2016

Yin_2016_Catal.Sci.Technol_6_6305 Green access to chiral Vince lactam in a buffer-free aqueous system using a newly identified substrate-tolerant (-)-gamma-lactamase
Hong_2016_J.Mol.Catal.B.Enzym_133_S337 Gene cloning and characterization of a psychrophilic phthalate esterase with organic solvent tolerance from an Arctic bacterium Sphingomonas glacialis PAMC 26605
Wongwatanapaiboon_2016_Biosci.Biotechnol.Biochem_80_2231 Cloning, expression, and characterization of Aureobasidium melanogenum lipase in Pichia pastoris
Dilokpimol_2016_Biotechnol.Biofuels_9_231 Diversity of fungal feruloyl esterases: updated phylogenetic classification, properties, and industrial applications
Wang_2016_Appl.Biochem.Biotechnol_180_1196 Functional Characterization of a Robust Marine Microbial Esterase and Its Utilization in the Stereo-Selective Preparation of Ethyl (S)-3-Hydroxybutyrate
Wang_2016_Chin.J.Catal_37_1396 Characterization of a novel marine microbial esterase and its use to make D-methyl lactate
Yu_2016_BMC.Genomics_17_654 Seminal fluid protein genes of the brown planthopper, Nilaparvata lugens
Li_2016_J.Biotechnol_228_30 Cloning and characterization of a novel lipase from Stenotrophomonas maltophilia GS11: The first member of a new bacterial lipase family XVI
Flaugnatti_2016_Mol.Microbiol_99_1099 A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery
Tomihama_2016_Genome.Announc_4_e00062 Draft Genome Sequences of Streptomyces scabiei S58, Streptomyces turgidiscabies T45, and Streptomyces acidiscabies a10, the Pathogens of Potato Common Scab, Isolated in Japan
de Saint Germain_2016_Nat.Chem.Biol_12_787 An histidine covalent receptor and butenolide complex mediates strigolactone perception
Bi_2016_Sci.Rep_6_21162 A Biotin Biosynthesis Gene Restricted to Helicobacter
Iwata_2016_J.Biosci.Bioeng_122_140 Re-characterization of mono-2-ethylhexyl phthalate hydrolase belonging to the serine hydrolase family
Petrovskaya_2016_FEMS.Microbiol.Ecol_92_ Expression and characterization of a new esterase with GCSAG motif from a permafrost metagenomic library
Ye_2016_Catal.Commun_87_32 Directed modification of a novel epoxide hydrolase from Phaseolus vulgaris to improve its enantioconvergence towards styrene epoxides
Zarafeta_2016_Sci.Rep_6_38886 Metagenomic mining for thermostable esterolytic enzymes uncovers a new family of bacterial esterases
Tao_2016_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_203_100 Cloning of two carboxylesterase cDNAs from the swimming crab Portunus trituberculatus: Molecular evidences for their putative roles in methyl farnesotae degradation
Kono_2016_Mol.Ecol.Resour_16_662 Evaluation of the impact of RNA preservation methods of spiders for de novo transcriptome assembly
You_2016_Parasit.Vectors_9_328 Functional characterisation of Schistosoma japonicum acetylcholinesterase
Cruz_2016_Gigascience_5_29 Genome sequence of the olive tree, Olea europaea
Hashimoto_2016_Nat.Commun_7_12808 Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein
Anantharaman_2016_Nat.Commun_7_13219 Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system
Grijseels_2016_Sci.Rep_6_35112 Penicillium arizonense, a new, genome sequenced fungal species, reveals a high chemical diversity in secreted metabolites
Moore_2016_Genome.Biol.Evol_8_3297 Draft Genome Sequence of an Aflatoxigenic Aspergillus Species, A. bombycis
Hunt_2016_Nat.Genet_48_299 The genomic basis of parasitism in the Strongyloides clade of nematodes
Small_2016_Mol.Ecol_25_1465 Population genomics of the filarial nematode parasite Wuchereria bancrofti from mosquitoes
Niehaus_2016_Genome.Biol.Evol_8_3574 Comparative Omics of the Fusarium fujikuroi Species Complex Highlights Differences in Genetic Potential and Metabolite Synthesis
Session_2016_Nature_538_336 Genome evolution in the allotetraploid frog Xenopus laevis
Sayed_2016_J.Biotechnol_221_62 Selective oxidation of trimethylolpropane to 2,2-bis(hydroxymethyl)butyric acid using growing cells of Corynebacterium sp. ATCC 21245
Yan_2016_MBio_7_e02104 Strain Prioritization and Genome Mining for Enediyne Natural Products
Butterfield_2016_PeerJ_4_E2687 Proteogenomic analyses indicate bacterial methylotrophy and archaeal heterotrophy are prevalent below the grass root zone
Ercibengoa_2016_Antonie.Van.Leeuwenhoek_109_653 Nocardia donostiensis sp. nov., isolated from human respiratory specimens
Al-Wathiqui_2016_Sci.Rep_6_38556 Molecular characterization of firefly nuptial gifts: a multi-omics approach sheds light on postcopulatory sexual selection
Deng_2016_Appl.Biochem.Biotechnol_180_228 Functional Characterization of a Novel Dactylosporangium Esterase and Its Utilization in the Asymmetric Synthesis of (R)-Methyl Mandelate
Tong_2016_Biotechnol.Appl.Biochem_63_471 Characterization of a new sn-1,3-regioselective triacylglycerol lipase from Malbranchea cinnamomea
De Santi_2016_PLoS.One_11_e0159345 Biochemical Characterization of a Family 15 Carbohydrate Esterase from a Bacterial Marine Arctic Metagenome
Hagstrom_2017_Arch.Toxicol_91_2837 Planarian cholinesterase: in vitro characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity and reactivation
Hagstrom_2016_Regeneration.(Oxf)_3_65 Planarian brain regeneration as a model system for developmental neurotoxicology
Yoshida_2016_Science_351_1196 A bacterium that degrades and assimilates poly(ethylene terephthalate)
Tanasupawat_2016_Int.J.Syst.Evol.Microbiol_66_2813 Ideonella sakaiensis sp. nov., isolated from a microbial consortium that degrades poly(ethylene terephthalate)
Yang_2016_Science_353_759 Comment on A bacterium that degrades and assimilates poly(ethylene terephthalate)
Yoshida_2016_Science_353_759 Response to Comment on A bacterium that degrades and assimilates poly(ethylene terephthalate)
Rauwerdink_2016_Mol.Biol.Evol_33_971 Evolution of a Catalytic Mechanism
Cao_2016_Appl.Biochem.Biotechnol_180_210 Functional Characterization of a Novel Marine Microbial Esterase and its Utilization in the Enantioselective Preparation of (R)-Methyl 2-Chloropropionate
Lee_2016_Front.Microbiol_7_218 Isolation and Characterization of a Novel Cold-Adapted Esterase, MtEst45, from Microbulbifer thermotolerans DAU221
Wang_2016_Bull.Entomol.Res_106_615 Expression and characterization of a lipase-related protein in the malpighian tubules of the Chinese oak silkworm, Antheraea pernyi
de Oliveira_2016_Int.J.Biol.Macromol_89_569 Epoxide hydrolase of Trichoderma reesei: Biochemical properties and conformational characterization
Koseki_2016_J.Mol.Catal.B.Enzym_133_S560 An unusual feruloyl esterase from Aspergillus oryzae: two tryptophan residues play a crucial role for the activity
Chekan_2016_J.Am.Chem.Soc_138_16452 Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates
Yuan_2016_Biotechnol.Appl.Biochem_63_41 Screening and characterization of a thermostable lipase from marine Streptomyces sp. strain W007
Liu_2016_Sci.Rep_6_38137 Engineering of a thermostable esterase Est816 to improve its quorum-quenching activity and the underlying structural basis
Yan_2016_Appl.Environ.Microbiol_82_6748 Facilitating the Evolution of Esterase Activity from a Promiscuous Enzyme (Mhg) with Catalytic Functions of Amide Hydrolysis and Carboxylic Acid Perhydrolysis by Engineering the Substrate Entrance Tunnel
Fage_2016_Angew.Chem.Int.Ed.Engl_55_12717 Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase
Xu_2016_Sci.Rep_6_31386 Structural basis of unique ligand specificity of KAI2-like protein from parasitic weed Striga hermonthica
Meng_2016_PLoS.One_11_e0158011 Identification and Biochemical Properties of Two New Acetylcholinesterases in the Pond Wolf Spider (Pardosa pseudoannulata)
Jin_2016_Appl.Microbiol.Biotechnol_100_9163 Comparative genomic analysis identified a mutation related to enhanced heterologous protein production in the filamentous fungus Aspergillus oryzae
Huang_2016_Sci.Rep_6_28550 Structural insights of a hormone sensitive lipase homologue Est22
Oh_2016_J.Biol.Chem_291_15185 Structural Insights into an Oxalate-producing Serine Hydrolase with an Unusual Oxyanion Hole and Additional Lyase Activity
Gruninger_2016_Biochem.J_473_839 Contributions of a unique beta-clamp to substrate recognition illuminates the molecular basis of exolysis in ferulic acid esterases
Drake_2016_Nature_529_235 Structures of two distinct conformations of holo-non-ribosomal peptide synthetases
Perz_2016_Biotechnol.Bioeng_113_1024 Hydrolysis of synthetic polyesters by Clostridium botulinum esterases
Tolzer_2016_FEBS.Lett_590_174 A novel esterase subfamily with alpha\/beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases
Li_2016_J.Mol.Catal.B.Enzym_125_75 Rational selection of circular permutation sites in characteristic regions of the alpha\/beta-hydrolase fold enzyme RhEst1
