilanov_2008_Biofizika_53_613 [Temperature dependence of the acetylcholinesterase activity in synaptic membranes of the rat brain]
Melzer_2008_J.Ind.Microbiol.Biotechnol_35_485 Production of epoxide hydrolases in batch fermentations of Botryosphaeria rhodina
Micaelo_2008_J.Phys.Chem.B_112_2566 Protein structure and dynamics in ionic liquids. Insights from molecular dynamics simulation studies
Minami_2008_J.Toxicol.Sci_33_405 Regulation of insulin-like growth factor binding protein-1 and lipoprotein lipase by the aryl hydrocarbon receptor
Miron_2008_Chemosphere_74_1 Biochemical effects of clomazone herbicide on piava (Leporinus obtusidens)
Mittelman_2008_Am.J.Geriatr.Psychiatry_16_893 A three-country randomized controlled trial of a psychosocial intervention for caregivers combined with pharmacological treatment for patients with Alzheimer disease: effects on caregiver depression
Miyamoto_2008_Rinsho.Byori_56_761 [Relationship between glycated albumin (GA) and glycated hemoglobin (A1c) in 255 patients with liver diseases using cross-sectional laboratory data]
Mojtahedin_2008_Pak.J.Biol.Sci_11_2573 Effects of mepyramine and famotidine on the physostigmine-induced antinociception in the formalin test in rats
Monti_2008_Nat.Genet_40_529 Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease
Morisseau_2008_Pest.Manag.Sci_64_594 Gerry Brooks and epoxide hydrolases: four decades to a pharmaceutical
Moustafa_2008_Jpn.J.Vet.Res_56_109 Downregulation of male-specific cytochrome P450 by profenofos
Muller_2008_Child.Adolesc.Psychiatry.Ment.Health_2_33 Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa
Munoz-Torrero_2008_Curr.Med.Chem_15_2433 Acetylcholinesterase inhibitors as disease-modifying therapies for Alzheimer's disease
Nakamura_2008_Seishin.Shinkeigaku.Zasshi_110_577 [Diagnosis of and therapy for Alzheimer-type dementia]
Nandi_2008_J.Oleo.Sci_57_599 Lipase catalyzed synthesis of neutral glycerides rich in micronutrients from rice bran oil fatty acid distillate
Narbutaite_2008_Lett.Appl.Microbiol_47_555 Influence of baking enzymes on antimicrobial activity of five bacteriocin-like inhibitory substances produced by lactic acid bacteria isolated from Lithuanian sourdoughs
Nieoullon_2008_Curr.Med.Res.Opin_24_3357 Importance of circadian rhythmicity in the cholinergic treatment of Alzheimer's disease: focus on galantamine*
Nitta_2008_Bioorg.Med.Chem.Lett_18_5435 (3R)-3-amino-4-(2,4,5-trifluorophenyl)-N-{4-[6-(2-methoxyethoxy)benzothiazol-2-yl ]tetrahydropyran-4-yl}butanamide as a potent dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Pak-Dek_2008_J.Food.Sci_73_C595 Inhibitory effect of morinda citrifolia L. On lipoprotein lipase activity
Palmqvist_2008_Am.J.Alzheimers.Dis.Other.Demen_23_439 The usefulness of cube copying for evaluating treatment of Alzheimer's disease
Pande_2008_Cancer.Epidemiol.Biomarkers.Prev_17_2393 Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome
Patrizi_2008_Proc.Natl.Acad.Sci.U.S.A_105_13151 Synapse formation and clustering of neuroligin-2 in the absence of GABAA receptors
Paudyal_2008_JNMA.J.Nepal.Med.Assoc_47_251 Organophosphorus poisoning
Pejin_2008_J.Nat.Prod_71_1850 Synthesis and biological activities of thio-avarol derivatives
Pennetier_2008_Emerg.Infect.Dis_14_1707 Mixture for controlling insecticide-resistant malaria vectors
Perneczky_2008_MMW.Fortschr.Med_150_42 [Diagnosis and therapy of Alzheimer's disease: what's important for the family doctor?]
Petroianu_2008_Mini.Rev.Med.Chem_8_1328 Pyridinium oxime reactivators of cholinesterase inhibited by diisopropyl-fluorophosphate (DFP): predictive value of in-vitro testing for in-vivo efficacy
Phoopichayanun_2008_Nat.Prod.Res_22_1297 Complete NMR assignment and absolute configuration of feronielloside, a new acetylcholinesterase inhibitor from Feroniella lucida
Phowichit_2008_Commun.Agric.Appl.Biol.Sci_73_611 Insecticidal activity of Jatropha gossypifolia L. (Euphorbiaceae) and Cleome viscosa L. (Capparidacae) on Spodoptera litura (Lepidoptera: Noctuidae). Toxicity and carboxylesterase and glutathione-S-transferase activities studies
Piccione_2008_J.Vet.Diagn.Invest_20_795 Daily rhythm of serum lipase and alpha-amylase activity in fed and fasted dogs
Pio_2008_J.Ind.Microbiol.Biotechnol_35_59 Cutinase production by Fusarium oxysporum in liquid medium using central composite design
Poewe_2008_Int.J.Clin.Pract_62_1581 Diagnosis and management of Parkinson's disease dementia
Pohanka_2008_Protein.Pept.Lett_15_795 Cholinesterase biosensor construction - a review
Pohanka_2008_Neuro.Endocrinol.Lett_29_755 New performance of biosensor technology for Alzheimer's disease drugs: in vitro comparison of tacrine and 7-methoxytacrine
Pushparajah_2008_Mutat.Res_640_153 Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: studies using precision-cut tissue slices
Qi_2008_Zhongguo.Xiu.Fu.Chong.Jian.Wai.Ke.Za.Zhi_22_1031 [Preliminary research of 3D reconstruction of short-segment common peroneal nerve functional fascicles]
Qiu_2008_Postgrad.Med.J_84_498 Association study between adolescent idiopathic scoliosis and the DPP9 gene which is located in the candidate region identified by linkage analysis
Rachokarn_2008_Commun.Agric.Appl.Biol.Sci_73_451 Impact of botanical extracts derived from leaf extracts Melia azedarach L. (Meliaceae) and Amaranthus viridis L. (Amaranthaceae) on populations of Spodoptera exigua (Hubner) (Lepidoptera: Noctuidae) and detoxification enzyme activities
Randolt_2008_Arch.Insect.Biochem.Physiol_69_155 Immune-related proteins induced in the hemolymph after aseptic and septic injury differ in honey bee worker larvae and adults
Reissner_2008_Proc.Natl.Acad.Sci.U.S.A_105_15124 Mutational analysis of the neurexin\/neuroligin complex reveals essential and regulatory components
Ricart-Jane_2008_Cell.Physiol.Biochem_22_525 Nitric oxide and the release of lipoprotein lipase from white adipose tissue
Richard_2008_Neurology_71_1967 The CHRNE 1293insG founder mutation is a frequent cause of congenital myasthenia in North Africa
Richter_2008_Vasc.Health.Risk.Manag_4_753 Emerging role of dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes
Ridl_2008_Malar.J_7_194 A pre-intervention study of malaria vector abundance in Rio Muni, Equatorial Guinea: their role in malaria transmission and the incidence of insecticide resistance alleles
Rispoli_2008_Biotechnol.Prog_24_648 Optimization of the media ingredients for cutinase production from Colleotrichum lindemuthianum using mixture design experiments
Roxas_2008_Altern.Med.Rev_13_307 The role of enzyme supplementation in digestive disorders
Rozengart_2008_Dokl.Biochem.Biophys_421_218 Specificity of cholinesterase hydrolysis of piperidylcholine and its derivatives
Rubio_2008_Curr.Genet_54_301 Cloning and characterization of the Thcut1 gene encoding a cutinase of Trichoderma harzianum T34
Ryuda_2008_Zoolog.Sci_25_746 Analysis of hunger-driven gene expression in the Drosophila melanogaster larval central nervous system
Salmon_2008_Rev.Med.Liege_63_570 [A transdermal patch of rivastigmine (Exelon)]
Sangnoi_2008_Mar.Drugs_6_578 Acetylcholinesterase-inhibiting activity of pyrrole derivatives from a novel marine gliding bacterium, Rapidithrix thailandica
Sano_2008_CNS.Drugs_22_887 Preventing Alzheimer's disease : separating fact from fiction
Shaked_2008_Ann.N.Y.Acad.Sci_1148_269 Stress-induced alternative splicing modulations in brain and periphery: acetylcholinesterase as a case study
Shariat_2008_Can.J.Urol_15_4363 Screening for prostate cancer: an update
Shaygannejad_2008_Can.J.Neurol.Sci_35_476 Effects of rivastigmine on memory and cognition in multiple sclerosis
Shi_2008_Phytother.Res_22_1264 Inhibition of soluble epoxide hydrolase by extracts derived from inflammation-treating Chinese medicinal herbs
Shichijo_2008_J.Am.Chem.Soc_130_12230 Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis
Shipovskov_2008_Biotechnol.Prog_24_1262 Homogeneous esterification by lipase from Burkholderia cepacia in the fluorinated solvent
Silver_2008_Neuron_60_904 Cholinergic enhancement reduces spatial spread of visual responses in human early visual cortex
Singh_2008_J.Biochem.Mol.Toxicol_22_363 Atrazine-induced alterations in rat erythrocyte membranes: ameliorating effect of vitamin E
Singh_2008_Beilstein.J.Org.Chem_4_20 Synthesis of (S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile: a key intermediate for dipeptidyl peptidase IV inhibitors
Slotkin_2008_Environ.Health.Perspect_116_1308 Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood
Soltani_2008_Commun.Agric.Appl.Biol.Sci_73_659 Evaluation of halofenozide against prey mosquito larvae Culex pipiens and the predator fish Gambusia affinis: impact on growth and enzymatic activities
Soukup_2008_Neuro.Endocrinol.Lett_29_759 The effect of HI-6 on cholinesterases and on the cholinergic system of the rat bladder
Souza_2008_Rev.Inst.Med.Trop.Sao.Paulo_50_269 Secretion of five extracellular enzymes by strains of chromoblastomycosis agents
Srinivasan_2008_Postgrad.Med.J_84_524 Recent advances in the management of type 2 diabetes mellitus: a review
Sudhof_2008_Nature_455_903 Neuroligins and neurexins link synaptic function to cognitive disease
Suh_2008_Curr.Opin.Psychiatry_21_546 Mental health economics, health service provision, and the practice of geriatric psychiatry
Sui_2008_Insect.Mol.Biol_17_523 Effects of classical insect hormones on the expression profiles of a lipase gene from the cotton bollworm (Helicoverpa armigera)
Sumi_2008_J.Toxicol.Sci_33_485 Chinese dumpling scare hits Japan--a case of methamidophos food poisoning
Sura_2008_J.Histochem.Cytochem_56_551 Distribution and expression of soluble epoxide hydrolase in human brain
Svedendahl_2008_Chembiochem_9_2443 Direct epoxidation in Candida antarctica lipase B studied by experiment and theory
Tadros_2008_J.Egypt.Soc.Parasitol_38_585 Molluscicidal and schistosomicidal activities of a steroidal saponin containing fraction from Dracaena fragrans (L.)
