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Year Report for: 2022

Abadia_2022_Sci.Total.Environ_815_152841Hazardous effects of road-side soils on the redox and cholinesterasic homeostasis of mound-building termite (Cornitermes cumulans)
Abbas_2022_Plants.(Basel)_11_Novel Neuroprotective Potential of Bunchosia armeniaca (Cav.) DC against Lipopolysaccharide Induced Alzheimer's Disease in Mice
Abd El-Aziz_2022_Pharmaceuticals.(Basel)_16_Characterization of Orange Peel Extract and Its Potential Protective Effect against Aluminum Chloride-Induced Alzheimer's Disease
Abdalla_2022_Br.J.Pharmacol__Soluble epoxide hydrolase inhibition enhances Specialized Pro-resolving Lipid Mediator production and promotes macrophage plasticity
Abdalla_2022_Inflammopharmacology__Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporomandibular joint
Abdel-Aziz_2022_Arch.Pharm.(Weinheim)__e2200024New pyrimidine/thiazole hybrids endowed with analgesic, anti-inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX-2/sEH dual inhibition
Abdel-Baki_2022_Plant.Foods.Hum.Nutr__Ferocactus herrerae Fruits: Nutritional Significance, Phytochemical Profiling, and Biological Potentials
Abdel-Rasoul_2022_Environ.Sci.Pollut.Res.Int__Respiratory, hepatic, renal, and hematological disorders among adolescent females environmentally exposed to pesticides, Menoufia governorate, Egypt
Abdel-Tawab_2022_PLoS.One_17_e0265184Evaluation of gene expression of PLEKHS1, AADAC, and CDKN3 as novel genomic markers in gastric carcinoma
Abdel_2022_Nat.Prod.Res__1Acetylcholinesterase inhibitors from Conocarpus lancifolius Engl. (Combretaceae)
Abdelghany_2022_Biomarkers__1Neuroprotective role of medicinal plant extracts evaluated in a scopolamine-induced rat model of Alzheimer's disease
Abdelhamid_2022_J.AOAC.Int__Tailoring Two Chemometric Models for Determination of Three Neuromuscular Combined Medications and Application to Spiked Human Plasma
Abderrezag_2022_J.Chromatogr.A_1675_463147One-step sustainable extraction of Silymarin compounds of wild Algerian milk thistle (Silybum marianum) seeds using Gas Expanded Liquids
Abdullah_2022_ACS.Omega_7_32360Synthesis, Characterization, and Enzyme Inhibition Properties of 1,2,4-Triazole Bearing Azinane Analogues
Abed_2022_Molecules_27_Palm Raceme as a Promising Biomass Precursor for Activated Carbon to Promote Lipase Activity with the Aid of Eutectic Solvents
Abi_2022_Int.J.Mol.Sci_23_Treatment of Mouse Sperm with a Non-Catalytic Mutant of PLA2G10 Reveals That PLA2G10 Improves In Vitro Fertilization through Both Its Enzymatic Activity and as Ligand of PLA2R1
Abobakr_2022_Insects_13_Organophosphate Insecticides Resistance in Field Populations of House Flies, Musca domestica L.: Levels of Resistance and Acetylcholinesterase Activity
Abohalaka_2022_Life.Sci__120808Endocannabinoid metabolism inhibition ameliorates ovalbumin-induced allergic airway inflammation and hyperreactivity in Guinea pigs
Aboulthana_2022_Asian.Pac.J.Cancer.Prev_23_287Assessment of the Biological Activities of Egyptian Purslane (Portulaca oleracea) Extract after Incorporating Metal Nanoparticles, in Vitro and in Vivo Study
Abraham_2022_Appl.Biochem.Biotechnol__1In Silico Molecular Docking Approach Against Enzymes Causing Alzheimer's Disease Using Borassus flabellifer Linn
Abu-Elfotuh_2022_Biomed.Pharmacother_153_113330Evaluating the neuroprotective activities of vinpocetine, punicalagin, niacin and vitamin E against behavioural and motor disabilities of manganese-induced Parkinson's disease in Sprague Dawley rats
Abuobeid_2022_Int.J.Mol.Sci_23_Squalene through Its Post-Squalene Metabolites Is a Modulator of Hepatic Transcriptome in Rabbits
Acosta-Jimenez_2022_Molecules_27_QSTR Modeling to Find Relevant DFT Descriptors Related to the Toxicity of Carbamates
Acquaroni_2022_J.Environ.Sci.Health.B__1Acute, chronic and neurotoxic effects of dimethoate pesticide on Rhinella arenarum throughout the development
Adaixo_2022_Nat.Commun_13_61Cryo-EM structure of native human thyroglobulin
Adebayo_2022_Andrologia__e14636Nutraceutical potential of almond fruits in managing diabetes-related erectile dysfunction: Effect on Nrf-2 level and smooth muscle/collagen ratio
Adedara_2022_Ecotoxicol.Environ.Saf_239_113635Induction of aggression and anxiety-like responses by perfluorooctanoic acid is accompanied by modulation of cholinergic- and purinergic signaling-related parameters in adult zebrafish
Adedara_2022_Neurotoxicol__Kaempferol counteracts toxicity induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in D. melanogaster: An implication of its mitoprotective activity
Adedara_2022_Sci.Rep_12_3922An assessment of the rescue action of resveratrol in parkin loss of function-induced oxidative stress in Drosophila melanogaster
Adefegha_2022_Andrologia__e14629Aqueous extract of Massularia acuminata exerts erectogenic effect by modulating critical enzymes and hormones in streptozotocin-induced erectile dysfunction in rats
Ademiluyi_2022_Drug.Chem.Toxicol__1Evaluating Water bitter leaf (Struchium sparganophora) and Scent Leaf (Ocimum gratissimum) extracts as sources of nutraceuticals against manganese-induced toxicity in fruit fly model
Ademosun_2022_Curr.Res.Food.Sci_5_366Influence of Moringa (Moringa oleifera) enriched ice creams on rats' brain: Exploring the redox and cholinergic systems
Adeniyi_2022_Nutr.Neurosci__1Neuropharmacological effects of honey in lipopolysaccharide-induced neuroinflammation, cognitive impairment, anxiety and motor impairment
Adeowo_2022_Mol.Divers__Pharmacophore mapping of the crucial mediators of acetylcholinesterase and butyrylcholinesterase dual inhibition in Alzheimer's disease
Adewole_2022_Curr.Drug.Discov.Technol__Computer-aided identification of cholinergic and monoaminergic inhibitory flavonoids from Hibiscus sabdariffa L
Adithya_2022_J.Assoc.Physicians.India_70_11RDW a Predictor in OP Poisoning
Admassie_2022_Biomed.Res.Int_2022_6778352In Vitro Evaluation of Extracellular Enzyme Activity and Its Biocontrol Efficacy of Bacterial Isolates from Pepper Plants for the Management of Phytophthora capsici
Adomnien_2022_Plants.(Basel)_11_Health Beneficial Phytochemicals in Dioscorea caucasica Lipsky Leaves and Tubers and Their Inhibitory Effects on Physiologically Important Enzymes
Adorni_2022_Front.Immunol_13_935241HDL metabolism and functions impacting on cell cholesterol homeostasis are specifically altered in patients with abdominal aortic aneurysm
Aer_2022_Environ.Res_212_113472Overexpression and kinetic analysis of Ideonella sakaiensis PETase for polyethylene terephthalate (PET) degradation
Afsar_2022_BMC.Complement.Med.Ther_22_179Reversal of cisplatin triggered neurotoxicity by Acacia hydaspica ethyl acetate fraction via regulating brain acetylcholinesterase activity, DNA damage, and pro-inflammatory cytokines in the rodent model
Afzal_2022_Biomolecules_12_Anti-Huntington's Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents
Afzal_2022_Molecules_27_Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress Leaded Caspase-3/9 and TNF-alpha Signaling Pathways
Agarwal_2022_Chem.Commun.(Camb)__The yin and yang of intracellular delivery of amphipathic optical probes using n-butyl charge masking
Aggarwal_2022_Physiol.Behav__113767Neurobehavioral and neurobiochemical effect of atomoxetine and N-acetylcysteine in streptozotocin diabetes induced endothelial dysfunction and related dementia
Aggarwal_2022_Top.Curr.Chem.(Cham)_380_10Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold
Agha_2022_J.Enzyme.Inhib.Med.Chem_37_1241Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening
Aghamolaei_2022_RSC.Adv_12_5971Preparation and characterization of stable core/shell Fe(3)O(4)@Au decorated with an amine group for immobilization of lipase by covalent attachment
Aguera_2022_Environ.Toxicol.Pharmacol__103874Risk evaluation of occupational exposure of southern Brazilian flower farmers to pesticides potentially leading to cholinesterase inhibition and metals exposure
Agyekum_2022_Parasit.Vectors_15_163Relationship between temperature and Anopheles gambiae sensu lato mosquitoes' susceptibility to pyrethroids and expression of metabolic enzymes
Ahadji-Dabla_2022_Heliyon_8_e09770Resistance intensity status of Anopheles gambiae s.l. species at KOLOKOPE, eastern plateau Togo: A potential site to assess new vector control tools
Aher_2022_Front.Plant.Sci_13_962667Loss-of-function of triacylglycerol lipases are associated with low flour rancidity in pearl millet [Pennisetum glaucum (L.) R. Br.]