Luan_2016_Ind.Eng.Chem.Res_55_12167 Dramatically Improved Performance of an Esterase for Cilastatin Synthesis by Cap Domain Engineering
De Santi_2016_Extremophiles_20_323 Biochemical characterization and structural analysis of a new cold-active and salt-tolerant esterase from the marine bacterium Thalassospira sp
Perz_2016_N.Biotechnol_33_295 Substrate specificities of cutinases on aliphatic-aromatic polyesters and on their model substrates
Shi_2016_Sci.Rep_6_18646 Functional Analysis of Esterase TCE2 Gene from Tetranychus cinnabarinus (Boisduval) involved in Acaricide Resistance
Kelle_2016_Biotechnol.Appl.Biochem_63_852 Heterologous production of a feruloyl esterase from Pleurotus sapidus synthesizing feruloyl-saccharide esters
Truongvan_2016_Biochemistry_55_3542 Flexibility and Stability Trade-Off in Active Site of Cold-Adapted Pseudomonas mandelii Esterase EstK
Wei_2016_Biotechnol.Bioeng_113_1658 Engineered bacterial polyester hydrolases efficiently degrade polyethylene terephthalate due to relieved product inhibition
Barth_2016_Biotechnol.J_11_1082 A dual enzyme system composed of a polyester hydrolase and a carboxylesterase enhances the biocatalytic degradation of polyethylene terephthalate films
Grigoraki_2016_Insect.Biochem.Mol.Biol_74_61 Functional and immunohistochemical characterization of CCEae3a, a carboxylesterase associated with temephos resistance in the major arbovirus vectors Aedes aegypti and Ae. albopictus
Wang_2016_J.Biomol.Struct.Dyn_34_749 Exploration of the chlorpyrifos escape pathway from acylpeptide hydrolases using steered molecular dynamics simulations
Rittiroongrad_2016_PLoS.One_11_e0168791 Agrobacterium tumefaciens estC, Encoding an Enzyme Containing Esterase Activity, Is Regulated by EstR, a Regulator in the MarR Family
Wittenborn_2016_J.Biol.Chem_291_25264 Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator
Engdahl_2016_J.Med.Chem_59_9409 Discovery of Selective Inhibitors Targeting Acetylcholinesterase 1 from Disease-Transmitting Mosquitoes
Kim_2016_Plant.J_85_758 Molecular and biochemical characterizations of the monoacylglycerol lipase gene family of Arabidopsis thaliana
Zapata_2016_Proc.Natl.Acad.Sci.U.S.A_113_E4052 Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms
Gharat_2016_PLoS.One_11_e0163485 Transcriptome Analysis of the Response to NaCl in Suaeda maritima Provides an Insight into Salt Tolerance Mechanisms in Halophytes
Yao_2016_Nature_536_469 DWARF14 is a non-canonical hormone receptor for strigolactone
Jakobson_2016_New.Phytol_211_614 BODYGUARD is required for the biosynthesis of cutin in Arabidopsis
Vijayakumar_2016_Plant.Physiol_170_180 The Arabidopsis ABHD11 Mutant Accumulates Polar Lipids in Leaves as a Consequence of Absent Acylhydrolase Activity
Sayer_2016_Sci.Rep_6_25542 Structural and biochemical characterisation of Archaeoglobus fulgidus esterase reveals a bound CoA molecule in the vicinity of the active site
Upadhyay_2016_Cell.Rep_14_2511 Subcellular Compartmentalization and Trafficking of the Biosynthetic Machinery for Fungal Melanin
Hu_2016_J.Biotechnol_236_152 Kinetic resolution of racemic styrene oxide at a high concentration by recombinant Aspergillus usamii epoxide hydrolase in an n-hexanol\/buffer biphasic system
Shirke_2016_Proteins_84_60 Toward rational thermostabilization of Aspergillus oryzae cutinase: Insights into catalytic and structural stability
Espinosa-Luna_2016_Mol.Biotechnol_58_37 Gene Cloning and Characterization of the Geobacillus thermoleovorans CCR11 Carboxylesterase CaesCCR11, a New Member of Family XV
Huang_2016_Appl.Biochem.Biotechnol_180_1467 Functional Characterization of a Marine Bacillus Esterase and its Utilization in the Stereo-Selective Production of D-Methyl Lactate
Khaleghinejad_2016_J.Genet.Eng.Biotechnol_14_83 Study the effect of F17S mutation on the chimeric Bacillus thermocatenulatus lipase
Malik_2016_Sci.Rep_6_38469 RNAi-mediated mortality of the whitefly through transgenic expression of double-stranded RNA homologous to acetylcholinesterase and ecdysone receptor in tobacco plants
Vekiru_2016_World.Mycotoxin.J_9_353 Isolation and characterisation of enzymatic zearalenone hydrolysis reaction products
Xu_2016_ACS.Catal_6_7657 Enhanced alpha-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering
Xiang_2016_Microbiol.Res_193_48 High-level expression of a ZEN-detoxifying gene by codon optimization and biobrick in Pichia pastoris
Wang_2016_Arch.Insect.Biochem.Physiol_93_110 Expression and effects of mutant Bombyx mori acetylcholinesterase 1 in BmN Cells
Wang_2016_Pestic.Biochem.Physiol_129_1 Effects of mutations on the structure and function of silkworm type 1 acetylcholinesterase
Jyoti_2016_Vet.Parasitol_216_108 Multiple mutations in the acetylcholinesterase 3 gene associated with organophosphate resistance in Rhipicephalus (Boophilus) microplus ticks from Punjab, India
Gui_2016_Mol.Cell.Probes_30_61 Association studies on the bovine lipoprotein lipase gene polymorphism with growth and carcass quality traits in Qinchuan cattle
Gui_2016_Genet.Mol.Res_15_ Polymorphisms in the LPL gene and their association with growth traits in Jiaxian cattle
Shu_2016_BMC.Biotechnol_16_38 Cell-bound lipases from Burkholderia sp. ZYB002: gene sequence analysis, expression, enzymatic characterization, and 3D structural model
Han_2016_Ecotoxicology_25_835 ace-3 plays an important role in phoxim resistance in Caenorhabditis elegans
Park_2016_ACS.Catal_6_7458 Structural and Experimental Evidence for the Enantiomeric Recognition toward a Bulky sec-Alcohol by Candida antarctica Lipase B
Strzelczyk_2016_Acta.Biochim.Pol_63_103 Crystal and molecular structure of hexagonal form of lipase B from Candida antarctica
Drozdz_2016_Chem.Commun.(Camb)_52_1230 Chemo-enzymatic Baeyer-Villiger oxidation of 4-methylcyclohexanone via kinetic resolution of racemic carboxylic acids: direct access to enantioenriched lactone
Jan_2016_Biochim.Biophys.Acta_1864_187 Elucidation of a key position for acyltransfer activity in Candida parapsilosis lipase\/acyltransferase (CpLIP2) and in Pseudozyma antarctica lipase A (CAL-A) by rational design
Point_2016_Eur.J.Med.Chem_123_834 Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis
Rodrigues_2016_Bioresour.Technol_218_1224 Biodiesel production from crude jatropha oil catalyzed by immobilized lipase\/acyltransferase from Candida parapsilosis in aqueous medium
Carlucci_2016_Protein.Sci_25_877 Biochemical characterization of two haloalkane dehalogenases: DccA from Caulobacter crescentus and DsaA from Saccharomonospora azurea
Nurizzo_2016_Acta.Crystallogr.D.Struct.Biol_72_966 RoboDiff: combining a sample changer and goniometer for highly automated macromolecular crystallography experiments
Wang_2016_Arch.Insect.Biochem.Physiol_93_129 Molecular characterization of two acetylcholinesterase genes from the rice leaffolder, Cnaphalocrocis medinalis (Lepidoptera: pyralidae)
Johnson_2016_Pest.Manag.Sci_72_481 Insecticide resistance alleles in wetland and residential populations of the West Nile virus vector Culex pipiens in New Jersey
Toumi_2016_J.Environ.Sci.Health.B__1 Effect of carbaryl (carbamate insecticide) on acetylcholinesterase activity of two strains of Daphnia magna (Crustacea, Cladocera)
Huber_2016_J.Biomed.Sci_23_83 Using the social amoeba Dictyostelium to study the functions of proteins linked to neuronal ceroid lipofuscinosis
Sharifkhodaei_2016_J.Cell.Sci_129_1477 The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184
Becker_2016_PLoS.Genet_12_e1005961 Cell-Autonomous and Non-cell-autonomous Function of Hox Genes Specify Segmental Neuroblast Identity in the Gnathal Region of the Embryonic CNS in Drosophila
Shepherd_2016_J.Comp.Neurol_524_2677 Postembryonic lineages of the Drosophila ventral nervous system: Neuroglian expression reveals the adult hemilineage associated fiber tracts in the adult thoracic neuromeres
Miller_2016_J.Biol.Chem_291_22559 Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-like Proteins Support a Highly Dynamic Domain Architecture
Choi_2016_FEMS.Microbiol.Lett_363_ Increased expression of genes involved in uptake and degradation of murein tripeptide under nitrogen starvation in Escherichia coli
Farberg_2016_Biochem.Biophys.Rep_7_415 The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis
Jallouli_2016_Int.J.Biol.Macromol_94_61 Efficient heterologous expression of Fusarium solani lipase, FSL2, in Pichia pastoris, functional characterization of the recombinant enzyme and molecular modeling
Hu_2016_Polym.Degrad.Stab_134_211 Enzymatic degradation of poly(butylene succinate) by cutinase cloned from Fusarium solani
Hikage_2016_Mol.Genet.Genomics_291_989 Allelic variants of the esterase gene W14\/15 differentially regulate overwinter survival in perennial gentian (Gentiana L.)