Torres_2008_J.Biosci.Bioeng_106_559 Stepwise esterification of phytosterols with conjugated linoleic acid catalyzed by Candida rugosa lipase in solvent-free medium
Ulu_2008_J.Cardiovasc.Pharmacol_52_314 Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model
Vaidya_2008_Curr.Drug.Targets_9_911 Glucagon like peptides-1 modulators as newer target for diabetes
Volzke_2008_Pancreas_37_411 Prevalence and determinants of increased serum lipase levels in a general population
Walz_2008_J.AOAC.Int_91_1130 Reflectometric cutinase assay for rapid screening of contaminants and residues of insecticidal organophosphates and carbamates
Wani_2008_Cardiol.Clin_26_639 Dipeptidyl peptidase-4 as a new target of action for type 2 diabetes mellitus: a systematic review
Watson_2008_Fungal.Genet.Biol_45_1348 A model for integration of DNA into the genome during transformation of Fusarium graminearum
Winblad_2008_Expert.Opin.Drug.Deliv_5_1377 Use of rivastigmine transdermal patch in the treatment of Alzheimer's disease
Woods_2008_BMC.Biotechnol_8_95 Hairy-root organ cultures for the production of human acetylcholinesterase
Xie_2008_FEMS.Microbiol.Lett_289_181 Esterase SeE of Streptococcus equi ssp. equi is a novel nonspecific carboxylic ester hydrolase
Yin_2008_Clin.Invest.Med_31_E248 Effect of tanshinone on the levels of nitric oxide synthase and acetylcholinesterase in the brain of Alzheimer's disease rat model
Zhang_2008_Protein.Pept.Lett_15_1132 Predicting lipase types by improved Chou's pseudo-amino acid composition
Zhang_2008_World.J.Pediatr_4_295 Diagnosis and surgical treatment of isolated hypoganglionosis
Zhang_2008_Pharmacogenet.Genomics_18_45 Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population
Zhang_2008_Zhonghua.Zhong.Liu.Za.Zhi_30_848 [Correlation of DPPIV expression with clinicopathological features and prognosis in epithelial ovarian carcinoma]
Zhang_2008_Stroke_39_2073 Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia
Zheng_2008_Zhongguo.Zhong.Yao.Za.Zhi_33_2385 [Effects of total glucosides of paeony on enhancing insulin sensitivity and antagonizing nonalcoholic fatty liver in rats]
Zullo_2008_Food.Microbiol_25_970 Lipolytic yeasts distribution in commercial extra virgin olive oil
Ahmed_2008_J.Enzyme.Inhib.Med.Chem_23_912 Comparative study of the inhibitory effect of antidepressants on cholinesterase activity in Bungarus sindanus (krait) venom, human serum and rat striatum
Anguiano_2008_Environ.Toxicol.Chem_27_2117 Enhanced esterase activity and resistance to azinphosmethyl in target and nontarget organisms
Araujo_2008_Bull.Entomol.Res_98_417 Enhanced activity of carbohydrate- and lipid-metabolizing enzymes in insecticide-resistant populations of the maize weevil, Sitophilus zeamais
Behl_2008_Int.Psychogeriatr_20_1141 The effect of cholinesterase inhibitors on decline in multiple functional domains in Alzheimer's disease: a two-year observational study in the Sunnybrook dementia cohort
Boone_2008_Environ.Toxicol.Chem_27_1561 Examining the single and interactive effects of three insecticides on amphibian metamorphosis
Caldas_2008_Clin.Toxicol.(Phila)_46_1058 Poisonings with pesticides in the Federal District of Brazil
De La Garza_2008_Int.J.Neuropsychopharmacol_11_729 Evaluation of the cardiovascular and subjective effects of rivastigmine in combination with methamphetamine in methamphetamine-dependent human volunteers
Eaton_2008_Crit.Rev.Toxicol_38 Suppl 2_1 Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment
Frasco_2008_Sci.Total.Environ_404_88 Does mercury interact with the inhibitory effect of dichlorvos on Palaemon serratus (Crustacea: Decapoda) cholinesterase?
Frenzilli_2008_Aquat.Toxicol_89_188 Cellular responses in the cyprinid Leuciscus cephalus from a contaminated freshwater ecosystem
Fujiki_2008_J.Clin.Neurosci_15_791 Neuroprotective and antiamnesic effect of donepezil, a nicotinic acetylcholine-receptor activator, on rats with concussive mild traumatic brain injury
Fukushima_2008_Bioorg.Med.Chem_16_4093 Synthesis and structure-activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
Furlani_2008_Auton.Neurosci_144_30 Morphological and quantitative study of ganglionated plexus of Calomys callosus trachea
Gabrovska_2008_Int.J.Biol.Macromol_43_339 The influence of the support nature on the kinetics parameters, inhibition constants and reactivation of immobilized acetylcholinesterase
Gamsjager_2008_Clin.Chem.Lab.Med_46_1140 Half-lives of albumin and cholinesterase in critically ill patients
Garber_2008_Diabetes.Obes.Metab_10_1047 Effects of vildagliptin on glucose control in patients with type 2 diabetes inadequately controlled with a sulphonylurea
Garcia_2008_Clin.Biochem_41_474 Butyrylcholinesterase activity is reduced in haemodialysis patients: is there association with hyperhomocysteinemia and\/or oxidative stress?
Garcia-Ayllon_2008_Brain_131_2946 Brain cholinergic impairment in liver failure
Gaur_2008_Appl.Biochem.Biotechnol_151_160 Protein-coated microcrystals of Pseudomonas aeruginosa PseA lipase
Ge_2008_J.Phys.Chem.B_112_14319 Molecular fundamentals of enzyme nanogels
Gin_2008_J.Biol.Chem_283_29554 The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons
Giuliano_2008_Neurochem.Int_52_1343 Increases in cholinergic neurotransmission measured by using choline-sensitive microelectrodes: enhanced detection by hydrolysis of acetylcholine on recording sites?
Golomb_2008_Proc.Natl.Acad.Sci.U.S.A_105_E94 Correction for Golomb, Reply to Blazer et al.: Flawed challenges to 'Acetylcholinesterase inhibitors and Gulf War illnesses',
Goncalves_2008_Mol.Cell.Neurosci_38_526 A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner
Gongadze_2008_Georgian.Med.News__44 The mechanisms of neurodegenerative processes and current pharmacotherapy of Alzheimer's disease
Goto_2008_Eur.J.Pharmacol_583_84 Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe\/PS1dE9 mouse model of Alzheimer's disease
Grarup_2008_J.Clin.Endocrinol.Metab_93_2294 The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects
Griffith_2008_Epilepsy.Behav_13_376 The safety and tolerability of galantamine in patients with epilepsy and memory difficulties
Gu_2008_Clin.Exp.Pharmacol.Physiol_35_1433 Glucose regulation of dipeptidyl peptidase IV gene expression is mediated by hepatocyte nuclear factor-1alpha in epithelial intestinal cells
Guerra_2008_Mol.Cell.Neurosci_38_1 Identification of cis-acting elements involved in acetylcholinesterase RNA alternative splicing
Guieysse_2008_Chembiochem_9_1308 A structure-controlled investigation of lipase enantioselectivity by a path-planning approach
Hackenberger_2008_Ecotoxicol.Environ.Saf_71_583 Effect of temephos on cholinesterase activity in the earthworm Eisenia fetida (Oligochaeta, Lumbricidae)
Hama_2008_Appl.Microbiol.Biotechnol_81_637 Preparation and comparative characterization of immobilized Aspergillus oryzae expressing Fusarium heterosporum lipase for enzymatic biodiesel production
Han_2008_Am.J.Physiol.Heart.Circ.Physiol_295_H382 Maternal undernutrition induces differential cardiac gene expression in pulmonary hypertensive steers at high elevation
Harati_2008_Neurosci_153_72 Selective cholinergic lesions in the rat nucleus basalis magnocellularis with limited damage in the medial septum specifically alter attention performance in the five-choice serial reaction time task
Harmon_2008_Methods_46_18 Role of non-linear optics and multiple photon absorbance in enhancing sensitivity of enzyme-based chemical agent detectors
Harris_2008_Cell.Signal_20_2296 The interferon-gamma-mediated inhibition of lipoprotein lipase gene transcription in macrophages involves casein kinase 2- and phosphoinositide-3-kinase-mediated regulation of transcription factors Sp1 and Sp3
Hartl_2008_Langmuir_24_9898 Enzyme-modified field effect transistors based on surface-conductive single-crystalline diamond
Hayashida_2008_Eur.J.Pharmacol_598_21 Multiplicative interactions to enhance gabapentin to treat neuropathic pain
Henson-Ramsey_2008_Arch.Environ.Contam.Toxicol_55_481 Acute toxicity and tissue distributions of malathion in Ambystoma tigrinum
Henson-Ramsey_2008_Bull.Environ.Contam.Toxicol_80_220 Assessment of the effect of varying soil organic matter content on the bioavailability of malathion to the common nightcrawler, Lumbricus terrestris L
Herholz_2008_Eur.J.Nucl.Med.Mol.Imaging_35 Suppl 1_S25 Acetylcholine esterase activity in mild cognitive impairment and Alzheimer's disease
Hirano_2008_Mov.Disord_23_1154 PET study of brain acetylcholinesterase in cerebellar degenerative disorders
Hirasawa_2008_Bioorg.Med.Chem_16_6167 Lycoparins A-C, new alkaloids from Lycopodium casuarinoides inhibiting acetylcholinesterase
Hoffmann_2008_Clin.Toxicol.(Phila)_46_694 Acute poisoning by pirimicarb: clinical and toxicological features
Horne_2008_Gene_411_27 Multiple tandem gene duplications in a neutral lipase gene cluster in Drosophila
Hornick_2008_Biochem.Pharmacol_76_236 Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: brain ACh increasing and memory improving properties
Hsu_2008_J.Agric.Food.Chem_56_1992 Promoter analysis and differential expression of the Candida rugosa lipase gene family in response to culture conditions
Hu_2008_J.Am.Soc.Mass.Spectrom_19_865 Enzyme inhibitor screening by electrospray mass spectrometry with immobilized enzyme on magnetic silica microspheres
Hu_2008_J.Agric.Food.Chem_56_10988 Optimization of lipase-catalyzed synthesis of ginsenoside Rb1 esters using response surface methodology
Huang_2008_Bioresour.Technol_99_5459 Covalent immobilization of lipase from Candida rugosa onto poly(acrylonitrile-co-2-hydroxyethyl methacrylate) electrospun fibrous membranes for potential bioreactor application
Hubbard_2008_Eur.J.Clin.Pharmacol_64_895 Plasma esterases and inflammation in ageing and frailty
Hung_2008_J.Ethnopharmacol_119_74 Cholinesterase inhibitory and anti-amnesic activity of alkaloids from Corydalis turtschaninovii
Ibrahim_2008_J.Pharm.Biomed.Anal_48_1345 Association mechanism of four acetylcholinesterase inhibitors (AChEIs) with human serum albumin: a biochromatographic approach
Imamura_2008_Neurocase_14_271 The effect of donepezil on increased regional cerebral blood flow in the posterior cingulate cortex of a patient with Parkinson's disease dementia
Imamura_2008_J.Lipid.Res_49_1431 A novel method for measuring human lipoprotein lipase and hepatic lipase activities in postheparin plasma
Ishima_2008_Prog.Neuropsychopharmacol.Biol.Psychiatry_32_1656 Potentiation of nerve growth factor-induced neurite outgrowth in PC12 cells by donepezil: role of sigma-1 receptors and IP3 receptors
Jang_2008_Phytother.Res_22_544 Inhibition of cholinesterase and amyloid-beta aggregation by resveratrol oligomers from Vitis amurensis
Jarvie_2008_Pharmacol.Res_58_297 Potentiation by cholinesterase inhibitors of cholinergic activity in rat isolated stomach and colon
Jayasundara_2008_Bull.Environ.Contam.Toxicol_80_374 Effect of repeated application of fenthion as a mosquito larvicide on Nile tilapia (Oreochromis niloticus) inhabiting selected water canals in Sri Lanka
Jensen_2008_J.Lipid.Res_49_870 Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype?