Ahmad_2022_CNS.Neurol.Disord.Drug.Targets_21_610Strategic Approaches to Target the Enzymes using Natural Compounds for the Management of Alzheimer's Disease: A Review
Ahmad_2022_Cell.Mol.Biol.(Noisy-le-grand)_67_106Emetine and Indirubin- 3- monoxime interaction with human brain acetylcholinesterase: A computational and statistical analysis
Ahmad_2022_Eur.J.Pharmacol__175445Anti-pancreatic lipase and anti-adipogenic effects of 5, 7, 3',4',5' -pentamethoxy and 6, 2',4'-trimethoxy flavone - An In vitro study
Ahmad_2022_Fitoterapia__105268Isolation, crystal structure, DFT calculation and molecular docking of uncinatine-A isolated from Delphinium uncinatum
Ahmad_2022_Molecules_27_In Vitro and In Silico Investigation of Diterpenoid Alkaloids Isolated from Delphinium chitralense
Ahmad_2022_Plants.(Basel)_12_Bioassay Analysis and Molecular Docking Study Revealed the Potential Medicinal Activities of Active Compounds Polygonumins B, C and D from Polygonum minus (Persicaria minor)
Ahmad_2022_World.J.Crit.Care.Med_11_228Medicinal nicotine in COVID-19 acute respiratory distress syndrome, the new corticosteroid
Ahmadi_2022_Pestic.Biochem.Physiol_184_105115Biochemical and insecticidal effects of plant essential oils on insecticide resistant and susceptible populations of Musca domestica L. point to a potential cross-resistance risk
Ahmed_2022_Int.J.Biol.Macromol__A thermotolerant and pH stable rhamnogalacturonan acetylesterase (CtPae12B), a family 12 carbohydrate esterase from Clostridium thermocellum with broad substrate specificity
Ahmed_2022_Int.J.Neurosci__1Pharmacological Evaluation of Newly Synthesized Benzimidazole Derivative for Anti-Alzheimer Potential
Ahmed_2022_Mar.Drugs_20_Evaluation of a Thermophilic, Psychrostable, and Heavy Metal-Resistant Red Sea Brine Pool Esterase
Aibara_2022_Endocr.J__Lipase family member N is a novel target gene for CCAAT/enhancer-binding protein alpha in type 2 diabetic model mouse liver
Aissous_2022_Drug.Chem.Toxicol__1The preventive effects of Centaurea maroccana Ball. extract against oxidative stress induced by cisplatin in mice brains: in vitro and in vivo studies
Ajayi_2022_J.Biochem.Mol.Toxicol__e23252Aggressive-like behaviour and neurocognitive impairment in alcohol herbal mixture-fed mice are associated with increased neuroinflammation and neuronal apoptosis in the prefrontal cortex
Ajayi_2022_Metab.Brain.Dis__Repeated social defeat stress exacerbates lipopolysaccharide-induced behavioural deficits in mice: ameliorative role of Chrysophyllum albidum fruit extract through anti-neuroinflammation, antioxidant and neurochemical balance
Ajiboye_2022_Bioinform.Biol.Insights_16_11779322221115546Effect of Flavonoid-Rich Extract From Dalbergiella welwitschii Leaf on Redox, Cholinergic, Monoaminergic, and Purinergic Dysfunction in Oxidative Testicular Injury: Ex Vivo and In Silico Studies
Akay_2022_Protein.J__Inhibitory Action of Omega-3 and Omega-6 Fatty Acids Alpha-Linolenic, Arachidonic and Linoleic acid on Human Erythrocyte Acetylcholinesterase
Akbari_2022_Neurosci.Lett_795_137041Comparative investigation of analgesic tolerance to taurine, sodium salicylate and morphine: Involvement of peripheral muscarinic receptors
Akbarian_2022_Inflammopharmacology__Amelioration of oxidative stress, cholinergic dysfunction, and neuroinflammation in scopolamine-induced amnesic rats fed with pomegranate seed
Akhter_2022_PLoS.One_17_e0273368Optimization and characterization of alkaliphilic lipase from a novel Bacillus cereus NC7401 strain isolated from diesel fuel polluted soil
Akinade_2022_Sci.Rep_12_4594Protective capacity of carotenoid trans-astaxanthin in rotenone-induced toxicity in Drosophila melanogaster
Akinpelu_2022_Polymers.(Basel)_14_A Bibliometric Analysis of Research Trends in Biodegradation of Plastics
Akinyelu_2022_Pharm.Nanotechnol__Evaluation of the antioxidant, antidiabetic, and anticholinesterase potential of biogenic silver nanoparticles from Khaya grandifoliola
Akram_2022_Mol.Biotechnol__An Appraisal on Prominent Industrial and Biotechnological Applications of Bacterial Lipases
Aksoy_2022_Turk.J.Pharm.Sci_19_76Essential Oil Content, Antioxidative Characteristics and Enzyme Inhibitory Activity of Sideritis akmanii Aytac, Ekici & Donmez
Aktas_2022_Heliyon_8_e10625The palladium-based complexes bearing 1,3-dibenzylbenzimidazolium with morpholine, triphenylphosphine, and pyridine derivate ligands: synthesis, characterization, structure and enzyme inhibitions
Akter_2022_Front.Pharmacol_13_1010103Pomegranate juice fermented by tannin acyl hydrolase and Lactobacillus vespulae DCY75 enhance estrogen receptor expression and anti-inflammatory effect
Al Khashali_2022_Int.J.Mol.Sci_23_Regulation of the Soluble Amyloid Precursor Protein alpha (sAPPalpha) Levels by Acetylcholinesterase and Brain-Derived Neurotrophic Factor in Lung Cancer Cell Media
Al Qahtani_2022_Chem.Biodivers__Chemical profile, antioxidant and enzyme inhibition activities of natural Saudi Sidr and Talh honeys
Al-Amin_2022_Adv.Pharmacol.Pharm.Sci_2022_8305271Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress
Al-Asmari_2022_Saudi.J.Biol.Sci_29_103307Arabica coffee and olive oils mitigate malathion-induced nephrotoxicity in rat: In silico, immunohistochemical and biochemical evaluation
Al-Ghamdi_2022_Environ.Sci.Pollut.Res.Int__Inhibition of dipeptidyl peptidase-4 (DPP4), antioxidant, antiglycation and anti-inflammatory effect of Ferulic acid against streptozotocin toxicity mediate nephropathy in diabetic rats
Al-Hakim_2022_Pharm.Nanotechnol__Effect of Banana (Musa sp.) Peels Extract in Nanoemulsion Dosage Forms for the Improvement of Memory: In vitro & In vivo Studies
Al-Joufi_2022_Brain.Sci_12_Flavonoid Derivatives as Potential Cholinesterase Inhibitors in Scopolamine-Induced Amnesic Mice: An In Vitro, In Vivo and Integrated Computational Approach
Al-Khayri_2022_Plants.(Basel)_11_Phenolic Profile and Antioxidant, Anticholinergic, and Antibacterial Properties of Corn Tassel
Al-Maharik_2022_Molecules_27_Isolation, Identification and Pharmacological Effects of Mandragora autumnalis Fruit Flavonoids Fraction
Al-Shabrawey_2022_Life.Res.(Auckl)_5_Hyperhomocysteinemia dysregulates plasma levels of polyunsaturated fatty acids-derived eicosanoids
Al-Shammari_2022_Genes.(Basel)_13_Identification and Characterization of Variants in Intron 6 of the LPL Gene Locus among a Sample of the Kuwaiti Population
Al-Waili_2022_Front.Genet_13_886182The Genetic Spectrum of Familial Hypertriglyceridemia in Oman
Al_2022_Histochem.Cell.Biol__Immunohistochemistry for acetylcholinesterase and butyrylcholinesterase in the dorsal motor nucleus of the vagus (DMNV) of formalin-fixed, paraffin-embedded tissue: comparison with reported literature
Aladodo_2022_Evid.Based.Complement.Alternat.Med_2022_4388941Toxicological Evaluation and In Silico Identification of Acetylcholinesterase Inhibitors in a Commercial Polyherbal Formulation (KWAPF01)
Alam_2022_Mol.Plant.Pathol__Opposing effects of MYZUS PERSICAE-INDUCED LIPASE 1 and jasmonic acid influence the outcome of Arabidopsis thaliana-Fusarium graminearum interaction
Alanazi_2022_Plants.(Basel)_11_Acaricidal, Larvacidal, and Repellent Activity of Elettaria cardamomum Essential Oil against Hyalomma anatolicum Ticks Infesting Saudi Arabian Cattle
Alarcon-Enos_2022_J.Enzyme.Inhib.Med.Chem_37_1845Dyhidro-beta-agarofurans natural and synthetic as acetylcholinesterase and COX inhibitors: interaction with the peripheral anionic site (AChE-PAS), and anti-inflammatory potentials
Alasmari_2022_CNS.Neurol.Disord.Drug.Targets__Therapeutic effects of thymoquinone on Alzheimer's disease through modulating amyloid beta neurotoxicity and neuro-inflammatory cytokine levels
Alavi_2022_Metab.Brain.Dis__Beneficial effects of levetiracetam in streptozotocin-induced rat model of Alzheimer's disease