Gudiukaite_2016_Appl.Biochem.Biotechnol_178_654 Detection of Asp371, Phe375, and Tyr376 Influence on GD-95-10 Lipase Using Alanine Scanning Mutagenesis
Wahab_2016_Enzyme.Microb.Technol_93-94_174 Facile modulation of enantioselectivity of thermophilic Geobacillus zalihae lipase by regulating hydrophobicity of its Q114 oxyanion
Shi_2016_Biochemistry_55_6705 An Atypical alpha\/beta-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae
Li_2016_Int.J.Mol.Sci_17_ Bacterial Expression and Kinetic Analysis of Carboxylesterase 001D from Helicoverpa armigera
Miller_2016_Science_352_555 Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone
Obinata_2016_Eur.J.Cancer_57_39 Abhydrolase domain containing 2, an androgen target gene, promotes prostate cancer cell proliferation and migration
Manda_2016_Biosci.Rep_36_ Molecular characterization of human ABHD2 as TAG lipase and ester hydrolase
Zhao_2016_Cell.Rep_14_2872 alpha\/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes
Wei_2016_Proc.Natl.Acad.Sci.U.S.A_113_E2695 alpha\/beta-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors
Fisette_2016_Cell.Rep_17_1217 alpha\/beta-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility
Navia-Paldanius_2016_Eur.J.Pharm.Sci_93_253 Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha\/beta-hydrolase domain containing 11 (ABHD11)
Yang_2016_Tumour.Biol_37_1183 Using gastric juice lncRNA-ABHD11-AS1 as a novel type of biomarker in the screening of gastric cancer
Allgardsson_2016_Proc.Natl.Acad.Sci.U.S.A_113_5514 Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6
Goldenzweig_2016_Mol.Cell_63_337 Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
Macek Hrvat_2016_Chem.Biol.Interact_259_148 HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants
Kosak_2016_Sci.Rep_6_39495 Development of an in-vivo active reversible butyrylcholinesterase inhibitor
Dighe_2016_J.Med.Chem_59_7683 Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening
Kolar_2016_Biochemistry_55_4636 Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase
Xiao_2016_J.Biol.Chem_291_23224 A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis
Shi_2016_Biochem.Pharmacol_119_76 Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender
Shi_2016_Basic.Clin.Pharmacol.Toxicol_119_555 Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms
Wang_2016_Pharmacogenomics.J_16_220 CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors
Nzabonimpa_2016_Drug.Metab.Pers.Ther__ Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches
Shang_2016_Xenobiotica_46_393 Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells
Hines_2016_Drug.Metab.Dispos_44_959 Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny
Ohura_2016_Drug.Metab.Dispos_44_1890 Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
Fu_2016_Drug.Metab.Dispos_44_1313 Biotransformation Capacity of Carboxylesterase in Skin and Keratinocytes for the Penta-Ethyl Ester Prodrug of DTPA
Xu_2016_Sci.Rep_6_24277 Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4alpha and Protects Against Alcohol- and MCD diet-induced Liver Injury
Zhu_2016_Eur.J.Clin.Pharmacol_72_681 CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril
Zhao_2016_Eur.J.Clin.Pharmacol_72_1195 Impact of genetic polymorphisms related to clopidogrel or acetylsalicylic acid pharmacology on clinical outcome in Chinese patients with symptomatic extracranial or intracranial stenosis
Singh_2016_Biosci.Rep_36_ A novel live cell assay to measure diacylglycerol lipase alpha activity
Ogasawara_2016_Proc.Natl.Acad.Sci.U.S.A_113_26 Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Singh_2016_Biochemistry_55_2713 Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta
Li_2016_J.Med.Chem_59_6772 Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes
Wu_2016_ACS.Med.Chem.Lett_7_498 Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes
van Doremalen_2016_J.Virol_90_5499 Mapping the Specific Amino Acid Residues That Make Hamster DPP4 Functional as a Receptor for Middle East Respiratory Syndrome Coronavirus
Wilson_2016_Biol.Chem_397_837 Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches
Li_2016_Drug.Metab.Dispos_44_1341 Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane
Manickam_2016_Eur.J.Med.Chem_117_113 Discovery of enantioselectivity of urea inhibitors of soluble epoxide hydrolase
Shih_2016_Mol.Psychiatry_21_537 Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa
Hanif_2016_Am.J.Physiol.Regul.Integr.Comp.Physiol_311_R676 Deletion of soluble epoxide hydrolase enhances coronary reactive hyperemia in isolated mouse heart: role of oxylipins and PPARgamma
Xue_2016_ChemMedChem_11_497 Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry Exploration
Chiba_2016_J.Biol.Chem_291_14540 The Precise Structures and Stereochemistry of Trihydroxy-linoleates Esterified in Human and Porcine Epidermis and Their Significance in Skin Barrier Function: implication of an epoxide hydrolase in the transformation of linoleate
Yokoi_2016_J.Neurosci_36_6431 Identification of PSD-95 Depalmitoylating Enzymes
Gunawardane_2016_J.Biol.Chem_291_2799 Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism
Grumet_2016_J.Biol.Chem_291_17977 Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
Gokce_2016_J.Pediatr.Gastroenterol.Nutr_63_e39 The Key Clinical Manifestations of Lysosomal Acid Lipase Deficiency
Kong_2016_Oncol.Rep_36_1852 Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer
Slebe_2016_Nat.Commun_7_11199 FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth
Mysling_2016_Elife_5_e20958 The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
Vujic_2016_Oncotarget_7_7297 Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells
Won_2016_ACS.Chem.Biol_11_3374 Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2)
Ahn_2016_ACS.Chem.Biol_11_2529 Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism
Anunciado-Koza_2016_Biochimie_124_134 Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet
El Asmar_2016_J.Biol.Chem_291_5116 Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation
Cheung_2016_J.Invest.Dermatol_136_640 Psoriasis Skin Inflammation-Induced microRNA-26b Targets NCEH1 in Underlying Subcutaneous Adipose Tissue
Ross_2016_Arch.Biochem.Biophys_590_72 Interaction of the serine hydrolase KIAA1363 with organophosphorus agents: Evaluation of potency and kinetics
Yang_2016_Cell_164_805 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
Gong_2016_Oncotarget_7_68688 Constructing Bayesian networks by integrating gene expression and copy number data identifies NLGN4Y as a novel regulator of prostate cancer progression
Madan_2016_Oncotarget_7_12386 NOTUM is a potential pharmacodynamic biomarker of Wnt pathway inhibition
Tarver_2016_Bioorg.Med.Chem.Lett_26_1525 Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase
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Hwang_2016_Genome.Announc_4_e01226 Complete Genome Sequence of Alkaliphilus metalliredigens Strain QYMF, an Alkaliphilic and Metal-Reducing Bacterium Isolated from Borax-Contaminated Leachate Ponds
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Holbrook-Smith_2016_Nat.Chem.Biol_12_724 Small-molecule antagonists of germination of the parasitic plant Striga hermonthica
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Debuissy_2016_Biomacromolecules_17_4054 Enzymatic Synthesis of a Bio-Based Copolyester from Poly(butylene succinate) and Poly((R)-3-hydroxybutyrate): Study of Reaction Parameters on the Transesterification Rate
Bierwisch_2016_Toxicol.Lett_246_49 Kinetic analysis of interactions of amodiaquine with human cholinesterases and organophosphorus compounds
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Junaid_2016_PLoS.One_11_e0147761 Analyses of the Binding between Water Soluble C60 Derivatives and Potential Drug Targets through a Molecular Docking Approach
Nunes_2016_Cien.Saude.Colet_21_285 Characterization of Enzymatic profiles of Aedes aegypti strains from the State of Rio Grande do Norte, Brazil
Sofuoglu_2016_J.Dual.Diagn__0 Cognitive Function as a Trans-Diagnostic Treatment Target in Stimulant Use Disorders
Sumathi_2016_Environ.Toxicol.Pharmacol_42_99 l-Theanine alleviates the neuropathological changes induced by PCB (Aroclor 1254) via inhibiting upregulation of inflammatory cytokines and oxidative stress in rat brain
Wostmann_2016_PLoS.One_11_e0147193 Pilot Study on the Influence of Nutritional Counselling and Implant Therapy on the Nutritional Status in Dentally Compromised Patients
Zhou_2016_J.Insect.Sci_16_ Aphicidal Activity of Illicium verum Fruit Extracts and Their Effects on the Acetylcholinesterase and Glutathione S-transferases Activities in Myzus persicae (Hemiptera: Aphididae)
Akesson_2016_BMJ.Case.Rep_2016_ Lipoprotein lipase deficiency presenting with neonatal perianal abscesses
Campos_2016_Chemosphere_149_177 Are insect repellents toxic to freshwater insects? A case study using caddisflies exposed to DEET
Canak_2016_J.Mol.Microbiol.Biotechnol_25_403 Purification and Characterization of a Novel Cold-Active Lipase from the Yeast Candida zeylanoides
Fakhri-Bafghi_2016_Cell.J_17_740 Protective Effect of Selenium-Based Medicines on Toxicity of Three Common Organophosphorus Compounds in Human Erythrocytes In Vitro
Fan_2016_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_159_128 Spectroscopic studies on the inhibitory effects of ionic liquids on lipase activity
Hameed_2016_Bioorg.Chem_65_38 One-pot synthesis of tetrazole-1,2,5,6-tetrahydronicotinonitriles and cholinesterase inhibition: Probing the plausible reaction mechanism via computational studies
Nomura_2016_Chem.Biol.Interact_259_211 Lipases and their inhibitors in health and disease
Joosen_2016_Chem.Biol.Interact_259_115 Increasing nerve agent treatment efficacy by P-glycoprotein inhibition
Kratky_2016_Molecules_21_ Novel Cholinesterase Inhibitors Based on O-Aromatic N,N-Disubstituted Carbamates and Thiocarbamates
Liu_2016_J.Zhejiang.Univ.Sci.B_17_110 Developing antibodies from cholinesterase derived from prokaryotic expression and testing their feasibility for detecting immunogen content in Daphnia magna
Mantoani_2016_Molecules_21_ Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors
Mathpati_2016_Enzyme.Microb.Technol_84_1 Kinetic modeling and docking study of immobilized lipase catalyzed synthesis of furfuryl acetate
Muhammad_2016_Pharm.Biol__1 Phytochemicals from Dodonaea viscosa and their antioxidant and anticholinesterase activities with structure-activity relationships
Pasanisi_2016_Int.J.Cardiol_207_165 Severe cardiomyopathy in a young patient with complete deficiency of adipose triglyceride lipase due to a novel mutation in PNPLA2 gene
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Prabsattroo_2016_Oxid.Med.Cell.Longev_2016_5789857 Positive Modulation of Pink Nelumbo nucifera Flowers on Memory Impairment, Brain Damage, and Biochemical Profiles in Restraint Rats
Prokic_2016_Ecotoxicol.Environ.Saf_128_21 Antioxidative responses of the tissues of two wild populations of Pelophylax kl. esculentus frogs to heavy metal pollution
Reutgard_2016_Aquat.Toxicol_173_36 Linking sub-cellular biomarkers to embryo aberrations in the benthic amphipod Monoporeia affinis
Schulze_2016_Curr.Protoc.Immunol_112_22F 6 1 Culture, Expansion, and Differentiation of Murine Megakaryocytes from Fetal Liver, Bone Marrow, and Spleen
Tian_2016_Enzyme.Microb.Technol_84_32 First Novozym 435 lipase-catalyzed Morita-Baylis-Hillman reaction in the presence of amides
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Wang_2016_Pestic.Biochem.Physiol_127_1 Conifer flavonoid compounds inhibit detoxification enzymes and synergize insecticides
Yang_2016_Cell.Physiol.Biochem_38_696 Macrophage CGI-58 Attenuates Inflammatory Responsiveness via Promotion of PPARx03B3\; Signaling
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Alghazwi_2016_Curr.Med.Chem_23_360 Neuroprotective Activities of Marine Natural Products from Marine Sponges