Jeong_2008_Eur.J.Pharmacol_588_78 Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice
Jeromin_2008_Biotechnol.Lett_30_925 A new irreversible enzyme-aided esterification method in organic solvents
Jia_2008_J.Pharmacol.Sci_107_167 Blocking histamine H(1) improves learning and mnemonic dysfunction in mice with social isolation plus repeated methamphetamine injection
Jiang_2008_Biomacromolecules_9_3246 Lipase-catalyzed synthesis of aliphatic polyesters via copolymerization of lactone, dialkyl diester, and diol
Jing_2008_Chirality_20_724 Determination of absolute configuration of secondary alcohols using lipase-catalyzed kinetic resolutions
Jocken_2008_Physiol.Behav_94_219 Catecholamine-induced lipolysis in adipose tissue and skeletal muscle in obesity
Jocken_2008_Histochem.Cell.Biol_129_535 Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific
Joerchel_2008_Int.J.Dev.Neurosci_26_301 Oligomeric beta-amyloid(1-42) induces the expression of Alzheimer disease-relevant proteins in cholinergic SN56.B5.G4 cells as revealed by proteomic analysis
John_2008_Anal.Bioanal.Chem_391_97 LC-MS-based procedures for monitoring of toxic organophosphorus compounds and verification of pesticide and nerve agent poisoning
Johnson_2008_Biochem.J_411_507 Interaction of acetylcholinesterase with the G4 domain of the laminin alpha1-chain
Johnson_2008_FEBS.J_275_5129 Non-enzymatic developmental functions of acetylcholinesterase--the question of redundancy
Jortner_2008_Toxicol.Appl.Pharmacol_233_162 Effect of stress at dosing on organophosphate and heavy metal toxicity
Joseph_2008_Biotechnol.Adv_26_457 Cold active microbial lipases: some hot issues and recent developments
Joshi_2008_Phytother.Res_22_1581 Pharmacological and biological screening of ascorbigen: protection against glucose-induced endothelial cell toxicity
Jung_2008_Mar.Pollut.Bull_57_599 Biomarker responses in caged rockfish (Sebastes schlegeli) from Masan Bay and Haegeumgang, South Korea
Kaizer_2008_Neurochem.Res_33_2294 Effect of long-term exposure to aluminum on the acetylcholinesterase activity in the central nervous system and erythrocytes
Kajita_2008_Diabetes.Res.Clin.Pract_81_144 Effect of fasting on PPARgamma and AMPK activity in adipocytes
Kamboj_2008_Cell.Mol.Neurobiol_28_961 Mitochondrial oxidative stress and dysfunction in rat brain induced by carbofuran exposure
Kao_2008_Anal.Chem_80_4065 Reagentless pH-stat for microliter fluid specimens
Kar_2008_J.Ind.Microbiol.Biotechnol_35_1053 Investigation of the effect of different extracellular factors on the lipase production by Yarrowia lipolityca on the basis of a scale-down approach
Karasova_2008_Int.J.Mol.Sci_9_2243 Effect of several new and currently available oxime cholinesterase reactivators on tabun-intoxicated rats
Karra-Chaabouni_2008_Colloids.Surf.B.Biointerfaces_66_168 Physical immobilization of Rhizopus oryzae lipase onto cellulose substrate: activity and stability studies
Kasai_2008_J.Pharmacol.Sci_108_40 Antidiabetic and hypolipidemic effects of a novel dual peroxisome proliferator-activated receptor (PPAR) alpha\/gamma agonist, E3030, in db\/db mice and beagle dogs
Kassa_2008_J.Enzyme.Inhib.Med.Chem_23_776 A comparison of the therapeutic and reactivating efficacy of newly developed bispyridinium compounds (K206, K269) with currently available oximes against tabun in rats and mice
Kawakami_2008_Ecotoxicology_17_221 Monitoring of cholinesterase-inhibiting activity in water from the Tone canal, Japan, as a biomarker of ecotoxicity
Kelly_2008_Schizophr.Res_103_161 Lack of beneficial galantamine effect for smoking behavior: a double-blind randomized trial in people with schizophrenia
Keng_2008_Bioresour.Technol_99_6097 Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor
Kent_2008_J.Med.Genet_45_519 X-linked ichthyosis (steroid sulfatase deficiency) is associated with increased risk of attention deficit hyperactivity disorder, autism and social communication deficits
Kerfelec_2008_Proteins_73_828 Computational study of colipase interaction with lipid droplets and bile salt micelles
Keseru_2008_FASEB.J_22_4306 Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response
Kewalramani_2008_Am.J.Physiol.Endocrinol.Metab_295_E137 Acute dexamethasone-induced increase in cardiac lipoprotein lipase requires activation of both Akt and stress kinases
Key_2008_Sci.Total.Environ_399_28 Toxicity and physiological effects of brominated flame retardant PBDE-47 on two life stages of grass shrimp, Palaemonetes pugio
Key_2008_Environ.Toxicol_23_153 Effects of the statin antihyperlipidemic agent simvastatin on grass shrimp, Palaemonetes pugio
Kim_2008_J.Med.Chem_51_589 Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines
Kim_2008_Org.Lett_10_1295 Highly enantioselective dynamic kinetic resolution of 1,2-diarylethanols by a lipase-ruthenium couple
Kim_2008_Mol.Endocrinol_22_477 Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiter
Kiran_2008_Bioprocess.Biosyst.Eng_31_483 Optimization of extracellular psychrophilic alkaline lipase produced by marine Pseudomonas sp. (MSI057)
Kobayashi_2008_J.Clin.Endocrinol.Metab_93_2877 The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets
Koga_2008_Diabetes.Res.Clin.Pract_81_258 CLD (chronic liver diseases)-HbA1C as a suitable indicator for estimation of mean plasma glucose in patients with chronic liver diseases
Koitka_2008_Anal.Biochem_381_113 Determination of rat serum esterase activities by an HPLC method using S-acetylthiocholine iodide and p-nitrophenyl acetate
Koivisto_2008_Diabetologia_51_1088 Discovery of dipeptidyl-peptidase IV--a 40 year journey from bench to patient
Kondo_2008_Macromol.Biosci_8_533 Lipase-catalyzed ring-opening polymerization of molecularly pure cyclic oligomers for use in synthesis and chemical recycling of aliphatic polyesters
Koyano_2008_Hepatol.Res_38_696 Common null variant, Arg192Stop, in a G-protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity
Kram_2008_Plant.Mol.Biol_68_173 Identification, cloning and characterization of a GDSL lipase secreted into the nectar of Jacaranda mimosifolia
Kredel_2008_Anaesthesist_57_1172 [Cholestasis and liver dysfunction in critical care patients]
Kristoff_2008_Chemosphere_72_1333 Effects of azinphos-methyl exposure on enzymatic and non-enzymatic antioxidant defenses in Biomphalaria glabrata and Lumbriculus variegatus
Krzeslak_2008_Appl.Environ.Microbiol_74_1402 Lipase expression in Pseudomonas alcaligenes is under the control of a two-component regulatory system
Kumar_2008_Phytother.Res_22_1563 Protective effect of quercetin against ICV colchicine-induced cognitive dysfunctions and oxidative damage in rats
Kusumawati_2008_J.Proteome.Res_7_4508 Characterization of the secretome of suspension cultures of Medicago species reveals proteins important for defense and development
Lai_2008_Brain.Res.Bull_77_420 Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder
Lam_2008_Neurosci.Lett_438_90 Effect of cholinergic denervation on hepatic fibrosis induced by carbon tetrachloride in rats
Lampidonis_2008_Gene_427_65 Cloning and functional characterization of the 5' regulatory region of ovine Hormone Sensitive Lipase (HSL) gene
Lannfelt_2008_Lancet.Neurol_7_779 Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial
Lassalle_2008_Bioprocess.Biosyst.Eng_31_499 Lipase-catalyzed copolymerization of lactic and glycolic acid with potential as drug delivery devices
Lau_2008_Mol.Pharmacol_74_1392 Muscarinic modulation of synaptic transmission via endocannabinoid signalling in the rat midbrain periaqueductal gray
Lau_2008_Mol.Cell.Neurosci_39_429 Myocyte enhancer factor 2 mediates acetylcholine-induced expression of acetylcholinesterase-associated collagen ColQ in cultured myotubes
Lee_2008_J.Clin.Epidemiol_61_1152 Published randomized controlled trials of drug therapy for dementia often lack complete data on harm
Lee_2008_J.Nucl.Med_49_2006 Changes in cerebral glucose metabolism in patients with Parkinson disease with dementia after cholinesterase inhibitor therapy
Lekhal_2008_Nutr.Metab.Cardiovasc.Dis_18_700 Decreased lipoprotein lipase activity and increased postprandial concentrations of triglyceride-rich lipoproteins in offspring of elderly survivors of myocardial infarction
Lekhal_2008_Lipids_43_507 Increased postprandial triglyceride-rich lipoprotein levels in elderly survivors of myocardial infarction
Leon_2008_Bioorg.Med.Chem_16_7759 New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties
Leonetti_2008_Bioorg.Med.Chem_16_7450 Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors
Li_2008_Ann.Epidemiol_18_760 Association of the lipoprotein lipase gene T+495G polymorphism with central obesity and serum lipids in a twin study
Li_2008_Neuropsychopharmacology_33_2820 Nicotinic acetylcholine receptors and modulation of learning in 4- and 27-month-old rabbits
Li_2008_Lipids_43_301 Molecular mechanism of age-specific hepatic lipid accumulation in PPARalpha (+\/-):LDLR (+\/-) mice, an obese mouse model
Liapi_2008_Metab.Brain.Dis_23_289 Equilibrated diet restores the effects of early age choline-deficient feeding on rat brain antioxidant status and enzyme activities: the role of homocysteine, L-phenylalanine and L-alanine
Limpeanchob_2008_J.Ethnopharmacol_120_112 Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture
Lin_2008_Clin.Chim.Acta_388_15 Thyroglobulin and human thyroid cancer
Linde-Arias_2008_Sci.Total.Environ_399_186 Biomarkers in an invasive fish species, Oreochromis niloticus, to assess the effects of pollution in a highly degraded Brazilian River
Linde-Arias_2008_Environ.Pollut_156_974 Multibiomarker approach in fish to assess the impact of pollution in a large Brazilian river, Paraiba do Sul
Liperoti_2008_Curr.Neuropharmacol_6_117 Antipsychotics for the treatment of behavioral and psychological symptoms of dementia (BPSD)
Liu_2008_Chemistry_14_9951 Nanoparticle-based electrochemical immunosensor for the detection of phosphorylated acetylcholinesterase: an exposure biomarker of organophosphate pesticides and nerve agents
Liu_2008_Gene_420_57 A rice serine carboxypeptidase-like gene OsBISCPL1 is involved in regulation of defense responses against biotic and oxidative stress
Liu_2008_Neurosci.Lett_434_195 Release of acetylcholine by syringin, an active principle of Eleutherococcus senticosus, to raise insulin secretion in Wistar rats
Liu_2008_Phytomedicine_15_1140 Saponins (Ginsenosides) from stems and leaves of Panax quinquefolium prevented high-fat diet-induced obesity in mice
Liu_2008_Am.J.Physiol.Regul.Integr.Comp.Physiol_295_R1794 Enteral nutrients potentiate the intestinotrophic action of glucagon-like peptide-2 in association with increased insulin-like growth factor-I responses in rats
Liu_2008_Antonie.Van.Leeuwenhoek_94_245 Cloning, characterization and expression of the extracellular lipase gene from Aureobasidium pullulans HN2-3 isolated from sea saltern
Locke_2008_J.Vis.Exp__ Paradigms for pharmacological characterization of C. elegans synaptic transmission mutants
Loria_2008_Eur.J.Neurosci_28_633 Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide
Lorke_2008_Neurotoxicol_29_663 Effect of intrathecal pralidoxime administration upon survival of rats exposed to the organophosphate paraoxon
Lu_2008_Bioresour.Technol_99_6070 Immobilized lipase Candida sp. 99-125 catalyzed methanolysis of glycerol trioleate: solvent effect
Lumor_2008_J.Agric.Food.Chem_56_10396 Esterification and hydrolytic activities of Candida rugosa lipase isoform 1 (LIP1) immobilized on celite 545, duolite A7, and sephadex G-25
Ma_2008_Phytochemistry_69_2022 In vitro production of huperzine A, a promising drug candidate for Alzheimer's disease
Machreki-Ajmi_2008_Ecotoxicology_17_802 Assessment of sediment\/water contamination by in vivo transplantation of the cockles Cerastoderma glaucum from a non contaminated to a contaminated area by cadmium
Maharajh_2008_Lett.Appl.Microbiol_47_520 Effect of an exponential feeding regime on the production of Rhodotorula araucariae epoxide hydrolase in Yarrowia lipolytica
Maia_2008_Planta.Med_74_1457 Acylphenols from Myristica crassa as new acetylcholinesterase inhibitors
Maione_2008_Br.J.Pharmacol_155_775 Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms
Maire_2008_Am.J.Gastroenterol_103_2871 Intraductal papillary mucinous neoplasms of the pancreas: performance of pancreatic fluid analysis for positive diagnosis and the prediction of malignancy
Maity_2008_J.Org.Chem_73_5629 Efficient and selective enzymatic acylation reaction: separation of furanosyl and pyranosyl nucleosides
Malouf_2008_Cochrane.Database.Syst.Rev__CD004514 Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people
Marcos_2008_Br.J.Pharmacol_155_434 Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat
Marighetto_2008_Psychopharmacology.(Berl)_197_499 Comparative effects of the alpha7 nicotinic partial agonist, S 24795, and the cholinesterase inhibitor, donepezil, against aging-related deficits in declarative and working memory in mice
Martinez-Lopez_2008_Clin.Sci.(Lond)_115_245 Cancer-associated differences in acetylcholinesterase activity in bronchial aspirates from patients with lung cancer
Masson_2008_FEBS.J_275_2617 Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters
Mateos_2008_J.Agric.Food.Chem_56_10960 New lipophilic tyrosyl esters. Comparative antioxidant evaluation with hydroxytyrosyl esters
Matsuyama-Yokono_2008_Biochem.Pharmacol_76_98 ASP8497 is a novel selective and competitive dipeptidyl peptidase-IV inhibitor with antihyperglycemic activity
Maxwell_2008_Toxicol.Appl.Pharmacol_231_157 A structure-activity analysis of the variation in oxime efficacy against nerve agents
Mazor_2008_Mol.Pharmacol_74_755 Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase
McCarney_2008_Int.J.Geriatr.Psychiatry_23_1222 Ginkgo biloba for mild to moderate dementia in a community setting: a pragmatic, randomised, parallel-group, double-blind, placebo-controlled trial
McEwen_2008_Mol.Biol.Cell_19_3836 UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin
McNamara_2008_J.Emerg.Med_35_167 Acute colonic pseudo-obstruction: rapid correction with neostigmine in the emergency department
Mello_2008_Biochem.Biophys.Res.Commun_374_460 Expression of carboxylesterase and lipase genes in rat liver cell-types
Michel_2008_Naunyn.Schmiedebergs.Arch.Pharmacol_377_205 Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism?
