2022

Miranda-Miranda_2022_Genes.(Basel)_13_ A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in Fasciola hepatica Carboxylesterase B
Liu_2022_Front.Microbiol_13_819086 Cloning and Functional Characterization of the Polyketide Synthases Based on Genome Mining of Preussia isomera XL-1326
Erickson_2022_Nat.Commun_13_7850 Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity
Thia_2022_J.Evol.Biol__ The redlegged earth mite draft genome provides new insights into pesticide resistance evolution and demography in its invasive Australian range
Gudi_2022_Planta_255_115 Unravelling consensus genomic regions associated with quality traits in wheat using meta-analysis of quantitative trait loci
Behera_2022_Front.Plant.Sci_13_1056582 Acyl-CoA-dependent and acyl-CoA-independent avocado acyltransferases positively influence oleic acid content in nonseed triacylglycerols
Zhang_2022_Int.J.Mol.Sci_24_383 The Functional Characterization of Carboxylesterases Involved in the Degradation of Volatile Esters Produced in Strawberry Fruits
Martinez-Rivas_2022_Hortic.Res_9_uhac095 Strawberry fruit FanCXE1 carboxylesterase is involved in the catabolism of volatile esters during the ripening process
Wang_2022_Front.Plant.Sci_13_1019538 Comprehensive analysis of the carboxylesterase gene reveals that NtCXE22 regulates axillary bud growth through strigolactone metabolism in tobacco
Dou_2022_Catal.Sci.Technol_12_7448 Structural and mechanistic insights into enantioselectivity toward near-symmetric esters of a novel carboxylesterase RoCE
Ren_2022_Microbiol.Spectr__e0330822 Acquisition of T6SS Effector TseL Contributes to the Emerging of Novel Epidemic Strains of Pseudomonas aeruginosa
Ariaeenejad_2022_Sci.Total.Environ__161066 Efficiency of an alkaline, thermostable, detergent compatible and organic solvent tolerant lipase with hydrolytic potential in biotreatment of wastewater
Chen_2022_Plant.J__ New insights into the function of plant tannase with promiscuous acyltransferase activity
Yao_2022_Plant.J_111_117 Insights into acylation mechanisms: co-expression of serine carboxypeptidase-like acyltransferases and their non-catalytic companion paralogs
Lo Verde_2022_Food.Res.Int_162_111996 A highly active esterase from Lactobacillus helveticus hydrolyzes chlorogenic acid in sunflower meal to prevent chlorogenic acid induced greening in sunflower protein isolates
Liaw_2022_Microorganisms_10_2403 Molecular Cloning and Characterization of a New Family VI Esterase from an Activated Sludge Metagenome
Kim_2022_Pestic.Biochem.Physiol_188_105277 Molecular and kinetic properties of three acetylcholinesterases in the Varroa mite, Varroa destructor
Wang_2022_Commun.Biol_5_1249 The protein conformational basis of isoflavone biosynthesis
Aher_2022_Front.Plant.Sci_13_962667 Loss-of-function of triacylglycerol lipases are associated with low flour rancidity in pearl millet [Pennisetum glaucum (L.) R. Br.]
Nakagame_2022_Appl.Biochem.Biotechnol__ Purification and Characterization of Class III Lipase from a White-Rot Fungus Pleurotus ostreatus
Zou_2022_Microbiol.Res_266_127222 Analysis of virulence proteins in pathogenic Acinetobacter baumannii to provide early warning of zoonotic risk
Ma_2022_J.Hazard.Mater_443_130197 Characterization of a new chlorimuron-ethyl-degrading strain Cedecea sp. LAM2020 and biodegradation pathway revealed by multiomics analysis
Thomas_2022_Protein.Sci__e4470 Bioplastic degradation by a polyhydroxybutyrate depolymerase from a thermophilic soil bacterium
Johan_2022_Int.J.Biol.Macromol__ A new hyper-thermostable carboxylesterase from Anoxybacillus geothermalis D9
Hwang_2022_Biochem.Biophys.Res.Commun_629_159 Structural basis for the substrate specificity of an S-formylglutathione hydrolase derived from Variovorax sp. PAMC 28711
Eiamthong_2022_Angew.Chem.Int.Ed.Engl_15_e202203061 Discovery and Genetic Code Expansion of a Polyethylene Terephthalate (PET) Hydrolase from the Human Saliva Metagenome for the Degradation and Bio-Functionalization of PET
Esakkiraj_2022_Int.J.Biol.Macromol__ Functional and molecular characterization of a cold-active lipase from Psychrobacter celer PU3 with potential antibiofilm property
Meyer-Cifuentes_2022_Front.Bioeng.Biotechnol_10_930140 Molecular and Biochemical Differences of the Tandem and Cold-Adapted PET Hydrolases Ple628 and Ple629, Isolated From a Marine Microbial Consortium
Li_2022_Biochem.Biophys.Res.Commun_626_100 Structural insight and engineering of a plastic degrading hydrolase Ple629
Rauter_2022_Microorganisms_10_1316 Cutinase ACut2 from Blastobotrysraffinosifermentans for the Selective Desymmetrization of the Symmetric Diester Diethyl Adipate to the Monoester Monoethyl Adipate
Cui_2022_Microbiol.Spectr__e0102722 The Cell-Cell Communication Signal Indole Controls the Physiology and Interspecies Communication of Acinetobacter baumannii
Zhang_2023_Bioprocess.Biosyst.Eng_46_171 Enantioselective resolution of (R,S)-DMPM to prepare (R)-DMPM by an adsorbed-covalent crosslinked esterase PAE07 from Pseudochrobactrum asaccharolyticum WZZ003
Saha_2022_Arch.Microbiol_204_498 Cloning, expression and characterization of PURase gene from Pseudomonas sp. AKS31
Yu_2022_Plant.Physiol.Biochem_186_88 Lignin biosynthesis regulated by CsCSE1 is required for Cucumis sativus defence to Podosphaera xanthi
Ristinmaa_2022_J.Biol.Chem_298_101758 Structural diversity and substrate preferences of three tannase enzymes encoded by the anaerobic bacterium Clostridium butyricum
Hwang_2022_Crystals_12_546 Identification, Characterization, and Preliminary X-ray Diffraction Analysis of a Novel Esterase (ScEst) from Staphylococcus chromogenes
Do_2022_Crystals_12_46 Sequence Analysis and Preliminary X-ray Crystallographic Analysis of an Acetylesterase (LgEstI) from Lactococcus garvieae
Matabaro_2022_bioRxiv__ Molecular insight into the enzymatic macrocyclization of multiply backbone N-methylated peptides
Li_2022_Fish.Shellfish.Immunol_S1050-4648_00352 Characterization of 4 deletion mutants of Pseudomonas plecoglossicida and their potential for live attenuated vaccines in large yellow croaker (Larimichthys crocea)
Liu_2022_Dev.Comp.Immunol_132_104410 The juvenile hormone epoxide hydrolase homolog in Penaeus vannamei plays immune-related functions
Pineda-Mendoza_2022_Front.Microbiol_13_911269 Rahnella sp., a Dominant Symbiont of the Core Gut Bacteriome of Dendroctonus Species, Has Metabolic Capacity to Degrade Xylan by Bifunctional Xylanase-Ferulic Acid Esterase
Lu_2022_Front.Microbiol_13_851969 Metagenomic Screening for Lipolytic Genes Reveals an Ecology-Clustered Distribution Pattern
Liu_2022_Front.Microbiol_13_855658 Characterization of a Novel Esterase Est33 From an Antarctic Bacterium: A Representative of a New Esterase Family
Vidal_2022_Front.Microbiol_13_868839 Metagenomic Mining for Esterases in the Microbial Community of Los Rueldos Acid Mine Drainage Formation
Ahmed_2022_Mar.Drugs_20_ Evaluation of a Thermophilic, Psychrostable, and Heavy Metal-Resistant Red Sea Brine Pool Esterase
Huang_2022_Acta.Crystallogr.D.Struct.Biol_78_735 The structure and molecular dynamics of prolyl oligopeptidase from Microbulbifer arenaceous provide insights into catalytic and regulatory mechanisms
Britton_2022_BMC.Res.Notes_15_183 Contribution of a novel gene to lysergic acid amide synthesis in Metarhizium brunneum
Liu_2022_Front.Bioeng.Biotechnol_10_865787 Catalytic Features and Thermal Adaptation Mechanisms of a Deep Sea Bacterial Cutinase-Type Poly(Ethylene Terephthalate) Hydrolase
Mohanan_2022_Front.Bioeng.Biotechnol_10_854298 Characterization of Polymer Degrading Lipases, LIP1 and LIP2 From Pseudomonas chlororaphis PA23
Carr_2022_Front.Microbiol_13_888343 Identification of BgP, a Cutinase-Like Polyesterase From a Deep-Sea Sponge-Derived Actinobacterium
Hemmerling_2022_Angew.Chem.Int.Ed.Engl__e202116614 Modular Halogenation, alpha-Hydroxylation, and Acylation by a Remarkably Versatile Polyketide Synthase
Fraley_2022_Angew.Chem.Int.Ed.Engl_61_e202206385 Structure of a promiscuous thioesterase domain responsible for branching acylation in polyketide biosynthesis
Won_2022_Protein.Expr.Purif__106077 Functional production, characterization, and immobilization of a cold-adapted cutinase from Antarctic Rhodococcus sp
Won_2022_J.Microbiol.Biotechnol_33_1 Synthesis of Short-Chain Alkyl Butyrate through Esterification Reaction Using Immobilized Rhodococcus Cutinase and Analysis of Substrate Specificity through Molecular Docking
Kasmaei_2022_Front.Microbiol_13_1050160 Crystal structure of the feruloyl esterase from Lentilactobacillus buchneri reveals a novel homodimeric state
Yang_2022_Biochem.Biophys.Res.Commun_600_117 Structure-guided rational design of the Geobacillus thermoglucosidasius feruloyl esterase GthFAE to improve its thermostability
Guercio_2022_Commun.Biol_5_126 Structural and functional analyses explain Pea KAI2 receptor diversity and reveal stereoselective catalysis during signal perception
Ma_2022_Enzyme.Microb.Technol_156_109989 Ancestral sequence reconstruction and spatial structure analysis guided alteration of longer-chain substrate catalysis for Thermomicrobium roseum lipase
van der Ent_2022_Biochemistry__ Structure and Mechanism of a Cold-Adapted Bacterial Lipase
Kawai_2022_Chembiochem__ The alpha\/beta hydrolase AzpM catalyzes dipeptide synthesis in alazopeptin biosynthesis using two molecules of carrier protein-tethered amino acid
Khara_2022_Biologia.(Bratisl)__ A novel acidic and SDS tolerant halophilic lipase from moderate halophile Nesterenkonia sp. strain F: molecular cloning, structure analysis and biochemical characterization
Baek_2022_Environ.Pollut_299_118890 Elucidating the biodegradation pathway and catabolic genes of benzophenone-3 in Rhodococcus sp. S2-17
Fu_2022_3.Biotech_12_24 Biochemical characterization of a novel feruloyl esterase from Burkholderia pyrrocinia B1213 and its application for hydrolyzing wheat bran
Zhou_2022_ACS.Catal_12_762 Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain
Weigert_2022_Protein.Sci__e4500 Investigation of the halophilic PET hydrolase PET6 from Vibrio gazogenes
Shang_2022_Sci.Total.Environ_806_151357 Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp. YS-1 and characterization of two initial degrading esterases
Sonnendecker_2022_ChemSusChem_15_e202101062 Low Carbon Footprint Recycling of Post-Consumer PET Plastic with a Metagenomic Polyester Hydrolase
Frank_2022_ACS.Catal_12_25 Real-Time Noninvasive Analysis of Biocatalytic PET Degradation
Pfaff_2022_ACS.Catalysis_12_9790 Multiple Substrate Binding Mode-Guided Engineering of a Thermophilic PET Hydrolase
Sagong_2022_J.Hazard.Mater_429_128267 Structural and functional characterization of an auxiliary domain-containing PET hydrolase from Burkholderiales bacterium
Tan_2022_World.J.Microbiol.Biotechnol_38_60 Extracellular secretion of a cutinase with polyester-degrading potential by E. coli using a novel signal peptide from Amycolatopsis mediterranei
Li_2022_J.Agric.Food.Chem_70_5794 Overexpression of PxalphaE14 Contributing to Detoxification of Multiple Insecticides in Plutella xylostella (L.)
Kim_2022_Front.Microbiol_13_1005415 Polyurethane biodegradation by Serratia sp. HY-72 isolated from the intestine of the Asian mantis Hierodula patellifera
Lin_2022_J.Agric.Food.Chem_70_13349 Enzymatic Cleavage of Diferuloyl Cross-Links in Corn Bran Arabinoxylan by Two Bacterial Feruloyl Esterases
Ding_2022_Front.Microbiol_12_798194 Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus
Schenkmayerova_2022_Biorxiv__ A catalytic mechanism for Renilla-type bioluminescence
Arellano-Saab_2022_J.Biol.Chem_298_101734 A novel strigolactone receptor antagonist provides insights into the structural inhibition, conditioning, and germination of the crop parasite Striga
Zarban_2022_Plant.Physiol_188_1369 Rational design of Striga hermonthica-specific seed germination inhibitors
Teng_2022_Pestic.Biochem.Physiol_184_105105 Associations between acetylcholinesterase-1 mutations and chlorpyrifos resistance in beet armyworm, Spodoptera exigua
Loll-Krippleber_2022_Microb.Cell.Fact_21_280 Development of a yeast whole-cell biocatalyst for MHET conversion into terephthalic acid and ethylene glycol
Tarazona_2022_Chem.Catal_2_3573 Rapid depolymerization of poly(ethylene terephthalate) thin films by a dual-enzyme system and its impact on material properties
Bell_2022_Nat.Catal_5_673 Directed evolution of an efficient and thermostable PET depolymerase
Joho_2022_Biochemistry__ Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity
Charupanit_2022_Molecules_27_ In Silico Identification of Potential Sites for a Plastic-Degrading Enzyme by a Reverse Screening through the Protein Sequence Space and Molecular Dynamics Simulations
Lu_2022_Nature_604_662 Machine learning-aided engineering of hydrolases for PET depolymerization
Chen_2022_Nat.Commun_13_7138 Biodegradation of highly crystallized poly(ethylene terephthalate) through cell surface codisplay of bacterial PETase and hydrophobin
Hwang_2022_Sci.Total.Environ__156890 Enhanced biodegradation of waste poly(ethylene terephthalate) using a reinforced plastic degrading enzyme complex
Brott_2022_Eng.Life.Sci_22_192 Engineering and evaluation of thermostable IsPETase variants for PET degradation
Gupta_2022_Biorxiv__ Machine Learning-Based Enzyme Engineering of PETase for Improved Efficiency in Degrading Non-Biodegradable Plastic
Schubert_2022_Chembiochem__e202200516 Reaction Pathways for the Enzymatic Degradation of Poly(Ethylene Terephthalate): What Characterizes an Efficient PET-Hydrolase?
Aer_2022_Environ.Res_212_113472 Overexpression and kinetic analysis of Ideonella sakaiensis PETase for polyethylene terephthalate (PET) degradation
Aboelnga_2022_ACS.Sustain.Chem.Eng_10_15857 QM\/MM Investigation to Identify the Hallmarks of Superior PET Biodegradation Activity of PETase over Cutinase
Erickson_2022_ChemSusChem_15_e202101932 Comparative performance of PETase as a function of reaction conditions, substrate properties, and product accumulation
Britikov_2022_Crystals_12_712 Elucidation of the Conformational Transition of Oligopeptidase B by an Integrative Approach Based on the Combination of X-ray, SAXS, and Essential Dynamics Sampling Simulation
Yang_2022_Appl.Biochem.Biotechnol__ Possible Charged Residue Switch for Acylglycerol Selectivity of Lipase MAS1
Zhao_2022_Int.J.Mol.Sci_23_5822 Structural Basis for the Regiospecificity of a Lipase from Streptomyces sp. W007
Lin_2022_Ecotoxicol.Environ.Saf_248_114301 Multiple acetylcholinesterases in Pardosa pseudoannulata brain worked collaboratively to provide protection from organophosphorus insecticides
Schnettler-Fernandez_2022_Biorxiv__ Ultrahigh-throughput directed evolution of a metal-free alpha\/beta-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase
Schnettler_2022_J.Am.Chem.Soc__ Ultrahigh-Throughput Directed Evolution of a Metal-Free alpha\/beta-Hydrolase with a Cys-His-Asp Triad into an Efficient Phosphotriesterase
Liu_2022_Protein.Expr.Purif__106165 Enhancing the secretion of a feruloyl esterase in Bacillus subtilis by signal peptide screening and rational design
Osamura_2022_J.Biosci.Bioeng_S1389-1723_00128 Efficient monoacylglycerol synthesis by carboxylesterase EstGtA2 from Geobacillus thermodenitrificans in a solvent-free two-phase system
Di Bisceglie_2022_Polymers.(Basel)_14_411 Cutinase-Catalyzed Polyester-Polyurethane Degradation: Elucidation of the Hydrolysis Mechanism
de Queiros Eugenio_2022_J.Biotechnol__ Novel efficient enzymatic synthesis of the key-reaction intermediate of PET depolymerization, mono(2-hydroxyethyl terephthalate) - MHET
Zhang_2022_J.Agric.Food.Chem__ Molecular and Biochemical Analyses of a Novel Trifunctional Endoxylanase\/Endoglucanase\/Feruloyl Esterase from the Human Colonic Bacterium Bacteroides intestinalis DSM 17393
Charlier_2022_Biophys.J__ An NMR look at an engineered PET depolymerase
Zeng_2022_ACS.Catal_12_3033 Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy
Oh_2022_Bioprocess.Biosyst.Eng__ Secretory production of an engineered cutinase in Bacillus subtilis for efficient biocatalytic depolymerization of polyethylene terephthalate
Arnling Baath_2022_JACS.Au_2_1223 Sabatier Principle for Rationalizing Enzymatic Hydrolysis of a Synthetic Polyester
Hsu_2022_Sci.Rep_12_1975 The ACE genes in Aphelenchoides besseyi isolates and their expression correlation to the fenamiphos treatment
Setlur_2022_Mol.Biotechnol__ Comprehensive Molecular Interaction Studies to Construe the Repellent\/Kill Activity of Geraniol During Binding Event Against Aedes aegypti Proteins
Ceneviva_2022_Bioengineering.(Basel)_9_228 Poly(3-mercapto-2-methylpropionate), a Novel alpha-Methylated Bio-Polythioester with Rubber-like Elasticity, and Its Copolymer with 3-hydroxybutyrate: Biosynthesis and Characterization
Binyang_2022_Parasit.Vectors_15_53 Distribution of acetylcholinesterase (Ace-1(R)) target-site G119S mutation and resistance to carbamates and organophosphates in Anopheles gambiae sensu lato populations from Cameroon
Heo_2022_Molecules_27_2317 Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain
Dongus_2022_Plant.J__ Cavity surface residues of PAD4 and SAG101 contribute to EDS1 dimer signaling specificity in plant immunity
Albert_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2113488119 Genome-wide association identifies a missing hydrolase for tocopherol synthesis in plants
Huang_2022_Science_377_eabq3297 Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity
Vishnu_2022_Bioorg.Chem_120_105594 Enzyme engineering improves catalytic efficiency and enantioselectivity of hydroxynitrile lyase for promiscuous retro-nitroaldolase activity
Arnaiz_2022_Plant.Physiol_189_2244 Hydroxynitrile lyase defends Arabidopsis against Tetranychus urticae
Pei_2022_Enzyme.Microb.Technol_153_109915 Catalytically active inclusion bodies (CatIBs) induced by terminally attached self-assembling coiled-coil domains: To enhance the stability of (R)-hydroxynitrile lyase
Huh_2022_Plant.Signal.Behav__2017631 PopP2 interacts with PAD4 in an acetyltransferase activity-dependent manner and affects plant immunity
Hamon-Josse_2022_New.Phytol_235_126 KAI2 regulates seedling development by mediating light-induced remodelling of auxin transport
Alam_2022_Mol.Plant.Pathol__ Opposing effects of MYZUS PERSICAE-INDUCED LIPASE 1 and jasmonic acid influence the outcome of Arabidopsis thaliana-Fusarium graminearum interaction
Kimberlin_2022_Plant.Physiol__ On the initiation of jasmonate biosynthesis in wounded leaves
Burger_2022_Plant.Direct_6_e466 Crystal structure of Arabidopsis DWARF14-LIKE2 (DLK2) reveals a distinct substrate binding pocket architecture
Lameh_2022_Eng.Life.Sci_22_13 Comparative molecular docking and molecular-dynamic simulation of wild-type- and mutant carboxylesterase with BTA-hydrolase for enhanced binding to plastic (article retracted)
Miyazono_2022_Biochem.Biophys.Res.Commun_591_76 Crystal structure and substrate recognition mechanism of the prolyl endoprotease PEP from Aspergillus niger
Arentshorst_2022_Front.Fungal.Biol_3_978845 Utilization of ferulic acid in Aspergillus niger requires the transcription factor FarA and a newly identified Far-like protein (FarD) that lacks the canonical Zn(II)(2)Cys(6) domain
Hu_2022_Org.Lett__ Structure-Guided Regulation in the Enantioselectivity of an Epoxide Hydrolase to Produce Enantiomeric Monosubstituted Epoxides and Vicinal Diols via Kinetic Resolution
Ezema_2022_J.Biomol.Struct.Dyn__1 Bioinformatic characterization of a triacylglycerol lipase produced by Aspergillus flavus isolated from the decaying seed of Cucumeropsis mannii
Liu_2022_Microb.Cell.Fact_21_97 Display of a novel carboxylesterase CarCby on Escherichia coli cell surface for carbaryl pesticide bioremediation
Noby_2022_Int.J.Mol.Sci_23_4703 Structure-Guided Engineering of a Family IV Cold-Adapted Esterase Expands Its Substrate Range
Zhao_2022_Food.Chem_368_130868 Expression and characterization of a novel lipase from Bacillus licheniformis NCU CS-5 for application in enhancing fatty acids flavor release for low-fat cheeses
Zhao_2022_Food.Chem_366_130616 Immobilization of lipase on beta-cyclodextrin grafted and aminopropyl-functionalized chitosan\/Fe(3)O(4) magnetic nanocomposites: An innovative approach to fruity flavor esters esterification
Davari_2022_ChemSusChem__ Polar substitutions on the surface of a lipase substantially improve tolerance in organic solvents
Cui_2022_Methods.Mol.Biol_2397_179 Using Molecular Simulation to Guide Protein Engineering for Biocatalysis in Organic Solvents
Galmes_2022_Chem.Sci_13_4779 Computational design of an amidase by combining the best electrostatic features of two promiscuous hydrolases
Kim_2022_Pestic.Biochem.Physiol_182_105039 Molecular and kinetic characterization of two acetylcholinesterases with particular focus on the roles of two amino acid substitutions (Y390N and F392W) in Bemisia tabaci
Shan_2022_Int.J.Mol.Sci_23_ alpha\/beta-Hydrolase D16B Truncation Results in Premature Sperm Capacitation in Cattle
Marechal_2022_Nat.Commun_13_2380 Formation of thyroid hormone revealed by a cryo-EM structure of native bovine thyroglobulin
Braa_2022_Org.Biomol.Chem__ Access to valuable building blocks by the regio- and enantioselective ring opening of itaconic anhydride by lipase catalysis
Piazzesi_2022_EMBO.Rep__e52606 CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants
Basso_2022_Cell.Host.Microbe__ Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response
Hu_2022_J.Hazard.Mater_425_127752 Design of 2,5-furandicarboxylic based polyesters degraded in different environmental conditions: Comprehensive experimental and theoretical study
Capone_2022_J.Biomol.Struct.Dyn__1 Evidence for a high pK(a) of an aspartic acid residue in the active site of CALB by a fully atomistic multiscale approach
Mangiagalli_2022_Biotechnol.J__e2100712 Short-chain alcohols inactivate an immobilized industrial lipase through two different mechanisms
Alejaldre_2022_Biochemistry__ Tuning Selectivity in CalA Lipase: Beyond Tunnel Engineering
Liu_2022_Biotechnol.Biofuels.Bioprod_15_127 Selfish uptake versus extracellular arabinoxylan degradation in the primary degrader Ruminiclostridium cellulolyticum, a new string to its bow
Lee_2022_Enzyme.Microb.Technol_161_110117 Divergent substrate specificities and regioselectivities of three lipase isoforms from Cordyceps militaris: Combinatorial advantages for entomopathogenicity and prospects as biocatalysts
Bedrossiantz_2022_Sci.Total.Environ__161268 Heart rate and behavioral responses in three phylogenetically distant aquatic model organisms exposed to environmental concentrations of carbaryl and fenitrothion
Borovsky_2022_Biomolecules_12_991 Cloning and Characterization of Drosophila melanogaster Juvenile Hormone Epoxide Hydrolases (JHEH) and Their Promoters
Sokabe_2022_Sci.Signal_15_eabl6179 Endocannabinoids produced in photoreceptor cells in response to light activate Drosophila TRP channels
Hanschke_2022_Front.Aging_3_800153 Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging
Dilokpimol_2022_FEBS.Lett__ Screening of novel fungal Carbohydrate Esterase family 1 enzymes identifies three novel dual feruloyl\/acetyl xylan esterases
Altammar_2022_Int.J.Biol.Macromol__ Characterization of AnCUT3, a plastic-degrading paucimannose cutinase from Aspergillus niger expressed in Pichia pastoris
Mancheno_2022_Microb.Biotechnol_15_648 A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance
Kosiorowska_2022_Sci.Total.Environ_846_157358 Production of PETase by engineered Yarrowia lipolytica for efficient poly(ethylene terephthalate) biodegradation
Kosiorowska_2022_Sci.Total.Environ_831_154841 Metabolic engineering of Yarrowia lipolytica for poly(ethylene terephthalate) degradation
Wang_2022_BMC.Cancer_22_635 Impact of AADAC gene expression on prognosis in patients with Borrmann type III advanced gastric cancer
Sileshi_2022_Pharmgenomics.Pers.Med_15_561 Effect of Genetic Variations in Drug-Metabolizing Enzymes and Drug Transporters on the Pharmacokinetics of Rifamycins: A Systematic Review
Schratter_2022_Metabolites_12_1015 ABHD5-A Regulator of Lipid Metabolism Essential for Diverse Cellular Functions
Llamas-Garcia_2022_ACS.Omega_7_12643 Improved Stability of Human CGI-58 Induced by Phosphomimetic S237E Mutation
Tseng_2022_Sci.Rep_12_2565 Structural and functional insights into ABHD5, a ligand-regulated lipase co-activator
Bricola_2022_Cell.Biochem.Funct__ Aging reduces ABHD5 protein content in the adipose tissue of mice: The reversal effect of exercise
Shahoei_2022_Front.Mol.Biosci_9_935375 Molecular Modeling of ABHD5 Structure and Ligand Recognition
Gupta_2022_J.Biol.Chem__ Human CIDEC transgene improves lipid metabolism and protects against high-fat diet-induced glucose intolerance in mice
Pusch_2022_Metabolites_12_761 alpha\/beta-Hydrolase Domain-Containing 6 (ABHD6)- A Multifunctional Lipid Hydrolase
Golla_2022_Noncoding.RNA_8_21 ABHD11-AS1: An Emerging Long Non-Coding RNA (lncRNA) with Clinical Significance in Human Malignancies
Lu_2022_Clin.Transl.Oncol_24_1124 LncRNA ABHD11-AS1 promotes tumor progression in papillary thyroid carcinoma by regulating EPS15L1\/EGFR signaling pathway
Zhou_2022_Cancers.(Basel)_14_ Pancreatic Cancer Cell-Derived Exosomes Promote Lymphangiogenesis by Downregulating ABHD11-AS1 Expression
Zhu_2022_J.Healthc.Eng_2022_8387458 LncRNA ABHD11-AS1 Participates in the Progression of Cervical Carcinoma by Targeting miR-1254 and Is the Key to the Diagnosis and Treatment of Cervical Carcinoma in the Future
Nguyen_2022_Elife_11_e84279 An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion
Da Silva_2022_J.Med.Chem_65_4649 A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning
Dileep_2022_Int.J.Biol.Macromol_210_172 Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery
Gerlits_2022_Structure_30_1538 Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering
Nachon_2022_Chembiochem_23_e202200456 Grid-type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions
Meden_2022_Eur.J.Med.Chem_230_114248 From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series
Meden_2022_Eur.J.Med.Chem_247_115048 Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead
Meden_2022_Chemrxiv__ Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead
Ikonnikova_2022_J.Pers.Med_12_580 The Influence of the CES1 Genotype on the Pharmacokinetics of Enalapril in Patients with Arterial Hypertension
Ikonnikova_2022_Genes.(Basel)_13_ The Influence of Structural Variants of the CES1 Gene on the Pharmacokinetics of Enalapril, Presumably Due to Linkage Disequilibrium with the Intronic rs2244613
Her_2022_Proteomics__e2200176 Identification of regulatory variants of carboxylesterase 1 (CES1): A proof-of-concept study for the application of the Allele-Specific Protein Expression (ASPE) assay in identifying cis-acting regulatory genetic polymorphisms
Yerrakula_2022_Biotechnol.Genet.Eng.Rev__ Major implications of single nucleotide polymorphisms in human carboxylesterase 1 on substrate bioavailability
Rajendran_2022_J.Biol.Chem_298_102128 A multi-omics analysis reveals that the lysine deacetylase ABHD14B influences glucose metabolism in mammals
Bainbridge_2022_Brain__ Endocannabinoid dysfunction in neurological disease: neuro-ocular DAGLA-related syndrome (NODRS)
Schuele_2022_Sci.Rep_12_633 Regulation of adult neurogenesis by the endocannabinoid-producing enzyme diacylglycerol lipase alpha (DAGLa)
Liu_2022_Nat.Commun_13_3490 Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
Khasabova_2022_Haematologica__ Inhibition of DAGLbeta as a therapeutic target for pain in sickle cell disease
Bjerknes_2022_Front.Neurol_13_1091688 Case report: Pain in anti-DPPX encephalitis
Malloy_2022_Int.J.Mol.Sci_23_9184 Neuronal Roles of the Multifunctional Protein Dipeptidyl Peptidase-like 6 (DPP6)
Lin_2022_BMC.Neurol_22_242 Anti-dipeptidyl-peptidase-like protein 6 encephalitis with pure cerebellar ataxia: a case report
Ye_2022_Mol.Cell_S1097-2765_00395 Activation and closed-state inactivation mechanisms of the human voltage-gated K(V)4 channel complexes
Xiao_2022_BMC.Neurol_22_129 Clinical and imaging analysis to evaluate the response of patients with anti-DPPX encephalitis to immunotherapy
Moore_2022_ACS.Chem.Biol_17_2595 A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells
Carvalho_2022_Angew.Chem.Int.Ed.Engl_61_e202210498 Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9
Cui_2022_Front.Pharmacol_13_1002871 New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors
Bolgi_2022_EMBO.Rep__e54136 Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
Sun_2022_Proc.Natl.Acad.Sci.U.S.A_119_ Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model
Zhang_2022_Clin.Transl.Med_12_e945 FAM135B sustains the reservoir of Tip60-ATM assembly to promote DNA damage response
Liu_2022_Nat.Cancer__ Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress
Wang_2022_J.Clin.Lab.Anal__e24824 LIPG is a novel prognostic biomarker and correlated with immune infiltrates in lung adenocarcinoma
Yang_2022_Cancers.(Basel)_14_3763 A Proof-of-Concept Inhibitor of Endothelial Lipase Suppresses Triple-Negative Breast Cancer Cells by Hijacking the Mitochondrial Function
Therond_2022_Curr.Opin.Lipidol_33_199 Sphingosine-1-phosphate: metabolism, transport, atheroprotection and effect of statin treatment
He_2022_J.Med.Chem_65_2191 Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging
Kemble_2022_PLoS.One_17_e0268590 A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature
Cheng_2022_Acta.Pharmacol.Sin__ A novel monoacylglycerol lipase-targeted (18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network
Della Pietra_2022_Int.J.Mol.Sci_23_ Inhibiting Endocannabinoid Hydrolysis as Emerging Analgesic Strategy Targeting a Spectrum of Ion Channels Implicated in Migraine Pain
Chetoni_2022_Int.J.Pharm__122078 MAGL inhibitor NanoMicellar formulation (MAGL-NanoMicellar) for the development of an antiglaucoma eye drop
Galvani_2022_J.Chem.Inf.Model__ Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency
Benchama_2022_Sci.Rep_12_5328 Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase
Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__ First-in-human in vivo undefined imaging and quantification of monoacylglycerol lipase in the brain: a PET study with (18)F-T-401
He_2022_Eur.J.Med.Chem_243_114750 Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain
Wagner_2022_Metabolites_12_516 KIAA1363-A Multifunctional Enzyme in Xenobiotic Detoxification and Lipid Ester Hydrolysis
Knudsen_2022_Am.J.Physiol.Endocrinol.Metab_322_E63 Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle
Zhai_2022_Bioengineered_13_83 MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN\/AKT pathway
Sohn_2022_Cells_11_ Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers
Zhao_2022_Comput.Math.Methods.Med_2022_4869470 NDRG4 Alleviates Myocardial Infarction-Induced Apoptosis through the JAK2\/STAT3 Pathway
Zhang_2022_Front.Endocrinol.(Lausanne)_13_1067529 Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders
Zhao_2022_ACS.Chem.Neurosci_13_2060 Structural Analysis and Development of Notum Fragment Screening Hits
Steadman_2022_J.Med.Chem_65_562 Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity
Willis_2022_J.Med.Chem_65_7212 Design of a potent, selective and brain penetrant inhibitor of Wnt-deactivating enzyme Notum by optimization of a crystallographic fragment hit
Ma_2022_Dis.Markers_2022_9775699 Association Lp-PLA2 Gene Polymorphisms with Coronary Heart Disease
Tian_2022_J.Pak.Med.Assoc_72_1114 Changes and significance of serum monocyte chemoattractant protein-1 and Lp-PLA2 in patients with hypertension and coronary heart disease
Kamal_2022_Ther.Adv.Chronic.Dis_13_20406223221078757 Novel homozygous mutation of PNLIP gene in congenital pancreatic lipase deficiency: an extended family study
Li_2022_Elife_11_e79736 Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition
Tang_2022_Nature_602_701 Mechanism-based traps enable protease and hydrolase substrate discovery
Adaixo_2022_Nat.Commun_13_61 Cryo-EM structure of native human thyroglobulin
Zhu_2022_Int.J.Mol.Sci_23_ Discovery of the Key Mutation Site Influencing the Thermostability of Thermomyces lanuginosus Lipase by Rosetta Design Programs
Yoon_2022_Pestic.Biochem.Physiol_185_105137 Characterization of molecular and kinetic properties of two acetylcholinesterases from the Colorado potato beetle, Leptinotarsa decemlineata
Shankar_2022_Int.J.Biol.Macromol_229_803 Biochemical characterization, substrate and stereoselectivity of an outer surface putative alpha\/beta hydrolase from the pathogenic Leptospira
Li_2022_Foods_11_4069 Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols
Ji_2022_Appl.Biochem.Biotechnol_194_1290 Synthesis and Characterization of Epoxidized Silkworm Pupae Oil and Its Application as Polyvinyl Chloride
Nikolaivits_2022_J.Hazard.Mater_434_128900 A polyesterase from the Antarctic bacterium Moraxella sp. degrades highly crystalline synthetic polymers
Lam_2022_Mol.Ther.Methods.Clin.Dev_26_413 Therapeutic efficacy of rscAAVrh74.miniCMV.LIPA gene therapy in a mouse model of lysosomal acid lipase deficiency
Ekstrom_2022_ACS.Med.Chem.Lett_13_499 Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures
Lindgren_2022_Chemistry_28_e202200678 Broad-spectrum antidote discovery by untangling the reactivation mechanism of nerve agent inhibited acetylcholinesterase
Nagaoka_2022_Biochem.Pharmacol_195_114842 Arylacetamide deacetylase knockout mice are sensitive to ketoconazole-induced hepatotoxicity and adrenal insufficiency
Li_2022_Cell.Metab__ Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis
Li_2022_Life.Sci.Alliance_5_ Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice
Eisner_2022_Int.J.Mol.Sci_23_13101 The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1
Ding_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159102 The suppression of pancreatic lipase-related protein 2 ameliorates experimental hepatic fibrosis in mice
Bianchi_2022_J.Phys.Chem.B_126_6820 Toward the Complete Functional Characterization of a Minimal Bacterial Proteome
Xu_2022_PLoS.Pathog_18_e1010615 Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target
Zhang_2022_J.Med.Chem_65_13240 Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment
Wilson_2022_J.Med.Chem_65_409 Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13\; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target
Barelier_2022_FEBS.J__ Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis
Brooks_2022_Biochem.Biophys.Res.Commun_630_57 2.1 A crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1)
Madero-Ayala_2022_Int.J.Mol.Sci_23_12203 In Silico Structural Analysis of Serine Carboxypeptidase Nf314, a Potential Drug Target in Naegleria fowleri Infections
Zong_2022_Nat.Commun_13_1449 Mechanism and biomass association of glucuronoyl esterase: an alpha\/beta hydrolase with potential in biomass conversion
Xiang_2022_Mol.Plant__ An alpha\/beta hydrolase family member negatively regulates salt tolerance but promotes flowering through three distinct functions in rice
Wang_2022_J.Integr.Agric__ OsMas1, a novel maspardin protein gene, confers the tolerance to salt and drought stresses by regulating ABA signaling in rice
Davison_2022_iScience_25_104996 Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targets
Li_2022_J.Integr.Agric_21_1713 Characterization of carboxylesterase PxE8 and its role in multi-insecticide resistance in Plutella xylostella (L.)
Weiler_2022_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1867_159101 A phospholipase B from Pseudomonas aeruginosa with activity towards endogenous phospholipids affects biofilm assembly
Bleffert_2022_eLife_11_e72824 Structural, mechanistic and physiological insights into phospholipase A-mediated membrane phospholipid degradation in Pseudomonas aeruginosa
Yaacob_2022_Int.J.Biol.Macromol__ Structural interpretations of a flexible cold-active AMS8 lipase by combining small-angle X-ray scattering and molecular dynamics simulation (SAXS-MD)
Haryati_2022_Biosci.Rep__ Molecular Characterization of Transesterification Activity of Novel Lipase Family I.1
Li_2022_Front.Bioeng.Biotechnol_10_835847 Two Extracellular Poly(sigma-caprolactone)-Degrading Enzymes From Pseudomonas hydrolytica sp. DSWY01(T): Purification, Characterization, and Gene Analysis
Martinez-Rodriguez_2022_Crystals_12_18 A New L-Proline Amide Hydrolase with Potential Application within the Amidase Process
Terholsen_2022_Chembiochem_23_e202200254 Recovery of hydroxytyrosol from olive mill wastewater using the promiscuous hydrolase\/acyltransferase PestE
Chow_2022_Int.J.Mol.Sci_23_ Rational Design of Lipase ROL to Increase Its Thermostability for Production of Structured Tags
Roh_2022_Food.Chem_385_132705 Enzymatic structural modification of monogalactosyldiacylglycerols for potential modulation of hydrophile-lipophile balance
Wang_2022_Protein.Pept.Lett__ Effect of propeptide mutations on the directed evolution of Rhizomucor miehei lipase
Mishra_2022_Chem.Sci_13_955 A chemical tool for blue light-inducible proximity photo-crosslinking in live cells
Frei_2022_Nat.Methods_19_65 Engineered HaloTag variants for fluorescence lifetime multiplexing
Li_2022_Toxins.(Basel)_14_ Biodegradation of Fumonisins by the Consecutive Action of a Fusion Enzyme
Liu_2022_Food.Addit.Contam.Part.A.Chem.Anal.Control.Expo.Risk.Assess__ FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs
Rmili_2022_J.Biomol.Struct.Dyn__1 Structure elucidation of Staphylococcus capitis lipase. Molecular dynamics simulations to investigate the effects of calcium and zinc ions on the structural stability
Fellner_2022_ADMET.DMPK_10_107 Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
Kiss-Szeman_2022_Chem.Sci_13_14264 A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase-meropenem complex
Kiss-Szeman_2022_Chem.Sci_13_7132 Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad
Haernvall_2022_Front.Bioeng.Biotechnol_10_769830 Residue-Specific Incorporation of the Non-Canonical Amino Acid Norleucine Improves Lipase Activity on Synthetic Polyesters
von Haugwitz_2022_ACS.Catal_12_15259 Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization
Mrigwani_2022_Biotechnol.Bioeng__ Rational mutagenesis of Thermobifida fusca cutinase to modulate the enzymatic degradation of polyethylene terephthalate
Liu_2022_Enzyme.Microb.Technol_156_110004 Enhancement of PET biodegradation by anchor peptide-cutinase fusion protein
Chen_2022_J.Hazard.Mater_433_128816 Directional-path modification strategy enhances PET hydrolase catalysis of plastic degradation
Li_2022_Comput.Struct.Biotechnol.J_20_459 Computational design of a cutinase for plastic biodegradation by mining molecular dynamics simulations trajectories
James_2022_RSC.Adv_12_20563 Cation-pi and hydrophobic interaction controlled PET recognition in double mutated cutinase - identification of a novel binding subsite for better catalytic activity
Gonzalez-Gonzalez_2022_Microorganisms_10_915 Reactivity of a Recombinant Esterase from Thermus thermophilus HB27 in Aqueous and Organic Media
Monic_2022_Sci.Rep_12_4766 A novel lipase with dual localisation in Trypanosoma brucei
Brown_2022_Pathogens_11_1245 Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity
Gong_2022_J.Fungi.(Basel)_8_ Sclerotinia sclerotiorum SsCut1 Modulates Virulence and Cutinase Activity
Kawai_2022_AMB.Express_12_134 Efficient depolymerization of polyethylene terephthalate (PET) and polyethylene furanoate by engineered PET hydrolase Cut190
Haque_2022_Front.Microbiol_13_1060554 Unveiling chlorpyrifos mineralizing and tomato plant-growth activities of Enterobacter sp. strain HSTU-ASh6 using biochemical tests, field experiments, genomics, and in silico analyses
Papanikolaou_2022_Chembiochem__ Bioinformatic evaluation of the substrate specificity exhibited by the highly thermostable esterase EstDZ3
Belanger_2022_FASEB.J_36_e22176 CHARGE syndrome-associated proteins FAM172A and CHD7 influence male sex determination and differentiation through transcriptional and alternative splicing mechanisms
Gao_2022_Folia.Microbiol.(Praha)_67_633 Excavation, expression, and functional analysis of a novel zearalenone-degrading enzyme
Fiorilli_2022_New.Phytol__ A structural homologue of the plant receptor D14 mediates responses to strigolactones in the fungal phytopathogen Cryphonectria parasitica
Gui_2022_J.Am.Chem.Soc__ Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis
Yang_2022_Nat.Genet_54_1553 Improved pea reference genome and pan-genome highlight genomic features and evolutionary characteristics
Mao_2022_Cell.Mol.Gastroenterol.Hepatol__ The CEL-HYB1 Hybrid Allele Promotes Digestive Enzyme Misfolding and Pancreatitis in Mice
Kondoh_2022_Tohoku.J.Exp.Med_256_37 Identification of a Novel Mutation in Carboxyl Ester Lipase Gene in a Patient with MODY-like Diabetes
Renault_2022_Environ.Sci.Pollut.Res.Int__ Predicting the insecticide-driven mutations in a crop pest insect: Evidence for multiple polymorphisms of acetylcholinesterase gene with potential relevance for resistance to chemicals
Mavridis_2022_Pest.Manag.Sci_78_263 Multiple TaqMan qPCR and droplet digital PCR (ddPCR) diagnostics for pesticide resistance monitoring and management, in the major agricultural pest Tetranychus urticae
Nam_2022_Pestic.Biochem.Physiol_182_105033 Insecticide resistance in pepper greenhouse populations of Aphis gossypii (Hemiptera: Aphididae) in Korea
Milesi_2022_Parasit.Vectors_15_484 Evolutionary trade-offs associated with copy number variations in resistance alleles in Culex pipiens mosquitoes
Ngangue-Siewe_2022_Pathogens_11_ Bendiocarb and Malathion Resistance in Two Major Malaria Vector Populations in Cameroon Is Associated with High Frequency of the G119S Mutation (Ace-1) and Overexpression of Detoxification Genes
Khan_2022_Environ.Res__115195 Dysregulation of butyrylcholinesterase, BCHE gene SNP rs1803274, and pro-inflammatory cytokines in occupational workers
Kim_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109524 Short communication: Screening of proof-of-concept mutations of honey bee acetylcholinesterase 2 conferring resistance to organophosphorus and carbamate insecticides
Stalin_2022_Comput.Biol.Med_146_105535 Mosquitocidal efficacy of embelin and its derivatives against Aedes aegypti L. and Culex quinquefasciatus Say. (Diptera: Culicidae) and computational analysis of acetylcholinesterase 1 (AChE1) inhibition
Akay_2022_Protein.J__ Inhibitory Action of Omega-3 and Omega-6 Fatty Acids Alpha-Linolenic, Arachidonic and Linoleic acid on Human Erythrocyte Acetylcholinesterase
Lamie_2022_J.Enzyme.Inhib.Med.Chem_37_2660 Design and synthesis of new indole drug candidates to treat Alzheimer's disease and targeting neuro-inflammation using a multi-target-directed ligand (MTDL) strategy
Gujral_2022_Eur.J.Med.Chem.Rep_6_100075 Design, synthesis and structure-activity relationship studies of 3-phenylpyrazino[1,2-a]indol-1(2H)-ones as amyloid aggregation and cholinesterase inhibitors with antioxidant activity
Mi_2022_Bioorg.Med.Chem.Lett_60_128574 Development of naringenin-O-carbamate derivatives as multi-target-directed liagnds for the treatment of Alzheimer's disease
Carbone_2022_Neurogastroenterol.Motil__e14337 A double-blind randomized, multicenter, placebo-controlled study of itopride in functional dyspepsia postprandial distress syndrome
Yang_2022_ACS.Omega_7_30720 Cation-Exchangeable Pralidoxime Chloride@bio-MOF-1 as a Treatment for Nerve Agent Poisoning and Sulfur Mustard Skin Poisoning in Animals
Bondar_2022_Chem.Biol.Interact__110078 N-substituted arylhydroxamic acids as acetylcholinesterase reactivators
Zhang_2022_J.Diabetes.Investig_13_397 Maternally inherited diabetes and deafness coexists with lipoprotein lipase gene mutation-associated severe hyperlipidemia that was resistant to fenofibrate and atorvastatin, but sensitive to bezafibrate: A case report
Rais_2022_Sci.Adv_8_eabq5925 Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug
Yokoyama_2022_Mol.Cancer.Ther_21_1561 Sirpiglenastat (DRP-104) Induces Antitumor Efficacy through Direct, Broad Antagonism of Glutamine Metabolism and Stimulation of the Innate and Adaptive Immune Systems
Hussain_2022_Chem.Biodivers__ New bis-thiazolidinone based chalcone analogues as effective inhibitors of Alzheimer's disease: Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase study
Li_2022_Eur.J.Med.Chem_244_114841 Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease
Schendel_2022_Front.Plant.Sci_13_951705 2D-HSQC-NMR-Based Screening of Feruloylated Side-Chains of Cereal Grain Arabinoxylans
Shi_2022_Pest.Manag.Sci__ Contribution of multiple overexpressed carboxylesterase genes to indoxacarb resistance in Spodoptera litura
Siddiqui_2022_Molecules_27_ Comprehensive Detoxification Mechanism Assessment of Red Imported Fire Ant (Solenopsis invicta) against Indoxacarb
Ion_2022_Molecules_27_ DES-Based Biocatalysis as a Green Alternative for the l-menthyl Ester Production Based on l-menthol Acylation
Gao_2022_J.Insect.Sci_22_ Resistance to Beta-cypermethrin, Azadirachtin, and Matrine, and Biochemical Characterization of Field Populations of Oedaleus asiaticus (Bey-Bienko) in Inner Mongolia, Northern China
Ejaz_2022_Neurodegener.Dis__ 4-Phthalimidobenzenesulfonamide Derivatives as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: DFTs, 3D-QSAR, ADMET, and Molecular Dynamic Simulation
Yang_2022_Neotrop.Entomol__ Jasmonic Acid-Treated Cotton Plant Leaves Impair Larvae Growth Performance, Activities of Detoxification Enzymes, and Insect Humoral Immunity of Cotton Bollworm
Zhang_2022_Toxins.(Basel)_14_816 Biodegradation of Free Gossypol by Helicoverpa armigera Carboxylesterase Expressed in Pichia pastoris
Loucks_2022_Liver.Int_42_796 Patient-specific genetic factors predict treatment failure in sofosbuvir-treated patients with chronic hepatitis C
Eades_2022_Curr.Drug.Metab__ Covalent CES2 Inhibitors Protect against Reduced Formation of Intestinal Organoids by the Anticancer Drug Irinotecan
Mardon_2022_J.Med.Chem__ Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid alpha\/beta-Hydrolase Domain 6 (ABHD6)
Guo_2022_Eur.J.Med.Chem_242_114630 A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator
Yang_2022_PLoS.One_17_e0278111 Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis
Polonio-Alcala_2022_Biomed.Pharmacother_156_113942 AZ12756122, a novel fatty acid synthase inhibitor, decreases resistance features in EGFR-TKI resistant EGFR-mutated NSCLC cell models
Kumar_2022_J.Forensic.Leg.Med_92_102450 Forensic toxicological and analytical aspects of carbamate poisoning - A review
Turanli_2022_ACS.Omega_7_36354 Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition
Cerqua_2022_J.Med.Chem__ Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX\/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization
Babin_2022_Cell.Chem.Biol_29_897 Identification of covalent inhibitors that disrupt M. tuberculosis growth by targeting multiple serine hydrolases involved in lipid metabolism
Li_2022_Cell.Chem.Biol_29_883 Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling
Qian_2022_Chem.Biol.Interact__110228 Involvement of esterases in the pulmonary metabolism of beclomethasone dipropionate and the potential influence of cannabis use
Richter_2022_Drug.Test.Anal__ In vitro metabolic fate of the synthetic cannabinoid receptor agonists QMMSB (quinolin-8-yl 4-methyl-3-(morpholine-4-sulfonyl)benzoate) and QMiPSB (quinolin-8-yl 4-methyl-3-[(propan-2-yl)sulfamoyl]benzoate) including isozyme mapping and carboxylesterases activity testing
Liu_2022_Bioorg.Chem_129_106168 Discovery of novel beta-carboline-1,2,3-triazole hybrids as AChE\/GSK-3beta dual inhibitors for Alzheimer's disease treatment
Jin_2022_Chem.Biol.Interact_368_110197 Deciphering the species differences in CES1A-mediated hydrolytic metabolism by using a bioluminescence substrate
Imai_2022_Biol.Pharm.Bull_45_1544 Esterases Involved in the Rapid Bioconversion of Esmolol after Intravenous Injection in Humans
Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605 Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
Spatz_2022_RSC.Med.Chem_13_944 Novel benzimidazole-based pseudo-irreversible butyrylcholinesterase inhibitors with neuroprotective activity in an Alzheimer's disease mouse model
Javed_2022_RSC.Adv_12_22503 Diclofenac derivatives as concomitant inhibitors of cholinesterase, monoamine oxidase, cyclooxygenase-2 and 5-lipoxygenase for the treatment of Alzheimer's disease: synthesis, pharmacology, toxicity and docking studies
Rizk_2022_Parasit.Vectors_15_329 Repurposing of the Malaria Box for Babesia microti in mice identifies novel active scaffolds against piroplasmosis
Lucero_2022_Angew.Chem.Int.Ed.Engl__ Activity-based Photoacoustic Probes Reveal Elevated Intestinal MGL and FAAH Activity in a Murine Model of Obesity
Lu_2022_Eur.J.Med.Chem_243_114729 Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease
Kang_2022_Exp.Appl.Acarol__ Acaricidal potential of active components derived from Alpinia galanga rhizome oils and their derivatives against Haemaphysalis longicornis (Acari: Ixodidae)
Rada_2022_ACS.Chem.Neurosci__ Novel Multipotent Amantadine-M30D Hybrids with Highly Selective Butyrylcholinesterase Inhibition and Neuroprotective Effects as Effective Anti-Alzheimer's Agents
Lenina_2022_Sci.Rep_12_1688 Balanced modulation of neuromuscular synaptic transmission via M1 and M2 muscarinic receptors during inhibition of cholinesterases
Selvy_2022_Biomed.Pharmacother_149_112915 Analgesic and preventive effects of donepezil in animal models of chemotherapy-induced peripheral neuropathy: Involvement of spinal muscarinic acetylcholine M2 receptors
Kwon_2022_Medicina.(Kaunas)_58_ Comparison of the Effect of Sugammadex and Pyridostigmine on Postoperative Catheter-Related Bladder Discomfort: A Retrospective Matched Cohort Analysis
Lang_2022_BMC.Pediatr_22_295 Efficacy and safety of sugammadex for neuromuscular blockade reversal in pediatric patients: an updated meta-analysis of randomized controlled trials with trial sequential analysis
Chang_2022_J.Formos.Med.Assoc__ Sugammadex reversal of muscle relaxant blockade provided less Post-Anesthesia Care Unit adverse effects than neostigmine\/glycopyrrolate
Togioka_2022_Drugs.Aging__ Optimizing Reversal of Neuromuscular Block in Older Adults: Sugammadex or Neostigmine
Zhang_2022_Trials_23_376 Comparison of the effects of neostigmine and sugammadex on postoperative residual curarization and postoperative pulmonary complications by means of diaphragm and lung ultrasonography: a study protocol for prospective double-blind randomized controlled trial
Harrington_2022_Commun.Biol_5_865 Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release
Jia_2022_Front.Nutr_9_935112 Fluorine impairs carboxylesterase 1-mediated hydrolysis of T-2 toxin and increases its chondrocyte toxicity
Cea-Rama_2022_FEBS.J__ Crystal structure of a family VIII beta-lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope
Kocyigit_2022_J.Mol.Struct_1264_ Determination of biological studies and molecular docking calculations of isatin-thiosemicarbazone hybrid compounds
An_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_261_109440 Thiobencarb induces phenotypic abnormalities, apoptosis, and cardiovascular toxicity in zebrafish embryos through oxidative stress and inflammation
Rehfeldt_2022_Int.J.Mol.Sci_23_ Neuroprotective Effect of Luteolin-7-O-Glucoside against 6-OHDA-Induced Damage in Undifferentiated and RA-Differentiated SH-SY5Y Cells
Micheli_2022_Int.J.Mol.Sci_23_8428 Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders
Du_2022_J.Med.Chem__ N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease
Ozsan_2022_Chem.Commun.(Camb)_58_10929 Selective detection of carboxylesterase 2 activity in cancer cells using an activity-based chemiluminescent probe
Liu_2022_Anal.Chim.Acta_1221_340126 A highly sensitive and selective enzyme activated fluorescent probe for in vivo profiling of carboxylesterase 2
Bellas_2022_Environ.Sci.Pollut.Res.Int__ Linking biochemical and individual-level effects of chlorpyrifos, triphenyl phosphate, and bisphenol A on sea urchin (Paracentrotus lividus) larvae
Jiao_2022_Biotechnol.Lett__ Recombinant AcMNPV-gp64-EGFP and synergist triphenyl phosphate, an effective combination against Spodoptera frugiperda
Wallraff_2022_Sci.Total.Environ__152779 Occurrence and in vitro toxicity of organic compounds in urban background PM(2.5)
Qiao_2022_J.Hazard.Mater_424_127417 Fluorescence-activated droplet sorting of PET degrading microorganisms
Wang_2022_New.Phytol__ The tomato cytochrome P450 CYP712G1 catalyses the double oxidation of orobanchol en route to the rhizosphere signalling strigolactone, solanacol
Fornier_2022_J.Nat.Prod__ Noncanonical Strigolactone Analogues Highlight Selectivity for Stimulating Germination in Two Phelipanche ramosa Populations
Moriyama_2022_Biosci.Biotechnol.Biochem_86_998 Identification of 6-epi-heliolactone as a biosynthetic precursor of avenaol in Avena strigosa
Kodama_2022_Nat.Commun_13_3974 An ancestral function of strigolactones as symbiotic rhizosphere signals
Wakabayashi_2022_Nat.Prod.Res_36_2215 Conversion of methyl carlactonoate to heliolactone in sunflower
Babaei_2022_Front.Chem_10_895483 Novel Coumarin-Pyridine Hybrids as Potent Multi-Target Directed Ligands Aiming at Symptoms of Alzheimer's Disease
Mzik_2022_J.Pharm.Biomed.Anal_219_114898 UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data
Xu_2022_Diabetes.Obes.Metab__ Efficacy and safety of DBPR108 (prusogliptin) as an add-on to metformin therapy in patients with type 2 diabetes mellitus: A 24-week, multi-center, randomized, double-blind, placebo-controlled, superiority, phase III clinical trial
Zhang_2022_Bioorg.Chem_125_105844 Carbamate-based N-Substituted tryptamine derivatives as novel pleiotropic molecules for Alzheimer's disease
Wang_2022_Bioorg.Chem_127_105993 Discovery of carbamate-based N-salicyloyl tryptamine derivatives as novel pleiotropic agents for the treatment of Alzheimer's disease
Liu_2022_Eur.J.Med.Chem_229_114044 Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease
Li_2022_Eur.J.Med.Chem_239_114510 A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement
Carotenuto_2022_J.Alzheimers.Dis.Rep_6_235 Association Between the Cholinesterase Inhibitor Donepezil and the Cholinergic Precursor Choline Alphoscerate in the Treatment of Depression in Patients with Alzheimer's Disease
Backer_2022_Toxicol.Appl.Pharmacol_446_116046 Pharmacokinetics of three novel pyridinium aldoxime acetylcholinesterase reactivators in female rats
Kim_2022_Anesth.Pain.Med.(Seoul)_17_1 Remimazolam: pharmacological characteristics and clinical applications in anesthesiology
Onoda_2022_Case.Rep.Anesthesiol_2022_9268454 A New Anesthetic, Remimazolam, Is Useful in the Management of Anesthesia in Patients with Liver Cirrhosis
Pflegr_2022_Pharmaceuticals.(Basel)_15_400 5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study
Elghazawy_2022_ACS.Chem.Neurosci__ Discovery of New 1,3,4-Oxadiazoles with Dual Activity Targeting the Cholinergic Pathway as Effective Anti-Alzheimer Agents
Liu_2022_Eur.J.Med.Chem_235_114305 Novel inhibitors of AChE and Abeta aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease
Guo_2022_Bioanalysis_14_817 LC-MS\/MS assay of fluoropezil and its two major metabolites in human plasma: an application to pharmacokinetic studies
Qian_2022_ResearchSquare__ Safety, tolerability, and pharmacokinetics of fluoropezil (DC20), a novel AChE inhibitor: a singlecenter, phase I study in healthy young and elderly Chinese subjects
Grishchenko_2022_ChemMedChem__e202200080 Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease
Liu_2022_Bioorg.Med.Chem_58_116660 Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer's disease
Ochi_2022_Xenobiotica__1 Bottom-up physiologically based pharmacokinetic modeling for predicting the human pharmacokinetic profiles of the ester prodrug MGS0274 and its active metabolite MGS0008, a metabotropic glutamate 2\/3 receptor agonist
Codony_2022_J.Med.Chem_65_4909 Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Zhang_2022_J.Enzyme.Inhib.Med.Chem_37_629 Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1
Liu_2022_Ageing.Neurodegener.Dis__ A novel neuroprotective cholinesterase-monoamine oxidase inhibitor for treatment of dementia and depression in Parkinson's disease
John_2022_Anal.Chem__ Nontargeted High-Resolution Mass Spectrometric Workflow for the Detection of Butyrylcholinesterase-Derived Adducts with Organophosphorus Toxicants and Structural Characterization of Their Phosphyl Moiety after In-Source Fragmentation
Zhang_2022_Oxid.Med.Cell.Longev_2022_5759626 COX-2\/sEH Dual Inhibitor PTUPB Attenuates Epithelial-Mesenchymal Transformation of Alveolar Epithelial Cells via Nrf2-Mediated Inhibition of TGF-beta1\/Smad Signaling
Liu_2022_Biochem.Pharmacol_204_115224 Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus
Wieckowski_2022_Int.J.Mol.Sci_23_9443 Serotonin 5-HT(6) Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity-Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer's Disease
Almasri_2022_Mol.Pharm_19_1091 Role of Silica Intrawall Microporosity on Abiraterone Acetate Solubilization and In Vivo Oral Absorption
Shen_2022_Drug.Metab.dispos__ The Covid-19 oral drug Molnupiravir is a CES2 substrate: potential drug-drug interactions and impact of CES2 genetic polymorphism in vitro
Zhang_2022_Chem.Biol.Interact_365_110097 In vitro evaluation of the impact of Covid-19 therapeutic agents on the hydrolysis of the antiviral prodrug remdesivir
Ma_2022_J.Pharm.Anal_12_683 Discovery of human pancreatic lipase inhibitors from root of Rhodiola crenulata via integrating bioactivity-guided fractionation, chemical profiling and biochemical assay
Lanz_2022_Vet.J_288_105887 Diagnostic utility and validity of 1,2-o-dilauryl-rac-glycero-3-glutaric acid-(6'-methylresorufin) ester (DGGR) lipase activity in horses with colic
Liu_2022_Int.J.Mol.Sci_23_2525 Theophylline Extracted from Fu Brick Tea Affects the Metabolism of Preadipocytes and Body Fat in Mice as a Pancreatic Lipase Inhibitor
Vicente-Zurdo_2022_Biomedicines_10_1510 Novel Rivastigmine Derivatives as Promising Multi-Target Compounds for Potential Treatment of Alzheimer's Disease
Liao_2022_Foods_11_ Inhibitory Mechanism of Baicalein on Acetylcholinesterase: Inhibitory Interaction, Conformational Change, and Computational Simulation
Zhang_2022_Life.Sci_305_120743 Inhibition of Radix Scutellariae flavones on carboxylesterase mediated activations of prodrugs
Hou_2022_J.Sep.Sci__ An efficient strategy based on two-stage chromatography and in vitro evaluation for rapid screening and isolation of acetylcholinesterase inhibitors from Scutellaria baicalensis Georgi
Adedara_2022_Neurotoxicol__ Kaempferol counteracts toxicity induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in D. melanogaster: An implication of its mitoprotective activity
Maslov_2022_Pharmaceuticals.(Basel)_15_273 Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4)
Zheng_2022_Ecotoxicol.Environ.Saf_232_113251 Impacts of di-(2-ethylhexyl) phthalate on Folsomia candida (Collembola) assessed with a multi-biomarker approach
de Saint Germain_2022_Front.Plant.Sci_13_887347 Expansion of the Strigolactone Profluorescent Probes Repertory: The Right Probe for the Right Application
Huang_2022_J.Sci.Food.Agric__ Structure-guided preparation of functional oil rich in 1,3-diacylglycerols and linoleic acid from Camellia oil by combi-lipase
Bradic_2022_Mol.Metab__101510 Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases
Quattrosoldi_2022_Chemosphere_291_132996 Bio-based and one-day compostable poly(diethylene 2,5-furanoate) for sustainable flexible food packaging: Effect of ether-oxygen atom insertion on the final properties
Kim_2022_Vascul.Pharmacol__107086 Soluble epoxide hydrolase inhibitor, TPPU, attenuates progression of atherosclerotic lesions and vascular smooth muscle cell phenotypic switching
Zhang_2022_PLoS.One_17_e0266608 Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor
Bartra_2022_Int.J.Mol.Sci_23_ Neuroprotective Epigenetic Changes Induced by Maternal Treatment with an Inhibitor of Soluble Epoxide Hydrolase Prevents Early Alzheimer's Disease Neurodegeneration
Ma_2022_Metab.Brain.Dis__ Sodium tanshinone IIA sulfonate improves cognitive impairment via regulating Abeta transportation in AD transgenic mouse model
Peng_2022_Eur.J.Pharmacol__174772 Tanshinone IIA regulates glycogen synthase kinase-3beta-related signaling pathway and ameliorates memory impairment in APP\/PS1 transgenic mice
Nguyen_2022_Endocrinol.Metab.(Seoul)__ Gemigliptin Alleviates Succinate-Induced Hepatic Stellate Cell Activation by Ameliorating Mitochondrial Dysfunction
Bhosle_2022_J.Assoc.Physicians.India_70_11 Evaluation of Teneligliptin a DPP4 Inhibitor in Terms of Efficacy and Safety with Respect to QT\/QTc Prolongation in Patients with Type II Diabetes Mellitus (T2DM)
Fronza_2022_Neurochem.Res__ 1-(7-Chloroquinolin-4-yl)-N-(4-Methoxybenzyl)-5-Methyl-1H-1,2, 3-Triazole-4- carboxamide Reduces Abeta Formation and Tau Phosphorylation in Cellular Models of Alzheimer's Disease
Zhang_2022_J.Hazard.Mater_437_129406 Biodegradation of polyester polyurethane by the marine fungus Cladosporium halotolerans 6UPA1
Jamil_2022_Plants.(Basel)_11__ Striga hermonthica Suicidal Germination Activity of Potent Strigolactone Analogs: Evaluation from Laboratory Bioassays to Field Trials
Wakabayashi_2022_Front.Plant.Sci_13_835160 Structure Elucidation and Biosynthesis of Orobanchol
Ogawa_2022_Plant.Signal.Behav_17_2114647 Strigol induces germination of the facultative parasitic plant Phtheirospermum japonicum in the absence of nitrate ions
Ogawa_2022_Nat.Commun_13_4653 Strigolactones are chemoattractants for host tropism in Orobanchaceae parasitic plants
Ren_2022_Int.J.Mol.Sci_23_8274 Lysophosphatidylcholine: Potential Target for the Treatment of Chronic Pain
Dierkes_2022_Appl.Environ.Microbiol__e0160322 An Ultra-Sensitive Comamonas thiooxidans Biosensor for the Rapid Detection of Enzymatic Polyethylene Terephthalate (PET) Degradation
Buchholz_2022_Proteins_90_1443 Plastics degradation by hydrolytic enzymes: The plastics-active enzymes database-PAZy
Dai_2022_Luminescence__ A fast fluorescent probe for tracing endoplasmic reticulum-located carboxylesterase in living cells
Kailass_2022_J.Med.Chem__ Two-Photon Photodynamic Therapy Targeting Cancers with Low Carboxylesterase 2 Activity Guided by Ratiometric Fluorescence
Du_2022_Acta.Pharm.Sin.B_12_1377 Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain
Fang_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2208855119 Unexpected role for IGF-1 in starvation: Maintenance of blood glucose
Zhang_2022_Biomed.Pharmacother_155_113704 The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1\/AKT pathway
Listos_2022_Molecules_27_ Linagliptin, a Selective Dipeptidyl Peptidase-4 Inhibitor, Reduces Physical and Behavioral Effects of Morphine Withdrawal
Benramdane_2022_ChemMedChem__e202200097 Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8\/9-Specific Lead
Huang_2022_Oxid.Med.Cell.Longev_2022_2586305 Sitagliptin Alleviates Radiation-Induced Intestinal Injury by Activating NRF2-Antioxidant Axis, Mitigating NLRP3 Inf--lammasome Activation, and Reversing Gut Microbiota Disorder
Famurewa_2022_Drug.Res.(Stuttg)__ Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Exhibits Antioxidant Mechanism for Abrogation of Cyclophosphamide-Induced Cardiac Damage and Oxidative Hepatorenal Toxicity in Rats
da Cruz Freire_2022_3.Biotech_12_344 Evaluation of the anti-diabetic drug sitagliptin as a novel attenuate to SARS-CoV-2 evidence-based in silico: molecular docking and molecular dynamics
Sharma_2022_Cureus_14_e30077 A Rare Case Report of Sitagliptin-Induced Angioedema
Lu_2022_Xenobiotica_52_38 The metabolism and excretion of the dipeptidyl peptidase 4 inhibitor [(14)C] cetagliptin in healthy volunteers
Lu_2022_Xenobiotica_52_468 Disposition study of the novel dipeptidyl peptidase 4 inhibitor cetagliptin in rats
Lu_2022_Br.J.Clin.Pharmacol_88_2946 A double-blind, randomized, placebo and positive-controlled study in healthy volunteers to evaluate pharmacokinetic and pharmacodynamic properties of multiple oral doses of cetagliptin
Laizure_2022_Drug.Metab.Pharmacokinet_47_100479 Carboxylesterase-2 plays a critical role in dabigatran etexilate active metabolite formation
Qian_2022_Drug.Metab.Dispos__ Prediction of Carboxylesterase 1 (CES1)-mediated In Vivo Drug Interaction between Methylphenidate and Cannabinoids using Static and Physiologically Based Pharmacokinetic Models
Xiao_2022_J.Pharm.Sci__ Physiologically-based pharmacokinetic modeling to predict methylphenidate exposure affected by interplay among carboxylesterase 1 pharmacogenetics, drug-drug interactions, and sex
Arvidsson_2022_Basic.Clin.Pharmacol.Toxicol__ Plasma Concentrations of Methylphenidate Enantiomers in Adults with ADHD and Substance Use Disorder, with focus on high doses and relationship to Carboxylesterase activity
Zhou_2022_Front.Neurosci_16_861059 Diprotin A TFA Exerts Neurovascular Protection in Ischemic Cerebral Stroke
Bajaj_2022_ACS.Chem.Neurosci__ Effect of the MAGL\/FAAH Dual Inhibitor JZL-195 on Streptozotocin-Induced Alzheimer's Disease-like Sporadic Dementia in Mice with an Emphasis on Abeta, HSP-70, Neuroinflammation, and Oxidative Stress
Khara_2022_J.Exp.Biol__ Inhibiting the endocannabinoid degrading enzymes FAAH and MAGL during zebrafish embryogenesis alters sensorimotor function
Toyama_2022_Pharmaceutics_14_ Gallic Acid as a Non-Selective Inhibitor of alpha\/beta-Hydrolase Fold Enzymes Involved in the Inflammatory Process: The Two Sides of the Same Coin
De Koning_2022_ACS.Appl.Mater.Interfaces_14_9222 Effective Degradation of Novichok Nerve Agents by the Zirconium Metal-Organic Framework MOF-808
Mirbabaei_2022_Anal.Bioanal.Chem__ Unambiguous identification and determination of A234-Novichok nerve agent biomarkers in biological fluids using GC-MS\/MS and LC-MS\/MS
Noga_2022_Arch.Toxicol__ What do we currently know about Novichoks? The state of the art
Santos_2022_Arch.Toxicol__ Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?