Alout_2016_Heredity.(Edinb)_116_224 High chlorpyrifos resistance in Culex pipiens mosquitoes: strong synergy between resistance genes
Alter_2016_Can.J.Cardiol_32_217 From Heart Failure to Highly Unsaturated Fatty Acid Deficiency and Vice Versa: Bidirectional Heart and Liver Interactions
Badgujar_2016_Bioprocess.Biosyst.Eng_39_211 Enhanced biocatalytic activity of immobilized Pseudomonas cepacia lipase under sonicated condition
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Bancerz_2016_Biotechnol.Appl.Biochem_63_67 New alkaline lipase from Rhizomucor variabilis: Biochemical properties and stability in the presence of microbial EPS
Blocher_2016_J.Med.Chem_59_61 N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase\/Peroxisome Proliferator-Activated Receptor gamma Modulators
Blotnick-Rubin_2016_Neurosci_319_221 Exercise modulates synaptic acetylcholinesterase at neuromuscular junctions
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Carelli-Alinovi_2016_Biochimie_121_52 Involvement of acetylcholinesterase and protein kinase C in the protective effect of caffeine against beta-amyloid-induced alterations in red blood cells
Chalghmi_2016_Arch.Environ.Contam.Toxicol_70_241 Transcriptomic, Biochemical, and Histopathological Responses of the Clam Ruditapes decussatus from a Metal-Contaminated Tunis Lagoon
Chanda_2016_Mol.Psychiatry_21_169 Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking
Chiu_2016_Arterioscler.Thromb.Vasc.Biol_36_145 Cardiomyocyte VEGF Regulates Endothelial Cell GPIHBP1 to Relocate Lipoprotein Lipase to the Coronary Lumen During Diabetes Mellitus
Chlebek_2016_Fitoterapia_109_241 Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets
Chou_2016_Parkinsonism.Relat.Disord_23_45 Neuroimaging and clinical predictors of fatigue in Parkinson disease
Coetzee_2016_J.Ethnopharmacol_177_111 High-mesembrine Sceletium extract (Trimesemine) is a monoamine releasing agent, rather than only a selective serotonin reuptake inhibitor
Connelly_2016_J.Diabetes_8_63 Dipeptidyl peptidase-4 inhibition improves cardiac function in experimental myocardial infarction: Role of stromal cell-derived factor-1alpha
Cooper_2016_Age.Ageing_45_148 Observational cohort study: deprivation and access to anti-dementia drugs in the UK
Cross_2016_Drugs.Aging_33_37 Potentially Inappropriate Medications and Anticholinergic Burden in Older People Attending Memory Clinics in Australia
Cummings_2016_CNS.Neurosci.Ther_22_159 Role of Donepezil in the Management of Neuropsychiatric Symptoms in Alzheimer's Disease and Dementia with Lewy Bodies
Cwiklinska_2016_Chem.Phys.Lipids_195_63 Impact of phosphatidylcholine liposomes on the compositional changes of VLDL during lipoprotein lipase (LPL)-mediated lipolysis
de Hoyos-Alonso_2016_Neurologia_31_1 Estimated prevalence of dementia based on analysis of drug databases in the Region of Madrid (Spain)
Devamani_2016_J.Am.Chem.Soc_138_1046 Catalytic Promiscuity of Ancestral Esterases and Hydroxynitrile Lyases
Dewer_2016_Environ.Sci.Pollut.Res.Int_23_3086 Behavioral and metabolic effects of sublethal doses of two insecticides, chlorpyrifos and methomyl, in the Egyptian cotton leafworm, Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae)
Dolejsi_2016_J.Neurochem_136_503 Apolipoprotein E4 reduces evoked hippocampal acetylcholine release in adult mice
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Durieux_2016_J.Neurophysiol_115_5 Neuroligin-2 and the tightrope of excitation\/inhibition balance in the prefrontal cortex
Eimar_2016_Bone_84_131 Donepezil regulates energy metabolism and favors bone mass accrual
Fang_2016_Bioorg.Med.Chem_24_886 Ferulic acid-carbazole hybrid compounds: Combination of cholinesterase inhibition, antioxidant and neuroprotection as multifunctional anti-Alzheimer agents
Fang_2016_Mol.Neurobiol_53_270 Neuroligin-1 Knockdown Suppresses Seizure Activity by Regulating Neuronal Hyperexcitability
Fedoce_2016_Psychopharmacology.(Berl)_233_267 M3 muscarinic receptor in the ventral medial prefrontal cortex modulating the expression of contextual fear conditioning in rats
Fukuoka_2016_Appl.Microbiol.Biotechnol_100_1733 Control of enzymatic degradation of biodegradable polymers by treatment with biosurfactants, mannosylerythritol lipids, derived from Pseudozyma spp. yeast strains
Gao_2016_J.Pharmacol.Exp.Ther_356_645 Diisopropylfluorophosphate Impairs the Transport of Membrane-Bound Organelles in Rat Cortical Axons
Garcia-Garcia_2016_Life.Sci_145_274 Occupational pesticide exposure and adverse health effects at the clinical, hematological and biochemical level
Gauthier_2016_Aquat.Toxicol_170_377 Behavioural alterations from exposure to Cu, phenanthrene, and Cu-phenanthrene mixtures: linking behaviour to acute toxic mechanisms in the aquatic amphipod, Hyalella azteca
Gong_2016_Exp.Gerontol_74_21 Ameliorative effect of lotus seedpod proanthocyanidins on cognitive impairment and brain aging induced by d-galactose
Goomber_2016_Gene_576_237 Disruption of N terminus long range non covalent interactions shifted temp.opt 25 degrees C to cold: Evolution of point mutant Bacillus lipase by error prone PCR
Grabner_2016_J.Biol.Chem_291_913 Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation
Haslam_2016_J.Biomol.Screen_21_176 The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond
Hategan_2016_Gen.Hosp.Psychiatry_38_115 e1 Donepezil-associated manic episode with psychotic features: a case report and review of the literature
Hegazy_2016_Hum.Exp.Toxicol_35_251 Comparative study of cholinergic and oxidative stress biomarkers in brains of diabetic and hypercholesterolemic rats
Hegazy_2016_Planta.Med_82_138 Sesquiterpene Lactones from Cynara cornigera: Acetyl Cholinesterase Inhibition and In Silico Ligand Docking
Henderson_2016_Lancet.Neurol_15_249 Rivastigmine for gait stability in patients with Parkinson's disease (ReSPonD): a randomised, double-blind, placebo-controlled, phase 2 trial
Herrmann_2016_J.Am.Med.Dir.Assoc_17_142 A Randomized Placebo-Controlled Discontinuation Study of Cholinesterase Inhibitors in Institutionalized Patients With Moderate to Severe Alzheimer Disease
Higashino_2016_Psychopharmacology.(Berl)_233_521 Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice
Horsman_2016_Nat.Prod.Rep_33_183 Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?
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Ibarria_2016_J.Alzheimers.Dis_50_559 Beneficial Effects of an Integrated Psychostimulation Program in Patients with Alzheimer's Disease
Inoue_2016_Neuropharmacol_105_318 Nicotinic acetylcholine receptor-mediated GABAergic inputs to cholinergic interneurons in the striosomes and the matrix compartments of the mouse striatum
Iqbal_2016_Med.Chem_12_74 Biological Evaluation of Azomethine-dihydroquinazolinone Conjugates as Cancer and Cholinesterase Inhibitors
Jameel_2016_Chem.Biol.Drug.Des_87_21 Coumarin: A Privileged Scaffold for the Design and Development of Antineurodegenerative Agents
Jeon_2016_Environ.Sci.Pollut.Res.Int_23_1071 Chlorpyrifos-induced biomarkers in Japanese medaka (Oryzias latipes)
Ji_2016_Curr.Opin.Psychiatry_29_103 Pharmacotherapy for mental health problems in people with intellectual disability
Judge_2016_Chem.Biol.Interact_245_82 Mechanism for the acute effects of organophosphate pesticides on the adult 5-HT system
Julve_2016_Clin.Chim.Acta_455_134 Chylomicrons: Advances in biology, pathology, laboratory testing, and therapeutics
Kameshima_2016_Acta.Physiol.(Oxf)_216_203 Visceral adipose tissue-derived serine protease inhibitor augments acetylcholine-induced relaxation via the inhibition of acetylcholine esterase activity in rat isolated mesenteric artery
Karasova_2016_Neurotox.Res_29_267 Small Quaternary Inhibitors K298 and K524: Cholinesterases Inhibition, Absorption, Brain Distribution, and Toxicity
Kazui_2016_Drug.Metab.Dispos_44_115 Human Intestinal Raf Kinase Inhibitor Protein (RKIP) Catalyzes Prasugrel as a Bioactivation Hydrolase
Keri_2016_Chem.Biol.Drug.Des_87_101 New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease
Keyzer-Dekker_2016_Eur.J.Pediatr.Surg_26_100 Effectiveness of Rectal Suction Biopsy in Diagnosing Hirschsprung Disease
Khosrowbeygi_2016_Endocrine_51_245 Maternal circulating levels of some metabolic syndrome biomarkers in gestational diabetes mellitus
Kinoshita_2016_J.Lipid.Res_57_4 Glycosylphosphatidylinositol (GPI) Anchors: Biochemistry and Cell Biology: Introduction to a Thematic Review Series
Kinoshita_2016_J.Lipid.Res_57_6 Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling
Konigsbrugge_2016_Oncologist_21_252 Association Between Decreased Serum Albumin With Risk of Venous Thromboembolism and Mortality in Cancer Patients
Kovacic_2016_Protein.Eng.Des.Sel_29_65 Structural features determining thermal adaptation of esterases
Krueger_2016_J.Physiol_594_357 Neural influences on human intestinal epithelium in vitro
Kumar_2016_Brain_139_174 Amyloid-beta peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAbetaACs
Kuzma_2016_Phytother.Res_30_234 Taxodione and Extracts from Salvia austriaca Roots as Human Cholinesterase Inhibitors
Lai_2016_J.Comp.Neurol_524_807 Developmental expression of the neuroligins and neurexins in fragile X mice
Larsson_2016_Cell.Signal_28_204 Parathyroid hormone induces adipocyte lipolysis via PKA-mediated phosphorylation of hormone-sensitive lipase
Lawrence_2016_J.Cancer.Surviv_10_176 A study of donepezil in female breast cancer survivors with self-reported cognitive dysfunction 1 to 5 years following adjuvant chemotherapy
Lee_2016_J.Clin.Neurol_12_57 Treatment of Alzheimer's Disease with Repetitive Transcranial Magnetic Stimulation Combined with Cognitive Training: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Lee_2016_Toxicology_340_53 Repeated exposure to neurotoxic levels of chlorpyrifos alters hippocampal expression of neurotrophins and neuropeptides
Leomanni_2016_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_183-184_20 Mercury induced haemocyte alterations in the terrestrial snail Cantareus apertus as novel biomarker
Li_2016_Int.J.Biol.Macromol_86_119 Ionic liquids as novel solvents for biosynthesis of octenyl succinic anhydride-modified waxy maize starch
Li_2016_Environ.Toxicol_31_278 Physiological and molecular responses in brain of juvenile common carp (Cyprinus carpio) following exposure to tributyltin
Liu_2016_CNS.Neurosci.Ther_22_220 ST09, a Novel Thioester Derivative of Tacrine, Alleviates Cognitive Deficits and Enhances Glucose Metabolism in Vascular Dementia Rats
Loureiro_2016_Mol.Neurobiol_53_1065 Crosstalk Among Disrupted Glutamatergic and Cholinergic Homeostasis and Inflammatory Response in Mechanisms Elicited by Proline in Astrocytes
Luo_2016_Bioorg.Med.Chem_24_672 Design, synthesis and evaluation of novel 7-aminoalkyl-substituted flavonoid derivatives with improved cholinesterase inhibitory activities
Luo_2016_J.Ethnopharmacol_178_66 A systems pharmacology approach to decipher the mechanism of danggui-shaoyao-san decoction for the treatment of neurodegenerative diseases
Lv_2016_Mol.Genet.Genomics_291_309 Comparative transcriptome analyses of deltamethrin-susceptible and -resistant Culex pipiens pallens by RNA-seq
Makhaeva_2016_Bioorg.Med.Chem_24_1050 Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors
Matusica_2016_J.Cell.Sci_129_517 Inhibition of motor neuron death in vitro and in vivo by a p75 neurotrophin receptor intracellular domain fragment
Mertens_2016_Toxicol.Lett_244_161 A novel fluorogenic probe for the investigation of free thiols: Application to kinetic measurements of acetylcholinesterase activity
Misik_2016_Neurosci.Lett_612_261 Effects of novel tacrine-related cholinesterase inhibitors in the reversal of 3-quinuclidinyl benzilate-induced cognitive deficit in rats-Is there a potential for Alzheimer's disease treatment?