Militante_2008_Mol.Pharmacol_74_764 Activation and block of the adult muscle-type nicotinic receptor by physostigmine: single-channel studies
Mingrone_2008_Obesity.(Silver.Spring)_16_1831 Prolactin and insulin ultradian secretion and adipose tissue lipoprotein lipase expression in severely obese women after bariatric surgery
Mirajkar_2008_Biochem.Pharmacol_76_1047 In vitro sensitivity of cholinesterases and [3H]oxotremorine-M binding in heart and brain of adult and aging rats to organophosphorus anticholinesterases
Mitchell_2008_Biochim.Biophys.Acta_1784_705 An analytical method for determining relative specificities for sequential reactions catalyzed by the same enzyme: general formulation
Miyazawa_2008_Biotechnol.Lett_30_1783 Resolution of secondary alcohols via Carica papaya lipase-catalyzed enantioselective acylation
Miyoshi_2008_J.Cell.Biochem_105_1430 Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes
Montedonico_2008_Pediatr.Surg.Int_24_785 Histochemical staining of rectal suction biopsies as the first investigation in patients with chronic constipation
Montenegro_2008_Biol.Chem_389_425 Human butyrylcholinesterase components differ in aryl acylamidase activity
Mor_2008_J.Cell.Mol.Med_12_479 Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility
Moreau_2008_Hippocampus_18_610 Neuroanatomical and behavioral effects of a novel version of the cholinergic immunotoxin mu p75-saporin in mice
Mormeneo_2008_Appl.Microbiol.Biotechnol_80_437 Efficient secretion of Bacillus subtilis lipase A in Saccharomyces cerevisiae by translational fusion to the Pir4 cell wall protein
Motamed_2008_Eur.J.Clin.Pharmacol_64_1043 Dose-response effect of serum butyrylcholinesterase activity after clinical doses of pancuronium
Mulcahy_2008_Inorg.Chem_47_5030 Solid-phase synthesis of tris-heteroleptic ruthenium(II) complexes and application to acetylcholinesterase inhibition
Musilek_2008_Anal.Bioanal.Chem_391_367 RP-HPLC determination of the lipophilicity of bispyridinium reactivators of acetylcholinesterase bearing a but-2-ene connecting linker
Musilek_2008_Bioorg.Med.Chem_16_8218 Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase
Myhrer_2008_Pharmacol.Biochem.Behav_89_633 Antiparkinson drugs used as prophylactics for nerve agents: studies of cognitive side effects in rats
Nemukhin_2008_J.Mol.Model_14_409 Characterization of a complete cycle of acetylcholinesterase catalysis by ab initio QM\/MM modeling
Nguyen_2008_Ecotoxicol.Environ.Saf_71_314 Brain cholinesterase response in the snakehead fish (Channa striata) after field exposure to diazinon
Niaura_2008_J.Phys.Chem.B_112_4094 Probing of lipase activity at air\/water interface by sum-frequency generation spectroscopy
Niu_2008_Am.J.Physiol.Endocrinol.Metab_295_E1106 Metabolism of very-low-density lipoprotein and chylomicrons by streptozotocin-induced diabetic rat heart: effects of diabetes and lipoprotein preference
Nizri_2008_J.Neuroimmunol_203_12 Suppression of neuroinflammation and immunomodulation by the acetylcholinesterase inhibitor rivastigmine
Noureddine_2008_J.Biol.Chem_283_20722 Acetylcholinesterase associates differently with its anchoring proteins ColQ and PRiMA
Nukoolkarn_2008_Bioorg.Med.Chem_16_6560 Petrosamine, a potent anticholinesterase pyridoacridine alkaloid from a Thai marine sponge Petrosia n. sp
Nunes_2008_Neurosci.Lett_446_83 Transthyretin knockout mouse nerves have increased lipoprotein lipase and sphingolipid content following crush
Nyhlen_2008_Chembiochem_9_1968 Influence of delta-functional groups on the enantiorecognition of secondary alcohols by Candida antarctica lipase B
Okoye_2008_Trans.R.Soc.Trop.Med.Hyg_102_591 Characterisation of DDT, pyrethroid and carbamate resistance in Anopheles funestus from Obuasi, Ghana
Olkowicz_2008_J.Chem.Neuroanat_36_85 Thalamic nuclei in the opossum Monodelphis domestica
Oopik_2008_Eur.J.Neurol_15_246 Clinical and laboratory-reconfirmed myasthenia gravis: a population-based study
Oropesa_2008_Environ.Toxicol_23_285 Effect of long-term exposure to simazine on brain and muscle acetylcholinesterase activity of common carp (Cyprinus carpio)
Page_2008_Cell.Mol.Life.Sci_65_1220 Serine peptidases: classification, structure and function
Pan_2008_Diabet.Med_25_435 Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial
Pan_2008_Bioorg.Med.Chem.Lett_18_3790 Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors
Pardo_2008_Thyroid_18_783 Phenotypic variation among four family members with congenital hypothyroidism caused by two distinct thyroglobulin gene mutations
Pariente_2008_Pharmacoepidemiol.Drug.Saf_17_655 Prevalence of cholinesterase inhibitors in subjects with dementia in Europe
Park_2008_Neurosci.Lett_448_143 Galantamine reduces striatal degeneration in 3-nitropropionic acid model of Huntington's disease
Park_2008_Carcinogenesis_29_729 Interactions of acetylcholinesterase with caveolin-1 and subsequently with cytochrome c are required for apoptosome formation
Pasarica_2008_Stem.Cells_26_969 Adipogenic human adenovirus Ad-36 induces commitment, differentiation, and lipid accumulation in human adipose-derived stem cells
Pasquare_2008_Neurochem.Int_53_382 Diacylglyceride lipase activity in rod outer segments depends on the illumination state of the retina
Pelletier_2008_Endocrinology_149_6471 Mice lacking the thyroid hormone receptor-alpha gene spend more energy in thermogenesis, burn more fat, and are less sensitive to high-fat diet-induced obesity
Pena-Montes_2008_Appl.Microbiol.Biotechnol_78_603 Purification and biochemical characterization of a broad substrate specificity thermostable alkaline protease from Aspergillus nidulans
Pereira_2008_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_148_265 Acute effects of diflubenzuron on the freshwater fish Prochilodus lineatus
Perera_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_150_247 Polymorphism and partial characterization of digestive enzymes in the spiny lobster Panulirus argus
Perera_2008_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_151_250 Changes in digestive enzymes through developmental and molt stages in the spiny lobster, Panulirus argus
Perez-Martinez_2008_Atheroscler.Suppl_9_49 Influence of genetic factors in the modulation of postprandial lipemia
Petek_2008_Acta.Biochim.Pol_55_97 Tenocyclidine treatment in soman-poisoned rats--intriguing results on genotoxicity versus protection
Peter_2008_Neurotoxicol_29_335 Delayed-onset encephalopathy and coma in acute organophosphate poisoning in humans
Picco_2008_Vet.Res.Commun_32_401 Pharmacokinetics and pharmacodynamics of chlorpyrifos in male and female cattle after topical administration
Picollo_2008_Fitoterapia_79_271 Anticholinesterase and pediculicidal activities of monoterpenoids
Pinheiro_2008_Appl.Biochem.Biotechnol_146_203 Response surface methodology as an approach to determine optimal activities of lipase entrapped in sol-gel matrix using different vegetable oils
Pohanka_2008_J.Enzyme.Inhib.Med.Chem_23_781 Photometric microplate assay for estimation of the efficacy of paraoxon-inhibited acetylcholinesterase reactivation
Ponce_2008_J.Cell.Biochem_104_1342 Coexpression of osteogenic and adipogenic differentiation markers in selected subpopulations of primary human mesenchymal progenitor cells
Ponnappa_2008_Peptides_29_1893 INN-toxin, a highly lethal peptide from the venom of Indian cobra (Naja naja) venom-Isolation, characterization and pharmacological actions
Potumarthi_2008_Appl.Biochem.Biotechnol_151_700 Effect of aeration and agitation regimes on lipase production by newly isolated Rhodotorula mucilaginosa-MTCC 8737 in stirred tank reactor using molasses as sole production medium
Printes_2008_Ecotoxicol.Environ.Saf_71_519 Clonal variation in acetylcholinesterase biomarkers and life history traits following OP exposure in Daphnia magna
Pu_2008_Int.J.Oral.Maxillofac.Surg_37_567 Trapezius muscle innervation from the spinal accessory nerve and branches of the cervical plexus
Puntel_2008_Arch.Toxicol_82_755 Antioxidant properties of oxime 3-(phenylhydrazono) butan-2-one
Quintaneiro_2008_Chemosphere_71_1803 Transport and acclimation conditions for the use of an estuarine fish (Pomatoschistus microps) in ecotoxicity bioassays: effects on enzymatic biomarkers
Raldua_2008_Chemosphere_73_56 First evidence of polybrominated diphenyl ether (flame retardants) effects in feral barbel from the Ebro River basin (NE, Spain)
Reid_2008_J.Biol.Chem_283_13087 Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis
Reid_2008_J.Neural.Transm.(Vienna)_115_1437 Effects of cholinesterase inhibitors on rat nicotinic receptor levels in vivo and in vitro
Reiter_2008_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_873_86 Chromatographic resolution, characterisation and quantification of VX enantiomers in hemolysed swine blood samples
Rezg_2008_Toxicology_250_27 Caffeic acid attenuates malathion induced metabolic disruption in rat liver, involvement of acetylcholinesterase activity
Rizzo_2008_J.Med.Chem_51_2883 Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity
Robaszkiewicz_2008_Mech.Ageing.Dev_129_572 N-chloroamino acids cause oxidative protein modifications in the erythrocyte membrane
Rocksen_2008_Toxicology_250_32 An animal model to study health effects during continuous low-dose exposure to the nerve agent VX
Rodriguez-Perez_2008_Nucleic.Acids.Symp.Ser.(Oxf)__101 Preparation of nucleoside-carbohydrate phosphodiester prodrug analogues by chemoenzymatic procedure
Roh_2008_J.Appl.Microbiol_105_116 Isolation of a low-temperature adapted lipolytic enzyme from uncultivated micro-organism
Roh_2008_Ecotoxicol.Environ.Saf_71_483 Ecotoxicological evaluation of chlorpyrifos exposure on the nematode Caenorhabditis elegans
Roland_2008_Brain.Res_1234_116 Increasing hippocampal acetylcholine levels enhance behavioral performance in an animal model of diencephalic amnesia
Rouhani_2008_Lipids_43_793 HDL composition regulates displacement of cell surface-bound hepatic lipase
Roy_2008_J.Mol.Graph.Model_27_197 An investigation of structurally diverse carbamates for acetylcholinesterase (AChE) inhibition using 3D-QSAR analysis
Rubio_2008_Arq.Bras.Endocrinol.Metabol_52_1337 A molecular analysis and long-term follow-up of two siblings with severe congenital hypothyroidism carrying the IVS30+1G>T intronic thyroglobulin mutation
Rueda_2008_Neurosci.Lett_433_22 Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome
Sachana_2008_Toxicol.In.Vitro_22_1387 Inhibition of extension outgrowth in differentiating rat C6 glioma cells by chlorpyrifos and chlorpyrifos oxon: effects on microtubule proteins
Sagoo_2008_Am.J.Epidemiol_168_1233 Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis
Saint_2008_Presse.Med_37_1261 [Symptomatic antidementia drugs: methodological considerations and clinical relevance in the population]
Salas_2008_Mol.Pharmacol_74_1641 Nicotine relieves anxiogenic-like behavior in mice that overexpress the read-through variant of acetylcholinesterase but not in wild-type mice
Sanchis_2008_Appl.Microbiol.Biotechnol_81_387 Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates
Sandra_2008_J.Agric.Food.Chem_56_7488 Effect of interfacial protein cross-linking on the in vitro digestibility of emulsified corn oil by pancreatic lipase
Santos_2008_Pediatr.Surg.Int_24_715 Study of acetylcholinesterase activity in rectal suction biopsy for diagnosis of intestinal dysganglionoses: 17-year experience of a single center
Sardana_2008_Clin.Chem_54_1951 Emerging biomarkers for the diagnosis and prognosis of prostate cancer
Sarica_2008_Obesity.(Silver.Spring)_16_1579 Evaluation of urinary oxalate levels in patients receiving gastrointestinal lipase inhibitor