Albayrak_2022_Chem.Biodivers__Anticholinesterase compounds from endemic Prangos uechtritzii
Albayrak_2022_Pestic.Biochem.Physiol_180_104984Pirimicarb resistance and associated mechanisms in field-collected and selected populations of Neoseiulus californicus
Albert_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2113488119Genome-wide association identifies a missing hydrolase for tocopherol synthesis in plants
Albrakati_2022_Environ.Sci.Pollut.Res.Int__Monosodium glutamate induces cortical oxidative, apoptotic, and inflammatory challenges in rats: the potential neuroprotective role of apigenin
Alcantara-Quintana_2022_Cancer.Manag.Res_14_2225Effect of Exosomes from Patients with Grade One Cervical Intraepithelial Neoplasia on Cell Cultures: A Preliminary Study
Alejaldre_2022_Biochemistry__Tuning Selectivity in CalA Lipase: Beyond Tunnel Engineering
Alharbi_2022_Medicina.(Kaunas)_58_Rosinidin Protects Streptozotocin-Induced Memory Impairment-Activated Neurotoxicity by Suppressing Oxidative Stress and Inflammatory Mediators in Rats
Alhazmi_2022_Saudi.Pharm.J_30_1755An update on the novel and approved drugs for Alzheimer disease
Ali_2022_Antonie.Van.Leeuwenhoek__Serratia sp. scl1: isolation of a novel thermostable lipase producing microorganism which holds industrial importance
Ali_2022_Bioorg.Chem_127_105944Isolation, derivatization, in-vitro, and in-silico studies of potent butyrylcholinesterase inhibitors from Berberis parkeriana Schneid
Ali_2022_PLoS.One_17_e0271138Effects of antidiabetic agents on Alzheimer's disease biomarkers in experimentally induced hyperglycemic rat model by streptozocin
Aliakbarzadeh_2022_Environ.Pollut__120587Adverse effects of polystyrene nanoplastic and its binary mixtures with nonylphenol on zebrafish nervous system: From oxidative stress to impaired neurotransmitter system
Alimi_2022_Vet.Parasitol_303_109665Phytochemistry, anti-tick, repellency and anti-cholinesterase activities of Cupressus sempervirens L. and Mentha pulegium L. combinations against Hyalomma scupense (Acari: Ixodidae)
Alimi_2022_Vet.Parasitol_309_109743Acaricidal and anthelmintic efficacy of Ocimum basilicum essential oil and its major constituents estragole and linalool, with insights on acetylcholinesterase inhibition
Alipanah_2022_Environ.Toxicol__Subacute toxicity of chlorpyrifos on histopathological damages, antioxidant activity, and pro-inflammatory cytokines in the rat model
Aliwarga_2022_Int.J.Mol.Sci_23_Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and Degradation
Aljubiri_2022_Z.Naturforsch.C.J.Biosci__In vitro acetylcholinesterase, tyrosinase inhibitory potentials of secondary metabolites from Euphorbia schimperiana and Euphorbia balsamifera
Alkharsah_2022_PLoS.One_17_e0266603Low levels of soluble DPP4 among Saudis may have constituted a risk factor for MERS endemicity
Allard_2022_Chem.Biol.Interact__109996Design and production strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning
Allen_2022_Cochrane.Database.Syst.Rev_6_CD011574Interventions for preventing falls in Parkinson's disease
Alma'abadi_2022_N.Biotechnol__Identification of Lipolytic Enzymes Using High-Throughput Single-cell Screening and Sorting of a Metagenomic Library
Almadiy_2022_Environ.Sci.Pollut.Res.Int__Bioactivity of Deverra tortuosa essential oil, its nanoemulsion, and phenylpropanoids against the cowpea weevil, a stored grain pest with eco-toxicological evaluations
Almaliti_2022_Molecules_27_Discovery of Novel Epoxyketone Peptides as Lipase Inhibitors
Almaz_2022_J.Biochem.Mol.Toxicol__e23277Investigation of biological activities of various 1,2,3-triazole compounds: Their effects on cholinesterase enzymes, determination of antioxidant capacity and antimicrobial activity
Almutairi_2022_Life.(Basel)_12_Phytochemical Analysis and Binding Interaction of Cotton Seed Cake Derived Compounds with Target Protein of Meloidogyne incognita for Nematicidal Evaluation
Alonazi_2022_Molecules_27_Biochemical, Kinetic and Biological Properties of Group V Phospholipase A2 from Dromedary
Alov_2022_Int.J.Mol.Sci_23_In Silico Identification of Multi-Target Ligands as Promising Hit Compounds for Neurodegenerative Diseases Drug Development
Alqahtani_2022_Molecules_27_Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation
Alshehri_2022_Evid.Based.Complement.Alternat.Med_2022_6726438Succinimide Derivatives as Antioxidant Anticholinesterases, Anti-alpha-Amylase, and Anti-alpha-Glucosidase: In Vitro and In Silico Approaches
Alshehri_2022_Neurotox.Res__Anti-Huntington's Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action
Altammar_2022_Int.J.Biol.Macromol__Characterization of AnCUT3, a plastic-degrading paucimannose cutinase from Aspergillus niger expressed in Pichia pastoris
Altay_2022_Chem.Biodivers__e202200348A Biochemical Approach for Hedysarum candidissimum from Turkey: Screening Phytochemicals, Evaluation of Biological Activites, and Molecular Docking Study
Althaher_2022_ScientificWorldJournal_2022_1964684An Overview of Hormone-Sensitive Lipase (HSL)
Althobaiti_2022_Antioxidants.(Basel)_11_Ethnomedicinal Plants with Protective Effects against Beta-Amyloid Peptide (Abeta)1-42 Indicate Therapeutic Potential in a New In Vivo Model of Alzheimer's Disease
Altilia_2022_Clin.Chem.Lab.Med__Biological variation of serum cholinesterase catalytic concentrations
Alvarez-Berbel_2022_Pharmaceutics_14_Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid- Aggregation and Acetylcholinesterase-Amyloid Interaction
Alvarez-Ortiz_2022_Biorxiv__Down-regulation of Drosophila Glutactin, a cholinesterase-like adhesion molecule of the basement membrane, impairs development, compromises adult function and shortens lifespan
Alvarez-Vergara_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_258_109367Biochemical and osmoregulatory responses of the African clawed frog experimentally exposed to salt and pesticide
Alves_2022_Mar.Pollut.Bull_176_113418Elasmobranchs as bioindicators of pollution in the marine environment
Alvez_2022_Cell.Mol.Neurobiol__Effect of Thiazolidin-4-one Against Lipopolysaccharide-Induced Oxidative Damage, and Alterations in Adenine Nucleotide Hydrolysis and Acetylcholinesterase Activity in Cultured Astrocytes
Aly_2022_Molecules_27_Chemical Constituents, Antioxidant, and Enzyme Inhibitory Activities Supported by In-Silico Study of n-Hexane Extract and Essential Oil of Guava Leaves
Alzarea_2022_Front.Pharmacol_13_810052Butin Attenuates Arthritis in Complete Freund's Adjuvant-Treated Arthritic Rats: Possibly Mediated by Its Antioxidant and Anti-Inflammatory Actions
Amaral_2022_Ecotoxicol.Environ.Saf_242_113831Fitness cost and reversion of resistance Leucoptera coffeella (Lepidoptera: Lyonetiidae) to chlorpyrifos
Amat_2022_Brain.Behav.Evol__Neurogenetic heterochrony in chick, lizard and rat mapped with wholemount AChE and the prosomeric model
Amenyogbe_2022_Sci.Rep_12_17410Effects of autochthonous strains mixture on gut microbiota and metabolic profile in cobia (Rachycentron canadum)
Amer_2022_Insects_13_Copper Exposure Affects Anti-Predatory Behaviour and Acetylcholinesterase Levels in Culex pipiens (Diptera, Culicidae)
Amir_2022_Molecules_27_In Vitro and In Silico Anti-Acetylcholinesterase Activity from Macaranga tanarius and Syzygium jambos
Amir_2022_PLoS.One_17_e0264207Isolation and optimization of extracellular PHB depolymerase producer Aeromonas caviae Kuk1-(34) for sustainable solid waste management of biodegradable polymers
Amir_2022_Plants.(Basel)_11_Roles of Syzygium in Anti-Cholinesterase, Anti-Diabetic, Anti-Inflammatory, and Antioxidant: From Alzheimer's Perspective
Amirahmadi_2022_Inflammopharmacology__Minocycline attenuates cholinergic dysfunction and neuro-inflammation-mediated cognitive impairment in scopolamine-induced Alzheimer's rat model