Liu_2022_Anal.Chem_94_8625 Activity-Based Protein Profiling Probe for the Detection of Enzymes Catalyzing Polysorbate Degradation
Nguyen_2022_J.Nat.Med__ Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum in olfactory bulbectomized mice
He_2022_J.Agric.Food.Chem__ Comprehensive Enantioselectivity Evaluation of Insecticidal Activity and Mammalian Toxicity of Fenobucarb
Lenski_2022_Toxicol.Res.(Camb)_11_529 Aldicarb-related suicide attempt cases in North of France (2012-2021)
Passos_2022_Sci.Total.Environ__155471 Response of Oreochromis niloticus (Teleostei: Cichlidae) exposed to a guanitoxin-producing cyanobacterial strain using multiple biomarkers
Saifina_2022_Eur.J.Med.Chem_246_114949 Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning
Redman_2022_Br.J.Pharmacol__ Donepezil inhibits neuromuscular junctional acetylcholinesterase and enhances synaptic transmission and function in isolated skeletal muscle
Barkae_2022_Sensors.(Basel)_22_ Highly Sensitive Detection of the Insecticide Azamethiphos by Tris(2,2'-bipyridine)ruthenium(II) Electrogenerated Chemiluminescence
Kempuraj_2022_Exp.Eye.Res__109355 Carbofuran pesticide toxicity to the eye
Mosier_2022_Int.J.Sc.Res.Environ.Sci.Toxicol_5_1 Inhibition of Serum Esterases in Juvenile Rats Repeatedly Exposed to Low Levels of Chlorpyrifos
Li_2022_Toxicol.Lett_358_100 Effects of chlorpyrifos on transient receptor potential channels
Ibrahim_2022_Cureus_14_e31497 A Rare Presentation of Severe Organophosphate Poisoning: A Case Report and Review of Literature
Tallini_2022_Plants.(Basel)_11_ Chemical Survey of Three Species of the Genus Rauhia Traub (Amaryllidaceae)
Bykov_2022_Sex.Med_10_100477 Ipidacrine (Axamon), A Reversible Cholinesterase Inhibitor, Improves Erectile Function in Male Rats With Diabetes Mellitus-Induced Erectile Dysfunction
Biancardi_2022_Toxics_10_ Acetylcholinesterase (AChE) Reversible Inhibitors: The Role of Oxamyl in the Production of Poisoned Baits
Simonelli_2022_Toxics_10_ Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature
Zellner_2022_Front.Pharmacol_13_1102160 A case report of severe pirimiphos-methyl intoxication: Clinical findings and cholinesterase status
Martinez-Mercado_2022_Crit.Rev.Toxicol__1 Temephos, an organophosphate larvicide for residential use: a review of its toxicity
Gao_2022_Sci.Total.Environ_815_152853 Similarities and differences among the responses to three chlorinated organophosphate esters in earthworm: Evidences from biomarkers, transcriptomics and metabolomics
Nazarian_2022_Heliyon_8_e10336 Solvent-dependent activity of Candida antarctica lipase B and its correlation with a regioselective mono aza-Michael addition - experimental and molecular dynamics simulation studies
Zhou_2022_J.Med.Entomol__ Emerging Mosquito Resistance to Piperonyl Butoxide-Synergized Pyrethroid Insecticide and Its Mechanism
Silalahi_2022_PLoS.Negl.Trop.Dis_16_e0010501 Insecticide Resistance Profiles and Synergism of Field Aedes aegypti from Indonesia
Zhou_2022_Front.Physiol_13_873580 Juvenile Hormone Is an Important Factor in Regulating Aspongopus chinensis Dallas Diapause
Tiepolt_2022_J.Nucl.Med_63_33S PET Imaging of Cholinergic Neurotransmission in Neurodegenerative Disorders
Zorbaz_2022_Eur.J.Med.Chem_238_114377 Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
Karasova_2022_Food.Chem.Toxicol__113236 Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870
Roberts_2022_J.Cell.Sci_135_ Characterization of lipoprotein lipase storage vesicles in 3T3-L1 adipocytes
Huang_2022_Methods.Mol.Biol_2303_251 Affinity Purification of Glycosylphosphatidylinositol-anchored Proteins by Alpha-Toxin
Sanchis_2022_Amino.Acids_54_181 Rational design and synthesis of modified natural peptides from Boana pulchella (anura) as acetylcholinesterase inhibitors and antioxidants
Upadhyay_2022_J.Mol.Struct_1247_ Influence of ligand geometry on cholinesterase enzyme - A comparison of 1-isoindolinone based structural analog with Donepezil
Santana_2022_Sci.Total.Environ_804_150188 Can the toxicity of polyethylene microplastics and engineered nanoclays on flatfish (Solea senegalensis) be influenced by the presence of each other?
Meng_2022_Sci.Total.Environ_805_150373 Acute warming increases pesticide toxicity more than transgenerational warming by reducing the energy budget
Yin_2022_Anal.Chim.Acta_1190_339248 Development of an esterase fluorescent probe based on naphthalimide-benzothiazole conjugation and its applications for qualitative detection of esterase in orlistat-treated biosamples
Albayrak_2022_Pestic.Biochem.Physiol_180_104984 Pirimicarb resistance and associated mechanisms in field-collected and selected populations of Neoseiulus californicus
Fischer_2022_Adipocyte_11_28 Lysosomal acid lipase promotes endothelial proliferation in cold-activated adipose tissue
Koc_2022_Pestic.Biochem.Physiol_180_104985 Biochemical and molecular mechanisms of acaricide resistance in Dermanyssus gallinae populations from Turkey
Thunen_2022_Adipocyte_11_11 Role of lncRNA LIPE-AS1 in adipogenesis
Alshehri_2022_Neurotox.Res__ Anti-Huntington's Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action
Gazmeh_2022_Metab.Brain.Dis__ Apelin-13 protects against memory impairment and neuronal loss, Induced by Scopolamine in male rats
Hosseini_2022_Metab.Brain.Dis__ Effect of Sanguisorba minor on scopolamine-induced memory loss in rat: involvement of oxidative stress and acetylcholinesterase
Jiang_2022_Brain.Behav__e2469 Diverse myopathological features in the congenital myasthenia syndrome with GFPT1 mutation
Liu_2022_Anal.Chem_94_583 Light-Addressable Paper-Based Photoelectrochemical Analytical Device with Tunable Detection Throughput for On-Site Biosensing
Maruta_2022_Immunogenetics__ Structural basis of NLR activation and innate immune signalling in plants
Okudan_2022_Neurochem.Res__ Potential Protective Effect of Coenzyme Q10 on Doxorubicin-Induced Neurotoxicity and Behavioral Disturbances in Rats
Rastegar-Moghaddam_2022_Naunyn.Schmiedebergs.Arch.Pharmacol__ The effects of vitamin D on learning and memory of hypothyroid juvenile rats and brain tissue acetylcholinesterase activity and oxidative stress indicators
Wei_2022_Eur.J.Clin.Invest__e13741 Predictive value of serum cholinesterase in the mortality of acute pancreatitis: A retrospective cohort study
Abadia_2022_Sci.Total.Environ_815_152841 Hazardous effects of road-side soils on the redox and cholinesterasic homeostasis of mound-building termite (Cornitermes cumulans)
Abraham_2022_Appl.Biochem.Biotechnol__1 In Silico Molecular Docking Approach Against Enzymes Causing Alzheimer's Disease Using Borassus flabellifer Linn
Alipanah_2022_Environ.Toxicol__ Subacute toxicity of chlorpyrifos on histopathological damages, antioxidant activity, and pro-inflammatory cytokines in the rat model
Azhar_2022_CNS.Drugs__ Pharmacological Management of Apathy in Dementia
Baali_2022_Environ.Sci.Process.Impacts__ Effects of carbamazepine in aquatic biota
Bailey_2022_BMC.Genomics_23_45 A scaffold-level genome assembly of a minute pirate bug, Orius laevigatus (Hemiptera: Anthocoridae), and a comparative analysis of insecticide resistance-related gene families with hemipteran crop pests
Cakmak_2022_Arch.Pharm.(Weinheim)__e2100430 Synthesis, characterization, and biological evaluation of some novel Schiff bases as potential metabolic enzyme inhibitors
Camporesi_2022_EBioMedicine_75_103793 Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry
Chien_2022_Langmuir__ Localized Surface Plasmon Resonance-Based Colorimetric Assay Featuring Thiol-Capped Au Nanoparticles Combined with a Mobile Application for On-Site Parathion Organophosphate Pesticide Detection
de Oliveira_2022_Psychopharmacology.(Berl)__1 Prospecting for a quinoline containing selenium for comorbidities depression and memory impairment induced by restriction stress in mice
Delanghe_2022_Clin.Chem.Lab.Med__ Pancreatic lipase assays: time for a change towards immunoassays?
Dhingra_2022_Mini.Rev.Med.Chem__ Imidazole: Multi-targeted Therapeutic Leads for the Management of Alzheimer's Disease
Djouonkep_2022_Molecules_27_ Synthesis of High Performance Thiophene-Aromatic Polyesters from Bio-Sourced Organic Acids and Polysaccharide-Derived Diol: Characterization and Degradability Studies
Eddleston_2022_Br.J.Clin.Pharmacol__ CON: Oximes should be used routinely in organophosphorus insecticide poisoning
Firdaus_2022_Biol.Trace.Elem.Res__ Centella asiatica Alleviates AlCl(3)-induced Cognitive Impairment, Oxidative Stress, and Neurodegeneration by Modulating Cholinergic Activity and Oxidative Burden in Rat Brain
Gajic_2022_ChemMedChem__ Repurposing of 8-Hydroxyquinoline-based Butyrylcholinesterase and Cathepsin B Ligands as Potent Non-peptidic Deoxyribonuclease I Inhibitors
Gammie_2022_Sci.Rep_12_108 Evaluation of animal model congruence to human depression based on large-scale gene expression patterns of the CNS
Gao_2022_Sci.Rep_12_188 Interrelationship between 2019-nCov receptor DPP4 and diabetes mellitus targets based on protein interaction network
Garcia-Garcia_2022_Chem.Commun.(Camb)__ A gliclazide complex based on palladium towards Alzheimer's disease: promising protective activity against Abeta-induced toxicity in C. elegans
Gulcin_2022_Chem.Biodivers__ Polyphenol Contents, Potential Antioxidant, Anticholinergic and Antidiabetic Properties of Mountain Mint (Cyclotrichium leucotrichum)
Ismail_2022_Nat.Rev.Neurol__ Psychosis in Alzheimer disease - mechanisms, genetics and therapeutic opportunities
Karatas_2022_Chem.Biodivers__ Phytochemical contents of different parts of the seeded raisins from the South-East Anatolia: Enzyme inhibitory potential of pulp extracts
Kim_2022_PLoS.One_17_e0262223 Detection of Acanthamoeba spp. using carboxylesterase antibody and its usage for diagnosing Acanthamoeba-keratitis
Lan_2022_J.Environ.Sci.Health.B__1 Nematicidal activity of tirotundin and parthenolide isolated from Tithonia diversifolia and Chrysanthemum parthenium
Lin_2022_Mol.Med.Rep_25_ Knockdown of DPP4 promotes the proliferation and the activation of the CREB\/aromatase pathway in ovarian granulosa cells
Lunic_2022_Plants.(Basel)_11_ The Influence of Seasonality on Secondary Metabolite Profiles and Neuroprotective Activities of Moss Hypnum cupressiforme Extracts: In Vitro and In Silico Study
Mayer_2022_J.Clin.Oncol__JCO2101918 Treatment Exposure and Discontinuation in the PALbociclib CoLlaborative Adjuvant Study of Palbociclib With Adjuvant Endocrine Therapy for Hormone Receptor-Positive\/Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer (PALLAS\/AFT-05\/ABCSG-42\/BIG-14-03)
Michiba_2022_Drug.Metab.Dispos__ Usefulness of human jejunal spheroid-derived differentiated intestinal epithelial cells for the prediction of intestinal drug absorption in humans
Mineur_2022_Mol.Psychiatry_27_1829 Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs
Ortiz-Zamora_2022_Recent.Pat.Biotechnol__ Potential implications of vouacapan compounds for insecticidal activity: an in silico study
Raka_2022_Saudi.J.Biol.Sci_29_239 Synthesis, characterization and in vitro, in vivo, in silico biological evaluations of substituted benzimidazole derivatives
Saad-Hussein_2022_Arch.Environ.Occup.Health__1 Influence of GSTM1, T1 genes polymorphisms on oxidative stress and liver enzymes in rural and urban pesticides-exposed workers
Samad_2022_Saudi.J.Biol.Sci_29_601 Vitamin D2 protects acute and repeated noise stress induced behavioral, biochemical, and histopathological alterations: Possible antioxidant effect
Suleman_2022_BMC.Complement.Med.Ther_22_4 Neuroprotective effects of Lippia javanica (Burm.F.) Spreng. Herbal tea infusion on Lead-induced oxidative brain damage in Wistar rats
Sulkowska-Ziaja_2022_Molecules_27_ Bioactivity and Mycochemical Profile of Extracts from Mycelial Cultures of Ganoderma spp
Taha_2022_J.Biomol.Struct.Dyn__1 Synthesis, in vitro biological screening and docking study of benzo[d]oxazole bis Schiff base derivatives as a potent anti-Alzheimer agent
Zhu_2022_Theor.Appl.Genet__ Fine mapping of powdery mildew resistance gene MlWE74 derived from wild emmer wheat (Triticum turgidum ssp. dicoccoides) in an NBS-LRR gene cluster
Amprosi_2022_Front.Neurol_12_799953 Mast Syndrome Outside the Amish Community: SPG21 in Europe
Alvez_2022_Cell.Mol.Neurobiol__ Effect of Thiazolidin-4-one Against Lipopolysaccharide-Induced Oxidative Damage, and Alterations in Adenine Nucleotide Hydrolysis and Acetylcholinesterase Activity in Cultured Astrocytes
Bakala-N'Goma_2022_Biochimie__ The digestion of diacylglycerol isomers by gastric and pancreatic lipases and its impact on the metabolic pathways for TAG re-synthesis in enterocytes
Colvin_2022_Vet.Parasitol.Reg.Stud.Reports_27_100662 Prevalence of sheep lice and trends in control practices across Australia - Australian sheep parasite control surveys from 2003 to 2019
Deng_2022_Sci.Total.Environ_817_153007 Enantioselective bioaccumulation and toxicity of rac-sulfoxaflor in zebrafish (Danio rerio)
Elizalde-Velazquez_2022_Sci.Total.Environ__153095 Chronic exposure to environmentally relevant concentrations of guanylurea induces neurotoxicity of Danio rerio adults
Elsayed_2022_Environ.Pollut__118821 Estimation of kinetic constants in high-density polyethylene bead degradation using hydrolytic enzymes
Khongkarat_2022_PeerJ_10_e12722 First report of fatty acids in Mimosadiplotricha bee pollen with in vitro lipase inhibitory activity
Li_2022_Annu.Rev.Entomol_67_1 Pest Biological Control: Goals Throughout My Life
Li_2022_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1190_123101 A sensitive approach for screening acetylcholinesterase inhibition of water samples using ultra-performance liquid chromatography-tandem mass spectrometry
Meshkatalsadat_2022_Mol.Divers__ Green and four-component cyclocondensation synthesis and in silico docking of new polyfunctionalized pyrrole derivatives as the potential anticholinesterase agents
Mitusinska_2022_Comput.Struct.Biotechnol.J_20_193 Structure-function relationship between soluble epoxide hydrolases structure and their tunnel network
Nascimento_2022_Chemosphere__133632 Steel wools microfibers causes iron overload and induces biochemical changes in Gallus gallus domesticus chicks (Galliformes: Phasianidae)
Noui_2022_Nat.Prod.Res__1 HPLC-DAD-ESI\/MS profiles of bioactive compounds, antioxidant and anticholinesterase activities of Ephedra alata subsp. alenda growing in Algeria
Sagiv_2022_Environ.Health_21_8 Prenatal exposure to organophosphate pesticides and risk-taking behaviors in early adulthood
Sharma_2022_Biol.Trace.Elem.Res__ Impact of Chronic Sodium Fluoride Toxicity on Antioxidant Capacity, Biochemical Parameters, and Histomorphology in Cardiac, Hepatic, and Renal Tissues of Wistar Rats
Shi_2022_Eur.J.Med.Chem_230_114098 Development of novel 2-aminoalkyl-6-(2-hydroxyphenyl)pyridazin-3(2H)-one derivatives as balanced multifunctional agents against Alzheimer's disease
Silveri_2022_Talanta_240_123212 Modular graphene mediator film-based electrochemical pocket device for chlorpyrifos determination
Som_2022_Metab.Brain.Dis__ Neuroprotective role of Diosgenin, a NGF stimulator, against Abeta (1-42) induced neurotoxicity in animal model of Alzheimer's disease
Sombatsawat_2022_Sci.Rep_12_499 Pesticide toxicity assessment and geographic information system (GIS) application in small-scale rice farming operations, Thailand
Tan_2022_3.Biotech_12_22 Enhancing the methanol tolerance of Candida antarctica lipase B by saturation mutagenesis for biodiesel preparation
Thiermann_2022_Br.J.Clin.Pharmacol__ Oximes should be used routinely in organophosphate poisoning
Vannur_2022_Metab.Brain.Dis__ Experimental validation of Vitex negundo leaves hydroalcoholic extract for neuroprotection in haloperidol induced parkinson's disease in rat
Yan_2022_Anal.Chim.Acta_1191_339362 Peroxidase-like activity of Ru-N-C nanozymes in colorimetric assay of acetylcholinesterase activity
Zaazaa_2022_Heliyon_8_e08622 Stem cell-derived exosomes and copper sulfide nanoparticles attenuate the progression of neurodegenerative disorders induced by cadmium in rats
Zhang_2022_Food.Sci.Nutr_10_3 Hepatitis B virus genotype is an independent prognostic factor of telbivudine and tenofovir treatment in hepatitis B surface antigen-positive pregnant women
Zhang_2022_Mol.Pharm__ Enzyme-Activated Multifunctional Prodrug Combining Site-Specific Chemotherapy with Light-Triggered Photodynamic Therapy
Abdel-Rasoul_2022_Environ.Sci.Pollut.Res.Int__ Respiratory, hepatic, renal, and hematological disorders among adolescent females environmentally exposed to pesticides, Menoufia governorate, Egypt
Adeowo_2022_Mol.Divers__ Pharmacophore mapping of the crucial mediators of acetylcholinesterase and butyrylcholinesterase dual inhibition in Alzheimer's disease
Antunes_2022_Metab.Brain.Dis__ Airway inflammation induces anxiety-like behavior through neuroinflammatory, neurochemical, and neurometabolic changes in an allergic asthma model
Bizzozero_2022_Cells_11_ Tumoral Neuroligin 1 Promotes Cancer-Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor
Calva_2022_Pharm.Biol_60_206 Chemical composition, enantiomeric analysis and anticholinesterase activity of Lepechinia betonicifolia essential oil from Ecuador
Canizares-Carmenate_2022_SAR.QSAR.Environ.Res_33_49 Ligand-based discovery of new potential acetylcholinesterase inhibitors for Alzheimer's disease treatment
Dall'Acqua_2022_Antioxidants.(Basel)_11_ An Integrated NMR, LC-DAD-MS, LC-QTOF Metabolomic Characterization of Sartoria hedysaroides: Correlation of Antioxidant and Enzyme Inhibitory Activity with Chemical Composition by Multivariate Data Analysis
Dhuguru_2022_Pharmaceuticals.(Basel)_15_ FDA-Approved Oximes and Their Significance in Medicinal Chemistry
Dondossola_2022_Neurotoxicol__ Prolonged fluoride exposure alters neurotransmission and oxidative stress in the zebrafish brain
El Harrar_2022_Comput.Struct.Biotechnol.J_20_399 Critical assessment of structure-based approaches to improve protein resistance in aqueous ionic liquids by enzyme-wide saturation mutagenesis
El-Sherbeni_2022_Mol.Cell.Biochem__ Identifying simultaneous matrix metalloproteinases\/soluble epoxide hydrolase inhibitors
Gong_2022_Tohoku.J.Exp.Med_256_19 Monoacylglycerol Lipase (MAGL) Inhibition Impedes the Osteosarcoma Progression by Regulating Epithelial Mesenchymal Transition
Guo_2022_Nat.Prod.Res__1 Phytochemical profiling and antioxidant, enzyme-inhibitory, and toxic activities of extracts from Adonis ramosa Franch
Huang_2022_Ageing.Res.Rev_75_101568 Pharmacological treatments for psychotic symptoms in dementia: A systematic review with pairwise and network meta-analysis
Kopanska_2022_Int.J.Mol.Sci_23_672 Disorders of the Cholinergic System in COVID-19 Era-A Review of the Latest Research
Kos_2022_FEBS.Open.Bio__ Lysosomal peptidases - Intriguing roles in cancer progression and neurodegeneration
Liu_2022_J.Chromatogr.A_1665_462824 Hollow urchin-shaped manganese dioxide microspheres immobilized acetylcholinesterase for rapid screening inhibitors from traditional herbal medicines
McNerney_2022_J.Alzheimers.Dis__ Repetitive Transcranial Magnetic Stimulation Improves Brain-Derived Neurotrophic Factor and Cholinergic Signaling in the 3xTgAD Mouse Model of Alzheimer's Disease
Montaniel_2022_J.Dev.Orig.Health.Dis__1 Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers
Nabulsi_2022_Neuropsychopharmacology__ Normalization of impaired emotion inhibition in bipolar disorder mediated by cholinergic neurotransmission in the cingulate cortex
Phuna_2022_Eur.J.Neurosci__ A closer look at the mycobiome in Alzheimer's disease: Fungal species, pathenogenesis ans transmission
Ran_2022_BMC.Cancer_22_93 Serum cholinesterase may independently predict prognosis in non-small-cell lung cancer
Richter_2022_J.Alzheimers.Dis__ Age and Anterior Basal Forebrain Volume Predict the Cholinergic Deficit in Patients with Mild Cognitive Impairment due to Alzheimer's Disease
Samant_2022_Neurotox.Res_40_140 Avicularin Attenuates Memory Impairment in Rats with Amyloid Beta-Induced Alzheimer's Disease
Shi_2022_Curr.Alzheimer.Res__ Comparative efficacy and acceptability of cholinesterase inhibitors and memantine based on dosage in patients with vascular cognitive impairment: a network meta-analysis
Stojanovic_2022_Cells_11_ Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132\/212 Genes
Wang_2022_Life.Sci_293_120336 Hepatocellular BChE as a therapeutic target to ameliorate hypercholesterolemia through PRMT5 selective degradation to restore LDL receptor transcription
Wei_2022_Water.Res_211_118068 Millions of microplastics released from a biodegradable polymer during biodegradation\/enzymatic hydrolysis
Yang_2022_Phys.Chem.Chem.Phys__ Molecular understanding of acetylcholinesterase adsorption on functionalized carbon nanotubes for enzymatic biosensors
Zhang_2022_Bioorg.Chem_120_105628 In vitro absorption and lipid-lowering activity of baicalin esters synthesized by whole-cell catalyzed esterification
Aboulthana_2022_Asian.Pac.J.Cancer.Prev_23_287 Assessment of the Biological Activities of Egyptian Purslane (Portulaca oleracea) Extract after Incorporating Metal Nanoparticles, in Vitro and in Vivo Study
Aibara_2022_Endocr.J__ Lipase family member N is a novel target gene for CCAAT\/enhancer-binding protein alpha in type 2 diabetic model mouse liver
Alavi_2022_Metab.Brain.Dis__ Beneficial effects of levetiracetam in streptozotocin-induced rat model of Alzheimer's disease
Barth_2022_ChemMedChem__ Hexafluoroisopropyl carbamates as selective MAGL and dual MAGL\/FAAH inhibitors: biochemical and physicochemical properties
Chen_2022_Phytochemistry_196_113089 Iboga-type alkaloids with Indolizidino[8,7-b]Indole scaffold and bisindole alkaloids from Tabernaemontana bufalina Lour
El-Safty_2022_Brain.Res.Bull__ Dapagliflozin diminishes memory and cognition impairment in Streptozotocin induced diabetes through its effect on Wnt\/beta-Catenin and CREB pathway
Galassi_2022_Isr.Med.Assoc.J_24_9 Coincidental Onset of Ocular Myasthenia Gravis Following ChAdOx1 n-CoV-19 Vaccine against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Ganeshpurkar_2022_Int.J.Biol.Macromol__ Identification of sulfonamide based butyrylcholinesterase inhibitors through scaffold hopping approach
Gladis_2022_Nucleosides.Nucleotides.Nucleic.Acids__1 Synthesis, structural elucidation, DNA binding, cleavage, AChE and BuChE cholinesterase efficiencies of metal complexes with 1,10-phenanthroline scaffold
Gonzalez_2022_Environ.Toxicol.Chem__ Evaluation of the Acute Effects of Arsenic on Adults of the Neotropical Native Fish Cnesterodon decemmaculatus Using a Set of Biomarkers
Honerkamp_2022_J.Clin.Exp.Hepatol_12_68 Surgical Procedures in Patients Awaiting Liver Transplantation: Complications and Impact on the Liver Function
Hu_2022_Lab.Med__ Serum Metabolomics in Patients with Coexisting NAFLD and T2DM Using Liquid Chromatography-Mass Spectrometry
Karthikeyan_2022_J.Genet.Eng.Biotechnol_20_14 Promising bioactive compounds from the marine environment and their potential effects on various diseases
Lazarova_2022_J.Mol.Neurosci__ Tyrosinyl-amantadine: A New Amantadine Derivative With an Ameliorative Effect in a 6-OHDA Experimental Model of Parkinson's Disease in Rats
Li_2022_Metab.Brain.Dis__ Alzheimer's disease therapy based on acetylcholinesterase inhibitor\/blocker effects on voltage-gated potassium channels
Liu_2022_BMC.Med_20_45 Personalised treatment for cognitive impairment in dementia: development and validation of an artificial intelligence model
Mesa-Herrera_2022_J.Alzheimers.Dis__ Multivariate Assessment of Lipoxidative Metabolites, Trace Biometals, and Antioxidant and Detoxifying Activities in the Cerebrospinal Fluid Define a Fingerprint of Preclinical Stages of Alzheimer's Disease
Munoz-Penuela_2022_Environ.Toxicol.Pharmacol__103821 Neurotoxic, biotransformation, oxidative stress and genotoxic effects in Astyanax altiparanae (Teleostei, Characiformes) males exposed to environmentally relevant concentrations of diclofenac and\/or caffeine
Naseem_2022_BMC.Complement.Med.Ther_22_30 In vitro and in vivo evaluations of antioxidative, anti-Alzheimer, antidiabetic and anticancer potentials of hydroponically and soil grown Lactuca sativa
Ni_2022_J.Orthop.Translat_32_85 Hemodynamic stress shapes subchondral bone in osteoarthritis: An emerging hypothesis
Peter_2022_Pestic.Biochem.Physiol_181_105027 Effect of Illicium verum (Hook) essential oil on cholinesterase and locomotor activity of Alphitobius diaperinus (Panzer)
Punia_2022_Compr.Rev.Food.Sci.Food.Saf__ Recent developments in cold plasma-based enzyme activity (browning, cell wall degradation, and antioxidant) in fruits and vegetables
Rasmussen_2022_J.Colloid.Interface.Sci_614_214 The changing face of SDS denaturation: Complexes of Thermomyces lanuginosus lipase with SDS at pH 4.0, 6.0 and 8.0
Rosales-Perez_2022_Chemosphere__133791 Brain damage induced by contaminants released in a hospital from Mexico: Evaluation of swimming behavior, oxidative stress, and acetylcholinesterase in zebrafish (Danio rerio)
Shabbir_2022_PLoS.One_17_e0263274 Comprehensive profiling of bioactive compounds in germinated black soybeans via UHPLC-ESI-QTOF-MS\/MS and their anti-Alzheimer's activity
Sigacheva_2022_Environ.Sci.Pollut.Res.Int__ Application of biochemical and morphophysiological parameters of round goby Neogobius melanostomus (Pallas, 1814) for assessment of marine ecological state
Silberschmidt_2022_Environ.Pollut_299_118894 Realistic exposure to fipronil, 2,4-D, vinasse and their mixtures impair larval amphibian physiology
Song_2022_Chem.Biol.Interact__109830 Fibroblast activation protein alpha: Comprehensive detection methods for drug target and tumor marker
Thaneefa_2022_Clin.Chim.Acta__ Incidental diagnosis of LPL deficiency in an infant presenting with an acute respiratory infection
Tian_2022_Bioresour.Technol__126769 Improvement of methanol tolerance and catalytic activity of Rhizomucor miehei lipase for one-step synthesis of biodiesel by semi-rational design
Weisbrod_2022_Neurotherapeutics__1 Primary Palliative Care in Dementia
Wyrebek_2022_Neuromuscul.Disord__ Hypotonic infant with PURA syndrome-related channelopathy successfully treated with pyridostigmine
Xiang_2022_Pharmacol.Biochem.Behav__173340 Activation of GPR55 attenuates cognitive impairment, oxidative stress, neuroinflammation, and synaptic dysfunction in a streptozotocin-induced Alzheimer's mouse model
Zhao_2022_Food.Chem_379_132148 Green synthesis of polydopamine functionalized magnetic mesoporous biochar for lipase immobilization and its application in interesterification for novel structured lipids production
Acquaroni_2022_J.Environ.Sci.Health.B__1 Acute, chronic and neurotoxic effects of dimethoate pesticide on Rhinella arenarum throughout the development
Agarwal_2022_Chem.Commun.(Camb)__ The yin and yang of intracellular delivery of amphipathic optical probes using n-butyl charge masking
Aggarwal_2022_Top.Curr.Chem.(Cham)_380_10 Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold
Andrade_2022_J.Clin.Psychiatry_83_22f14398 Methylphenidate and Other Pharmacologic Treatments for Apathy in Alzheimer's Disease
Belviranli_2022_Neurosci.Lett_773_136499 Differential effects of voluntary and forced exercise trainings on spatial learning ability and hippocampal biomarkers in aged female rats
Bohlken_2022_J.Alzheimers.Dis__ Association Between Ginkgo Biloba Extract Prescriptions and Dementia Incidence in Outpatients with Mild Cognitive Impairment in Germany: A Retrospective Cohort Study
Cai_2022_Enzyme.Microb.Technol_155_109992 Nanobodies as binding-chaperones stabilize the recombinant Bombyx mori acetylcholinesterase and protect the enzyme activity in pesticide detection
Chen_2022_J.Oleo.Sci_71_277 Anti-human Glioma Cancer Potentials of Neobavaisoflavone as Natural Antioxidant Compound and Its Inhibition Profiles for Acetylcholinesterase and Butyrylcholinesterase Enzymes with Molecular Modeling and Spin Density Distributions Studies
Chen_2022_J.Pharm.Biomed.Anal_211_114632 Preparation and characterization of immobilized 5-HT(1A) receptor stationary phase for high throughput screening of the receptor-binding ligands from complex systems like Curcuma wenyujin Y. H. Chen et C. Ling extract
Dai_2022_J.Agric.Food.Chem__ Analysis of the Structure and Activity of Dipeptidyl Peptidase IV (DPP-IV) Inhibitory Oligopeptides from Sorghum Kafirin
Duran_2022_Biotechnol.Appl.Biochem__ Pyrimidines: Molecular docking and inhibition studies on carbonic anhydrase and cholinesterases
Dwibedi_2022_Appl.Microbiol.Biotechnol__ Inhibitory activities of grape bioactive compounds against enzymes linked with human diseases
Falade_2022_J.Biomol.Struct.Dyn__1 Computational studies on the cholinesterase, beta-secretase 1 (BACE1) and monoamine oxidase (MAO) inhibitory activities of endophytes-derived compounds: towards discovery of novel neurotherapeutics
Florentino_2022_Brain.Inj__1 Acetylcholinesterase inhibitors to enhance recovery from traumatic brain injury: a comprehensive review and case series
Fontes_2022_Bioorg.Chem_120_105593 Cholinesterase inhibitors assessment of aporphine alkaloids from Annona crassiflora and molecular docking studies
Gao_2022_J.Food.Sci_87_651 Potential of phenolic compounds in Ligustrum robustum (Rxob.) Blume as antioxidant and lipase inhibitors: Multi-spectroscopic methods and molecular docking
Guo_2022_Environ.Sci.Pollut.Res.Int__ Enantioselective acute toxicity, oxidative stress effects, neurotoxicity, and thyroid disruption of uniconazole in zebrafish (Danio rerio)
Haigis_2022_Chemosphere__133863 Getting more out of the zebrafish light dark transition test
He_2022_Environ.Sci.Pollut.Res.Int__ Behavioral, histopathological, genetic, and organism-wide responses to phenanthrene-induced oxidative stress in Eisenia fetida earthworms in natural soil microcosms
Herrmann_2022_Alzheimers.Dement.(N.Y)_8_e12099 CCCDTD5 recommendations on the deprescribing of cognitive enhancers in dementia
Joshi_2022_Acta.Parasitol__ Functional Diversity of the Excretory\/Secretory Proteins of Nematode Parasites
Kobenan_2022_Chem.Biodivers__ Chemical composition, antioxidant activity, cholinesterase inhibitor and in vitro insecticidal potentiality of essential oils of Lippiamultiflora Moldenke and Eucalyptusglobulus Labill. on the main carpophagous pests of cotton plant in Ivory Coast
Lamprou_2022_Int.J.Radiat.Oncol.Biol.Phys__ Lipophagy-related protein perilipin-3 (PLIN3) and resistance of prostate cancer to radiotherapy
Li_2022_J.Food.Biochem__e14068 Network pharmacology-based approach to investigate the mechanisms of Zingiber officinale Roscoe in the treatment of neurodegenerative diseases
Li_2022_ACS.Appl.Bio.Mater__ Molecular Basis of the Reinforced Effect of Berberine against Cutinase from Colletotrichum capsisi by Supplying Sodium Stearate as Dispersant
Mohammadi-Khanaposhtani_2022_Arch.Pharm.(Weinheim)__e2100313 New 4-phenylpiperazine-carbodithioate-N-phenylacetamide hybrids: Synthesis, in vitro and in silico evaluations against cholinesterase and alpha-glucosidase enzymes
Nie_2022_J.Neuroinflammation_19_39 Marine fungal metabolite butyrolactone I prevents cognitive deficits by relieving inflammation and intestinal microbiota imbalance on aluminum trichloride-injured zebrafish
Prasanth_2022_3.Biotech_12_48 Carbohydrate active enzymes (CAZy) regulate cellulolytic and pectinolytic enzymes in Colletotrichum falcatum causing red rot in sugarcane
Ramdass_2022_BMC.Microbiol_22_43 Detection and diversity of the mannosylerythritol lipid (MEL) gene cluster and lipase A and B genes of Moesziomyces antarcticus isolated from terrestrial sites chronically contaminated with crude oil in Trinidad
Shao_2022_Acta.Pharm.Sin.B_12_308 [(18)F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models
Sultzer_2022_Alzheimers.Res.Ther_14_25 Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer's disease dementia
Sunil_2022_Curr.Atheroscler.Rep__ Childhood Hypertriglyceridemia: Is It Time for a New Approach?
Teipel_2022_Eur.J.Neurol__ Ante-mortem basal forebrain atrophy in pure limbic TAR DNA-binding protein 43 pathology compared with pure Alzheimer pathology
Uchida_2022_Hepatol.Res__ Significance of furosemide in patients with cirrhosis treated with or without zinc acetate hydrate supplementation
Wang_2022_Curr.Drug.Metab__ Substrate-dependent inhibition of hypericin on human carboxylesterase 2: implications for herb-drug combination
Xi_2022_Bioorg.Med.Chem.Lett__128602 Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibitors
Xia_2022_FASEB.J_36_e22189 Regulation of acetylcholinesterase during the lipopolysaccharide-induced inflammatory responses in microglial cells
Xiang_2022_Analyst__ An easily available endoplasmic reticulum targeting near-infrared fluorescent probe for esterase imaging in vitro and in vivo
Yildiz_2022_Bioorg.Chem_120_105647 Dimethoxyindoles based thiosemicarbazones as multi-target agents\; synthesis, crystal interactions, biological activity and molecular modeling
Yuan_2022_J.Chromatogr.A_1665_462827 Site-selective covalently immobilized alpha 1A adrenergic receptor for thermodynamic and extra-thermodynamic study of four ligands binding to the receptor by chromatographic methods
Zaid_2022_Microbiol.Spectr__e0216921 Comparative Genome Analysis Reveals Phylogenetic Identity of Bacillus velezensis HNA3 and Genomic Insights into Its Plant Growth Promotion and Biocontrol Effects
Zhang_2022_Evid.Based.Complement.Alternat.Med_2022_4778163 The Effect of Guilingji Capsules on Vascular Mild Cognitive Impairment: A Randomized, Double-Blind, Controlled Trial
Zhang_2022_J.Toxicol.Sci_47_61 Ferulic acid regulates miR-17\/PTEN axis to inhibit LPS-induced pulmonary microvascular endothelial cells apoptosis through activation of PI3K\/Akt pathway
Zhang_2022_Bioprocess.Biosyst.Eng_45_749 Chemical modification for improving catalytic performance of lipase B from Candida antarctica with hydrophobic proline ionic liquid
Zhao_2022_EMBO.Rep__e52669 An RDH-Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase
Alimi_2022_Vet.Parasitol_303_109665 Phytochemistry, anti-tick, repellency and anti-cholinesterase activities of Cupressus sempervirens L. and Mentha pulegium L. combinations against Hyalomma scupense (Acari: Ixodidae)
Al-Maharik_2022_Molecules_27_ Isolation, Identification and Pharmacological Effects of Mandragora autumnalis Fruit Flavonoids Fraction
Alves_2022_Mar.Pollut.Bull_176_113418 Elasmobranchs as bioindicators of pollution in the marine environment
Araujo_2022_Biotechnol.Lett__ Larvicidal activity against Aedes aegypti and molecular docking studies of compounds extracted from the endophytic fungus Aspergillus sp. isolated from Bertholletia excelsa Humn. & Bonpl
Ayoub_2022_Food.Funct__ Insights into the neuroprotective effects of Salvia officinalis L. and Salvia microphylla Kunth in the memory impairment rat model
de Souza_2022_J.Enzyme.Inhib.Med.Chem_37_718 Comparative chemical and biological hydrolytic stability of homologous esters and isosteres
Egba_2022_Avicenna.J.Phytomed_12_42 Buchholzia coriacea seed extract attenuates mercury-induced cerebral and cerebellar oxidative neurotoxicity via NO signaling and suppression of oxidative stress, adenosine deaminase and acetylcholinesterase activities in rats
El-Fattah_2022_Int.J.Mol.Sci_23_ Amphiphilic Pentablock Copolymers Prepared from Pluronic and sigma-Caprolactone by Enzymatic Ring Opening Polymerization
Foyzun_2022_Molecules_27_ Polyphenolics with Strong Antioxidant Activity from Acacia nilotica Ameliorate Some Biochemical Signs of Arsenic-Induced Neurotoxicity and Oxidative Stress in Mice
Ghalloo_2022_Molecules_27_ Phytochemical Profiling, In Vitro Biological Activities, and In Silico Molecular Docking Studies of Dracaena reflexa
Hazarika_2022_Sci.Rep_12_2180 The fabrication and assessment of mosquito repellent cream for outdoor protection
Heysieattalab_2022_Avicenna.J.Phytomed_12_89 Ecballium elaterium attenuates neuroinflammation in an animal model of Alzheimer's disease through modulation of nuclear factor B pathway
John_2022_Metab.Brain.Dis__ Jobelyn extends the life span and improves motor function in Drosophila melanogaster exposed to lipopolysaccharide via augmentation of antioxidant status
Kaur_2022_Micron_155_103225 Ultrastructural studies of photoreceptor cell degeneration with organophosphate and its regeneration in Cyprinus carpio communis L
Kondakala_2022_Toxicol.In.Vitro__105329 Effects of chlorpyrifos on non-cholinergic toxicity endpoints in immortalized and primary rat hepatocytes under normal and hepatosteatotic conditions
Kopanska_2022_Molecules_27_ The Effect of alpha-Tocopherol on the Reduction of Inflammatory Processes and the Negative Effect of Acrylamide
Lam_2022_Int.J.Mol.Sci_23_ Evaluation of the Impact of Esterases and Lipases from the Circulatory System against Substrates of Different Lipophilicity
Le_2022_Anal.Methods__ Extraction of curcumin from turmeric residue (Curcuma longa L.) using deep eutectic solvents and surfactant solvents
Leuci_2022_Molecules_27_ A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)
Li_2022_Sheng.Wu.Gong.Cheng.Xue.Bao_38_207 [Characterization of Humicola insolens cutinase-tachystatin A2 fusion protein and its application in treatment of recycled paper stickies]
Makhaeva_2022_Molecules_27_ Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile
Moreira_2022_J.Ethnopharmacol_289_115089 New dimer and trimer of chalcone derivatives from anti-inflammatory and antinociceptive extracts of Schinopsis brasiliensis roots
Nazari_2022_J.Ethnopharmacol__115050 Palicourea tomentosa (Aubl.) Borhidi: Microscopy, chemical composition and the analgesic, anti-inflammatory and anti-acetylcholinesterase potential
Omori_2022_J.Gastrointest.Surg__ Clinical Benefits of Routine Feeding Jejunostomy Tube Placement in Patients Undergoing Esophagectomy
Popova_2022_Plants.(Basel)_11_ High-Performance Liquid Chromatography-Mass Spectrometry Analysis of Glycoalkaloids from Underexploited Solanum Species and Their Acetylcholinesterase Inhibition Activity
Qin_2022_ACS.Nano__ Iron Single-Atom Catalysts Boost Photoelectrochemical Detection by Integrating Interfacial Oxygen Reduction and Enzyme-Mimicking Activity
Ratnasari_2022_PLoS.One_17_e0263298 Potential plasma biomarkers: miRNA-29c, miRNA-21, and miRNA-155 in clinical progression of Hepatocellular Carcinoma patients
Scheiner_2022_J.Am.Chem.Soc__ Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer's Disease Mouse Model upon Irradiation
Sheibani_2022_Neuropeptides_92_102229 The effects of neurosteroid allopregnanolone on synaptic dysfunction in the hippocampus in experimental parkinsonism rats: An electrophysiological and molecular study
Sirichai_2022_Plants.(Basel)_11_ Impact of Drying Processes on Phenolics and In Vitro Health-Related Activities of Indigenous Plants in Thailand
Sokolowska_2022_Materials.(Basel)_15_ Enzymatic Catalysis in Favor of Blocky Structure and Higher Crystallinity of Poly(Butylene Succinate)-Co-(Dilinoleic Succinate) (PBS-DLS) Copolymers of Variable Segmental Composition
Soumya_2022_Mol.Biotechnol__ An Esterase with Increased Acetone Tolerance from Bacillus subtilis E9 over Expressed in E. coli BL21 Using pTac Bs-est Vector
Targowska-Duda_2022_ChemMedChem__ WaterMap guided structure-based virtual screening for acetylcholinesterase inhibitors
Tuan_2022_Plants.(Basel)_11_ Inhibition of alpha-Glucosidase, Acetylcholinesterase, and Nitric Oxide Production by Phytochemicals Isolated from Millettia speciosa-In Vitro and Molecular Docking Studies
Underwood_2022_Mol.Plant.Microbe.Interact__ Arabidopsis GOLD36\/MVP1\/ERMO3 is required for powdery mildew penetration resistance and proper targeting of the PEN3 transporter
Valarezo_2022_Plants.(Basel)_11_ Enantiomeric Composition, Antioxidant Capacity and Anticholinesterase Activity of Essential Oil from Leaves of Chirimoya (Annona cherimola Mill.)