Saxena_2008_Protein.Expr.Purif_61_191 Developing procedures for the large-scale purification of human serum butyrylcholinesterase
Schaeffer_2008_Psychopharmacology.(Berl)_198_1 Cholinergic and glutamatergic alterations beginning at the early stages of Alzheimer disease: participation of the phospholipase A2 enzyme
Schilke_2008_Biotechnol.Bioeng_101_9 Activation of immobilized lipase in non-aqueous systems by hydrophobic poly-DL-tryptophan tethers
Schoffelen_2008_Bioconjug.Chem_19_1127 Site-specific modification of Candida antarctica lipase B via residue-specific incorporation of a non-canonical amino acid
Scholey_2008_Psychopharmacology.(Berl)_198_127 An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers
Schreck_2008_Chemosphere_71_1832 Neurotoxic effect and metabolic responses induced by a mixture of six pesticides on the earthworm Aporrectodea caliginosa nocturna
Schweiger_2008_J.Biol.Chem_283_17211 The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding
Sekiya_2008_J.Lipid.Res_49_1829 Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis
Shah_2008_Biomed.Pharmacother_62_199 Current approaches in the treatment of Alzheimer's disease
Shan_2008_J.Anim.Sci_86_1781 Porcine adipose triglyceride lipase complementary deoxyribonucleic acid clone, expression pattern, and regulation by resveratrol
Sharma_2008_J.Psychopharmacol_22_162 Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by pitavastatin and donepezil
Sharma_2008_Pharmacol.Biochem.Behav_89_535 Exploitation of HIV protease inhibitor Indinavir as a memory restorative agent in experimental dementia
Shearer_2008_Prostaglandins.Leukot.Essent.Fatty.Acids_79_215 Lipoprotein lipase releases esterified oxylipins from very low-density lipoproteins
Shen_2008_Bioorg.Med.Chem_16_7646 2-Phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors: a study on the importance of modifications at the side chain on the activity
Shin_2008_Exp.Cell.Res_314_3048 Lymphatic-specific expression of dipeptidyl peptidase IV and its dual role in lymphatic endothelial function
Shishido_2008_Bioorg.Med.Chem_16_7193 Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist 'CJ-17,493'
Shiu_2008_Atherosclerosis_198_441 Type 2 diabetes mellitus and endothelial lipase
Silva_2008_Ecotoxicology_17_725 In vitro and in vivo effects of cadmium on cholinesterases in Nile tilapia fingerlings: implications for biomonitoring aquatic pollution
Silveyra_2008_Mol.Cell.Biol_28_2908 Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation
Simon_2008_J.Biol.Chem_283_9341 Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain
Sink_2008_J.Am.Geriatr.Soc_56_847 Dual use of bladder anticholinergics and cholinesterase inhibitors: long-term functional and cognitive outcomes
Siwicka_2008_J.Pineal.Res_45_40 The oxidation products of melatonin derivatives exhibit acetylcholinesterase and butyrylcholinesterase inhibitory activity
Skamnioti_2008_New.Phytol_180_711 Evolutionary history of the ancient cutinase family in five filamentous Ascomycetes reveals differential gene duplications and losses and in Magnaporthe grisea shows evidence of sub- and neo-functionalization
Sleat_2008_Mol.Genet.Metab_94_222 Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis
Slotkin_2008_Neurotoxicol.Teratol_30_433 Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model
Smith_2008_J.Biol.Chem_283_33536 Mapping of the hormone-sensitive lipase binding site on the adipocyte fatty acid-binding protein (AFABP). Identification of the charge quartet on the AFABP\/aP2 helix-turn-helix domain
Smith_2008_Australas.Psychiatry_16_433 Quality of life and cholinesterase inhibitors: a qualitative study of patients with Alzheimer's disease and their carers
Snellman_2008_Antonie.Van.Leeuwenhoek_94_621 Transesterification activity of a novel lipase from Acinetobacter venetianus RAG-1
Sole_2008_Sci.Total.Environ_402_306 Cholinesterases activities and lipid peroxidation levels in muscle from shelf and slope dwelling fish from the NW Mediterranean: its potential use in pollution monitoring
Sole_2008_Mar.Pollut.Bull_56_999 Esterases activities and lipid peroxidation levels in muscle tissue of the shanny Lipophrys pholis along several sites from the Portuguese Coast
Someya_2008_Naunyn.Schmiedebergs.Arch.Pharmacol_377_209 Pharmacological profile of ASP8497, a novel, selective, and competitive dipeptidyl peptidase-IV inhibitor, in vitro and in vivo
Sondhi_2008_Exp.Neurol_213_18 Survival advantage of neonatal CNS gene transfer for late infantile neuronal ceroid lipofuscinosis
Spanevello_2008_Neurochem.Res_33_1129 Effects in vitro of guanidinoacetate on adenine nucleotide hydrolysis and acetylcholinesterase activity in tissues from adult rats
Stafford_2008_J.Ethnopharmacol_119_513 Review on plants with CNS-effects used in traditional South African medicine against mental diseases
Starowicz_2008_Obesity.(Silver.Spring)_16_553 Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet
Stern_2008_Cell.Tissue.Res_333_333 Mixed cholinergic\/glutamatergic neuromuscular innervation of Onychophora: a combined histochemical\/electrophysiological study
Stoveken_2008_Angew.Chem.Int.Ed.Engl_47_3688 Bacterial acyltransferases as an alternative for lipase-catalyzed acylation for the production of oleochemicals and fuels
Stum_2008_Hum.Mol.Genet_17_3166 Evidence of a dosage effect and a physiological endplate acetylcholinesterase deficiency in the first mouse models mimicking Schwartz-Jampel syndrome neuromyotonia
Sultana_2008_J.Enzyme.Inhib.Med.Chem_23_877 Lipoxygenase inhibition by novel fatty acid ester from Annona squamosa seeds
Sultatos_2008_Toxicol.Appl.Pharmacol_230_390 Altered binding of thioflavin t to the peripheral anionic site of acetylcholinesterase after phosphorylation of the active site by chlorpyrifos oxon or dichlorvos
Sun_2008_Clin.Exp.Metastasis_25_765 CD26\/dipeptidyl peptidase IV regulates prostate cancer metastasis by degrading SDF-1\/CXCL12
Syed_2008_Clin.Exp.Metastasis_25_787 Acetylcholinesterase supports anchorage independence in colon cancer
Takac_2008_J.Ind.Microbiol.Biotechnol_35_1019 Effects of lipidic carbon sources on the extracellular lipolytic activity of a newly isolated strain of Bacillus subtilis
Takahashi_2008_Arterioscler.Thromb.Vasc.Biol_28_455 In vivo arterial lipoprotein lipase expression augments inflammatory responses and impairs vascular dilatation
Takakusagi_2008_Bioorg.Med.Chem_16_9837 Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool
Takashina_2008_J.Neural.Transm.(Vienna)_115_1027 MKC-231, a choline uptake enhancer: (2) Effect on synthesis and release of acetylcholine in AF64A-treated rats
Taniguchi_2008_J.Org.Chem_73_3875 Linker-oriented design of binaphthol derivatives for optical resolution using lipase-catalyzed reaction
Tanino_2008_Biopharm.Drug.Dispos_29_259 Enzymatic stability of 2'-ethylcarbonate-linked paclitaxel in serum and conversion to paclitaxel by rabbit liver carboxylesterase for use in prodrug\/enzyme therapy
Tapp_2008_J.Agric.Food.Chem_56_6623 Determination and isolation of a thioesterase from passion fruit (Passiflora edulis Sims) that hydrolyzes volatile thioesters
Tarrago_2008_Bioorg.Med.Chem_16_7516 Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor
Tasker_2008_Neurosci.Lett_442_297 Butyrylcholinesterase K variant associated with higher enzyme activity in the temporal cortex of elderly patients
Tateno_2008_Neuroradiology_50_723 Quantitative analysis of the effects of donepezil on regional cerebral blood flow in Alzheimer's disease by using an automated program, 3DSRT
Taylor_2008_J.Neurochem_106_1828 Cytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death
Taylor_2008_J.Ocul.Pharmacol.Ther_24_473 Alterations in autonomic function in the guinea pig eye following exposure to dichlorvos vapor
Tazoe_2008_Biochem.Biophys.Res.Commun_376_111 Induction of ABCA1 by overexpression of hormone-sensitive lipase in macrophages
Teller_2008_Biosens.Bioelectron_24_111 Development of a bifunctional sensor using haptenized acetylcholinesterase and application for the detection of cocaine and organophosphates
Tenorio-Laranga_2008_FEBS.J_275_4415 Characterization of membrane-bound prolyl endopeptidase from brain
Tharp_2008_Biochem.Biophys.Res.Commun_372_595 The cannabinoid CB1 receptor is expressed in pancreatic delta-cells
Thireau_2008_Free.Radic.Biol.Med_45_396 Increased heart rate variability in mice overexpressing the Cu\/Zn superoxide dismutase
Tian_2008_Biochem.Genet_46_677 Mapping and expression analysis of chicken NDRG1 and NDRG3 genes
Timchalk_2008_Neurotoxicol_29_428 Development of a physiologically based pharmacokinetic and pharmacodynamic model to determine dosimetry and cholinesterase inhibition for a binary mixture of chlorpyrifos and diazinon in the rat
Tiruchinapalli_2008_J.Neurochem_107_1529 Activity-dependent expression of ELAV\/Hu RBPs and neuronal mRNAs in seizure and cocaine brain
Toiyama_2008_J.Surg.Oncol_97_404 Serum immunosuppressive acidic protein reflects systemic deterioration of colorectal cancer patient condition
Tonova_2008_Biotechnol.Adv_26_516 Reversed micelle solvents as tools of enzyme purification and enzyme-catalyzed conversion
Torigoe_2008_Skeletal.Radiol_37_1153 Xanthoma of bone associated with lipoprotein lipase deficiency
Torres_2008_Appl.Biochem.Biotechnol_151_221 Production and purification of a solvent-resistant esterase from Bacillus licheniformis S-86
Tory_2008_Int.J.Pharm_358_219 Cyclosporine A and Rapamycin induce in vitro cholesteryl ester transfer protein activity, and suppress lipoprotein lipase activity in human plasma
Trepp_2008_Am.J.Physiol.Endocrinol.Metab_294_E1127 Effect of GH on human skeletal muscle lipid metabolism in GH deficiency
Triana-Baltzer_2008_Mol.Cell.Neurosci_39_74 Multiple cell adhesion molecules shaping a complex nicotinic synapse on neurons
Trimukhe_2008_Int.J.Biol.Macromol_43_422 Environment friendly crosslinked chitosan as a matrix for selective adsorption and purification of lipase of Aspergillus niger
Tsunekawa_2008_Behav.Brain.Res_190_224 Synergistic effects of selegiline and donepezil on cognitive impairment induced by amyloid beta (25-35)
Tumiatti_2008_J.Med.Chem_51_7308 Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer
Tyagi_2008_J.Neuroimmunol_205_51 Influence of LPS-induced neuroinflammation on acetylcholinesterase activity in rat brain
Udayabanu_2008_Brain.Res_1230_138 Nitric oxide associated with iNOS expression inhibits acetylcholinesterase activity and induces memory impairment during acute hypobaric hypoxia
Ueno_2008_Am.J.Physiol.Endocrinol.Metab_294_E1109 Cardiac overexpression of hormone-sensitive lipase inhibits myocardial steatosis and fibrosis in streptozotocin diabetic mice
Ueyama_2008_Toxicol.Lett_182_42 Effect of the organophosphorus pesticide diazinon on glucose tolerance in type 2 diabetic rats
Umegaki_2008_Int.Psychogeriatr_20_800 Discontinuation of donepezil for the treatment of Alzheimer's disease in geriatric practice
Unal_2008_Biochem.J_413_315 Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase Calpha activates binding of the C subunit of protein kinase A to the 3'-untranslated region of the lipoprotein lipase mRNA
Urbain_2008_Phytochem.Anal_19_514 Preparative isolation of closely-related xanthones from Gentianella amarella ssp. acuta by High-speed countercurrent chromatography
Urbain_2008_J.Nat.Prod_71_895 Xanthones from Gentianella amarella ssp. acuta with acetylcholinesterase and monoamine oxidase inhibitory activities
Valdivielso_2008_J.Diabetes.Complications_22_273 Association of the -250G\/A promoter polymorphism of the hepatic lipase gene with the risk of peripheral arterial disease in type 2 diabetic patients
Vale_2008_Exp.Biol.Med.(Maywood)_233_941 Current management of the cognitive dysfunction in Parkinson's disease: how far have we come?