Miyazawa_2016_J.Nat.Med_70_282 Chemical composition, aroma evaluation, and inhibitory activity towards acetylcholinesterase of essential oils from Gynura bicolor DC
Mizoi_2016_Bioorg.Med.Chem.Lett_26_921 Synthesis and evaluation of atorvastatin esters as prodrugs metabolically activated by human carboxylesterases
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Murthy_2016_J.Pharmacol.Exp.Ther_356_720 Cocaine Hydrolase Gene Transfer Demonstrates Cardiac Safety and Efficacy against Cocaine-Induced QT Prolongation in Mice
Nasr_2016_Environ.Sci.Pollut.Res.Int_23_1852 Neuro and renal toxicity induced by chlorpyrifos and abamectin in rats : Toxicity of insecticide mixture
Nesakumar_2016_Bull.Environ.Contam.Toxicol_96_217 Evaluation of Inhibition Efficiency for the Detection of Captan, 2,3,7,8-Tetrachlorodibenzodioxin, Pentachlorophenol and Carbosulfan in Water: An Electrochemical Approach
Newman_2016_Psychopharmacology.(Berl)_233_925 Attenuation in rats of impairments of memory by scopolamine, a muscarinic receptor antagonist, by mecamylamine, a nicotinic receptor antagonist
Noremberg_2016_Biol.Trace.Elem.Res_169_77 Silicon Reverses Lipid Peroxidation but not Acetylcholinesterase Activity Induced by Long-Term Exposure to Low Aluminum Levels in Rat Brain Regions
Olsen_2016_Org.Biomol.Chem_14_1629 Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs
Ouyang_2016_Poult.Sci_95_99 Effects of abhydrolase domain containing 5 gene (ABHD5) expression and variations on chicken fat metabolism
Ouyang_2016_Anal.Chem_88_2353 Rapid Screening of Acetylcholinesterase Inhibitors by Effect-Directed Analysis Using LC x LC Fractionation, a High Throughput in Vitro Assay, and Parallel Identification by Time of Flight Mass Spectrometry
Paiva_2016_Genomics_107_40 Identification of a major Quantitative Trait Locus determining resistance to the organophosphate temephos in the dengue vector mosquito Aedes aegypti
Pakravan_2016_Hum.Exp.Toxicol_35_297 Measurement of cholinesterase enzyme activity before and after exposure to organophosphate pesticides in farmers of a suburb region of Mazandaran, a northern province of Iran
Pan_2016_Wiley.Interdiscip.Rev.Nanomed.Nanobiotechnol_8_85 Contact-facilitated drug delivery with Sn2 lipase labile prodrugs optimize targeted lipid nanoparticle drug delivery
Passlick_2016_Cereb.Cortex_26_51 The NG2 Protein Is Not Required for Glutamatergic Neuron-NG2 Cell Synaptic Signaling
Patricio-Martinez_2016_Neurosci_315_18 The recombinant C-terminal fragment of tetanus toxin protects against cholinotoxicity by intraseptal injection of beta-amyloid peptide (25-35) in rats
Pauziene_2016_J.Anat_228_26 Innervation of the rabbit cardiac ventricles
Payolla_2016_Mol.Cell.Endocrinol_422_192 High-fat diet during pregnancy and lactation impairs the cholinergic anti-inflammatory pathway in the liver and white adipose tissue of mouse offspring
Peng_2016_Chem.Biol.Interact_243_82 Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma
Phillips_2016_Environ.Health.Perspect_124_53 A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways
Rao_2016_Neurotoxicol_52_230 Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism
Renick_2016_Aquat.Toxicol_170_335 Effects of a pesticide and a parasite on neurological, endocrine, and behavioral responses of an estuarine fish
Rios_2016_Exp.Brain.Res_234_605 Dopamine-dependent modulation of rat globus pallidus excitation by nicotine acetylcholine receptors
Salaga_2016_J.Pharmacol.Exp.Ther_356_157 Encenicline, an alpha7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice
Sanchez-Santed_2016_Cortex_74_417 Organophosphate pesticide exposure and neurodegeneration
Santos_2016_Environ.Sci.Pollut.Res.Int_23_266 Brain cholinesterase reactivation as a marker of exposure to anticholinesterase pesticides: a case study in a population of yellow-legged gull Larus michahellis (Naumann, 1840) along the northern coast of Portugal
Sayin_2016_Auton.Neurosci_194_26 Assessment of cardiac autonomic tone in conscious rats
Schama_2016_Insect.Biochem.Mol.Biol_69_91 Rhodnius prolixus supergene families of enzymes potentially associated with insecticide resistance
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Selim_2016_Prep.Biochem.Biotechnol_46_131 High expression level of antioxidants and pharmaceutical bioactivities of endophytic fungus Chaetomium globosum JN711454
Shah_2016_Mov.Disord_31_111 Striatal and Cortical beta-Amyloidopathy and Cognition in Parkinson's Disease
Shaikh_2016_Biotechnol.Appl.Biochem_63_145 Forxiga (dapagliflozin): Plausible role in the treatment of diabetes-associated neurological disorders
Singh_2016_Curr.Neurovasc.Res_13_10 Reversal in Cognition Impairments, Cholinergic Dysfunction, and Cerebral Oxidative Stress Through the Modulation of Ryanodine Receptors (RyRs) and Cysteinyl Leukotriene-1 (CysLT1) Receptors
Small_2016_Neurosci.Lett_616_80 Ventral tegmental area muscarinic receptors modulate depression and anxiety-related behaviors in rats
Spicakova_2016_Food.Chem.Toxicol_88_100 Evaluation of possible inhibition of human liver drug metabolizing cytochromes P450 by two new acetylcholinesterase oxime-type reactivators
Stanton_2016_Pract.Neurol_16_42 Apathy: a practical guide for neurologists
Sternberg_2016_Autoimmun.Rev_15_113 Promoting sympathovagal balance in multiple sclerosis\; pharmacological, non-pharmacological, and surgical strategies
Story_2016_Environ.Toxicol.Chem_35_152 Fenitrothion, an organophosphorous insecticide, impairs locomotory function and alters body temperatures in Sminthopsis macroura (Gould 1845) without reducing metabolic rates during running endurance and thermogenic performance tests
Sun_2016_Bioorg.Med.Chem.Lett_26_747 Design and discovery of Novel Thiazole acetamide derivatives as anticholinesterase agent for possible role in the management of Alzheimer's
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Tamasaki_2016_Brain.Dev_38_113 Effects of donepezil and serotonin reuptake inhibitor on acute regression during adolescence in Down syndrome
Terwege_2016_ChemMedChem_11_429 omega-Imidazolyl- and omega-Tetrazolylalkylcarbamates as Inhibitors of Fatty Acid Amide Hydrolase: Biological Activity and in vitro Metabolic Stability
Tomaz_2016_Exp.Biol.Med.(Maywood)_241_40 Light therapy modulates serotonin levels and blood flow in women with headache. A preliminary study
Tonin_2016_Comp.Immunol.Microbiol.Infect.Dis_44_61 Novel markers of inflammatory response and hepatic dysfunction in canine leishmaniasis
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Tsoi_2016_J.Am.Med.Dir.Assoc_17_24 Time to Treatment Initiation in People With Alzheimer Disease: A Meta-Analysis of Randomized Controlled Trials
Tyukhtenko_2016_J.Biol.Chem_291_2556 Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES
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Ulbrich_2016_Biochem.J_473_423 Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system
Valenzuela-Munoz_2016_Mar.Genomics_25_103 Transcriptome mining: Multigene panel to test delousing drug response in the sea louse Caligus rogercresseyi
Vaquero_2016_Appl.Microbiol.Biotechnol_100_2047 Properties, structure, and applications of microbial sterol esterases
Vernekar_2016_Angew.Chem.Int.Ed.Engl_55_1412 Vacancy-Engineered Nanoceria: Enzyme Mimetic Hotspots for the Degradation of Nerve Agents
Vijayaraghavan_2016_J.Alzheimers.Dis_50_567 Association of Butyrylcholinesterase-K Allele and Apolipoprotein E varepsilon4 Allele with Cognitive Decline in Dementia with Lewy Bodies and Alzheimer's Disease
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Vrancheva_2016_Z.Naturforsch.C_71_9 Alkaloid profiles and acetylcholinesterase inhibitory activities of Fumaria species from Bulgaria
Wang_2016_Chem.Commun.(Camb)_52_3183 A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples
Wang_2016_Toxicol.Sci_149_145 Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury
Wang_2016_Arch.Toxicol_90_81 Fumonisins: oxidative stress-mediated toxicity and metabolism in vivo and in vitro
Winter_2016_Toxicol.Lett_244_136 Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase
Yamano_2016_J.Crit.Care_31_36 Low total cholesterol and high total bilirubin are associated with prognosis in patients with prolonged sepsis
Yuan_2016_Environ.Pollut_208_670 Targeting neurotrophic factors and their receptors, but not cholinesterase or neurotransmitter, in the neurotoxicity of TDCPP in Chinese rare minnow adults (Gobiocypris rarus)
Zhang_2016_Psychopharmacology.(Berl)_233_599 A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Abeta25-35-impaired mouse cognitive function
Barka_2016_Biochim.Biophys.Acta_1861_239 Identification of a triacylglycerol lipase in the diatom Phaeodactylum tricornutum
Caussy_2016_Atherosclerosis_246_280 Multiple microRNA regulation of lipoprotein lipase gene abolished by 3'UTR polymorphisms in a triglyceride-lowering haplotype harboring p.Ser474Ter
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Li_2016_Chin.Med.J.(Engl)_129_405 Chromosomal and Genetic Analysis of a Human Lung Adenocarcinoma Cell Line OM
Liu_2016_J.Cell.Biol_212_449 Neuroligin 1 regulates spines and synaptic plasticity via LIMK1\/cofilin-mediated actin reorganization
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Chen_2016_Mol.Med.Rep_14_446 Molecular evaluation of herbal compounds as potent inhibitors of acetylcholinesterase for the treatment of Alzheimer's disease
Choi_2016_Mol.Cancer.Ther_15_1201 Human Neural Stem Cells Overexpressing a Carboxylesterase Inhibit Bladder Tumor Growth
Choi_2016_BMB.Rep_49_349 Identification of amino acids related to catalytic function of Sulfolobus solfataricus P1 carboxylesterase by site-directed mutagenesis and molecular modeling
Chou_2016_Biotechnol.Appl.Biochem_63_371 A novel recombinant chlorophyllase from cyanobacterium Cyanothece sp. ATCC 51142 for the production of bacteriochlorophyllide a
Clarelli_2016_J.Alzheimers.Dis_52_1203 CHRNA7 Gene and Response to Cholinesterase Inhibitors in an Italian Cohort of Alzheimer's Disease Patients
Composto_2016_Exp.Mol.Pathol_100_522 Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug
Damar_2016_Expert.Rev.Neurother_16_671 Huperzine A as a neuroprotective and antiepileptic drug: a review of preclinical research
Daulatzai_2016_Curr.Pharm.Des_22_2411 Pharmacotherpy and Alzheimer's Disease: The M-Drugs (Melatonin, Minocycline, Modafinil, and Memantine) Approach
de Castro_2016_Comb.Chem.High.Throughput.Screen_19_334 Molecular Docking, Metal Substitution and Hydrolysis Reaction of Chiral Substrates of Phosphotriesterase
de Souza_2016_Chem.Biol.Interact_254_11 Coumarins as cholinesterase inhibitors: A review
Dgachi_2016_ChemMedChem_11_1318 Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Abeta1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy
Dolles_2016_ChemMedChem_11_1270 Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2 R Ligands To Combat Neurodegenerative Disorders
Dorywalska_2016_Mol.Cancer.Ther_15_958 Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design
Eckart_2016_Neuroimage_137_61 Acetylcholine modulates human working memory and subsequent familiarity based recognition via alpha oscillations
Elistratova_2016_Analyst_141_4204 Sensing activity of cholinesterases through a luminescence response of the hexarhenium cluster complex [{Re6S8}(OH)6](4.)