Amprosi_2022_Front.Neurol_12_799953Mast Syndrome Outside the Amish Community: SPG21 in Europe
An_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_261_109440Thiobencarb induces phenotypic abnormalities, apoptosis, and cardiovascular toxicity in zebrafish embryos through oxidative stress and inflammation
Anajirih_2022_Prostaglandins.Other.Lipid.Mediat__106692Endocannabinoid hydrolases differentially distribute in platelets and red blood cells and are differentially released by thrombin
Anand_2022_Front.Neurosci_16_1005972Ameliorative effect of vanillin on scopolamine-induced dementia-like cognitive impairment in a mouse model
Anderson_2022_J.Clin.Psychiatry_84_The Differential Diagnosis and Treatment of Mild Cognitive Impairment and Alzheimer Disease
Andrade_2022_J.Clin.Psychiatry_83_Reconsideration of the Benefits of Pharmacological Interventions for the Attenuation of the Cognitive Adverse Effects of Electroconvulsive Therapy
Andrade_2022_PLoS.One_17_e0268292Suillin: A mixed-type acetylcholinesterase inhibitor from Suillus luteus which is used by Saraguros indigenous, southern Ecuador
Andre_2022_J.Sep.Sci__Development of nano Bio LC columns for the search of acethylcholinesterase molecular targets
Andrzejewski_2022_Int.J.Mol.Sci_23_Hypoxic and Hypercapnic Responses in Transgenic Murine Model of Alzheimer's Disease Overexpressing Human AbetaPP: The Effects of Pretreatment with Memantine and Rivastigmine
Angelia_2022_Prostaglandins.Other.Lipid.Mediat__106702Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior
Angelopoulou_2022_Molecules_27_Emerging Potential of the Phosphodiesterase (PDE) Inhibitor Ibudilast for Neurodegenerative Diseases: An Update on Preclinical and Clinical Evidence
Angulo_2022_Biomedica_42_445Neuroleptic malignant syndrome associated with acute organophosphate poisoning: Case report
Anil_2022_Comput.Biol.Chem_100_107748Exploring enzyme inhibition profiles of novel halogenated chalcone derivatives on some metabolic enzymes: Synthesis, characterization and molecular modeling studies
Anita_2022_Int.J.Mol.Sci_23_Soluble Epoxide Hydrolase and Diabetes Complications
Anoush_2022_ACS.Omega_7_13861Clavulanic Acid: A Novel Potential Agent in Prevention and Treatment of Scopolamine-Induced Alzheimer's Disease
Anstey_2022_Mol.Autism_13_34Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3(-/y) rat model of autism
Antika_2022_ACS.Chem.Neurosci_13_572Strigolactone Analogs: Two New Potential Bioactiphores for Glioblastoma
Antonova_2022_Wiad.Lek_75_2779Epoxid hydrolase single gene polymorphism (RS1051740) and severity of chronic obstructive disease
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Borovsky_2022_Biomolecules_12_991Cloning and Characterization of Drosophila melanogaster Juvenile Hormone Epoxide Hydrolases (JHEH) and Their Promoters
Borowiec_2022_Food.Chem_391_133281Polyphenols composition and the biological effects of six selected small dark fruits
Borowiecki_2022_Int.J.Mol.Sci_23_Chemoenzymatic Synthesis of Optically Active Ethereal Analog of iso-Moramide-A Novel Potentially Powerful Analgesic
Bortolami_2022_Pharmaceuticals.(Basel)_15_Design, Synthesis, and In Vitro, In Silico and In Cellulo Evaluation of New Pyrimidine and Pyridine Amide and Carbamate Derivatives as Multi-Functional Cholinesterase Inhibitors
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Bottermann_2022_Basic.Res.Cardiol_117_48Cardiomyocyte p38 MAPKalpha suppresses a heart-adipose tissue-neutrophil crosstalk in heart failure development
Boukadida_2022_Mar.Environ.Res_179_105677Metal contamination and heat stress impair swimming behavior and acetylcholinesterase activity in embryo-larval stages of the Mediterranean mussel, Mytilus galloprovincialis
Bouslamti_2022_Molecules_27_Solanum elaeagnifolium Var. Obtusifolium (Dunal) Dunal: Antioxidant, Antibacterial, and Antifungal Activities of Polyphenol-Rich Extracts Chemically Characterized by Use of In Vitro and In Silico Approaches
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Braeckmans_2022_Int.J.Pharm__121807Orlistat disposition in the human jejunum and the effect of lipolysis inhibition on bile salt concentrations and composition
Brandenberg_2022_Microb.Cell.Fact_21_119Towards synthetic PETtrophy: Engineering Pseudomonas putida for concurrent polyethylene terephthalate (PET) monomer metabolism and PET hydrolase expression
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Bricola_2022_Cell.Biochem.Funct__Aging reduces ABHD5 protein content in the adipose tissue of mice: The reversal effect of exercise
Brinkley_2022_Front.Neurosci_16_906539Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer's Disease
Brinza_2022_Molecules_27_Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (Danio rerio) Model: Involvement of Cholinergic System and Brain Oxidative Stress
Britikov_2022_Crystals_12_712Elucidation of the Conformational Transition of Oligopeptidase B by an Integrative Approach Based on the Combination of X-ray, SAXS, and Essential Dynamics Sampling Simulation
Britton_2022_BMC.Res.Notes_15_183Contribution of a novel gene to lysergic acid amide synthesis in Metarhizium brunneum
Brooks_2022_Biochem.Biophys.Res.Commun_630_572.1 A crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1)
Brott_2022_Eng.Life.Sci_22_192Engineering and evaluation of thermostable IsPETase variants for PET degradation
Brown_2022_Methods.Mol.Biol_2547_427The Pharmacogenetic Impact on the Pharmacokinetics of ADHD Medications
Brown_2022_Pathogens_11_1245Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity
Brunetti_2022_Eur.J.Med.Chem_237_114358Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease
Brunst_2022_ACS.Med.Chem.Lett_13_1062Designing a Small Fluorescent Inhibitor to Investigate Soluble Epoxide Hydrolase Engagement in Living Cells
Bu_2022_J.Alzheimers.Dis__Dysphagia Risk in Patients Prescribed Rivastigmine: A Systematic Analysis of FDA Adverse Event Reporting System
Buchholz_2022_Proteins_90_1443Plastics degradation by hydrolytic enzymes: The plastics-active enzymes database-PAZy
Budryn_2022_Nutrients_14_Hydroxybenzoic Acids as Acetylcholinesterase Inhibitors: Calorimetric and Docking Simulation Studies
Bugay_2022_Front.Neurosci_16_866899Effects of Sublethal Organophosphate Toxicity and Anti-cholinergics on Electroencephalogram and Respiratory Mechanics in Mice
Burgart_2022_Molecules_28_Powerful Potential of Polyfluoroalkyl-Containing 4-Arylhydrazinylidenepyrazol-3-ones for Pharmaceuticals
Burger_2022_Plant.Direct_6_e466Crystal structure of Arabidopsis DWARF14-LIKE2 (DLK2) reveals a distinct substrate binding pocket architecture
Burgess_2022_PLoS.One_17_e0268205Assessing pyrethroid resistance status in the Culex pipiens complex (Diptera: Culicidae) from the northwest suburbs of Chicago, Illinois using Cox regression of bottle bioassays and other detection tools
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Burton_2022_J.Pediatr.Gastroenterol.Nutr__Long-term Sebelipase Alfa Treatment in Children and Adults With Lysosomal Acid Lipase Deficiency
Burzynski_2022_Neurobiol.Stress_18_100446Pyridostigmine bromide elicits progressive and chronic impairments in the cholinergic anti-inflammatory pathway in the prefrontal cortex and hippocampus of male rats
Bykov_2022_Sex.Med_10_100477Ipidacrine (Axamon), A Reversible Cholinesterase Inhibitor, Improves Erectile Function in Male Rats With Diabetes Mellitus-Induced Erectile Dysfunction
Byun_2022_Sci.Rep_12_4451Analysis of treatment pattern of anti-dementia medications in newly diagnosed Alzheimer's dementia using OMOP CDM
Bzowka_2022_PLoS.Comput.Biol_18_e1010119Evolution of tunnels in alpha/beta-hydrolase fold proteins-What can we learn from studying epoxide hydrolases?