van Deursen_2008_Mol.Cell.Endocrinol_294_37 Down-regulation of hepatic lipase expression by elevation of cAMP in human hepatoma but not adrenocortical cells
van Deursen_2008_Diabetologia_51_2078 Glucose increases hepatic lipase expression in HepG2 liver cells through upregulation of upstream stimulatory factors 1 and 2
van Lingen_2008_Arch.Dermatol.Res_300_561 Distribution of dipeptidyl-peptidase IV on keratinocytes in the margin zone of a psoriatic lesion: a comparison with hyperproliferation and aberrant differentiation markers
van Lingen_2008_Br.J.Dermatol_158_1264 CD26\/dipeptidyl-peptidase IV in psoriatic skin: upregulation and topographical changes
Vella_2008_Clin.Endocrinol.(Oxf)_69_737 The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study
Venkataraman_2008_Int.J.Dev.Neurosci_26_585 Protective role of melatonin on PCB (Aroclor 1,254) induced oxidative stress and changes in acetylcholine esterase and membrane bound ATPases in cerebellum, cerebral cortex and hippocampus of adult rat brain
Vieira_2008_Sci.Total.Environ_395_87 Acute effects of Benzo[a]pyrene, anthracene and a fuel oil on biomarkers of the common goby Pomatoschistus microps (Teleostei, Gobiidae)
Vignaud_2008_Cell.Tissue.Res_333_289 Genetic inactivation of acetylcholinesterase causes functional and structural impairment of mouse soleus muscles
Vlachos_2008_Clin.Biochem_41_818 The effect of the mode of delivery on the maternal-neonatal erythrocyte membrane acetylcholinesterase activity
Walker_2008_J.Ethnopharmacol_120_169 Antinociceptive activity of Mirabilis jalapa in mice
Wang_2008_Am.J.Physiol.Endocrinol.Metab_295_E1455 Role of lysosomal acid lipase in the intracellular metabolism of LDL-transported dehydroepiandrosterone-fatty acyl esters
Wang_2008_Anal.Chem_80_8477 Magnetic electrochemical immunoassays with quantum dot labels for detection of phosphorylated acetylcholinesterase in plasma
Wang_2008_J.Phys.Chem.B_112_3485 Theoretical modeling study for the phosphonylation mechanisms of the catalytic triad of acetylcholinesterase by sarin
Wang_2008_Mol.Genet.Metab_95_117 Lipolysis and the integrated physiology of lipid energy metabolism
Wang_2008_J.Neurochem_106_1594 Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia
Watt_2008_Mol.Endocrinol_22_1200 Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness
Weinberg_2008_Leukemia_22_2184 Apolipoprotein E genotype as a determinant of survival in chronic lymphocytic leukemia
Weinstein_2008_J.Biol.Chem_283_34511 Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice
Weissman_2008_Toxicol.Appl.Pharmacol_232_351 Therapy against organophosphate poisoning: the importance of anticholinergic drugs with antiglutamatergic properties
Wiacek_2008_Langmuir_24_7413 Effect of temperature on n-tetradecane emulsion in the presence of phospholipid DPPC and enzyme lipase or phospholipase A2
Wierdl_2008_Cancer.Gene.Ther_15_183 An improved human carboxylesterase for enzyme\/prodrug therapy with CPT-11
Williams_2008_Risk.Anal_28_1069 Modeling cholinesterase activity for human dietary risk assessment of carbamate insecticides
Wilson_2008_Brain.Res_1200_159 Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
Wolf_2008_J.Neurochem_107_96 Neurturin, a member of the glial cell line-derived neurotrophic factor family, affects the development of acetylcholinesterase-positive cells in a three-dimensional model system of retinogenesis
Wu_2008_Biomacromolecules_9_2921 Functionalized polycarbonate derived from tartaric acid: enzymatic ring-opening polymerization of a seven-membered cyclic carbonate
Wu_2008_Anim.Genet_39_564 Discovery of a SNP in exon 7 of the lipoprotein lipase gene and its association with fatness traits in native and Cherry Valley Peking ducks
Xiang_2008_Cell.Mol.Life.Sci_65_1768 Acetylcholinesterase in intestinal cell differentiation involves G2\/M cell cycle arrest
Xiao_2008_Circ.Res_103_159 Enhanced cellular uptake of remnant high-density lipoprotein particles: a mechanism for high-density lipoprotein lowering in insulin resistance and hypertriglyceridemia
Xu_2008_Neurosci_155_403 Polymorphisms of the lipoprotein lipase gene are associated with atherosclerotic cerebral infarction in the Chinese
Xu_2008_Biophys.J_95_2500 Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics
Xu_2008_Appl.Microbiol.Biotechnol_79_1035 Effect of folding factors in rescuing unstable heterologous lipase B to enhance its overexpression in the periplasm of Escherichia coli
Xu_2008_Appl.Microbiol.Biotechnol_81_79 Heterologous expression of lipase in Escherichia coli is limited by folding and disulfide bond formation
Xu_2008_J.Am.Soc.Mass.Spectrom_19_1849 Monitoring enzyme reaction and screening of inhibitors of acetylcholinesterase by quantitative matrix-assisted laser desorption\/ionization Fourier transform mass spectrometry
Yamaoka_2008_Biosci.Biotechnol.Biochem_72_1601 Isolation of a thermotolerant photosynthetic bacterium, Rhodobacter sphaeroides Strain, NAT, and its capacity for oil and chemical oxygen demand removal at high temperatures
Yamashita_2008_Am.J.Physiol.Endocrinol.Metab_295_E705 Cardiac metabolic compensation to hypertension requires lipoprotein lipase
Yan_2008_Appl.Microbiol.Biotechnol_78_431 Optimization for producing cell-bound lipase from Geotrichum sp. and synthesis of methyl oleate in microaqueous solvent
Yanagida_2008_Neurosci.Res_62_254 Synergistic effect of galantamine on nicotine-induced neuroprotection in hemiparkinsonian rat model
Yano_2008_Cancer.Sci_99_2309 Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myeloma
Yener_2008_Eur.J.Neurol_15_540 Event-related delta oscillatory responses of Alzheimer patients
Yonezawa_2008_Biochem.Biophys.Res.Commun_376_36 Regulation of hormone-sensitive lipase expression by saturated fatty acids and hormones in bovine mammary epithelial cells
Yu_2008_Exp.Toxicol.Pathol_59_415 Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E
Zaheer-ul_2008_J.Chem.Inf.Model_48_1092 Receptor-based modeling and 3D-QSAR for a quantitative production of the butyrylcholinesterase inhibitors based on genetic algorithm
Zarros_2008_Metab.Brain.Dis_23_255 Effects of fulminant hepatic encephalopathy on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na(+),K (+))- and Mg (2+)-ATPase: comparison of the enzymes' response to in vitro treatment with ammonia
Zhang_2008_Mar.Biotechnol.(NY)_10_612 Molecular cloning and expression of a cold-adapted lipase gene from an Antarctic deep sea psychrotrophic bacterium Pseudomonas sp. 7323
Zhang_2008_Cell.Mol.Life.Sci_65_1435 The JNK\/AP1\/ATF2 pathway is involved in H2O2-induced acetylcholinesterase expression during apoptosis
Zhang_2008_Biochem.Biophys.Res.Commun_372_650 Template enhanced activity of lipase accommodated in siliceous mesocellular foams
Zhao_2008_Anal.Chem_80_3769 Electrochemical identification of the property of peripheral nerve fiber based on a biocompatible polymer film via in situ incorporating gold nanoparticles
Zheng_2008_J.Agric.Food.Chem_56_11493 Enhancement in the synthesis of novel feruloyl lipids (feruloyl butyryl glycerides) by enzymatic biotransformation using response surface methodology
Zhou_2008_Chem.Commun.(Camb)__5806 Epoxy functionalised poly(epsilon-caprolactone): synthesis and application
Zhou_2008_J.Agric.Food.Chem_56_2708 Preparation, stabilization, and bioefficacy of beta-cyclodextrin inclusion compounds of chloramidophos
Zhou_2008_Bioorg.Med.Chem_16_8011 Design, synthesis, and acetylcholinesterase inhibitory activity of novel coumarin analogues
Zhu_2008_Clin.Chem_54_705 Effect of (R)-salsolinol and N-methyl-(R)-salsolinol on the balance impairment between dopamine and acetylcholine in rat brain: involvement in pathogenesis of Parkinson disease
Zoumpanioti_2008_Biotechnol.Lett_30_1627 Esterification reactions catalyzed by lipases immobilized in organogels: effect of temperature and substrate diffusion
Zugno_2008_Metab.Brain.Dis_23_189 Guanidinoacetate administration increases acetylcholinesterase activity in striatum of rats and impairs retention of an inhibitory avoidance task
Akiyama_2008_Am.J.Pathol_173_1349 CGI-58 is an alpha\/beta-hydrolase within lipid transporting lamellar granules of differentiated keratinocytes
Alva_2008_Psychiatry.(Edgmont)_5_27 Relative tolerability of Alzheimer's disease treatments
Augstein_2008_Diabetes.Obes.Metab_10_850 Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32\/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance
Chow_2008_Biologics_2_917 Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome
Daminov_2008_Lik.Sprava__57 [Effects of simvastatin therapy on the lipid blood spectrum and nitric oxide in patients with chronic glomerulonephritis]
Huang_2008_Zhonghua.Shi.Yan.He.Lin.Chuang.Bing.Du.Xue.Za.Zhi_22_458 [Protection effects of acetylcholinesterase inhibitors on apoptosis]
Kovar_2008_Physiol.Res_57_555 Lipoprotein lipase activity determined in vivo is lower in carriers of apolipoprotein A-V gene variants 19W and -1131C
Labar_2008_Amino.Acids_34_127 A MBP-FAAH fusion protein as a tool to produce human and rat fatty acid amide hydrolase: expression and pharmacological comparison
Lindi_2008_Nutr.Metab.Cardiovasc.Dis_18_88 The G-250A polymorphism in the hepatic lipase gene promoter is associated with changes in hepatic lipase activity and LDL cholesterol: The KANWU Study
Prokai_2008_Chromatographia_68_s101 Measurement of Acetylcholine in Rat Brain Microdialysates by LC - Isotope Dilution Tandem MS
Tokuriki_2008_PLoS.Comput.Biol_4_e1000002 How protein stability and new functions trade off
van Acker_2008_Atherosclerosis_200_161 High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants
van Loo_2008_FEBS.Lett_582_1581 Inactivation of epoxide hydrolase by catalysis-induced formation of isoaspartate
Ward_2008_Curr.Aging.Sci_1_140 An observational study of the needs and quality of life amongst patients in the treatment of Alzheimer's dementia with cholinesterase inhibitors
Xu_2008_Sheng.Li.Ke.Xue.Jin.Zhan_39_10 [Adipose triglyceride lipase regulates adipocyte lipolysis]
Yamamoto_2008_Plant.Signal.Behav_3_576 Subcellular localization of overexpressed maize AChE gene in rice plant