Fisar_2016_Prog.Neuropsychopharmacol.Biol.Psychiatry_69_112 Drugs related to monoamine oxidase activity
Flematti_2016_Planta_243_1361 Stereospecificity in strigolactone biosynthesis and perception
Fu_2016_J.Pharm.Sci_105_989 Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases
Fuenzalida_2016_Curr.Pharm.Des_22_2004 Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases
Gawel_2016_J.Psychopharmacol_30_676 Acquisition and reinstatement of ethanol-induced conditioned place preference in rats: Effects of the cholinesterase inhibitors donepezil and rivastigmine
Gibbons_2016_Curr.Pharm.Des_22_2124 The Cholinergic System: An Emerging Drug Target for Schizophrenia
Go_2016_Nutr.Neurosci_19_247 Neuroprotective effects of fermented soybean products (Cheonggukjang) manufactured by mixed culture of Bacillus subtilis MC31 and Lactobacillus sakei 383 on trimethyltin-induced cognitive defects mice
Grasing_2016_Behav.Brain.Res_312_148 A threshold model for opposing actions of acetylcholine on reward behavior: Molecular mechanisms and implications for treatment of substance abuse disorders
Groselj_2016_Mol.Divers_20_667 Synthesis and preliminary biological evaluations of (+)-isocampholenic acid-derived amides
Guler_2016_Environ.Sci.Pollut.Res.Int_23_12343 Electrochemical detection of malathion pesticide using acetylcholinesterase biosensor based on glassy carbon electrode modified with conducting polymer film
Haider_2016_Brain.Res_1644_141 beta-glucan attenuated scopolamine induced cognitive impairment via hippocampal acetylcholinesterase inhibition in rats
Hamulakova_2016_J.Inorg.Biochem_161_52 Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules
Heier_2016_J.Biol.Chem_291_11865 Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
Hiramoto_2016_Photodermatol.Photoimmunol.Photomed_32_129 Long-term UVA eye irradiation causes decreased learning ability in mice
Holleran_2016_Neuropsychopharmacology_41_2062 Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive-Like Behavior During Forced Abstinence From Alcohol Drinking
Ikhlef_2016_FEBS.Lett_590_1614 Paraoxonase 1-treated oxLDL promotes cholesterol efflux from macrophages by stimulating the PPARgamma-LXRalpha-ABCA1 pathway
Imai_2016_J.Pharm.Sci_105_714 Expression of Carboxylesterase Isozymes and Their Role in the Behavior of a Fexofenadine Prodrug in Rat Skin
Jansson_2016_Anal.Chem_88_6195 Monitoring Enzymatic Reactions in Real Time Using Venturi Easy Ambient Sonic-Spray Ionization Mass Spectrometry
Jayant_2016_Brain.Res_1642_397 Protective effect of transient receptor potential vanilloid subtype 1 (TRPV1) modulator, against behavioral, biochemical and structural damage in experimental models of Alzheimer's disease
Justin_2016_Nutr.Neurosci_19_269 Tannoid principles of Emblica officinalis renovate cognitive deficits and attenuate amyloid pathologies against aluminum chloride induced rat model of Alzheimer's disease
Kalkman_2016_Cell.Mol.Life.Sci_73_2511 Modulatory effects of alpha7 nAChRs on the immune system and its relevance for CNS disorders
Kan_2016_Behav.Brain.Res_312_265 Behavioral deficits and cholinergic pathway abnormalities in male Sanfilippo B mice
Kang_2016_Biotechnol.Lett_38_1009 Discovery of novel feruloyl esterase activity of BioH in Escherichia coli BL21(DE3)
Kang_2016_ACS.Nano_10_5346 Optical Detection of Enzymatic Activity and Inhibitors on Non-Covalently Functionalized Fluorescent Graphene Oxide
Kaur_2016_Regul.Toxicol.Pharmacol_80_82 Low dose X-irradiation mitigates diazepam induced depression in rat brain
Khan_2016_Med.Chem_12_238 Withanolides: Biologically Active Constituents in the Treatment of Alzheimer's Disease
Kim_2016_Behav.Brain.Res_312_39 Anti-amnesic effect of Dendropanax morbifera via JNK signaling pathway on cognitive dysfunction in high-fat diet-induced diabetic mice
Kim_2016_Pain_157_1314 Neuroligin 2 regulates spinal GABAergic plasticity in hyperalgesic priming, a model of the transition from acute to chronic pain
Kim_2016_J.Ethnopharmacol_188_123 Neuroprotective effects of Danggui-Jakyak-San on rat stroke model through antioxidant\/antiapoptotic pathway
Kuhl_2016_Cancer.Lett_378_51 Tissue-infiltrating plasma cells are an important source of carboxylesterase 2 contributing to the therapeutic efficacy of prodrugs
Kumar_2016_Bioresour.Technol_213_64 Modulation of fatty acid metabolism and tricarboxylic acid cycle to enhance the lipstatin production through medium engineering in Streptomyces toxytricini
Kuranobu_2016_Hepatol.Res_46_477 Cholesterol ester storage disease with a novel LIPA mutation (L264P) that presented massive hepatomegaly: A case report
Lau_2016_Brain.Res_1642_114 Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis
Lauretani_2016_Aging.Clin.Exp.Res_28_551 Parkinson's disease (PD) with dementia and falls is improved by AChEI? A preliminary study report
Le Guernic_2016_Ecotoxicology_25_1234 In situ effects of metal contamination from former uranium mining sites on the health of the three-spined stickleback (Gasterosteus aculeatus, L.)
Leitemperger_2016_Fish.Physiol.Biochem_42_1005 Early biochemical biomarkers for zinc in silver catfish (Rhamdia quelen) after acute exposure
Li_2016_Environ.Sci.Pollut.Res.Int_23_8275 Effects of 4-methylbenzylidene camphor (4-MBC) on neuronal and muscular development in zebrafish (Danio rerio) embryos
Li_2016_Hepatology_63_1860 Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice
Liu_2016_Mol.Genet.Genomics_291_1105 Genome-wide identification, classification and expression analysis in fungal-plant interactions of cutinase gene family and functional analysis of a putative ClCUT7 in Curvularia lunata
Lopez-Obando_2016_Planta_243_1441 Structural modelling and transcriptional responses highlight a clade of PpKAI2-LIKE genes as candidate receptors for strigolactones in Physcomitrella patens
Lutz_2016_Curr.Opin.Lipidol_27_257 Glucagon-like peptide-1, glucagon-like peptide-2, and lipid metabolism
Maester_2016_Appl.Microbiol.Biotechnol_100_5815 Characterization of EST3: a metagenome-derived esterase with suitable properties for biotechnological applications
Manabe_2016_Psychogeriatrics_16_202 Increased dosage of donepezil for the management of behavioural and psychological symptoms of dementia in dementia with Lewy bodies
Maqbool_2016_Bioorg.Med.Chem_24_2777 Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents
Molven_2016_Gastroenterology_150_1515 Lipase Genetic Variants in Chronic Pancreatitis: When the End Is Wrong, All's Not Well
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Musilek_2016_Med.Chem_12_362 Monooxime Bispyridinium Reactivators Bearing Xylene Linker Synthesis and In Vitro Evaluation on Model of Organophosphate-Inhibited Acetylcholinesterase
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Nishtala_2016_J.Neurochem_137_528 Direct interaction of the resistance to inhibitors of cholinesterase type 3 protein with the serotonin receptor type 3A intracellular domain
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Park_2016_J.Agric.Food.Chem_64_3353 Antiamnesic Effect of Broccoli (Brassica oleracea var. italica) Leaves on Amyloid Beta (Abeta)1-42-Induced Learning and Memory Impairment
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Wang_2016_J.Mol.Biol_428_2769 Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition
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Guerreno_2016_Aquat.Toxicol_177_365 Comparative study of toxicity and biochemical responses induced by sublethal levels of the pesticide azinphosmethyl in two fish species from North-Patagonia, Argentina
Khan_2016_J.Biomol.Struct.Dyn__1 Structure prediction and functional analyses of a thermostable lipase obtained from Shewanella putrefaciens
Kim_2016_Biol.Pharm.Bull_39_1130 Cinnamomum loureirii Extract Inhibits Acetylcholinesterase Activity and Ameliorates Trimethyltin-Induced Cognitive Dysfunction in Mice
Koh_2016_Lab.Anim.Res_32_105 Beneficial effect of diosgenin as a stimulator of NGF on the brain with neuronal damage induced by Abeta-42 accumulation and neurotoxicant injection
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Li_2016_Anal.Sci_32_719 Detection of Organophosphorus Pesticides with Colorimetry and Computer Image Analysis
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Matsumoto_2016_Front.Neurosci_10_226 Edrophonium Challenge Test for Blepharospasm
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Vazzana_2016_Comp.Biochem.Physiol.A.Mol.Integr.Physiol_201_61 Are mussels able to distinguish underwater sounds? Assessment of the reactions of Mytilus galloprovincialis after exposure to lab-generated acoustic signals
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Pastryk_2016_Chem.Biol.Interact_259_407 Effects of antiretroviral treatment on paraoxonase 1 (PON1) activity in rats
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Bellinato_2016_Biomed.Res.Int_2016_8603263 Resistance Status to the Insecticides Temephos, Deltamethrin, and Diflubenzuron in Brazilian Aedes aegypti Populations
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Ghisi_2016_Chemosphere_161_69 Integrated biomarker response in catfish Hypostomus ancistroides by multivariate analysis in the Pirapo River, southern Brazil
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Arikawa_2016_Eur.J.Pharmacol_789_17 Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation
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Chiantore_2016_J.Cancer.Res.Clin.Oncol_142_1751 Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs: additional evidence in HPV-induced tumorigenesis
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de Haro Jorge_2016_Pediatr.Surg.Int_32_723 Effectiveness of calretinin and role of age in the diagnosis of Hirschsprung disease
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Ramsay_2016_Front.Neurosci_10_375 Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration
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Zappaterra_2016_Meat.Sci_121_27 A gene and protein expression study on four porcine genes related to intramuscular fat deposition
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Chen_2016_Med.Sci.Monit_22_3196 Association Between Paraoxonase 2 Ser311Cys Polymorphism and Coronary Heart Disease Risk: A Meta-Analysis
Connor_2016_Neuron_91_1052 Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2
Doherty_2016_Physiol.Biochem.Zool_89_364 Exploring the Bone Proteome to Help Explain Altered Bone Remodeling and Preservation of Bone Architecture and Strength in Hibernating Marmots
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Emad_2016_Pharmacol.Rep_69_300 Attenuation of stress induced memory deficits by nonsteroidal anti-inflammatory drugs (NSAIDs) in rats: Role of antioxidant enzymes
Nguyen_2016_Mycobiology_44_291 Evaluation of Antioxidant, Anti-cholinesterase, and Anti-inflammatory Effects of Culinary Mushroom Pleurotus pulmonarius