van der Westhuizen_2022_J.Chem.Inf.Model__ Discovery of Novel Acetylcholinesterase Inhibitors by Virtual Screening, In Vitro Screening, and Molecular Dynamics Simulations
Wei_2022_Metab.Brain.Dis__ Protective effect of Juglanin against doxorubicin-induced cognitive impairment in rats: Effect on oxidative, inflammatory and apoptotic machineries
Wei_2022_Molecules_27_ Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice
Wipf_2022_PLoS.Genet_18_e1009963 Multi-insecticide resistant malaria vectors in the field remain susceptible to malathion, despite the presence of Ace1 point mutations
Yu_2022_Anal.Chem__ Two-Dimensional Cobalt-Doped Ti(3)C(2) MXene Nanozyme-Mediated Homogeneous Electrochemical Strategy for Pesticides Assay Based on In Situ Generation of Electroactive Substances
Zhang_2022_Food.Sci.Nutr_10_487 UHPLC-QTOF\/MS-based comparative metabolomics in pectoralis major of fast- and slow-growing chickens at market ages
Zhang_2022_Food.Chem_382_132302 Lipase-catalyzed one-step regioselective synthesis of 1,2-dioctanoylgalloylglycerol in a solvent-free system: Optimization of reaction conditions and structural elucidation
Asejeje_2022_J.Biochem.Mol.Toxicol__e23010 Sodium benzoate induces neurobehavioral deficits and brain oxido-inflammatory stress in male Wistar rats: Ameliorative role of ascorbic acid
Batool_2022_ACS.Pharmacol.Transl.Sci_5_70 In Silico and Ex Vivo Analyses of the Inhibitory Action of the Alzheimer Drug Posiphen and Primary Metabolites with Human Acetyl- and Butyrylcholinesterase Enzymes
Cao_2022_Food.Chem_381_132282 An efficient multi-enzyme cascade platform based on mesoporous metal-organic frameworks for the detection of organophosphorus and glucose
de Oliveira_2022_Environ.Sci.Pollut.Res.Int__ Essential oil of Piper purusanum C.DC (Piperaceae) and its main sesquiterpenes: biodefensives against malaria and dengue vectors, without lethal effect on non-target aquatic fauna
Dong_2022_Phytochemistry_197_113129 Cirrhosinones A-H, 24-hydroxy cevanine-type alkaloids from Fritillariacirrhosa
Elkhanoufi_2022_Chemistry__ Highly sensitive off\/on EPR probes to monitor enzymatic activity
Fernandes_2022_J.Ethnopharmacol_290_115107 Multi-target neuroprotective effects of herbal medicines for Alzheimer's disease
Gautam_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109299 Metal accumulation and morphofunctional damage in coelomocytes of earthworm collected from industrially contaminated soil of Kolkata, India
Gordon_2022_Bull.Exp.Biol.Med__ Analysis of the Effect of Neuroprotectors That Reduce the Level of Degeneration of Neurons in the Rat Hippocampus Caused by Administration of Beta-Amyloid Peptide Abeta(25-35)
Hamed_2022_Environ.Sci.Pollut.Res.Int__ Alleviation of nicotine-induced reproductive disorder, clastogenicity, and histopathological alterations by fenugreek saponin bulk and nanoparticles in male rats
Hanslik_2022_Aquat.Toxicol_245_106120 Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene
Hegde_2022_Glob.Med.Genet_9_18 Genetic Analysis of Neuroligin 4Y Gene in Autism Population of India
Hines_2022_Mol.Psychiatry__ Human ARHGEF9 intellectual disability syndrome is phenocopied by a mutation that disrupts collybistin binding to the GABA(A) receptor alpha2 subunit
Jackson_2022_J.Mol.Biol_434_167462 Adventures on the routes of protein evolution - in memoriam Dan Salah Tawfik (1955 - 2021)
Jeyavani_2022_Chemosphere__133990 Toxicity evaluation of polypropylene microplastic on marine microcrustacean Artemia salina: An analysis of implications and vulnerability
Kaur_2022_Bioorg.Chem_121_105670 Design, molecular Docking, synthesis and evaluation of xanthoxylin hybrids as dual inhibitors of IL-6 and acetylcholinesterase for Alzheimer's disease
Kaya_2022_J.Biol.Inorg.Chem__ New Pd(II) complexes of the bisthiocarbohydrazones derived from isatin and disubstituted salicylaldehydes: Synthesis, characterization, crystal structures and inhibitory properties against some metabolic enzymes
Lee_2022_Fish.Shellfish.Immunol__ Toxic effects of waterborne cadmium exposure on hematological parameters, oxidative stress, neurotoxicity, and heat shock protein 70 in juvenile olive flounder, Paralichthys olicaceus
Leem_2022_Sci.Rep_12_2852 A network pharmacology-based approach to explore mechanism of action of medicinal herbs for alopecia treatment
Liew_2022_Sci.Rep_12_2850 Thermophiles and carbohydrate-active enzymes (CAZymes) in biofilm microbial consortia that decompose lignocellulosic plant litters at high temperatures
Liu_2022_Aquat.Toxicol_245_106118 Effects of short-term exposure to tralopyril on physiological indexes and endocrine function in turbot (Scophthalmus maximus)
Malafaia_2022_Aquat.Toxicol_245_106104 Toxicological impact of SARS-CoV-2 on the health of the neotropical fish, Poecilia reticulata
Omedes_2022_Environ.Res_210_112961 B-esterases characterisation in the digestive tract of the common octopus and the European cuttlefish and their in vitro responses to contaminants of environmental concern
Onder_2022_Neurotoxicol__ Butyrylcholinesterase in SH-SY5Y human neuroblastoma cells
Onikanni_2022_Biomed.Pharmacother_148_112730 Therapeutic efficacy of Clompanus pubescens leaves fractions via downregulation of neuronal cholinesterases\/Na(+)-K(+)ATPase\/IL-1 beta, and improving the neurocognitive and antioxidants status of streptozotocin-induced diabetic rats
Ozcelikay_2022_Chemosphere_296_133974 New analytical strategies Amplified with 2D carbon nanomaterials for electrochemical sensing of food pollutants in water and soils sources
Staykov_2022_J.Mol.Neurosci__ Neuromodulatory Mechanisms of a Memory Loss-Preventive Effect of Alpha-Lipoic Acid in an Experimental Rat Model of Dementia
Villarroel_2022_Insect.Biochem.Mol.Biol__103742 Genome sequencing of a predominant clonal lineage of the grain aphid Sitobion avenae
Wang_2022_J.Agric.Food.Chem_70_2520 Enantioselective Metabolic Mechanism and Metabolism Pathway of Pydiflumetofen in Rat Liver Microsomes: In Vitro and In Silico Study
Xiao_2022_3.Biotech_12_60 Isolation and acetylcholinesterase inhibitory activity of asterric acid derivatives produced by Talaromyces aurantiacus FL15, an endophytic fungus from Huperzia serrata
Youdim_2022_J.Neural.Transm.(Vienna)__ Site-activated multi target iron chelators with acetylcholinesterase (AChE) and monoamine oxidase (MAO) inhibitory activities for Alzheimer's disease therapy
Zhang_2022_Pest.Manag.Sci__ Toxicity, Horizontal Transfer, Physiological and Behavioral Effects of Cycloxaprid against Solenopsis invicta (Hymenoptera: Formicidae)
Zhu_2022_Gene_822_146340 A hypothesis-driven study to comprehensively investigate the association between genetic polymorphisms in EPHX2 gene and cardiovascular diseases: findings from the UK Biobank
Zia_2022_Bioorg.Chem_121_105658 Synthesis, structure and acetylcholinesterase inhibition activity of new diarylpyrazoles
Abobakr_2022_Insects_13_ Organophosphate Insecticides Resistance in Field Populations of House Flies, Musca domestica L.: Levels of Resistance and Acetylcholinesterase Activity
Ademosun_2022_Curr.Res.Food.Sci_5_366 Influence of Moringa (Moringa oleifera) enriched ice creams on rats' brain: Exploring the redox and cholinergic systems
Aksoy_2022_Turk.J.Pharm.Sci_19_76 Essential Oil Content, Antioxidative Characteristics and Enzyme Inhibitory Activity of Sideritis akmanii Aytac, Ekici & Donmez
Antika_2022_ACS.Chem.Neurosci_13_572 Strigolactone Analogs: Two New Potential Bioactiphores for Glioblastoma
Arora_2022_CNS.Neurol.Disord.Drug.Targets__ Neuroprotective Efficacy of Edaravone against Arsenic-Induced Behavioral and Neurochemical Deficits in Rats: Amelioration of Cholinergic and Mitochondrial Functions
Arya_2022_J.Fungi.(Basel)_8_ The Multifaceted Roles of Fungal Cutinases during Infection
Aykac_2022_Metab.Brain.Dis__ A multi-parameter evaluation of the neuroprotective and cognitive-enhancing effects of Origanum onites L. (Turkish Oregano) essential oil on scopolamine-induced amnestic rats
Bailey-Taylor_2022_Brain.Sci_12_ Gender Differences in Demographic and Pharmacological Factors in Patients Diagnosed with Late-Onset of Alzheimer's Disease
Barik_2022_Int.J.Anal.Chem_2022_6403090 Purification and Optimization of Extracellular Lipase from a Novel Strain Kocuria flava Y4
Bjedov_2022_J.Exp.Zool.A.Ecol.Integr.Physiol__ Blood biomarkers in white stork (Ciconia ciconia) nestlings show different responses in several areas of Croatia
Borges_2022_Toxicon__ Modulation of the cholinergic pathway induced by skin secretion of Phyllomedusa iheringii Boulenger, 1885 in a vertebrate model
Caratelli_2022_Biosens.Bioelectron_205_114119 A paper-based electrochemical device for the detection of pesticides in aerosol phase inspired by nature: A flower-like origami biosensor for precision agriculture
Chen_2022_J.Chem.Inf.Model__ Activation Mechanism of Strigolactone Receptors and Its Impact on Ligand Selectivity between Host and Parasitic Plants
Chen_2022_Biomedicines_10_ Vitisin A, a Resveratrol Tetramer, Improves Scopolamine-Induced Impaired Learning and Memory Functions in Amnesiac ICR Mice
Chu_2022_Antioxidants.(Basel)_11_ Comparison of Various Solvent Extracts and Major Bioactive Components from Unsalt-Fried and Salt-Fried Rhizomes of Anemarrhena asphodeloides for Antioxidant, Anti-alpha-Glucosidase, and Anti-Acetylcholinesterase Activities
Cortes_2022_Metabolites_12_ Phenolic Profile, Antioxidant and Enzyme Inhibition Properties of the Chilean Endemic Plant Ovidia pillopillo (Gay) Meissner (Thymelaeaceae)
Dorababu_2022_Eur.J.Pharmacol__174847 Promising heterocycle-based scaffolds in recent (2019-2021) anti-Alzheimer's drug design and discovery
Dragomanova_2022_Antioxidants.(Basel)_11_ Neuroprotective Effects of Myrtenal in an Experimental Model of Dementia Induced in Rats
Enespa_2022_Crit.Rev.Food.Sci.Nutr__1 Sources, purification, immobilization and industrial applications of microbial lipases: An overview
Fernandez-Galleguillos_2022_Metabolites_12_ Alkaloid Profiling, Anti-Enzymatic and Antiproliferative Activity of the Endemic Chilean Amaryllidaceae Phycella cyrtanthoides
Finlayson_2022_New.Phytol__ Branching's sweet spot: strigolactone signaling mediates sucrose effects on bud outgrowth
Garcia-Oliva_2022_Int.J.Mol.Sci_23_ Enzymatic Synthesis and Molecular Modelling Studies of Rhamnose Esters Using Lipase from Pseudomonas stutzeri
Gaudencio_2022_Mar.Drugs_20_ Predicting Antifouling Activity and Acetylcholinesterase Inhibition of Marine-Derived Compounds Using a Computer-Aided Drug Design Approach
Hua_2022_Molecules_27_ Rapid Screening of Lipase Inhibitors from Ophiopogonis Radix Using High-Performance Thin Layer Chromatography by Two Step Gradient Elution Combined with Bioautographic Method
Iorjiim_2022_Ann.Pharm.Fr__ Senescence and Oxidative Stress Toxicities Induced by Lamivudine and Tenofovir in Drosophila melanogaster
Ishola_2022_Drug.Metab.Pers.Ther__ Kolaviron ameliorates chronic unpredictable mild stress-induced anxiety and depression: involvement of the HPA axis, antioxidant defense system, cholinergic, and BDNF signaling
Kamli_2022_Plants.(Basel)_11_ Phytochemical Screening of Rosmarinus officinalis L. as a Potential Anticholinesterase and Antioxidant-Medicinal Plant for Cognitive Decline Disorders
Karunakaran_2022_Nat.Prod.Bioprospect_12_6 Novel insights on acetylcholinesterase inhibition by Convolvulus pluricaulis, scopolamine and their combination in zebrafish
Kashyap_2022_Curr.Drug.Res.Rev__ A review on structurally diversified synthesized molecules as monoacylglycerol lipase inhibitors and their therapeutic uses
Kim_2022_FEMS.Microbiol.Ecol__ Effect of strigolactones on recruitment of the rice root-associated microbiome
Klaus_2022_Brain.Commun_4_fcac018 Structural and functional brain alterations in patients with myasthenia gravis
Kohoutova_2022_J.Enzyme.Inhib.Med.Chem_37_760 Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides
Kondakala_2022_J.Biochem.Mol.Toxicol__e23028 Effect of high fat diet on the toxicokinetics and toxicodynamics of chlorpyrifos following acute exposure in male C57BL\/6J mice
Kopanska_2022_Int.J.Mol.Sci_23_2030 Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System
Kuo_2022_Chin.J.Physiol_65_1 Epoxyeicosatrienoic acids and soluble epoxide hydrolase in physiology and diseases of the central nervous system
Lai_2022_Biology.(Basel)_11_ Plant Terpenoids as the Promising Source of Cholinesterase Inhibitors for Anti-AD Therapy
Le_2022_Int.J.Biol.Macromol__ Dual functional roles of a novel bifunctional beta-lactamase\/esterase from Lactococcus garvieae
Liu_2022_J.Plant.Res__ Strigolactone is involved in nitric oxide-enhanced the salt resistance in tomato seedlings
Liu_2022_Front.Biosci.(Landmark.Ed)_27_71 Cucurbitacin B exerts neuroprotection in a murine Alzheimer's disease model by modulating oxidative stress, inflammation, and neurotransmitter levels
Long_2022_Chem.Biodivers__e202100925 Asperbenzophenone A and Versicolamide C, New Fungal Metabolites from the Soft Coral Derived Aspergillus sp. SCSIO 41036
Makarian_2022_J.Mol.Struct_1247_ Synthesis, kinetic evaluation and molecular docking studies of donepezil-based acetylcholinesterase inhibitors
Mlakic_2022_Bioorg.Chem_121_105701 Synthesis, photochemistry and computational study of novel 1,2,3-triazole heterostilbenes: Expressed biological activity of their electrocyclization photoproducts
Mone_2022_J.Clin.Hypertens.(Greenwich)__ Global cognitive function correlates with P-wave dispersion in frail hypertensive older adults
Nagata_2022_Expert.Opin.Pharmacother__1 Pharmacotherapeutic combinations for the treatment of Alzheimer's disease
Neckermann_2022_Toxins.(Basel)_14_ Efficacy of Fumonisin Esterase in Piglets as Animal Model for Fumonisin Detoxification in Humans: Pilot Study Comparing Intraoral to Intragastric Administration
Nosaka_2022_Molecules_27_ Striatal Cholinergic Signaling in Time and Space
Olabiyi_2022_Andrologia__e14404 Quercetin boosts nitric oxide levels and modulates the activities of arginase, acetylcholinesterase and adenosine deaminase in the corpus cavernosum of cyclosporine-treated rats
Petric_2022_Molecules_27_ The Removal of Time-Concentration Data Points from Progress Curves Improves the Determination of K(m): The Example of Paraoxonase 1
Rehman_2022_PeerJ_10_e12815 Knockdown of GmD53a confers strigolactones mediated rhizobia interaction and promotes nodulation in soybean
Sabnis_2022_ACS.Med.Chem.Lett_13_162 Novel Aminocyclobutanes as Monoacylglycerol Lipase Modulators
Santos_2022_Environ.Toxicol.Pharmacol__103835 Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae
Schnitzler_2022_Micromachines.(Basel)_13_ Acetylcholinesterase Activity Influenced by Lipid Membrane Area and Surface Acoustic Waves
Shen_2022_Plants.(Basel)_11_ Plant GDSL Esterases\/Lipases: Evolutionary, Physiological and Molecular Functions in Plant Development
Singh_2022_Cell.Tissue.Res__ Guanabenz mitigates the neuropathological alterations and cell death in Alzheimer's disease
Singh_2022_ACS.Chem.Neurosci__ Donepezil-Inspired Multitargeting Indanone Derivatives as Effective Anti-Alzheimer's Agents
Singhania_2022_Chem.Sci_13_1440 Lipase-catalyzed esterification in water enabled by nanomicelles. Applications to 1-pot multi-step sequences
Song_2022_J.Clin.Invest_132_ Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells
Sowa_2022_J.Agric.Food.Chem__ Replacement of Pregastric Lipases in Cheese Production: Identification and Heterologous Expression of a Lipase from Pleurotus citrinopileatus
Srikanta_2022_New.Phytol__ Plant volatiles as regulators of hormone homeostasis
Taheri_2022_BMC.Chem_16_7 Synthesis, in vitro biological evaluation and molecular modelling of new 2-chloro-3-hydrazinopyrazine derivatives as potent acetylcholinesterase inhibitors on PC12 cells
Tanaka_2022_J.Atheroscler.Thromb__ Anti-GPIHBP1 Antibody-Positive Autoimmune Hyperchylomicronemia and Immune Thrombocytopenia
Tezcan_2022_J.Biochem.Mol.Toxicol__e23001 Benzimidazolium salts bearing the trifluoromethyl group as organofluorine compounds: Synthesis, characterization, crystal structure, in silico study, and inhibitory profiles against acetylcholinesterase and alpha-glycosidase
Thangwong_2022_Biochem.Pharmacol_198_114980 Melatonin improves cognitive function by suppressing endoplasmic reticulum stress and promoting synaptic plasticity during chronic cerebral hypoperfusion in rats
Uddin_2022_Fitoterapia__105164 Insights into the leaves of Ceriscoides campanulata: Natural proanthocyanidins alleviate diabetes, inflammation, and esophageal squamous cell cancer via in vitro and in silico models
Vogt_2022_Pharmacol.Biochem.Behav__173357 QCTA-1, a quinoline derivative, ameliorates pentylenetetrazole-induced kindling and memory comorbidity in mice: Involvement of antioxidant system of brain
Wang_2022_Fish.Shellfish.Immunol_123_1 Acute effects of antimony exposure on adult zebrafish (Danio rerio): From an oxidative stress and intestinal microbiota perspective
Wright_2022_Antioxidants.(Basel)_11_ Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial
Wu_2022_Nutrients_14_ The Composition and Anti-Aging Activities of Polyphenol Extract from Phyllanthus emblica L. Fruit
Yakan_2022_J.Biochem.Mol.Toxicol__e23018 Potential thiosemicarbazone-based enzyme inhibitors: Assessment of antiproliferative activity, metabolic enzyme inhibition properties, and molecular docking calculations
Yang_2022_Eur.J.Med.Chem_233_114216 A multifunctional anti-AD approach: Design, synthesis, X-ray crystal structure, biological evaluation and molecular docking of chrysin derivatives
Zhang_2022_J.Plant.Physiol_270_153640 GR24-mediated enhancement of salt tolerance and roles of H(2)O(2) and Ca(2+) in regulating this enhancement in cucumber
Zhou_2022_BMC.Plant.Biol_22_30 Physiological mechanism of strigolactone enhancing tolerance to low light stress in cucumber seedlings
Zhu_2022_Alzheimers.Dement__ Racial\/ethnic disparities in initiation and persistent use of anti-dementia medications
Wei_2022_ACS.Catal_12_3382 Mechanism-Based Design of Efficient PET Hydrolases
Aggarwal_2022_Physiol.Behav__113767 Neurobehavioral and neurobiochemical effect of atomoxetine and N-acetylcysteine in streptozotocin diabetes induced endothelial dysfunction and related dementia
Al-Amin_2022_Adv.Pharmacol.Pharm.Sci_2022_8305271 Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress
Alzarea_2022_Front.Pharmacol_13_810052 Butin Attenuates Arthritis in Complete Freund's Adjuvant-Treated Arthritic Rats: Possibly Mediated by Its Antioxidant and Anti-Inflammatory Actions
Anupama_2022_Neurotoxicol__ Jatamansinol from Nardostachys jatamansi (D.Don) DC. Protects Abeta(42)-induced Neurotoxicity in Alzheimer's Disease Drosophila Model
Atef_2022_Neurochem.Res__ Mechanistic Insights into Ameliorating Effect of Geraniol on D-Galactose Induced Memory Impairment in Rats
Aydin_2022_Phytochem.Anal__ A new specific method for isolation of tomentosin with a high yield from Inula viscosa (L.) and determination of its bioactivities
Bashir_2022_ACS.Omega_7_6472 Nanonization of Magnoflorine-Encapsulated Novel Chitosan-Collagen Nanocapsules for Neurodegenerative Diseases: In Vitro Evaluation
Capece_2022_Mol.Cell.Oncol_9_2024051 Rewired lipid metabolism as an actionable vulnerability of aggressive colorectal carcinoma
Checler_2022_Neural.Regen.Res_17_2215 Aminopeptidase A and dipeptidyl peptidase 4: a pathogenic duo in Alzheimer's disease?
Chen_2022_Drug.Des.Devel.Ther_16_509 alpha-Mangostin Treats Early-Stage Adjuvant-Induced Arthritis of Rat by Regulating the CAP-SIRT1 Pathway in Macrophages
da Silva_2022_Mar.Pollut.Bull_177_113469 Non-destructive biomarkers can reveal effects of the association of microplastics and pharmaceuticals or personal care products
Dastan_2022_J.Mol.Model_28_86 An arginine-rich peptide inhibits AChE: template-based design, molecular modeling, synthesis, and biological evaluation
Ding_2022_Crit.Rev.Anal.Chem__1 Electrochemical (Bio)Sensors for the Detection of Organophosphorus Pesticides Based on Nanomaterial-Modified Electrodes: A Review
Du_2022_J.Neurol__ Individualized regimen of low-dose rituximab monotherapy for new-onset AChR-positive generalized myasthenia gravis
El-Feky_2022_Biomarkers__1 Salvia hispanica L. seeds extract alleviate encephalopathy in streptozotocin-induced diabetes in rats: Role of oxidative stress, neurotransmitters, DNA and histological indices
Falidas_2022_In.Vivo_36_738 Secretory Phospholipase A2 Digital Expression Analysis in Colon Adenocarcinoma
Faria_2022_J.Hazard.Mater_431_128563 Environmental levels of carbaryl impair zebrafish larvae behaviour: The potential role of ADRA2B and HTR2B
Faro_2022_Pestic.Biochem.Physiol_182_105035 Protective effects of antioxidants on striatal dopamine release induced by organophosphorus pesticides
Ferreira_2022_Neurotox.Res__ Quinolinic Acid Impairs Redox Homeostasis, Bioenergetic, and Cell Signaling in Rat Striatum Slices: Prevention by Coenzyme Q(10)
Frouni_2022_Prog.Brain.Res_269_373 Cognition and serotonin in Parkinson's disease
Hamdi_2022_Pestic.Biochem.Physiol_182_105034 Subchronic exposure to Epoxiconazole induced-heart damage in male Wistar rats
He_2022_Nucl.Med.Biol_108-109_24 Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold
Isik_2022_SAR.QSAR.Environ.Res__1 Synthesis and molecular modelling of thiadizole based hydrazone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitory activities
Lazarevic_2022_Front.Physiol_13_842314 Assessment of Sex-Specific Toxicity and Physiological Responses to Thymol in a Common Bean Pest Acanthoscelides obtectus Say
Li_2022_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_274_121097 Redox-regulated synthesis of fluorescent polydopamine nanoparticles for detection of butyrylcholinesterase activity
Li_2022_BMC.Genomics_23_185 Characterization of pectin methylesterase gene family and its possible role in juice sac granulation in navel orange (Citrus sinensis Osbeck)
Liu_2022_Sci.Rep_12_3531 Association between long-term usage of acetylcholinesterase inhibitors and lung cancer in the elderly: a nationwide cohort study
Pereira_2022_Glycoconj.J__ Protective Effects of a synthetic glycosaminoglycan mimetic (OTR4132) in a rat immunotoxic lesion model of septohippocampal cholinergic degeneration
Perez-Iglesias_2022_Environ.Sci.Pollut.Res.Int__ Comprehensive evaluation of the toxicity of the flame retardant (decabromodiphenyl ether) in a bioindicator fish (Gambusia affinis)
Piau_2022_Genet.Mol.Biol_45_e20210307 In the screening of alternative insecticides to control Aedes aegytpti larvae 2-methylanthraquinone showed no genotoxicity and low toxicity to zebrafish (Danio rerio)
Pretre_2022_Ann.Allergy.Asthma.Immunol__ Dipeptidyl peptidase IV of the Vespa velutina nigrithorax venom is recognized as a relevant allergen
Qi_2022_Anal.Chem__ Multifunctional Fluorescent Probe for Simultaneously Detecting Microviscosity, Micropolarity, and Carboxylesterases and Its Application in Bioimaging
Rafeeinia_2022_J.Investig.Med__ Organochlorine pesticides, oxidative stress biomarkers, and leukemia: a case-control study
Rehman_2022_PLoS.One_17_e0264074 The Insight of In Silico and In Vitro evaluation of Beta vulgaris phytochemicals against Alzheimer's disease targeting acetylcholinesterase
Saeedi_2022_Recent.Pat.Biotechnol__ Challenges and approaches of drugs such as Memantine, Donepezil, Rivastigmine and Aducanumab in the treatment, control and management of Alzheimer's disease
Singh_2022_Chembiochem__ Carbonate-Based Fluorescent Chemical Tool for Uncovering Carboxylesterase 1 (CES1) Activity Variations in Live Cells
Tang_2022_3.Biotech_12_84 A review of physiological resistance to insecticide stress in Nilaparvata lugens
Thomsen_2022_N.Biotechnol__ Influence of substrate crystallinity and glass transition temperature on enzymatic degradation of polyethylene terephthalate (PET)
Tunali_2022_J.Biochem.Mol.Toxicol__e22991 Protective effects of N(1)-2,4-dihydroxybenzylidene-N(4)-2-hydroxybenzylidene-S-methyl-thiosemicarbazidato-oxovanadium (IV) on oxidative brain injury in streptozotocin-induced diabetic rats
Uthra_2022_Toxicol.Res.(Camb)_11_215 Protective efficacy of rutin against acrylamide-induced oxidative stress, biochemical alterations and histopathological lesions in rats
Wang_2022_PLoS.Negl.Trop.Dis_16_e0010208 A symbiotic gut bacterium enhances Aedes albopictus resistance to insecticide
Wang_2022_Biol.Trace.Elem.Res__ The Relationship Between Zinc Deficiency and Hepatocellular Carcinoma Associated with Hepatitis B Liver Cirrhosis: A 10-year Follow-up Study
Wu_2022_Proteomics__e2100028 Effects of ABCG1 knockout on proteomic composition of HDL in mice on a chow diet and a high-fat diet
Xu_2022_Food.Chem_382_132106 Analysis of the binding selectivity and inhibiting mechanism of chlorogenic acid isomers and their interaction with grass carp endogenous lipase using multi-spectroscopic, inhibition kinetics and modeling methods
Zhang_2022_Talanta_243_123284 Rapid screening for acetylcholinesterase inhibitors in Selaginella doederleinii Hieron by using functionalized magnetic Fe(3)O(4) nanoparticles
Zhang_2022_Eur.Rev.Med.Pharmacol.Sci_26_1183 Pharmacokinetics of HupA-PLGA-NPs of different sizes in the mouse blood and brain determined by LC-MS\/MS
Zhao_2022_Anal.Biochem__114628 A stable enzyme sensor via embedding enzymes into zeolitic imidazolate frameworks for pesticide determination
Adedara_2022_Sci.Rep_12_3922 An assessment of the rescue action of resveratrol in parkin loss of function-induced oxidative stress in Drosophila melanogaster
Baek_2022_Int.J.Environ.Res.Public.Health_19_ Efficient Production of Naringin Acetate with Different Acyl Donors via Enzymatic Transesterification by Lipases
Baronio_2022_Mol.Genet.Metab.Rep_30_100833 Diagnosis, treatment, and follow-up of a case of Wolman disease with hemophagocytic lymphohistiocytosis
Capo_2022_Environ.Res_211_113063 Quantification of differential tissue biomarker responses to microplastic ingestion and plasticizer bioaccumulation in aquaculture reared sea bream Sparus aurata
Chahouri_2022_Chemosphere__134149 Integration assay of bacteriological risks in marine environment using salmonella spp and multimarker response in the bivalve Donax trunculus: Novel biomonitoring approach
Chen_2022_J.Zhejiang.Univ.Sci.B_23_230 A new benzaldehyde from the coral-derived fungus Aspergillus terreus C23-3 and its anti-inflammatory effects via suppression of MAPK signaling pathway in RAW264.7 cells
G_2022_PeerJ_10_e13040 Abubidentin A, New Oleanane-type Triterpene Ester from Abutilon bidentatum and its antioxidant, cholinesterase and antimicrobial activities
Garay-Garcia_2022_J.Clin.Lipidol__ Severe hypertriglyceridemia secondary to splice-site and missense variants in LMF1 in three patients from Ecuador
Georgieva_2022_Heliyon_8_e09069 Biomarkers for pollution in caged mussels from three reservoirs in Bulgaria: A pilot study
Giacobini_2022_Brain_145_2250 Reimagining cholinergic therapy for Alzheimer's disease
Goeritzer_2022_Cells_11_ Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo
Gomaa_2022_Eur.J.Pharmacol__174873 Advancing combination treatment with cilostazol and caffeine for Alzheimer's disease in high fat-high fructose-STZ induced model of amnesia
Guimaraes_2022_Am.J.Physiol.Cell.Physiol__ Neuronal cholinergic signaling constrains norepinephrine activity in the heart
Ibi_2022_J.Lipid.Res__100193 Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses
Kikukawa_2022_J.Biosci.Bioeng__ Recent trends in the field of lipid engineering
Kowalczyk_2022_Materials.(Basel)_15_ Promiscuous Lipase-Catalyzed Markovnikov Addition of H-Phosphites to Vinyl Esters for the Synthesis of Cytotoxic alpha-Acyloxy Phosphonate Derivatives
Kwon_2022_Front.Endocrinol.(Lausanne)_13_824269 The Effect of Orlistat on Sterol Metabolism in Obese Patients
Li_2022_Front.Physiol_13_826314 The Molecular Brakes of Adipose Tissue Lipolysis
Lipinski_2022_Int.J.Mol.Sci_23_ Fentanyl Structure as a Scaffold for Opioid\/Non-Opioid Multitarget Analgesics
Melchert_2022_Chem.Biol.Interact__109883 In vitro inhibition of carboxylesterase 1 by Kava (Piper methysticum) Kavalactones
Mervic_2022_Plants.(Basel)_11_ Comparative Antioxidant, Anti-Acetylcholinesterase and Anti-alpha-Glucosidase Activities of Mediterranean Salvia Species
Nasello_2022_Environ.Sci.Pollut.Res.Int__ Thermal paper as a potential source of bisphenol A for humans and the environment: migration and ecotoxicological impact
Palanichamy_2022_Probiotics.Antimicrob.Proteins__ Haloalkaline Lipase from Bacillus flexus PU2 Efficiently Inhibits Biofilm Formation of Aquatic Pathogen Vibrio parahaemolyticus
Patti_2022_Int.J.Mol.Sci_23_ Stereoselective Promiscuous Reactions Catalyzed by Lipases
Perrone_2022_J.Transl.Med_20_107 LPL, FNDC5 and PPARgamma gene polymorphisms related to body composition parameters and lipid metabolic profile in adolescents from Southern Italy
Qin_2022_Front.Nutr_9_844195 Discovery and Characterization of the Naturally Occurring Inhibitors Against Human Pancreatic Lipase in Ampelopsis grossedentata
Rasool_2022_Molecules_27_ In Vivo Assessment of the Ameliorative Impact of Some Medicinal Plant Extracts on Lipopolysaccharide-Induced Multiple Sclerosis in Wistar Rats
Shang_2022_Neoplasma__ Endothelial lipase promotes acute myeloid leukemia progression through metabolic reprogramming
Song_2022_Int.J.Mol.Sci_23_ Thermally Stable and Reusable Ceramic Encapsulated and Cross-Linked CalB Enzyme Particles for Rapid Hydrolysis and Esterification
Truzzi_2022_Molecules_27_ Characterization and Valorization of the Agricultural Waste Obtained from Lavandula Steam Distillation for Its Reuse in the Food and Pharmaceutical Fields
Ugwu_2022_Brain.Res.Bull__ Putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin
Wang_2022_J.Anim.Physiol.Anim.Nutr.(Berl)__ Correlation of lipoprotein lipase gene polymorphism and mRNA expression with intramuscular fat content in Baicheng-Oil chicken
Wang_2022_Carbohydr.Polym_284_119193 Lipase induced highly hydrophobic nanofibrillated cellulose film for strain sensor application
Xin_2022_Front.Pharmacol_13_729605 Pantao Pill Improves the Learning and Memory Abilities of APP\/PS1 Mice by Multiple Mechanisms
Xu_2022_Ann.Transl.Med_10_169 Analysis of transcript-wide profile regulated by microsatellite instability of colorectal cancer
Xue_2022_Front.Bioeng.Biotechnol_10_850890 Enhancing the Catalytic Performance of Candida antarctica Lipase B by Chemical Modification With Alkylated Betaine Ionic Liquids
Yamada_2022_J.Lipid.Res__100194 Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy
Yu_2022_Biotechnol.Appl.Biochem__ Lipase-catalyzed hydrazine insertion for the synthesis of N'-alkyl benzohydrazides
Zengin_2022_Molecules_27_ Chemical Composition, Biological Activities and In Silico Analysis of Essential Oils of Three Endemic Prangos Species from Turkey
Zengin_2022_Chem.Biodivers__ A comparative study of chemical profiling and biological effects of Doronicum orientale extracts
Zhang_2022_Plants.(Basel)_11_ Untargeted Phenolic Profiling and Functional Insights of the Aerial Parts and Bulbs of Drimia maritima (L.) Stearn
Zhao_2022_Org.Biomol.Chem__ Unprecedented diterpenoid dimers with soluble epoxide hydrolase inhibitory effect from Euphorbia fischeriana
Zhu_2022_J.Environ.Sci.Health.B__1 Detecting the combined toxicity of 18 binary and 24 ternary pesticide combinations to carboxylesterase based on fluorescence probe technology
zupanic_2022_Acta.Clin.Croat_60_496 Treatment of myasthenia gravis patients with covid-19: review of the literature
Abdalla_2022_Inflammopharmacology__ Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporomandibular joint
Ademiluyi_2022_Drug.Chem.Toxicol__1 Evaluating Water bitter leaf (Struchium sparganophora) and Scent Leaf (Ocimum gratissimum) extracts as sources of nutraceuticals against manganese-induced toxicity in fruit fly model
Akinade_2022_Sci.Rep_12_4594 Protective capacity of carotenoid trans-astaxanthin in rotenone-induced toxicity in Drosophila melanogaster
Arya_2022_Mol.Biol.Rep__ Environment dependent expression of mycobacterium hormone sensitive lipases: expression pattern under ex-vivo and individual in-vitro stress conditions in M. tuberculosis H37Ra
Aryal_2022_Evid.Based.Complement.Alternat.Med_2022_7299778 Potential Therapeutic Applications of Plant-Derived Alkaloids against Inflammatory and Neurodegenerative Diseases
Bailey_2022_BMC.Genomics_23_198 A near-chromosome level genome assembly of the European hoverfly, Sphaerophoria rueppellii (Diptera: Syrphidae), provides comparative insights into insecticide resistance-related gene family evolution
Balasubramaniam_2022_J.Lipid.Res__100198 An anti-ANGPTL3\/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif
Bergmann_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2120691119 sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury
Byun_2022_Sci.Rep_12_4451 Analysis of treatment pattern of anti-dementia medications in newly diagnosed Alzheimer's dementia using OMOP CDM
Cinque_2022_Nutrients_14_ Interaction between Lifestyle Changes and PNPLA3 Genotype in NAFLD Patients during the COVID-19 Lockdown
Correira_2022_Langmuir_38_3501 Formation and Characterization of a Stable Monolayer of Active Acetylcholinesterase on Planar Gold
de Oliveira_2022_J.Neuropsychiatry.Clin.Neurosci__appineuropsych21060160 APOE sigma4 Carrier Status as Mediator of Effects of Psychotropic Drugs on Clinical Changes in Patients With Alzheimer's Disease
Gimeno-Perez_2022_ChemSusChem__ A coupled ketoreductase-diaphorase assay for the detection of polyethylene terephthalate-hydrolyzing activity
Hue_2022_Nat.Prod.Res__1 Glycoside constituents from Miliusa sinensis leaves and their anti-inflammatory and acetylcholine protective effects
Ibrahim_2022_Acta.Trop_230_106405 Immunotoxical, neurotoxical, histopathological and immunohistopathological alterations of Nerium oleander and Tecoma stans methanolic extract on Biomphalaria alexandrina snails
Isaac_2022_J.Natl.Med.Assoc__ Tolerability of memantine monotherapy versus adding memantine as combination therapy
Jaiswal_2022_Bioorg.Med.Chem_60_116698 Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones
Jusril_2022_Evid.Based.Complement.Alternat.Med_2022_3483511 Development and Optimization of Nanoemulsion from Ethanolic Extract of Centella asiatica (NanoSECA) Using D-Optimal Mixture Design to Improve Blood-Brain Barrier Permeability
Kambayashi_2022_J.Pharmacol.Sci_148_343 Analysis of clinically-reported, memantine-induced cardiovascular adverse responses using the halothane-anesthetized dogs: Reverse translational study
Khedr_2022_J.Biochem.Mol.Toxicol__e23040 New insights into arsenic, lead, and iron neurotoxicity: Activation of MAPK signaling pathway and oxidative stress
Lackmann_2022_Environ.Int_163_107190 Two types of microplastics (polystyrene-HBCD and car tire abrasion) affect oxidative stress-related biomarkers in earthworm Eisenia andrei in a time-dependent manner
Lesmana_2022_Rep.Biochem.Mol.Biol_10_589 Organophosphate Resistance in Aedes aegypti: Study from Dengue Hemorrhagic Fever Endemic Subdistrict in Riau, Indonesia
Li_2022_Methods.Mol.Biol_2474_47 Acetylcholinesterase Inhibition Assays for High-Throughput Screening
Li_2022_Front.Genet_13_831133 Case Report: Next-Generation Sequencing Identified a Novel Pair of Compound-Heterozygous Mutations of LPL Gene Causing Lipoprotein Lipase Deficiency
Liu_2022_J.Biotechnol__ Enhanced biodegradation activity towards poly(ethyl acrylate) and poly(vinyl acetate) by anchor peptide assistant targeting
MK_2022_An.Acad.Bras.Cienc_94_e20210540 Extracellular hydrolytic enzymes produced by yeasts from Antarctic lichens
Orozco-Hernandez_2022_Neurotoxicol__ Fluoxetine-induced neurotoxicity at environmentally relevant concentrations in adult zebrafish Danio rerio
Parlak_2022_Toxicol.Mech.Methods__1 Hematotoxic, oxidative and genotoxic damage in rainbow trout (Oncorhynchus mykiss) after exposure to 3-benzoylpyridine
Patel_2022_Drug.Dev.Res__ Repurposing of digoxin in pain and inflammation: An evidence-based study
Pompermaier_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_257_109328 Impaired initial development and behavior in zebrafish exposed to environmentally relevant concentrations of widely used pesticides
Puttagunta_2022_Cureus_14_e22125 Tiny Toes to Tau Tangles: Down's Syndrome and Its Association With Alzheimer's Disease
Sahin_2022_Chem.Biodivers__ Enzyme Inhibition Properties and Molecular Docking Studies of 4-Sulfonate Containing Aryl alpha-Hydroxyphosphonates Based Hybrid Molecules
Saleem_2022_Chem.Biodivers__ Chemodiversity, biological activities and molecular docking studies of Leptadenia pyrotechnica (Forssk.) Decne: A comprehensive approach to validate its medicinal use
Sanchez-Barrionuevo_2022_Biochimie__ Identification of an acetyl esterase in the supernatant of the environmental strain Bacillus sp. HR21-6
Santos_2022_Environ.Pollut__119166 The role of nanoplastics on the toxicity of the herbicide phenmedipham, using Danio rerio embryos as model organisms
Skoug_2022_J.Lipid.Res__100195 Hormone-sensitive lipase is localized at synapses and is necessary for normal memory functioning in mice
Sun_2022_Eur.J.Med.Chem_234_114210 Development of 5-hydroxyl-1-azabenzanthrone derivatives as dual binding site and selective acetylcholinesterase inhibitors
Takano_2022_Int.J.Colorectal.Dis__ The impact of low serum cholinesterase levels on survival in patients with colorectal cancer
Tanase_2022_J.Pharmacol.Sci_148_364 Effects of galantamine on social interaction impairments in cholecystokinin receptor-2 overexpression mice
Tang_2022_Environ.Sci.Technol__ Circadian Rhythm and Neurotransmitters Are Potential Pathways through Which Ocean Acidification and Warming Affect the Metabolism of Thick-Shell Mussels
Teng_2022_Environ.Sci.Pollut.Res.Int__ Combined toxicity of chlorpyrifos, abamectin, imidacloprid, and acetamiprid on earthworms (Eisenia fetida)
Wang_2022_Front.Physiol_13_818531 A New Method to Address the Importance of Detoxified Enzyme in Insecticide Resistance - Meta-Analysis
Wang_2022_Anal.Chem__ Esterase-Activated Precipitating Strategy to Achieve Highly Specific Detection and Long-Term Imaging of Calcium Ions by Aggregation-Induced Phosphorescence Probe
Wei_2022_Bioelectrochemistry_145_108094 A novel pomegranate-inspired bifunctional electrode materials design for acetylcholinesterase biosensor and methanol oxidation reaction
Xu_2022_Plant.Physiol__ A maize triacylglycerol lipase inhibits sugarcane mosaic virus infection
Zhang_2022_Front.Bioeng.Biotechnol_10_824300 Gram-Scale Synthesis of (R)-P-Chlorophenyl-1,2-Ethanediol at High Concentration by a Pair of Epoxide Hydrolases
Zhao_2022_Arch.Toxicol__ Inter-individual variation in chlorpyrifos toxicokinetics characterized by physiologically based kinetic (PBK) and Monte Carlo simulation comparing human liver microsome and Supersome() cytochromes P450 (CYP)-specific kinetic data as model input
Akbarian_2022_Inflammopharmacology__ Amelioration of oxidative stress, cholinergic dysfunction, and neuroinflammation in scopolamine-induced amnesic rats fed with pomegranate seed
Amat_2022_Brain.Behav.Evol__ Neurogenetic heterochrony in chick, lizard and rat mapped with wholemount AChE and the prosomeric model
Bibi_2022_Molecules_27_ Towards the Pharmacological Validation and Phytochemical Profiling of the Decoction and Maceration of Bruguiera gymnorhiza (L.) Lam.-A Traditionally Used Medicinal Halophyte
Cao_2022_Toxicol.Lett_361_1 Neuroligin-1 plays an important role in methamphetamine-induced hippocampal synaptic plasticity
Changlek_2022_Foods_11_ Curcumin Suppresses Lead-Induced Inflammation and Memory Loss in Mouse Model and In Silico Molecular Docking
Chen_2022_Metab.Brain.Dis__ Learning and memory impairment induced by 1,4-butanediol is regulated by ERK1\/2-CREB-BDNF signaling pathways in PC12 cells
Chen_2022_J.Mater.Chem.B__ Construction of a copper nanocluster\/MnO(2) nanosheet-based fluorescent platform for butyrylcholinesterase activity detection and anti-Alzheimer's drug screening
Cheng_2022_J.Agric.Food.Chem__ Assessing Dietary Pesticide Intake and Potential Health Effects: The Application of Global Metabolomics Analysis
Chu_2022_Nutrients_14_ Higher Serum DHA and Slower Cognitive Decline in Patients with Alzheimer's Disease: Two-Year Follow-Up
da Silva_2022_Molecules_27_ Phytochemicals of Avocado Residues as Potential Acetylcholinesterase Inhibitors, Antioxidants, and Neuroprotective Agents
de Souza_2022_Curr.Comput.Aided.Drug.Des__ Design of multitarget natural products analogs with potential anti-Alzheimer activity
Delogu_2022_Pharmaceuticals.(Basel)_15_ Structural Insight of New Butyrylcholinesterase Inhibitors Based on Benzylbenzofuran Scaffold
Dey_2022_Toxicol.Mech.Methods__1 Chronic oral exposure of aluminum chloride in rat modulates molecular and functional neurotoxic markers relevant to Alzheimer's disease
El-Tamalawy_2022_Front.Pharmacol_13_855764 Efficacy and Safety of Neostigmine Adjunctive Therapy in Patients With Sepsis or Septic Shock: A Randomized Controlled Trial
Garcia-Alberca_2022_Clin.Drug.Investig__ Benefits of Treatment with Ginkgo Biloba Extract EGb 761 Alone or Combined with Acetylcholinesterase Inhibitors in Vascular Dementia
George_2022_Int.J.Mol.Sci_23_ Structural Modifications on Chalcone Framework for Developing New Class of Cholinesterase Inhibitors
Gupta_2022_Ann.Indian.Acad.Neurol_25_100 PON1 (Paraoxonase 1) Q192R Gene Polymorphism in Ischemic Stroke among North Indian Population
He_2022_J.Hazard.Mater_432_128699 Potentially tunable ratiometric electrochemiluminescence sensing based on conjugated polymer nanoparticle for organophosphorus pesticides detection
Hetrick_2022_Methods.Enzymol_664_199 Assessing and utilizing esterase specificity in antimicrobial prodrug development
Hu_2022_Microorganisms_10_ Phthalate Esters Metabolic Strain Gordonia sp. GZ-YC7, a Potential Soil Degrader for High Concentration Di-(2-ethylhexyl) Phthalate
Kanti_2022_JCI.Insight__ Adipose triglyceride lipase mediated lipid catabolism is essential for bronchiolar regeneration
Leineweber_2022_J.Zoo.Wildl.Med_53_187 Comparison of clinical chemistry analytes in greater flamingos (Phoenicopterus roseus) and ameicn flamingos (Phoenicopterus ruber) in a zoo in europe
Li_2022_J.Hazard.Mater_432_128660 Ratiometric fluorescent hydrogel for point-of-care monitoring of organophosphorus pesticide degradation
Martinelli_2022_Nutrients_14_ Obesity-Related Brain Cholinergic System Impairment in High-Fat-Diet-Fed Rats
McGregor_2022_Methods.Enzymol_664_103 Detecting and identifying glycoside hydrolases using cyclophellitol-derived activity-based probes
Menden_2022_Sci.Rep_12_4797 Exogenous lipase administration alters gut microbiota composition and ameliorates Alzheimer's disease-like pathology in APP\/PS1 mice
Nematollahi_2022_Environ.Sci.Pollut.Res.Int__ Diazinon reduction in food products: a comprehensive review of conventional and emerging processing methods
Nguyen_2022_Micromachines.(Basel)_13_ Simple and Label-Free Detection of Carboxylesterase and Its Inhibitors Using a Liquid Crystal Droplet Sensing Platform
Olabiyi_2022_Andrologia__e14424 Diet, herbs and erectile function: A good friendship!
Peng_2022_Mar.Drugs_20_ Butenolides from the Coral-Derived Fungus Aspergillius terreus SCSIO41404
Qian_2022_Chem.Biodivers__e202200064 Baoshanmycin and a New Furanone Derivative from a Soil-Derived Actinomycete, Amycolatopsis sp. YNNP 00208
Rees_2022_Nat.Chem.Biol__ Systematic identification of biomarker-driven drug combinations to overcome resistance
Refaay_2022_Plants.(Basel)_11_ Growth Optimization and Secondary Metabolites Evaluation of Anabaena variabilis for Acetylcholinesterase Inhibition Activity
Shao_2022_Molecules_27_ Diversified Chaetoglobosins from the Marine-Derived Fungus Emericellopsis sp. SCSIO41202
Sieniawska_2022_Molecules_27_ Phytochemical Insights into Ficus sur Extracts and Their Biological Activity
Slavova_2022_Molecules_27_ Phytochemical Constituents and Pharmacological Potential of Tamus communis Rhizomes
Soong_2022_Bioengineering.(Basel)_9_ Recent Advances in Biological Recycling of Polyethylene Terephthalate (PET) Plastic Wastes
Sun_2022_Folia.Morphol.(Warsz)__ Propofol protects rats against intra-cerebroventricular Streptozotocin-induced cognitive dysfunction and neuronal damage
Tsagkaris_2022_Anal.Methods__ A critical comparison between an ultra-high-performance liquid chromatography triple quadrupole mass spectrometry (UHPLC-QqQ-MS) method and an enzyme assay for anti-cholinesterase pesticide residue detection in cereal matrices
Tundis_2022_Plants.(Basel)_11_ An Insight into Salvia haematodes L. (Lamiaceae) Bioactive Extracts Obtained by Traditional and Green Extraction Procedures
Wang_2022_Int.J.Mol.Sci_23_ Two Triacylglycerol Lipases Are Negative Regulators of Chilling Stress Tolerance in Arabidopsis
Wu_2022_Bioorg.Chem_122_105760 Design, synthesis and evaluation of novel scutellarin and scutellarein-N,N-bis-substituted carbamate-l-amino acid derivatives as potential multifunctional therapeutics for Alzheimer's disease
Xi_2022_Biomed.Environ.Sci_35_206 The Use of Lipoprotein-Associated Phospholipase A2 in a Chinese Population to Predict Cardiovascular Events
Xiao_2022_J.Fungi.(Basel)_8_ Polyketide Derivatives from the Endophytic Fungus Phaeosphaeria sp. LF5 Isolated from Huperzia serrata and Their Acetylcholinesterase Inhibitory Activities
Xu_2022_Mar.Drugs_20_ Rapid Mining of Novel alpha-Glucosidase and Lipase Inhibitors from Streptomyces sp. HO1518 Using UPLC-QTOF-MS\/MS
Youssef_2022_J.Food.Biochem__e14164 Antidepressant-like effects of aqueous extracts of miswak (Salvadora persica) and date palm (Phoenix dactylifera) on depression-like behaviors using CUMS model in male rats
Yu_2022_Molecules_27_2013 Bioactivity-Guided Separation of Anti-Cholinesterase Alkaloids from Uncaria rhynchophlly (Miq.) Miq. Ex Havil Based on HSCCC Coupled with Molecular Docking
Zhang_2022_Int.J.Mol.Sci_23_3361 Long-Term Effect of Porcine Brain Enzyme Hydrolysate Intake on Scopolamine-Induced Memory Impairment in Rats
Zhu_2022_Biochem.Biophys.Res.Commun_606_121 Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats
Zotta_2022_Microorganisms_10_ Selection of Lactiplantibacillus Strains for the Production of Fermented Table Olives
Alkharsah_2022_PLoS.One_17_e0266603 Low levels of soluble DPP4 among Saudis may have constituted a risk factor for MERS endemicity
Andre_2022_J.Sep.Sci__ Development of nano Bio LC columns for the search of acethylcholinesterase molecular targets
Argueta_2022_CNS.Drugs__ Role of Pharmacogenomics in Individualizing Treatment for Alzheimer's Disease
Bektasevic_2022_Chem.Biodivers__ Polyphenol Composition, Anticholinesterase and Antioxidant Potential of the Extracts of Clinopodium vulgare L
Benchaabane_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_257_109334 Multibiomarker responses after exposure to a sublethal concentration of thiamethoxam in the African honeybee (Apis mellifera intermissa)
Bezerra_2022_Environ.Toxicol.Pharmacol__103862 Can Lemna minor mitigate the effects of cadmium and nickel exposure in a Neotropical fish?
Bolukbasi_2022_Food.Chem.Toxicol_163_112994 A novel paraoxon imprinted electrochemical sensor based on MoS(2)NPs@MWCNTs and its application to tap water samples
Chavez-Guevara_2022_Eur.J.Appl.Physiol__ Biomarkers and genetic polymorphisms associated with maximal fat oxidation during physical exercise: implications for metabolic health and sports performance
Chen_2022_Food.Funct__ Carnosic acid ameliorated Abeta-mediated (amyloid-beta peptide) toxicity, cholinergic dysfunction and mitochondrial defect in Caenorhabditis elegans of Alzheimer's Model
Chen_2022_Infect.Drug.Resist_15_1317 A Novel Nomogram for Predicting Risk Factors and Outcomes in Bloodstream Infections Caused by Klebsiella pneumoniae
Cuccaro_2022_Mar.Pollut.Bull_178_113601 Biochemical response of Ficopomatus enigmaticus adults after exposure to organic and inorganic UV filters
Cunha_2022_Int.J.Pharm__121720 Thermosensitive in situ hydrogels of rivastigmine-loaded lipid-based nanosystems for nose-to-brain delivery: characterisation, biocompatibility, and drug deposition studies
da_2022_Neurotoxicol_90_184 Shedding light on the toxicity of SARS-CoV-2-derived peptide in non-target covid-19 organisms: a study involving inbred and outbred mice
Ding_2022_J.Oncol_2022_7633720 miRNA-Mediated Low Expression of EPHX3 Is Associated with Poor Prognosis and Tumor Immune Infiltration in Head and Neck Squamous Cell Carcinomas
Dzydzan_2022_Molecules_27_ Biological Activity of Extracts of Red and Yellow Fruits of Cornus mas L.-An In Vitro Evaluation of Antioxidant Activity, Inhibitory Activity against alpha-Glucosidase, Acetylcholinesterase, and Binding Capacity to Human Serum Albumin
El Maaiden_2022_Molecules_27_ A Comparative Study between Conventional and Advanced Extraction Techniques: Pharmaceutical and Cosmetic Properties of Plant Extracts
Erukainure_2022_Biomed.Pharmacother_149_112863 Cannabidiol improves glucose utilization and modulates glucose-induced dysmetabolic activities in isolated rats' peripheral adipose tissues
Fang_2022_Oxid.Med.Cell.Longev_2022_3773415 Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation
Farfan-Garcia_2022_J.Trace.Elem.Med.Biol_72_126979 Identification and evaluation of boronic compounds ameliorating cognitive deficit in orchiectomized rats
Formagio_2022_J.Ethnopharmacol__115220 Exploration of essential oil from Psychotria poeppigiana as an anti-hyperalgesic and anti-acetylcholinesterase agent: Chemical composition, biological activity and molecular docking
Good_2022_Int.J.Pharm.Compd_26_110 The Potential Effects of a Compounded Methylcobalamin Nasal Spray on Short-term Memory Loss After Intracranial Hemorrhage: A Case Report
Goto_2022_BMC.Nephrol_23_128 Clinical value of serum cholinesterase levels in Nephrotic syndrome: an observational study
Grabner_2022_J.Am.Chem.Soc__ Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes
Gulec_2022_Mol.Divers__ Cytotoxic effect, enzyme inhibition, and in silico studies of some novel N-substituted sulfonyl amides incorporating 1,3,4-oxadiazol structural motif
Guo_2022_Front.Genet_13_814295 A Heterozygous LMF1 Gene Mutation (c.1523C>T), Combined With an LPL Gene Mutation (c.590G>A), Aggravates the Clinical Symptoms in Hypertriglyceridemia
Haji_2022_Molecules_27_ Design, Synthesis, and Evaluation of Novel 2H-Benzo[b][1,4]thiazin-3(4H)-one Derivatives as New Acetylcholinesterase Inhibitors
Hsieh_2022_Front.Cardiovasc.Med_9_831730 Association Between Cholinesterase Inhibitors and New-Onset Heart Failure in Patients With Alzheimer's Disease: A Nationwide Propensity Score Matching Study
Imamoglu_2022_Bioorg.Med.Chem.Lett_65_128722 Polyphenolic compounds: Synthesis, assessment of antimicrobial effect and enzymes inhibition against important medicinal enzymes with computational details
Iyer_2022_Expert.Opin.Ther.Pat__1 Soluble epoxide hydrolase inhibitors: an overview and patent review from the last decade
Jarrett_2022_AACE.Clin.Case.Rep_8_93 The Use of Orlistat in an Adult with Lipoprotein Lipase Deficiency: A Case Report
Javorac_2022_Chem.Biol.Interact__109932 Comprehensive insight into the neurotoxic mechanisms of low dose Pb exposure in Wistar rats: Benchmark dose analysis
Joson_2022_BMJ.Case.Rep_15_ Role of intravenous lipid emulsion therapy and packed red blood cell transfusion as adjuvant treatment in the management of a child with severe organophosphate poisoning (chlorpyrifos)
Kalogerakos_2022_Oxf.Med.Case.Reports_2022_omac031 Prolonged complete atrioventricular block due to neostigmine and amiodarone interaction in an amyloidosis patient with left main dissection and postoperative intestinal pseudo-obstruction
Khadrawy_2022_Neuroendocrinology__ The neuroprotective effect of alpha lipoic acid and\/or metformin against the behavioral and neurochemical changes induced by hypothyroidism in rat
Kumar_2022_Bioorg.Med.Chem_61_116742 Advancements in the development of multi-target directed ligands for the treatment of Alzheimer's disease
Li_2022_Mini.Rev.Med.Chem__ Evodiamine-A Privileged Structure with Broad-Ranging Biological Activities
Liang_2022_Mol.Ther.Nucleic.Acids_28_114 The Aptamer Ob2, a novel AChE inhibitor, restores cognitive deficits and alleviates amyloidogenesis in 5FAD transgenic mice
Liu_2022_Anal.Chem_94_5970 Acetylcholinesterase Activity Monitoring and Natural Anti-neurological Disease Drug Screening via Rational Design of Deep Eutectic Solvents and CeO(2)-Co(OH)(2) Nanosheets
Mani_2022_Eur.Rev.Med.Pharmacol.Sci_26_1897 Ciproxifan attenuates the memory impairment induced by lipopolysaccharide through modulation of cholinergic transmission in the mouse brain
Martinez-Herrera_2022_J.Alzheimers.Dis__ Multiadducts of C60 Modulate Amyloid-beta Fibrillation with Dual Acetylcholinesterase Inhibition and Antioxidant Properties: In Vitro and In Silico Studies
Mathew_2022_CNS.Neurol.Disord.Drug.Targets__ Current Drug Targets in Alzheimer's Associated Memory Impairment: A Comprehensive Review
Mehri_2022_J.Biochem.Mol.Toxicol__e23063 The protective effect of resveratrol on diazinon-induced oxidative stress and glucose hemostasis disorder in rats' liver
Mpoulimari_2022_Psychiatr.Genet__ Synthesis of genetic association studies on autism spectrum disorders using a genetic model-free approach
Mu_2022_Oxid.Med.Cell.Longev_2022_2576310 Effects of Peroxiredoxin 6 and Its Mutants on the Isoproterenol Induced Myocardial Injury in H9C2 Cells and Rats
Niazmand_2022_Physiol.Rep_10_e15243 The effect of HTLV1 infection on inflammatory and oxidative parameters in the liver, kidney, and pancreases of BALB\/c mice
Noreen_2022_Biometals__ Correlating the charge transfer efficiency of metallic sulfa-isatins to design efficient NLO materials with better drug designs
Olofinsan_2022_J.Food.Biochem__e14177 Harpephyllum caffrum fruit (wild plum) facilitates glucose uptake and modulates metabolic activities linked to neurodegeneration in isolated rat brain: An in vitro and in silico approach
Orzel_2022_Ann.Agric.Environ.Med_29_143 Assessment of hospitalizations of patients after intoxication with organophosphates used in agriculture
Pacifici_2022_Front.Endocrinol.(Lausanne)_13_842575 Peroxiredoxin 6 Modulates Insulin Secretion and Beta Cell Death via a Mitochondrial Dynamic Network
Pawlowicz_2022_Molecules_27_ Aloe arborescens: In Vitro Screening of Genotoxicity, Effective Inhibition of Enzyme Characteristics for Disease Etiology, and Microbiological Activity
Piletsky_2022_J.Mater.Chem.B__ Modulation of acetylcholinesterase activity using molecularly imprinted polymer nanoparticles
Pothlichet_2022_Front.Immunol_13_824746 Microbial Protein Binding to gC1qR Drives PLA2G1B-Induced CD4 T-Cell Anergy
Przybylowska_2022_J.Enzyme.Inhib.Med.Chem_37_1012 Design, synthesis and biological evaluation of novel N-phosphorylated and O-phosphorylated tacrine derivatives as potential drugs against Alzheimer's disease
Rastija_2022_Molecules_27_ Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action
Ribeiro_2022_Neurotoxicol__ Repeated exposure to chlorpyrifos is associated with a dose-dependent chronic neurobehavioral deficit in adult rats
Rocchetti_2022_Front.Plant.Sci_13_856513 The Hierarchical Contribution of Organic vs. Conventional Farming, Cultivar, and Terroir on Untargeted Metabolomics Phytochemical Profile and Functional Traits of Tomato Fruits
Sadeghi_2022_Clin.Case.Rep_10_e05469 Occurrence of acute cholinergic syndrome in an infant due to donepezil ingestion
Seidl_2022_Front.Mol.Biosci_9_868597 A Comprehensive 2D-LC\/MS Online Platform for Screening of Acetylcholinesterase Inhibitors
Sepulveda_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2112820119 KARRIKIN UP-REGULATED F-BOX 1 (KUF1) imposes negative feedback regulation of karrikin and KAI2 ligand metabolism in Arabidopsis thaliana
Shahid_2022_ACS.Omega_7_9369 Design, Synthesis, and Bioevaluation of Indole Core Containing 2-Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A\/B for the Treatment of Alzheimer Disease
Sharma_2022_Pharmacol.Rep__ Salubrious effects of ulinastatin and quercetin alone or in combination in endothelial dysfunction and vascular dementia
Shen_2022_J.Mater.Chem.B__ A versatile biomimetic multienzyme cascade nanoplatform based on boronic acid-modified metal-organic framework for colorimetric biosensing
Sher_2022_Molecules_27_ Prokinetic and Laxative Effects of Chrozophora tinctoria Whole Plant Extract
Sobstyl_2022_Molecules_27_ Schisandra rubriflora Fruit and Leaves as Promising New Materials of High Biological Potential: Lignan Profiling and Effect-Directed Analysis
Stojkovic_2022_EXCLI.J_21_387 Phlomis fruticosa L. exerts in vitro antineurodegenerative and antioxidant activities and induces prooxidant effect in glioblastoma cell line
Wang_2022_Chemosphere_299_134406 Omics and mechanistic insights into di-(2-ethylhexyl) phthalate degradation in the O(2)-fluctuating estuarine sediments
Wang_2022_J.Ethnopharmacol__115252 Cornuside ameliorates cognitive impairments in scopolamine induced AD mice: Involvement of neurotransmitter and oxidative stress
Wei_2022_Chem.Pharm.Bull.(Tokyo)_70_283 Caulophyine A, a Rare Azapyrene Alkaloid from the Roots of Caulophyllum robustum
Welter_2022_Front.Physiol_13_860868 An Investigation of the Altered Textural Property in Woody Breast Myopathy Using an Integrative Omics Approach
Wunschik_2022_Appl.Biochem.Biotechnol__ Activation and Stabilization of Lipase B from Candida antarctica by Immobilization on Polymer Brushes with Optimized Surface Structure
Xia_2022_Chin.J.Nat.Med_20_210 Bioactive neolignans and lignans from the roots of Paeonia lactiflora
Xiao_2022_Zhonghua.Er.Ke.Za.Zhi_60_360 [A case of delayed-type cholesteryl ester storage disease derived from LIPA gene mutation]
Yaker_2022_Front.Cell.Dev.Biol_10_823450 Extracellular Vesicles From LPS-Treated Macrophages Aggravate Smooth Muscle Cell Calcification by Propagating Inflammation and Oxidative Stress
Yuan_2022_Biomed.Chromatogr__e5380 Development and validation of a LC-MS\/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and diabetic nephropathy mice
Zavala-Ocampo_2022_J.Ethnopharmacol_292_115239 Acetylcholinesterase inhibition and antioxidant activity properties of Petiveria alliacea L
Zeng_2022_Molecules_27_ Design, Synthesis and Bioactivity Evaluation of Coumarin-BMT Hybrids as New Acetylcholinesterase Inhibitors
Zhang_2022_Ecotoxicol.Environ.Saf_236_113482 Sublethal effects of tolfenpyrad on the development, reproduction, and predatory ability of Chrysoperla sinica
Zhang_2022_Oxid.Med.Cell.Longev_2022_4594956 Plin5 Bidirectionally Regulates Lipid Metabolism in Oxidative Tissues
Abdel-Aziz_2022_Arch.Pharm.(Weinheim)__e2200024 New pyrimidine\/thiazole hybrids endowed with analgesic, anti-inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX-2\/sEH dual inhibition
Alasmari_2022_CNS.Neurol.Disord.Drug.Targets__ Therapeutic effects of thymoquinone on Alzheimer's disease through modulating amyloid beta neurotoxicity and neuro-inflammatory cytokine levels
Almaliti_2022_Molecules_27_ Discovery of Novel Epoxyketone Peptides as Lipase Inhibitors
Amir_2022_PLoS.One_17_e0264207 Isolation and optimization of extracellular PHB depolymerase producer Aeromonas caviae Kuk1-(34) for sustainable solid waste management of biodegradable polymers
Arnipalli_2022_Chirality__ New enantioselective liquid chromatography method development and validation of dipeptidyl peptidase IV inhibitors using a macrocyclic glycopeptide (vancomycin) chiral stationary phase under polar ionic mode condition
Chen_2022_Ann.Transl.Med_10_303 Design, synthesis, and evaluation of 8-aminoquinoline-melatonin derivatives as effective multifunctional agents for Alzheimer's disease
de Souza_2022_J.Hazard.Mater_434_128814 Toxicity induced via ingestion of naturally-aged polystyrene microplastics by a small-sized terrestrial bird and its potential role as vectors for the dispersion of these pollutants
Dhillon_2022_Funct.Integr.Genomics__ Whole genome sequencing of spotted stem borer, Chilo partellus, reveals multiple genes encoding enzymes for detoxification of insecticides
do Nascimento_2022_RSC.Adv_12_3027 Lipase-catalyzed acylation of levoglucosan in continuous flow: antibacterial and biosurfactant studies
Drummond_2022_Acta.Neuropathol.Commun_10_53 The amyloid plaque proteome in early onset Alzheimer's disease and Down syndrome
Duran-Cristiano_2022_Cent.Nerv.Syst.Agents.Med.Chem__ Cholinesterase activity in the eye?