Cacabelos_2022_Methods.Mol.Biol_2547_275Pharmacogenomics of Alzheimer's Disease: Novel Strategies for Drug Utilization and Development
Cachatra_2022_Med.Chem__Revisiting Purine Nucleoside Cholinesterase Inhibitors - An Experimental Glycon Structure/Activity Relationship Study
Cai_2022_Enzyme.Microb.Technol_155_109992Nanobodies as binding-chaperones stabilize the recombinant Bombyx mori acetylcholinesterase and protect the enzyme activity in pesticide detection
Cai_2022_J.Econ.Entomol__Sublethal Effects of Thiamethoxam on Biological Traits and Detoxification Enzyme Activities in the Small Brown Planthopper, Laodelphax striatellus (Falln)
Cakmak_2022_Arch.Pharm.(Weinheim)__e2100430Synthesis, characterization, and biological evaluation of some novel Schiff bases as potential metabolic enzyme inhibitors
Calderaro_2022_Int.J.Mol.Sci_23_The Neuroprotective Potentiality of Flavonoids on Alzheimer's Disease
Calva_2022_Pharm.Biol_60_206Chemical composition, enantiomeric analysis and anticholinesterase activity of Lepechinia betonicifolia essential oil from Ecuador
Campagna_2022_Int.J.Mol.Sci_24_Role Played by Paraoxonase-2 Enzyme in Cell Viability, Proliferation and Sensitivity to Chemotherapy of Oral Squamous Cell Carcinoma Cell Lines
Camporesi_2022_EBioMedicine_75_103793Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry
Campos_2022_Phytochem.Anal__Alternative method for microenzymatic inhibition activities monitoring from Baccharis trimera extracts by CZE-UV
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Cannazza_2022_Biotechnol.Adv__107985Mycobacterium smegmatis acyltransferase: The big new player in biocatalysis
Cano-Rocabayera_2022_Aquat.Toxicol_248_106193An integrated biomarker approach: Non-monotonic responses to cadmium exposure in the suckermouth catfish Hypostomus plecostomus
Cao_2022_Cell.Rep_41_111771NMDA receptor hypofunction underlies deficits in parvalbumin interneurons and social behavior in neuroligin 3 R451C knockin mice
Cao_2022_Chemosphere__134691Toxic effects of glyphosate on the intestine, liver, brain of carp and on epithelioma papulosum cyprinid cells: Evidence from in vivo and in vitro research
Cao_2022_Food.Chem_381_132282An efficient multi-enzyme cascade platform based on mesoporous metal-organic frameworks for the detection of organophosphorus and glucose
Cao_2022_Front.Bioeng.Biotechnol_10_1051233Construction of microbial consortia for microbial degradation of complex compounds
Cao_2022_Front.Endocrinol.(Lausanne)_13_992875PRDX6: A protein bridging S-palmitoylation and diabetic neuropathy
Cao_2022_Front.Neurol_13_1034243Promising candidates from drug clinical trials: Implications for clinical treatment of Alzheimer's disease in China
Cao_2022_Toxicol.Lett_361_1Neuroligin-1 plays an important role in methamphetamine-induced hippocampal synaptic plasticity
Capan_2022_ChemMedChem__Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitors
Capece_2022_Mol.Cell.Oncol_9_2024051Rewired lipid metabolism as an actionable vulnerability of aggressive colorectal carcinoma
Capitao_2022_Nanomaterials.(Basel)_12_Single and Mixture Toxicity of Boron and Vanadium Nanoparticles in the Soil Annelid Enchytraeus crypticus: A Multi-Biomarker Approach
Capo_2022_Environ.Res_211_113063Quantification of differential tissue biomarker responses to microplastic ingestion and plasticizer bioaccumulation in aquaculture reared sea bream Sparus aurata
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Caratelli_2022_Biosens.Bioelectron_205_114119A paper-based electrochemical device for the detection of pesticides in aerosol phase inspired by nature: A flower-like origami biosensor for precision agriculture
Carbone_2022_Neurogastroenterol.Motil__e14337A double-blind randomized, multicenter, placebo-controlled study of itopride in functional dyspepsia postprandial distress syndrome
Cardona-Ruda_2022_Toxins.(Basel)_14_Anti-Neurotoxins from Micrurus mipartitus in the Development of Coral Snake Antivenoms
Cardoso-Vera_2022_Sci.Total.Environ__155359Multi-biomarker approach to evaluate the neurotoxic effects of environmentally relevant concentrations of phenytoin on adult zebrafish Danio rerio
Cardozo-Munoz_2022_Molecules_27_Multitarget Action of Xanthones from Garcinia mangostana against alpha-Amylase, alpha-Glucosidase and Pancreatic Lipase
Carocci_2022_Antioxidants.(Basel)_11_Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease
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Carr_2022_Front.Microbiol_13_888343Identification of BgP, a Cutinase-Like Polyesterase From a Deep-Sea Sponge-Derived Actinobacterium
Cartuche_2022_Plants.(Basel)_11_Chemical and Biological Activity Profiling of Hedyosmum strigosum Todzia Essential Oil, an Aromatic Native Shrub from Southern Ecuador
Carvalho_2022_Angew.Chem.Int.Ed.Engl__Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9
Cascaes_2022_Antioxidants.(Basel)_11_Phytochemical Profile, Antioxidant Potential and Toxicity Evaluation of the Essential Oils from Duguetia and Xylopia Species (Annonaceae) from the Brazilian Amazon
Casedas_2022_Front.Pharmacol_13_1009868Evaluation of two different Cannabis sativa L. extracts as antioxidant and neuroprotective agents
Cavallero_2022_Life.Sci__121147Presence, enzymatic activity, and subcellular localization of paraoxonases 1, 2, and 3 in human lung tissues
Cea-Rama_2022_FEBS.J__Crystal structure of a family VIII beta-lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope
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Cenci_2022_Int.J.Mol.Sci_23_Genome-Wide Classification and Phylogenetic Analyses of the GDSL-Type Esterase/Lipase (GELP) Family in Flowering Plants
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Chahouri_2022_Chemosphere__134149Integration assay of bacteriological risks in marine environment using salmonella spp and multimarker response in the bivalve Donax trunculus: Novel biomonitoring approach
Chai_2022_Front.Endocrinol.(Lausanne)_13_994944Effect of dipeptidyl peptidase-4 inhibitors on postprandial glucagon level in patients with type 2 diabetes mellitus: A systemic review and meta-analysis
Chaichompoo_2022_Phytochemistry_205_113473Alkaloids with cholinesterase inhibitory activities from the bulbs of Crinum amabile Donn ex Ker Gawl
Chaiyana_2022_Molecules_27_Enhancement of Cholinesterase Inhibition of Alpinia galanga (L.) Willd. Essential Oil by Microemulsions
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Chandra_2022_J.Assoc.Physicians.India_70_11Serum Amylase and Lipase Estimation in Diabetic Ketoacidosis
Chang_2022_J.Formos.Med.Assoc__Sugammadex reversal of muscle relaxant blockade provided less Post-Anesthesia Care Unit adverse effects than neostigmine/glycopyrrolate
Chang_2022_STAR.Protoc_3_101857Non-invasive chimeric HaloTag labeling to study clustering and diffusion of membrane proteins
Changlek_2022_Foods_11_Curcumin Suppresses Lead-Induced Inflammation and Memory Loss in Mouse Model and In Silico Molecular Docking
Charles_2022_Cells_11_Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease
Charlier_2022_Biophys.J__An NMR look at an engineered PET depolymerase
Charupanit_2022_Molecules_27_In Silico Identification of Potential Sites for a Plastic-Degrading Enzyme by a Reverse Screening through the Protein Sequence Space and Molecular Dynamics Simulations
Chavez-Guevara_2022_Eur.J.Appl.Physiol__Biomarkers and genetic polymorphisms associated with maximal fat oxidation during physical exercise: implications for metabolic health and sports performance
Chea_2022_Molecules_27_Microwave-Assisted Synthesis of 5'-O-methacryloylcytidine Using the Immobilized Lipase Novozym 435
Checler_2022_Neural.Regen.Res_17_2215Aminopeptidase A and dipeptidyl peptidase 4: a pathogenic duo in Alzheimer's disease?