Ntalli_2016_J.Nematol_48_248 Acetic Acid, 2-Undecanone, and (E)-2-Decenal Ultrastructural Malformations on Meloidogyne incognita
Voorhees_2016_Front.Neurosci_10_590 Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds
Carelli-Alinovi_2016_Clin.Hemorheol.Microcirc_64_679 Vascular dysfunction-associated with Alzheimer's disease
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Esteves_2016_Clin.Hemorheol.Microcirc_64_989 Erythrocyte nitric oxide in glaucoma patients - ex vivo study
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Mongalo_2016_J.Ethnopharmacol_194_789 Ethnobotany, phytochemistry, toxicology and pharmacological properties of Terminalia sericea Burch. ex DC. (Combretaceae) - A review
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Yu_2016_Fitoterapia_117_41 Four new steroids from the endophytic fungus Chaetomium sp. M453 derived of Chinese herbal medicine Huperzia serrata
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Gu_2016_Cell.Mol.Biol.(Noisy-le-grand)_62_44 The association between paraoxonase 1 gene polymorphisms and polycystic ovarian syndrome
Patil_2016_J.Clin.Diagn.Res_10_UC18 Contributing Factors for Morbidity and Mortality in Patients with Organophosphate Poisoning on Mechanical Ventilation: A Retrospective Study in a Teaching Hospital
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Haddi_2016_PLoS.One_11_e0156616 Sexual Success after Stress? Imidacloprid-Induced Hormesis in Males of the Neotropical Stink Bug Euschistus heros
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Krauskova_2016_Int.J.Pharm_509_41 Suppression of protein inactivation during freezing by minimizing pH changes using ionic cryoprotectants
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Mesman_2016_Front.Mol.Neurosci_9_166 Mest\/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset
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Campisi_2016_Sci.Rep_6_29799 Serotype IV Streptococcus agalactiae ST-452 has arisen from large genomic recombination events between CC23 and the hypervirulent CC17 lineages
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Kelberman_2016_Curr.Pharmacol.Rep_2_253 New Pharmacological Approaches to Treating Non-Motor Symptoms of Parkinson's Disease
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Papanicolaou_2016_Genome.Biol_17_192 The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species
Prekovic_2016_Sci.Rep_6_20369 Multidisciplinary investigation links backward-speech trait and working memory through genetic mutation
Cada_2016_Hosp.Pharm_51_405 Mepolizumab
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Himes_2016_Pediatrics_138_ Lysosomal Acid Lipase Deficiency Unmasked in Two Children With Nonalcoholic Fatty Liver Disease
Morrow_2016_Manag.Care_25_42 Three Breakthroughs Usher In New Era of Cholesterol Control
Paton_2016_Drugs.Today.(Barc)_52_287 Sebelipase alfa: enzymatic replacement treatment for lysosomal acid lipase deficiency
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Iram_2016_J.Neurosci_36_5185 Megf10 Is a Receptor for C1Q That Mediates Clearance of Apoptotic Cells by Astrocytes
Iram_2016_Neurobiol.Dis_96_84 Astrocytes from old Alzheimer's disease mice are impaired in Abeta uptake and in neuroprotection
Rosen_2016_Toxins.(Basel)_8_ Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins
Sandler_2016_Neuron_90_1028 A Novel Form of Local Plasticity in Tuft Dendrites of Neocortical Somatosensory Layer 5 Pyramidal Neurons
Simonovitch_2016_J.Alzheimers.Dis_51_915 Impaired Autophagy in APOE4 Astrocytes
Tervo_2016_Neuron_92_372 A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons
Panche_2016_J.Nutr.Sci_5_e47 Flavonoids: an overview
Clark_2016_Bioconjug.Chem_27_2839 Light-Up Channel Dyes for Haloalkane-Based Protein Labeling in Vitro and in Bacterial Cells
Kumar_2016_Interdiscip.Toxicol_9_101 Protection studies of new bis quaternary 2-(hydroxyimino)-N-(pyridin-3yl) acetamide derivatives (HNK-series) oximes against acute poisoning by dichlorvos (DDVP) in Swiss albino mice
Chidambaram_2016_Environ.Toxicol_31_1955 Sesame indicum, a nutritional supplement, elicits antiamnesic effect via cholinergic pathway in scopolamine intoxicated mice
Shen_2016_Neuroimmunomodulation_23_318 Effect of Melatonin and Resveratrol against Memory Impairment and Hippocampal Damage in a Rat Model of Vascular Dementia
Syed_2016_Environ.Toxicol_31_1761 Neurodevelopmental consequences of gestational and lactational exposure to pyrethroids in rats
Zarei_2016_Environ.Toxicol_31_1510 Study of the chlorpyrifos neurotoxicity using neural differentiation of adipose tissue-derived stem cells
Lord_2016_Cell.Rep_16_939 Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation
Hall_2016_J.Pharm.Sci_105_1633 Polysorbates 20 and 80 Degradation by Group XV Lysosomal Phospholipase A2 Isomer X1 in Monoclonal Antibody Formulations
Perez-Lloret_2016_NPJ.Parkinsons.Dis_2_16001 Deficits in cholinergic neurotransmission and their clinical correlates in Parkinson's disease
Elegheert_2016_Science_353_295 Structural basis for integration of GluD receptors within synaptic organizer complexes
Jaako_2016_J.Cell.Sci_129_3792 Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro
Yamanoi_2016_Oncotarget_7_47620 Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer
Ren_2016_Neurosci.Lett_619_73 Meta-analyses of four polymorphisms of lipoprotein lipase associated with the risk of Alzheimer's disease
Tani_2016_Atherosclerosis_253_7 High-density lipoprotein subpopulation profiles in lipoprotein lipase and hepatic lipase deficiency
Pingitore_2016_J.Clin.Lipidol_10_816 Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia
Liu_2016_J.Clin.Lipidol_10_199 A Chinese patient with recurrent pancreatitis during pregnancy induced by hypertriglyceridemia associated with compound heterozygosity (Glu242Lys and Leu252VaL) in the lipoprotein lipase gene
Geraets_2016_Orphanet.J.Rare.Dis_11_40 Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis
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Metelitsina_2016_Retin.Cases.Brief.Rep_10_211 BATTEN DISEASE CAUSED BY A NOVEL MUTATION IN THE PPT1 GENE
Niida_2016_Brain.Dev_38_674 A girl with infantile neuronal ceroid lipofuscinosis caused by novel PPT1 mutation and paternal uniparental isodisomy of chromosome 1
Sleat_2016_Gene_593_284 Analysis of large-scale whole exome sequencing data to determine the prevalence of genetically-distinct forms of neuronal ceroid lipofuscinosis
Akiko_2016_CEN.Case.Rep_5_192 A case of acquired lecithin:cholesterol acyltransferase deficiency with sarcoidosis that remitted spontaneously
Gomez-Moyano_2016_J.Eur.Acad.Dermatol.Venereol_30_157 Chanarin-Dorfman syndrome in three siblings in a non-consanguineous family
Gopalakrishnan_2016_J.Assoc.Physicians.India_64_90 Familial Lecithin Cholesterol Acyl Transferase Deficiency with Chronic Kidney Disease
Gupta_2016_Gene_575_359 Chanarin Dorfman syndrome: a case report with novel nonsense mutation
Ingle_2016_Indian.J.Nephrol_26_313 Secret in the eyes - fish eye disease
Lucca_2016_G.Ital.Nefrol_33_ [Lecithin:Cholesterol Acyltransferase Deficiency, from genes to therapy]
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Shamburek_2016_Circ.Res_118_73 Safety and Tolerability of ACP-501, a Recombinant Human Lecithin:Cholesterol Acyltransferase, in a Phase 1 Single-Dose Escalation Study
Takeichi_2016_J.Dermatol.Sci_81_134 Bi-allelic nonsense mutations inABHD5 underlie a mild phenotype of Dorfman-Chanarin syndrome
Waheed_2016_J.Coll.Physicians.Surg.Pak_26_787 Chanarin-Dorfman Syndrome
Blommaert_2016_J.Child.Neurol_31_1220 Diagnosis and Management of Drooling in Children With Progressive Dystonia: A Case Series of Patients With MEGDEL Syndrome
Zeharia_2016_Eur.J.Hum.Genet_24_1778 Mitochondrial hepato-encephalopathy due to deficiency of QIL1\/MIC13 (C19orf70), a MICOS complex subunit
Gaudet_2016_Hum.Gene.Ther_27_916 Long-Term Retrospective Analysis of Gene Therapy with Alipogene Tiparvovec and Its Effect on Lipoprotein Lipase Deficiency-Induced Pancreatitis
Rodrigues_2016_J.Clin.Lipidol_10_394 Pathogenic classification of LPL gene variants reported to be associated with LPL deficiency
Peng_2016_Autophagy_12_2167 ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2
Pigg_2016_Acta.Derm.Venereol_96_932 Spectrum of Autosomal Recessive Congenital Ichthyosis in Scandinavia: Clinical Characteristics and Novel and Recurrent Mutations in 132 Patients
Li_2016_Eur.J.Hum.Genet_24_1274 Against all odds: blended phenotypes of three single-gene defects
Nicholas_2016_J.Clin.Endocrinol.Metab_101_4521 Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ
Hu_2016_Mol.Cell.Endocrinol_423_60 Thyroglobulin gene mutations in Chinese patients with congenital hypothyroidism
Lisi_2016_J.Endocrinol.Invest_39_1039 Intracellular retention of thyroglobulin in the absence of the low-density lipoprotein receptor-associated protein (RAP) is likely due to premature binding to megalin in the biosynthetic pathway
Mittal_2016_J.Hum.Genet_61_867 Mutations in the genes for thyroglobulin and thyroid peroxidase cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability
Kettwig_2016_BMC.Neurol_16_74 Compound heterozygous variants in PGAP1 causing severe psychomotor retardation, brain atrophy, recurrent apneas and delayed myelination: a case report and literature review
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Cai_2016_Lipids.Health.Dis_15_148 Endothelial lipase genetic polymorphisms and the lipid-lowering response in patients with coronary artery disease on rosuvastatin
Hernandez-Tobias_2016_Ethn.Dis_26_477 PPARG-LYPLAL1 Multi-Allelic Combination Associated with Obesity and Overweight in Mexican Adolescent Females
Khovidhunkit_2016_J.Clin.Lipidol_10_505 Rare and common variants in LPL and APOA5 in Thai subjects with severe hypertriglyceridemia: A resequencing approach
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Ripatti_2016_PLoS.Genet_12_e1006078 The Contribution of GWAS Loci in Familial Dyslipidemias
Wang_2016_Sci.Rep_6_20691 Effects of Obesity Related Genetic Variations on Visceral and Subcutaneous Fat Distribution in a Chinese Population
Zhang_2016_Methods.Mol.Biol_1481_29 Methods for Studying Wnt Protein Modifications\/Inactivations by Extracellular Enzymes, Tiki and Notum
Cahn_2016_Expert.Opin.Emerg.Drugs_21_409 An update on DPP-4 inhibitors in the management of type 2 diabetes
Wen_2016_J.Neurosci_36_10870 Fatigue in Rapsyn-Deficient Zebrafish Reflects Defective Transmitter Release
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Li_2016_Mol.Med.Rep_13_2476 Targeting of cancerassociated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment
Wong_2016_Peptides_75_80 Neuropeptide Y is a physiological substrate of fibroblast activation protein: Enzyme kinetics in blood plasma and expression of Y2R and Y5R in human liver cirrhosis and hepatocellular carcinoma
Gavilan_2016_Philos.Trans.R.Soc.Lond.B.Biol.Sci_371_20150039 Xenacoelomorpha: a case of independent nervous system centralization?