Zheng_2008_J.Comput.Aided.Mol.Des_22_661 Rational design of an enzyme mutant for anti-cocaine therapeutics
Berger_2008_Vet.Res.Commun_32_75 Effects of oral tetrachlorvinphos fly control (Equitrol) administration in horses: physiological and behavioural findings
Boston_2008_Int.J.Geriatr.Psychiatry_23_439 Developing a simple laboratory test for Alzheimer's disease: measuring acetylcholinesterase in saliva - a pilot study
Chen_2008_Physiol.Res_57_119 Compensatory recovery of vagal control of hemodynamics after unilateral vagotomy
Elmegeed_2008_Eur.J.Med.Chem_43_763 Synthesis and in vivo anti-mutagenic activity of novel melatonin derivatives
Heine_2008_Proc.Natl.Acad.Sci.U.S.A_105_20947 Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin\/neuroligin contacts
Jimenez-Gomez_2008_Nutr.Metab.Cardiovasc.Dis_18_173 The -250G\/A polymorphism in the hepatic lipase gene promoter influences the postprandial lipemic response in healthy men
Kadir_2008_Neurobiol.Aging_29_1204 PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD
Kelai_2008_Neuroreport_19_751 Nrxn3 upregulation in the globus pallidus of mice developing cocaine addiction
Kovacevic_2008_Biochim.Biophys.Acta_1783_1981 The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets
Lee_2008_J.Bacteriol_190_1638 A common virulence plasmid in biotype 2 Vibrio vulnificus and its dissemination aided by a conjugal plasmid
Lefevre_2008_Clin.Pharmacol.Ther_83_106 Pharmacokinetics and pharmacodynamics of the novel daily rivastigmine transdermal patch compared with twice-daily capsules in Alzheimer's disease patients
Liepelt_2008_Nervenarzt_79_36 [Treatment for dementia in parkinsonian syndromes. Efficacy of cholinesterase inhibitors]
Liu_2008_Bioresour.Technol_99_1616 Lipolytic activity of suspended and membrane immobilized lipase originating from indigenous Burkholderia sp. C20
Liu_2008_Appl.Microbiol.Biotechnol_81_551 A mutation upstream of an ATPase gene significantly increases magnetosome production in Magnetospirillum gryphiswaldense
Lu_2008_Mol.Biol.Rep_35_59 Expression of lipoprotein lipase associated with lung adenocarcinoma tissues
Lukaszewicz-Hussain_2008_Food.Chem.Toxicol_46_82 Subchronic intoxication with chlorfenvinphos, an organophosphate insecticide, affects rat brain antioxidative enzymes and glutathione level
Ma_2008_Biol.Pharm.Bull_31_1316 Expression of NDRG2 in clear cell renal cell carcinoma
Mach_2008_J.Appl.Toxicol_28_132 Delayed behavioral and endocrine effects of sarin and stress exposure in mice
Mahanta_2008_Bioresour.Technol_99_1729 Production of protease and lipase by solvent tolerant Pseudomonas aeruginosa PseA in solid-state fermentation using Jatropha curcas seed cake as substrate
Mans_2008_Insect.Biochem.Mol.Biol_38_42 Comparative sialomics between hard and soft ticks: implications for the evolution of blood-feeding behavior
Mir_2008_Lasers.Med.Sci_23_19 Photodynamic inhibition of acetylcholinesterase after two-photon excitation of copper tetrasulfophthalocyanine
Nagler_2008_Dig.Dis.Sci_53_62 Seizures in an Alzheimer's disease patient as a complication of colonoscopy premedication with meperidine
Okuda_2008_J.Histochem.Cytochem_56_175 Differential expression patterns of NDRG family proteins in the central nervous system
Park_2008_Clin.Chim.Acta_387_84 A quantitative analysis of N-myc downstream regulated gene 2 (NDRG 2) in human tissues and cell lysates by reverse-phase protein microarray
Qu_2008_Dev.Biol_317_486 Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish
Rosenblatt_2008_Int.J.Geriatr.Psychiatry_23_178 Acetylcholinesterase inhibitors in assisted living: patterns of use and association with retention
Sakayama_2008_Cancer.Chemother.Pharmacol_61_471 Effect of cortisol on cell proliferation and the expression of lipoprotein lipase and vascular endothelial growth factor in a human osteosarcoma cell line
Schuler_2008_Appl.Environ.Microbiol_74_1050 Characterization of a novel angular dioxygenase from fluorene-degrading Sphingomonas sp. strain LB126
Seok_2008_Ecotoxicol.Environ.Saf_71_245 Risk assessment of the organophosphate pesticides isazofos and pyraclofos using a 21-day dietary toxicity study in Japanese quail
Shen_2008_Neuroreport_19_927 Immunohistochemical detection of Ndrg2 in the mouse nervous system
Takeuchi_2008_No.To.Hattatsu_40_451 [Neurotransmission in developmental disorders]
Tirawongsaroj_2008_J.Biotechnol_133_42 Novel thermophilic and thermostable lipolytic enzymes from a Thailand hot spring metagenomic library
Wu_2008_Se.Pu_26_577 [A rapid multi-residual analysis for organophosphorus pesticides in the products of animal origin using gas chromatography coupled with accelerated solvent extraction and gel permeation chromatographic purification]
Yang_2008_J.Environ.Sci.Health.B_43_219 Hydrolysis and soil sorption of insecticide pyraclofos
Yao_2008_Acta.Biochim.Biophys.Sin.(Shanghai)_40_625 NDRG2: a Myc-repressed gene involved in cancer and cell stress
Zhai_2008_J.Proteome.Res_7_1675 Phosphoproteome analysis of Drosophila melanogaster embryos
Zhang_2008_Gene_417_5 Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter region
Liu_2008_Gen.Comp.Endocrinol_156_164 Overexpression of Drosophila juvenile hormone esterase binding protein results in anti-JH effects and reduced pheromone abundance
Mascini_2008_Anal.Chem_80_9150 Oligopeptides as mimic of acetylcholinesterase: from the rational design to the application in solid-phase extraction for pesticides
Rehberg_2008_Cell.Calcium_44_386 A new non-disruptive strategy to target calcium indicator dyes to the endoplasmic reticulum
Schafellner_2008_J.Insect.Physiol_54_916 Juvenile hormone esterase activity in the pupating and diapausing larvae of Sesamia nonagrioides
Tanaka_2008_Biochim.Biophys.Acta_1779_17 Transcriptional regulation of the human soluble epoxide hydrolase gene EPHX2
Trinkaus_2008_J.Neurochem_105_2535 Neural regulation of acetylcholinesterase-associated collagen Q in rat skeletal muscles
Walker_2008_Obesity.(Silver.Spring)_16_1983 Subcutaneous abdominal adipose tissue subcompartments: potential role in rosiglitazone effects
Kathiresan_2008_N.Engl.J.Med_358_1240 Polymorphisms associated with cholesterol and risk of cardiovascular events
Kim_2008_Circ.Res_103_252 Protein kinase D is a key regulator of cardiomyocyte lipoprotein lipase secretion after diabetes
Otyepka_2008_Proteins_70_707 Second step of hydrolytic dehalogenation in haloalkane dehalogenase investigated by QM\/MM methods
Ronchetti_2008_J.Hepatol_49_474 Severe steatohepatitis in a patient with a rare neutral lipid storage disorder due to ABHD5 mutation
Al-Faifi_2008_Theor.Appl.Genet_117_523 Exploiting synteny in Cucumis for mapping of Psm: a unique locus controlling paternal mitochondrial sorting
Alfinito_2008_Nanotechnology_19_065202 A network model to correlate conformational change and the impedance spectrum of single proteins
Aly_2008_Appl.Environ.Microbiol_74_3812 Two angular dioxygenases contribute to the metabolic versatility of dibenzofuran-degrading Rhodococcus sp. strain HA01
Bacquet_2008_Mamm.Genome_19_439 Epigenetic processes in a tetraploid mammal
Banik_2008_Proc.Natl.Acad.Sci.U.S.A_105_17273 Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary
Bosak_2008_J.Enzyme.Inhib.Med.Chem_23_521 Differentiation of EDTA-sensitive from EDTA-insensitive human serum esterases hydrolysing phenylacetate
Cronin_2008_J.Mol.Biol_383_627 Insights into the catalytic mechanism of human sEH phosphatase by site-directed mutagenesis and LC-MS\/MS analysis
Goto_2008_DNA.Res_15_39 Complete genome sequence of Finegoldia magna, an anaerobic opportunistic pathogen
Hayden_2008_Genomics_91_530 Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients
Klasson_2008_Mol.Biol.Evol_25_1877 Genome evolution of Wolbachia strain wPip from the Culex pipiens group
Li_2008_Chem.Biol_15_118 Nonribosomal biosynthesis of fusaricidins by Paenibacillus polymyxa PKB1 involves direct activation of a D-amino acid
Moralev_2008_Zh.Evol.Biokhim.Fiziol_44_488 [Comparative analysis of sensitivity of cholinesterase inhibitors by multidimensional statistical methods]
Moralev_2008_Zh.Evol.Biokhim.Fiziol_44_352 [Comparative analysis of sensitivity of cholinesterases of different origin to reversible bis-onium inhibitors]
Penkov_2008_Genetika_44_1148 [Expression of imprinted Igf2 and Peg1\/Mest genes in postimplantation parthenogenetic mouse embryos treated with transforming growth factor alpha in vitro]
Schoherr_2008_Eur.J.Med.Genet_51_322 No evidence for isolated imprinting mutations in the PEG1\/MEST locus in Silver-Russell patients
Simmons_2008_PLoS.Biol_6_e177 Population genomic analysis of strain variation in Leptospirillum group II bacteria involved in acid mine drainage formation
Traister_2008_Biochem.J_410_503 Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface
Coetzer_2008_Biochimie_90_336 Oligopeptidase B: a processing peptidase involved in pathogenesis
Ekici_2008_Protein.Sci_17_2023 Unconventional serine proteases: variations on the catalytic Ser\/His\/Asp triad configuration
Gutierrez_2008_Plant.Biol.(Stuttg)_10_398 A possible role of prolyl oligopeptidase during Linum usitatissimum (flax) seed development
Mori_2008_Biosci.Biotechnol.Biochem_72_1611 A metagenomic approach to the identification of UDP-glucose 4-epimerase as a menadione resistance protein
Nichols_2008_FEMS.Microbiol.Lett_284_52 Identification and transcriptional profiling of Pseudomonas putida genes involved in furoic acid metabolism
Pidot_2008_BMC.Genomics_9_462 Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones
Sattley_2008_J.Bacteriol_190_4687 The genome of Heliobacterium modesticaldum, a phototrophic representative of the Firmicutes containing the simplest photosynthetic apparatus
Vosmann_2008_Appl.Microbiol.Biotechnol_80_29 Preparation of lipophilic alkyl (hydroxy)benzoates by solvent-free lipase-catalyzed esterification and transesterification
Brown_2008_Biochemistry_47_5724 Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis
Jelani_2008_Clin.Genet_74_184 A novel deletion mutation in LIPH gene causes autosomal recessive hypotrichosis (LAH2)
Gill_2008_Angew.Chem.Int.Ed.Engl_47_1676 Optical detection of glucose and acetylcholine esterase inhibitors by H2O2-sensitive CdSe\/ZnS quantum dots