Chelikani_2022_Cureus_14_e28215A Rare Case of Hashimoto's Encephalopathy With Mosaic Turner Syndrome
Chellammal_2022_J.Diabetes.Metab.Disord_21_1415Metformin inhibits cardiometabolic syndrome associated cognitive deficits in high fat diet rats
Chen_2022_Anal.Chim.Acta_1232_340495Highly selective SERS detection of acetylcholinesterase in human blood based on catalytic reaction
Chen_2022_Ann.Transl.Med_10_303Design, synthesis, and evaluation of 8-aminoquinoline-melatonin derivatives as effective multifunctional agents for Alzheimer's disease
Chen_2022_Antioxidants.(Basel)_11_Reduced Fitness and Elevated Oxidative Stress in the Marine Copepod Tigriopus japonicus Exposed to the Toxic Dinoflagellate Karenia mikimotoi
Chen_2022_Biomedicines_10_Vitisin A, a Resveratrol Tetramer, Improves Scopolamine-Induced Impaired Learning and Memory Functions in Amnesiac ICR Mice
Chen_2022_Biosensors.(Basel)_12_Nanoporous ZIF-8 Microparticles as Acetylcholinesterase and Alkaline Phosphatase Mimics for the Selective and Sensitive Detection of Ascorbic Acid Oxidase and Copper Ions
Chen_2022_Compr.Rev.Food.Sci.Food.Saf__Rebuilding the lid region from conformational and dynamic features to engineering applications of lipase in foods: Current status and future prospects
Chen_2022_Contrast.Media.Mol.Imaging_2022_7832564Predictive Value of Perioperative Cytokine Levels on the Risk for In-Stent Restenosis in Acute Myocardial Infarction Patients
Chen_2022_Drug.Des.Devel.Ther_16_509alpha-Mangostin Treats Early-Stage Adjuvant-Induced Arthritis of Rat by Regulating the CAP-SIRT1 Pathway in Macrophages
Chen_2022_Ecotoxicol.Environ.Saf_243_1140072, 5-dichloro-1, 4-benuinone exposure to zebrafish embryos/larvae causes neurodevelopmental toxicity
Chen_2022_Environ.Sci.Technol__Defining the Chemical Additives Driving In Vitro Toxicities of Plastics
Chen_2022_Food.Funct__Carnosic acid ameliorated Abeta-mediated (amyloid-beta peptide) toxicity, cholinergic dysfunction and mitochondrial defect in Caenorhabditis elegans of Alzheimer's Model
Chen_2022_Food.Res.Int_161_111799Intact aleurone cells limit the hydrolysis of endogenous lipids in wheat bran during storage
Chen_2022_Infect.Drug.Resist_15_1317A Novel Nomogram for Predicting Risk Factors and Outcomes in Bloodstream Infections Caused by Klebsiella pneumoniae
Chen_2022_J.Chem.Inf.Model__Activation Mechanism of Strigolactone Receptors and Its Impact on Ligand Selectivity between Host and Parasitic Plants
Chen_2022_J.Food.Sci__Ferulic acid- and gallic ester-acylated pectin: Preparation and characterization
Chen_2022_J.Hazard.Mater_433_128816Directional-path modification strategy enhances PET hydrolase catalysis of plastic degradation
Chen_2022_J.Mater.Chem.B__Construction of a copper nanocluster/MnO(2) nanosheet-based fluorescent platform for butyrylcholinesterase activity detection and anti-Alzheimer's drug screening
Chen_2022_J.Nanobiotechnology_20_347N-acylhomoserine lactonase-based hybrid nanoflowers: a novel and practical strategy to control plant bacterial diseases
Chen_2022_J.Obstet.Gynaecol__1Screening models combining maternal characteristics and multiple markers for the early prediction of preeclampsia in pregnancy: a nested case-control study
Chen_2022_J.Oleo.Sci_71_277Anti-human Glioma Cancer Potentials of Neobavaisoflavone as Natural Antioxidant Compound and Its Inhibition Profiles for Acetylcholinesterase and Butyrylcholinesterase Enzymes with Molecular Modeling and Spin Density Distributions Studies
Chen_2022_J.Pharm.Biomed.Anal_211_114632Preparation and characterization of immobilized 5-HT(1A) receptor stationary phase for high throughput screening of the receptor-binding ligands from complex systems like Curcuma wenyujin Y. H. Chen et C. Ling extract
Chen_2022_J.Zhejiang.Univ.Sci.B_23_230A new benzaldehyde from the coral-derived fungus Aspergillus terreus C23-3 and its anti-inflammatory effects via suppression of MAPK signaling pathway in RAW264.7 cells
Chen_2022_Metab.Brain.Dis__Learning and memory impairment induced by 1,4-butanediol is regulated by ERK1/2-CREB-BDNF signaling pathways in PC12 cells
Chen_2022_Mol.Metab__101600Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma
Chen_2022_Molecules_27_A Sensitive and Selective Colorimetric Method Based on the Acetylcholinesterase-like Activity of Zeolitic Imidazolate Framework-8 and Its Applications
Chen_2022_Nat.Commun_13_7138Biodegradation of highly crystallized poly(ethylene terephthalate) through cell surface codisplay of bacterial PETase and hydrophobin
Chen_2022_PLoS.Med_19_e1004124Association between antidementia medication use and mortality in people diagnosed with dementia with Lewy bodies in the UK: A retrospective cohort study
Chen_2022_Phytochemistry_196_113089Iboga-type alkaloids with Indolizidino[8,7-b]Indole scaffold and bisindole alkaloids from Tabernaemontana bufalina Lour
Chen_2022_Plant.J__New insights into the function of plant tannase with promiscuous acyltransferase activity
Cheng_2022_Acta.Pharmacol.Sin__A novel monoacylglycerol lipase-targeted (18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network
Cheng_2022_J.Agric.Food.Chem__Assessing Dietary Pesticide Intake and Potential Health Effects: The Application of Global Metabolomics Analysis
Cheng_2022_Molecules_27_Phenolic Constituents, Antioxidant and Cytoprotective Activities, Enzyme Inhibition Abilities of Five Fractions from Vaccinium dunalianum Wight
Chetoni_2022_Int.J.Pharm__122078MAGL inhibitor NanoMicellar formulation (MAGL-NanoMicellar) for the development of an antiglaucoma eye drop
Chhunchha_2022_Cells_11_Switching of Redox Signaling by Prdx6 Expression Decides Cellular Fate by Hormetic Phenomena Involving Nrf2 and Reactive Oxygen Species
Chien_2022_Langmuir__Localized Surface Plasmon Resonance-Based Colorimetric Assay Featuring Thiol-Capped Au Nanoparticles Combined with a Mobile Application for On-Site Parathion Organophosphate Pesticide Detection
Chin_2022_Cureus_14_e31065Conventional Versus New Treatment: Comparing the Effects of Acetylcholinesterase Inhibitors and N-Methyl-D-Aspartate Receptor Antagonist With Aducanumab
Cho_2022_Biochemistry_61_183Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N-Methyltransferases in Bacteria
Cho_2022_J.Vet.Sci_23_e79Correlating two-dimensional shear wave elastography of acute pancreatitis with Spec cPL in dogs
Choi_2022_Cell.Mol.Life.Sci_79_294Prenatal glucocorticoid exposure selectively impairs neuroligin 1-dependent neurogenesis by suppressing astrocytic FGF2-neuronal FGFR1 axis
Choi_2022_Foods_11_Optimization of Fermentation Conditions of Artemisia capillaris for Enhanced Acetylcholinesterase and Butyrylcholinesterase
Choi_2022_Mol.Brain_15_63Donepezil ameliorates Abeta pathology but not tau pathology in 5xFAD mice
Choi_2022_Plants.(Basel)_11_Biogenesis and Lipase-Mediated Mobilization of Lipid Droplets in Plants
Chou_2022_Nutrients_14_Benefits of Valsartan and Amlodipine in Lipolysis through PU.1 Inhibition in Fructose-Induced Adiposity
Chow_2022_Int.J.Mol.Sci_23_Rational Design of Lipase ROL to Increase Its Thermostability for Production of Structured Tags
Chrienova_2022_J.Enzyme.Inhib.Med.Chem_37_2605Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
Chu_2022_Antioxidants.(Basel)_11_Comparison of Various Solvent Extracts and Major Bioactive Components from Unsalt-Fried and Salt-Fried Rhizomes of Anemarrhena asphodeloides for Antioxidant, Anti-alpha-Glucosidase, and Anti-Acetylcholinesterase Activities
Chu_2022_Nutrients_14_Higher Serum DHA and Slower Cognitive Decline in Patients with Alzheimer's Disease: Two-Year Follow-Up
Cinar_2022_Noro.Psikiyatr.Ars_59_281Donepezil-loaded PLGA-b-PEG Nanoparticles Enhance the Learning and Memory Function of Beta-Amyloid Rat Model of Alzheimer's Disease
Cinque_2022_Nutrients_14_Interaction between Lifestyle Changes and PNPLA3 Genotype in NAFLD Patients during the COVID-19 Lockdown
Cobilinschi_2022_Toxics_10_Toxic-Induced Nonthyroidal Illness Syndrome Induced by Acute Low-Dose Pesticides Exposure-Preliminary In Vivo Study
Codony_2022_J.Med.Chem__Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors
Colvin_2022_Vet.Parasitol.Reg.Stud.Reports_27_100662Prevalence of sheep lice and trends in control practices across Australia - Australian sheep parasite control surveys from 2003 to 2019
Contador-Kelsall_2022_Conserv.Physiol_10_coac024Sublethal pesticide exposure influences behaviour, but not condition in a widespread Australian lizard
Contreras-Aguilar_2022_BMC.Vet.Res_18_275Changes in salivary analytes in cows due to the in vitro presence of feed
Cormier_2022_Environ.Pollut_308_119721Environmental microplastics disrupt swimming activity in acute exposure in Danio rerio larvae and reduce growth and reproduction success in chronic exposure in D. rerio and Oryzias melastigma
Correira_2022_Langmuir_38_3501Formation and Characterization of a Stable Monolayer of Active Acetylcholinesterase on Planar Gold
Cortes_2022_Metabolites_12_Phenolic Profile, Antioxidant and Enzyme Inhibition Properties of the Chilean Endemic Plant Ovidia pillopillo (Gay) Meissner (Thymelaeaceae)
Corvillo_2022_Diabetes__Characterization and Clinical Association of Autoantibodies Against Perilipin 1 in Patients with Acquired Generalized Lipodystrophy
Cossette_2022_Can.Liver.J_5_428Early diagnosis and successful long-term management of a rare, severe lysosomal acid lipase deficiency/Wolman disease patient: Infancy to age five