Arand_2016_Matters_1_ Microsomal epoxide hydrolase is not a 2-arachidonyl glycerol hydrolase
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Patil_2016_Interdiscip.Sci_8_284 Computational Analysis of the Domain Architecture and Substrate-Gating Mechanism of Prolyl Oligopeptidases from Shewanella woodyi and Identification of Probable Lead Molecules
Peng_2016_Placenta_46_92 DNA methylation-associated repression of MEST\/PEG1 expression contributes to the invasion of extravillous trophoblast cells
Heubi_2016_J.Pediatr_176_156 Safety and Efficacy of a Novel Microbial Lipase in Patients with Exocrine Pancreatic Insufficiency due to Cystic Fibrosis: A Randomized Controlled Clinical Trial
Lindsay_2016_Biopolymers_105_864 DMSO enhanced conformational switch of an interfacial enzyme
Adesioye_2016_Enzyme.Microb.Technol_93-94_79 Phylogeny, classification and metagenomic bioprospecting of microbial acetyl xylan esterases
Belforte_2016_Mol.Cell.Endocrinol_419_172 Compound heterozygous DUOX2 gene mutations (c.2335-1G>C\/c.3264_3267delCAGC) associated with congenital hypothyroidism. Characterization of complex cryptic splice sites by minigene analysis
Bezuidt_2016_Front.Microbiol_7_723 The Geobacillus Pan-Genome: Implications for the Evolution of the Genus
El-Sikhry_2016_PLoS.One_11_e0160380 Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria
Herbst_2016_Nature_531_533 Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases
Hirano_2016_Metabolism_65_893 Anagliptin, a dipeptidyl peptidase-4 inhibitor, decreases macrophage infiltration and suppresses atherosclerosis in aortic and coronary arteries in cholesterol-fed rabbits
Osonoi_2016_Peptides_86_118 Add-on therapy with anagliptin in Japanese patients with type-2 diabetes mellitus treated with metformin and miglitol can maintain higher concentrations of biologically active GLP-1\/total GIP and a lower concentration of leptin
Sato_2016_Diabetologia_59_2426 Anagliptin increases insulin-induced skeletal muscle glucose uptake via an NO-dependent mechanism in mice
Tahara_2016_Curr.Vasc.Pharmacol_14_552 Anagliptin, A Dipeptidyl Peptidase-4 Inhibitor Ameliorates Arterial Stiffness in Association with Reduction of Remnant-Like Particle Cholesterol and Alanine Transaminase Levels in Type 2 Diabetic Patients
Accardo_2016_J.Biomed.Nanotechnol_12_1076 Diolein Based Nanostructures as Targeted Theranostics
Kulshreshtha_2016_Neurol.Sci_37_1403 Current pharmacotherapy and putative disease-modifying therapy for Alzheimer's disease
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Mohan_2016_Bioresour.Technol_213_204 Microbial assisted High Impact Polystyrene (HIPS) degradation
Mokrushina_2016_Bull.Exp.Biol.Med_161_83 New Genetic Constructs for Generation of Stable Therapeutic Antibodies to Organophosphorus Toxins in Methylotrophic Yeasts Pichia Pastoris
Kim_2016_Anal.Chem_88_9259 Molecular Rotors for the Detection of Chemical Warfare Agent Simulants
Pereira_2016_Drug.Dev.Ind.Pharm_42_985 Factors influencing the erosion rate and the drug release kinetics from organogels designed as matrices for oral controlled release of a hydrophobic drug
Ramalho_2016_Curr.Med.Chem_23_1041 Computational Enzymology and Organophosphorus Degrading Enzymes: Promising Approaches Toward Remediation Technologies of Warfare Agents and Pesticides
Zhao_2016_Angew.Chem.Int.Ed.Engl_55_13224 Ultra-Fast Degradation of Chemical Warfare Agents Using MOF-Nanofiber Kebabs
Trubitsyna_2016_Eksp.Klin.Gastroenterol__35 THE CONCENTRATION OF ACETYLCHOLINE AND THE LEVEL CHOLINESTERASE ACTIVITY IN THE SERUM OF PATIENTS WITH GASTRIC ULCER, DUODENAL ULCER AND ALCOHOLIC CHRONIC PANCREATITIS
Schalk_2016_Environ.Microbiol_18_3227 An overview of the biological metal uptake pathways in Pseudomonas aeruginosa
Das_2016_J.Phys.Chem.B_120_11720 Molecular Mechanism behind Solvent Concentration-Dependent Optimal Activity of Thermomyces lanuginosus Lipase in a Biocompatible Ionic Liquid: Interfacial Activation through Arginine Switch
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Scalvini_2016_Sci.Rep_6_31046 Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL
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Park_2016_Chem.Sci_7_3703 A carboxylesterase-selective ratiometric fluorescent two-photon probe and its application to hepatocytes and liver tissues
Campbell_2016_Nat.Chem.Biol_12_944 The role of protein dynamics in the evolution of new enzyme function
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Droste_2016_Am.J.Disaster.Med_11_89 A systems dynamics approach to the efficacy of oxime therapy for mild exposure to sarin gas
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Lee_2016_Oncotarget_7_57442 Potential role of the N-MYC downstream-regulated gene family in reprogramming cancer metabolism under hypoxia
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Chroni_2016_Acta.Neurol.Belg_116_57 Low vitamin D levels in healthy controls and patients with autoimmune neuromuscular disorders in Greece
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Molin_2016_J.Clin.Neurophysiol_33_340 Compound Motor Action Potential: Electrophysiological Marker for Muscle Training
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Obruca_2016_Appl.Microbiol.Biotechnol_100_1365 Evaluation of 3-hydroxybutyrate as an enzyme-protective agent against heating and oxidative damage and its potential role in stress response of poly(3-hydroxybutyrate) accumulating cells
Askari_2016_Sao.Paulo.Med.J_134_121 Interaction of lipoprotein lipase polymorphisms with body mass index and birth weight to modulate lipid profiles in children and adolescents: the CASPIAN-III Study
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Eddleston_2016_Br.J.Clin.Pharmacol_81_462 Pharmacological treatment of organophosphorus insecticide poisoning: the old and the (possible) new
Flannery_2016_J.Neuroinflammation_13_267 Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication
Gong_2016_Anal.Chem_88_8309 Ultrasensitive Fluorescent Probes Reveal an Adverse Action of Dipeptide Peptidase IV and Fibroblast Activation Protein during Proliferation of Cancer Cells
Kelly_2016_Biochim.Biophys.Acta_1861_1253 Oil is on the agenda: Lipid turnover in higher plants
Rinaldi_2016_Genetics_204_1089 The Roles of beta-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana
Berezina_2016_N.Biotechnol_33_231 Improvement of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) production by dual feeding with levulinic acid and sodium propionate in Cupriavidus necator
Chen_2016_Front.Microbiol_7_1389 Orf Virus 002 Protein Targets Ovine Protein S100A4 and Inhibits NF-B Signaling
Culic_2016_Clin.Rheumatol_35_2565 Serum activities of adenosine deaminase, dipeptidyl peptidase IV and prolyl endopeptidase in patients with fibromyalgia: diagnostic implications
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Hayes_2016_J.Agric.Food.Chem_64_146 Transport of a Prolyl Endopeptidase Inhibitory Peptide across the Blood-Brain Barrier Demonstrated Using the hCMEC\/D3 Cell Line Transcytosis Assay
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Chabi_2016_Parasit.Vectors_9_182 Insecticide susceptibility of natural populations of Anopheles coluzzii and Anopheles gambiae (sensu stricto) from Okyereko irrigation site, Ghana, West Africa
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Woo_2016_J.Med.Food_19_486 Conjugated Linoleic Triacylglycerols Exhibit Superior Lymphatic Absorption Than Free Conjugate Linoleic Acids and Have Antiobesity Properties
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Aitken_2016_Andrology_4_345 Involvement of homocysteine, homocysteine thiolactone, and paraoxonase type 1 (PON-1) in the etiology of defective human sperm function
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