Fu_2022_Food.Chem_387_132919 CRISPR-Cas12a based fluorescence assay for organophosphorus pesticides in agricultural products
Ganie_2022_Toxicology__153181 Mechanisms and treatment strategies of organophosphate pesticide induced neurotoxicity in humans: A critical appraisal
Ghayur_2022_Biomed.Res.Int_2022_4849464 Trigonella foenum-graecum Methanolic Extract on Isolated Smooth Muscles and Acetylcholinesterase Enzyme: An In Vitro and Mechanistic In Silico Investigation
Greenfield_2022_Alzheimers.Dement.(N.Y)_8_e12274 A novel process driving Alzheimer's disease validated in a mouse model: Therapeutic potential
Hayes_2022_Front.Cell.Dev.Biol_10_856261 Perlecan, A Multi-Functional, Cell-Instructive, Matrix-Stabilizing Proteoglycan With Roles in Tissue Development Has Relevance to Connective Tissue Repair and Regeneration
Iheanacho_2022_Drug.Chem.Toxicol__1 Effects of burnt tire-ash on Na(+)\/K(+), Ca(2+)-ATPase, serum immunoglobulin and brain acetylcholinesterase activities in clarias gariepinus (Burchell, 1822)
Kantarci_2022_Brain.Commun_4_fcac013 Longitudinal atrophy in prodromal dementia with Lewy bodies points to cholinergic degeneration
Klainbart_2022_Vet.Rec__e1633 Clinical manifestations, laboratory findings, treatment and outcome of acute organophosphate or carbamate intoxication in 39 cats
Li_2022_RSC.Adv_12_7911 Facile preparation of fluorescent water-soluble non-conjugated polymer dots and fabricating an acetylcholinesterase biosensor
Li_2022_J.Toxicol.Environ.Health.A__1 Biological activities and gene expression of detoxifying enzymes in Tribolium castaneum induced by Moutan cortex essential oil
Liu_2022_J.Environ.Sci.Health.B__1 Graphitic-phase C(3)N(4) nanosheets combined with MnO(2) nanosheets for sensitive fluorescence quenching detection of organophosphorus pesticides
Liu_2022_Curr.Alzheimer.Res__ Co-treatment with the herbal medicine SIP3 and donepezil improves memory and depression in the mouse model of Alzheimer's disease
Liu_2022_BMC.Cardiovasc.Disord_22_177 The benefit of exercise rehabilitation guided by 6-minute walk test on lipoprotein-associated phospholipase A2 in patients with coronary heart disease undergoing percutaneous coronary intervention: a prospective randomized controlled study
Lusty_2022_RSC.Adv_12_8119 A flexible kinetic assay efficiently sorts prospective biocatalysts for PET plastic subunit hydrolysis
Maxeiner_2022_Front.Mol.Neurosci_15_838262 Of Humans and Gerbils- Independent Diversification of Neuroligin-4 Into X- and Y-Specific Genes in Primates and Rodents
Mehreen_2022_RSC.Adv_12_1788 Synthesis, solid state self-assembly driven by antiparallel Pi-Pi stacking and {...H-C-C-F}(2) dimer synthons, and in vitro acetyl cholinesterase inhibition activity of phenoxy pendant isatins
Panico_2022_Environ.Pollut__119290 Field mixtures of currently used pesticides in agricultural soil pose a risk to soil invertebrates
Pei_2022_J.Agric.Food.Chem__ Transport, Stability, and In Vivo Hypoglycemic Effect of a Broccoli-Derived DPP-IV Inhibitory Peptide VPLVM
Pohanka_2022_Mini.Rev.Med.Chem__ Caffeine Role in the Age-Related Neurodegenerative Diseases, A Review
Pohanka_2022_Int.J.Anal.Chem_2022_2623155 A Butyrylcholinesterase Camera Biosensor Tested for Carbofuran and Paraoxon Assay
Rui_2022_BMC.Plant.Biol_22_194 Genome-wide expression analysis of carboxylesterase (CXE) gene family implies GBCXE49 functional responding to alkaline stress in cotton
Shaban_2022_Cardiovasc.Toxicol__ Exosomes Derived from Senescent Endothelial Cells Contain Distinct Pro-angiogenic miRNAs and Proteins
Sinitsyn_2022_Front.Toxicol_4_838729 From Qualitative to Quantitative AOP: A Case Study of Neurodegeneration
Song_2022_Food.Chem_387_132896 Single-atom Ce-N-C nanozyme bioactive paper with a 3D-printed platform for rapid detection of organophosphorus and carbamate pesticide residues
Tao_2022_RSC.Adv_12_5265 A novel electrochemical sensing platform based on the esterase extracted from kidney bean for high-sensitivity determination of organophosphorus pesticides
Thiemann_2022_Front.Physiol_13_859671 Role of Endothelial Cell Lipoprotein Lipase for Brown Adipose Tissue Lipid and Glucose Handling
Wang_2022_Anal.Chim.Acta_1205_339717 Constructing bifunctional metal-organic framework based nanozymes with fluorescence and oxidase activity for the dual-channel detection of butyrylcholinesterase
Wei_2022_Phytochemistry__113182 Triterpenoids as bivalent and dual inhibitors of acetylcholinesterase\/butyrylcholinesterase from the fruiting bodies of Inonotus obliquus
Wu_2022_Nutr.Diet__ The sarcopenia index is an effective predictor for malnutrition in patients with liver cirrhosis
Xu_2022_Food.Funct__ Enhancement of DPP-IV inhibitory activity and the capacity for enabling GLP-1 secretion through RADA16-assisted molecular designed rapeseed peptide nanogels
Yin_2022_J.Hazard.Mater_434_128824 Toxicological effects of tris(1,3-dichloro-2-propyl) phosphate in oyster Crassostrea gigas using proteomic and phosphoproteomic analyses
Zhang_2022_Mol.Genet.Genomics__ Response of xenobiotic biodegradation and metabolic genes in Tribolium castaneum following eugenol exposure
Zhao_2022_Pestic.Biochem.Physiol_183_105057 Transcriptome analysis and the identification of genes involved in the metabolic pathways of fenoxaprop-P-ethyl in rice treated with isoxadifen-ethyl hydrolysate
Adithya_2022_J.Assoc.Physicians.India_70_11 RDW a Predictor in OP Poisoning
Abdel-Tawab_2022_PLoS.One_17_e0265184 Evaluation of gene expression of PLEKHS1, AADAC, and CDKN3 as novel genomic markers in gastric carcinoma
Abuobeid_2022_Int.J.Mol.Sci_23_ Squalene through Its Post-Squalene Metabolites Is a Modulator of Hepatic Transcriptome in Rabbits
Adeniyi_2022_Nutr.Neurosci__1 Neuropharmacological effects of honey in lipopolysaccharide-induced neuroinflammation, cognitive impairment, anxiety and motor impairment
Aghamolaei_2022_RSC.Adv_12_5971 Preparation and characterization of stable core\/shell Fe(3)O(4)@Au decorated with an amine group for immobilization of lipase by covalent attachment
Al-Hakim_2022_Pharm.Nanotechnol__ Effect of Banana (Musa sp.) Peels Extract in Nanoemulsion Dosage Forms for the Improvement of Memory: In vitro & In vivo Studies
Al-Shammari_2022_Genes.(Basel)_13_ Identification and Characterization of Variants in Intron 6 of the LPL Gene Locus among a Sample of the Kuwaiti Population
Ardalan_2022_Br.J.Pharmacol__ Reelin cells and sex-dependent synaptopathology in autism following postnatal immune activation
Bari_2022_Molecules_27_ Effects of Artemisia macrocephala Jacquem on Memory Deficits and Brain Oxidative Stress in Streptozotocin-Induced Diabetic Mice
Bilen_2022_Chem.Biol.Interact__109956 Bioactive sulfonyl hydrazones with alkyl derivative: Characterization, ADME properties, molecular docking studies and investigation of inhibition on choline esterase enzymes for the diagnosis of Alzheimer's disease
Bini_2022_Biomolecules_12_ The Fibrinogen-like Domain of ANGPTL3 Facilitates Lipolysis in 3T3-L1 Cells by Activating the Intracellular Erk Pathway
Boiangiu_2022_Plants.(Basel)_11_ Angelica purpurascens (Av-Lall.) Gilli. Essential Oil Improved Brain Function via Cholinergic Modulation and Antioxidant Effects in the Scopolamine-Induced Zebrafish (Danio rerio) Model
Brunetti_2022_Eur.J.Med.Chem_237_114358 Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease
Burton_2022_J.Pediatr.Gastroenterol.Nutr__ Long-term Sebelipase Alfa Treatment in Children and Adults With Lysosomal Acid Lipase Deficiency
Capan_2022_ChemMedChem__ Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitors
Cardona-Ruda_2022_Toxins.(Basel)_14_ Anti-Neurotoxins from Micrurus mipartitus in the Development of Coral Snake Antivenoms
Cardoso-Vera_2022_Sci.Total.Environ__155359 Multi-biomarker approach to evaluate the neurotoxic effects of environmentally relevant concentrations of phenytoin on adult zebrafish Danio rerio
Chandra_2022_J.Assoc.Physicians.India_70_11 Serum Amylase and Lipase Estimation in Diabetic Ketoacidosis
Chen_2022_Compr.Rev.Food.Sci.Food.Saf__ Rebuilding the lid region from conformational and dynamic features to engineering applications of lipase in foods: Current status and future prospects
Chen_2022_Molecules_27_2420 Phytochemical Composition, Antioxidant Activity, alpha-Glucosidase and Acetylcholinesterase Inhibitory Activity of Quinoa Extract and Its Fractions
Chhunchha_2022_Cells_11_ Switching of Redox Signaling by Prdx6 Expression Decides Cellular Fate by Hormetic Phenomena Involving Nrf2 and Reactive Oxygen Species
Daniali_2022_Toxics_10_ Molecular Evidence on the Inhibitory Potential of Metformin against Chlorpyrifos-Induced Neurotoxicity
Daniel_2022_Biology.(Basel)_11_ Assessment of Paracetamol Toxic Effects under Varying Seawater pH Conditions on the Marine Polychaete Hediste diversicolor Using Biochemical Endpoints
Ding_2022_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_42_100984 Toxin diversity revealed by de novo transcriptome assembly for venom gland in two species of spiders (Trichonephila clavata and Sinopoda pengi)
Erbacher_2022_Cells_11_ Distinct CholinomiR Blood Cell Signature as a Potential Modulator of the Cholinergic System in Women with Fibromyalgia Syndrome
Fan_2022_Environ.Sci.Pollut.Res.Int__ Different toxicity to liver and gill of zebrafish by selenium nanoparticles derived from bio\/chemical methods
Fortibui_2022_ACS.Appl.Bio.Mater__ Near-Infrared Fluorescence Probe for Specific Detection of Acetylcholinesterase and Imaging in Live Cells and Zebrafish
Georgiou_2022_Molecules_27_ Conformational Properties of New Thiosemicarbazone and Thiocarbohydrazone Derivatives and Their Possible Targets
Gong_2022_Indian.J.Microbiol_62_280 Production of Red Pigments by a Newly Isolated Talaromyces aurantiacus Strain with LED Stimulation for Screen Printing
Gookin_2022_Front.Synaptic.Neurosci_14_852227 Complementary Use of Super-Resolution Imaging Modalities to Study the Nanoscale Architecture of Inhibitory Synapses
Huo_2022_Cost.Eff.Resour.Alloc_20_19 Cost-effectiveness of pharmacological therapies for people with Alzheimer's disease and other dementias: a systematic review and meta-analysis
Hussain_2022_Molecules_27_2468 Attenuation of Scopolamine-Induced Amnesia via Cholinergic Modulation in Mice by Synthetic Curcumin Analogs
Hutten_2022_J.Alzheimers.Dis__ Targeting the Beta-2-Adrenergic Receptor and the Risk of Developing Alzheimer's Disease: A Retrospective Inception Cohort Study
Jansa_2022_Org.Biomol.Chem__ Synthesis and cholinesterase inhibitory activity study of Amaryllidaceae alkaloid analogues with N-methyl substitution
Karapetyan_2022_Biophys.Chem_286_106820 Citrullination of adenosine deaminase impairs its binding to dipeptidyl peptidase IV
Koca_2022_Chem.Biodivers__e202200015 Design and Synthesis of Novel Dual Cholinesterase Inhibitors: In Vitro Inhibition Studies Supported with Molecular Docking
Kretzschmar_2022_Metabolites_12_ PNPLA6\/NTE, an Evolutionary Conserved Phospholipase Linked to a Group of Complex Human Diseases
Li_2022_J.Int.Med.Res_50_3000605221093303 Negative correlation between early recovery and lipoprotein-associated phospholipase A2 levels after intravenous thrombolysis
Lim_2022_Int.J.Mol.Sci_23_ Identification of Novel Natural Product Inhibitors against Matrix Metalloproteinase 9 Using Quantum Mechanical Fragment Molecular Orbital-Based Virtual Screening Methods
Lite_2022_Environ.Toxicol__ Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety-like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae
Liu_2022_Anal.Chem_94_6540 Metal-Organic Frameworks-Based Immobilized Enzyme Microreactors Integrated with Capillary Electrochromatography for High-Efficiency Enzyme Assay
Medetalibeyoglu_2022_J.Biomol.Struct.Dyn__1 Synthesis and acetylcholinesterase enzyme inhibitory effects of some novel 4,5-Dihydro-1H-1,2,4-triazol-5-one derivatives\; an in vitro and in silico study
Milano_2022_Cancer.Sci__ Liposomal irinotecan (Onivyde): Exemplifying the benefits of nanotherapeutic drugs
Nachtigall_2022_Toxins.(Basel)_14_ Differences in PLA(2) Constitution Distinguish the Venom of Two Endemic Brazilian Mountain Lanceheads, Bothrops cotiara and Bothrops fonsecai
Olasehinde_2022_Nutr.Neurosci__1 Effect of diet supplemented with African Star Apple Fruit Pulp on purinergic, cholinergic and monoaminergic enzymes, TNF-alpha expression and redox imbalance in the brain of hypertensive rats
Oyeleke_2022_Heliyon_8_e09255 Therapeutic effects of crude extracts of Bacopa floribunda on beta-amyloid 1-42-induced Alzheimer's disease via suppression of dyslipidemia, systemic inflammation and oxidative stress in male Wistar Rats
Pang_2022_Cell.Rep_39_110698 Bladder epithelial cell phosphate transporter inhibition protects mice against uropathogenic Escherichia coli infection
Parfait_2022_Evid.Based.Complement.Alternat.Med_2022_7576132 Antioxidant and Anticholinesterase Properties of the Aqueous Extract of Balanites aegyptiaca L. Delile Fruit Pulp on Monosodium Glutamate-Induced Excitotoxicity in Swiss Mice
Peng_2022_Front.Microbiol_13_880118 Esterases From Bifidobacteria Exhibit the Conversion of Albiflorin in Gut Microbiota
Pottoo_2022_Pharmaceuticals.(Basel)_15_ Thymoquinone: Review of Its Potential in the Treatment of Neurological Diseases
Qiu_2022_J.Mol.Biol__167600 Allosteric regulation of the soluble epoxide hydrolase by nitro fatty acids using a combined experimental and computational approach
Ramirez-Carreto_2022_J.Vis.Exp__ Identification of Hemolytic and Phospholipase Activity in Crude Extracts from Sea Anemones by Straightforward Bioassays
Rudzki_2022_Mil.Med__ Five-Year PTSD Symptom Remission in Two Patients Following Treatment With Rivastigmine
Sahin_2022_Comput.Biol.Med_146_105514 A single-molecule with multiple investigations: Synthesis, characterization, computational methods, inhibitory activity against Alzheimer's disease, toxicity, and ADME studies
Santos_2022_Biomedicines_10_ HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine
Sharma_2022_Bioengineered_13_10518 Mechano-chemical and biological energetics of immobilized enzymes onto functionalized polymers and their applications
Song_2022_Toxics_10_ Esculetin and Fucoidan Attenuate Autophagy and Apoptosis Induced by Zinc Oxide Nanoparticles through Modulating Reactive Astrocyte and Proinflammatory Cytokines in the Rat Brain
Tabassum_2022_Molecules_27_ Phytochemical Profiling, Antioxidant, Anti-Inflammatory, Thrombolytic, Hemolytic Activity In Vitro and In Silico Potential of Portulacaria afra&\;nbsp
Ullah_2022_CNS.Neurol.Disord.Drug.Targets__ Natural products as bioactive agents in the prevention of dementia
Wang_2022_Ecotoxicol.Environ.Saf_237_113540 Enrichment of polystyrene microplastics induces histological damage, oxidative stress, Keap1-Nrf2 signaling pathway-related gene expression in loach juveniles (Paramisgurnus dabryanus)
Wang_2022_Mar.Drugs_20_ Simultaneous Inhibitory Effects of All-Trans Astaxanthin on Acetylcholinesterase and Oxidative Stress
Yadav_2022_J.Assoc.Physicians.India_70_11 Study of Sick Euthyroid Syndrome in Organophosphate Poisoning
Yaginuma_2022_Molecules_27_ Current Knowledge on Mammalian Phospholipase A(1), Brief History, Structures, Biochemical and Pathophysiological Roles
Yamashita_2022_Front.Aging.Neurosci_14_810206 Long-Term Effect of Acetylcholinesterase Inhibitors on the Dorsal Attention Network of Alzheimer's Disease Patients: A Pilot Study Using Resting-State Functional Magnetic Resonance Imaging
Yoon_2022_BMC.Geriatr_22_353 Patterns of dementia treatment in older adults with Parkinson's disease using nationwide medical claims data
Zhang_2022_Anal.Chim.Acta_1206_339792 Water-soluble non-conjugated polymer dots with strong green fluorescence for sensitive detection of organophosphate pesticides
Zhang_2022_BMC.Plant.Biol_22_213 The effects of mepiquat chloride (DPC) on the soluble protein content and the activities of protective enzymes in cotton in response to aphid feeding and on the activities of detoxifying enzymes in aphids
Zhang_2022_J.Appl.Toxicol__ Combined effects of chlorpyrifos and cyfluthrin on neurobehavior and neurotransmitter levels in larval zebrafish
Tal_2022_Nat.Plants__ A conformational switch in the SCF-D3\/MAX2 ubiquitin ligase facilitates strigolactone signalling
Agha_2022_J.Enzyme.Inhib.Med.Chem_37_1241 Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening
Almadiy_2022_Environ.Sci.Pollut.Res.Int__ Bioactivity of Deverra tortuosa essential oil, its nanoemulsion, and phenylpropanoids against the cowpea weevil, a stored grain pest with eco-toxicological evaluations
Cao_2022_Chemosphere__134691 Toxic effects of glyphosate on the intestine, liver, brain of carp and on epithelioma papulosum cyprinid cells: Evidence from in vivo and in vitro research
Contador-Kelsall_2022_Conserv.Physiol_10_coac024 Sublethal pesticide exposure influences behaviour, but not condition in a widespread Australian lizard
de_2022_Sci.Rep_12_6815 Impact of immobilization strategies on the activity and recyclability of lipases in nanomagnetic supports
de_2022_Arthritis.Res.Ther_24_99 The angiopoietin-like protein 4, apolipoprotein C3, and lipoprotein lipase axis is disrupted in patients with rheumatoid arthritis
Kasama_2022_Chem.Pharm.Bull.(Tokyo)_70_391 Lipase-Catalyzed Kinetic Resolution of C(1)-Symmetric Heterocyclic Biaryls
Kim_2022_Technol.Cancer.Res.Treat_21_15330338221093146 Carboxyl Esterase-TRAIL Expressing Human Adipose Stem Cells Inhibit Tumor Growth in Castration-Resistant Prostate Cancer-Bearing Mice with Less Toxicity
Kitsuka_2022_Sci.Rep_12_6923 A novel soluble epoxide hydrolase vaccine protects murine cardiac muscle against myocardial infarction
Kumar_2022_J.Ethnopharmacol__115327 Genus Rauvolfia: A review of its ethnopharmacology, phytochemistry, quality control\/quality assurance, pharmacological activities and clinical evidence
Lize_2022_Environ.Res__113348 Prenatal exposure to organophosphate pesticides and autism spectrum disorders in 11-year-old children in the French PELAGIE cohort
Lombardi_2022_Eur.J.Clin.Pharmacol__ Long-term use of pharmacological treatment in Alzheimer's disease: a retrospective cohort study in real-world clinical practice
Reguigui_2022_J.Chromatogr.A_1673_463057 Profile comparison and valorization of Tunisian Salvia aegyptiaca and S. verbenaca aerial part extracts via hyphenated high-performance thin-layer chromatography
Reiniers_2022_Methods.Mol.Biol_2451_721 Optimal Use of 2',7'-Dichlorofluorescein Diacetate in Cultured Hepatocytes
Rojas_2022_Neurotoxicol__ Time-dependent neuropathology in rats following organophosphate-induced status epilepticus
Sanchez-Martinez_2022_Food.Chem.X_13_100242 Neuroprotective potential of terpenoid-rich extracts from orange juice by-products obtained by pressurized liquid extraction
Santos_2022_Food.Chem.Toxicol__113084 Theoretical assessment of the performances of commercial oximes on the reactivation of acetylcholinesterase inhibited by the nerve agent A-242 (novichok)
Sierra_2022_Biomed.Pharmacother_150_113016 In vitro and in silico analysis of galanthine from Zephyranthes carinata as an inhibitor of acetylcholinesterase
Sun_2022_Dis.Markers_2022_6154675 The Relationship between Intracarotid Plaque Neovascularization and Lp (a) and Lp-PLA2 in Elderly Patients with Carotid Plaque Stenosis
Wang_2022_Bioresour.Technol_355_127244 Biochemical characterization of an engineered bifunctional xylanase\/feruloyl esterase and its synergistic effects with cellulase on lignocellulose hydrolysis
Zhang_2022_Anal.Chim.Acta_1207_339708 Acetylcholinesterase-capped mesoporous silica gated switches for selective detection of high-toxicity organophosphate compounds
Aguera_2022_Environ.Toxicol.Pharmacol__103874 Risk evaluation of occupational exposure of southern Brazilian flower farmers to pesticides potentially leading to cholinesterase inhibition and metals exposure
Agyekum_2022_Parasit.Vectors_15_163 Relationship between temperature and Anopheles gambiae sensu lato mosquitoes' susceptibility to pyrethroids and expression of metabolic enzymes
Bashiri_2022_J.Biotechnol_351_30 The limitations of the current protein classification tools in identifying lipolytic features in putative bacterial lipase sequences
Beltman_2022_Virchows.Arch__ Diagnostic accuracy of calretinin and acetylcholinesterase staining of rectal suction biopsies in Hirschsprung disease examined by unexperienced pathologists
Boi_2022_Sci.Rep_12_7322 Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions
Bonhomme_2022_J.Exp.Bot__ Synthesis and Signalling of Strigolactone and KAI2-Ligand signals in bryophytes
Bononi_2022_J.Med.Chem__ Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives
Braeckmans_2022_Int.J.Pharm__121807 Orlistat disposition in the human jejunum and the effect of lipolysis inhibition on bile salt concentrations and composition
Cui_2022_Oxid.Med.Cell.Longev_2022_2122856 Plin5, a New Target in Diabetic Cardiomyopathy
Ferreira_2022_Environ.Toxicol.Pharmacol__103870 Environmentally relevant Manganese concentrations evoke anxiety phenotypes in adult zebrafish
Fghihi-Zarandi_2022_Toxicol.Ind.Health__7482337221096315 Occupational risk assessment of organophosphates with an emphasis on psychological and oxidative stress factors
Harrington_2022_EBioMedicine_80_104041 Butyrylcholinesterase is a potential biomarker for Sudden Infant Death Syndrome
He_2022_J.Econ.Entomol__ The Acaricidal Potential of a New Agent GC16 for Tetranychus pueraricola (Acari: Tetranychidae) Based on Developmental Performance and Physiological Enzyme Activity
Kalari_2022_J.Alzheimers.Dis__ A Cobalt-Containing Compound as a Stronger Inhibitor than Galantamine to Inhibit Acetylcholinesterase Activity: A New Drug Candidate for Alzheimer's Disease Treatment
Khoba_2022_Appl.Biochem.Biotechnol__ Isolation, Characterization, and In Silico Interaction Studies of Bioactive Compounds from Caesalpinia bonducella with Target Proteins Involved in Alzheimer's Disease
Kiyak_2022_Pancreatology__ Lipase elevation on admission predicts worse clinical outcomes in patients with COVID-19
Larkin_2022_JAMA_327_1642 First Donepezil Transdermal Patch Approved for Alzheimer Disease
Liang_2022_Sci.Total.Environ__155747 Evaluation of the toxicity effects of microplastics and cadmium on earthworms
Mani_2022_Saudi.J.Biol.Sci_29_2738 Aqueous Ajwa dates seeds extract improves memory impairment in type-2 diabetes mellitus rats by reducing blood glucose levels and enhancing brain cholinergic transmission
Masaki_2022_Appl.Microbiol.Biotechnol__ Features and application potential of microbial urethanases
Milicevic_2022_Saudi.Pharm.J_30_369 Use of connectivity index and simple topological parameters for estimating the inhibition potency of acetylcholinesterase
Mukherjee_2022_Sci.Total.Environ__155716 Antioxidant enzyme activity and pathophysiological responses in the freshwater walking catfish, Clarias batrachus Linn under sub-chronic and chronic exposures to the neonicotinoid, Thiamethoxam
Myers_2022_Drug.Metab.Rev__1 Metabolism of the areca alkaloids - toxic and psychoactive constituents of the areca (betel) nut
Nguyen_2022_J.Chem.Theory.Comput__ Determination of Multidirectional Pathways for Ligand Release from the Receptor: A New Approach Based on Differential Evolution
Ozturk_2022_Biol.Trace.Elem.Res__ Selenium Heals the Chlorpyrifos-Induced Oxidative Damage and Antioxidant Enzyme Levels in the Rat Tissues
Paspati_2022_Exp.Appl.Acarol__ Transcriptomic profile of the predatory mite Amblyseius swirskii (Acari: Phytoseiidae) on different host plants
Pawin_2022_Nat.Prod.Res__1 Phytochemical analysis, antioxidant, and anticholinesterase activities of ethanolic extracts from five ginger plants in Thailand
Peng_2022_Talanta_246_123525 A green photocatalytic-biosensor for colorimetric detection of pesticide (carbaryl) based on inhibition of acetylcholinesterase
Pervaiz_2022_J.Biomol.Struct.Dyn__1 Comparative in-vitro anti-inflammatory, anticholinesterase and antidiabetic evaluation: computational and kinetic assessment of succinimides cyano-acetate derivatives
Phukon_2022_Curr.Genet__ Cold-adaptive traits identified by comparative genomic analysis of a lipase-producing Pseudomonas sp. HS6 isolated from snow-covered soil of Sikkim Himalaya and molecular simulation of lipase for wide substrate specificity
Rajkumar_2022_Curr.Res.Pharmacol.Drug.Discov_3_100100 Galantamine tethered hydrogel as a novel therapeutic target for streptozotocin-induced Alzheimer's disease in Wistar rats
Ramakrishna_2022_J.Clin.Exp.Hepatol_12_672 Living-Donor Liver Transplantation for Late-Onset Lysosomal Acid Lipase Deficiency
Shabbir_2022_Environ.Sci.Pollut.Res.Int__ Differential neuroprotective effect of curcuminoid formulations in aluminum chloride-induced Alzheimer's disease
Shahrivari_2022_Sci.Rep_12_7234 A comprehensive study on essential oil compositions, antioxidant, anticholinesterase and antityrosinase activities of three Iranian Artemisia species
Sosnowska_2022_Food.Funct__ Proanthocyanidins as the main pancreatic lipase inhibitors in chokeberry fruits
Toledo_2022_Elife_11_ MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
Van Cong_2022_Ecotoxicol.Environ.Saf_238_113578 Sensitivity of cholinesterase activity in juvenile giant freshwater prawn (Macrobrachium rosenbergii de Man, 1879) to organophosphate diazinon
Yang_2022_Ann.Palliat.Med_11_1381 Effects of the hemolytic index on the test results of a dry chemistry analyzer and a verification of the hemolytic interference threshold
Yang_2022_Chemosphere_301_134697 Effects of urea application on the reproduction of Pardosa pseudoannulata: Field and laboratory studies
Zhou_2022_AMB.Express_12_51 Whole genome sequencing and analysis of fenvalerate degrading bacteria Citrobacter freundii CD-9
Zuniga-Venegas_2022_Environ.Mol.Mutagen__ DNA damage in a Chilean population exposed to pesticides and its association with PON1 (Q192R and L55M) susceptibility biomarker
Alanazi_2022_Plants.(Basel)_11_ Acaricidal, Larvacidal, and Repellent Activity of Elettaria cardamomum Essential Oil against Hyalomma anatolicum Ticks Infesting Saudi Arabian Cattle
Altilia_2022_Clin.Chem.Lab.Med__ Biological variation of serum cholinesterase catalytic concentrations
Alvarez-Vergara_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_258_109367 Biochemical and osmoregulatory responses of the African clawed frog experimentally exposed to salt and pesticide
Amir_2022_Molecules_27_ In Vitro and In Silico Anti-Acetylcholinesterase Activity from Macaranga tanarius and Syzygium jambos
Andrade_2022_PLoS.One_17_e0268292 Suillin: A mixed-type acetylcholinesterase inhibitor from Suillus luteus which is used by Saraguros indigenous, southern Ecuador
Anoush_2022_ACS.Omega_7_13861 Clavulanic Acid: A Novel Potential Agent in Prevention and Treatment of Scopolamine-Induced Alzheimer's Disease
Ayed-Boussema_2022_Neurotoxicol__ Fenpyroximate induced cytotoxicity and genotoxicity in Wistar rat brain and in human neuroblastoma (SH-SY5Y) cells: involvement of oxidative stress and apoptosis
Baetz_2022_Anal.Bioanal.Chem__ High-performance thin-layer chromatography in combination with an acetylcholinesterase-inhibition bioassay with pre-oxidation of organothiophosphates to determine neurotoxic effects in storm, waste, and surface water
Bhat_2022_Metab.Brain.Dis__ Neuroprotective Effects of Theobromine in permanent bilateral common carotid artery occlusion rat model of cerebral hypoperfusion
Blini_2022_J.Environ.Sci.Health.B__1 Efficiency of the removal of tetraethyl pyrophosphate (TEPP) pesticide in water: use of cork granules as a natural adsorbent on acetylcholinesterase activity in neuronal PC12 cell
Bugay_2022_Front.Neurosci_16_866899 Effects of Sublethal Organophosphate Toxicity and Anti-cholinergics on Electroencephalogram and Respiratory Mechanics in Mice
Burzynski_2022_Neurobiol.Stress_18_100446 Pyridostigmine bromide elicits progressive and chronic impairments in the cholinergic anti-inflammatory pathway in the prefrontal cortex and hippocampus of male rats
Bzowka_2022_PLoS.Comput.Biol_18_e1010119 Evolution of tunnels in alpha\/beta-hydrolase fold proteins-What can we learn from studying epoxide hydrolases?
Cano-Rocabayera_2022_Aquat.Toxicol_248_106193 An integrated biomarker approach: Non-monotonic responses to cadmium exposure in the suckermouth catfish Hypostomus plecostomus
Capitao_2022_Nanomaterials.(Basel)_12_ Single and Mixture Toxicity of Boron and Vanadium Nanoparticles in the Soil Annelid Enchytraeus crypticus: A Multi-Biomarker Approach
Caputo_2022_BMC.Complement.Med.Ther_22_142 Chemical composition, antibiofilm, cytotoxic, and anti-acetylcholinesterase activities of Myrtus communis L. leaves essential oil
Chen_2022_Contrast.Media.Mol.Imaging_2022_7832564 Predictive Value of Perioperative Cytokine Levels on the Risk for In-Stent Restenosis in Acute Myocardial Infarction Patients
Choi_2022_Cell.Mol.Life.Sci_79_294 Prenatal glucocorticoid exposure selectively impairs neuroligin 1-dependent neurogenesis by suppressing astrocytic FGF2-neuronal FGFR1 axis
Choi_2022_Plants.(Basel)_11_ Biogenesis and Lipase-Mediated Mobilization of Lipid Droplets in Plants
Cui_2022_Front.Physiol_13_885030 Integrated Proteomic and Metabolomic Analyses of Chicken Ovary Revealed the Crucial Role of Lipoprotein Lipase on Lipid Metabolism and Steroidogenesis During Sexual Maturity
Damo_2022_Plants.(Basel)_11_ Neuroprotective Potential of Guiera senegalensis (Combretaceae) Leaf Hydroethanolic Extract against Cholinergic System Dysfunctions and Oxidative Stress in Scopolamine-Induced Cognitive Impairment in Zebrafish (Danio rerio)
de Araujo-Silva_2022_Molecules_27_2692 Enzymatic Synthesis of Fatty Acid Isoamyl Monoesters from Soybean Oil Deodorizer Distillate: A Renewable and Ecofriendly Base Stock for Lubricant Industries
De Paep_2022_Cell.Transplant_31_9636897221096160 Utility of Islet Cell Preparations From Donor Pancreases After Euthanasia
Doi_2022_PLoS.One_17_e0266839 Prognostic value of nutritional parameters in systolic heart failure with renal dysfunction
Dong_2022_Front.Pharmacol_13_877872 Erigeron breviscapus (Vant.) Hand-Mazz.: A Promising Natural Neuroprotective Agent for Alzheimer's Disease
El-Ganainy_2022_Neurochem.Res__ Intranasal Oxytocin Attenuates Cognitive Impairment, beta-Amyloid Burden and Tau Deposition in Female Rats with Alzheimer's Disease: Interplay of ERK1\/2\/GSK3beta\/Caspase-3
Fallatah_2022_Sensors.(Basel)_22_ Sensitive Biosensor Based on Shape-Controlled ZnO Nanostructures Grown on Flexible Porous Substrate for Pesticide Detection
Fathi_2022_Mol.Biol.Rep__ Evaluation of potential of miR-8073 and miR-642 as diagnostic markers in pancreatic cancer
Fortuna_2022_ChemMedChem__ Synthesis and Exploitation of the Biological Profile of Novel Guanidino Xylofuranose Derivatives
Funayama_2022_Brain.Nerve_74_685 [Treatment and Care for Elderly Patients with Dementia with Lewy Bodies Presenting with Delusional Misidentification Syndrome Including Capgras Syndrome: Severe Psychiatric Symptoms Associated with Dementia with Lewy Bodies]
Gad_2022_Plants.(Basel)_11_ Chemometric Analysis Based on GC-MS Chemical Profiles of Three Stachys Species from Uzbekistan and Their Biological Activity
Gajbhiye_2022_Curr.Drug.Deliv__ An In Vivo Investigation of Ascorbic Acid Tethered Polymeric Nanoparticles for Effectual Brain Transport of Rivastigmine
Ghide_2022_Food.Chem_390_133171 Immobilization of Rhizomucor miehei lipase on magnetic multiwalled carbon nanotubes towards the synthesis of structured lipids rich in sn-2 palmitic acid and sn-1,3 oleic acid (OPO) for infant formula use
Giresha_2022_Sci.Rep_12_7649 Group IIA secreted phospholipase A(2) inhibition by elemolic acid as a function of anti-inflammatory activity
Guzman-Mendoza_2022_Nanomaterials.(Basel)_12_ A Novel Method for Carbon Nanotube Functionalization Using Immobilized Candida antarctica Lipase
Haley_2022_Environ.Health.Perspect_130_57001 Evaluation of a Gene-Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case-Control Study Drawn from the U.S. Military Health Survey's National Population Sample
Hameed_2022_Int.J.Biol.Macromol_211_653 Evaluation of synthetic 2-aryl quinoxaline derivatives as alpha-amylase, alpha-glucosidase, acetylcholinesterase, and butyrylcholinesterase inhibitors
Hassall_2022_Orphanet.J.Rare.Dis_17_193 Why them, why me, why us? The experiences of parents of children with lysosomal acid lipase deficiency: an interpretative phenomenological analysis study
Haydar_2022_Bratisl.Lek.Listy_123_428 Evaluation of patients with acute pancreatitis associated with SARS-CoV-2 (COVID-19)\; The importance of lipase\/lymphocyte ratio in predicting mortality
Holotiuk_2022_Exp.Oncol_44_75 Evaluation of the efficiency of alpha-lipoic acid and Ipidacrine hydrochloride for the prevention of paclitaxel-induced peripheral neuropathy according to the total neuropathy score
Houngkamhang_2022_Sensors.(Basel)_22_ Portable Deep Learning-Driven Ion-Sensitive Field-Effect Transistor Scheme for Measurement of Carbaryl Pesticide
Hu_2022_Comput.Math.Methods.Med_2022_5712219 Paeoniflorin Can Improve Acute Lung Injury Caused by Severe Acute Pancreatitis through Nrf2\/ARE Pathway
Hussein_2022_Plants.(Basel)_11_1124 The Valorization of Spent Coffee Ground Extract as a Prospective Insecticidal Agent against Some Main Key Pests of Phaseolus vulgaris in the Laboratory and Field
Jin_2022_Theranostics_12_3196 Neuronal STAT3\/HIF-1alpha\/PTRF axis-mediated bioenergetic disturbance exacerbates cerebral ischemia-reperfusion injury via PLA2G4A
Kawashima_2022_BMC.Neurol_22_175 Memantine for the patients with mild cognitive impairment in Parkinson's disease: a pharmacological fMRI study
Kumari_2022_CNS.Neurol.Disord.Drug.Targets__ Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases
Kunka_2022_Nucleic.Acids.Res__ CalFitter 2.0: Leveraging the power of singular value decomposition to analyse protein thermostability
Kutluk_2022_Environ.Technol__1 Lipase catalysis: An environmentally friendly production for Polyol esters (biolubricant) from Microalgae oil
Lagardere_2022_Front.Synaptic.Neurosci_14_835427 High-Resolution Fluorescence Imaging Combined With Computer Simulations to Quantitate Surface Dynamics and Nanoscale Organization of Neuroligin-1 at Synapses
Lamb_2022_Environ.Sci.Process.Impacts__ Towards a comprehensive understanding of malathion degradation: comparison of degradation reactions under alkaline and radical conditions
Lamba_2022_Int.J.Mol.Sci_23_ Kinetic Modeling of Time-Dependent Enzyme Inhibition by Pre-Steady-State Analysis of Progress Curves: The Case Study of the Anti-Alzheimer's Drug Galantamine
Li_2022_NPJ.Biofilms.Microbiomes_8_39 Patatin-like phospholipase CapV in Escherichia coli - morphological and physiological effects of one amino acid substitution
Li_2022_BMC.Pulm.Med_22_192 Peroxiredoxin 6 mediates the protective function of curcumin pretreatment in acute lung injury induced by serum from patients undergoing one-lung ventilation in vitro
Li_2022_Front.Bioeng.Biotechnol_10_894046 Synthesis of Poly(Hexamethylene Succinate-Co-Ethylene Succinate) Copolymers With Different Physical Properties and Enzymatic Hydrolyzability by Regulating the Ratio of Monomer
Li_2022_Front.Physiol_13_877153 Enhanced Degradation of Juvenile Hormone Promotes Reproductive Diapause in the Predatory Ladybeetle Coccinella Septempunctata
Liu_2022_Nanomaterials.(Basel)_12_ Highly Selective Detection of Paraoxon in Food Based on the Platform of Cu Nanocluster\/MnO(2) Nanosheets
Long_2022_Front.Nutr_9_852012 Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats
Madubuike_2022_Molecules_27_ Characterisation of a Novel Acetyl Xylan Esterase (BaAXE) Screened from the Gut Microbiota of the Common Black Slug (Arion ater)
Maglioni_2022_Nat.Commun_13_2620 Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans
Magrath_2022_J.Neuropsychiatry.Clin.Neurosci__appineuropsych21060166 Advances in Treatment of Frontotemporal Dementia
Moreira_2022_J.Alzheimers.Dis.Rep_6_177 Neuroprotective Effects of Cholinesterase Inhibitors: Current Scenario in Therapies for Alzheimer's Disease and Future Perspectives
Mundy_2022_J.Pharmacol.Toxicol.Methods_115_107173 Diisopropylfluorophosphate (DFP) volatizes and cross-contaminates wells in a common 96-well plate format used in zebrafish larvae toxicology studies
Naik_2022_Curr.Drug.Discov.Technol__ Synthesis, Characterisation and Docking Studies of Thioxoquinoline Derivatives as Potential Anti-Alzheimer Agents
Noro_2022_Biotechnol.J__e2100523 Chemical modification of lipases: A powerful tool for activity improvement
Ogunsuyi_2022_Biomarkers__1 Neuroprotective properties of Solanum leaves in Transgenic Drosophila melanogaster model of Alzheimer's disease
Paltinean_2022_Plants.(Basel)_11_ Biological Activities of Some Isoquinoline Alkaloids from Fumaria schleicheri Soy. Will
Peng_2022_Nat.Prod.Res__1 Novel phenylpropanoids and isoflavone glycoside are isolated and identified from the carob pods (Ceratonia siliqua L.)
Penttinen_2022_Molecules_27_ Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans
Pfavayi_2022_Int.Arch.Allergy.Immunol__1 The Identification and Characterization of Immunoreactive Fungal Proteins Recognized by Sera from Zimbabweans Sensitized to Fungi
Planas-Iglesias_2022_Nucleic.Acids.Res__ LoopGrafter: a web tool for transplanting dynamical loops for protein engineering
Podsiedlik_2022_Int.J.Mol.Sci_23_ The Influence of Selected Antipsychotic Drugs on Biochemical Aspects of Alzheimer's Disease
Prabhakar_2022_J.Biomol.Struct.Dyn__1 Computational analysis of marine algal compounds for obesity management against pancreatic lipase
Pradhan_2022_J.Mol.Neurosci__ Recent Advances Towards Diagnosis and Therapeutic Fingerprinting for Alzheimer's Disease
Qiu_2022_Parasit.Vectors_15_172 Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers
Ramires_2022_Mol.Neurobiol__ Rivastigmine Reverses the Decrease in Synapsin and Memory Caused by Homocysteine: Is There Relation to Inflammation?
Rastogi_2022_Plant.Mol.Biol__ Arabidopsis GELP7 functions as a plasma membrane-localized acetyl xylan esterase, and its overexpression improves saccharification efficiency
Rosato_2022_Polymers.(Basel)_14_ Enzymatic Degradation of the Most Common Aliphatic Bio-Polyesters and Evaluation of the Mechanisms Involved: An Extended Study
Rostami_2022_J.Mol.Neurosci__ Sinomenine Attenuates Trimethyltin-Induced Cognitive Decline via Targeting Hippocampal Oxidative Stress and Neuroinflammation
Saikia_2022_Indian.J.Pharmacol_54_102 Evaluation of anti-amnesic effect of Conyza bonariensis in rats
Saito_2022_Anal.Chem__ Molecular Interactions between an Enzyme and Its Inhibitor for Selective Detection of Limonene
Salinas_2022_Plants.(Basel)_11_1188 Chemical Composition, Enantiomeric Distribution and Anticholinesterase and Antioxidant Activity of the Essential Oil of Diplosthephium juniperinum
Shao_2022_Theor.Appl.Genet__ Identification of closely associated SNPs and candidate genes with seed size and shape via deep re-sequencing GWAS in soybean
Shervington_2022_Molecules_27_ Investigating the Stability of Six Phenolic TMZ Ester Analogues, Incubated in the Presence of Porcine Liver Esterase and Monitored by HPLC
Spelta_2022_Toxicol.Appl.Pharmacol__116068 Chronic escalating-dose and acute binge cocaine treatments change the hippocampal cholinergic muscarinic system on drug presence and after withdrawal
Strong_2022_J.Pediatr.Gastroenterol.Nutr__ Lessons Learned from the Long-Term Use of Enzyme Replacement Therapy in the Treatment of Lysosomal Acid Lipase Deficiency
Subaharan_2022_Environ.Sci.Pollut.Res.Int__ Ultrasound-assisted nanoemulsion of Trachyspermum ammi essential oil and its constituent thymol on toxicity and biochemical aspect of Aedes aegypti
Suryavanshi_2022_Metab.Brain.Dis__ Asiatic acid attenuates aluminium chloride-induced behavioral changes, neuronal loss and astrocyte activation in rats
Tarabasz_2022_Int.J.Mol.Sci_23_ The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors-In Silico and In Vitro Studies
Tripathi_2022_3.Biotech_12_116 Therapeutic effects of CoenzymeQ10, Biochanin A and Phloretin against arsenic and chromium induced oxidative stress in mouse (Mus musculus) brain
Vasina_2022_Adv.Drug.Deliv.Rev_183_114143 Tools for computational design and high-throughput screening of therapeutic enzymes
Venkatesh_2022_J.Org.Chem_87_6730 Multicomponent Synthesis of S-Benzyl Dithiocarbamates from para-Quinone Methides and Their Biological Evaluation for the Treatment of Alzheimer's Disease
Wang_2022_Front.Chem_10_855281 A Portable Fluorescent Hydrogel-Based Device for On-Site Quantitation of Organophosphorus Pesticides as Low as the Sub-ppb Level
Wang_2022_Nutrients_14_ Chlorophyll Inhibits the Digestion of Soybean Oil in Simulated Human Gastrointestinal System
Xiang_2022_J.Mater.Chem.B__ Ratiometric imaging of butyrylcholinesterase activity in mice with nonalcoholic fatty liver using an AIE-based fluorescent probe
Xu_2022_Nutrients_14_ Distinct AMPK-Mediated FAS\/HSL Pathway Is Implicated in the Alleviating Effect of Nuciferine on Obesity and Hepatic Steatosis in HFD-Fed Mice
Yang_2022_Front.Endocrinol.(Lausanne)_13_856954 The Multiple Biological Functions of Dipeptidyl Peptidase-4 in Bone Metabolism
Yeltekin_2022_J.Trace.Elem.Med.Biol_72_126996 Borax exerts protective effect against ferrocene-induced neurotoxicity in Oncorhynchus mykiss
Yener_2022_Int.J.Psychophysiol__ Treatment effects on event-related EEG potentials and oscillations in Alzheimer's disease
Young_2022_J.Lipid.Res__100223 Isomeric lipid signatures reveal compartmentalized fatty acid metabolism in cancer
Zhang_2022_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_278_121329 A novel indene-chalcone-based fluorescence probe with lysosome-targeting for detection of endogenous carboxylesterases and bioimaging
Zhang_2022_J.Res.Med.Sci_27_33 Hemoperfusion in combination with hemofiltration for acute severe organophosphorus pesticide poisoning: A systematic review and meta-analysis
Zhang_2022_Int.J.Mol.Sci_23_4911 Populus euphratica Phospholipase Ddelta Increases Salt Tolerance by Regulating K(+)\/Na(+) and ROS Homeostasis in Arabidopsis
Zhao_2022_Analyst__ A sensitive fluorescence biosensor based on metal ion-mediated DNAzyme activity for amplified detection of acetylcholinesterase
Zhu_2022_J.Enzyme.Inhib.Med.Chem_37_1375 Design, synthesis, and evaluation of novel O-alkyl ferulamide derivatives as multifunctional ligands for treating Alzheimer's disease
Zitouni_2022_Sci.Total.Environ__155872 Metabolomic disorders unveil hepatotoxicity of environmental microplastics in wild fish Serranus scriba (Linnaeus 1758)
Zuniga_2022_Neurologia.(Engl.Ed)_37_287 Pharmacogenetic studies in Alzheimer disease
Zuo_2022_BMC.Surg_22_183 Strategy to small intestine obstruction caused by Crohn's disease on the basis of transnasal ileus tube insertion
Adedara_2022_Ecotoxicol.Environ.Saf_239_113635 Induction of aggression and anxiety-like responses by perfluorooctanoic acid is accompanied by modulation of cholinergic- and purinergic signaling-related parameters in adult zebrafish
Al Qahtani_2022_Chem.Biodivers__ Chemical profile, antioxidant and enzyme inhibition activities of natural Saudi Sidr and Talh honeys
Al-Asmari_2022_Saudi.J.Biol.Sci_29_103307 Arabica coffee and olive oils mitigate malathion-induced nephrotoxicity in rat: In silico, immunohistochemical and biochemical evaluation
Bachollet_2022_Org.Biomol.Chem_20_3619 An expanded palette of fluorogenic HaloTag probes with enhanced contrast for targeted cellular imaging
Basheer_2022_Interact.J.Med.Res__ Bacopa monnieri in the treatment of dementia due to Alzheimer's disease: A systematic review of randomised controlled trials
Bhattarai_2022_FEMS.Microbiol.Ecol_98_ The potential for bacteria from carbon-limited deep terrestrial environments to participate in chlorine cycling
Cannazza_2022_Biotechnol.Adv__107985 Mycobacterium smegmatis acyltransferase: The big new player in biocatalysis
Degre_2022_Med.Sci.(Paris)_38_497 [Mycobacterium tuberculosis lipases, new targets in the fight against tuberculosis]
Du_2022_Cell.Death.Dis_13_488 FASN promotes lymph node metastasis in cervical cancer via cholesterol reprogramming and lymphangiogenesis
Freyria_2022_Commun.Biol_5_500 Salinity tolerance mechanisms of an Arctic Pelagophyte using comparative transcriptomic and gene expression analysis
Gopi_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109379 Protective effects of dietary supplementation of probiotic Bacillus licheniformis Dahb1 against ammonia induced immunotoxicity and oxidative stress in Oreochromis mossambicus
Guo_2022_Drug.Des.Devel.Ther_16_1495 Design, Synthesis and Biological Evaluation of New 3,4-Dihydro-2(1H)-Quinolinone-Dithiocarbamate Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease
Hunt_2022_Org.Biomol.Chem__ Synthesis of 6'-galactosyllactose, a deviant human milk oligosaccharide, with the aid of Candida antarctica lipase-B
Isik_2022_Z.Naturforsch.C.J.Biosci__ Synthesis, characterization, molecular docking, dynamics simulations, and in silico absorption, distribution, metabolism, and excretion (ADME) studies of new thiazolylhydrazone derivatives as butyrylcholinesterase inhibitors
Kim_2022_Oxid.Med.Cell.Longev_2022_7157444 Effect of Ethyl Acetate Fraction from Eucommia ulmoides Leaves on PM(2.5)-Induced Inflammation and Cognitive Dysfunction
Liu_2022_Biosens.Bioelectron_211_114392 New fluorescent probe with recognition moiety of bipiperidinyl reveals the rise of hepatocellular carboxylesterase activity during heat shock
Malak_2022_Saudi.J.Biol.Sci_29_103302 In silico approaches to develop herbal acaricides against R. (Boophilus) Microplus and In vitro Anti-Tick activities of selected medicinal plants
Oyeleye_2022_J.Food.Biochem__e14261 Plantain peels restore sexual performance, hormonal imbalance, and modulate nitric oxide production and key enzymes of penile function in paroxetine-sexually impaired male rats
Pohl_2022_Neuronal.Signal_6_NS20210030 Neuroligins in neurodevelopmental conditions: how mouse models of de novo mutations can help us link synaptic function to social behavior
Pruksaphon_2022_Toxicon__ Immunogenicity of snake alpha-neurotoxins and the CD4 T cell epitopes
Saleh_2022_Pharm.Res__ Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC(50) Values in Aging and Alzheimer's Disease, Using the Physiologically Based LeiCNS-PK3.0 Model
Sallam_2022_Biomed.Pharmacother_151_113160 Quercetin alleviated multi-walled carbon nanotubes-induced neurotoxicity in mice through inhibition of oxidation, inflammation, and pyroptosis
Schmitz_2022_Neurobiol.Learn.Mem_192_107637 Effects of methylphenidate after a long period of discontinuation include changes in exploratory behavior and increases brain activities of Na(+),K(+)-ATPase and acetylcholinesterase
Shamarao_2022_Food.Funct__ Antiobesity drug-likeness properties and pancreatic lipase inhibition of a novel low molecular weight lutein oxidized product, LOP6
Sher_2022_Braz.J.Biol_84_e260566 GC-MS analysis of organic fractions of Chrozophora tinctoria (L.) A.Juss. and their prokinetic propensity in animal models
Simic_2022_J.Comp.Neurol__ Prenatal development of the human entorhinal cortex
Tancheva_2022_J.Alzheimers.Dis__ Beneficial Effects of Snail Helix aspersa Extract in an Experimental Model of Alzheimer's Type Dementia
Tian_2022_Bioorg.Med.Chem.Lett_70_128805 Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors
Wang_2022_Phytochemistry__113221 The production of broad-spectrum antibiotics from phytopathogen Epicoccum sorghinum by culturing in host edible mushroom Thelephora ganbajun extract
Wang_2022_Chem.Asian.J__ Recent advances of chemosensors for nerve agents
Yin_2022_World.J.Clin.Cases_10_2072 Prognostic and biological role of the N-Myc downstream-regulated gene family in hepatocellular carcinoma
Zeng_2022_J.Ethnopharmacol__115361 Anoectochilus roxburghii flavonoids extract ameliorated the memory decline and reduced neuron apoptosis via modulating SIRT1 signaling pathway in senescent mice
Abderrezag_2022_J.Chromatogr.A_1675_463147 One-step sustainable extraction of Silymarin compounds of wild Algerian milk thistle (Silybum marianum) seeds using Gas Expanded Liquids
Adewole_2022_Curr.Drug.Discov.Technol__ Computer-aided identification of cholinergic and monoaminergic inhibitory flavonoids from Hibiscus sabdariffa L
Adomeniene_2022_Plants.(Basel)_11_ Health Beneficial Phytochemicals in Dioscorea caucasica Lipsky Leaves and Tubers and Their Inhibitory Effects on Physiologically Important Enzymes
Atanasova_2022_Molecules_27_ Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors
Badalamenti_2022_Molecules_27_ Reuse of Food Waste: The Chemical Composition and Health Properties of Pomelo (Citrus maxima) Cultivar Essential Oils
Baharin_2022_Plants.(Basel)_11_1330 Post-Proline Cleaving Enzymes (PPCEs): Classification, Structure, Molecular Properties, and Applications
Batawi_2022_Int.J.Neurosci__1 Ginkgo biloba extract mitigates the neurotoxicity of AlCl(3) in Alzheimer rat's model: Role of Apolipoprotein E4 and clusterin genes in stimulating ROS generation and apoptosis
Borowiec_2022_Food.Chem_391_133281 Polyphenols composition and the biological effects of six selected small dark fruits
Cachatra_2022_Med.Chem__ Revisiting Purine Nucleoside Cholinesterase Inhibitors - An Experimental Glycon Structure\/Activity Relationship Study
Cardozo-Munoz_2022_Molecules_27_ Multitarget Action of Xanthones from Garcinia mangostana against alpha-Amylase, alpha-Glucosidase and Pancreatic Lipase
Chaiyana_2022_Molecules_27_ Enhancement of Cholinesterase Inhibition of Alpinia galanga (L.) Willd. Essential Oil by Microemulsions
Chen_2022_J.Obstet.Gynaecol__1 Screening models combining maternal characteristics and multiple markers for the early prediction of preeclampsia in pregnancy: a nested case-control study
da Silva Mesquita_2022_Molecules_27_ In Vitro and In Silico Evaluation of Cholinesterase Inhibition by Alkaloids Obtained from Branches of Abuta panurensis Eichler
de Oliveira_2022_Molecules_27_ Pharmacological Approaches to the Treatment of Dementia in Down Syndrome: A Systematic Review of Randomized Clinical Studies
Di Paola_2022_Toxics_10_ Environmental Toxicity Assessment of Sodium Fluoride and Platinum-Derived Drugs Co-Exposure on Aquatic Organisms
Durmaz_2022_Molecules_27_3091 Screening of Carbonic Anhydrase, Acetylcholinesterase, Butyrylcholinesterase, and alpha-Glycosidase Enzyme Inhibition Effects and Antioxidant Activity of Coumestrol
El-Kharraf_2022_Pharmaceuticals.(Basel)_15_ Unassisted and Carbon Dioxide-Assisted Hydro- and Steam-Distillation: Modelling Kinetics, Energy Consumption and Chemical and Biological Activities of Volatile Oils
Fernandez-Bolanos_2022_Expert.Opin.Ther.Pat__ Butyrylcholinesterase inhibitors as potential anti-Alzheimer's agents: an updated patent review (2018-present)
Francois_2022_Biomedicines_10_ Long-Term Anxiety-like Behavior and Microbiota Changes Induced in Mice by Sublethal Doses of Acute Sarin Surrogate Exposure
Gao_2022_Genes.(Basel)_13_ Identification and Validation of Reliable Reference Genes for Gene Expression Studies in Koelreuteria paniculata
Guglielmi_2022_Expert.Opin.Ther.Pat__ An updated patent review on monoamine oxidase (MAO) inhibitors
Han_2022_Stem.Cell.Res.Ther_13_221 Human umbilical cord mesenchymal stem cells-derived exosomes for treating traumatic pancreatitis in rats
Herrera-Mayorga_2022_Molecules_27_ Insecticidal Activity of Organic Extracts of Solidago graminifolia and Its Main Metabolites (Quercetin and Chlorogenic Acid) against Spodoptera frugiperda: An In Vitro and In Silico Approach
Hofmann_2022_Chemistry__e202200786 Synthesis and Biological Evaluation of Flavonoid-Cinnamic Acid Amide Hybrids with Distinct Activity against Neurodegeneration in Vitro and in Vivo
Huang_2022_Int.J.Physiol.Pathophysiol.Pharmacol_14_90 Improved Aitongxiao prescription (I-ATXP) induces apoptosis, cell cycle arrest and blocks exosomes release in hepatocellular carcinoma (HCC) cells
Isibor_2022_J.Trace.Elem.Med.Biol_73_127001 D-ribose-L-cysteine reduces oxidative stress and inflammatory cytokines to mitigate liver damage, and memory decline induced by copper sulfate in mice
Kamkaen_2022_Molecules_27_ Mucuna pruriens Seed Aqueous Extract Improved Neuroprotective and Acetylcholinesterase Inhibitory Effects Compared with Synthetic L-Dopa
Khan_2022_Micromachines.(Basel)_13_ Monotheca buxifolia Driven Synthesis of Zinc Oxide Nano Material Its Characterization and Biomedical Applications
Lee_2022_Biology.(Basel)_11_ Toxic Effects on Oxidative Stress, Neurotoxicity, Stress, and Immune Responses in Juvenile Olive Flounder, Paralichthys olivaceus, Exposed to Waterborne Hexavalent Chromium
Li_2022_Br.J.Cancer__ The dark side of synaptic proteins in tumours
Li_2022_Molecules_27_3090 Novel and Potent Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease from Natural (+\/-)-7,8-Dihydroxy-3-methyl-isochroman-4-one
Lin_2022_Aquat.Toxicol_248_106197 Toxic effects of waterborne benzylparaben on the growth, antioxidant capacity and lipid metabolism of Nile tilapia (Oreochromis niloticus)
Liu_2022_Bioorg.Chem_126_105875 Discovery of novel tacrine derivatives as potent antiproliferative agents with CDKs inhibitory property
Loer_2022_Pharmaceutics_14_ Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug-Drug-Gene Interaction Predictions
MacDonald_2022_Drugs.Aging__ Current Therapies and Drug Development Pipeline in Lewy Body Dementia: An Update
Malik_2022_Molecules_27_ Chalcone Scaffolds Exhibiting Acetylcholinesterase Enzyme Inhibition: Mechanistic and Computational Investigations
Mana_2022_Molecules_27_ Non-Alcoholic Fatty Liver Disease in Long-Term Type 2 Diabetes: Role of rs738409 PNPLA3 and rs499765 FGF21 Polymorphisms and Serum Biomarkers
Menon_2022_Drugs__ Pharmacotherapy of Generalized Myasthenia Gravis with Special Emphasis on Newer Biologicals
Namour_2022_Clin.Pharmacokinet__ Filgotinib: A Clinical Pharmacology Review
Naz_2022_PLoS.One_17_e0264460 Interaction of fungal lipase with potential phytotherapeutics
Nazari_2022_Mini.Rev.Med.Chem__ A Comprehensive Review on Soluble Epoxide Hydrolase Inhibitors Evaluating Their Structure-Activity Relationship
Onder_2022_J.Mol.Graph.Model_115_108210 Identifying highly effective coumarin-based novel cholinesterase inhibitors by in silico and in vitro studies
Oyeniyi_2022_Food.Chem.Toxicol__113189 Phospholipids modifications, genotoxic and anticholinesterase effects of pepper fruit (Dennettia tripetala G. Baker) extract in Swiss mice
Paidi_2022_Biomed.Pharmacother_151_113086 Medha Plus - A novel polyherbal formulation ameliorates cognitive behaviors and disease pathology in models of Alzheimer's disease
Pan_2022_Front.Nutr_9_892426 Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure-Activity Relationship, Kinetics and Interaction Mechanism
Park_2022_Biosensors.(Basel)_12_ Scalable Functionalization of Polyaniline-Grafted rGO Field-Effect Transistors for a Highly Sensitive Enzymatic Acetylcholine Biosensor
Permatasari_2022_Clin.Nutr.ESPEN_49_232 Kombucha drink enriched with sea grapes (Caulerpa racemosa) as potential functional beverage to contrast obesity: An in vivo and in vitro approach
Rao_2022_PLoS.One_17_e0269036 Extending the lore of curcumin as dipteran Butyrylcholine esterase (BChE) inhibitor: A holistic molecular interplay assessment
Rhoades_2022_Genes.(Basel)_13_ Computational Saturation Mutagenesis to Investigate the Effects of Neurexin-1 Mutations on AlphaFold Structure
Rodrigues_2022_Plants.(Basel)_11_ The Medicinal Halophyte Frankenia laevis L. (Sea Heath) Has In Vitro Antioxidant Activity, alpha-Glucosidase Inhibition, and Cytotoxicity towards Hepatocarcinoma Cells
Roy_2022_Curr.Drug.Metab__ Targeting the Pathological Hallmarks of Alzheimer's Disease Through Nanovesicle-aided Drug Delivery Approach
Salau_2022_J.Pharm.Pharmacol__ Caffeic acid regulates glucose homeostasis and inhibits purinergic and cholinergic activities while abating oxidative stress and dyslipidaemia in fructose-streptozotocin-induced diabetic rats