Diaz_2008_Chemistry_14_9261 Strength enhancement of nanostructured organogels through inclusion of phthalocyanine-containing complementary organogelator structures and in situ cross-linking by click chemistry
Mukherjee_2008_Appl.Opt_47_1543 Sub-parts-per-billion level detection of dimethyl methyl phosphonate (DMMP) by quantum cascade laser photoacoustic spectroscopy
Yair_2008_Crit.Rev.Biotechnol_28_265 Organophosphate degrading microorganisms and enzymes as biocatalysts in environmental and personal decontamination applications
Karvaly_2008_J.Appl.Toxicol_28_21 Application of in vivo microdialysis for studying the efficacy of protective preparations against sulfur mustard penetrating the skin
Haitina_2008_BMC.Neurosci_9_43 Expression profile of the entire family of Adhesion G protein-coupled receptors in mouse and rat
Kloss_2008_Biosens.Bioelectron_23_1473 Microcavity array (MCA)-based biosensor chip for functional drug screening of 3D tissue models
Solovei_2008_EMBO.Rep_9_228 A journey into the nucleus. Conference on Nuclear Structure and Dynamics
Luttge_2008_J.Exp.Bot_59_1503 Clusia: Holy Grail and enigma
de Melo_2008_Ecotoxicol.Environ.Saf_71_821 Hepatic alterations in the fish Rhamdia quelen contaminated with Folidol 600(R)
Thangudu_2008_BMC.Struct.Biol_8_55 Analysis on conservation of disulphide bonds and their structural features in homologous protein domain families
Crawford_2008_Bioorg.Chem_36_16 Starter unit specificity directs genome mining of polyketide synthase pathways in fungi
Crawford_2008_Chembiochem_9_1559 Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases
Geula_2008_J.Neuropathol.Exp.Neurol_67_309 Cholinergic neuronal and axonal abnormalities are present early in aging and in Alzheimer disease
Loerch_2008_PLoS.One_3_e3329 Evolution of the aging brain transcriptome and synaptic regulation
Nishimune_2008_J.Cell.Biol_182_1201 Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
Sann_2008_J.Neurosci_28_2366 Neurite outgrowth and in vivo sensory innervation mediated by a Ca(V)2.2-laminin beta 2 stop signal
Dutta_2008_Ecotoxicol.Environ.Saf_69_556 Detection of pesticide by polymeric enzyme electrodes
Hassel_2008_Neurochem.Int_53_193 High-affinity choline uptake and acetylcholine-metabolizing enzymes in CNS white matter. A quantitative study
Jara-Oseguera_2008_J.Gen.Physiol_132_547 Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums
Salazar_2008_Nat.Neurosci_11_255 A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic
Tanaka-Amino_2008_Eur.J.Pharmacol_590_444 ASP4,000, a novel, selective, dipeptidyl peptidase 4 inhibitor with antihyperglycemic activity
Los_2008_ACS.Chem.Biol_3_373 HaloTag: a novel protein labeling technology for cell imaging and protein analysis
Williams_2008_J.Pharmacol.Toxicol.Methods_57_138 Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases
London_2008_Biol.Cybern_99_393 Predicting the synaptic information efficacy in cortical layer 5 pyramidal neurons using a minimal integrate-and-fire model
Johnson_2008_Neuropsychol.Dev.Cogn.B.Aging.Neuropsychol.Cogn_15_129 Associative learning over trials activates the hippocampus in healthy elderly but not mild cognitive impairment
Trivedi_2008_Neuropsychologia_46_1667 fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: risk factors for Alzheimer's disease
Kawano_2008_Biol.Pharm.Bull_31_998 Alteration of gene expression induced by Silurus asotus lectin in Burkitt's lymphoma cells
Brand_2008_J.Neurochem_105_1325 Docosahexaenoic acid-dependent iron accumulation in oligodendroglia cells protects from hydrogen peroxide-induced damage
Morgan_2008_Toxicol.Res_24_137 Reproductive Toxicity Evaluation of Pestban Insecticide Exposure in Male and Female Rats
Azoulay_2008_Plant.Physiol_148_108 Citrus chlorophyllase dynamics at ethylene-induced fruit color-break: a study of chlorophyllase expression, posttranslational processing kinetics, and in situ intracellular localization
Aguedo_2008_J.Agric.Food.Chem_56_1757 Enrichment of anhydrous milk fat in polyunsaturated fatty acid residues from linseed and rapeseed oils through enzymatic interesterification
Hernandez-Martin_2008_Bioresour.Technol_99_277 Different enzyme requirements for the synthesis of biodiesel: Novozym 435 and Lipozyme TL IM
Weber_2008_J.Sep.Sci_31_1346 Supercritical fluid assisted, integrated process for the synthesis and separation of different lipid derivatives
Aurilia_2008_Gene_410_234 Microbial carbohydrate esterases in cold adapted environments
Benoit_2008_Biotechnol.Lett_30_387 Biotechnological applications and potential of fungal feruloyl esterases based on prevalence, classification and biochemical diversity
Smith_2008_Science_321_1304 An enzyme assembly line
Bitzopoulou_2008_Biochim.Biophys.Acta_1784_1226 Mutant forms of the extracellular domain of the human acetylcholine receptor gamma-subunit with improved solubility and enhanced antigenicity. The importance of the Cys-loop
Konstantakaki_2008_J.Mol.Graph.Model_26_1333 Model of the extracellular domain of the human alpha7 nAChR based on the crystal structure of the mouse alpha1 nAChR extracellular domain
Lopez-Raez_2008_Plant.Signal.Behav_3_963 Fine-tuning regulation of strigolactone biosynthesis under phosphate starvation
Xu_2008_Sci.Total.Environ_393_333 Occurrence and degradation characteristics of dibutyl phthalate (DBP) and di-(2-ethylhexyl) phthalate (DEHP) in typical agricultural soils of China
Zeng_2008_Appl.Microbiol.Biotechnol_80_899 Biodegradation of dimethyl phthalate by Sphingomonas sp. isolated from phthalic-acid-degrading aerobic granules
Tuvignon_2008_Anal.Biochem_383_289 Development of an indirect method for measuring porcine pancreatic lipase in human duodenal fluid
de Geus_2008_Biomacromolecules_9_752 Insights into the initiation process of enzymatic ring-opening polymerization from monofunctional alcohols using liquid chromatography under critical conditions
Raina_2008_J.Agric.Food.Chem_56_6594 New metabolites in the degradation of alpha- and gamma-hexachlorocyclohexane (HCH): pentachlorocyclohexenes are hydroxylated to cyclohexenols and cyclohexenediols by the haloalkane dehalogenase LinB from Sphingobium indicum B90A
Bat_2008_Biomacromolecules_9_3208 Trimethylene carbonate and epsilon-caprolactone based (co)polymer networks: mechanical properties and enzymatic degradation
Carstens_2008_J.Pharm.Sci_97_506 A mechanistic study on the chemical and enzymatic degradation of PEG-Oligo(epsilon-caprolactone) micelles
Dai_2008_Biomacromolecules_9_1883 Enzymatic preparation of novel thermoplastic di-block copolyesters containing poly[(R)-3-hydroxybutyrate] and poly(epsilon-caprolactone) blocks via ring-opening polymerization
Gomes_2008_J.Tissue.Eng.Regen.Med_2_243 Starch-poly(epsilon-caprolactone) and starch-poly(lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: structure, mechanical properties and degradation behaviour
Hofman_2008_Pharm.Res_25_2065 Photocytotoxicity of mTHPC (temoporfin) loaded polymeric micelles mediated by lipase catalyzed degradation
Latere_2008_Pharmazie_63_235 Spontaneously self-assembled micelles from poly(ethylene glycol)-b-poly(epsilon-caprolactone-co-trimethylene carbonate) for drug solubilization
Yeo_2008_J.Biomed.Mater.Res.B.Appl.Biomater_87_562 Customizing the degradation and load-bearing profile of 3D polycaprolactone-tricalcium phosphate scaffolds under enzymatic and hydrolytic conditions
Rodriguez_2008_Int.J.Food.Microbiol_121_92 Characterization of tannase activity in cell-free extracts of Lactobacillus plantarum CECT 748T
Smith_2008_J.Am.Chem.Soc_130_15361 Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle
Abe_2008_J.Immunol_181_7873 The secretion and uptake of lysosomal phospholipase A2 by alveolar macrophages
Groot_2008_Front.Zool_5_20 Host strain specific sex pheromone variation in Spodoptera frugiperda
Xie_2008_Phytochemistry_69_427 Isolation and identification of alectrol as (+)-orobanchyl acetate, a germination stimulant for root parasitic plants
Engler_2008_PLoS.One_3_e3647 A one pot, one step, precision cloning method with high throughput capability
van Es_2008_Nat.Genet_40_29 Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis
Bertram_2008_J.Am.Oil.Chem.Soc_85_47 Characterization of Lipases and Esterases from Metagenomes for Lipid Modification
Lin_2008_Asian.J.Chem_20_1217 Interaction mechanism between Pseudomonas species lipase and nitro compounds
Ramirez_2008_Appl.Biochem.Biotechnol_151_711 A new microplate screening method for the simultaneous activity quantification of feruloyl esterases, tannases, and chlorogenate esterases
Liang_2008_Appl.Microbiol.Biotechnol_80_183 Phthalates biodegradation in the environment
Shah_2008_Biotechnol.Adv_26_246 Biological degradation of plastics: a comprehensive review
Gupta_2008_Nat.Methods_5_939 Directed enzyme evolution via small and effective neutral drift libraries
Iyer_2008_J.Org.Chem_73_4819 The effects of sulfur substitution for the nucleophile and bridging oxygen atoms in reactions of hydroxyalkyl phosphate esters
Kim_2008_Biochemistry_47_9497 Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase
Yu_2008_J.Ethnopharmacol_119_252 Inhibition of Coix seed extract on fatty acid synthase, a novel target for anticancer activity
Brusehaber_2008_Tetrahedron.Asymmetry_19_730 Asymmetric synthesis of cis-3,5-diacetoxycyclopent-1-ene using metagenome-derived hydrolases
Hanson_2008_BMC.Neurosci_9 Suppl 3_S5 Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease
Li_2008_Appl.Environ.Microbiol_74_7482 Novel family of carbohydrate esterases, based on identification of the Hypocrea jecorina acetyl esterase gene
Darriet_2008_J.Am.Mosq.Control.Assoc_24_123 Laboratory evaluation of cyromazine against insecticide-susceptible and -resistant mosquito larvae
Munhenga_2008_Malar.J_7_247 Pyrethroid resistance in the major malaria vector Anopheles arabiensis from Gwave, a malaria-endemic area in Zimbabwe
Carolan_2008_J.Med.Chem_51_6400 Isosorbide-2-carbamate esters: potent and selective butyrylcholinesterase inhibitors
Lee_2008_Plant.J_54_452 Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1
Tsuda_2008_Plant._53_763 Interplay between MAMP-triggered and SA-mediated defense responses