Costa_2022_Enzyme.Microb.Technol_163_110167Synthesis of organic-inorganic hybrid nanoflowers of lipases from Candida antarctica type B (CALB) and Thermomyces lanuginosus (TLL): Improvement of thermal stability and reusability
Costa_2022_Food.Res.Int_161_111851Enzymatic synthesis of ascorbyl oleate and evaluation of biological activities
Costantino_2022_Arch.Pharm.(Weinheim)__e2200142Toward the cholinesterase inhibition potential of TADDOL derivatives: Seminal biological and computational studies
Couturier_2022_Fly.(Austin)_16_360HaloTag-based reporters for sparse labeling and cell tracking
Cowen_2022_Int.J.Pharm_629_122406Nanoparticle-induced enhancement of cholinesterase activity in the presence of malathion: A potential nerve agent therapeutic
Cristancho_2022_RSC.Med.Chem_13_568Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation
Cuccaro_2022_Mar.Pollut.Bull_178_113601Biochemical response of Ficopomatus enigmaticus adults after exposure to organic and inorganic UV filters
Cuciniello_2022_Free.Radic.Biol.Med__Conjugated linoleic acid downregulates Alzheimer's hallmarks in aluminum mouse model through an Nrf2-mediated adaptive response and increases brain glucose transporter levels
Cueni_2022_J.Vet.Intern.Med__Progression of lipase activity and pancreatic lipase immunoreactivity in dogs hospitalized for acute pancreatitis and correlation with clinical features
Cui_2022_Front.Chem_10_1063284Butenolide derivatives from Aspergillus terreus selectively inhibit butyrylcholinesterase
Cui_2022_Front.Pharmacol_13_1002871New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors
Cui_2022_Front.Physiol_13_885030Integrated Proteomic and Metabolomic Analyses of Chicken Ovary Revealed the Crucial Role of Lipoprotein Lipase on Lipid Metabolism and Steroidogenesis During Sexual Maturity
Cui_2022_Methods.Mol.Biol_2397_179Using Molecular Simulation to Guide Protein Engineering for Biocatalysis in Organic Solvents
Cui_2022_Microbiol.Spectr__e0102722The Cell-Cell Communication Signal Indole Controls the Physiology and Interspecies Communication of Acinetobacter baumannii
Cui_2022_Oxid.Med.Cell.Longev_2022_2122856Plin5, a New Target in Diabetic Cardiomyopathy
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Khajuria_2022_Pathogens_12_Secretomic Insights into the Pathophysiology of Venturia inaequalis: The Causative Agent of Scab, a Devastating Apple Tree Disease
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Khalil_2022_Neurotoxicol__Selenium nanoparticles impart robust neuroprotection against deltamethrin-induced neurotoxicity in male rats by reversing behavioral alterations, oxidative damage, apoptosis, and neuronal loss
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Khan_2022_Micromachines.(Basel)_13_Monotheca buxifolia Driven Synthesis of Zinc Oxide Nano Material Its Characterization and Biomedical Applications
Khan_2022_Molecules_27_Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Studies of Indole Based Thiadiazole Derivatives as Dual Inhibitor of Acetylcholinesterase and Butyrylchloinesterase
Khan_2022_Pharmaceuticals.(Basel)_15_Anti-Alzheimer and Antioxidant Effects of Nelumbo nucifera L. Alkaloids, Nuciferine and Norcoclaurine in Alloxan-Induced Diabetic Albino Rats
Khan_2022_Pharmaceuticals.(Basel)_16_Synthesis and Evaluation of Novel S-alkyl Phthalimide- and S-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase
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Leuci_2022_Molecules_27_A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE)
Li_2022_ACS.Appl.Bio.Mater__Molecular Basis of the Reinforced Effect of Berberine against Cutinase from Colletotrichum capsisi by Supplying Sodium Stearate as Dispersant
Li_2022_ACS.Appl.Mater.Interfaces__Carbon Dot-Anchored Cobalt Oxyhydroxide Composite-Based Hydrogel Sensor for On-Site Monitoring of Organophosphorus Pesticides
Li_2022_ACS.Chem.Neurosci__Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease
Li_2022_Anal.Chem__In Situ Formation of o-Phenylenediamine Cascade Polymers Mediated by Metal-Organic Framework Nanozymes for Fluorescent and Photothermal Dual-Mode Assay of Acetylcholinesterase Activity
Li_2022_Anim.Biotechnol__1Overexpression of ATGL impairs lipid droplet accumulation by accelerating lipolysis in goat mammary epithelial cells
Li_2022_Anim.Nutr_11_38Probiotic effect of ferulic acid esterase-producing Lactobacillus plantarum inoculated alfalfa silage on digestion, antioxidant, and immunity status of lactating dairy goats
Li_2022_Annu.Rev.Entomol_67_1Pest Biological Control: Goals Throughout My Life
Li_2022_BMC.Genomics_23_185Characterization of pectin methylesterase gene family and its possible role in juice sac granulation in navel orange (Citrus sinensis Osbeck)
Li_2022_BMC.Pulm.Med_22_192Peroxiredoxin 6 mediates the protective function of curcumin pretreatment in acute lung injury induced by serum from patients undergoing one-lung ventilation in vitro
Li_2022_Biochem.Biophys.Res.Commun_626_100Structural insight and engineering of a plastic degrading hydrolase Ple629
Li_2022_Biorxiv__Development of esterase-resistant and highly active ghrelin analogs via thiol-ene click chemistry
Li_2022_Biosens.Bioelectron_220_114890Portable hydrogel test kit integrated dual-emission coordination polymer nanocomposite for on-site detection of organophosphate pesticides
Li_2022_Biotechnol.Adv__108026Delineating biosynthesis of Huperzine A, A plant-derived medicine for the treatment of Alzheimer's disease
Li_2022_Br.J.Cancer__The dark side of synaptic proteins in tumours
Li_2022_Bull.Entomol.Res__1Identification and expression patterns of candidate carboxylesterases in Carposina sasakii Matsumura (Lepidoptera: Carposinidae), an important pest of fruit trees
Li_2022_Cell.Chem.Biol_29_883Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling
Li_2022_Cell.Metab__Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis
Li_2022_Cells_11_Modulation of Trans-Synaptic Neurexin-Neuroligin Interaction in Pathological Pain
Li_2022_Comput.Struct.Biotechnol.J_20_459Computational design of a cutinase for plastic biodegradation by mining molecular dynamics simulations trajectories
Li_2022_Drug.Des.Devel.Ther_16_3557Semaglutide May Alleviate Hepatic Steatosis in T2DM Combined with NFALD Mice via miR-5120/ABHD6
Li_2022_Endocr.J__Does butyrylcholinesterase mediate exercise-induced and meal-induced suppression in acylated ghrelin?
Li_2022_Environ.Int_169_107522Insight into the uptake and metabolism of a new insecticide cyetpyrafen in plants
Li_2022_Environ.Sci.Technol__Identification of Novel Organophosphate Esters in Hydroponic Lettuces (Lactuca sativa L.): Biotransformation and Acropetal Translocation
Li_2022_Environ.Toxicol.Pharmacol_97_104016Bioaccumulation and toxicity of terbuthylazine in earthworms (Eisenia fetida)
Li_2022_Eur.J.Med.Chem_239_114510A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement
Li_2022_Eur.J.Med.Chem_244_114841Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease
Li_2022_Fish.Shellfish.Immunol_S1050-4648_00352Characterization of 4 deletion mutants of Pseudomonas plecoglossicida and their potential for live attenuated vaccines in large yellow croaker (Larimichthys crocea)
Li_2022_Food.Res.Int_157_111243Effect of industrial processing on the volatiles, enzymes and lipids of wholegrain and rolled oats
Li_2022_Foods_11_4069Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols
Li_2022_Front.Bioeng.Biotechnol_10_835847Two Extracellular Poly(sigma-caprolactone)-Degrading Enzymes From Pseudomonas hydrolytica sp. DSWY01(T): Purification, Characterization, and Gene Analysis
Li_2022_Front.Bioeng.Biotechnol_10_894046Synthesis of Poly(Hexamethylene Succinate-Co-Ethylene Succinate) Copolymers With Different Physical Properties and Enzymatic Hydrolyzability by Regulating the Ratio of Monomer
Li_2022_Front.Cardiovasc.Med_9_959916Association between CES1 rs2244613 and the pharmacokinetics and safety of dabigatran: Meta-analysis and quantitative trait loci analysis
Li_2022_Front.Genet_13_831133Case Report: Next-Generation Sequencing Identified a Novel Pair of Compound-Heterozygous Mutations of LPL Gene Causing Lipoprotein Lipase Deficiency
Li_2022_Front.Microbiol_13_1088581Characterization of a novel thermostable alkaline lipase derived from a compost metagenomic library and its potential application in the detergent industry
Li_2022_Front.Microbiol_13_853744Identification and Comparative Genomic Analysis of Type VI Secretion Systems and Effectors in Klebsiella pneumoniae
Li_2022_Front.Nutr_9_961697Therapeutic targets and functions of curcumol against COVID-19 and colon adenocarcinoma
Li_2022_Front.Pharmacol_13_940999Therapeutic effects of total saikosaponins from Radix bupleuri against Alzheimer's disease
Li_2022_Front.Physiol_13_1016582A full-length transcriptome and gene expression analysis of three detoxification gene families in a predatory stink bug, Picromerus lewisi
Li_2022_Front.Physiol_13_826314The Molecular Brakes of Adipose Tissue Lipolysis
Li_2022_Front.Physiol_13_877153Enhanced Degradation of Juvenile Hormone Promotes Reproductive Diapause in the Predatory Ladybeetle Coccinella Septempunctata
Li_2022_J.Agric.Food.Chem_70_5794Overexpression of PxalphaE14 Contributing to Detoxification of Multiple Insecticides in Plutella xylostella (L.)