Sampietro_2022_Pharmaceuticals.(Basel)_15_ Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis
Seong_2022_J.Toxicol.Environ.Health.A__1 An exploratory study\; the gap between real reference interval and currently used reference interval of RBC AChE activities in South Korea
Shabbir_2022_Front.Nutr_9_880361 Effect of Fermentation on the Bioactive Compounds of the Black Soybean and Their Anti-Alzheimer's Activity
Sraphet_2022_Biology.(Basel)_11_ Application of Hierarchical Clustering to Analyze Solvent-Accessible Surface Area Patterns in Amycolatopsis lipases
Stiefel_2022_Food.Chem_391_133263 Non-target bioactive compound profiles of coffee roasts and preparations
Temviriyanukul_2022_Pharmaceuticals.(Basel)_15_ Mangifera indica 'Namdokmai' Prevents Neuronal Cells from Amyloid Peptide Toxicity and Inhibits BACE-1 Activities in a Drosophila Model of Alzheimer's Amyloidosis
Trifan_2022_Antioxidants.(Basel)_11_ Unveiling the Phytochemical Profile and Biological Potential of Five Artemisia Species
Tung_2022_J.Complement.Integr.Med__ Molecular docking and molecular dynamics approach to identify potential compounds in Huperzia squarrosa for treating Alzheimer's disease
Tuzimski_2022_Molecules_27_3222 Determination of Anti-Alzheimer's Disease Activity of Selected Plant Ingredients
Wei_2022_Insects_13_ Genome-Wide Identification and Analysis of Lipases in Fig Wasps (Chalcidoidea, Hymenoptera)
Zheng_2022_Anal.Chim.Acta_1212_339913 In-situ preparation of hollow CdCoS(2) heterojunction with enhanced photocurrent response for highly photoelectrochemical sensing of organophosphorus pesticides
Allard_2022_Chem.Biol.Interact__109996 Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning
Allen_2022_Cochrane.Database.Syst.Rev_6_CD011574 Interventions for preventing falls in Parkinson's disease
Alma'abadi_2022_N.Biotechnol__ Identification of Lipolytic Enzymes Using High-Throughput Single-cell Screening and Sorting of a Metagenomic Library
Al-Waili_2022_Front.Genet_13_886182 The Genetic Spectrum of Familial Hypertriglyceridemia in Oman
Arya_2022_Front.Nutr_9_871183 Application of Green Technologies in Design-Based Extraction of Celastrus paniculatus (Jyotishmati) Seeds, SEM, GC-MS Analysis, and Evaluation for Memory Enhancing Potential
Bhat_2022_Front.Neurosci_16_884345 Natural Therapeutics in Aid of Treating Alzheimer's Disease: A Green Gateway Toward Ending Quest for Treating Neurological Disorders
Breljak_2022_Mutat.Res.Genet.Toxicol.Environ.Mutagen_876-877_503443 Long-term effects of melatonin and resveratrol on aging rats: A multi-biomarker approach
Delgado_2022_ACS.Appl.Mater.Interfaces__ Zirconium Metal-Organic Polyhedra with Dual Behavior for Organophosphate Poisoning Treatment
D'Este_2022_Int.J.Mol.Sci_23_ Latrotoxin-Induced Neuromuscular Junction Degeneration Reveals Urocortin 2 as a Critical Contributor to Motor Axon Terminal Regeneration
Dhaliwal_2022_Neurochem.Res__ Tetramethylpyrazine Attenuates Cognitive Impairment Via Suppressing Oxidative Stress, Neuroinflammation, and Apoptosis in Type 2 Diabetic Rats
Elfsmark_2022_Inhal.Toxicol_34_145 Ammonia exposure by intratracheal instillation causes severe and deteriorating lung injury and vascular effects in mice
Fabris_2022_Int.J.Mol.Sci_23_ Detection of VAMP Proteolysis by Tetanus and Botulinum Neurotoxin Type B In Vivo with a Cleavage-Specific Antibody
Fasakin_2022_Inflammopharmacology__ The modulatory effects of alkaloid extracts of Cannabis sativa, Datura stramonium, Nicotiana tabacum and male Carica papaya on neurotransmitter, neurotrophic and neuroinflammatory systems linked to anxiety and depression
Fuentes-Jaime_2022_Biodegradation__ Concerted action of extracellular and cytoplasmic esterase and urethane-cleaving activities during Impranil biodegradation by Alicycliphilus denitrificans BQ1
Furze_2022_Br.J.Clin.Pharmacol__ Phase 1 and pre-clinical profiling of ESM-HDAC391, a myeloid-targeted histone deacetylase inhibitor, shows enhanced pharmacology and monocytopaenia
Garcia_2022_PLoS.One_17_e0269129 New compounds from heterocyclic amines scaffold with multitarget inhibitory activity on Abeta aggregation, AChE, and BACE1 in the Alzheimer disease
Glovak_2022_Respir.Physiol.Neurobiol__103924 Fentanyl and Neostigmine Delivered to Mouse Prefrontal Cortex Differentially Alter Breathing
Gorberg_2022_Mol.Neurobiol__ Motor-like Tics are Mediated by CB(2) Cannabinoid Receptor-dependent and Independent Mechanisms Associated with Age and Sex
Gorecki_2022_Trends.Pharmacol.Sci__ Countermeasures in organophosphorus intoxication: pitfalls and prospects
Ha_2022_BMC.Geriatr_22_480 Association of cognitive enhancers and incident seizure risk in dementia: a population-based study
Huang_2022_Pain.Res.Manag_2022_4819910 Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats
Ishola_2022_Brain.Res_1789_147958 Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement
Karlsson_2022_Toxicol.In.Vitro_80_105317 Chlorine exposure induces Caspase-3 independent cell death in human lung epithelial cells
Kawashima_2022_Sci.Rep_12_9100 Rapid imaging of lung cancer using a red fluorescent probe to detect dipeptidyl peptidase 4 and puromycin-sensitive aminopeptidase activities
Li_2022_Bull.Entomol.Res__1 Identification and expression patterns of candidate carboxylesterases in Carposina sasakii Matsumura (Lepidoptera: Carposinidae), an important pest of fruit trees
Li_2022_Front.Microbiol_13_853744 Identification and Comparative Genomic Analysis of Type VI Secretion Systems and Effectors in Klebsiella pneumoniae
Maleita_2022_Front.Plant.Sci_13_867803 Juglone and 1,4-Naphthoquinone-Promising Nematicides for Sustainable Control of the Root Knot Nematode Meloidogyne luci
Mashimo_2022_Biol.Pharm.Bull_45_675 Non-neuronal Cholinergic Muscarinic Acetylcholine Receptors in the Regulation of Immune Function
Masurkar_2022_Drugs.Aging__ Risk of Serious Adverse Events Associated With Individual Cholinesterase Inhibitors Use in Older Adults With Dementia: A Population-Based Cohort Study
Moayedzadeh_2022_Food.Res.Int_156_111306 Emulsion gels loaded with pancreatic lipase: Preparation from spontaneously made emulsions and assessment of the rheological, microscopic and cargo release properties
Mohamed_2022_Environ.Sci.Pollut.Res.Int__ Boswellic acids ameliorate neurodegeneration induced by AlCl(3): the implication of Wnt\/beta-catenin pathway
Moutayakine_2022_Bioorg.Med.Chem_68_116807 Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease
Mu_2022_J.Cancer.Res.Ther_18_411 Effect of lentivirus-mediated peroxiredoxins 6 gene silencing on the phenotype of human gastric cancer BGC-823 cells
Naeem_2022_Pflugers.Arch__ Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth
Nobre_2022_Chemosphere__135169 Combined effects of polyethylene spiked with the antimicrobial triclosan on the swamp ghost crab (Ucides cordatus\; Linnaeus, 1763)
Parsa_2022_Mol.Med_28_60 Enhanced parasympathetic cholinergic activity with galantamine inhibited lipid-induced oxidative stress in obese African Americans
Pereira_2022_J.Cell.Biochem__ In silico analyses of acetylcholinesterase (AChE) and its genetic variants in interaction with the anti-Alzheimer drug Rivastigmine
Pollok_2022_Chemistry__ A General Electro-Synthesis Approach to Amaryllidaceae Alkaloids
Posta_2022_Beilstein.J.Org.Chem_18_549 Synthesis of sulfur karrikin bioisosteres as potential neuroprotectives
Rodrigues_2022_EFSA.J_20_e200419 Monitoring of pesticide amount in fruit and vegetables by a fluorescence-based sensor
Rogala_2022_Anal.Bioanal.Chem__ Voltammetric lipase activity assay based on dilinolein and a modified carbon paste electrode
Romero-Fernandez_2022_ChemSusChem__ Biocatalytic production of a Nylon 6 precursor from caprolactone in continuous flow
Rosenberg_2022_Microorganisms_10_ The GDSL-Lipolytic Enzyme Lip1 Is Required for Full Virulence of the Cucurbit Pathogenic Bacterium Acidovorax citrulli
Ru_2022_Front.Psychiatry_13_896794 Repeated Winning and Losing Experiences in Chronic Social Conflicts Are Linked to RNA Editing Pattern Difference
Selvaraj_2022_Comb.Chem.High.Throughput.Screen__ A comprehensive computational perspective in drug discovery for Alzheimer's disease
Semis_2022_J.Biochem.Mol.Toxicol__e23121 Protective effect of naringin against oxaliplatin-induced peripheral neuropathy in rats: A behavioral and molecular study
Singh_2022_J.Ethnopharmacol__115438 Trimethoxyflavones from Ocimum basilicum L. leaves improve long term memory in mice by modulating multiple pathways
Stazi_2022_Clin.Transl.Med_12_e651 An agonist of the CXCR4 receptor is therapeutic for the neuroparalysis induced by Bungarus snakes envenoming
Stojanovic_2022_J.Pers.Med_12_ Untangling SNP Variations within CYP2D6 Gene in Croatian Roma
Su_2022_Chem.Biol.Interact_362_109998 Structurally diverse steroids from an endophyte of Aspergillus tennesseensis 1022LEF attenuates LPS-induced inflammatory response through the cholinergic anti-inflammatory pathway
Su_2022_Exp.Gerontol__111863 Phlorizin alleviates cholinergic memory impairment and regulates gut microbiota in d-galactose induced mice
Tao_2022_Anal.Methods__ A sensitive and stable acetylcholinesterase biosensor with TiO(2) nanoparticles anchored on graphitic carbon nanofibers for determination of organophosphate pesticides
Thai_2022_J.Mol.Graph.Model_115_108230 Searching for AChE inhibitors from natural compounds by using machine learning and atomistic simulations
Worowounga_2022_Int.J.Anal.Chem_2022_4066783 Metabolites Profiling of Manilkara mabokeensis Aubrv Bark and Investigation of Biological Activities
Xu_2022_Environ.Pollut__119562 Biochemical toxicity and transcriptome aberration induced by dinotefuran in Bombyx mori
Yamahashi_2022_Mol.Psychiatry__ Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-beta-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning
Yang_2022_Evid.Based.Complement.Alternat.Med_2022_8302701 Association of the Cholinergic Anti-Inflammatory Pathway Activity with Proinflammatory Factors and Prognosis of Patients with Acute Respiratory Distress Syndrome
Yau_2022_Food.Chem_393_133383 Characterization of deglycosylated metabolites of platycosides reveals their biotransformation after oral administration
You_2022_Neurology__ Plasma-Soluble Dipeptidyl Peptidase 4 and Risk of Major Cardiovascular Events After Ischemic Stroke: Secondary Analysis of China Antihypertensive Trial in Acute Ischemic Stroke (CATIS)
Alonazi_2022_Molecules_27_ Biochemical, Kinetic and Biological Properties of Group V Phospholipase A2 from Dromedary
Amir_2022_Plants.(Basel)_11_ Roles of Syzygium in Anti-Cholinesterase, Anti-Diabetic, Anti-Inflammatory, and Antioxidant: From Alzheimer's Perspective
Andrzejewski_2022_Int.J.Mol.Sci_23_ Hypoxic and Hypercapnic Responses in Transgenic Murine Model of Alzheimer's Disease Overexpressing Human AbetaPP: The Effects of Pretreatment with Memantine and Rivastigmine
Beshana_2022_Bull.Environ.Contam.Toxicol__ Microfluidic Paper Based Analytical Devices for the Detection of Carbamate Pesticides
Cheng_2022_Molecules_27_ Phenolic Constituents, Antioxidant and Cytoprotective Activities, Enzyme Inhibition Abilities of Five Fractions from Vaccinium dunalianum Wight
Cristancho_2022_RSC.Med.Chem_13_568 Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
Fan_2022_Biomed.Environ.Sci_35_448 Association between Polymorphisms in Telomere-Associated Protein Genes and the Cholinesterase Activity of Omethoate-Exposed Workers
Feng_2022_Obstet.Gynecol.Sci_65_52 Signature of arylacetamide deacetylase expression is associated with prognosis and immune infiltration in ovarian cancer
Gao_2022_J.Mol.Graph.Model_116_108239 Molecular engineering and activity improvement of acetylcholinesterase inhibitors: Insights from 3D-QSAR, docking, and molecular dynamics simulation studies
Gladis_2022_J.Biomol.Struct.Dyn__1 Synthesis, characterisation, DNA binding, acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities and molecular docking studies of metal(II) complexes with 1,10-phenanthroline scaffold
Guajardo_2022_Methods.Mol.Biol_2487_355 Robust and Continuous Lipase-Catalyzed Reactions in Deep Eutectic Solvents: Low Viscosity and Double CLEA-LentiKats Immobilization (CLEA-LK-Lipases)
Guan_2022_Biomed.Pharmacother_152_113248 Dioscin alleviates Alzheimer's disease through regulating RAGE\/NOX4 mediated oxidative stress and inflammation
Gutowski_2022_Case.Rep.Psychiatry_2022_6966882 The Role of Acetylcholinesterase Inhibitors in the Treatment of Prolonged Postelectroconvulsive Therapy Delirium
Karcz_2022_Int.J.Mol.Sci_23_ Design, Spectroscopy, and Assessment of Cholinesterase Inhibition and Antimicrobial Activities of Novel Coumarin-Thiadiazole Hybrids
Khalid_2022_Molecules_27_ Sarcorucinine-D Inhibits Cholinesterases and Calcium Channels: Molecular Dynamics Simulation and In Vitro Mechanistic Investigations
Koszelewski_2022_Materials.(Basel)_15_ Relationship between Structure and Antibacterial Activity of alpha-Aminophosphonate Derivatives Obtained via Lipase-Catalyzed Kabachnik-Fields Reaction
Li_2022_J.Agric.Food.Chem_70_7626 Biodegradation Pathway and Detoxification of beta-cyfluthrin by the Bacterial Consortium and Its Bacterial Community Structure
Lin_2022_Nutrients_14_ The Comparative Analysis of Genomic Diversity and Genes Involved in Carbohydrate Metabolism of Eighty-Eight Bifidobacterium pseudocatenulatum Isolates from Different Niches of China
Lu_2022_Ecotoxicol.Environ.Saf_241_113738 The metabolic resistance of Nilaparvata lugens to chlorpyrifos is mainly driven by the carboxylesterase CarE17
Maciejewska_2022_Int.J.Mol.Sci_23_ Novel Cyclopentaquinoline and Acridine Analogs as Multifunctional, Potent Drug Candidates in Alzheimer's Disease
Mahmarzayeva_2022_J.Biochem.Mol.Toxicol__e23126 Oxidative brain and cerebellum injury induced by d-galactosamine: Protective effect of S-methyl methionine sulfonium chloride
Morikawa_2022_Biochem.Pharmacol_199_115010 PPARalpha regulates the expression of human arylacetamide deacetylase involved in drug hydrolysis and lipid metabolism
Morlock_2022_Molecules_27_ Effect-Directed Profiling of Monofloral Honeys from Ethiopia by High-Performance Thin-Layer Chromatography and High-Resolution Mass Spectrometry
Morte_2022_Eur.J.Drug.Metab.Pharmacokinet__ Bioavailability Study of a Transdermal Patch Formulation of Rivastigmine Compared with Exelon in Healthy Subjects
Oledzka_2022_Nutrients_14_ Potentially Bio-Accessible Metabolites from an Extract of Cornus mas Fruit after Gastrointestinal Digestion In Vitro and Gut Microbiota Ex Vivo Treatment
Pravin_2022_Int.J.Mol.Sci_23_ Effects of Linkers and Substitutions on Multitarget Directed Ligands for Alzheimer's Diseases: Emerging Paradigms and Strategies
Salah_2022_Int.J.Med.Mushrooms_24_79 Phenolic Content, Antioxidant, Antibacterial, and Anti-Acetylcholinesterase Activities of Biosynthesized and Characterized Silver Nanoparticles from Tunisian Medicinal Lichen Species
Sari_2022_Chem.Biodivers__ Antifungal azole derivatives featuring naphthalene prove potent and competitive cholinesterase inhibitors with potential CNS penetration according to the in vitro and in silico studies
Shabbir_2022_Curr.Med.Chem__ Neuroprotective potential of curcuminoids in modulating Alzheimer's Disease via multiple signaling pathways
Sole_2022_Environ.Res_213_113639 Plasmatic B-esterases as potential biomarkers of exposure to marine plastics in loggerhead turtles
Teitsdottir_2022_Front.Aging.Neurosci_14_876019 Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects
Tian_2022_Enzyme.Microb.Technol_160_110072 N-glycosylation as an effective strategy to enhance characteristics of Rhizomucor miehei lipase for biodiesel production
Turhan_2022_Chemosphere_303_135302 Developmental, toxicological effects and recovery patterns in Xenopus laevis after exposure to penconazole-based fungicide during the metamorphosis process
Tuzimski_2022_Molecules_27_3606 Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition
Udappusamy_2022_Arch.Microbiol_204_388 Lantana camara L. essential oil mediated nano-emulsion formulation for biocontrol application: anti-mosquitocidal, anti-microbial and antioxidant assay
Urban-Malinga_2022_Mar.Environ.Res_179_105660 Microplastics cause neurotoxicity and decline of enzymatic activities in important bioturbator Hediste diversicolor
Urena-Vacas_2022_Evid.Based.Complement.Alternat.Med_2022_5218248 Phytochemical Characterization and Pharmacological Properties of Lichen Extracts from Cetrarioid Clade by Multivariate Analysis and Molecular Docking
Vasdev_2022_J.Biomater.Sci.Polym.Ed__1 Rosemary oil low energy nanoemulsion: Optimization, mu-rheology, in silico, in vitro and Ex vivo characterization
Walters_2022_Res.Vet.Sci_147_44 Effects of cyclooxygenase and soluble epoxide hydrolase inhibitors on apoptosis of cultured primary equine chondrocytes
Wang_2022_Histol.Histopathol__18460 AADAC promotes therapeutic activity of cisplatin and imatinib against ovarian cancer cells
Xiao_2022_Int.Immunopharmacol_108_108741 Recombinant humanized IgG1 maintain liver triglyceride homeostasis through Arylacetamide deacetylase in ApoE(-\/-) mice
Xu_2022_Molecules_27_3475 Rapid Screening of Lipase Inhibitors in Scutellaria baicalensis by Using Porcine Pancreatic Lipase Immobilized on Magnetic Core-Shell Metal-Organic Frameworks
Yang_2022_Food.Chem_393_133349 Acidic pH and thiol-driven homogeneous cathodic electrochemiluminescence strategy for determining the residue of organophosphorus pesticide in Chinese cabbage
Yang_2022_Ecotoxicol.Environ.Saf_241_113756 Transcriptomic responses of the zearalenone (ZEN)-detoxifying yeast Apiotrichum mycotoxinivorans to ZEN exposure
Yu_2022_PLoS.Pathog_18_e1010552 Lipases secreted by a gut bacterium inhibit arbovirus transmission in mosquitoes
Zare_2022_Neurosci__ Neuroprotective effects of treadmill exercise in hippocampus of ovariectomized and diabetic rats
Zhang_2022_J.Affect.Disord__ Prolonged sevoflurane exposure causes abnormal synapse development and dysregulates beta-neurexin and neuroligins in the hippocampus in neonatal rats
Zhang_2022_Talanta_249_123664 CoOOH nanosheets ensure ratiometric fluorescence assay of acetylcholinesterase
Ahmad_2022_CNS.Neurol.Disord.Drug.Targets_21_610 Strategic Approaches to Target the Enzymes using Natural Compounds for the Management of Alzheimer's Disease: A Review
Ahmadi_2022_Pestic.Biochem.Physiol_184_105115 Biochemical and insecticidal effects of plant essential oils on insecticide resistant and susceptible populations of Musca domestica L. point to a potential cross-resistance risk
Alimi_2022_Vet.Parasitol_309_109743 Acaricidal and anthelmintic efficacy of Ocimum basilicum essential oil and its major constituents estragole and linalool, with insights on acetylcholinesterase inhibition
Anita_2022_Int.J.Mol.Sci_23_ Soluble Epoxide Hydrolase and Diabetes Complications
Barchuk_2022_Arterioscler.Thromb.Vasc.Biol__101161ATVBAHA122317840 Epicardial Adipose Tissue Ceramides Are Related to Lipoprotein Lipase Activity in Coronary Artery Disease: Unfolding a Missing Link
Brandenberg_2022_Microb.Cell.Fact_21_119 Towards synthetic PETtrophy: Engineering Pseudomonas putida for concurrent polyethylene terephthalate (PET) monomer metabolism and PET hydrolase expression
Brinkley_2022_Front.Neurosci_16_906539 Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer's Disease
Chen_2022_J.Food.Sci__ Ferulic acid- and gallic ester-acylated pectin: Preparation and characterization
Curtis_2022_Environ.Health.Perspect_130_68003 Comment on Evaluation of a Gene-Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case-Control Study Drawn from the U.S. Military Health Survey's National Population Sample
Devi_2022_Pestic.Biochem.Physiol_184_105116 A novel biofumigant from Tithonia diversifolia (Hemsl.) A. Gray for control of stored grain insect pests
Ganeshpurkar_2022_Future.Med.Chem__ Identification of sulfonamide-based butyrylcholinesterase inhibitors using machine learning
Gautam_2022_Environ.Res__113689 Soil degradation kinetics of oxybenzone (Benzophenone-3) and toxicopathological assessment in the earthworm, Eisenia fetida
Gomez-Garcia_2022_Front.Neurol_13_909715 Case Report: A Novel AChR Epsilon Variant Causing a Clinically Discordant Salbutamol Responsive Congenital Myasthenic Syndrome in Two Egyptian Siblings
Gupta_2022_Cureus_14_e25005 Alzheimer's Disease and Stroke: A Tangled Neurological Conundrum
Haley_2022_Environ.Health.Perspect_130_68004 Response to Comment on 'Evaluation of a Gene-Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case-Control Study Drawn from the U.S. Military Health Survey's National Population Sample'
Halff_2022_Sci.Signal_15_eabg2505 Phosphorylation of neuroligin-2 by PKA regulates its cell surface abundance and synaptic stabilization
Han_2022_Am.J.Infect.Control__ Risk factors for hospital-acquired pneumonia among inpatients with mental disorders in a large mental health center within a tertiary general hospital
Han_2022_Sci.Adv_8_eabo4173 Neuroligin-3 confines AMPA receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses
Kassay_2022_PLoS.One_17_e0269936 Cigarette smoke toxin hydroquinone and misfolding pancreatic lipase variant cooperatively promote endoplasmic reticulum stress and cell death
Khalifa_2022_Inflammopharmacology__ Phosphodiesterase (PDE) III inhibitor, Cilostazol, improved memory impairment in aluminum chloride-treated rats: modulation of cAMP\/CREB pathway
Lal_2022_Sci.Rep_12_9978 Anethole rich Clausena heptaphylla (Roxb.) Wight & Arn., essential oil pharmacology and genotoxic efficiencies
Li_2022_Zhongguo.Zhong.Yao.Za.Zhi_47_2759 [Mechanism of Shenxiong Glucose Injection against myocardial ischemia-reperfusion injury based on network pharmacology and molecular docking]
Li_2022_J.Ethnopharmacol__115460 Anti-Alzheimer's disease active components screened out and identified from Hedyotis diffusa combining bioaffinity ultrafiltration LC-MS with acetylcholinesterase
Liu_2022_Rapid.Commun.Mass.Spectrom__e9332 Detoxification mechanism of vinegar-processed Kansui revealed by systematic phytochemical analysis using UPLC-DAD-MS\/MS, UPLC-HR-MS and in silico drug target identification
Lu_2022_Chirality__ The optimized biocatalytic synthesis of (S)-methyl 2-chlorobutanoate by Acinetobacter sp. lipase
Manuel_2022_Environ.Res__113584 Effects of nanoplastics on zebrafish embryo-larval stages: A case study with polystyrene (PS) and polymethylmethacrylate (PMMA) particles
Martins_2022_Biotechnol.Lett__ Solvent screening, optimization and kinetic parameters of the biocatalytic epoxidation reaction of beta-pinene mediated by Novozym435
McClelland_2022_Environ.Sci.Technol__ Developmental Exposure to Trace Concentrations of Chlorpyrifos Results in Nonmonotonic Changes in Brain Shape and Behavior in Amphibians
Missaglia_2022_Eur.J.Transl.Myol__ Neutral lipid storage disease with myopathy: A 10-year follow-up case report
Nishal_2022_CNS.Neurol.Disord.Drug.Targets__ A concise review of common plant-derived compounds as potential therapy for Alzheimer's disease and Parkinson's disease: Insight into Structure-Activity-Relationship
Parama_2022_Pharmacol.Res_179_106202 An overview of the pharmacological activities of scopoletin against different chronic diseases
Puopolo_2022_Med.Cannabis.Cannabinoids_5_85 Inhibitory Effects of Cannabinoids on Acetylcholinesterase and Butyrylcholinesterase Enzyme Activities
Ramasamy_2022_Environ.Sci.Pollut.Res.Int__ Enzyme hydrolysis of polyester knitted fabric: A method to control the microfiber shedding from synthetic textile
Roberts_2022_Front.Immunol_13_893844 Differential Regulation of Allergic Airway Inflammation by Acetylcholine
Rose_2022_Front.Behav.Neurosci_16_908630 Neuroligin Plays a Role in Ethanol-Induced Disruption of Memory and Corresponding Modulation of Glutamate Receptor Expression
Samareh_2022_Toxicol.Ind.Health__7482337221106754 Occupational exposure to pesticides in farmworkers and the oxidative markers
Sharif_2022_Sci.Rep_12_10405 Silencing of multiple target genes via ingestion of dsRNA and PMRi affects development and survival in Helicoverpa armigera
Siraliev-Perez_2022_Elife_11_ Dynamics of allosteric regulation of the phospholipase C-gamma isozymes upon recruitment to membranes
Skaggs_2022_J.Mass.Spectrom.Adv.Clin.Lab__ Development and Validation of a Paper Spray Mass Spectrometry Method for the Rapid Quantitation of Remdesivir and its Active Metabolite, GS-441524, in Human Plasma
Song_2022_Nat.Prod.Res__1 One new furanone analogue from the deep-sea fungus Purpureocillium sp. SCSIO 06693
Telahigue_2022_Pestic.Biochem.Physiol_184_105099 Glyphosate exposure modulates lipid composition, histo-architecture and oxidative stress status and induces neurotoxicity in the smooth scallop Flexopecten glaber
Vivek_2022_Biotechnol.Adv_60_108002 Extremophilic lipases for industrial applications: A general review
Wagner_2022_Cell.Rep_39_110923 Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target
Wang_2022_Phytochemistry__113279 Isosteroidal alkaloids of Fritillaria taipaiensis and their implication to Alzheimer's disease: Isolation, structural elucidation and biological activity
Wang_2022_Mol.Neurodegener_17_42 Calcium-dependent cytosolic phospholipase A(2) activation is implicated in neuroinflammation and oxidative stress associated with ApoE4
Weisskopf_2022_Environ.Health.Perspect_130_68005 Response to Comment on 'Evaluation of a Gene-Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case-Control Study Drawn from the U.S. Military Health Survey's National Population Sample'
Xie_2022_Crit.Rev.Food.Sci.Nutr__1 Progress in enrichment of n-3 polyunsaturated fatty acid: a review
Yang_2022_J.Environ.Sci.(China)_117_129 Neurotoxicity and transcriptome changes in embryonic zebrafish induced by halobenzoquinone exposure
Yu_2022_J.Dairy.Sci__ Activated autophagy-lysosomal pathway in dairy cows with hyperketonemia is associated with lipolysis of adipose tissues
Zacchaeus_2022_Anticancer.Agents.Med.Chem__ New neo-Clerodane diterpenoids isolated from Ajuga decumbens Thunb., planted in Pingtan island of Fujian Province with the potent anticancer activity
Al-Joufi_2022_Brain.Sci_12_ Flavonoid Derivatives as Potential Cholinesterase Inhibitors in Scopolamine-Induced Amnesic Mice: An In Vitro, In Vivo and Integrated Computational Approach
Areche_2022_Metabolites_12_ UHPLC-MS Metabolomic Fingerprinting, Antioxidant, and Enzyme Inhibition Activities of Himantormia lugubris from Antarctica
Asen_2022_J.Food.Biochem__e14289 Acetylcholinesterase and butyrylcholinesterase inhibitory activities of antioxidant peptides obtained from enzymatic pea protein hydrolysates and their ultrafiltration peptide fractions
Bilal_2022_RSC.Adv_12_16860 A novel construct of an electrochemical acetylcholinesterase biosensor for the investigation of malathion sensitivity to three different insect species using a NiCr(2)O(4)\/g-C(3)N(4) composite integrated pencil graphite electrode
Borgo_2022_Nat.Commun_13_3656 A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes
Bortolami_2022_Pharmaceuticals.(Basel)_15_ Design, Synthesis, and In Vitro, In Silico and In Cellulo Evaluation of New Pyrimidine and Pyridine Amide and Carbamate Derivatives as Multi-Functional Cholinesterase Inhibitors
Boukadida_2022_Mar.Environ.Res_179_105677 Metal contamination and heat stress impair swimming behavior and acetylcholinesterase activity in embryo-larval stages of the Mediterranean mussel, Mytilus galloprovincialis
Budryn_2022_Nutrients_14_ Hydroxybenzoic Acids as Acetylcholinesterase Inhibitors: Calorimetric and Docking Simulation Studies
Burgess_2022_PLoS.One_17_e0268205 Assessing pyrethroid resistance status in the Culex pipiens complex (Diptera: Culicidae) from the northwest suburbs of Chicago, Illinois using Cox regression of bottle bioassays and other detection tools
Deng_2022_Addict.Biol_27_e13179 Recovery of dopaminergic system after cocaine exposure and impact of a long-acting cocaine hydrolase
Eissa_2022_Drug.Dev.Res__ Design, synthesis, and biological evaluation of thienopyrimidine and thienotriazine derivatives as multitarget anti-Alzheimer agents
Eroglu_2022_Front.Pharmacol_13_923063 The Therapeutic Potential of Ethnomedicinally Important Anatolian Thyme Species: A Phytochemical and Biological Assessment
Fugazzotto_2022_Rev.Bras.Med.Vet_44_e003921 Clinical and diagnostic imaging findings in a bengal tiger (Panthera tigris tigris) with cervical spondylomyelopathy: A case report
Gao_2022_Comput.Struct.Biotechnol.J_20_2815 Role of Bmal1 in mediating the cholinergic system to regulate the behavioral rhythm of nocturnal marine molluscs
Gazzillo_2022_Molecules_27_ Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation
Guedegba_2022_Chemosphere_305_135407 Integrated biomarker response to assess the effects of pesticide residues on Nile Tilapia in aquatic ecosystems contaminated by cotton-field effluents
Hao_2022_Front.Pharmacol_13_917375 Neuroprotective Effect and Possible Mechanisms of Berberine in Diabetes-Related Cognitive Impairment: A Systematic Review and Meta-Analysis of Animal Studies
Hussein_2022_Exp.Neurol_355_114145 Cognitive deficits and altered cholinergic innervation in young adult male mice carrying a Parkinson's disease Lrrk2(G2019S) knockin mutation
Jaramillo_2022_Molecules_27_ Chemical Characterization and Biological Activity of the Essential Oil from Araucaria brasiliensis Collected in Ecuador
Khalil_2022_Neurotoxicol__ Selenium nanoparticles impart robust neuroprotection against deltamethrin-induced neurotoxicity in male rats by reversing behavioral alterations, oxidative damage, apoptosis, and neuronal loss
Komatovic_2022_Pharmaceutics_14_ 4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer's Disease
Li_2022_Cells_11_ Modulation of Trans-Synaptic Neurexin-Neuroligin Interaction in Pathological Pain
Li_2022_J.Neuroinflammation_19_131 Interleukin-6 and YKL-40 predicted recurrent stroke after ischemic stroke or TIA: analysis of 6 inflammation biomarkers in a prospective cohort study
Li_2022_Food.Res.Int_157_111243 Effect of industrial processing on the volatiles, enzymes and lipids of wholegrain and rolled oats
Liu_2022_Methods.Mol.Biol_2492_117 A Three-Dimensional Brain-on-a-Chip Using Human iPSC-Derived GABAergic Neurons and Astrocytes
Luduvico_2022_Metab.Brain.Dis__ LPS-induced impairment of Na(+)\/K(+)-ATPase activity: ameliorative effect of tannic acid in mice
Mamadalieva_2022_Life.(Basel)_12_ Ecdysteroids as Potent Enzyme Inhibitors and Verification of Their Activity Using In Vitro and In Silico Docking Studies
Mavroidi_2022_Brain.Sci_12_ The Prophylactic and Multimodal Activity of Two Isatin Thiosemicarbazones against Alzheimer's Disease In Vitro
Mu_2022_Food.Chem_394_133517 Branched poly(ethylenimine) carbon dots-MnO(2) nanosheets based fluorescent sensory system for sensing of malachite green in fish samples
Muir_2022_ACS.Chem.Biol_17_281 Activity-Based Diagnostics: Recent Advances in the Development of Probes for Use with Diverse Detection Modalities
Nagel_2022_Environ.Sci.Pollut.Res.Int__ Effect of thallium on phototactic behaviour in Daphnia magna
Nguyen_2022_ACS.Omega_7_20673 Identifying Possible AChE Inhibitors from Drug-like Molecules via Machine Learning and Experimental Studies
Ortega_2022_Int.J.Mol.Sci_23_ Kinetic Modeling, Thermodynamic Approach and Molecular Dynamics Simulation of Thermal Inactivation of Lipases from Burkholderia cepacia and Rhizomucor miehei
Pandey_2022_iScience_25_104543 Model scenarios for cell cycle re-entry in Alzheimer's disease
Ramazani_2022_Life.Sci__120728 Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms
Rana_2022_Inorg.Chem__ Azo-Stilbene and Pyridine-Amine Hybrid Multifunctional Molecules to Target Metal-Mediated Neurotoxicity and Amyloid-beta Aggregation in Alzheimer's Disease
Sakthivel_2022_ACS.Omega_7_20515 Potential Acetylcholinesterase Inhibitor Acting on the Pesticide Resistant and Susceptible Cotton Pests
Satoh_2022_J.Clin.Med_11_ Effects of Smart Drugs on Cholinergic System and Non-Neuronal Acetylcholine in the Mouse Hippocampus: Histopathological Approach
Senarathne_2022_J.Environ.Public.Health_2022_7826396 Selected Liver Markers in Predicting the Severity of Organophosphate and Carbamate Poisoning
Shigemizu_2022_Am.J.Med.Genet.B.Neuropsychiatr.Genet__ Network-based meta-analysis and the candidate gene association studies reveal novel ethnicity-specific variants in MFSD3 and MRPL43 associated with dementia with Lewy bodies
Sun_2022_Front.Mol.Neurosci_15_901953 Eucommia ulmoides Olive Male Flower Extracts Ameliorate Alzheimer's Disease-Like Pathology in Zebrafish via Regulating Autophagy, Acetylcholinesterase, and the Dopamine Transporter
Tariq_2022_Chem.Biodivers__ Synthesis, in vitro cholinesterase inhibition, molecular docking, DFT and ADME studies of novel 1,3,4-oxadiazole 2-thiol derivatives
Temporiti_2022_Microorganisms_10_ Fungal Enzymes Involved in Plastics Biodegradation
Tok_2022_Chem.Biodivers__ N-Substituted arylidene-3-(methylsulfonyl)-2-oxoimidazolidine-1-carbohydrazide as cholinesterase inhibitors: Design, synthesis, and molecular docking study
Tosi_2022_Sci.Total.Environ__156857 Lethal, sublethal, and combined effects of pesticides on bees: A meta-analysis and new risk assessment tools
Trigui_2022_Environ.Sci.Pollut.Res.Int__ Mitigation of OMW toxicity toward Enchytraeus albidus with application of additives
Wan_2022_Environ.Epigenet_8_dvac013 Assessment of parental benzo[a]pyrene exposure-induced cross-generational neurotoxicity and changes in offspring sperm DNA methylome in medaka fish
Wang_2022_Sci.Rep_12_10979 Retrospective detection for V-type OPNAs exposure via phosphonylation and disulfide adducts in albumin
Zhang_2022_Int.J.Mol.Sci_23_6871 Diterpenoid Caesalmin C Delays Abeta-Induced Paralysis Symptoms via the DAF-16 Pathway in Caenorhabditis elegans
Zheng_2022_Bioconjug.Chem__ Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism
Zou_2022_Cell.Biosci_12_93 Post-synaptic specialization of the neuromuscular junction: junctional folds formation, function, and disorders
Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330 Evaluating the neuroprotective activities of vinpocetine, punicalagin, niacin and vitamin E against behavioural and motor disabilities of manganese-induced Parkinson's disease in Sprague Dawley rats
Afsar_2022_BMC.Complement.Med.Ther_22_179 Reversal of cisplatin triggered neurotoxicity by Acacia hydaspica ethyl acetate fraction via regulating brain acetylcholinesterase activity, DNA damage, and pro-inflammatory cytokines in the rodent model
Arruda-Junior_2022_Life.Sci__120757 Unraveling the interplay between dipeptidyl peptidase 4 and the renin-angiotensin system in heart failure
Benito-Murcia_2022_Environ.Toxicol.Pharmacol__103920 Evaluating the chronic effect of two varroacides using multiple biomarkers and an integrated biological response index
Bernstein_2022_Rev.Neurosci__ The many facets of CD26\/dipeptidyl peptidase 4 and its inhibitors in disorders of the CNS - a critical overview
Charles_2022_Cells_11_ Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease
Corvillo_2022_Diabetes__ Characterization and Clinical Association of Autoantibodies Against Perilipin 1 in Patients with Acquired Generalized Lipodystrophy
De Felice_2022_Sci.Total.Environ__157025 Differential biochemical and behavioral responses induced by cocaine and benzoylecgonine exposure to the red swamp crayfish Procambarus clarkii
Fujino_2022_Biochem.Biophys.Res.Commun_620_15 Limited effects of systemic or renal lipoprotein lipase deficiency on renal physiology and diseases
Garcia-Rates_2022_Int.J.Biochem.Cell.Biol__106260 WHEN A TROPHIC PROCESS TURNS TOXIC: ALZHEIMER'S DISEASE AS AN ABERRANT RECAPITULATION OF A DEVELOPMENTAL MECHANISM
Giangeri_2022_Sci.Total.Environ__157017 Preliminary investigation of microorganisms potentially involved in microplastics degradation using an integrated metagenomic and biochemical approach
Guo_2022_Pestic.Biochem.Physiol_185_105136 Enantioselective neurotoxicity and oxidative stress effects of paclobutrazol in zebrafish (Danio rerio)
Han_2022_Bioorg.Med.Chem.Lett__128873 Design, synthesis and evaluation of 2-(2-oxoethyl)pyrimidine-5-carboxamide derivatives as acetylcholinesterase inhibitors
Hemmersbach_2022_Chemistry__ Synthesis and Biological Evaluation of Water-Soluble Esterase-Activated CO-Releasing Molecules Targeting Mitochondria
Hotta_2022_Br.J.Radiol__20220463 Non-oncologic incidental uptake on FAPI PET\/CT imaging
Kaur_2022_Mini.Rev.Med.Chem__ Alzheimer's Disease: Treatment of Multi-Factorial Disorders with Multi-Target Approach
Khruengsai_2022_Front.Microbiol_13_874842 Biodegradation of Polyester Polyurethane by Embarria clematidis
Kumar_2022_Cell.Biochem.Funct__ Dental pulp stem cell secretome ameliorates d-galactose induced accelerated aging in rat model
Li_2022_Pestic.Biochem.Physiol_185_105150 Differences in susceptibility to chlorantraniliprole between Chilo suppressalis (Lepidoptera: Crambidae) and two dominant parasitic wasps collected from Sichuan Province, China
Malta_2022_Sci.Rep_12_11065 Identification of bioactive peptides from a Brazilian kefir sample, and their anti-Alzheimer potential in Drosophila melanogaster
Mattar_2022_Pestic.Biochem.Physiol_185_105134 Insecticidal activity of the essential oil of Schinus areira against Rhipibruchus picturatus (F.) (Coleoptera: Bruchinae), and its inhibitory effects on acetylcholinesterase
Medithi_2022_Front.Public.Health_10_872125 Impact of Micronutrient Supplementation on Pesticide Residual, Acetylcholinesterase Activity, and Oxidative Stress Among Farm Children Exposed to Pesticides
Mi_2022_J.Hazard.Mater_438_129419 Ternary heterostructures of 1D\/2D\/2D CuCo(2)S(4)\/CuS\/Ti(3)C(2) MXene: Boosted amperometric sensing for chlorpyrifos
Murshed_2022_Int.J.Pharm_623_121958 Controlling drug release by introducing lipase inhibitor within a lipid formulation
Narvaez_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109404 Synergistic effects of pesticides and environmental variables on earthworm standard metabolic rate
Novales_2022_Anal.Biochem__114796 Comparing the effects of organic cosolvents on acetylcholinesterase and butyrylcholinesterase activity
Ozturk_2022_Mol.Divers__ Synthesis of novel carboxamide- and carbohydrazide-benzimidazoles as selective butyrylcholinesterase inhibitors
Perrin_2022_Pestic.Biochem.Physiol_185_105139 Cross effects of heat stress and three insecticides on the survival of the codling moth Cydia pomonella (L.): Investigating the molecular and biochemical mechanisms
Pour_2022_Pestic.Biochem.Physiol_185_105135 Toxicity, antifeedant and physiological effects of trans-anethole against Hyphantria cunea Drury (Lep: Arctiidae)
Sanchez-Martinez_2022_Front.Nutr_9_924596 Blood-Brain Barrier Permeability Study of Potential Neuroprotective Compounds Recovered From Plants and Agri-Food by-Products
Sato_2022_J.Toxicol.Sci_47_277 Assessment of metabolic activation of felbamate in chimeric mice with humanized liver in combination with in vitro metabolic assays
Soderlund_2022_Biotechnol.Lett__ Facile synthesis of 2-hydroxyacetophenone from racemic styrene oxide catalyzed by engineered enzymes
Taktak_2022_Pestic.Biochem.Physiol_185_105151 Nanoemulsions containing some plant essential oils as promising formulations against Culex pipiens (L.) larvae and their biochemical studies
Tan_2022_J.Pharm.Biomed.Anal_219_114897 Simultaneous screening, identification, quantitation, and activity evaluation of six acetylcholinesterase (AChE) inhibitors in Coptidis Rhizoma by online UPLC-DAD coupled with AChE biochemical detection
Thomson_2022_J.Vet.Diagn.Invest__10406387221106401 Retrospective analysis of association between hepatopathy and serum DGGR lipase activity in dogs: a pilot study
Tonietto_2022_Environ.Toxicol.Pharmacol__103924 Imidacloprid-based commercial pesticide causes behavioral, biochemical, and hematological impairments in Wistar rats
Torres-Banda_2022_Comput.Struct.Biotechnol.J_20_3080 Gut transcriptome of two bark beetle species stimulated with the same kairomones reveals molecular differences in detoxification pathways
Vega-Rodriguez_2022_Chembiochem__ Feruloyl esterases protein engineering to enhance their performance as biocatalysts: a review
Velueta-Viveros_2022_Bioorg.Chem_127_105983 Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases\/OGA) against Alzheimer's disease
Wagmann_2022_Arch.Toxicol__ Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterases
Wang_2022_Sci.Total.Environ__156936 Study on the toxic-mechanism of triclosan chronic exposure to zebrafish (Danio rerio) based on gut-brain axis
Wang_2022_Front.Physiol_13_879216 Physiological Responses of the Firefly Pyrocoelia analis (Coleoptera: Lampyridae) to an Environmental Residue From Chemical Pesticide Imidacloprid
Wu_2022_Biomed.Pharmacother_153_113339 A narrative review: The pharmaceutical evolution of phenolic syringaldehyde
Xenoulis_2022_J.Feline.Med.Surg_24_651 Feline Comorbidities: Clinical perspective on diabetes mellitus and pancreatitis
Xie_2022_Front.Nutr_9_929343 Effects of Flavonoid Supplementation on Nanomaterial-Induced Toxicity: A Meta-Analysis of Preclinical Animal Studies
Yilmaz_2022_Eur.Rev.Med.Pharmacol.Sci_26_4409 Effects of an acetylcholinesterase inhibitor and an N-methyl-D-aspartate receptor antagonist on inflammation and degeneration of the nucleus pulposus
Zhang_2022_Food.Chem_395_133547 Modulation of oxidative stress and gut microbiota by selenium-containing peptides from Cardamine enshiensis and structural-based characterization
Ahmad_2022_Cell.Mol.Biol.(Noisy-le-grand)_67_106 Emetine and Indirubin- 3- monoxime interaction with human brain acetylcholinesterase: A computational and statistical analysis
Alarcon-Enos_2022_J.Enzyme.Inhib.Med.Chem_37_1845 Dyhidro-beta-agarofurans natural and synthetic as acetylcholinesterase and COX inhibitors: interaction with the peripheral anionic site (AChE-PAS), and anti-inflammatory potentials
Ali_2022_PLoS.One_17_e0271138 Effects of antidiabetic agents on Alzheimer's disease biomarkers in experimentally induced hyperglycemic rat model by streptozocin
Berger_2022_Int.J.Mol.Sci_23_ Serine Hydrolases in Lipid Homeostasis of the Placenta-Targets for Placental Function?
Chea_2022_Molecules_27_ Microwave-Assisted Synthesis of 5'-O-methacryloylcytidine Using the Immobilized Lipase Novozym 435
Cormier_2022_Environ.Pollut_308_119721 Environmental microplastics disrupt swimming activity in acute exposure in Danio rerio larvae and reduce growth and reproduction success in chronic exposure in D. rerio and Oryzias melastigma
da Conceicao Filho_2022_Ir.J.Med.Sci__ Black and non-black population: investigation of the difference in butyrylcholinesterase activity in a healthy population in Salvador, Bahia
Ding_2022_Chin.J.Integr.Med__ Echinacoside Alleviates Cognitive Impairment in Cerebral Ischemia Rats through alpha 7nAChR-Induced Autophagy
Dong_2022_Int.J.Mol.Sci_23_ Investigation of Structural Features of Two Related Lipases and the Impact on Fatty Acid Specificity in Vegetable Fats
Elumalai_2022_Org.Biomol.Chem__ Development of potent cholinesterase inhibitors based on a marine pharmacophore
Gao_2022_Nat.Metab__ Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol
Grigorev_2022_J.Mol.Graph.Model_116_108265 Structural fractal analysis of the active sites of acetylcholinesterase from various organisms
Han_2022_J.Clin.Neurol_18_428 A Multinational, Multicenter, Randomized, Double-Blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer's Disease
Iqbal_2022_Molecules_27_ Extraction and Fractionation of Prokinetic Phytochemicals from Chrozophora tinctoria and Their Bioactivities
Kerckhove_2022_BMC.Cancer_22_742 Efficacy of donepezil for the treatment of oxaliplatin-induced peripheral neuropathy: DONEPEZOX, a protocol of a proof of concept, randomised, triple-blinded and multicentre trial
Kumar_2022_ACS.Chem.Neurosci__ Design, Synthesis, and Pharmacological Evaluation of N-Propargylated Diphenylpyrimidines as Multitarget Directed Ligands for the Treatment of Alzheimer's Disease
Lim_2022_Molecules_27_ The Attenuating Effect of Beta-Carotene on Streptozotocin Induced Diabetic Vascular Dementia Symptoms in Rats
Liu_2022_Environ.Sci.Pollut.Res.Int_29_85482 Effects and mechanism of ultrasound treatment on Chironomus kiiensis eggs
Liu_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_260_109406 The physiological, biochemical and transcriptional responses to sulfamethoxazole in the Asian clam, Corbicula fluminea (O. F. Muller, 1774)
Mabrouk_2022_Environ.Sci.Pollut.Res.Int__ Topiramate potential neurotoxicity and mitigating role of ginger oil in mice brain
Maksimovic_2022_Acta.Medica.(Hradec.Kralove)_65_8 Dose-Dependency of Toxic Signs and Outcomes of Paraoxon Poisoning in Rats
Mani_2022_Saudi.Pharm.J_30_750 Sukkari dates seed improves type-2 diabetes mellitus-induced memory impairment by reducing blood glucose levels and enhancing brain cholinergic transmission: In vivo and molecular modeling studies
Micinski_2022_Animals.(Basel)_12_ Uterine Inflammation Changes the Expression of Cholinergic Neurotransmitters and Decreases the Population of AChE-Positive, Uterus-Innervating Neurons in the Paracervical Ganglion of Sexually Mature Gilts
Minamizuka_2022_Clin.Biochem__ Homozygous familial lipoprotein lipase deficiency without obvious coronary artery stenosis
Muller_2022_Appl.Microbiol.Biotechnol_106_4481 Accelerated strain construction and characterization of C. glutamicum protein secretion by laboratory automation
Ogunsuyi_2022_J.Food.Biochem__e14312 Effect of chlorogenic acid plus donepezil on critical neurocortical enzyme activities, inflammatory markers, and synaptophysin immunoreactivity in scopolamine-assaulted rats, supported by multiple ligand simultaneous docking
Ozaslan_2022_Chem.Biodivers__e202200280 Isolation of Some Phenolic Compounds from Plantago subulata L. and Determination of Their Antidiabetic, Anticholinesterase, Antiepileptic and Antioxidant Activity
Purgatorio_2022_Molecules_27_ Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases
Rump_2022_PLoS.One_17_e0271119 Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium?
Shu_2022_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_281_121529 A hemicyanine-based fluorescent probe for simultaneous imaging of Carboxylesterases and Histone deacetylases in hepatocellular carcinoma
Silva_2022_Environ.Res__113764 Does parental exposure to nanoplastics modulate the response of Hediste diversicolor to other contaminants: A case study with arsenic
Tao_2022_JCI.Insight_7_ Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells
Tian_2022_Bioorg.Chem_127_105898 Discovery of benzamide derivatives containing urea moiety as soluble epoxide hydrolase inhibitors
Trombini_2022_Ecotoxicol.Environ.Saf_242_113845 Bioaccumulation and biochemical responses in the peppery furrow shell Scrobicularia plana exposed to a pharmaceutical cocktail at sub-lethal concentrations
Wang_2022_Foods_11_1954 Whole-Genome Sequencing of a Potential Ester-Synthesizing Bacterium Isolated from Fermented Golden Pomfret and Identification of Its Lipase Encoding Genes
Wang_2022_Ecotoxicol.Environ.Saf_242_113870 Isoprocarb causes neurotoxicity of zebrafish embryos through oxidative stress-induced apoptosis
Wang_2022_Molecules_27_ Role of Natural Compounds and Target Enzymes in the Treatment of Alzheimer's Disease
Wang_2022_Front.Nutr_9_861097 Evaluation of Antioxidative and Neuroprotective Activities of Total Flavonoids From Sea Buckthorn (Hippophae rhamnoides L.)
Whitfield_2022_Twin.Res.Hum.Genet__1 Co-Inheritance of Variation in All-Cause Mortality and Biochemical Risk Factors
Xianchu_2022_Pak.J.Pharm.Sci_35_769 Protective effect of rutin against diabetes-associated cognitive decline in rats
Xiang_2022_J.Hazard.Mater_438_129454 Microplastics exposure as an emerging threat to ancient lineage: A contaminant of concern for abnormal bending of amphioxus via neurotoxicity
Yadav_2022_Int.J.Mol.Sci_23_ Anti-adipogenic and Pro-lipolytic Effects on 3T3-L1 Preadipocytes by CX-4945, an Inhibitor of Casein Kinase 2
Ye_2022_Nanomedicine__102581 Esterase-responsive and size-optimized prodrug nanoparticles for effective intracranial drug delivery and glioblastoma treatment
You-Gui_2022_Cell.Mol.Biol.(Noisy-le-grand)_67_232 The relationship of hs-CRP, vitronectin and NT-proBNP serum levels with the extent and severity of cardiac complications in patients with organophosphate pesticide poisoning
Zhao_2022_J.Sep.Sci__ Screening of acetylcholinesterase inhibitory and antioxidant active compounds from Terminalia chebula fruits by spectrum-effect relationship and liquid chromatography-mass spectrometry analysis
Zhou_2022_Aging.Clin.Exp.Res__ Effect of transcutaneous auricular vagus nerve stimulation on delayed neurocognitive recovery in elderly patients
Zifu_2022_Cell.Mol.Biol.(Noisy-le-grand)_67_121 Effect of Qingre Jiedu Huoxue Huayu Recipe on blood stasis and toxin syndrome in patients with non-ST segment elevation acute coronary syndrome, serum Lp-PLA2, TNF- alpha, and PIGF expression level
Martelli_2022_Bioorg.Chem_120_105580 Chemoenzymatic enantioselective route to get (+) and (-) 4-acetoxy-azetidin-2-one by lipase-catalysed kinetic resolution and their applications
Cho_2022_Biochemistry_61_183 Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N-Methyltransferases in Bacteria
Sarkar_2022_ACS.Chem.Biol__ Applying Promiscuous RiPP Enzymes to Peptide Backbone N-Methylation Chemistry
Xu_2022_Mol.Cell.Endocrinol_544_111555 Pharmacological agents targeting autophagy and their effects on lipolysis in human adipocytes
Zhang_2022_Pharm.Res_39_75 Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases
Abohalaka_2022_Life.Sci__120808 Endocannabinoid metabolism inhibition ameliorates ovalbumin-induced allergic airway inflammation and hyperreactivity in Guinea pigs
Ahadji-Dabla_2022_Heliyon_8_e09770 Resistance intensity status of Anopheles gambiae s.l. species at KOLOKOPE, eastern plateau Togo: A potential site to assess new vector control tools
Amaral_2022_Ecotoxicol.Environ.Saf_242_113831 Fitness cost and reversion of resistance Leucoptera coffeella (Lepidoptera: Lyonetiidae) to chlorpyrifos
Anstey_2022_Mol.Autism_13_34 Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3(-\/y) rat model of autism
Asamba_2022_Heliyon_8_e09176 Molecular characterization of chlorpyrifos degrading bacteria isolated from contaminated dairy farm soils in Nakuru County, Kenya
Basaran_2022_J.Mol.Recognit__e2982 Biological activity and molecular docking studies of some N-phenylsulfonamides against cholinesterases and carbonic anhydrase isoenzymes
Basso_2022_J.Environ.Sci.Health.B__1 The integrated biomarker response in three anuran species larvae at sublethal concentrations of cypermethrin, chlorpyrifos, glyphosate, and glufosinate-ammonium
Beltran_2022_Nat.Biotechnol__ Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds
Choi_2022_Mol.Brain_15_63 Donepezil ameliorates Abeta pathology but not tau pathology in 5xFAD mice
Contreras-Aguilar_2022_BMC.Vet.Res_18_275 Changes in salivary analytes in cows due to the in vitro presence of feed
Dar_2022_Arch.Microbiol_204_482 Biodegradation of malathion by Micrococcus sp. strain MAGK3: kinetics and degradation fragments
de Oliveira_2022_Int.J.Dev.Neurosci__ Perinatal exposure to glyphosate-based herbicides induced neurodevelopmental behaviors impairments and increased oxidative stress in the prefrontal cortex and hippocampus in offspring
Durner_2022_EBioMedicine_82_104172 Letter to Butyrylcholinesterase is a potential biomarker for Sudden Infant Death Syndrome
Fan_2022_Chemosphere__135670 Accumulation and translocation of traditional and novel organophosphate esters and phthalic acid esters in plants during the whole life cycle
Gautam_2022_SAGE.Open.Med.Case.Rep_10_2050313X221104309 Delayed myelopathy after organophosphate intoxication: A case report
Harrington_2022_EBioMedicine_82_104171 Letter Re: Butyrylcholinesterase is a potential biomarker for sudden infant death syndrome
Hu_2022_Appl.Biochem.Biotechnol__ Immobilization for Lipase: Enhanced Activity and Stability by Flexible Combination and Solid Support
Hussain_2022_Am.J.Transl.Res_14_3824 In vitro and in vivo study of inhibitory potentials of alpha-glucosidase and acetylcholinesterase and biochemical profiling of M. charantia in alloxan-induced diabetic rat models
Jakubowska-Lehrmann_2022_Mar.Environ.Res_179_105700 Do magnetic fields related to submarine power cables affect the functioning of a common bivalve?
Kornholt_2022_J.Am.Med.Dir.Assoc__ Scoping Review of Randomized Trials With Discontinuation of Medicines in Older Adults
Kukavica_2022_Biol.Trace.Elem.Res__ Oxidative Stress and Neurotoxicity of Cadmium and Zinc on Artemia franciscana
Li_2022_Environ.Sci.Technol__ Identification of Novel Organophosphate Esters in Hydroponic Lettuces (Lactuca sativa L.): Biotransformation and Acropetal Translocation
Ma_2022_Front.Public.Health_10_901485 Pesticide Residues in Commonly Consumed Vegetables in Henan Province of China in 2020
Maestre-Serrano_2022_J.Am.Mosq.Control.Assoc__ Susceptibility to organophosphate in culex quinquefasciatus from colombia
Nandi_2022_Pestic.Biochem.Physiol_185_105138 The growing concern of chlorpyrifos exposures on human and environmental health
Navarrete-Carballo_2022_J.Am.Mosq.Control.Assoc__ INSECTICIDE SUSCEPTIBILITY TESTS OF AEDES TAENIORHYNCHUS IN YUCATAN, MEXICO
Onder_2022_Chem.Biol.Interact_363_110029 Chlorpyrifos oxon crosslinking of amyloid beta 42 peptides is a new route for generation of self-aggregating amyloidogenic oligomers that promote Alzheimer's disease
Palomino_2022_Parasit.Vectors_15_254 First national-scale evaluation of temephos resistance in Aedes aegypti in Peru
Pantelaki_2022_Environ.Res__113908 Occurrence and removal of organophosphate esters in municipal wastewater treatment plants in Thessaloniki, Greece
Rauf_2022_Pestic.Biochem.Physiol_184_105128 Malathion-resistant Tribolium castaneum has enhanced response to oxidative stress, immunity, and fitness
Ren_2022_Am.J.Transl.Res_14_3769 Prognostic role of NLGN2 and PTGDS in medulloblastoma based on gene expression omnibus
Roy_2022_PLoS.Negl.Trop.Dis_16_e0010304 Susceptibility status of the wild-caught Phlebotomus argentipes (Diptera: Psychodidae: Phlebotominae), the sand fly vector of visceral leishmaniasis, to different insecticides in Nepal
Salau_2022_Fundam.Clin.Pharmacol_30_12522 Ferulic Acid Mitigates Diabetic Cardiomyopathy via Modulation of Metabolic Abnormalities in Cardiac tissues of Diabetic Rats
Siddique_2022_Environ.Int_166_107402 Exposure of men living in the greater Montreal area to organophosphate esters: Association with hormonal balance and semen quality
Ssemugabo_2022_Environ.Health.Insights_16_11786302221111866 Pesticide Residues in Fresh Fruit and Vegetables from Farm to Fork in the Kampala Metropolitan Area, Uganda
Taketomi_2022_Front.Immunol_13_923265 Regulatory Roles of Phospholipase A(2) Enzymes and Bioactive Lipids in Mast Cell Biology
Thirukkumaran_2022_Methods.Mol.Biol_2525_207 Single-Cell NanoBRET Imaging with Green-Range HaloTag Acceptor
Wang_2022_J.Asian.Nat.Prod.Res__1 Penicipurate A, a new polyketide derivative from the endophytic fungus Penicillium purpurogenum
Wei_2022_Chemosphere__135700 Biodegradation of polybutylene adipate-co-terephthalate by Priestia megaterium, Pseudomonas mendocina, and Pseudomonas pseudoalcaligenes following incubation in the soil
Wu_2022_Food.Res.Int_158_111497 The inhibition mechanism of polyphenols from Phyllanthus emblica Linn. fruit on acetylcholinesterase: A interaction, kinetic, spectroscopic, and molecular simulation study
Yilmaz_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109416 In vitro and in silico evaluation of inhibitory effects of bisphenol derivatives on acetylcholinesterase of electric eel (Electrophorus electricus L.)
Zhang_2022_Front.Vet.Sci_9_909039 Genome-Wide Detection of Copy Number Variations and Evaluation of Candidate Copy Number Polymorphism Genes Associated With Complex Traits of Pigs
Zhao_2022_Theor.Appl.Genet_135_3323 Mutation in BrGGL7 gene encoding a GDSL esterase \/ lipase causes male sterility in Chinese cabbage (Brassica rapa L. ssp. pekinensis)
Zuin_2022_Sci.Rep_12_12214 Acetyl-cholinesterase-inhibitors slow cognitive decline and decrease overall mortality in older patients with dementia
Takahashi_2022_Biosci.Biotechnol.Biochem_86_294 Function of hydroxycinnamoyl spermidines in seedling growth of Arabidopsis
Nazarian_2022_Process.Biochem_121_439 Discovery of carboxylesterases via metagenomics: Putative enzymes that contribute to chemical kinetic resolution
Abbas_2022_Plants.(Basel)_11_ Novel Neuroprotective Potential of Bunchosia armeniaca (Cav.) DC against Lipopolysaccharide Induced Alzheimer's Disease in Mice
Abdel_2022_Nat.Prod.Res__1 Acetylcholinesterase inhibitors from Conocarpus lancifolius Engl. (Combretaceae)
Abi_2022_Int.J.Mol.Sci_23_ Treatment of Mouse Sperm with a Non-Catalytic Mutant of PLA2G10 Reveals That PLA2G10 Improves In Vitro Fertilization through Both Its Enzymatic Activity and as Ligand of PLA2R1
Afzal_2022_Biomolecules_12_ Anti-Huntington's Effect of Rosiridin via Oxidative Stress\/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents
Ahmad_2022_Molecules_27_ In Vitro and In Silico Investigation of Diterpenoid Alkaloids Isolated from Delphinium chitralense
Ajayi_2022_Metab.Brain.Dis__ Repeated social defeat stress exacerbates lipopolysaccharide-induced behavioural deficits in mice: ameliorative role of Chrysophyllum albidum fruit extract through anti-neuroinflammation, antioxidant and neurochemical balance
Aladodo_2022_Evid.Based.Complement.Alternat.Med_2022_4388941 Toxicological Evaluation and In Silico Identification of Acetylcholinesterase Inhibitors in a Commercial Polyherbal Formulation (KWAPF01)
Alcantara-Quintana_2022_Cancer.Manag.Res_14_2225 Effect of Exosomes from Patients with Grade One Cervical Intraepithelial Neoplasia on Cell Cultures: A Preliminary Study
Alharbi_2022_Medicina.(Kaunas)_58_ Rosinidin Protects Streptozotocin-Induced Memory Impairment-Activated Neurotoxicity by Suppressing Oxidative Stress and Inflammatory Mediators in Rats
Ali_2022_Bioorg.Chem_127_105944 Isolation, derivatization, in-vitro, and in-silico studies of potent butyrylcholinesterase inhibitors from Berberis parkeriana Schneid
Al-Khayri_2022_Plants.(Basel)_11_ Phenolic Profile and Antioxidant, Anticholinergic, and Antibacterial Properties of Corn Tassel
Alqahtani_2022_Molecules_27_ Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation
Anil_2022_Comput.Biol.Chem_100_107748 Exploring enzyme inhibition profiles of novel halogenated chalcone derivatives on some metabolic enzymes: Synthesis, characterization and molecular modeling studies
Anupama_2022_Mol.Neurobiol__ Jatamansinol from Nardostachys jatamansi Ameliorates Tau-Induced Neurotoxicity in Drosophila Alzheimer's Disease Model
Baba_2022_EClinicalMedicine_51_101571 Effect of donepezil for dementia prevention in Parkinson's disease with severe hyposmia (The DASH-PD study): A randomized long-term placebo-controlled trial
Bahloul_2022_Am.J.Trop.Med.Hyg__ Prognostic Value of Serum Cholinesterase Activity in Severe SARS-CoV-2-Infected Patients Requiring Intensive Care Unit Admission
Baik_2022_BMC.Geriatr_22_609 Prevalence and patterns of the concurrent use of anticholinergics for the motor symptoms of Parkinson's disease and acetylcholinesterase inhibitors in Parkinson's disease patients with dementia: a cross-sectional study using Korea National Health Insurance claims data
Banaei_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109423 Toxic effects of polyethylene microplastics on transcriptional changes, biochemical response, and oxidative stress in common carp (Cyprinus carpio)
Barbarin_2022_Mar.Pollut.Bull_182_113979 First study on the determination of baseline biomarkers in Mimachlamys varia for an intra-port environmental biomonitoring in French Atlantic coastline (La Rochelle)
Bhatia_2022_Toxins.(Basel)_14_ Evaluating Antivenom Efficacy against Echis carinatus Venoms-Screening for In Vitro Alternatives
Bi_2022_Bull.Exp.Biol.Med_173_346 A New Berberine Preparation Protects Pancreatic Islet Cells from Apoptosis Mediated by Inhibition of Phospholipase A(2)\/p38 MAPK Pathway
Brunst_2022_ACS.Med.Chem.Lett_13_1062 Designing a Small Fluorescent Inhibitor to Investigate Soluble Epoxide Hydrolase Engagement in Living Cells
Chen_2022_Antioxidants.(Basel)_11_1383 Main Bioactive Components and Their Biological Activities from Natural and Processed Rhizomes of Polygonum sibiricum
Chen_2022_J.Nanobiotechnology_20_347 N-acylhomoserine lactonase-based hybrid nanoflowers: a novel and practical strategy to control plant bacterial diseases
Costantino_2022_Arch.Pharm.(Weinheim)__e2200142 Toward the cholinesterase inhibition potential of TADDOL derivatives: Seminal biological and computational studies
Dai_2022_Environ.Sci.Pollut.Res.Int__ Integrative analysis uncovers response mechanism of Pirata subpiraticus to chronic cadmium stress
Danisman_2022_Neurochem.Res__ The Role of Acetylcholine on the Effects of Different Doses of Sulfite in Learning and Memory
Daroi_2022_Metab.Brain.Dis__ p-Coumaric acid protects against D-galactose induced neurotoxicity by attenuating neuroinflammation and apoptosis in mice brain
de Lima_2022_Fungal.Biol_126_471 Pestalotiopsis mangiferae isolated from cocoa leaves and concomitant tannase and gallic acid production
Decker_2022_Biomolecules_12_ Concurrent Change in Serum Cholinesterase Activity and Midregional-Proadrennomedullin Level Could Predict Patient Outcome following Liver Transplantation
Dibacto_2022_IBRO.Neurosci.Rep_13_107 In vitro anticholinesterase potential of some spices consumed in Cameroon and their protective effects on hydrogen peroxide-mediated oxidative stress damage in SK-N-SH cells
Dijk_2022_Circulation__ Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia
Dilshad_2022_Biomed.Res.Int_2022_8010395 Chemical Composition and Biological Evaluation of Typha domingensis Pers. to Ameliorate Health Pathologies: In Vitro and In Silico Approaches
Elmorsy_2022_Brain.Sci_12_ An Investigation of the Neurotoxic Effects of Malathion, Chlorpyrifos, and Paraquat to Different Brain Regions
Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 Aminoalkoxy-substituted coumarins: Synthesis and evaluation for reactivation of inhibited human acetylcholinesterase
Ferrandino_2022_Environ.Toxicol.Pharmacol_94_103934 Histological alterations and oxidative stress in adult zebrafish muscle after aluminium exposure
Fu_2022_Genes.(Basel)_13_ Identification of Differential Expression Genes between Volume and Pressure Overloaded Hearts Based on Bioinformatics Analysis
Gabaldo_2022_Biomolecules_12_ Usefulness of the Measurement of Serum Paraoxonase-1 Arylesterase Activity in the Diagnoses of COVID-19
Giannakopoulou_2022_Biomolecules_12_ Development of a Multi-Enzymatic Approach for the Modification of Biopolymers with Ferulic Acid
Gilani_2022_ACS.Omega_7_24231 Antiamnesic Potential of Malvidin on Aluminum Chloride Activated by the Free Radical Scavenging Property
Guimaraes_2022_Molecules_27_ Tuning Immobilized Commercial Lipase Preparations Features by Simple Treatment with Metallic Phosphate Salts
Haddad_2022_Health.Psychol.Res_10_37023 Aduhelm, a novel anti-amyloid monoclonal antibody, for the treatment of Alzheimer's Disease: A comprehensive review
Hao_2022_J.Agric.Food.Chem_70_9337 Construction, Pesticidal Activities, Control Effects, and Detoxification Enzyme Activities of Osthole Ester\/Amide Derivatives
He_2022_Metabolites_12_ The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells
Henstra_2022_Front.Psychiatry_13_953686 Rivastigmine for ECT-induced cognitive adverse effects in late life depression (RECALL study): A multicenter, randomized, double blind, placebo-controlled, cross-over trial in patients with depression aged 55 years or older: Rationale, objectives and methods
Herbet_2022_J.Clin.Med_11_ Amaryllidaceae, Lycopodiaceae Alkaloids and Coumarins-A Comparative Assessment of Safety and Pharmacological Activity
Hoang_2022_Trials_23_623 Noradrenergic Add-on Therapy with Extended-Release Guanfacine in Alzheimer's Disease (NorAD): study protocol for a randomised clinical trial and COVID-19 amendments
Hu_2022_Front.Med.(Lausanne)_9_944547 Development and Validation of a Non-invasive Model to Predict Liver Histological Lesions in Chronic Hepatitis B Patients With Persistently Normal Alanine Aminotransferase and Detectable Viremia
Huang_2022_Pract.Lab.Med_31_e00298 Time-dependent effects of storage at -80 C on the stability of butyrylcholinesterase activity in human serum
Hussein_2022_Arch.Razi.Inst_77_483 Molecular Study of Acinetobacter baumannii that Lacking Some Essentials Genes Responsible of Toxin-Antitoxin System
Imbault_2022_Front.Neurosci_16_885313 Cerebrospinal Fluid Proteomics in Friedreich Ataxia Reveals Markers of Neurodegeneration and Neuroinflammation
Jarne-Ferrer_2022_Pharmaceuticals.(Basel)_15_ A Combined Chronic Low-Dose Soluble Epoxide Hydrolase and Acetylcholinesterase Pharmacological Inhibition Promotes Memory Reinstatement in Alzheimer's Disease Mice Models
Jiao_2022_Genes.(Basel)_13_ Genome-Wide Analysis of the GDSL Genes in Pecan (Carya illinoensis K. Koch): Phylogeny, Structure, Promoter Cis-Elements, Co-Expression Networks, and Response to Salt Stresses
Kaur_2022_Cent.Nerv.Syst.Agents.Med.Chem_22_68 Design, Synthesis and Evaluation of Benzimidazole Hybrids to Inhibit Acetylcholinesterase and COX for Treatment of Alzheimer's Disease
Kemadjou_2022_Heliyon_8_e09896 The neuroprotective effect of Xylopia parviflora against aluminum chloride-induced neurotoxicity in rats
Khasawneh_2022_PLoS.One_17_e0269082 Corpus callosum anatomical changes in Alzheimer patients and the effect of acetylcholinesterase inhibitors on corpus callosum morphometry
Kim_2022_Molecules_27_ Honeysuckle Berry (Lonicera caerulea L.) Inhibits Lipase Activity and Modulates the Gut Microbiota in High-Fat Diet-Fed Mice
Kleiz-Ferreira_2022_Int.J.Mol.Sci_23_ Pharmacological Screening of Venoms from Five Brazilian Micrurus Species on Different Ion Channels
Knez_2022_Molecules_27_ Screening of Big Pharma's Library against Various in-house Biological Targets
Koirala_2022_Biomolecules_12_ Biotechnological Approaches to Optimize the Production of Amaryllidaceae Alkaloids
Kojima_2022_J.Appl.Glycosci.(1999)_69_35 Acetylated Xylan Degradation by Glycoside Hydrolase Family 10 and 11 Xylanases from the White-rot Fungus Phanerochaete chrysosporium
Korkmaz_2022_Biotechnol.Appl.Biochem__ 2-Amino thiazole derivatives as inhibitors of some metabolic enzymes: An in vitro and in silico study
Kosinska_2022_Int.J.Mol.Sci_23_ Synthesis and Biological Studies of Novel Aminophosphonates and Their Metal Carbonyl Complexes (Fe, Ru)
Kudo_2022_Biosci.Biotechnol.Biochem__ Mass spectrometry-guided discovery of new analogues of bicyclic phosphotriester salinipostin and evaluation of their monoacylglycerol lipase inhibitory activity
Kurt-Celep_2022_Antioxidants.(Basel)_11_ An In-Depth Study on the Metabolite Profile and Biological Properties of Primula auriculata Extracts: A Fascinating Sparkle on the Way from Nature to Functional Applications
Kwon_2022_Molecules_27_ The Influence of Tyrosol-Enriched Rhodiola sachalinensis Extracts Bioconverted by the Mycelium of Bovista plumbe on Scopolamine-Induced Cognitive, Behavioral, and Physiological Responses in Mice
Li_2022_J.Enzyme.Inhib.Med.Chem_37_2099 Fluorosulfate-containing pyrazole heterocycles as selective BuChE inhibitors: structure-activity relationship and biological evaluation for the treatment of Alzheimer's disease
Li_2022_Biotechnol.Adv__108026 Delineating biosynthesis of Huperzine A, A plant-derived medicine for the treatment of Alzheimer's disease
Liang_2022_Antioxidants.(Basel)_11_ Bioactive Components from Ampelopsis japonica with Antioxidant, Anti-alpha-Glucosidase, and Antiacetylcholinesterase Activities
Lim_2022_Am.J.Vet.Res_83_ Lipases: it's not just pancreatic lipase!
Liu_2022_Front.Aging.Neurosci_14_922650 A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer's Disease by Dual Inhibition of Acetylcholinesterase and Inflammation
Liu_2022_J.Immunol.Res_2022_6051092 BCHE as a Prognostic Biomarker in Endometrial Cancer and Its Correlation with Immunity
Loring_2022_Molecules_27_ Speculation on How RIC-3 and Other Chaperones Facilitate alpha7 Nicotinic Receptor Folding and Assembly
Losada-Perez_2022_PLoS.Genet_18_e1010329 Synaptic components are required for glioblastoma progression in Drosophila
Mafakheri_2022_Sci.Rep_12_12758 Synthesis of Candida Antarctica Lipase B (CALB) enzyme-powered magnetite nanomotor based on PCL\/Chitosan Janus nanostructure
Mahic_2022_Neurol.Ther__1 Physician-Reported Perspectives on Myasthenia Gravis in the United States: A Real-World Survey
Majidazar_2022_Eur.J.Clin.Pharmacol__ Pharmacotherapy of Alzheimer's disease: an overview of systematic reviews
Mashal_2022_Biomolecules_12_ Comparison of Tau and Amyloid-beta Targeted Immunotherapy Nanoparticles for Alzheimer's Disease
Maxwell_2022_Chem.Biol.Interact__110065 Neuropathology and cholinesterase expression in the brains of octogenarians and older
Mlakic_2022_Eur.J.Med.Chem_241_114616 New naphtho\/thienobenzo-triazoles with interconnected anti-inflammatory and cholinesterase inhibitory activity
Moreira_2022_Int.J.Mol.Sci_23_8206 Carbamate Pesticides: Shedding Light on Their Impact on the Male Reproductive System
Munoz-Nunez_2022_Metabolites_12_ Assessments of Ceanothanes Triterpenes as Cholinesterase Inhibitors: An Investigation of Potential Agents with Novel Inspiration for Drug Treatment of Neurodegenerative Diseases
Nunes_2022_Biosensors.(Basel)_12_ Acetylcholinesterase Biosensor Based on Functionalized Renewable Carbon Platform for Detection of Carbaryl in Food
Oh_2022_Int.J.Biol.Macromol_217_910 Synthesis of 4-substituted benzyl-2-triazole-linked-tryptamine-paeonol derivatives and evaluation of their selective inhibitions against butyrylcholinesterase and monoamine oxidase-B
Ohyama_2022_Sci.Rep_12_13122 Pharmacovigilance study of the association between dipeptidyl peptidase-4 inhibitors and angioedema using the FDA Adverse Event Reporting System (FAERS)
Olasehinde_2022_Toxicol.Res_38_365 Neurotoxicity of anthracene and benz[a]anthracene involves oxidative stress-induced neuronal damage, cholinergic dysfunction and disruption of monoaminergic and purinergic enzymes
Olatunji_2022_Toxicol.Res_38_345 Effect of daflon-500, a flavonoid compound on chlorpyriphos-induced oxidative changes in the hypophysis and testes in adult male rats
Otocka-Kmiecik_2022_Nutrients_14_ Effect of Carotenoids on Paraoxonase-1 Activity and Gene Expression
Patel_2022_J.Alzheimers.Dis.Rep_6_349 Emerging Pathophysiological Mechanisms Linking Diabetes Mellitus and Alzheimer's Disease: An Old Wine in a New Bottle
Peng_2022_Genes.(Basel)_13_ RNAi Mediated Gene Silencing of Detoxification Related Genes in the Ectropis oblique
Piedra_2022_J.Am.Mosq.Control.Assoc__ Characterization of insecticide resistance in Aedes aegypti from the zoological garden of Havana,Cuba
Rycerz_2022_Pol.J.Vet.Sci_25_303 Immunoreactivity of acetylcholinesterase and M1 muscarinic receptors in the hippocampus and striatum of rats treated with Rebaudioside A
Saidi_2022_Antioxidants.(Basel)_11_ Phenolic Characterization Using cLC-DAD Analysis and Evaluation of In Vitro and In Vivo Pharmacological Activities of Ruta tuberculata Forssk
Salama_2022_Arch.Microbiol_204_526 Egyptian cobra (Naja haje haje) venom phospholipase A2: a promising antiviral agent with potent virucidal activity against simian rotavirus and bovine coronavirus
Saleem_2022_Metab.Brain.Dis_38_717 Sarcococca saligna ameliorated D-galactose induced neurodegeneration through repression of neurodegenerative and oxidative stress biomarkers
Salman_2022_Neurotoxicol__ Effects of pramipexole on beta-amyloid(1-42) memory deficits and evaluation of oxidative stress and mitochondrial function markers in the hippocampus of Wistar rat
Samad_2022_Metab.Brain.Dis__ Adenosine protects D-galactose induced alterations in rat model of aging via attenuating neurochemical profile and redox status
Samsonowicz-Gorski_2022_Molecules_27_ Intensification of Double Kinetic Resolution of Chiral Amines and Alcohols via Chemoselective Formation of a Carbonate-Enzyme Intermediate
Sharma_2022_ChemMedChem__ A Coumarin-donepezil Hybrid as a Blood-brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications and Biological Evaluation of Natural Coumarins
She_2022_Mar.Drugs_20_ New Carboxamides and a New Polyketide from the Sponge-Derived Fungus Arthrinium sp. SCSIO 41421
Silalai_2022_ACS.Omega_7_24302 New 1,2,3-Triazole-genipin Analogues and Their Anti-Alzheimer's Activity
Smith_2022_Neuropharmacol__109201 Neuropeptide Y modulates excitatory synaptic transmission and promotes social behavior in the mouse nucleus accumbens
Somkhit_2022_Int.J.Mol.Sci_23_ Microglia Remodelling and Neuroinflammation Parallel Neuronal Hyperactivation Following Acute Organophosphate Poisoning
Sun_2022_Foods_11_ Improving Effect of the Policosanol from Ericerus pela Wax on Learning and Memory Impairment Caused by Scopolamine in Mice
Sustar_2022_Front.Genet_13_936121 Early Discovery of Children With Lysosomal Acid Lipase Deficiency With the Universal Familial Hypercholesterolemia Screening Program
Swiatek_2022_Molecules_27_ Bridging the Chemical Profiles and Biological Effects of Spathodea campanulata Extracts: A New Contribution on the Road from Natural Treasure to Pharmacy Shelves
Szwajgier_2022_Nutrients_14_ Honeys as Possible Sources of Cholinesterase Inhibitors
Tanaka_2022_Microorganisms_10_ Aspergillus Hydrophobins: Physicochemical Properties, Biochemical Properties, and Functions in Solid Polymer Degradation
Tollenaere_2022_Molecules_27_ Action of Mangifera indica Leaf Extract on Acne-Prone Skin through Sebum Harmonization and Targeting C. acnes
Ustundag_2022_Toxicol.Mech.Methods__1 Morphine ameliorates pentylenetetrazole-induced locomotor pattern in zebrafish embryos\; mechanism involving regulation of opioid receptors, suppression of oxidative stress, and inflammation in epileptogenesis
Wahid_2022_Brain.Sci_12_ Amelioration of Scopolamine-Induced Cognitive Dysfunction in Experimental Mice Using the Medicinal Plant Salvia moorcroftiana
Wan_2022_Mikrochim.Acta_189_300 Highly stable acetylcholinesterase electrochemical biosensor based on polymerized ionic liquids microgel for pesticides detection
Wang_2022_Talanta_250_123746 Substrate-free fluorescence ratiometric detection of serum acetylcholinesterase activity with a self-assembled CsPbBr(3) perovskite nanocrystals\/tetraphenylporphyrin tetrasulfonic acid nanocomposite
Wang_2022_Biomed.Res.Int_2022_5621341 The Impact of Catalpol on Proliferation, Apoptosis, Migration, and Oxidative Stress of Lung Cancer Cells Based on Nrf2\/ARE Signaling
Wang_2022_Food.Chem_397_133810 Novel Ce-based coordination polymer nanoparticles with excellent oxidase mimic activity applied for colorimetric assay to organophosphorus pesticides
Wang_2022_Antioxidants.(Basel)_11_ Soluble Epoxide Hydrolase Inhibitor t-AUCB Ameliorates Vascular Endothelial Dysfunction by Influencing the NF-kB\/miR-155-5p\/eNOS\/NO\/IkB Cycle in Hypertensive Rats
Wang_2022_Front.Nutr_9_933193 From Function to Metabolome: Metabolomic Analysis Reveals the Effect of Probiotic Fermentation on the Chemical Compositions and Biological Activities of Perilla frutescens Leaves
Watanabe_2022_Nat.Commun_13_4413 Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A\/acyltransferases
Wigenstam_2022_Chem.Biol.Interact__110061 Supplemental treatment to atropine improves the efficacy to reverse nerve agent induced bronchoconstriction
Wu_2022_Comput.Math.Methods.Med_2022_7083022 TPPU Downregulates Oxidative Stress Damage and Induces BDNF Expression in PC-12 Cells
Wu_2022_Front.Pharmacol_13_905708 In Vitro and in Silico Analysis of Phytochemicals From Fallopia dentatoalata as Dual Functional Cholinesterase Inhibitors for the Treatment of Alzheimer's Disease
Xia_2022_Biosensors.(Basel)_12_ A Fast-Response AIE-Active Ratiometric Fluorescent Probe for the Detection of Carboxylesterase
Xiang_2022_Cell.Death.Dis_13_638 SARM1 deletion in parvalbumin neurons is associated with autism-like behaviors in mice
Xu_2022_Microb.Biotechnol__ Application of a novel fluorogenic polyurethane analogue probe in polyester-degrading microorganisms screening by microfluidic droplet
Yildirim_2022_Int.J.Mol.Sci_23_ Boron Nitride Nanoparticles Loaded with a Boron-Based Hybrid as a Promising Drug Carrier System for Alzheimer's Disease Treatment
Yu_2022_Molecules_27_4464 Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa
Yu_2022_Chemosphere_307_135751 The adverse effects of fluxapyroxad on the neurodevelopment of zebrafish embryos
Zhang_2022_Eur.J.Med.Chem_240_114606 Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease
Zhang_2022_Front.Oncol_12_944025 Recent Advances on the Role of ATGL in Cancer
Zhang_2022_Cells_11_ Mitigation of Memory Impairment with Fermented Fucoidan and lambda-Carrageenan Supplementation through Modulating the Gut Microbiota and Their Metagenome Function in Hippocampal Amyloid-beta Infused Rats
Zhang_2022_Int.J.Mol.Sci_23_7954 Functional and Transcriptome Analysis of Streptococcus pyogenes Virulence on Loss of Its Secreted Esterase
Zhao_2022_Insects_13_ The Role of Insect Symbiotic Bacteria in Metabolizing Phytochemicals and Agrochemicals
Zhao_2022_JCI.Insight__ Lysosomal acid lipase, CSF1R and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells
Zhu_2022_Front.Vet.Sci_9_779745 Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspring
Guo_2022_ACS.Catal_12_3397 Conformational selection in biocatalytic plastic degradation by PETase
Alshehri_2022_Evid.Based.Complement.Alternat.Med_2022_6726438 Succinimide Derivatives as Antioxidant Anticholinesterases, Anti-alpha-Amylase, and Anti-alpha-Glucosidase: In Vitro and In Silico Approaches
Babnigg_2022_Acta.Crystallogr.D.Struct.Biol_78_997 Data collection from crystals grown in microfluidic droplets
Batallan_2022_PLoS.One_17_e0271131 Ovariectomy reduces cholinergic modulation of excitatory synaptic transmission in the rat entorhinal cortex
Bohnen_2022_J.Neurol.Sci_440_120357 Decreased vestibular efficacy contributes to abnormal balance in Parkinson's disease
Ebrahimnejad_2022_Drug.Chem.Toxicol__1 Polyethyleneglycol-serine nanoparticles as a novel antidote for organophosphate poisoning: synthesis, characterization, in vitro and in vivo studies
El Kadiri_2022_BMC.Neurol_22_292 Novel copy number variation of COLQ gene in a Moroccan patient with congenital myasthenic syndrome: a case report and review of the literature
Garcia-Alberca_2022_Alzheimers.Dement.(N.Y)_8_e12338 Combined treatment with Ginkgo biloba extract EGb 761 plus acetylcholinesterase inhibitors improved cognitive function and neuropsychiatric symptoms in patients with mild cognitive impairment
Gupta_2022_J.Biomol.Struct.Dyn__1 Design, synthesis, extra-precision docking, and molecular dynamics simulation studies of pyrrolidin-2-one derivatives as potential acetylcholinesterase inhibitors
Haddad_2022_Health.Psychol.Res_10_31925 Aducanumab, a Novel Anti-Amyloid Monoclonal Antibody, for the Treatment of Alzheimer's Disease: A Comprehensive Review
Hong_2022_Curr.Alzheimer.Res__ Poststroke cognitive impairment: a longitudinal follow-up and pre\/poststroke mini-mental state examination comparison
Jayathilaka_2022_Fish.Shellfish.Immunol_128_196 Isolation and characterization of plasma-derived exosomes from olive flounder (Paralichthys olivaceus) and their wound healing and regeneration activities
Li_2022_Neurotoxicol__ Integrated Strategy of Network Pharmacology and in vitro Screening to Identify Mechanism of Diazinon-induced Hippocampal Neurotoxicity
Li_2022_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1208_123381 Simultaneous measurement of six biomarkers of dichlorvos in blood by ultra performance liquid chromatography-quadrupole\/electrostatic field orbitrap mass spectrometry
Lian_2022_Metab.Brain.Dis__ Protective effects of isofraxidin against scopolamine-induced cognitive and memory impairments in mice involve modulation of the BDNF-CREB-ERK signaling pathway
Llanes_2022_Curr.Med.Chem__ Anticholinesterase agents for Alzheimer's Disease treatment: an updated overview
Macedo_2022_Bioorg.Med.Chem_71_116952 Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease
Mendez-Rivera_2022_Aquat.Toxicol_250_106231 Effects of the insecticide beta-endosulfan on tadpoles of Isthmohyla pseudopuma (Anura: Hylidae)
Obaid_2022_RSC.Adv_12_19764 Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase
Olchanski_2022_Alzheimers.Dement__ Alzheimer's disease medication use and adherence patterns by race and ethnicity
Orrego_2022_PLoS.One_17_e0272603 Identification of reference genes and their validation for gene expression analysis in phytopathogenic fungus Macrophomina phaseolina
Ortega-Perez_2022_Pharm.Biol_60_1384 Evaluation of the toxicology, anti-lipase, and antioxidant effects of Callistemon citrinus in rats fed with a high fat-fructose diet
Paolino_2022_RSC.Med.Chem_13_873 Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors
Peng_2022_Anal.Chim.Acta_1221_340110 Development of a pH-Responsive, SO(4)(2-)-loaded Fe and N co-doped carbon quantum dots-based fluorescent method for highly sensitive detection of glyphosate
R_2022_Curr.Comput.Aided.Drug.Des__ Design synthesis and In vitro evaluation of Tacrine- Flavone hybrids as Multifunctional Cholinesterase inhibitors for Alzheimer's disease
Tampi_2022_Am.J.Psychiatry_179_528 Dementia Is More Than Memory Loss: Neuropsychiatric Symptoms of Dementia and Their Nonpharmacological and Pharmacological Management
Tsukui_2022_J.Laparoendosc.Adv.Surg.Tech.A__ Biochemical Evaluation of Laparoscopic Portoenterostomy for Treating Biliary Atresia and Redo for Failed Portoenterostomy
Wang_2022_Front.Endocrinol.(Lausanne)_13_874608 Identification and Characterization of Two Novel Compounds: Heterozygous Variants of Lipoprotein Lipase in Two Pedigrees With Type I Hyperlipoproteinemia
Waseem_2022_ACS.Omega_7_26723 Prospective Evaluation of an Amide-Based Zinc Scaffold as an Anti-Alzheimer Agent: In Vitro, In Vivo, and Computational Studies
Xie_2022_Food.Funct__ Zeaxanthin remodels cytoplasmic lipid droplets via beta3-adrenergic receptor signaling and enhances perilipin 5-mediated lipid droplet-mitochondrion interactions in adipocytes
Zhang_2022_Biotechnol.Appl.Biochem__ Bioactivity of hamamelitannin, flavokawain A, and triacetyl resveratrol as natural compounds: Molecular docking study, anti-colon cancer and anti-Alzheimer potentials
Abdelghany_2022_Biomarkers__1 Neuroprotective role of medicinal plant extracts evaluated in a scopolamine-induced rat model of Alzheimer's disease
Ahmad_2022_Fitoterapia__105268 Isolation, crystal structure, DFT calculation and molecular docking of uncinatine-A isolated from Delphinium uncinatum
Ajiboye_2022_Bioinform.Biol.Insights_16_11779322221115546 Effect of Flavonoid-Rich Extract From Dalbergiella welwitschii Leaf on Redox, Cholinergic, Monoaminergic, and Purinergic Dysfunction in Oxidative Testicular Injury: Ex Vivo and In Silico Studies
Bu_2022_J.Alzheimers.Dis__ Dysphagia Risk in Patients Prescribed Rivastigmine: A Systematic Analysis of FDA Adverse Event Reporting System
Choi_2022_Foods_11_ Optimization of Fermentation Conditions of Artemisia capillaris for Enhanced Acetylcholinesterase and Butyrylcholinesterase
Davis_2022_NPJ.Aging_8_9 Age-dependent cognitive impairment, hydrocephalus and leukocyte infiltration in transgenic mice with endothelial expression of human EPHX2
Diniso_2022_Plants.(Basel)_11_ Polyphenolic Contents, Free Radical Scavenging and Cholinesterase Inhibitory Activities of Dalbergiella welwitschii Leaf Extracts
Dissanayake_2022_Front.Mol.Neurosci_15_937974 Calcium bombs as harbingers of synaptic pathology and their mitigation by magnesium at murine neuromuscular junctions
Durmaz_2022_Arch.Pharm.(Weinheim)__e2200294 Synthesis, anticholinesterase activity, molecular docking, and molecular dynamic simulation studies of 1,3,4-oxadiazole derivatives
Fide_2022_Clin.EEG.Neurosci__15500594221120723 Normalized Theta but Increased Gamma Activity after Acetylcholinesterase Inhibitor Treatment in Alzheimer's Disease: Preliminary qEEG Study
Gao_2022_BMC.Genomics_23_591 Conceptual framework for the insect metamorphosis from larvae to pupae by transcriptomic profiling, a case study of Helicoverpa armigera (Lepidoptera: Noctuidae)
Hassan_2022_Molecules_27_ Advances on Therapeutic Strategies for Alzheimer's Disease: From Medicinal Plant to Nanotechnology
Ibrahim_2022_Neurotox.Res__ Neuroprotective Potential of Intranasally Delivered Sulforaphane-Loaded Iron Oxide Nanoparticles Against Cisplatin-Induced Neurotoxicity
Kozminski_2022_Int.J.Mol.Sci_23_ New Imaging Modality of COVID-19 Pneumonia Developed on the Basis of Alzheimer's Disease Research
Li_2022_Front.Nutr_9_961697 Therapeutic targets and functions of curcumol against COVID-19 and colon adenocarcinoma
Li_2022_Molecules_27_4910 Free Linoleic Acid and Oleic Acid Reduce Fat Digestion and Absorption In Vivo as Potent Pancreatic Lipase Inhibitors Derived from Sesame Meal
Lim_2022_J.Am.Vet.Med.Assoc_260_1249 Understanding lipase assays in the diagnosis of pancreatitis in veterinary medicine
Liu_2022_Sci.Rep_12_13649 Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors
Miao_2022_Pharm.Biol_60_1502 Aaptamine - a dual acetyl - and butyrylcholinesterase inhibitor as potential anti-Alzheimer's disease agent
Modanwal_2022_J.Biomol.Struct.Dyn__1 Development of QSAR model using machine learning and molecular docking study of polyphenol derivatives against obesity as pancreatic lipase inhibitor
Nascimento_2022_J.Mol.Model_28_252 In silico study of tacrine and acetylcholine binding profile with human acetylcholinesterase: docking and electronic structure
Ozturk_2022_Molecules_27_ Which Extraction Solvents and Methods Are More Effective in Terms of Chemical Composition and Biological Activity of Alceafasciculiflora from Turkey?
Samsonowicz-Gorski_2022_Int.J.Mol.Sci_23_ Promiscuous Lipase-Catalyzed Knoevenagel-Phospha-Michael Reaction for the Synthesis of Antimicrobial beta-Phosphono Malonates
Sipahioglu_2022_Front.Med.(Lausanne)_9_940533 Does serum butyrylcholinesterase level determine the severity and mortality of COVID-19 pneumonia?: Prospective study
Terao_2022_Ageing.Res.Rev__101709 Comparative efficacy of lithium and aducanumab for cognitive decline in patients with mild cognitive impairment or Alzheimer's disease: a systematic review and network meta-analysis
Wang_2022_Front.Immunol_13_955161 Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands
Wloka_2022_Sci.Rep_12_13641 Insect cuticular compounds affect Conidiobolus coronatus (Entomopthorales) sporulation and the activity of enzymes involved in fungal infection
Wondmeneh_2022_Biomed.Res.Int_2022_4978456 The Effect of Chemotherapy Induction Therapy on the Pancreas in Patients with Acute Lymphoblastic Leukemia
Yoshida_2022_Sci.Total.Environ__158020 Exposure to organophosphorus compounds of Japanese children and the indoor air quality in their residences
Yu_2022_Chemosphere_307_135940 Effects of conventional versus biodegradable microplastic exposure on oxidative stress and gut microorganisms in earthworms: A comparison with two different soils
Zhang_2022_Phytochemistry__113357 Investigations of specialised metabolites of endophyte Diaporthe destruens hosted in Illigera orbiculata C. Y. Wu
Zhao_2022_J.Ethnopharmacol__115641 Screening and identification of anti-acetylcholinesterase ingredients from Tianzhi granule based on ultrafiltration combined with ultra-performance liquid chromatography-mass spectrometry and in silico analysis
Zieniuk_2022_Molecules_27_ Lipase-Catalyzed Synthesis, Antioxidant Activity, Antimicrobial Properties and Molecular Docking Studies of Butyl Dihydrocaffeate
Behcet_2022_Arch.Pharm.(Weinheim)__e2200276 New PEPPSI-Pd-NHC complexes bearing 4-hydroxyphenylethyl group: Synthesis, characterization, molecular docking, and bioactivity properties
Bianchini_2022_Chem.Biol.Interact__110121 MeHg exposure impairs both the catecholaminergic and cholinergic systems resulting in motor and non-motor behavioral changes in Drosophila melanogaster
Campos_2022_Phytochem.Anal__ Alternative method for microenzymatic inhibition activities monitoring from Baccharis trimera extracts by CZE-UV
Chait_2022_Endocrinol.Metab.Clin.North.Am_51_539 Hypertriglyceridemia
Fidan_2022_Arch.Pharm.(Weinheim)__e2200152 Design, synthesis, acetylcholinesterase, butyrylcholinesterase, and amyloid-beta aggregation inhibition studies of substituted 4,4'-diimine\/4,4'-diazobiphenyl derivatives
Gungor_2022_Chem.Biodivers__ Synthesis, Biological Evaluation and Docking Study of Mono- and Di-sulfonamide Derivatives as Antioxidant Agents and Acetylcholinesterase Inhibitors
Hung_2022_Inquiry_59_469580221103925 Statewide Evaluation of the California Medical Supervision Program Using Cholinesterase Electronic Laboratory Reporting Data: An Update
Kannan_2022_Indian.J.Occup.Environ.Med_26_100 Morbidity Profile and Cholinesterase Levels among Sprayers in Selected Tea Plantations in South India
Kawamoto_2022_Pancreatology__ Endoplasmic stress-inducing variants in carboxyl ester lipase and pancreatic cancer risk
Kim_2022_Sci.Rep_12_14239 Effects of extracellular vesicles derived from oral bacteria on osteoclast differentiation and activation
Klainbart_2022_Vet.J__105883 Prevalence, clinical manifestations, laboratory findings, treatment, and outcome of intermediate syndrome in anticholinesterase pesticide intoxication of dogs: A retrospective study
Li_2022_Front.Cardiovasc.Med_9_959916 Association between CES1 rs2244613 and the pharmacokinetics and safety of dabigatran: Meta-analysis and quantitative trait loci analysis
Liu_2022_Plant.Foods.Hum.Nutr__ Insight into Isolation and Characterization of Phenolic Compounds from Hawthorn (Crataegus pinnatifida Bge.) with Antioxidant, Anti-Acetylcholinesterase, and Neuroprotective Activities
Liu_2022_BMC.Anesthesiol_22_267 The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial
Naidoo_2022_Rev.Soc.Bras.Med.Trop_55_e0131 Clustered Regularly Interspaced Short Palindromic Repeats\/ CRISPR associated protein 9-mediated editing of Schistosoma mansoni genes: Identifying genes for immunologically potent drug and vaccine development
Osman_2022_Environ.Sci.Pollut.Res.Int__ Biomarkers of imidacloprid toxicity in Japanese quail, Coturnix coturnix japonica
Pacule_2022_Exp.Parasitol__108359 (R)-Carvone is a potential soil fumigant against Meloidogyne incognita whose likely enzymatic target in the nematode is acetylcholinesterase
Pang_2022_Cell_185_1793 In situ identification of cellular drug targets in mammalian tissue
Panza_2022_Exp.Neurol__114203 Hereditary spastic paraplegia: Genetic heterogeneity and common pathways
Pesaresi_2022_Chem.Biol.Interact__110092 Kinetic and structural studies on the inhibition of acetylcholinesterase and butyrylcholinesterase by a series of multitarget-directed galantamine-peptide derivatives
Qu_2022_Sci.Total.Environ_851_158146 Integrative assessment of biomarker responses in Mytilus galloprovincialis exposed to seawater acidification and copper ions
Raj_2022_Environ.Res__114011 Recent advances in assessment methods and mechanism of microbe-mediated chlorpyrifos remediation
Ramachandran_2022_PLoS.One_17_e0270084 Essential oil composition of Callistemon citrinus (Curtis) and its protective efficacy against Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae)
Ramirez_2022_iScience_25_104803 Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3
Ren_2022_Clin.Lab_68_ Predictive Value of Serum Lipoprotein-Associated Phospholipase A2 for Type 2 Diabetes Mellitus Complicated with Metabolic Syndrome in Elderly Patients
Rizzi_2022_Brain.Connect__ Cholinesterase inhibitors response might be related to right hippocampal functional connectivity in mild Alzheimer's disease
Siddique_2022_Curr.Res.Pharmacol.Drug.Discov_3_100120 Comparative study of rivastigmine and galantamine on the transgenic Drosophila model of Alzheimer's disease
Sosnowski_2022_Am.J.Physiol.Heart.Circ.Physiol__ Cardiomyocyte-specific disruption of soluble epoxide hydrolase limits inflammation to preserve cardiac function
Swaraz_2022_Chem.Biodivers__ Polyphenols profile and enzyme inhibitory properties of Blumea lacera (Burm. f.) DC.: a potential candidate against obesity, aging, and skin disorder
Tang_2022_Front.Genet_13_909091 Comparative Study of the Molecular Characterization, Evolution, and Structure Modeling of Digestive Lipase Genes Reveals the Different Evolutionary Selection Between Mammals and Fishes
Tantawy_2022_Bioorg.Chem_128_106098 Facile synthesis, larvicidal activity, biological effects, and molecular docking of sulfonamide-incorporating quaternary ammonium iodides as acetylcholinesterase inhibitors against Culex pipiens L
Toum_2022_Chem.Commun.(Camb)__ Highly sensitive acetylcholine biosensing via chemical amplification of enzymatic processes in nanochannels
Umar_2022_Chem.Biol.Drug.Des__ Recent Updates in Development of Small Molecules as Potential Clinical Candidates for Alzheimer's Disease: A Review
Vives-Rodriguez_2022_Alzheimers.Dement.(N.Y)_8_e12320 Impact of amyloid PET in the clinical care of veterans in a tertiary memory disorders clinic
Wang_2022_Front.Vet.Sci_9_948873 MicroRNA-199a-3p regulates proliferation and milk fat synthesis of ovine mammary epithelial cells by targeting VLDLR
Xu_2022_Cells_11_ Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms
Zeng_2022_Front.Pharmacol_13_962480 Baseline lymphocyte and cholinesterase levels may be the predictors of chronic herbal drug-induced liver injury
Zhu_2022_Sci.Total.Environ_845_157364 Neurotoxicity of tetrabromobisphenol A and SiO2 nanoparticle co-exposure in zebrafish and barrier function of the embryonic chorion
Czapinska_2022_Angew.Chem.Int.Ed.Engl__ The Nsigma-Rule for Serine, but Not Cysteine Catalytic Triads
Akhter_2022_PLoS.One_17_e0273368 Optimization and characterization of alkaliphilic lipase from a novel Bacillus cereus NC7401 strain isolated from diesel fuel polluted soil
Barman_2022_Arch.Microbiol_204_580 Characterization and purification of esterase from Cellulomonas fimi DB19 isolated from Zanthoxylum armatum with its possible role in diesel biodegradation
Chen_2022_Ecotoxicol.Environ.Saf_243_114007 2, 5-dichloro-1, 4-benuinone exposure to zebrafish embryos\/larvae causes neurodevelopmental toxicity
Cuciniello_2022_Free.Radic.Biol.Med__ Conjugated linoleic acid downregulates Alzheimer's hallmarks in aluminum mouse model through an Nrf2-mediated adaptive response and increases brain glucose transporter levels
Dai_2022_Biomed.Pharmacother_154_113576 Anti-Alzheimer's disease potential of traditional chinese medicinal herbs as inhibitors of BACE1 and AChE enzymes
Du_2022_Chem.Biodivers__ Coumarins from Sarcandra glabra (Thunb.) Nakai and Acetylcholinesterase Inhibiting Activity
Dwi_2022_Iran.Biomed.J_26_252 Update on Non-Alcoholic Fatty Liver Disease-Associated Single Nucleotide Polymorphisms and Their Involvement in Liver Steatosis, Inflammation, and Fibrosis: A Narrative Review
Feng_2022_Cell.Mol.Life.Sci_79_498 Sertoli cell survival and barrier function are regulated by miR-181c\/d-Pafah1b1 axis during mammalian spermatogenesis
Gao_2022_Protein.Pept.Lett__ The Interaction Between Two Metabolites of Polygala Tenuifolia and Cholinesterases
Gouvinhas_2022_Molecules_27_ Seed Phytochemical Profiling of Three Olive Cultivars, Antioxidant Capacity, Enzymatic Inhibition, and Effects on Human Neuroblastoma Cells (SH-SY5Y)
Guerineau_2022_Life.(Basel)_12_ Properties of Human Gastric Lipase Produced by Plant Roots
Gutierrez-Dominguez_2022_Int.J.Mol.Sci_23_ Identification of a Novel Lipase with AHSMG Pentapeptide in Hypocreales and Glomerellales Filamentous Fungi
Hasanvand_2022_Front.Chem_10_882191 Novel 3-aminobenzofuran derivatives as multifunctional agents for the treatment of Alzheimer's disease
Heiligenthal_2022_Anal.Bioanal.Chem__ Analysis of double-emulsion droplets with ESI mass spectrometry for monitoring lipase-catalyzed ester hydrolysis at nanoliter scale
Hepnarova_2022_Toxicol.In.Vitro__105463 Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides
Jang_2022_Cells_11_ 2,4-Diacetylphloroglucinol Reduces Beta-Amyloid Production and Secretion by Regulating ADAM10 and Intracellular Trafficking in Cellular and Animal Models of Alzheimer's Disease
Jiang_2022_Molecules_27_ Two New Picoline-Derived Meroterpenoids with Anti-Acetylcholinesterase Activity from Ascidian-Derived Fungus Amphichorda felina
Kang_2022_J.Clin.Med_11_ Effectiveness of Nootropics in Combination with Cholinesterase Inhibitors on Cognitive Function in Mild-to-Moderate Dementia: A Study Using Real-World Data
Kumar_2022_3.Biotech_12_241 Insecticide susceptibility vis--vis molecular variations in geographical populations of fall armyworm, Spodoptera frugiperda (J.E. smith) in India
La Rocca_2022_Int.J.Mol.Sci_23_ Small-Molecules as Chemiluminescent Probes to Detect Lipase Activity
Li_2022_Talanta_252_123867 Ultrasensitive Acetylcholinesterase detection based on a surface-enhanced Raman scattering lever strategy for identifying nerve fibers
Liang_2022_J.Ethnopharmacol__115656 Carthamus tinctorius L.: A natural neuroprotective source for anti-Alzheimer's disease drugs
Liu_2022_Eur.J.Med.Chem_242_114689 Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease
Luo_2022_PLoS.One_17_e0273583 A network pharmacology-based approach to explore the therapeutic potential of Sceletium tortuosum in the treatment of neurodegenerative disorders
Luo_2022_Biosensors.(Basel)_12_ Biosensor Based on Covalent Organic Framework Immobilized Acetylcholinesterase for Ratiometric Detection of Carbaryl
Martins-Gomes_2022_Toxics_10_ Neurotoxicity Assessment of Four Different Pesticides Using In Vitro Enzymatic Inhibition Assays
Mazur_2022_Sci.Rep_12_14795 Lipase-mediated Baeyer-Villiger oxidation of benzylcyclopentanones in ester solvents and deep eutectic solvents
Mitra_2022_Oxid.Med.Cell.Longev_2022_7252882 Tacrine Derivatives in Neurological Disorders: Focus on Molecular Mechanisms and Neurotherapeutic Potential
Nan_2022_Curr.Issues.Mol.Biol_44_3779 Cloning and Molecular Characterization of HSL and Its Expression Pattern in HPG Axis and Testis during Different Stages in Bactrian Camel
Nozawa_2022_Neuron__ In vivo nanoscopic landscape of neurexin ligands underlying anterograde synapse specification
Onder_2022_Chem.Biol.Interact_366_110126 Toluidine blue O attenuates tau phosphorylation in N2a-APPSwe cells
Ortin-Bustillo_2022_Animals.(Basel)_12_ Evaluation of the Effect of Sampling Time on Biomarkers of Stress, Immune System, Redox Status and Other Biochemistry Analytes in Saliva of Finishing Pigs
Ottria_2022_Molecules_27_ 2-Arachidonoylglycerol Synthesis: Facile and Handy Enzymatic Method That Allows to Avoid Isomerization
Pisciotta_2022_J.Clin.Lipidol_S1933-2874_00235 Plasma HDL pattern, cholesterol efflux and cholesterol loading capacity of serum in carriers of a novel missense variant (Gly176Trp) of endothelial lipase
Rauff_2022_BMC.Gastroenterol_22_401 PNPLA3 and TM6SF2 genetic variants and hepatic fibrosis and cirrhosis in Pakistani chronic hepatitis C patients: a genetic association study
Rodriguez-Vargas_2022_Toxins.(Basel)_14_ Intraspecific Differences in the Venom of Crotalus durissus cumanensis from Colombia
Sajal_2022_Molecules_27_ Computer-Aided Screening of Phytoconstituents from Ocimum tenuiflorum against Diabetes Mellitus Targeting DPP4 Inhibition: A Combination of Molecular Docking, Molecular Dynamics, and Pharmacokinetics Approaches
Schurad_2022_Curr.Alzheimer.Res__ Comparative Bioavailability study of a Novel Multi-day Patch Formulation of Rivastigmine (twice weekly) with Exelon Transdermal Patch (daily). A randomized clinical trial
Seabra_2022_Parasitol.Int__102659 The role of cholinesterases in chagas disease
Severi_2022_J.Anat__ Butyrylcholinesterase distribution in the mouse gastrointestinal tract: An immunohistochemical study
Siddique_2022_Chem.Biol.Interact__110120 Beneficial effects of apigenin on the transgenic Drosophila model of Alzheimer's disease
Singh_2022_J.Mol.Model_28_281 Identification of natural inhibitors to inhibit C. acnes lipase through docking and simulation studies
Sousa_2022_Toxins.(Basel)_14_ Diversity of Phospholipases A(2) from Bothrops atrox Snake Venom: Adaptive Advantages for Snakes Compromising Treatments for Snakebite Patients
Su_2022_Parkinsonism.Relat.Disord_103_50 Pisa syndrome in dementia with Lewy bodies: A Chinese multicenter study
Wang_2022_Front.Pharmacol_13_952876 Integrating network pharmacology analysis and pharmacodynamic evaluation for exploring the active components and molecular mechanism of moutan seed coat extract to improve cognitive impairment
Wu_2022_Toxins.(Basel)_14_ Lethal and Sublethal Toxicity Assessment of Cyclosporin C (a Fungal Toxin) against Plutella xylostella (L.)
Yim_2022_Elife_11_ A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag
Young_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2211136119 A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism
Yu_2022_Food.Chem_399_133949 Lipase-catalyzed production of pyridoxine monolaurate in solvent-free bioreactor system
Yu_2022_Methods.Enzymol_674_519 Strigolactone signaling complex formation in yeast: A paradigm for studying hormone-induced receptor interaction with multiple downstream proteins
Yu_2022_Phytochemistry_203_113394 Phloroglucinols with hAChE and alpha-glucosidase inhibitory activities from the leaves of tropic Rhodomyrtus tomentosa
Zafar_2022_Micromachines.(Basel)_13_ Development of Iron Nanoparticles (FeNPs) Using Biomass of Enterobacter: Its Characterization, Antimicrobial, Anti-Alzheimer's, and Enzyme Inhibition Potential
Zhang_2022_Food.Chem_399_133982 Chain-locked precursor ion scanning based HPLC-MS\/MS for in-depth molecular analysis of lipase-catalyzed transesterification of structured phospholipids containing w-3 fatty acyl chains
Zhang_2022_Analyst__ MnO(2)\/DNAzyme-mediated ratiometric fluorescence assay of acetylcholinesterase
Zhou_2022_Mol.Oncol__ Protein palmitoylation in cancer: molecular functions and therapeutic potential
Zhou_2022_Foods_11_ Future of Structured Lipids: Enzymatic Synthesis and Their New Applications in Food Systems
Zorbaz_2022_Neuronal.Signal_6_NS20210035 Cholinergic blockade of neuroinflammation: from tissue to RNA regulators
Abdel-Baki_2022_Plant.Foods.Hum.Nutr__ Ferocactus herrerae Fruits: Nutritional Significance, Phytochemical Profiling, and Biological Potentials
Ahmad_2022_World.J.Crit.Care.Med_11_228 Medicinal nicotine in COVID-19 acute respiratory distress syndrome, the new corticosteroid
Altay_2022_Chem.Biodivers__e202200348 A Biochemical Approach for Hedysarum candidissimum from Turkey: Screening Phytochemicals, Evaluation of Biological Activites, and Molecular Docking Study
Arab_2022_Antioxidants.(Basel)_11_ Phytochemicals as Modulators of Paraoxonase-1 in Health and Diseases
Attademo_2022_Environ.Monit.Assess_194_718 Effect of microplastics on the activity of carboxylesterase and phosphatase enzymes in Scinax squalirostris tadpoles
Begum_2022_Front.Pharmacol_13_946134 2-Mercaptobenzimidazole clubbed hydrazone for Alzheimer's therapy: In vitro, kinetic, in silico, and in vivo potentials
Bora_2022_Chem.Biol.Interact__110134 Synthesis, characterization, Evaluation of Metabolic Enzyme Inhibitors and in silico Studies of Thymol Based 2-Amino Thiol and Sulfonic Acid Compounds
Brown_2022_Methods.Mol.Biol_2547_427 The Pharmacogenetic Impact on the Pharmacokinetics of ADHD Medications
Chan_2022_Aust.N.Z.J.Psychiatry__48674221121091 Anti-dementia medication use in Aotearoa New Zealand: An exploratory study using health data from the Integrated Data Infrastructure (IDI)
Dang_2022_Phytother.Res__ Neuroprotective effects of total alkaloids fraction of Huperzia serrata on scopolamine-induced neurodegenerative animals
De BC#Zhang_2022_Nat.Commun_13_4896 Flavin-enabled reductive and oxidative epoxide ring opening reactions
Derat_2022_J.Phys.Chem.B_126_2449 Computational Advances in Protein Engineering and Enzyme Design
Eruygur_2022_Turk.J.Pharm.Sci_19_377 In Vitro Antioxidant and Enzyme Inhibition Activity of Tanacetum argyrophyllum (K. Koch) Tzvelev var. argyrophyllum Extract
Evangelista_2022_J.Enzyme.Inhib.Med.Chem_37_2395 A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
Faloye_2022_Bioinform.Biol.Insights_16_11779322221118330 Revealing the Acetylcholinesterase Inhibitory Potential of Phyllanthus amarus and Its Phytoconstituents: In Vitro and in Silico Approach
Gadelhaq_2022_Med.Vet.Entomol__ D-limonene nanoemulsion: lousicidal activity, stability, and effect on the cuticle of Columbicola columbae
Go_2022_J.Microbiol.Biotechnol_32_1 Korean Red Pine (Pinus densiflora) Bark Extract Attenuates Abeta-Induced Cognitive Impairment by Regulating Cholinergic Dysfunction and Neuroinflammation
Gonzalez-Naranjo_2022_J.Enzyme.Inhib.Med.Chem_37_2348 Multitarget drugs as potential therapeutic agents for alzheimer's disease. A new family of 5-substituted indazole derivatives as cholinergic and BACE1 inhibitors
Guo_2022_FEBS.J__ The UV-induced uptake of melanosome by skin keratinocyte is triggered by alpha7 nicotinic acetylcholine receptor-mediated phagocytosis
Li_2022_Endocr.J__ Does butyrylcholinesterase mediate exercise-induced and meal-induced suppression in acylated ghrelin?
Liu_2022_Pest.Manag.Sci__ Synthesis, insecticidal activity, and mode of action of novel imidazopyridine mesoionic derivatives containing an amido group
Lopes_2022_Chem.Biol.Drug.Des__ Evaluation of the Histamine H(3) Receptor Antagonists from LINS01 Series as Cholinesterases Inhibitors - Enzymatic and Modeling Studies
Luo_2022_BMC.Biotechnol_22_24 Metabolic engineering of energycane to hyperaccumulate lipids in vegetative biomass
Mani_2022_Plant.Biol.(Stuttg)__ Micro-morpho-anatomical transitions at various stages of in vitro development of Crinum malabaricum Lekhak and Yadav: A critically endangered medicinal plant
Mavridis_2022_Pest.Manag.Sci__ Next-generation molecular diagnostics (TaqMan qPCR and ddPCR) for monitoring insecticide resistance in Bemisia tabaci
Miao_2022_Insect.Sci__ Genome-wide identification, classification, and expression profiling of serine esterases and other esterase-related proteins in the tobacco hornworm, Manduca sexta
Mineur_2022_Mol.Psychiatry_27_4918 ACh signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms
Mohamed_2022_Med.Chem__ Recent Modifications of Anti-Dementia Agents Focusing on Tacrine and \/or Donepezil Analogs
Moon_2022_Endocrinol.Metab.(Seoul)_37_575 Lipoprotein Lipase: Is It a Magic Target for the Treatment of Hypertriglyceridemia
Nuzzo_2022_Cell.Mol.Neurobiol__ Neuroprotective and Antioxidant Role of Oxotremorine-M, a Non-selective Muscarinic Acetylcholine Receptors Agonist, in a Cellular Model of Alzheimer Disease
Ohira_2022_Mol.Genet.Metab.Rep_33_100913 LC-MS\/MS-based enzyme assay for lysosomal acid lipase using dried blood spots
Parween_2022_Neurotoxicol__ Chlorpyrifos and parathion regulate oxidative stress differentially through the expression of paraoxonase 2 in human neuroblastoma cell
Pergolizzi_2022_J.Exp.Clin.Cancer.Res_41_266 The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC\/beta-catenin pathway
Petric_2022_Acta.Chim.Slov_69_478 iFIT: An automated web tool for determining enzyme-kinetic parameters based on the high-curvature region of progress curves
Potter_2022_Lab.Chip__ Point-of-care SARS-CoV-2 sensing using lens-free imaging and a deep learning-assisted quantitative agglutination assay
Purushotham_2022_Exp.Brain.Res__ A perspective on molecular signalling dysfunction, its clinical relevance and therapeutics in autism spectrum disorder
Qiao_2022_J.Environ.Manage_322_115989 Oxidative stress and detoxification mechanisms of earthworms (Eisenia fetida) after exposure to flupyradifurone in a soil-earthworm system
Ragavendran_2022_Sci.Total.Environ__158502 Cladophialophora bantiana metabolites are efficient in the larvicidal and ovicidal control of Aedes Aegypti, and Culex Quinquefasciatus and have low toxicity in zebrafish embryo
Sasaki_2022_Biol.Pharm.Bull_45_1246 Intestinal Permeability of Drugs in Caco-2 Cells Cultured in Microfluidic Devices
Sasamoto_2022_FEBS.Open.Bio__ Functional analysis of the N-terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis
Schopfer_2022_Chem.Res.Toxicol__ Organophosphorus Pesticides Promote Protein Cross-Linking
Snehalatha_2022_J.Ethnopharmacol__115671 Standardization and Ameliorative effect of Kalyanaka ghrita in beta-amyloid induced memory impairment in wistar rats
Sun_2022_Mikrochim.Acta_189_363 Co, N co-doped porous carbon-based nanozyme as an oxidase mimic for fluorescence and colorimetric biosensing of butyrylcholinesterase activity
Tian_2022_Pest.Manag.Sci__ Comparative transcriptome analysis reveals the non-neuronal cholinergic system in the ovary of the oriental armyworm, Mythimna separata Walker (Lepidoptera: Noctuidae)
Traeger_2022_Tech.Coloproctol__ Effect of neuromuscular reversal with neostigmine\/glycopyrrolate versus sugammadex on postoperative ileus following colorectal surgery
Ucar_2022_Environ.Mol.Mutagen__ Ulexite modulates the neurotoxicological outcomes of acetylferrocene-exposed rainbow trout
Uytun_2022_J.Mol.Recognit__e2990 Synthesis of Novel Thiosemicarbazone Derivatives and Investigation of Their Dual AChE and MAO-B Inhibitor Effects
Wang_2022_Front.Neurol_13_933217 Molecular imaging biomarkers in familial frontotemporal lobar degeneration: Progress and prospects
Wright_2022_J.Alzheimers.Dis__ Plasma Myeloperoxidase as a Potential Biomarker of Patient Response to Anti-Dementia Treatment in Alzheimer's Disease
Wu_2022_Eur.J.Med.Chem_242_114701 Development and structure-activity relationship of tacrine derivatives as highly potent CDK2\/9 inhibitors for the treatment of cancer
Xia_2022_RSC.Adv_12_22295 Altereporenes A-E, five epoxy octa-hydronaphthalene polyketides produced by an endophytic fungus Alternaria sp. YUD20002
Yamamoto_2022_J.Pharmacol.Sci_150_123 Effects of Rikkunshi-To, a Japanese kampo medicine, on donepezil-induced gastrointestinal side effects in mice
Yang_2022_Toxicol.Res.(Camb)_11_654 Probing the interaction of superparamagnetic iron oxide nanoparticles with lipase and their interacting consequences at the molecular level
Zhang_2022_J.Clin.Lipidol__ GPIHBP1 autoantibody is an independent risk factor for the recurrence of hypertriglyceridemia-induced acute pancreatitis
Zhang_2022_Eur.J.Med.Chem_242_114695 Recent advance on pleiotropic cholinesterase inhibitors bearing amyloid modulation efficacy
Zhang_2022_ACS.Nano__ Translocation of Specific DNA Nanocarrier through an Ultrasmall Nanopipette: Toward Single-Protein-Molecule Detection with Superior Signal-to-Noise Ratio
Zuin_2022_Dis.Markers_2022_4264314 Paraoxonase-1 (PON-1) Arylesterase Activity Levels in Patients with Coronary Artery Disease: A Meta-Analysis
Ganeshpurkar_2022_Indian.J.Biochem.Biophys_59_619 Identification of potential AChE inhibitors through combined machine-learning and structure-based design approaches
Acosta-Jimenez_2022_Molecules_27_ QSTR Modeling to Find Relevant DFT Descriptors Related to the Toxicity of Carbamates
Ayinla_2022_J.Biomol.Struct.Dyn__1 Comparative modelling, molecular docking and immobilization studies on Rhizopus oryzae lipase: evaluation of potentials for fatty acid methyl esters synthesis
Bai_2022_Microbiome_10_147 Landscape of the gut archaeome in association with geography, ethnicity, urbanization, and diet in the Chinese population
Cacabelos_2022_Methods.Mol.Biol_2547_275 Pharmacogenomics of Alzheimer's Disease: Novel Strategies for Drug Utilization and Development
Ceccanti_2022_Front.Pharmacol_13_982434 Effects of 3,4-diaminopyridine on myasthenia gravis: Preliminary results of an open-label study
Dlouhy_2022_Cells_11_ Structural Entities Associated with Different Lipid Phases of Plant Thylakoid Membranes-Selective Susceptibilities to Different Lipases and Proteases
Dragomanova_2022_Molecules_27_ New Myrtenal-Adamantane Conjugates Alleviate Alzheimer's-Type Dementia in Rat Model
El-Kersh_2022_Molecules_27_ Unveiling Natural and Semisynthetic Acylated Flavonoids: Chemistry and Biological Actions in the Context of Molecular Docking
Gad_2022_Molecules_27_ GC-MS Chemical Profiling, Biological Investigation of Three Salvia Species Growing in Uzbekistan
Girard_2022_Molecules_27_ Chemical Synthesis and Biological Activities of Amaryllidaceae Alkaloid Norbelladine Derivatives and Precursors
Godoy_2022_Int.J.Mol.Sci_23_ Microbial Lipases and Their Potential in the Production of Pharmaceutical Building Blocks
Grott_2022_Chemosphere_308_136327 Influence of temperature on biomarker responses of bullfrog tadpoles (Lithobates catesbeianus) exposed to the herbicide ametryn
Habib_2022_Nutrients_14_ Polyphenol-Rich Date Palm Fruit Seed (Phoenix Dactylifera L.) Extract Inhibits Labile Iron, Enzyme, and Cancer Cell Activities, and DNA and Protein Damage
Hamilton_2022_Elife_11_ Fuzzy supertertiary interactions within PSD-95 enable ligand binding
Hendra_2022_J.Nat.Prod__ Spiroisoxazoline Inhibitors of Acetylcholinesterase from Pseudoceratina verrucosa. Quantitative Chiroptical Analysis of Configurational Heterogeneity, and Total Synthesis of (+\/-)-Methyl Purpuroceratate C
Istyastono_2022_Molecules_27_ PyPLIF HIPPOS and Receptor Ensemble Docking Increase the Prediction Accuracy of the Structure-Based Virtual Screening Protocol Targeting Acetylcholinesterase
Jaskiewicz_2022_Nutrients_14_ Evaluation of Activity of Sesquiterpene Lactones and Chicory Extracts as Acetylcholinesterase Inhibitors Assayed in Calorimetric and Docking Simulation Studies
Jurema_2022_Food.Res.Int_160_111730 Coffee simulated inhibition of pancreatic lipase and antioxidant activities: Effect of milk and decaffeination
Karaca_2022_RSC.Adv_12_23626 Synthesis of novel benzothiazole derivatives and investigation of their enzyme inhibitory effects against Alzheimer's disease
Kavaz_2022_Chem.Biodivers__ Anticholinergic, antioxidant, and antibacterial properties of Vitex agnus-castus L. seed extract : Assessment of its phenolic content by LC-MS\/MS
Khan_2022_Int.J.Mol.Sci_23_ Physiological and Molecular Response Modifications by Ultraviolet-C Radiation in Plutella xylostella and Its Compatibility with Cordyceps fumosorosea
Kolarevic_2022_Mutagenesis__ Single and combined potential of polystyrene microparticles and fluoranthene in the induction of DNA damage in haemocytes of Mediterranean mussel (Mytilus galloprovincialis)
Li_2022_Mol.Metab__101597 Endocannabinoids regulate cocaine-associated memory through brain AEA-CB1R signalling activation
Lins_2022_Chem.Biol.Interact__110136 BChE inhibitors from marine organisms - A review
Liu_2022_J.Transl.Med_20_418 Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins
Martinez_2022_Molecules_27_ Biocatalysts Synthesized with Lipase from Pseudomonas cepacia on Glycol-Modified ZIF-8: Characterization and Utilization in the Synthesis of Green Biodiesel
Ogunsuyi_2022_Drug.Chem.Toxicol__1 Curcumin improves the ability of donepezil to ameliorate memory impairment in Drosophila melanogaster: involvement of cholinergic and cnc\/Nrf2-redox systems
Patel_2022_Curr.Neurovasc.Res__ Insights of Valacyclovir in Treatment of Alzheimer's Disease: Computational Docking Studies and Scopolamine Rat Model
Pathak_2022_Ticks.Tick.Borne.Dis_13_102033 Dual assessment of transcriptional and metabolomic responses in the American dog tick following exposure to different pesticides and repellents
Pompermaier_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109461 Persistent and transgenerational effects of pesticide residues in zebrafish
Pourtaher_2022_Sci.Rep_12_15236 Design, synthesis, in silico and biological evaluations of novel polysubstituted pyrroles as selective acetylcholinesterase inhibitors against Alzheimer's disease
Ramachandran_2022_Arch.Insect.Biochem.Physiol__e21961 Toxicity of Ocimum americanum L. extracts against Aedes aegypti larvae (Diptera: Culicidae) and their impact on insecticide resistant
Richter_2022_J.Anal.Toxicol__ In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists 2F-QMPSB and SGT-233 Including Isozyme Mapping and Carboxylesterases Activity Testing
Saadullah_2022_Molecules_27_ Molecular Modeling Study of Novel Lancifolamide Bioactive Molecule as an Inhibitor of Acetylcholinesterase (AChE), Herpes Simplex Virus (HSV-1), and Anti-proliferative Proteins
Salah_2022_J.Biomol.Struct.Dyn__1 Novel 3-phenyl-1- (alkylphenyl)-9-oxa-4-azaphenanthren-10-ones as inhibitors of some enzymes: synthesis, characterization, biological evaluation and molecular docking studies
Sette_2022_Toxicology__153317 The Mechanistic Basis for the Toxicity Difference Between Juvenile Rats and Mice following Exposure to the Agricultural Insecticide Chlorpyrifos
Shimizu_2022_PLoS.One_17_e0274297 Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice
Shirbhate_2022_Curr.Top.Med.Chem__ Combination therapy for the treatment of alzheimer's disease: recent progress and future prospects
Song_2022_Sci.Rep_12_15290 Design, synthesis and insecticidal activity and mechanism research of Chasmanthinine derivatives
Stasinou_2022_Nutrients_14_ Association of rs738409 Polymorphism in Adiponutrin Gene with Liver Steatosis and Atherosclerosis Risk Factors in Greek Children and Adolescents
Sun_2022_J.Econ.Entomol__ The Detoxification Enzymatic Responses of Plutella xylostella (Lepidoptera: Plutellidae) to Cantharidin
Thiel_2022_Int.J.Mol.Sci_23_ Expression of the C-Terminal Domain of Phospholipase Cbeta3 Inhibits Signaling via Galphaq-Coupled Receptors and Transient Receptor Potential Channels
Truong_2022_Neurology__ Effect of Cholinesterase Inhibitors on Mortality in Patients With Dementia: A Systematic Review of Randomized and Nonrandomized Trials
Turgutalp_2022_J.Med.Chem__ Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer's Disease
Van Nguyen_2022_Chemosphere__136382 Integrated biomarker response in signal crayfish Pacifastacus leniusculus exposed to diphenhydramine
Vanin_2022_Sci.Rep_12_15376 Neuroprotective potential of Cannabis sativa-based oils in Caenorhabditis elegans
Wattanathorn_2022_Foods_11_ Memory-Enhancing Effect of 8-Week Consumption of the Quercetin-Enriched Culinary Herbs-Derived Functional Ingredients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Wei_2022_J.Hazard.Mater_441_129890 Encapsulating gold nanoclusters into metal-organic frameworks to boost luminescence for sensitive detection of copper ions and organophosphorus pesticides
Xu_2022_New.Phytol__ Karrikin Signaling Regulates Hypocotyl Shade Avoidance Response by Modulating Auxin Homeostasis in Arabidopsis
Xu_2022_Biomed.Pharmacother_153_113495 Activation of cholinergic basal forebrain neurons improved cognitive functions in adult-onset hypothyroid mice
Zhang_2022_Insect.Sci__ Characterization of neutral lipases revealed the tissue-specific TAG hydrolytic activity in Nilaparvata lugens
Zhou_2022_Chem.Biodivers__ Two new C18-diterpenoid alkaloids from Aconitum leucostomum Worosch
Zhuang_2022_Animals.(Basel)_12_ Effects of Fatty-Type and Lean-Type on Growth Performance and Lipid Droplet Metabolism in Pekin Ducks
Zou_2022_ACS.Appl.Mater.Interfaces__ Dual-Modal Nanoscavenger for Detoxification of Organophosphorus Compounds
Abdullah_2022_ACS.Omega_7_32360 Synthesis, Characterization, and Enzyme Inhibition Properties of 1,2,4-Triazole Bearing Azinane Analogues
Ali_2022_Antonie.Van.Leeuwenhoek__ Serratia sp. scl1: isolation of a novel thermostable lipase producing microorganism which holds industrial importance
Amirahmadi_2022_Inflammopharmacology__ Minocycline attenuates cholinergic dysfunction and neuro-inflammation-mediated cognitive impairment in scopolamine-induced Alzheimer's rat model
Angulo_2022_Biomedica_42_445 Neuroleptic malignant syndrome associated with acute organophosphate poisoning: Case report
Babu_2022_RSC.Adv_12_22476 Towards novel tacrine analogues: Pd(dppf)Cl(2)CH(2)Cl(2) catalyzed improved synthesis, in silico docking and hepatotoxicity studies
Balci_2022_Bioresour.Technol__127990 Continuous treatment of diethyl hexyl and dibutyl phthalates by fixed-bed reactor: comparison of two esterase bionanocomposites
Banoo_2022_Drug.Dev.Res__ Blood-brain barrier permeable benzylpiperidin-4-yl-linked benzylamino benzamides as dual cholinesterase inhibitors
Bao_2022_J.Mol.Cell.Biol__ Knockdown of hepatocyte Perilipin-3 mitigates hepatic steatosis and steatohepatitis caused by hepatocyte CGI-58 deletion in mice
Barchetta_2022_Biomedicines_10_ Dipeptidyl Peptidase 4 (DPP4) as A Novel Adipokine: Role in Metabolism and Fat Homeostasis
Bhanushali_2022_J.Mol.Liq_367_120359 Estimating thermodynamic equilibrium solubility and solute-solvent interactions of niclosamide in eight mono-solvents at different temperatures
Bosancic_2022_BMC.Anesthesiol_22_293 Association of cholinesterase activities and POD in older adult abdominal surgical patients
Cao_2022_Front.Endocrinol.(Lausanne)_13_992875 PRDX6: A protein bridging S-palmitoylation and diabetic neuropathy
Chen_2022_Mol.Metab__101600 Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma
Cobilinschi_2022_Toxics_10_ Toxic-Induced Nonthyroidal Illness Syndrome Induced by Acute Low-Dose Pesticides Exposure-Preliminary In Vivo Study
Cossette_2022_Can.Liver.J_5_428 Early diagnosis and successful long-term management of a rare, severe lysosomal acid lipase deficiency\/Wolman disease patient: Infancy to age five
Cunha-Silva_2022_Medicine.(Baltimore)_101_e30315 15-Year progression to liver cancer in the lack of treatment for lysosomal acid lipase deficiency: A case report
da Costa_2022_Cent.Nerv.Syst.Agents.Med.Chem_22_139 In silico Study of Acetylcholinesterase and Beta-secretase Inhibitors: Potential Multitarget Anti-Alzheimer's Agents
De Anna_2022_Pestic.Biochem.Physiol_187_105222 Chlorpyrifos stimulates ABCC-mediated transport in the intestine of the rainbow trout Oncorhynchus mykiss
de Bem Matos_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109468 Biochemical and histopathological responses in Nile tilapia exposed to a commercial insecticide mixture containing dinotefuran and lambda-cyhalothrin
Deng_2022_Front.Pharmacol_13_941522 Discovering monoacylglycerol lipase inhibitors by a combination of fluorogenic substrate assay and activity-based protein profiling
Depmeier_2022_Anal.Biochem__114889 HPLC fluorescence assay for measuring the activity of diacylglycerol lipases and the action of inhibitors thereof
Doherty_2022_Pharmacol.Res.Perspect_10_e01008 Prescribing cascades in community-dwelling adults: A systematic review
Fatai_2022_Ecotoxicol.Environ.Saf_244_114079 Effect of bisphenol F on sexual performance and quality of offspring in Male Wistar rats
George_2022_Nutr.Neurosci__1 An insight into the neuroprotective effects and molecular targets of pomegranate (Punica granatum) against Alzheimer's disease
Gerbelli_2022_Nanoscale.Adv_4_3592 Interaction between glyphosate pesticide and amphiphilic peptides for colorimetric analysis
Gok_2022_Biochimie__ Novel activity of human BChE: Lipid hydrolysis
Gok_2022_Front.Mol.Neurosci_15_941467 Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease
Gomes_2022_Environ.Sci.Pollut.Res.Int__ The aquatic macrophyte Salvinia molesta mitigates herbicides (glyphosate and aminomethylphosphonic acid) effects to aquatic invertebrates
Grisham_2022_Front.Pediatr_10_931336 Hypertriglyceridemia-induced acute pancreatitis in children: A mini-review
Guo_2022_Front.Pharmacol_13_992269 Protective effect of Monarda didymaL. essential oil and its main component thymol on learning and memory impairment in aging mice
Han_2022_Life.Sci_308_120942 Soluble epoxide hydrolase inhibitor, t-AUCB, improves salivary gland function by ameliorating endothelial injury
Harapas_2022_Sci.Immunol_7_eabi4611 DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1\/IL-1 signaling
Hosseinzadeh_2022_Toxicol.In.Vitro__105477 Precision cut tissue slices to investigate the effects of triclosan exposure in Mytilus galloprovincialis
Hsu_2022_J.Org.Chem__ From a Carbohydrate Raw Material to an Important Building Block: Cost-Efficient Conversion of d-Fructose into 2-Deoxy-l-ribose
Jeyavani_2022_Environ.Sci.Pollut.Res.Int__ Ingestion and impacts of water-borne polypropylene microplastics on Daphnia similis
Jiang_2022_Nat.Commun_13_5308 Preclinical and randomized clinical evaluation of the p38alpha kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration
Kabbani_2022_Cell.Rep_40_111321 Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice
Kadefors_2022_Front.Pharmacol_13_953771 Dipeptidyl peptidase 4 expression is not associated with an activated fibroblast phenotype in idiopathic pulmonary fibrosis
Katsigianni_2022_Cost.Eff.Resour.Alloc_20_51 A systematic review of economic evaluations of enzyme replacement therapy in Lysosomal storage diseases
Kim_2022_Curr.Issues.Mol.Biol_44_4282 Inhibitory Activity of Quaternary Isoquinoline Alkaloids on Soluble Epoxide Hydrolase
Kim_2022_NPJ.Regen.Med_7_49 Platelet-rich plasma loaded nerve guidance conduit as implantable biocompatible materials for recurrent laryngeal nerve regeneration
Kolesnikov_2022_Photochem.Photobiol__ Photoswitchable Phosphonate-fullerene Hybrids with Cholinesterase Activity
Lamsal_2022_Cureus_14_e27881 Treatment Modalities for Dementia in Down's Syndrome: A Literature Review
Lanzarin_2022_Chemosphere_308_136430 Evaluation of the developmental effects of a glyphosate-based herbicide complexed with copper, zinc, and manganese metals in zebrafish
Lazinski_2022_J.Med.Chem__ Bioactive Aurones, Indanones, and Other Hemiindigoid Scaffolds: Medicinal Chemistry and Photopharmacology Perspectives
Li_2022_Anim.Nutr_11_38 Probiotic effect of ferulic acid esterase-producing Lactobacillus plantarum inoculated alfalfa silage on digestion, antioxidant, and immunity status of lactating dairy goats
Li_2022_Environ.Int_169_107522 Insight into the uptake and metabolism of a new insecticide cyetpyrafen in plants
Liu_2022_Biochem.Pharmacol__115250 Emerging role of carboxylesterases in nonalcoholic fatty liver disease
Liu_2022_Environ.Sci.Pollut.Res.Int_30_12522 Fosthiazate exposure induces oxidative stress, nerve damage, and reproductive disorders in nontarget nematodes
Lolak_2022_Mol.Divers__ Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors
Macias-Alonso_2022_RSC.Adv_12_23747 Obtention of biodiesel through an enzymatic two-step process. Study of its performance and characteristic emissions
Mahfoudhi_2022_Biotechnol.Bioeng__ Fungal Lipases as Biocatalysts: a Promising Platform in Several Industrial Biotechnology Applications
Mittal_2022_RSC.Adv_12_23566 Fabrication of hydrolase responsive diglycerol based Gemini amphiphiles for dermal drug delivery applications
Mohammad_2022_Molecules_27_ Heterocyclic Compounds as Dipeptidyl Peptidase-IV Inhibitors with Special Emphasis on Oxadiazoles as Potent Anti-Diabetic Agents
Mosier_2022_Int.J.Sci.Res.Environ.Sci.Toxicol_5_ Inhibition of Serum Esterases in Juvenile Rats Repeatedly Exposed to Low Levels of Chlorpyrifos
O'Farrell_2022_Sci.Rep_12_15661 FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models
Palermo_2022_Toxicology__153322 Newly Scheduled Carbamate Compounds: A synopsis of their properties and development, and considerations for the scientific community
Park_2022_Front.Plant.Sci_13_969844 Applications and prospects of genome editing in plant fatty acid and triacylglycerol biosynthesis
Patel_2022_Biochem.Pharmacol_205_115248 Repositioning of tubocurarine as analgesic and anti-inflammatory agent: Exploring beyond myorelaxant activity
Saadullah_2022_Dose.Response_20_15593258221125478 Dose Dependent Effects of Breynia cernua Against the Paraquat Induced Parkinsonism like Symptoms in Animals' Model: In Vitro, In Vivo and Mechanistic Studies
Salib_2022_J.Org.Chem__ Bioactive Bromotyrosine Alkaloids from the Bahamian Marine Sponge Aiolochroia crassa. Dimerization and Oxidative Motifs
Salleh_2022_Z.Naturforsch.C.J.Biosci__ Chemical composition and anticholinesterase activity of Lepisanthes rubiginosa (Roxb.) Leenh. essential oil
Samal_2022_Front.Physiol_13_988907 Metabolic detoxification and ace-1 target site mutations associated with acetamiprid resistance in Aedes aegypti L
Sharma_2022_Sleep__ Acute sleep deprivation induces synaptic remodelling at the soleus muscle neuromuscular junction in rats
Shi_2022_Nanoscale.Adv_4_952 An esterase-activatable prodrug formulated liposome strategy: potentiating the anticancer therapeutic efficacy and drug safety
Sole_2022_Environ.Pollut_313_120149 Characterisation of plasmatic B-esterases in bottlenose dolphins (Tursiops truncatus) and their potential as biomarkers of xenobiotic chemical exposures
Stavroulaki_2022_Vet.Sci_9_ Serial Measurement of Serum Pancreatic Lipase Immunoreactivity, Feline Trypsin-like Immunoreactivity, and Cobalamin Concentrations in Kittens
Sun_2022_Andrology__ Saxagliptin alleviates erectile dysfunction through increasing SDF-1 in diabetes mellitus
Tao_2022_Inflammopharmacology__ Inhibitors of soluble epoxide hydrolase on acute lung injury: a meta-analysis of preclinical studies
Temel_2022_J.Trace.Elem.Med.Biol_74_127073 Cream production and biological in vivo\/in vitro activity assessment of a novel boron-based compound derived from quercetin and phenyl boronic acid
Turner_2022_Pharmacol.Res.Perspect_10_e01009 Effects of a recombinant humanized anti-cocaine monoclonal antibody on the metabolism and distribution of cocaine in vitro and in mice
Vassiliadi_2022_Gels_8_ (Hydroxypropyl)methyl Cellulose-Chitosan Film as a Matrix for Lipase Immobilization-Part II: Structural Studies
Venkatesan_2022_Eur.Rev.Med.Pharmacol.Sci_26_6344 Anti-amnesic and anti-cholinesterase activities of alpha-asarone against scopolamine-induced memory impairments in rats
Vieider_2022_J.Enzyme.Inhib.Med.Chem_37_1752 Synthesis and structure-activity relationships for some novel diflapolin derivatives with benzimidazole subunit
Villanacci_2022_Virchows.Arch__ Letter to the Editor on Beltman L et al. Diagnostic accuracy of calretinin and acetylcholinesterase staining of rectal suction biopsies in Hirschsprung disease examined by unexperienced pathologists
Wang_2022_J.Med.Entomol__ First Report of Mutations Associated With Pyrethroid (L1014F) and Organophosphate (G119S) Resistance in Belgian Culex (Diptera: Culicidae) Mosquitoes
Xiong_2022_Pestic.Biochem.Physiol_187_105184 Insecticidal and P450 mediate metabolism of fluralaner against red imported fire ant, Solenopsis invicta (Hymenoptera: Formicidae)
Xu_2022_Transbound.Emerg.Dis__ Comparative genomics of Sarcoptes scabiei provide new insights into adaptation to permanent parasitism and within-host species divergence
Xue_2022_Insects_13_ Sensitivity Differences and Biochemical Characteristics of Laodelphax striatellus (Falln) to Seven Insecticides in Different Areas of Shandong, China
Yang_2022_Anal.Chem__ Diagnosis of Alzheimer's Disease and In Situ Biological Imaging via an Activatable Near-Infrared Fluorescence Probe
Yang_2022_Arch.Insect.Biochem.Physiol__e21967 Comparative genomic analysis of carboxylesterase genes in Tenebrio molitor and other four tenebrionids
Yoshikawa_2022_PLoS.One_17_e0274161 Two-step nationwide epidemiological survey of myasthenia gravis in Japan 2018
Yousof_2022_Bioorg.Chem_129_106137 Discovery of potent and selective dual cholinesterases and beta-secretase inhibitors in pomegranate as a treatment for Alzheimer's disease
Zhang_2022_Int.J.Mol.Sci_23_8267 COX-2\/sEH Dual Inhibitor Alleviates Hepatocyte Senescence in NAFLD Mice by Restoring Autophagy through Sirt1\/PI3K\/AKT\/mTOR
Zhang_2022_Biotechnol.Adv__108036 Advances in enzyme biocatalysis for the preparation of functional lipids
Zhang_2022_J.Fungi.(Basel)_8_ Toxicological and Biochemical Description of Synergism of Beauveria bassiana and Emamectin Benzoate against Megalurothrips usitatus (Bagrall)
Zhu_2022_Pestic.Biochem.Physiol_187_105186 Functional characterization of CYP6G4 from the house fly in propoxur metabolism and resistance
Zhuang_2022_Biomed.Res.Int_2022_6962056 Development of a Clinical Prognostic Model for Metabolism-Related Genes in Squamous Lung Cancer and Correlation Analysis of Immune Microenvironment
Afzal_2022_Molecules_27_ Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress Leaded Caspase-3\/9 and TNF-alpha Signaling Pathways
Al Khashali_2022_Int.J.Mol.Sci_23_ Regulation of the Soluble Amyloid Precursor Protein alpha (sAPPalpha) Levels by Acetylcholinesterase and Brain-Derived Neurotrophic Factor in Lung Cancer Cell Media
Bai_2022_J.Phys.Chem.B_126_7797 Computationally Elucidating the Binding Kinetics for Different AChE Inhibitors to Access the Rationale for Improving the Drug Efficacy
Bernal Barquero_2022_Int.J.Mol.Sci_23_9251 Targeted Next-Generation Sequencing of Congenital Hypothyroidism-Causative Genes Reveals Unexpected Thyroglobulin Gene Variants in Patients with Iodide Transport Defect
Brinza_2022_Molecules_27_ Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (Danio rerio) Model: Involvement of Cholinergic System and Brain Oxidative Stress
Burmistrov_2022_Int.J.Mol.Sci_23_ Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety
Carocci_2022_Antioxidants.(Basel)_11_ Novel Phenothiazine\/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease
Cascaes_2022_Antioxidants.(Basel)_11_ Phytochemical Profile, Antioxidant Potential and Toxicity Evaluation of the Essential Oils from Duguetia and Xylopia Species (Annonaceae) from the Brazilian Amazon
Chelikani_2022_Cureus_14_e28215 A Rare Case of Hashimoto's Encephalopathy With Mosaic Turner Syndrome
Chou_2022_Nutrients_14_ Benefits of Valsartan and Amlodipine in Lipolysis through PU.1 Inhibition in Fructose-Induced Adiposity
Curie_2022_Polymers.(Basel)_14_ The Effect of Solvent Hydrophilicity on the Enzymatic Ring-Opening Polymerization of L-Lactide by Candida rugosa Lipase
Das_2022_J.Biomol.Struct.Dyn__1 A molecular docking-based comparative assessment of various anticholinergic drugs as antidotes to different nerve agent poisoning
Diez-Iriepa_2022_Antioxidants.(Basel)_11_ Polyfunctionalized alpha-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment
Durmaz_2022_Molecules_27_5902 Antioxidant, Antidiabetic, Anticholinergic, and Antiglaucoma Effects of Magnofluorine
Eissa_2022_Arch.Pharm.(Weinheim)__e2200398 Development of new Alzheimer's disease drug candidates using donepezil as a key model
Elfiky_2022_Cells_11_ A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn's Disease
Espeter_2022_Diagnostics.(Basel)_12_ Critically Ill COVID-19 Patients Show Reduced Point of Care-Measured Butyrylcholinesterase Activity-A Prospective, Monocentric Observational Study
Falb_2022_Cureus_14_e28183 Autoimmune Encephalopathy Associated With Anti-thyroid Antibodies: A Case Report
Gonzalez_2022_J.Steroid.Biochem.Mol.Biol__106194 Ring-fused 3beta-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties
Gunenc_2022_Subcell.Biochem_99_1 Fatty Acid Synthase: Structure, Function, and Regulation
Gupta_2022_Mini.Rev.Med.Chem__ A Recent Appraisal of Small-Organic Molecules as Anti-Alzheimer's Agents
Han_2022_Insect.Sci__ Co-CRISPR: a valuable toolkit for mutation enrichment in the gene editing of Spodoptera frugiperda
Hatzmann_2022_Adipocyte__ Dipeptidyl peptidase-4 cell surface expression marks an abundant adipose stem\/progenitor cell population with high stemness in human white adipose tissue
He_2022_Genes.(Basel)_13_ Detoxification Gene Families at the Genome-Wide Level of Rhus Gall Aphid Schlechtendalia chinensis
Hejazi_2022_Chem.Biodivers__ Synthesis, Docking Study and Biological Evaluation of Amide-Based Soluble Epoxide Hydrolase Inhibitors with Novel Secondary Pharmacophore of Pyrimidin-2-ol
Hussain_2022_Molecules_27_6087 Multipotent Cholinesterase Inhibitors for the Treatment of Alzheimer's Disease: Synthesis, Biological Analysis and Molecular Docking Study of Benzimidazole-Based Thiazole Derivatives
Ivanov_2022_Biosensors.(Basel)_12_ Flow-Through Acetylcholinesterase Sensor with Replaceable Enzyme Reactor
Kaabel_2022_ChemSusChem__ Solid-state Enzymatic Hydrolysis of Mixed PET-Cotton Textiles
Kayili_2022_J.Proteomics_267_104700 Site-specific N-glycosylation analysis of human thyroid thyroglobulin by mass spectrometry-based Glyco-analytical strategies
Kim_2022_Trials_23_813 A single-center, randomized, parallel design study to evaluate the efficacy of donepezil in improving visuospatial abilities in patients with mild cognitive impairment using eye-tracker: the COG-EYE study protocol for a phase II trial
Koca-Caliskan_2022_Chem.Biodivers__ Synthesis and Characterization of Copper-Nanoflowers with the Utilization of Medicinal Plant Extracts for Enhanced Various Enzyme Inhibitory Activities
Kroustkova_2022_Phytochemistry__113439 Structural analysis of unusual alkaloids isolated from Narcissus pseudonarcissus cv. Carlton
Kuznetsova_2022_Pharmaceutics_14_ Oxime Therapy for Brain AChE Reactivation and Neuroprotection after Organophosphate Poisoning
Lee_2022_Environ.Toxicol.Chem__ Validation of an SH-SY5Y Cell-Based Acetylcholinesterase Inhibition Assay for Water Quality Assessment
Lin_2022_Biomed.Res.Int_2022_7483911 Screening Potential Diagnostic Biomarkers for Age-Related Sarcopenia in the Elderly Population by WGCNA and LASSO
Lorusso_2022_Chemosphere__136594 Carbon nanomaterial functionalization with pesticide-detoxifying carboxylesterase
Lu_2022_Anal.Chim.Acta_1229_340383 Dual-mode colorimetric-photothermal sensing platform of acetylcholinesterase activity based on the peroxidase-like activity of Fe-N-C nanozyme
Lu_2022_Neurosci.Lett_789_136879 Molecular mechanisms by which targeted muscle reinnervation improves the microenvironment of spinal cord motor neurons and target muscles
Ma_2022_Microorganisms_10_ Isolation and Identification of Efficient Malathion-Degrading Bacteria from Deep-Sea Hydrothermal Sediment
Matsuyama_2022_Clin.Pediatr.Endocrinol_31_185 Goiter in a 6-year-old patient with novel thyroglobulin gene variant (Gly145Glu) causing intracellular thyroglobulin transport disorder: Correlation between goiter size and the free T3 to free T4 ratio
Miklankova_2022_J.Diabetes.Res_2022_4587907 The Different Insulin-Sensitising and Anti-Inflammatory Effects of Palmitoleic Acid and Oleic Acid in a Prediabetes Model
Mishra_2022_J.Food.Biochem__e14436 Neuroprotective potential of ferulic acid against cyclophosphamide-induced neuroinflammation and behavioral changes
Nagaroor_2022_Biotechnol.Genet.Eng.Rev__1 An overview of mammalian and microbial hormone-sensitive lipases (lipolytic family IV): biochemical properties and industrial applications
Nakagawa_2022_Ther.Drug.Monit__ Associations among plasma concentrations of edoxaban and M-4, prothrombin time, and the SLCO1B1*15 haplotype in patients with non-valvular atrial fibrillation
Ogunsuyi_2022_J.Biomol.Struct.Dyn__1 Phytochemicals from African eggplants (Solanum macrocarpon L) and Black nightshade (Solanum nigrum L) leaves as acetylcholinesterase inhibitors: an in-silico study
Sabbir_2022_J.Alzheimers.Dis__ Loss of Cholinergic Receptor Muscarinic 1 (CHRM1) Protein in the Hippocampus and Temporal Cortex of a Subset of Individuals with Alzheimer's Disease, Parkinson's Disease, or Frontotemporal Dementia: Implications for Patient Survival
Sharma_2022_Drug.Dev.Res__ Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors
Tanase_2022_Plants.(Basel)_11_ Biological Activity of Bark Extracts from Northern Red Oak (Quercus rubra L.): An Antioxidant, Antimicrobial and Enzymatic Inhibitory Evaluation
Tian_2022_Pharmaceuticals.(Basel)_15_ Antioxidant, Antibacterial, Enzyme Inhibitory, and Anticancer Activities and Chemical Composition of Alpinia galanga Flower Essential Oil
Travers-Lesage_2022_Expert.Opin.Drug.Discov_17_325 Advances in prodrug design for Alzheimer's disease: the state of the art
Ueno_2022_World.J.Gastroenterol_28_3410 Risk factors and diagnostic biomarkers for nonalcoholic fatty liver disease-associated hepatocellular carcinoma: Current evidence and future perspectives
Uzairu_2022_Heliyon_8_e10613 Kinetics and computational study of butyrylcholinesterase inhibition by methylrosmarinate: relevance to Alzheimer's disease treatment
Vang_2022_Anal.Biochem__114919 Enzyme kinetics by real-time quantitative NMR (qNMR) spectroscopy with progress curve analysis
Varkonyi_2022_Int.J.Mol.Sci_23_ Investigation of Anxiety- and Depressive-like Symptoms in 4- and 8-Month-Old Male Triple Transgenic Mouse Models of Alzheimer's Disease
Venthur_2022_Front.Physiol_13_989006 Analysis of glutathione-S-transferases from larvae of Galleria mellonella (Lepidoptera, Pyralidae) with potential alkaloid detoxification function
Wang_2022_Phytomedicine_102_154154 Polygoni multiflori radix extracts inhibit SARS-CoV-2 pseudovirus entry in HEK293T cells and zebrafish larvae
Xu_2022_Int.J.Mol.Sci_23_ Juniperus sabina L. as a Source of Podophyllotoxins: Extraction Optimization and Anticholinesterase Activities
Yan_2022_Environ.Sci.Ecotechnol_12_100198 Organophosphate esters cause thyroid dysfunction via multiple signaling pathways in zebrafish brain
Yang_2022_Anal.Methods__ Acetylcholinesterase-Cu(3)(PO(4))(2) hybrid nanoflowers for electrochemical detection of dichlorvos using square-wave voltammetry
Ye_2022_World.J.Clin.Cases_10_8186 Short-term prognostic factors for hepatitis B virus-related acute-on-chronic liver failure
Yigit_2022_Arch.Pharm.(Weinheim)__e2200348 Phthalimide-tethered imidazolium salts: Synthesis, characterization, enzyme inhibitory properties, and in silico studies
Yuen_2022_Molecules_27_ Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture
Zampolli_2022_Microorganisms_10_ Genome-Based Exploration of Rhodococcus Species for Plastic-Degrading Genetic Determinants Using Bioinformatic Analysis
Zhan_2022_Biology.(Basel)_11_ Integrative Analysis of Transcriptome and Metabolome Reveals Molecular Responses in Eriocheir sinensis with Hepatopancreatic Necrosis Disease
Zonnchen_2022_New.Phytol__ EDS1 complexes are not required for PRR responses and execute TNL-ETI from the nucleus in Nicotiana benthamiana
Admassie_2022_Biomed.Res.Int_2022_6778352 In Vitro Evaluation of Extracellular Enzyme Activity and Its Biocontrol Efficacy of Bacterial Isolates from Pepper Plants for the Management of Phytophthora capsici
Aktas_2022_Heliyon_8_e10625 The palladium-based complexes bearing 1,3-dibenzylbenzimidazolium with morpholine, triphenylphosphine, and pyridine derivate ligands: synthesis, characterization, structure and enzyme inhibitions
Albayrak_2022_Chem.Biodivers__ Anticholinesterase compounds from endemic Prangos uechtritzii
Andrade_2022_J.Clin.Psychiatry_83_22f14668 Reconsideration of the Benefits of Pharmacological Interventions for the Attenuation of the Cognitive Adverse Effects of Electroconvulsive Therapy
Anwar_2022_Front.Plant.Sci_13_988352 A comprehensive phytochemical, biological, and toxicological studies of roots and aerial parts of Crotalaria burhia Buch.-Ham: An important medicinal plant
Atmaca_2022_J.Biomol.Struct.Dyn__1 A safe alternative synthesis of primary carbamates from alcohols\; in vitro and in silico assessments as an alternative acetylcholinesterase inhibitors
Bains_2022_Eur.J.Pharmacol__175316 Anti-inflammatory effects of ellagic acid and vanillic acid against quinolinic acid-induced rat model of Huntington's disease by targeting IKK-NF-B pathway
Bottermann_2022_Basic.Res.Cardiol_117_48 Cardiomyocyte p38 MAPKalpha suppresses a heart-adipose tissue-neutrophil crosstalk in heart failure development
Casedas_2022_Front.Pharmacol_13_1009868 Evaluation of two different Cannabis sativa L. extracts as antioxidant and neuroprotective agents
Chen_2022_Environ.Sci.Technol__ Defining the Chemical Additives Driving In Vitro Toxicities of Plastics
Chen_2022_Food.Res.Int_161_111799 Intact aleurone cells limit the hydrolysis of endogenous lipids in wheat bran during storage
Cho_2022_J.Vet.Sci_23_e79 Correlating two-dimensional shear wave elastography of acute pancreatitis with Spec cPL in dogs
Costa_2022_Food.Res.Int_161_111851 Enzymatic synthesis of ascorbyl oleate and evaluation of biological activities
Cuthbert_2022_Front.Mol.Biosci_9_866854 Functional and Structural Diversity of Bacterial Contact-Dependent Growth Inhibition Effectors
Cuzziol_2022_Chemosphere__136554 Comparative assessment of individual and mixture chronic toxicity of glyphosate and glufosinate ammonium on amphibian tadpoles: A multibiomarker approach
Dabire_2022_BMC.Microbiol_22_228 Assessment of probiotic and technological properties of Bacillus spp. isolated from Burkinabe Soumbala
Dey_2022_J.Med.Case.Rep_16_354 Acute pancreatitis in pregnancy following COVID-19 vaccine: a case report
Dorman_2022_Vertex_33_62 [Do we treat dementia of the Alzheimer type or Alzheimer's disease? Anti-dementia drugs in the era of biomarkers]
E_2022_J.Pharm.Sci__ Identification and quantification of a problematic host cell protein to support therapeutic protein development
Ebright_2022_Alzheimers.Res.Ther_14_152 Eicosanoid lipidome activation in post-mortem brain tissues of individuals with APOE4 and Alzheimer's dementia
El Said_2022_Egypt.J.Immunol_29_134 Detection of ERG11 gene in fluconazole resistant urinary candida isolates
Fashe_2022_Front.Pharmacol_13_1004010 Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes
Feng_2022_Front.Pediatr_10_1003887 Screening for Wilson's disease in acute liver failure: A new scoring system in children
Fukuda_2022_J.Alzheimers.Dis__ Anti-Dementia Drug Persistence Following Donepezil Initiation Among Alzheimer's Disease Patients in Japan: LIFE Study
Fuloria_2022_Front.Pharmacol_13_830103 Biological activities of meroterpenoids isolated from different sources
Gao_2022_Parasit.Vectors_15_353 Identification of differentially expressed genes based on antennae RNA-seq analyses in Culex quinquefasciatus and Culex pipiens molestus
Gromek_2022_J.Am.Geriatr.Soc__ Anticholinergic co-prescribing in nursing home residents using cholinesterase inhibitors: potential deprescribing cascade
Guo_2022_J.Alzheimers.Dis__ The Therapeutic Effects of Seven Lycophyte Compounds on Cell Models of Alzheimer's Disease
Guo_2022_Aging.(Albany.NY)_14_ Novel small molecular compound 2JY-OBZ4 alleviates AD pathology in cell models via regulating multiple targets
Haenen_2022_J.Med.Case.Rep_16_356 Painful lower limb nodules as first symptom of resectable pancreatic acinar cell cancer: a case report
Hammid_2022_Drug.Metab.Dispos__ Activity and expression of carboxylesterases and arylacetamide deacetylase in human ocular tissues
Hannan_2022_Evid.Based.Complement.Alternat.Med_2022_1015310 Protective Mechanisms of Nootropic Herb Shankhpushpi (Convolvulus pluricaulis) against Dementia: Network Pharmacology and Computational Approach
Hayat_2022_Pak.J.Pharm.Sci_35_1191 Phytochemical, enzymatic and biological studies of root extracts of Farsetia hamiltonii Royle
Helleckes_2022_Biotechnol.Bioeng__ Explore or exploit? A model-based screening strategy for PETase secretion by Corynebacterium glutamicum
Hitge_2022_Bioorg.Med.Chem_73_117030 Isatoic anhydrides as novel inhibitors of monoamine oxidase
Hook_2022_BMC.Geriatr_22_783 Anti-cholinergic drug burden in patients with dementia increases after hospital admission: a multicentre cross-sectional study
Huang_2022_Org.Lett__ Enantioselective Total Synthesis of (+)-Sieboldine A and Analogues Thereof
Ireland_2022_Arch.Toxicol__ Bioactivation and detoxification of organophosphorus pesticides in freshwater planarians shares similarities with humans
Jiang_2022_Gen.Physiol.Biophys_41_365 Integrated bioinformatics and machine learning strategies reveal PRDX6 as the key ferroptosis-associated molecular biosignature of heart failure
Jimoh_2022_Chem.Biol.Interact_367_110196 Diphenyl diselenide modulates antioxidant status, inflammatory and redox-sensitive genes in diesel exhaust particle-induced neurotoxicity
Kachhadia_2022_Arch.Microbiol_204_665 Cloning and characterization of Aiia, an acylhomoserine lactonase from Bacillus cereus RC1 to control soft rot causing pathogen Lelliottia amnigena RCE
Kang_2022_J.Med.Food__ The Aqueous Extract of Humulus japonicus Ameliorates Cognitive Dysfunction in Alzheimer's Disease Models via Modulating the Cholinergic System
Ki_2022_Biochem.Biophys.Res.Commun_631_124 Structural and biochemical analysis of the GDSL-family esterase CJ0610C from Campylobacter jejuni
Kim_2022_JAMA.Netw.Open_5_e2234221 Synergistic Associations of PNPLA3 I148M Variant, Alcohol Intake, and Obesity With Risk of Cirrhosis, Hepatocellular Carcinoma, and Mortality
Knight_2022_Int.J.Epidemiol__ Borrowing strength from clinical trials in analysing longitudinal data from a treated cohort: investigating the effectiveness of acetylcholinesterase inhibitors in the management of dementia
Lakra_2022_In.Silico.Pharmacol_10_18 Pharmacophore based virtual screening of cholinesterase inhibitors: search of new potential drug candidates as antialzheimer agents
Li_2022_Med.Oncol_39_250 PRDX6 knockout restrains the malignant progression of intrahepatic cholangiocarcinoma
Dos Santos Correia_2022_Chem.Biodivers__ Synthesis of esters containing cinnamoyl motif with potential larvicide action: A computational, ecotoxicity and in vitro cytotoxicity assessments
Liu_2022_Sci.Rep_12_16609 Independent association of Lp(a) with platelet reactivity in subjects without statins or antiplatelet agents
Liu_2022_Front.Chem_10_996641 An artificial self-assembling peptide with carboxylesterase activity and substrate specificity restricted to short-chain acid p-nitrophenyl esters
Loewenthal_2022_Anal.Chem__ Monitoring the Activity and Inhibition of Cholinesterase Enzymes using Single-Walled Carbon Nanotube Fluorescent Sensors
Luo_2022_Horm.Metab.Res_54_686 Associations of PNPLA3 rs738409 Polymorphism with Plasma Lipid Levels: A Systematic Review and Meta-Analysis
Ma_2022_Acta.Neurobiol.Exp.(Wars)_82_389 Isorhapontigenin prevents beta-amyloid-associated cognitive impairments through activation of the PI3K\/AKT\/GSK-3beta pathway
Martyniuk_2022_Ecotoxicology__ Stress responses of bivalve mollusc Unio tumidus from two areas to ibuprofen, microplastic and their mixture
Merciecca_2022_Sci.Rep_12_16968 Role of Klebsiella pneumoniae Type VI secretion system (T6SS) in long-term gastrointestinal colonization
Naseem_2022_Arch.Pharm.(Weinheim)__e2200356 Synthesis and evaluation of novel xanthene-based thiazoles as potential antidiabetic agents
Navarro-Romero_2022_Elife_11_ Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome
Omeiza_2022_J.Ethnopharmacol__115767 Mechanisms underpinning Carpolobia lutea G. Don ethanol extract's neurorestorative and antipsychotic-like activities in an NMDA receptor antagonist model of schizophrenia
Oyeleye_2022_J.Food.Biochem__e14475 Synergistic cardioprotective ability of co-administration of Moringa supplemented diets and acarbose in diabetic cardiomyopathy involves attenuation of cholinergic, purinergic, monoaminergic, renin-angiotensin system, and antioxidant pathways
Patil_2022_J.Lab.Physicians_14_1 Impact of Serum Amylase Level in the Outcome of Acute Organophosphorus Poisoning: 2-Year Cross-Sectional Study at Rural Teaching Hospital
Peng_2022_Minerva.Med__ Meta-analysis of clinical efficacy and safety of Yangxuenao Granules combined with cholinesterase inhibitors in the treatment of vascular cognitive impairment
Pozzi_2022_Front.Neurosci_16_998224 Predictors of response to acetylcholinesterase inhibitors in dementia: A systematic review
Prada_2022_Cir.Pediatr_35_160 Postoperative hyperlipasemia in perforated appendicitis in children
Raguvaran_2022_Arch.Microbiol_204_650 Larvicidal, antioxidant and biotoxicity assessment of (2-(((2-ethyl-2 methylhexyl)oxy)carbonyl)benzoic acid isolated from Bacillus pumilus against Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus
Remijn-Nelissen_2022_Neuromuscul.Disord__ The effectiveness and side effects of pyridostigmine in the treatment of myasthenia gravis: a cross-sectional study
Riaz_2022_Braz.J.Biol_84_e259506 Acetylcholinesterase inhibitory potential of scorpion venom in Aedes aegypti (Diptera: Culicidae)
Rotimi_2022_Evid.Based.Complement.Alternat.Med_2022_9470178 Zingiber officinale and Vernonia amygdalina Infusions Improve Redox Status in Rat Brain
Saburkina_2022_Anat.Rec.(Hoboken)__ Comparative gross anatomy of epicardiac ganglionated nerve plexi on the human and sheep cardiac ventricles
Saeed_2022_Front.Chem_10_992701 Facile synthesis, crystal structure, biological evaluation, and molecular modeling studies of N-((4-acetyl phenyl) carbamothioyl) pivalamide as the multitarget-directed ligand
Saleem_2022_Evid.Based.Complement.Alternat.Med_2022_3697522 Pharmacological Potential of the Standardized Methanolic Extract of Prunus armeniaca L. in the Haloperidol-Induced Parkinsonism Rat Model
Sayed_2022_Front.Physiol_13_1018795 Immunological and hemato-biochemical effects on catfish (Clarias gariepinus) exposed to dexamethasone
Sepehri_2022_Front.Chem_10_936240 Recent developments in the design and synthesis of benzylpyridinium salts: Mimicking donepezil hydrochloride in the treatment of Alzheimer's disease
Serbest_2022_Acta.Chim.Slov_69_604 Ternary Transition Metal Complexes with an Azo-Imine Ligand and 2,2'-Bipyridine: Characterization, Computational Calculations, and Acetylcholinesterase Inhibition Activities
Sharapov_2022_Biochemistry.(Mosc)_87_839 Effect of Peroxiredoxin 6 on p53 Transcription Factor Level
Shi_2022_Front.Immunol_13_933595 The diagnosis of immune-related pancreatitis disguised as multifocal lesions on MRI by endoscopic ultrasound-guided fine-needle biopsy: A case report
Son_2022_G3.(Bethesda)__ A genetic screen for aldicarb resistance of C. elegans dauer larvae uncovers two alleles of dach-1, a cytochrome P450 gene
Tamagno_2022_Environ.Pollut_314_120301 Household prallethrin-based insecticide toxicity on different C. elegans life stage: A possible sign of Huntington Disease
Taviano_2022_Pharm.Biol_60_1994 Volatile composition, antidiabetic, and anti-obesity potential of Brassica incana leaf and flowering top extracts
Tesser_2022_Chemosphere_309_136664 Biogenic metallic nanoparticles (Ag, TiO(2), Fe) as potential fungicides for agriculture: are they safe for the freshwater mussel Anodontites trapesialis?
Trabelsi_2022_Environ.Toxicol__ The potential adverse effects of acrylamide on the oxidative stress response, fatty acids profile, and histopathological aspect of the Mediterranean Holothuria forskali respiratory tree
Vidal_2022_J.Psychopharmacol__2698811221128963 Pharmaco-fUS in cognitive impairment: Lessons from a preclinical model
Wang_2022_Eur.J.Med.Chem_244_114806 Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease
Wang_2022_Front.Vet.Sci_9_1004841 Tannic acid reduced apparent protein digestibility and induced oxidative stress and inflammatory response without altering growth performance and ruminal microbiota diversity of Xiangdong black goats
Wu_2022_Front.Endocrinol.(Lausanne)_13_982488 Improved liver lipid catabolism and utilization in growth hormone transgenic common carp (Cyprinus carpio L.) through enhanced lipolytic and fatty acid beta-oxidation pathways
Xu_2022_Fitoterapia_163_105327 Chemical constituents from Daphne giraldii and their cytotoxicities and inhibitory activities against acetylcholinesterase
Yamashita_2022_Methods.Enzymol_675_235 Phosphorylation and subcellular localization of human phospholipase A1, DDHD1\/PA-PLA1
Yang_2022_Front.Physiol_13_1015793 Identification and characterization of candidate detoxification genes in Pharsalia antennata Gahan (Coleoptera: Cerambycidae)
Yousefi_2022_Toxicol.Ind.Health__7482337221125954 Organochlorine and organophosphorus pesticides may induce brain cancer through oxidative stress
Yu_2022_Nat.Chem.Biol__ Parallel pathways for serotonin biosynthesis and metabolism in C. elegans
Yu_2022_JHEP.Rep_4_100575 Spleen volume-based non-invasive tool for predicting hepatic decompensation in people with compensated cirrhosis (CHESS1701)
Zhang_2022_World.J.Psychiatry_12_1127 Emerging role of psychosis in Parkinson's disease: From clinical relevance to molecular mechanisms
Akter_2022_Front.Pharmacol_13_1010103 Pomegranate juice fermented by tannin acyl hydrolase and Lactobacillus vespulae DCY75 enhance estrogen receptor expression and anti-inflammatory effect
Li_2022_Mol.Psychiatry__ Genome-wide association study meta-analysis of suicide death and suicidal behavior
Liu_2022_Int.J.Mol.Sci_23_10997 Valorization of Polyethylene Terephthalate to Muconic Acid by Engineering Pseudomonas Putida
Rosli_2022_Microorganisms_10_ Structure Prediction and Characterization of Thermostable Aldehyde Dehydrogenase from Newly Isolated Anoxybacillus geothermalis Strain D9
Walker_2022_Cells_11_ Diverging Effects of Adolescent Ethanol Exposure on Tripartite Synaptic Development across Prefrontal Cortex Subregions
Han_2022_Medicine.(Baltimore)_101_e29689 Plasma exchange therapy for familial chylomicronemia syndrome in infant: A case report
Thirumal Kumar_2022_Adv.Protein.Chem.Struct.Biol_132_89 Computational and structural investigation of Palmitoyl-Protein Thioesterase 1 (PPT1) protein causing Neuronal Ceroid Lipofuscinoses (NCL)
Ahmed_2022_Int.J.Neurosci__1 Pharmacological Evaluation of Newly Synthesized Benzimidazole Derivative for Anti-Alzheimer Potential
Ajayi_2022_J.Biochem.Mol.Toxicol__e23252 Aggressive-like behaviour and neurocognitive impairment in alcohol herbal mixture-fed mice are associated with increased neuroinflammation and neuronal apoptosis in the prefrontal cortex
Amenyogbe_2022_Sci.Rep_12_17410 Effects of autochthonous strains mixture on gut microbiota and metabolic profile in cobia (Rachycentron canadum)
Asitok_2022_World.J.Microbiol.Biotechnol_38_235 Intracellular-to-extracellular localization switch of acidic lipase in Enterobacter cloacae through multi-objective medium optimization: aqueous two-phase purification and activity kinetics
Baek_2022_Signal.Transduct.Target.Ther_7_367 Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus
Borovsky_2022_Arch.Insect.Biochem.Physiol__e21977 Cloning and characterization of Aedes aegypti juvenile hormone epoxide hydrolases (JHEHs)
Borowiecki_2022_Int.J.Mol.Sci_23_ Chemoenzymatic Synthesis of Optically Active Ethereal Analog of iso-Moramide-A Novel Potentially Powerful Analgesic
Botelho_2022_Int.J.Mol.Sci_23_ Studies on the Phytochemical Profile of Ocimum basilicum var. minimum (L.) Alef. Essential Oil, Its Larvicidal Activity and In Silico Interaction with Acetylcholinesterase against Aedes aegypti (Diptera: Culicidae)
Chaichompoo_2022_Phytochemistry_205_113473 Alkaloids with cholinesterase inhibitory activities from the bulbs of Crinum amabile Donn ex Ker Gawl
Chen_2022_Anal.Chim.Acta_1232_340495 Highly selective SERS detection of acetylcholinesterase in human blood based on catalytic reaction
Codony_2022_J.Med.Chem_65_13660 Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
Cvetkovska_2022_J.Neurosci__ Neurexin-beta Mediates the Synaptogenic Activity of Amyloid Precursor Protein
Dong_2022_Bioorg.Chem_129_106208 Guaiane-type sesquiterpenoids with various ring skeletons from Daphne bholua uncovered by molecular networking and structural revisions of previously reported analogues
Ekinci_2022_North.Clin.Istanb_9_311 Neostigmine versus sugammadex on post-operative recovery following bariatric surgery
Fernandez-Acosta_2022_BMC.Biol_20_233 orsai, the Drosophila homolog of human ETFRF1, links lipid catabolism to growth control
Gao_2022_Front.Microbiol_13_1017804 Cymbopogon citratus (DC.) Stapf aqueous extract ameliorates loperamide-induced constipation in mice by promoting gastrointestinal motility and regulating the gut microbiota
Girotto_2022_Environ.Sci.Pollut.Res.Int__ Using mesocosms to evaluate the impacts of pasture intensification and pasture-sugarcane conversion on tadpoles in Brazil
Guo_2022_Nat.Metab_4_1352 Cdo1 promotes PPARgamma-mediated adipose tissue lipolysis in male mice
Hameed_2022_Future.Med.Chem__ Efficient one-pot synthesis of arylated pyrazole-fused pyran analogs: as leads to treating diabetes and Alzheimer's disease
Hamide_2022_Chem.Biodivers__ Benzimidazolium Salts Containing Trifluoromethoxybenzyl: Synthesis, Characterization, Crystal Structure, Molecular Docking Studies and Enzymes Inhibitory Properties
Hasnaoui_2022_Int.J.Mol.Sci_23_ Purification, Biochemical and Kinetic Characterization of a Novel Alkaline sn-1,3-Regioselective Triacylglycerol Lipase from Penicilliumcrustosum Thom Strain P22 Isolated from Moroccan Olive Mill Wastewater
Hecht_2022_MAbs_14_2135183 Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms
Huang_2022_Nutrients_14_ Maternal Low-Protein Diet during Puberty and Adulthood Aggravates Lipid Metabolism of Their Offspring Fed a High-Fat Diet in Mice
Huang_2022_Clin.Chim.Acta__ Familial chylomicronemia syndrome caused by compound heterozygous mutation of lipoprotein lipase gene: a case report and review of literature
Ireland_2022_Front.Toxicol_4_948455 Differences in neurotoxic outcomes of organophosphorus pesticides revealed via multi-dimensional screening in adult and regenerating planarians
Kotzbeck_2022_J.Lipid.Res__100305 Rosiglitazone reverses inflammation in epididymal white adipose tissue in hormone-sensitive lipase-knockout mice
Kumar_2022_Curr.Top.Med.Chem__ Recent advances in the development of nitrogen-containing heterocyclic Anti-Alzheimer's agents
Kuo_2022_Am.J.Case.Rep_23_e937128 Case Report: Successful Reversal of Residual Block with Sugammadex in a Patient Not Known to Have Myasthenia Gravis
Lemoui_2022_Nat.Prod.Res__1 LC-MS profile, in vitro acetylcholinesterase inhibitory, antibacterial and hemostatic properties of Ranunculus bullatus extract
Li_2022_Molecules_27_6336 Phytochemical Properties and In Vitro Biological Activities of Phenolic Compounds from Flower of Clitoria ternatea L
Li_2022_Drug.Des.Devel.Ther_16_3557 Semaglutide May Alleviate Hepatic Steatosis in T2DM Combined with NFALD Mice via miR-5120\/ABHD6
Lin_2022_Neurobiol.Dis_174_105887 Alzheimer's disease\/dementia-associated brain pathology in aging DPP6-KO mice
Liu_2022_Int.J.Mol.Sci_23_11716 Genes, Structural, and Biochemical Characterization of Four Chlorophyllases from Solanum lycopersicum
Mena_2022_Environ.Sci.Pollut.Res.Int__ Biotransformation and oxidative stress responses in fish (Astyanax aeneus) inhabiting a Caribbean estuary contaminated with pesticide residues from agricultural runoff
Mlakic_2022_Molecules_27_ Resveratrol-Maltol and Resveratrol-Thiophene Hybrids as Cholinesterase Inhibitors and Antioxidants: Synthesis, Biometal Chelating Capability and Crystal Structure
Mu_2022_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_286_122021 Glutathione-modified graphene quantum dots as fluorescent probes for detecting organophosphorus pesticide residues in Radix Angelica Sinensis
Muthukumaravel_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109492 Potential biomarker of phenol toxicity in freshwater fish C. mrigala: Serum cortisol, enzyme acetylcholine esterase and survival organ gill
Nguyen_2022_Int.J.Mol.Sci_23_ Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women
Olajide_2022_Front.Aging.Neurosci_14_960314 Inhibiting amyloid beta (1-42) peptide-induced mitochondrial dysfunction prevents the degradation of synaptic proteins in the entorhinal cortex
Orhan_2022_Chem.Biodivers__ Evaluation of anti-Alzheimer activity of synthetic coumarins by combination of in vitro and in silico approaches
Paquette_2022_SAGE.Open.Med.Case.Rep_10_2050313X221131865 A case of eruptive xanthomas associated with pregnancy unmasking a G188E heterozygous mutation of the lipoprotein lipase gene: A case report
Park_2022_Cell.Mol.Gastroenterol.Hepatol__ Ethanol and its nonoxidative metabolites promote acute liver injury by inducing ER stress, adipocyte death and lipolysis
Quimque_2022_ACS.Omega_7_36856 Polyoxygenated Cyclohexenes from Uvaria grandiflora with Multi-Enzyme Targeting Properties Relevant in Type 2 Diabetes and Obesity
Ramalho_2022_Curr.Med.Chem__ Assessing the therapeutic and toxicological profile of novel acetylcholinesterase reactivators: value of in silico and in vitro data
Siddiqui_2022_Front.Physiol_13_1018731 Transcriptome analysis reveals differential effects of beta-cypermethrin and fipronil insecticides on detoxification mechanisms in Solenopsis invicta
Singla_2022_Front.Pharmacol_13_994018 Bergenin ameliorates cognitive deficits and neuropathological alterations in sodium azide-induced experimental dementia
Szafran_2022_ACS.Pharmacol.Transl.Sci_5_919 Carboxylesterase 1d Inactivation Augments Lung Inflammation in Mice
Theansun_2022_Bioelectrochemistry_149_108305 Acetylcholinesterase modified inkjet-printed graphene\/gold nanoparticle\/poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) hybrid electrode for ultrasensitive chlorpyrifos detection
Tirkey_2022_Anesth.Essays.Res_16_89 Premedication with Diclofenac and Precurarization with Atracurium on Succinylcholine-Induced Myalgia in Laparoscopic Cholecystectomy: A Double-Blinded Randomized Study
Titov_2022_Molecules_27_ Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity
Tsagkaris_2022_Int.J.Mol.Sci_23_ The In Vitro Inhibitory Effect of Selected Asteraceae Plants on Pancreatic Lipase Followed by Phenolic Content Identification through Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS)
Tsao_2022_Int.J.Mol.Sci_23_ Human Serum Albumin Misfolding in Aging and Disease
Unnisa_2022_Eur.Rev.Med.Pharmacol.Sci_26_7245 Design, in silico study, synthesis and in vitro evaluation of some N5-(1H-pyrazol-3-yl)-3H-benzo[d]imidazole-2,5-diamine derivatives as potential pancreatic lipase inhibitors for anti-obesity activity
Vaidya_2022_CNS.Drugs__ Clinical Effectiveness of Muscarinic Receptor-Targeted Interventions in Neuropsychiatric Disorders: A Systematic Review
Vivesh_2022_Bioorg.Med.Chem.Lett_76_129018 Proline based rationally designed peptide esters against dipeptidyl peptidase-4: Highly potent anti-diabetic agents
Wang_2022_Mol.Psychiatry__ Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism
Wolejko_2022_Int.J.Environ.Res.Public.Health_19_ Chlorpyrifos Occurrence and Toxicological Risk Assessment: A Review
Xu_2022_Biomed.Pharmacother_156_113847 The monoacylglycerol lipase inhibitor, JZL184, has comparable effects to therapeutic hypothermia, attenuating global cerebral injury in a rat model of cardiac arrest
Yang_2022_Int.J.Biochem.Cell.Biol__106316 Notum Leads to Potential Pro-survival of OSCC Through Crosstalk Between Shh and Wnt\/beta-catenin Signaling Via p-GSK3beta
Yu_2022_Chem.Biodivers__ Chemical and bioactivity diversity of 2-(2-phenylethyl)chromones in agarwood: A review
Yu_2022_Fish.Physiol.Biochem__ Fenpropathrin exposure induces neurotoxicity in zebrafish embryos
Zeng_2022_Biomed.Pharmacother_155_113267 Anti-inflammatory and anti-oxidant properties of Ipomoea nil (Linn.) Roth significantly alleviates cigarette smoke (CS)-induced acute lung injury via possibly inhibiting the NF-kappaB pathway
Zhang_2022_Int.J.Mol.Sci_23_11721 PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation
Zhu_2022_J.Multidiscip.Healthc_15_2375 Cholinesterase is a Potential Biomarker with High Accuracy for the Nephrotic Syndrome Diagnosis in Minors
Parthiban_2022_RSC.Adv_12_29253 1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties
Akinyelu_2022_Pharm.Nanotechnol__ Evaluation of the antioxidant, antidiabetic, and anticholinesterase potential of biogenic silver nanoparticles from Khaya grandifoliola
Akram_2022_Mol.Biotechnol__ An Appraisal on Prominent Industrial and Biotechnological Applications of Bacterial Lipases
Althobaiti_2022_Antioxidants.(Basel)_11_ Ethnomedicinal Plants with Protective Effects against Beta-Amyloid Peptide (Abeta)1-42 Indicate Therapeutic Potential in a New In Vivo Model of Alzheimer's Disease
Arslan_2022_Biomolecules_12_ Cholinesterase Deficiency Syndrome-A Pitfall in the Use of Butyrylcholinesterase as a Biomarker for Wilson's Disease
Bakare_2022_Front.Bioinform_2_972529 In silico discovery of biomarkers for the accurate and sensitive detection of Fusarium solani
Bakrim_2022_Antioxidants.(Basel)_11_ Health Benefits and Pharmacological Properties of Stigmasterol
Benchikha_2022_Life.(Basel)_12_ Evaluation of Possible Antioxidant, Anti-Hyperglycaemic, Anti-Alzheimer and Anti-Inflammatory Effects of Teucrium polium Aerial Parts (Lamiaceae)
Cenci_2022_Int.J.Mol.Sci_23_ Genome-Wide Classification and Phylogenetic Analyses of the GDSL-Type Esterase\/Lipase (GELP) Family in Flowering Plants
Chai_2022_Front.Endocrinol.(Lausanne)_13_994944 Effect of dipeptidyl peptidase-4 inhibitors on postprandial glucagon level in patients with type 2 diabetes mellitus: A systemic review and meta-analysis
Dapper_2022_Microbiol.Spectr__e0245622 Leveraging a Fluorescent Fatty Acid Probe to Discover Cell-Permeable Inhibitors of Plasmodium falciparum Glycerolipid Biosynthesis
de Torre_2022_Molecules_27_7100 Anticholinesterase Activity of Selected Medicinal Plants from Navarra Region of Spain and a Detailed Phytochemical Investigation of Origanum vulgare L. ssp. vulgare
Echeverri-Jaramillo_2022_Microorganisms_10_ Towards the Development of Microbial Ecotoxicology Testing Using Chlorpyrifos Contaminated Sediments and Marine Yeast Isolates as a Model
El Azab_2022_Oxid.Med.Cell.Longev_2022_4812993 Amelioration of Age-Related Multiple Neuronal Impairments and Inflammation in High-Fat Diet-Fed Rats: The Prospective Multitargets of Geraniol
Elgendy_2022_Life.(Basel)_12_ Ameliorative Impacts of Wheat Germ Oil against Ethanol-Induced Hepatic and Renal Dysfunction in Rats: Involvement of Anti-Inflammatory, Anti-Apoptotic, and Antioxidant Signaling Pathways
El-Nashar_2022_Pharmaceuticals.(Basel)_15_ Neuroprotective Effect of Artichoke-Based Nanoformulation in Sporadic Alzheimer's Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways
Elsebai_2022_Sci.Rep_12_18351 X-ray crystalographic data, absolute configuration, and anticholinesterase effect of dihydromyricitrin 3-O-rhamnoside
Fayez_2022_Antioxidants.(Basel)_11_ The Antioxidant and Enzyme Inhibitory Potential of n-Hexane-Extracted Oils Obtained from Three Egyptian Cultivars of the Golden Dewdrop Duranta erecta Linn. Supported by Their GC-MS Metabolome Analysis and Docking Studies
Fernandes_2022_Nanomaterials.(Basel)_12_ Liposomal Formulations Loaded with a Eugenol Derivative for Application as Insecticides: Encapsulation Studies and In Silico Identification of Protein Targets
Frick_2022_Plant.Physiol__ A family of methyl esterases converts methyl salicylate to salicylic acid in ripening tomato fruit
Gallorini_2022_ACS.Omega_7_37757 Subcritical Hydrothermal Liquefaction as a Pretreatment for Enzymatic Degradation of Polyurethane
Gao_2022_Insects_13_ Pathogenicity of Beauveria bassiana PfBb and Immune Responses of a Non-Target Host, Spodoptera frugiperda (Lepidoptera: Noctuidae)
Ghezellou_2022_Toxins.(Basel)_14_ Comparative Venom Proteomics of Iranian, Macrovipera lebetina cernovi, and Cypriot, Macrovipera lebetina lebetina, Giant Vipers
Hawash_2022_Sci.Rep_12_18223 In vitro and in vivo assessment of the antioxidant potential of isoxazole derivatives
Honorio_2022_Chem.Biol.Interact__110227 Roles of hybrid donepezil scaffolds as potent human acetylcholinesterase inhibitors using in silico interaction analysis, drug-likeness, and pharmacokinetics prediction
Huang_2022_Microorganisms_10_ Environmental Adaptability and Organic Pollutant Degradation Capacity of a Novel Rhodococcus Species Derived from Soil in the Uninhabited Area of the Qinghai-Tibet Plateau
Hung_2022_Molecules_27_ Acetylcholinesterase Inhibitory Activities of Essential Oils from Vietnamese Traditional Medicinal Plants
Ibrahim_2022_Molecules_27_ Advances in Fungal Phenaloenones-Natural Metabolites with Great Promise: Biosynthesis, Bioactivities, and an In Silico Evaluation of Their Potential as Human Glucose Transporter 1 Inhibitors
Ivanusec_2022_Int.J.Mol.Sci_23_ Rat Group IIA Secreted Phospholipase A(2) Binds to Cytochrome c Oxidase and Inhibits Its Activity: A Possible Episode in the Development of Alzheimer's Disease
Jian_2022_Molecules_27_ High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening
Ju_2022_J.Oleo.Sci_71_1679 Efficient Synthesis of Stearidonic Acid Enriched Triacylglycerol from Ahiflower Seed Oil via a Two-Step Enzyme Reaction
Kainuma_2022_Front.Pharmacol_13_991982 An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer's disease
Khan_2022_Pharmaceuticals.(Basel)_15_1221 Phytochemical Profiling, Antioxidant, Antimicrobial and Cholinesterase Inhibitory Effects of Essential Oils Isolated from the Leaves of Artemisia scoparia and Artemisia absinthium
Khan_2022_Pharmaceuticals.(Basel)_15_1205 Anti-Alzheimer and Antioxidant Effects of Nelumbo nucifera L. Alkaloids, Nuciferine and Norcoclaurine in Alloxan-Induced Diabetic Albino Rats
Kiziltas_2022_Molecules_27_ Sahlep (Dactylorhiza osmanica): Phytochemical Analyses by LC-HRMS, Molecular Docking, Antioxidant Activity, and Enzyme Inhibition Profiles
Knapp_2022_J.Physiol.Pharmacol_73_ Endothelial lipase: regulation and biological function
Krenn_2022_J.Neurol__ The clinical and molecular landscape of congenital myasthenic syndromes in Austria: a nationwide study
Kuentzel_2022_Int.J.Mol.Sci_23_ Dysregulation of Placental Lipid Hydrolysis by High-Fat\/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice
Kurbanova_2022_Microorganisms_10_ Effect of Lactobacteria on Bioactive Peptides and Their Sequence Identification in Mature Cheese
Kuzmina_2022_Toxins.(Basel)_14_ sPLA2 Wobbles on the Lipid Bilayer between Three Positions, Each Involved in the Hydrolysis Process
Lekmine_2022_Antioxidants.(Basel)_11_ Ultrasound-Assisted Extraction, LC-MS\/MS Analysis, Anticholinesterase, and Antioxidant Activities of Valuable Natural Metabolites from Astragalus armatus Willd.: In Silico Molecular Docking and In Vitro Enzymatic Studies
Li_2022_Anim.Biotechnol__1 Overexpression of ATGL impairs lipid droplet accumulation by accelerating lipolysis in goat mammary epithelial cells
Li_2022_Molecules_27_6800 Preparation and Characterization of Magnetic Metal-Organic Frameworks Functionalized by Ionic Liquid as Supports for Immobilization of Pancreatic Lipase
Li_2022_Front.Physiol_13_1016582 A full-length transcriptome and gene expression analysis of three detoxification gene families in a predatory stink bug, Picromerus lewisi
Lin_2022_Int.J.Mol.Sci_23_ The Citrus Flavonoid Nobiletin Downregulates Angiopoietin-like Protein 3 (ANGPTL3) Expression and Exhibits Lipid-Modulating Effects in Hepatic Cells and Adult Zebrafish Models
Mahaman_2022_Nutrients_14_ Moringa Oleifera Alleviates Abeta Burden and Improves Synaptic Plasticity and Cognitive Impairments in APP\/PS1 Mice
Mahnashi_2022_Biomolecules_12_ Isolation, In Vitro and In Silico Anti-Alzheimer and Anti-Inflammatory Studies on Phytosteroids from Aerial Parts of Fragaria ananassa Duch
Manzi_2022_Chemosphere__136984 Theoretical evaluation of the malathion and its chemical derivatives interaction with cytosolic phospholipase A2 from zebrafish
Masson_2022_Molecules_27_ Conformational Stability and Denaturation Processes of Proteins Investigated by Electrophoresis under Extreme Conditions
Matosevic_2022_Pharmaceuticals.(Basel)_15_ Design, Synthesis and Biological Evaluation of Biscarbamates as Potential Selective Butyrylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease
Meghwanshi_2022_Biotechnol.Adv__108054 Archaeal lipolytic enzymes: Current developments and further prospects
Meir_2022_Int.J.Mol.Sci_23_ Lipase Catalyzed Transesterification of Model Long-Chain Molecules in Double-Shell Cellulose-Coated Oil-in-Water Emulsion Particles as Microbioreactors
Milicevic_2022_Molecules_27_ Evaluation of the Key Structural Features of Various Butyrylcholinesterase Inhibitors Using Simple Molecular Descriptors
Mohamed_2022_RSC.Adv_12_29048 Synthesis of MnCoO\/CNT nanoflakes for the photocatalytic degradation of methyl orange dye and the evaluation of their activity against Culex pipiens larvae in the purification of fresh water
Ng_2022_Microbiol.Spectr__e0142221 Characterization of Sphingobacterium sp. Ab3 Lipase and Its Coexpression with LEA Peptides
Papagiouvannis_2022_Molecules_27_ Nipecotic Acid Derivatives as Potent Agents against Neurodegeneration: A Preliminary Study
Pisani_2022_Front.Chem_10_1002547 A twenty-year journey exploring coumarin-based derivatives as bioactive molecules
Quandahor_2022_Plants.(Basel)_11_ Potato (Solanum tuberosum L.) Leaf Extract Concentration Affects Performance and Oxidative Stress in Green Peach Aphids (Myzus persicae (Sulzer)
Ramic_2022_Pharmaceuticals.(Basel)_15_ Synthesis, Biological Evaluation and Machine Learning Prediction Model for Fluorinated Cinchona Alkaloid-Based Derivatives as Cholinesterase Inhibitors
Rants'o_2022_Molecules_27_ Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review
Reiland_2022_Bioorg.Med.Chem.Lett__129037 Selective butyrylcholinesterase inhibition by isatin dimers and 3-indolyl-3-hydroxy-2-oxindole dimers
Sahiner_2022_Polymers.(Basel)_14_ Enhanced Bioactive Properties of Halloysite Nanotubes via Polydopamine Coating
Stasilowicz-Krzemien_2022_Pharmaceutics_14_ Cyclodextrin Derivatives as Promising Solubilizers to Enhance the Biological Activity of Rosmarinic Acid
Studzinska-Sroka_2022_Antioxidants.(Basel)_11_ Is Caperatic Acid the Only Compound Responsible for Activity of Lichen Platismatia glauca within the Nervous System?
Takahashi_2022_Behav.Brain.Res__114175 Donepezil prevents olfactory dysfunction and alpha-synuclein aggregation in the olfactory bulb by enhancing autophagy in zinc sulfate-treated mice
Tao_2022_Front.Pharmacol_13_1015966 Traditional Chinese medicine promotes the control and treatment of dementia
Teleglow_2022_Biology.(Basel)_11_ Effect of Intermittent Hypoxic Training on Selected Biochemical Indicators, Blood Rheological Properties, and Metabolic Activity of Erythrocytes in Rowers
Walker_2022_Metabolites_12_ Oxylipins as Potential Regulators of Inflammatory Conditions of Human Lactation
Wang_2022_Chemosphere_306_135610 Analysis of the performance of the efficient di-(2-ethylhexyl) phthalate-degrading bacterium Rhodococcus pyridinovorans DNHP-S2 and associated catabolic pathways
Wang_2022_Chemosphere__136999 Comparison of developmental toxicity induced by PFOA, HFPO-DA, and HFPO-TA in zebrafish embryos
Weitman_2022_Sci.Rep_12_18078 Synthesis and preliminary biological evaluation of gabactyzine, a benactyzine-GABA mutual prodrug, as an organophosphate antidote
Wu_2022_Anal.Methods__ A novel approach for on-site screening of organophosphorus nerve agents based on DTNB modified AgNPs using surface-enhanced Raman spectrometry
Xiang_2022_Biomolecules_12_ EP-Pred: A Machine Learning Tool for Bioprospecting Promiscuous Ester Hydrolases
Xiao_2022_Biosensors.(Basel)_12_ A Novel Paper-Based Electrochemical Biosensor Based on N,O-Rich Covalent Organic Frameworks for Carbaryl Detection
Xu_2022_Nat.Prod.Res__1 A new quinolone and acetylcholinesterase inhibitors from a sponge-associated fungus Penicillium sp. SCSIO41033
Ye_2022_eNeuro__ Coordinated regulation of CB1 cannabinoid receptors and anandamide metabolism stabilizes network activity during homeostatic downscaling
Ye_2022_Front.Cardiovasc.Med_9_974035 DPP3: From biomarker to therapeutic target of cardiovascular diseases
Yin_2022_Front.Nutr_9_1018733 A preliminary study of the chemical composition and bioactivity of Bombax ceiba L. flower and its potential mechanism in treating type 2 diabetes mellitus using ultra-performance liquid chromatography quadrupole-time-flight mass spectrometry and network pharmacology analysis
Yuan_2022_Molecules_27_ Antibacterial Efficacy and Mechanisms of Curcumin-Based Photodynamic Treatment against Staphylococcus aureus and Its Application in Juices
Zainab_2022_Front.Pharmacol_13_1008182 A study on green synthesis, characterization of chromium oxide nanoparticles and their enzyme inhibitory potential
Zhang_2022_Cardiovasc.Ther_2022_3328574 Biological Properties and Clinical Significance of Lipoprotein-Associated Phospholipase A(2) in Ischemic Stroke
Zhao_2022_ACS.Cent.Sci_8_1424 Cellular Target Deconvolution of Small Molecules Using a Selection-Based Genetic Screening Platform
Abdelhamid_2022_J.AOAC.Int__ Tailoring Two Chemometric Models for Determination of Three Neuromuscular Combined Medications and Application to Spiked Human Plasma
Aissous_2022_Drug.Chem.Toxicol__1 The preventive effects of Centaurea maroccana Ball. extract against oxidative stress induced by cisplatin in mice brains: in vitro and in vivo studies
Albrakati_2022_Environ.Sci.Pollut.Res.Int__ Monosodium glutamate induces cortical oxidative, apoptotic, and inflammatory challenges in rats: the potential neuroprotective role of apigenin
Aliakbarzadeh_2022_Environ.Pollut__120587 Adverse effects of polystyrene nanoplastic and its binary mixtures with nonylphenol on zebrafish nervous system: From oxidative stress to impaired neurotransmitter system
Aliwarga_2022_Int.J.Mol.Sci_23_ Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and Degradation
Aljubiri_2022_Z.Naturforsch.C.J.Biosci__ In vitro acetylcholinesterase, tyrosinase inhibitory potentials of secondary metabolites from Euphorbia schimperiana and Euphorbia balsamifera
Al-Shabrawey_2022_Life.Res.(Auckl)_5_ Hyperhomocysteinemia dysregulates plasma levels of polyunsaturated fatty acids-derived eicosanoids
Asen_2022_Front.Nutr_9_1021893 In vitro inhibition of acetylcholinesterase activity by yellow field pea (Pisum sativum) protein-derived peptides as revealed by kinetics and molecular docking
Atiya_2022_ACS.Omega_7_38361 Mechanistic Insight into the Binding of Huperzine a with Human Transferrin: Computational, Spectroscopic and Calorimetric Approaches
Bashir_2022_J.Clin.Exp.Hepatol_12_1535 Lysosomal Acid Lipase Activity in Non-alcoholic Fatty Liver Disease as a Novel Diagnostic and Therapeutic Target: A Systematic Literature Review of Current Evidence and Future Directions
Cavallero_2022_Life.Sci__121147 Presence, enzymatic activity, and subcellular localization of paraoxonases 1, 2, and 3 in human lung tissues
Couturier_2022_Fly.(Austin)_16_360 HaloTag-based reporters for sparse labeling and cell tracking
da Fonseca_2022_J.Biomol.Struct.Dyn__1 Phytochemical study of Lantana camara flowers, ecotoxicity, antioxidant, in vitro and in silico acetylcholinesterase: molecular docking, MD, and MM\/GBSA calculations
Deng_2022_J.Proteome.Res__ Targeted Metabolomics Study of Human Plasma Revealed Activation of the Cytochrome P450 Epoxygenase\/Epoxide Hydrolase Axis in Patients with IgA Nephropathy
Femy_2022_Arch.Toxicol__ Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method
Flemming_2022_Nat.Rev.Immunol__ Fungal lipase dampens DC response
Guedes_2022_ACS.Omega_7_38752 Methyl Effect on the Metabolism, Chemical Stability, and Permeability Profile of Bioactive N-Sulfonylhydrazones
Hall_2022_Clin.Chem__ Identification of Decreased Butyrylcholinesterase in Sudden Infant Death Syndrome Is, at Best, a First Step Toward Preventive Screening
Hamed_2022_Front.Mol.Neurosci_15_1028364 Neurotoxic effects of different sizes of plastics (nano, micro, and macro) on juvenile common carp (Cyprinus carpio)
Hammouda_2022_RSC.Med.Chem_13_1150 Insights into the medicinal chemistry of heterocycles integrated with a pyrazolo[1,5-a]pyrimidine scaffold
Hoang_2022_Diabetes.Metab.Syndr.Obes_15_3329 The Correlation Between Angiopoietin-Like 3 and Metabolic Markers of Some Lipid and Glucose in Type 2 Diabetes Mellitus Patients at the First Diagnosis
Hollstein_2022_Chemistry__ A triazolium-anchored self-immolative linker enables self-assembly-driven siRNA binding and esterase-induced release
Hou_2022_Toxicol.In.Vitro__105509 The alteration of the expression level of neuropathy target esterase in human neuroblastoma SK-N-SH cells disrupts cellular phospholipids homeostasis
Jiang_2022_Appl.Environ.Microbiol__e0102422 Comparative Genomic Analysis of Carbofuran-Degrading Sphingomonads Reveals the Carbofuran Catabolism Mechanism in Sphingobium sp. Strain CFD-1
Knorr_2022_Sci.Rep_12_18565 Protection of insect neurons by erythropoietin\/CRLF3-mediated regulation of pro-apoptotic acetylcholinesterase
Kose_2022_Turk.J.Med.Sci_52_1075 Could lysosomal acid lipase enzyme activity be used for clinical follow-up in cryptogenic cirrhosis?
Lamrani_2022_Curr.Comput.Aided.Drug.Des__ Hydroxycoumarins and some flavonoids from Pistacia atlantica Desf. as multi-targets inhibitors for Alzheimer's disease: Molecular docking and ADMET studies
Lauletta_2022_Neurol.Sci__ Distal upper limb involvement in myasthenia-myositis association
Lin_2022_3.Biotech_12_341 Lactobacillus delbrueckii subsp. bulgaricus strain TCI904 reduces body weight gain, modulates immune response, improves metabolism and anxiety in high fat diet-induced obese mice
Meier-Stephenson_2022_Alzheimers.Dement.(N.Y)_8_e12283 Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites
Minassa_2022_Toxicology_482_153357 Intermittent exposure to chlorpyrifos results in cardiac hypertrophy and oxidative stress in rats
Osmaniye_2022_J.Biomol.Struct.Dyn__1 Design, synthesis and molecular docking and ADME studies of novel hydrazone derivatives for AChE inhibitory, BBB permeability and antioxidant effects
Pei_2022_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_287_122044 A turn-on fluorescent probe based on ESIPT and AIEE mechanisms for the detection of butyrylcholinesterase activity in living cells and in non-alcoholic fatty liver of zebrafish
Perez-Gonzalez_2022_ACS.Omega_7_38254 Chalcone Derivatives with a High Potential as Multifunctional Antioxidant Neuroprotectors
Pulkrabkova_2022_Arch.Toxicol__ Neurotoxicity evoked by organophosphates and available countermeasures
Rezaie_2022_Cell.Biochem.Funct__ Type 2 diabetes mellitus stimulated pulmonary vascular inflammation and exosome biogenesis in rats
Sen_2022_World.J.Hepatol_14_1844 Natural history and management of liver dysfunction in lysosomal storage disorders
Shi_2022_Transl.Pediatr_11_1717 Novel pathogenic variant combination in LPL causing familial chylomicronemia syndrome in an Asian family and experimental validation in vitro: a case report
Simonsen_2022_Environ.Toxicol.Pharmacol_96_104008 The dichloroacetamide safener benoxacor is enantioselectively metabolized by monkey liver microsomes and cytosol
Song_2022_Phytochemistry__113506 Steroid glycosides from the roots of Marsdenia tenacissima
Tang_2022_Anal.Chem__ Label-Free and Ultrasensitive Detection of Butyrylcholinesterase and Organophosphorus Pesticides by Mn(II)-Based Electron Spin Resonance Spectroscopy with a Zero Background Signal
Tao_2022_Oxid.Med.Cell.Longev_2022_7265486 Epoxyeicosatrienoic Acids Inhibit the Activation of Murine Fibroblasts by Blocking the TGF-beta1-Smad2\/3 Signaling in a PPARgamma-Dependent Manner
van Melis_2022_Neurotoxicol__ Organophosphate insecticides disturb neuronal network development and function via non-AChE mediated mechanisms
Verma_2022_Pharmacol.Res__106531 Therapeutic Potential of Reserpine in Metabolic Syndrome: An Evidence Based Study
Wang_2022_Nat.Commun_13_3987 Probing strigolactone perception mechanisms with rationally designed small-molecule agonists stimulating germination of root parasitic weeds
Wang_2022_Food.Chem_404_134672 Characterization of the synergistic inhibitory effect of cyanidin-3-O-glucoside and catechin on pancreatic lipase
Wislowska-Stanek_2022_Behav.Brain.Res__114185 The role of the dorsal hippocampus in resistance to the development of posttraumatic stress disorder-like behaviours
Xiong_2022_Environ.Toxicol__ Chlorphoxim induces neurotoxicity in zebrafish embryo through activation of oxidative stress
Xu_2022_Kidney.Int__ Association between cholinesterase inhibitors and kidney function decline in patients with Alzheimer's dementia
Xu_2022_J.Agric.Food.Chem__ Identification of Host Molecules Involved in the Proliferation of Nucleopolyhedrovirus in Bombyx mori
Xu_2022_Anal.Bioanal.Chem__ Engineering an Ag\/Au bimetallic nanoparticle-based acetylcholinesterase SERS biosensor for in situ sensitive detection of organophosphorus pesticide residues in food
Yang_2022_Front.Neurol_13_900997 The role of butyrylcholinesterase in the regulation of cognitive dysfunction in minimal hepatic encephalopathy: A potential blood marker of disease evolution
Zhang_2022_Nat.Prod.Res__1 Structurally diverse lignans from Solanum lyratum: chemical evidence for their acetylcholinease inhibitory activity
Zhang_2022_Life.Sci_310_121122 Role of epoxyeicosatrienoic acids in cardiovascular diseases and cardiotoxicity of drugs
Zhong_2022_Bioorg.Chem_130_106224 Novel AP2238-clorgiline hybrids as multi-target agents for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation
Adebayo_2022_Andrologia__e14636 Nutraceutical potential of almond fruits in managing diabetes-related erectile dysfunction: Effect on Nrf-2 level and smooth muscle\/collagen ratio
Adefegha_2022_Andrologia__e14629 Aqueous extract of Massularia acuminata exerts erectogenic effect by modulating critical enzymes and hormones in streptozotocin-induced erectile dysfunction in rats
Alov_2022_Int.J.Mol.Sci_23_ In Silico Identification of Multi-Target Ligands as Promising Hit Compounds for Neurodegenerative Diseases Drug Development
Alvarez-Berbel_2022_Pharmaceutics_14_ Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid- Aggregation and Acetylcholinesterase-Amyloid Interaction
Anajirih_2022_Prostaglandins.Other.Lipid.Mediat__106692 Endocannabinoid hydrolases differentially distribute in platelets and red blood cells and are differentially released by thrombin
Arrahman_2022_Toxins.(Basel)_14_ A Combined Bioassay and Nanofractionation Approach to Investigate the Anticoagulant Toxins of Mamba and Cobra Venoms and Their Inhibition by Varespladib
Ayvazyan_2022_Toxins.(Basel)_14_ The Contribution of Phospholipase A(2) and Metalloproteinases to the Synergistic Action of Viper Venom on the Bioenergetic Profile of Vero Cells
Basli_2022_Nutr.Health__2601060221137104 Pathophysiological mechanism and natural preventive and therapeutic strategies of Alzheimer's disease
Bautista-Aguilera_2022_Molecules_27_ N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases
Behl_2022_Ageing.Res.Rev__101787 AChE as a Spark in the Alzheimer's Blaze - Antagonizing Effect of a Cyclized Variant
Bereda_2022_Cureus_14_e29842 Poisoning by Organophosphate Pesticides: A Case Report
Biswas_2022_Med.Res.Arch_10_ Is Serum Creatine Phosphokinase Level Useful to Predict the Severity of Organophosphate Poisoning?
Cai_2022_J.Econ.Entomol__ Sublethal Effects of Thiamethoxam on Biological Traits and Detoxification Enzyme Activities in the Small Brown Planthopper, Laodelphax striatellus (Falln)
Cartuche_2022_Plants.(Basel)_11_ Chemical and Biological Activity Profiling of Hedyosmum&\;nbsp\;strigosum Todzia Essential Oil, an Aromatic Native Shrub from Southern Ecuador
Chen_2022_Molecules_27_7491 A Sensitive and Selective Colorimetric Method Based on the Acetylcholinesterase-like Activity of Zeolitic Imidazolate Framework-8 and Its Applications
De Beer_2022_Biology.(Basel)_11_ High-Resolution Genetic Mapping Combined with Transcriptome Profiling Reveals That Both Target-Site Resistance and Increased Detoxification Confer Resistance to the Pyrethroid Bifenthrin in the Spider Mite Tetranychus urticae
Di Sanzo_2022_Int.J.Mol.Sci_23_ Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration
Dong_2022_Foods_11_ A Simple Aptamer SERS Sensor Based on Mesoporous Silica for the Detection of Chlorpyrifos
Elkina_2022_Biomolecules_12_ New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones
Farooq_2022_Microorganisms_10_ Green Chemistry Based Synthesis of Zinc Oxide Nanoparticles Using Plant Derivatives of Calotropis gigantea (Giant Milkweed) and Its Biological Applications against Various Bacterial and Fungal Pathogens
Fjeld_2022_Pancreatology__ The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice
Gaonkar_2022_Arch.Microbiol_204_705 Simultaneous purification and characterization of detergent-stable, solvent-tolerant haloextremozymes protease and lipase from Haloferax sp. strain GUBF 2
Gaso-Sokac_2022_Int.J.Mol.Sci_23_ Potential of Vitamin B6 Dioxime Analogues to Act as Cholinesterase Ligands
Greenfield_2022_Int.J.Mol.Sci_23_ Characterization of a Bioactive Peptide T14 in the Human and Rodent Substantia Nigra: Implications for Neurodegenerative Disease
Guimaraes_2022_Int.J.Mol.Sci_23_ Tuning Immobilized Enzyme Features by Combining Solid-Phase Physicochemical Modification and Mineralization
Guzman-Lopez_2022_Int.J.Mol.Sci_23_ CADMA-Chem: A Computational Protocol Based on Chemical Properties Aimed to Design Multifunctional Antioxidants
Halder_2022_Pharm.Res__ Asiatic Acid Fabricated Nanoconstructs to Mitigate Amyloid Beta(1-42) Induced Injury in SH-SY5Y Cells In-Vitro and Ameliorates Cognitive Impairment by Dual Cholinesterase Inhibition and Attenuation of Oxidative Stress In-Vivo
Hassan_2022_Drug.Dev.Res__ In vitro enzymatic evaluation of some pyrazolo[1,5-a]pyrimidine derivatives: Design, synthesis, antioxidant, anti-diabetic, anti-Alzheimer, and anti-arthritic activities with molecular modeling simulation
Hong_2022_Pest.Manag.Sci__ Toxicological and molecular adverse effect of Illicium verum fruit constituents toward Bradysia procera
Hu_2022_J.Org.Chem__ Structural Elucidation and Total Synthesis for the Pair of Unprecedented Polypyridines with Anti-AChE and HIV-1 Protease Activities from Alangium chinense
Javed_2022_Molecules_27_ The Antibacterial and Larvicidal Potential of Bis-(2-Ethylhexyl) Phthalate from Lactiplantibacillus plantarum
Khan_2022_Molecules_27_ Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Studies of Indole Based Thiadiazole Derivatives as Dual Inhibitor of Acetylcholinesterase and Butyrylchloinesterase
Kim_2022_Pharmaceutics_14_ Mouse Pharmacokinetics and In Vitro Metabolism of SH-11037 and SH-11008, Synthetic Homoisoflavonoids for Retinal Neovascularization
Kucherenko_2022_Biomater.Adv_143_213180 Application of zeolites and zeolitic imidazolate frameworks in the biosensor development
Kumar_2022_Mol.Divers__ Exploration of a library of piperonylic acid-derived hydrazones possessing variable aryl functionalities as potent dual cholinesterase and monoamine oxidase inhibitors
Landfors_2022_J.Lipid.Res__100313 Genetic mimicry analysis reveals the specific lipases targeted by the ANGPTL3\/ANGPTL8 complex and ANGPTL4
Li_2022_ACS.Appl.Mater.Interfaces__ Carbon Dot-Anchored Cobalt Oxyhydroxide Composite-Based Hydrogel Sensor for On-Site Monitoring of Organophosphorus Pesticides
Liang_2022_Fish.Shellfish.Immunol__ Identification and characterization of two types of triacylglycerol lipase genes from Neocaridina denticulata sinensis
Liu_2022_Molecules_27_7512 Insight into the Inhibitory Mechanism of Aryl Formyl Piperidine Derivatives on Monoacylglycerol Lipase through Molecular Dynamics Simulations
Liu_2022_Chem.Commun.(Camb)__ An esterase-activatable curcumin prodrug for tumor-targeting therapy
Liu_2022_Comb.Chem.High.Throughput.Screen__ Anti-ischemic effect of monoterpene citronellol on experimental stroke models mediated by proinflammatroy cytokines
Lubkin_2022_Cell.Host.Microbe_30_1503 Candida lipase packs a punch against IL-17
Mahnashi_2022_Metabolites_12_ In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer's Disease
Mani_2022_Molecules_27_ Levetiracetam Ameliorates Doxorubicin-Induced Chemobrain by Enhancing Cholinergic Transmission and Reducing Neuroinflammation Using an Experimental Rat Model and Molecular Docking Study
Marriott_2022_Am.J.Health.Syst.Pharm__ Myasthenia gravis: What does a pharmacist need to know?
Mirza_2022_Molecules_27_ Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Rosmarinus officinalis against Alzheimer's Disease
Mohamed_2022_Curr.Atheroscler.Rep__1 ANGPTL3 as a Drug Target in Hyperlipidemia and Atherosclerosis
Mollica_2022_Antioxidants.(Basel)_11_ A Study on Chemical Characterization and Biological Abilities of Alstonia boonei Extracts Obtained by Different Techniques
Morelli_2022_Molecules_27_ Production of High-Quality Red Fruit Juices by Athermal Membrane Processes
Nunes_2022_Pharmaceutics_14_ Drug Delivery Systems as a Strategy to Improve the Efficacy of FDA-Approved Alzheimer's Drugs
Nuthikattu_2022_Int.J.Mol.Sci_23_ High Glycemia and Soluble Epoxide Hydrolase in Females: Differential Multiomics in Murine Brain Microvasculature
O'Brien_2022_Alzheimers.Res.Ther_14_169 RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia-an international Delphi consensus
Omer_2022_Metabolites_12_ Butin Mitigates Memory Impairment in Streptozotocin-Induced Diabetic Rats by Inhibiting Oxidative Stress and Inflammatory Responses
Oztaskin_2022_Molecules_27_ Synthesis of Novel Bromophenol with Diaryl Methanes-Determination of Their Inhibition Effects on Carbonic Anhydrase and Acetylcholinesterase
Pannu_2022_Turk.J.Emerg.Med_22_192 Changing spectrum of acute poisoning in North India: A hospital-based descriptive study
Prikhodko_2022_Biomedicines_10_ Novel Chromone-Containing Allylmorpholines Induce Anxiolytic-like and Sedative Effects in Adult Zebrafish
Rahman_2022_Insects_13_ Larvicidal and Antifeedant Effects of Copper Nano-Pesticides against Spodoptera&\;nbsp\;frugiperda (J.E. Smith) and Its Immunological Response
Rants'o_2022_PLoS.One_17_e0277363 The in silico and in vitro analysis of donepezil derivatives for Anopheles acetylcholinesterase inhibition
Rao_2022_Aquat.Toxicol_253_106345 Bisphenol AF induces multiple behavioral and biochemical changes in zebrafish (Danio rerio) at different life stages
Rivera-Iniguez_2022_Ann.Hepatol__100874 What do we know about nutrient-based strategies targeting molecular mechanisms associated with obesity-related fatty liver disease?: Running Title: Nutrient-based strategies and NAFLD
Rosales_2022_Int.J.Mol.Sci_23_ In Silico and In Vitro Studies of Benzothiazole-Isothioureas Derivatives as a Multitarget Compound for Alzheimer's Disease
Sadlonova_2022_Gen.Hosp.Psychiatry_79_60 Pharmacologic treatment of delirium symptoms: A systematic review
Salinas_2022_Plants.(Basel)_11_2962 Constituents, Enantiomeric Content, and ChE Inhibitory Activity of the Essential Oil from Hypericum laricifolium Juss. Aerial Parts Collected in Ecuador
Sciskalska_2022_Genes.(Basel)_13_ Importance of Polymorphisms in the Gene of Paraoxonase-1 (SNP rs662) and Apolipoprotein A-I (SNP rs670 and rs5069) in Non-Smoking and Smoking Healthy Subjects and Patients with Acute Pancreatitis
Shaikh_2022_Int.J.Mol.Sci_23_ Palm Oil Derived Tocotrienol-Rich Fraction Attenuates Vascular Dementia in Type 2 Diabetic Rats
Shamkh_2022_Int.J.Mol.Sci_23_ Nontoxic and Naturally Occurring Active Compounds as Potential Inhibitors of Biological Targets in Liriomyza trifolii
Shivaram_2022_Neurol.India_70_1931 Rituximab in Myasthenia Gravis- Experience from a Low- and Middle-Income Country (LMIC) Setting
Silva_2022_Bioorg.Chem_130_106249 New amides derived from sclareolide as anticholinesterase agents
Spohr_2022_Neurochem.Res__ Blueberry Extract Modulates Brain Enzymes Activities and Reduces Neuroinflammation: Promising Effect on Lipopolysaccharide-Induced Depressive-Like Behavior
Stern_2022_Int.J.Mol.Sci_23_ Dual Inhibitors of AChE and BACE-1 for Reducing Abeta in Alzheimer's Disease: From In Silico to In Vivo
Takramah_2022_Health.Sci.Rep_5_e913 The efficacy of pharmacological interventions to improve cognitive and behavior symptoms in people with dementia: A systematic review and meta-analysis
Thang_2022_Pharmaceuticals.(Basel)_15_ Determination of Antioxidant, Cytotoxicity, and Acetylcholinesterase Inhibitory Activities of Alkaloids Isolated from Sophora flavescens Ait. Grown in Dak Nong, Vietnam
Trifan_2022_Plants.(Basel)_11_ Exploring the Artemisia Genus: An Insight into the Phytochemical and Multi-Biological Potential of A. campestris subsp. lednicensis (Spreng.) Greuter & Raab-Straube
Tung_2022_Nutrients_14_ Ascophyllum nodosum and Fucus vesiculosus Extracts Improved Lipid Metabolism and Inflammation in High-Energy Diet-Induced Hyperlipidemia Rats
Ullah_2022_Toxics_10_ Impact of Imidacloprid Resistance on the Demographic Traits and Expressions of Associated Genes in Aphis gossypii Glover
Wang_2022_Anal.Chim.Acta_1235_340536 Sensitive detection of organophosphorus pesticides based on the localized surface plasmon resonance and fluorescence dual-signal readout
Yang_2022_Sci.Total.Environ_858_159883 Effect of thiamethoxam on the behavioral profile alteration and toxicity of adult zebrafish at environmentally relevant concentrations
Yang_2022_Neurosci.Lett_792_136961 Gelsemine relieves the neuropathic pain by down-regulating DPP4 level in rats
Zhang_2022_Insects_13_ Transcriptomic Identification and Expression Profile Analysis of Odorant-Degrading Enzymes from the Asian Corn Borer Moth, Ostrinia furnacalis
Zhang_2022_Anal.Chim.Acta_1235_340540 A far-red\/near-infrared fluorescence probe with large Stokes shift for monitoring butyrylcholinesterase (BChE) in living cells and in vivo
Zhu_2022_BMC.Cardiovasc.Disord_22_481 The impact of ABCB1 and CES1 polymorphisms on the safety of dabigatran in patients with non-valvular atrial fibrillation
Anand_2022_Front.Neurosci_16_1005972 Ameliorative effect of vanillin on scopolamine-induced dementia-like cognitive impairment in a mouse model
Arya_2022_Front.Plant.Sci_13_987986 Green approach for the recovery of secondary metabolites from the roots of Nardostachys Jatamansi (D. Don) DC using microwave radiations: Process optimization and anti-alzheimer evaluation
Bardhi_2022_Expert.Rev.Clin.Pharmacol__ Cannabinoids and drug metabolizing enzymes: potential for drug-drug interactions and implications for drug safety and efficacy
Chellammal_2022_J.Diabetes.Metab.Disord_21_1415 Metformin inhibits cardiometabolic syndrome associated cognitive deficits in high fat diet rats
Cowen_2022_Int.J.Pharm_629_122406 Nanoparticle-induced enhancement of cholinesterase activity in the presence of malathion: A potential nerve agent therapeutic
Dhond_2022_Environ.Sci.Technol__ Advancing Fifth Percentile Hazard Concentration Estimation Using Toxicity-Normalized Species Sensitivity Distributions
Eddahmi_2022_Bioorg.Chem_130_106261 Towards Alzheimer's disease-related targets: One-pot Cu(I)- mediated synthesis of new nitroindazolyltriazoles
Fide_2022_Brain.Topogr__ Effects of Pharmacological Treatments in Alzheimer's Disease: Permutation Entropy-Based EEG Complexity Study
Garbelotti_2022_Food.Chem_405_134939 The feruloyl esterase from Thermobacillus xylanilyticus shows broad specificity for processing pre-biotic feruloylated xylooligosaccharides at high temperatures
Homoud_2022_J.Biomol.Struct.Dyn__1 Synthesis of indole derivatives as Alzheimer inhibitors and their molecular docking study
Hong_2022_Mol.Genet.Metab.Rep_33_100935 Stratification of patients with lysosomal acid lipase deficiency by enzyme activity in dried blood spots
Istratoaie_2022_Medicine.(Baltimore)_101_e31553 Paraoxonase 1 and atrial fibrillation: Is there a relationship?
Jiang_2022_ACS.Nano__ Two-Stage SN38 Release from a Core-Shell Nanoparticle Enhances Tumor Deposition and Antitumor Efficacy for Synergistic Combination with Immune Checkpoint Blockade
Kallingal_2022_Arch.Microbiol_204_713 Divulging the anti-acetylcholinesterase activity of Colletotrichum lentis strain KU1 extract as sustainable AChE active site inhibitors
Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents
Kim_2022_Dement.Neurocogn.Disord_21_107 Need for an Update for the Guideline for the Management of Mild Cognitive Impairment
Kontchou_2022_Sci.Total.Environ__160185 Pollutant load and ecotoxicological effects of sediment from stormwater retention basins to receiving surface water on Lumbriculus variegatus
Li_2022_ACS.Chem.Neurosci__ Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease
Li_2022_Biosens.Bioelectron_220_114890 Portable hydrogel test kit integrated dual-emission coordination polymer nanocomposite for on-site detection of organophosphate pesticides
Ma_2022_World.J.Microbiol.Biotechnol_39_17 Characterization of feruloyl esterases from Pecoramyces sp. F1 and the synergistic effect in biomass degradation
Martins_2022_Environ.Sci.Pollut.Res.Int__ Biochemical responses, feeding and survival in the solitary bee Osmia bicornis following exposure to an insecticide and a fungicide alone and in combination
Nafea_2022_Naunyn.Schmiedebergs.Arch.Pharmacol__ Leflunomide abrogates neuroinflammatory changes in a rat model of Alzheimer's disease: the role of TNF-alpha\/NF-B\/IL-1 axis inhibition
Nayak_2022_Appl.Biochem.Biotechnol__ Histopathological and Biochemical Changes in the Gills of Anabas testudineus on Exposure to Polycyclic Aromatic Hydrocarbon Naphthalene
Neylon_2022_J.Dev.Biol_10_ Organophosphate Insecticide Toxicity in Neural Development, Cognition, Behaviour and Degeneration: Insights from Zebrafish
Nielsen_2022_Medicine.(Baltimore)_101_e31625 Real-world effects of anti-dementia treatment on mortality in patients with Alzheimers dementia
Nozue_2022_J.Clin.Lipidol__ A case of hyperchylomicronemia associated with GPIHBP1 autoantibodies and fluctuating thyroid autoimmune disease
Owumi_2022_Environ.Toxicol.Pharmacol__104011 Influence of furan and lead co-exposure at environmentally relevant concentrations on neurobehavioral performance, redox-regulatory system and apoptotic responses in rats
Pak_2022_Front.Pharmacol_13_1014840 Yuk-Gunja-Tang attenuates neuronal death and memory impairment via ERK\/CREB\/BDNF signaling in the hippocampi of experimental Alzheimer's disease model
Paradhipta_2022_Anim.Biosci__ Antifungal and carboxylesterase-producing bacteria applied into corn silage still affected the fermented total mixed ration
Phongphut_2022_ACS.Omega_7_39848 Biosensors Based on Acetylcholinesterase Immobilized on Clay-Gold Nanocomposites for the Discrimination of Chlorpyrifos and Carbaryl
Pradeep_2022_Front.Pharmacol_13_1044248 Anticholinesterase activity of Areca Catechu: In Vitro and in silico green synthesis approach in search for therapeutic agents against Alzheimer's disease
Qi_2022_Front.Plant.Sci_13_1020309 Characterization of the anti-AChE potential and alkaloids in Rhizoma Coptidis from different Coptis species combined with spectrum-effect relationship and molecular docking
Saeedi_2022_BMC.Complement.Med.Ther_22_303 Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity
Schmerling_2022_Commun.Biol_5_1254 Identification of fungal lignocellulose-degrading biocatalysts secreted by Phanerochaete chrysosporium via activity-based protein profiling
Shao_2022_Int.J.Biol.Macromol__ Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits
Shen_2022_J.Agric.Food.Chem_70_14817 Effect of Lactobacillus with Feruloyl Esterase-Producing Ability on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice
Song_2022_Ecotoxicol.Environ.Saf_248_114296 The efficacy of Azotobacter chroococcum in altering maize plant-defense responses to armyworm at elevated CO(2) concentration
Spagnuolo_2022_Mol.Neurobiol__ Long-Lasting Impact of Sugar Intake on Neurotrophins and Neurotransmitters from Adolescence to Young Adulthood in Rat Frontal Cortex
Sutar_2022_Appl.Biochem.Biotechnol__ Purification of Lipase from Pseudomonas aeruginosa VSJK R-9 and Its Application in Combination with the Lipolytic Consortium for Bioremediation of Restaurant Wastewater
Swain_2022_Heliyon_8_e11301 Hydrolea zeylanica improves cognitive impairment in high-fat diet fed-streptozotocin-induced diabetic encephalopathy in rats via regulating oxidative stress, neuroinflammation, and neurotransmission in brain
Vanessa_2022_Nat.Prod.Res__1 Synthesis of 1-hydroxy-3-O-substituted xanthone derivatives and their structure-activity relationship on acetylcholinesterase inhibitory effect
Volonte_2022_BMC.Genomics_23_757 Comparative analysis of detoxification-related gene superfamilies across five hemipteran species
Wang_2022_Br.J.Nutr__1 The dysfunction of hormone-sensitive lipase induces lipid deposition and reprogramming of nutrient metabolism
Yuan_2022_Int.J.Biol.Macromol__ A versatile tag for simple preparation of cutinase towards enhanced biodegradation of polyethylene terephthalate
Zhang_2022_Front.Bioeng.Biotechnol_10_1034972 Genetic manipulation of the interconversion between diacylglycerols and triacylglycerols in Rhodosporidium toruloides
Zhou_2022_Braz.J.Med.Biol.Res_55_e12320 Serum levels of IL-12, IL-18, and IL-21 are indicators of viral load in patients chronically infected with HBV
Zhu_2022_World.J.Oncol_13_272 Vincosamide Has a Function for Inhibiting Malignant Behaviors of Hepatocellular Carcinoma Cells
Al_2022_Histochem.Cell.Biol__ Immunohistochemistry for acetylcholinesterase and butyrylcholinesterase in the dorsal motor nucleus of the vagus (DMNV) of formalin-fixed, paraffin-embedded tissue: comparison with reported literature
Bachurin_2022_Int.J.Mol.Sci_23_ Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease
Bateman_2022_Alzheimers.Res.Ther_14_178 Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer's disease
Benslama_2022_J.Genet.Eng.Biotechnol_20_158 Bioinsecticidal activity of actinomycete secondary metabolites against the acetylcholinesterase of the legume's insect pest Acyrthosiphon pisum: a computational study
Chen_2022_Biosensors.(Basel)_12_ Nanoporous ZIF-8 Microparticles as Acetylcholinesterase and Alkaline Phosphatase Mimics for the Selective and Sensitive Detection of Ascorbic Acid Oxidase and Copper Ions
Chen_2022_Antioxidants.(Basel)_11_2299 Reduced Fitness and Elevated Oxidative Stress in the Marine Copepod Tigriopus japonicus Exposed to the Toxic Dinoflagellate Karenia mikimotoi
Dos Santos_2022_Brain.Res.Bull__ Thiazolidin-4-one prevents against memory deficits, increase in phosphorylated tau protein, oxidative damage and cholinergic dysfunction in Alzheimer disease model: comparison with donepezil drug
Edem_2022_Neurotox.Res__ Combined Exposure to Chronic Sleep Deprivation and Caffeine Potentiates Behavioural Deficits by Altering Neurochemical Profile and Synaptophysin Expression in Long-Evans Rats
Fang_2022_Bioresour.Technol__128393 Concurrent production of ferulic acid and glucose from wheat bran by catalysis of a putative bifunctional enzyme
Gholami_2022_Biochem.Biophys.Rep_32_101392 The effect of combination pretreatment of donepezil and environmental enrichment on memory deficits in amyloid-beta-induced Alzheimer-like rat model
Gomes-Copeland_2022_Plants.(Basel)_11_ Hippeastrum stapfianum (Kraenzl.) R.S.Oliveira & Dutilh (Amaryllidaceae) Ethanol Extract Activity on Acetylcholinesterase and PPAR-alpha\/gamma Receptors
Horn_2022_Chem.Biol.Interact__110285 Human HepaRG liver spheroids: cold storage protocol and study on pyridinium oxime-induced hepatotoxicity in vitro
Modeline_2022_Comput.Struct.Biotechnol.J_20_6206 A pilot reverse virtual screening study suggests toxic exposures caused long-term epigenetic changes in Gulf War Illness
Karaca_2022_J.Biochem.Mol.Toxicol__e23255 Vinyl functionalized 5,6-dimethylbenzimidazolium salts: Synthesis and biological activities
Karaytug_2022_J.Biochem.Mol.Toxicol__e23259 Piperazine derivatives with potent drug moiety as efficient acetylcholinesterase, butyrylcholinesterase, and glutathione S-transferase inhibitors
Li_2022_Environ.Toxicol.Pharmacol_97_104016 Bioaccumulation and toxicity of terbuthylazine in earthworms (Eisenia fetida)
Li_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2209149119 VpdC is a ubiquitin-activated phospholipase effector that regulates Legionella vacuole expansion during infection
Liao_2022_Molecules_27_ Exploring the Inhibition of Quercetin on Acetylcholinesterase by Multispectroscopic and In Silico Approaches and Evaluation of Its Neuroprotective Effects on PC12 Cells
Man_2022_Front.Bioeng.Biotechnol_10_1043130 Engineered small extracellular vesicles as a versatile platform to efficiently load ferulic acid via an esterase-responsive active loading strategy
Naito_2022_J.Mass.Spectrom_57_e4895 Quantitative analysis capability of DIUTHAME mass spectrometry verified by acetylcholinesterase enzyme-catalyzed reaction assays
Olasehinde_2022_Inflammopharmacology__ Hibiscus sabdariffa (Roselle) calyx: a systematic and meta-analytic review of memory-enhancing, anti-neuroinflammatory and antioxidative activities
Orabi_2022_Fitoterapia_164_105360 Structural determination and anticholinesterase assay of C-glycosidic ellagitannins from Lawsonia inermis leaves: A study supported by DFT calculations and molecular docking
Piel_2022_Sci.Rep_12_20329 Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning
Pineda-Hernandez_2022_Plants.(Basel)_11_ BIIDXI, a DUF642 Cell Wall Protein That Regulates Pectin Methyl Esterase Activity, Is Involved in Thermotolerance Processes in Arabidopsis thaliana
Polo-Cuadrado_2022_RSC.Adv_12_33032 Design, synthesis, theoretical study, antioxidant, and anticholinesterase activities of new pyrazolo-fused phenanthrolines
Qiao_2022_Neurotox.Res__ Biogenic Selenium Nanoparticles Attenuate Abeta(25-35)-Induced Toxicity in PC12 Cells via Akt\/CREB\/BDNF Signaling Pathway
Rastegari_2022_BMC.Chem_16_106 Phytochemical analysis and anticholinesterase activity of aril of Myristica fragrans Houtt
Safratova_2022_Plants.(Basel)_11_ Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity
Saleem_2022_Metab.Brain.Dis_38_1051 The curative and mechanistic acumen of curcuminoids formulations against haloperidol induced Parkinson's disease animal model
Semenov_2022_Molecules_27_ Novel Uracil-Based Inhibitors of Acetylcholinesterase with Potency for Treating Memory Impairment in an Animal Model of Alzheimer's Disease
Silva_2022_Brain.Res__148175 Animal model of Alzheimer's disease induced by streptozotocin: new insights about cholinergic pathway
Sosnowska_2022_Molecules_27_ The Effect of Different Growth Stages of Black Chokeberry Fruits on Phytonutrients, Anti-Lipase Activity, and Antioxidant Capacity
Souza_2022_Int.J.Mol.Sci_23_ Immobilization of Lipase B from Candida antarctica in Octyl-Vinyl Sulfone Agarose: Effect of the Enzyme-Support Interactions on Enzyme Activity, Specificity, Structure and Inactivation Pathway
Stancu_2022_Insects_13_ Distribution of Insecticide Resistance Genetic Markers in the West Nile Virus Vector Culex pipiens from South-Eastern Romania
Strawa_2022_Molecules_27_ In Vitro Screening for Anti-Acetylcholinesterase and Antioxidant Activities of Hottonia palustris L. Extracts and Their Unusual Flavonoids
Takano_2022_Surg.Today__ The influence of serum cholinesterase levels and sarcopenia on postoperative infectious complications in colorectal cancer surgery
Taomoto_2022_Front.Psychiatry_13_1051067 Case report: Delusional infestation in dementia with Lewy bodies
Torres-Benitez_2022_Molecules_27_ Metabolomic Profiling, Antioxidant and Enzyme Inhibition Properties and Molecular Docking Analysis of Antarctic Lichens
Tsounidi_2022_Anal.Bioanal.Chem__ AChE-based electrochemical biosensor for pesticide detection in vegetable oils: matrix effects and synergistic inhibition of the immobilized enzyme
Turchetti_2022_Front.Microbiol_13_1026102 A genomic approach to analyze the cold adaptation of yeasts isolated from Italian Alps
Wang_2022_Anal.Chem_94_16345 Colorimetric Assay for Acetylcholinesterase Activity and Inhibitor Screening Based on Metal-Organic Framework Nanosheets
Xu_2022_Insects_13_ Resistance Mechanisms of Sitobion miscanthi (Hemiptera: Aphididae) to Malathion Revealed by Synergist Assay
Xu_2022_Molecules_27_7798 Lipase-Catalyzed Phospha-Michael Addition Reactions under Mild Conditions
Yavasoglu_2022_Turkiye.Parazitol.Derg_46_307 Allele Specific Polymerase Chain Reaction (AS-PCR) Assay to Detect Knockdown and Acetylcholinesterase Mutations in Anopheles superpictus
Adorni_2022_Front.Immunol_13_935241 HDL metabolism and functions impacting on cell cholesterol homeostasis are specifically altered in patients with abdominal aortic aneurysm
Ahmad_2022_Eur.J.Pharmacol__175445 Anti-pancreatic lipase and anti-adipogenic effects of 5, 7, 3',4',5' -pentamethoxy and 6, 2',4'-trimethoxy flavone - An In vitro study
Ahmed_2022_Int.J.Biol.Macromol__ A thermotolerant and pH stable rhamnogalacturonan acetylesterase (CtPae12B), a family 12 carbohydrate esterase from Clostridium thermocellum with broad substrate specificity
Bonaca_2022_Eur.Heart.J.Cardiovasc.Pharmacother_8_243 Recombinant human lecithin-cholesterol acyltransferase in patients with atherosclerosis: phase 2a primary results and phase 2b design
Bonaca_2022_Circulation_146_907 Randomized, Placebo-Controlled Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Lecithin Cholesterol Acyltransferase in Acute ST-Segment-Elevation Myocardial Infarction: Results of REAL-TIMI 63B
Cao_2022_Front.Neurol_13_1034243 Promising candidates from drug clinical trials: Implications for clinical treatment of Alzheimer's disease in China
Chen_2022_PLoS.Med_19_e1004124 Association between antidementia medication use and mortality in people diagnosed with dementia with Lewy bodies in the UK: A retrospective cohort study
Chin_2022_Cureus_14_e31065 Conventional Versus New Treatment: Comparing the Effects of Acetylcholinesterase Inhibitors and N-Methyl-D-Aspartate Receptor Antagonist With Aducanumab
Cueni_2022_J.Vet.Intern.Med__ Progression of lipase activity and pancreatic lipase immunoreactivity in dogs hospitalized for acute pancreatitis and correlation with clinical features
Danaei_2022_BMC.Complement.Med.Ther_22_321 The significance of thymoquinone administration on liver toxicity of diazinon and cholinesterase activity\; a recommendation for prophylaxis among individuals at risk
Dong_2022_Sci.Total.Environ__160567 Tissue-specific accumulation, depuration, and effects of perfluorooctanoic acid on fish: Influences of aqueous pH and sex
Elbagoury_2022_Bioorg.Chem_131_106303 Design, synthesis, and metabolite identification of Tamoxifen esterase-activatable prodrugs
Eraky_2022_Int.J.Biol.Macromol__ Ameliorative effects of bromelain on aluminum-induced Alzheimer's disease in rats through modulation of TXNIP pathway
Farkkila_2022_PLoS.One_17_e0277084 PNPLA3 allele frequency has no impact on biliary bile acid composition or disease course in patients with primary sclerosing cholangitis
Fellows_2022_Pestic.Biochem.Physiol_188_105271 Acute toxicity of atrazine, alachlor, and chlorpyrifos mixtures to honey bees
Giorgi_2022_Mol.Pharm_19_4135 Mechanistic Insights into the Activation of Lecithin-Cholesterol Acyltransferase in Therapeutic Nanodiscs Composed of Apolipoprotein A-I Mimetic Peptides and Phospholipids
Goharrostami_2022_Pestic.Biochem.Physiol_188_105220 Effect of thyme essential oil and its two components on toxicity and some physiological parameters in mulberry pyralid Glyphodes pyloalis Walker
Goni Ros_2022_Acta.Clin.Belg_77_970 A novel pathogenic variant in LCAT causing FLD. A case report
Hu_2022_Chem.Asian.J__e202201097 Tuning the Properties of Ester-Based Degradable Polymers by Inserting Epoxides into Poly(E-caprolactone)
Hughes_2022_Crit.Care_26_377 Association between cholinesterase activity and critical illness brain dysfunction
Inak_2022_Pestic.Biochem.Physiol_188_105235 Long-term survey and characterization of cyflumetofen resistance in Tetranychus urticae populations from Turkey
Ito_2022_Sci.Adv_8_eadd1278 Canonical strigolactones are not the major determinant of tillering but important rhizospheric signals in rice
Lal_2022_Indian.J.Microbiol_62_651 Phylogenetic Analyses of Microbial Hydrolytic Dehalogenases Reveal Polyphyletic Origin
Li_2022_JCI.Insight__ Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy
Li_2022_Plant.Commun_3_100303 The strigolactone receptor D14 targets SMAX1 for degradation in response to GR24 treatment and osmotic stress
Li_2022_Anal.Chem__ In Situ Formation of o-Phenylenediamine Cascade Polymers Mediated by Metal-Organic Framework Nanozymes for Fluorescent and Photothermal Dual-Mode Assay of Acetylcholinesterase Activity
Li_2022_Plant.Cell.Rep_41_2089 The strigolactone receptor SlDWARF14 plays a role in photosynthetic pigment accumulation and photosynthesis in tomato
Liu_2022_Plant.Cell_34_3301 Dwarf and High Tillering1 represses rice tillering through mediating the splicing of D14 pre-mRNA
Liu_2022_Food.Chem_406_134506 Monoacylglycerol lipase from marine Geobacillus sp. showing lysophospholipase activity and its application in efficient soybean oil degumming
Ma_2022_Plants.(Basel)_11_ Silencing of MsD14 Resulted in Enhanced Forage Biomass through Increasing Shoot Branching in Alfalfa (Medicago sativa L.)
Markowitz_2022_Med.Cannabis.Cannabinoids_5_199 The Influence of Cannabidiol on the Pharmacokinetics of Methylphenidate in Healthy Subjects
Martinez_2022_ACS.Omega_7_41882 Biodiesel Production from Transesterification with Lipase from Pseudomonas cepacia Immobilized on Modified Structured Metal Organic Materials
Martinez_2022_Plant.Physiol_190_1440 A KARRIKIN INSENSITIVE2 paralog in lettuce mediates highly sensitive germination responses to karrikinolide
Mishra_2022_ACS.Omega_7_43290 Intranasally Co-administered Berberine and Curcumin Loaded in Transfersomal Vesicles Improved Inhibition of Amyloid Formation and BACE-1
Mostofa_2022_Plant.Cell.Physiol__ Karrikin Receptor KAI2 Coordinates Salt Tolerance Mechanisms in Arabidopsis thaliana
Mukherjee_2022_Comput.Biol.Chem_102_107797 Integrated in silico and experimental discovery of trimeric peptide ligands targeting Butyrylcholinesterase
Nessler_2022_BMC.Cardiovasc.Disord_22_521 Associations between myeloperoxidase and paraoxonase-1 and type 2 diabetes in patients with ischemic heart disease
Padhy_2022_Gene__147096 Wide-spread enhancer effect of SNP rs2279590 on regulating epoxide hydrolase-2 and protein tyrosine kinase 2-beta gene expression
Papa_2022_Eur.J.Med.Chem_246_114952 Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions
Parlar_2022_Arch.Pharm.(Weinheim)__e2200519 N-Substituted piperidine-3-carbohydrazide-hydrazones against Alzheimer's disease: Synthesis and evaluation of cholinesterase, beta-amyloid inhibitory activity, and antioxidant capacity
Patel_2022_Indian.J.Microbiol_62_658 Plastic Eating Enzymes: A Step Towards Sustainability
Raghuvanshi_2022_Drug.Dev.Res__ Multitargeted C9-substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics
Rants'o_2022_Parasitol.Int_93_102713 In vitro and in silico analysis of the Anopheles anticholinesterase activity of terpenoids
Schavinski_2022_Mutat.Res.Genet.Toxicol.Environ.Mutagen_883-884_503549 Effects of isolated and combined exposures of Boana curupi (Anura: Hylidae) tadpoles to environmental doses of trichlorfon and ultraviolet radiation
Sera_2022_Medicine.(Baltimore)_101_e31677 Unexpected cholinergic crisis caused by distigmine bromide: A case report
Sharma_2022_J.Basic.Microbiol__ Understanding challenges associated with plastic and bacterial approach toward plastic degradation
Silva_2022_Enzyme.Microb.Technol_163_110166 Immobilization of Thermomyces lanuginosus lipase on a new hydrophobic support (Streamline phenyl): Strategies to improve stability and reusability
Suo_2022_Langmuir__ Surface Modification of Magnetic ZIF-90 Nanoparticles Improves the Microenvironment of Immobilized Lipase and Its Application in Esterification
Suzuki_2022_Front.Plant.Sci_13_843362 A New Series of Strigolactone Analogs Derived From Cinnamic Acids as Germination Inducers for Root Parasitic Plants
Tong_2022_Biosens.Bioelectron_222_114981 Threaded 3D microfluidic paper analytical device-based ratiometric fluorescent sensor for background-free and visual detection of organophosphorus pesticides
Wang_2022_Chem.Biodivers__ Design, Synthesis, Calculation and Biological Activity Studies Based on Privileged Coumarin Derivatives as Multifunctional Anti-AD Lead Compound
Wang_2022_J.Agric.Food.Chem_70_15487 Novel Bisamide Alkaloids Enantiomers from Pepper Roots (Piper nigrum L.) with Acetylcholinesterase Inhibitory and Anti-Neuroinflammatory Effects
Waters_2022_New.Phytol__ Karrikin perception and signalling
Wu_2022_Heliyon_8_e11751 Role of non-neuronal cholinerg