Li_2022_J.Agric.Food.Chem_70_7626Biodegradation Pathway and Detoxification of beta-cyfluthrin by the Bacterial Consortium and Its Bacterial Community Structure
Li_2022_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1190_123101A sensitive approach for screening acetylcholinesterase inhibition of water samples using ultra-performance liquid chromatography-tandem mass spectrometry
Li_2022_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1208_123381Simultaneous measurement of six biomarkers of dichlorvos in blood by ultra performance liquid chromatography-quadrupole/electrostatic field orbitrap mass spectrometry
Li_2022_J.Enzyme.Inhib.Med.Chem_37_2099Fluorosulfate-containing pyrazole heterocycles as selective BuChE inhibitors: structure-activity relationship and biological evaluation for the treatment of Alzheimer's disease
Li_2022_J.Ethnopharmacol__115460Anti-Alzheimer's disease active components screened out and identified from Hedyotis diffusa combining bioaffinity ultrafiltration LC-MS with acetylcholinesterase
Li_2022_J.Food.Biochem__e14068Network pharmacology-based approach to investigate the mechanisms of Zingiber officinale Roscoe in the treatment of neurodegenerative diseases
Li_2022_J.Hazard.Mater_432_128660Ratiometric fluorescent hydrogel for point-of-care monitoring of organophosphorus pesticide degradation
Li_2022_J.Int.Med.Res_50_3000605221093303Negative correlation between early recovery and lipoprotein-associated phospholipase A2 levels after intravenous thrombolysis
Li_2022_J.Neuroinflammation_19_131Interleukin-6 and YKL-40 predicted recurrent stroke after ischemic stroke or TIA: analysis of 6 inflammation biomarkers in a prospective cohort study
Li_2022_J.Toxicol.Environ.Health.A__1Biological activities and gene expression of detoxifying enzymes in Tribolium castaneum induced by Moutan cortex essential oil
Li_2022_JCI.Insight__Interfering with lipid metabolism through targeting CES1 sensitizes hepatocellular carcinoma for chemotherapy
Li_2022_Life.Sci.Alliance_5_Adipose tissue-specific ablation of Ces1d causes metabolic dysregulation in mice
Li_2022_Med.Oncol_39_250PRDX6 knockout restrains the malignant progression of intrahepatic cholangiocarcinoma
Li_2022_Metab.Brain.Dis__Alzheimer's disease therapy based on acetylcholinesterase inhibitor/blocker effects on voltage-gated potassium channels
Li_2022_Methods.Mol.Biol_2474_47Acetylcholinesterase Inhibition Assays for High-Throughput Screening
Li_2022_Mini.Rev.Med.Chem__Evodiamine-A Privileged Structure with Broad-Ranging Biological Activities
Li_2022_Mol.Metab__101597Endocannabinoids regulate cocaine-associated memory through brain AEA-CB1R signalling activation
Li_2022_Mol.Psychiatry__Genome-wide association study meta-analysis of suicide death and suicidal behavior
Li_2022_Molecules_27_Preparation and Characterization of Magnetic Metal-Organic Frameworks Functionalized by Ionic Liquid as Supports for Immobilization of Pancreatic Lipase
Li_2022_NPJ.Biofilms.Microbiomes_8_39Patatin-like phospholipase CapV in Escherichia coli - morphological and physiological effects of one amino acid substitution
Li_2022_Neurotoxicol__Integrated Strategy of Network Pharmacology and in vitro Screening to Identify Mechanism of Diazinon-induced Hippocampal Neurotoxicity
Li_2022_Pestic.Biochem.Physiol_185_105150Differences in susceptibility to chlorantraniliprole between Chilo suppressalis (Lepidoptera: Crambidae) and two dominant parasitic wasps collected from Sichuan Province, China
Li_2022_Plant.Cell.Rep_41_2089The strigolactone receptor SlDWARF14 plays a role in photosynthetic pigment accumulation and photosynthesis in tomato
Li_2022_Plant.Commun_3_100303The strigolactone receptor D14 targets SMAX1 for degradation in response to GR24 treatment and osmotic stress
Li_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2209149119VpdC is a ubiquitin-activated phospholipase effector that regulates Legionella vacuole expansion during infection
Li_2022_RSC.Adv_12_35477A carboxylesterase-activatable near-infrared phototheranostic probe for tumor fluorescence imaging and photodynamic therapy
Li_2022_RSC.Adv_12_7911Facile preparation of fluorescent water-soluble non-conjugated polymer dots and fabricating an acetylcholinesterase biosensor
Li_2022_Sheng.Wu.Gong.Cheng.Xue.Bao_38_207[Characterization of Humicola insolens cutinase-tachystatin A2 fusion protein and its application in treatment of recycled paper stickies]
Li_2022_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_274_121097Redox-regulated synthesis of fluorescent polydopamine nanoparticles for detection of butyrylcholinesterase activity
Li_2022_Talanta_252_123867Ultrasensitive Acetylcholinesterase detection based on a surface-enhanced Raman scattering lever strategy for identifying nerve fibers
Li_2022_Toxicol.Lett_358_100Effects of chlorpyrifos on transient receptor potential channels
Li_2022_Toxins.(Basel)_14_Biodegradation of Fumonisins by the Consecutive Action of a Fusion Enzyme
Li_2022_Zhongguo.Zhong.Yao.Za.Zhi_47_2759[Mechanism of Shenxiong Glucose Injection against myocardial ischemia-reperfusion injury based on network pharmacology and molecular docking]
Lian_2022_Metab.Brain.Dis__Protective effects of isofraxidin against scopolamine-induced cognitive and memory impairments in mice involve modulation of the BDNF-CREB-ERK signaling pathway
Liang_2022_Antioxidants.(Basel)_11_Bioactive Components from Ampelopsis japonica with Antioxidant, Anti-alpha-Glucosidase, and Antiacetylcholinesterase Activities
Liang_2022_Fish.Shellfish.Immunol__Identification and characterization of two types of triacylglycerol lipase genes from Neocaridina denticulata sinensis
Liang_2022_Fitoterapia__105400Two new iridoids and triterpenoid analogues from the leaves of Viburnum chingii and their anti-acetylcholinesterase activity
Liang_2022_J.Ethnopharmacol__115656Carthamus tinctorius L.: A natural neuroprotective source for anti-Alzheimer's disease drugs
Liang_2022_Mol.Ther.Nucleic.Acids_28_114The Aptamer Ob2, a novel AChE inhibitor, restores cognitive deficits and alleviates amyloidogenesis in 5FAD transgenic mice
Liang_2022_Sci.Total.Environ__155747Evaluation of the toxicity effects of microplastics and cadmium on earthworms
Liao_2022_Foods_11_Inhibitory Mechanism of Baicalein on Acetylcholinesterase: Inhibitory Interaction, Conformational Change, and Computational Simulation
Liao_2022_Molecules_27_Exploring the Inhibition of Quercetin on Acetylcholinesterase by Multispectroscopic and In Silico Approaches and Evaluation of Its Neuroprotective Effects on PC12 Cells
Liaw_2022_Microorganisms_10_2403Molecular Cloning and Characterization of a New Family VI Esterase from an Activated Sludge Metagenome
Liew_2022_Sci.Rep_12_2850Thermophiles and carbohydrate-active enzymes (CAZymes) in biofilm microbial consortia that decompose lignocellulosic plant litters at high temperatures
Lim_2022_Am.J.Vet.Res_83_Lipases: it's not just pancreatic lipase!
Lim_2022_Int.J.Mol.Sci_23_Identification of Novel Natural Product Inhibitors against Matrix Metalloproteinase 9 Using Quantum Mechanical Fragment Molecular Orbital-Based Virtual Screening Methods
Lim_2022_J.Am.Vet.Med.Assoc_260_1249Understanding lipase assays in the diagnosis of pancreatitis in veterinary medicine
Lim_2022_Molecules_27_The Attenuating Effect of Beta-Carotene on Streptozotocin Induced Diabetic Vascular Dementia Symptoms in Rats
Lin_2022_3.Biotech_12_341Lactobacillus delbrueckii subsp. bulgaricus strain TCI904 reduces body weight gain, modulates immune response, improves metabolism and anxiety in high fat diet-induced obese mice
Lin_2022_Aquat.Toxicol_248_106197Toxic effects of waterborne benzylparaben on the growth, antioxidant capacity and lipid metabolism of Nile tilapia (Oreochromis niloticus)
Lin_2022_BMC.Neurol_22_242Anti-dipeptidyl-peptidase-like protein 6 encephalitis with pure cerebellar ataxia: a case report
Lin_2022_Biomed.Res.Int_2022_7483911Screening Potential Diagnostic Biomarkers for Age-Related Sarcopenia in the Elderly Population by WGCNA and LASSO
Lin_2022_Ecotoxicol.Environ.Saf_248_114301Multiple acetylcholinesterases in Pardosa pseudoannulata brain worked collaboratively to provide protection from organophosphorus insecticides
Lin_2022_Int.J.Mol.Sci_23_The Citrus Flavonoid Nobiletin Downregulates Angiopoietin-like Protein 3 (ANGPTL3) Expression and Exhibits Lipid-Modulating Effects in Hepatic Cells and Adult Zebrafish Models
Lin_2022_J.Agric.Food.Chem_70_13349Enzymatic Cleavage of Diferuloyl Cross-Links in Corn Bran Arabinoxylan by Two Bacterial Feruloyl Esterases
Lin_2022_Mol.Med.Rep_25_Knockdown of DPP4 promotes the proliferation and the activation of the CREB/aromatase pathway in ovarian granulosa cells
Lin_2022_Neurobiol.Dis_174_105887Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice
Lin_2022_Nutrients_14_The Comparative Analysis of Genomic Diversity and Genes Involved in Carbohydrate Metabolism of Eighty-Eight Bifidobacterium pseudocatenulatum Isolates from Different Niches of China
Lindgren_2022_Chemistry__Broad-spectrum antidote discovery by untangling the reactivation mechanism of nerve agent inhibited acetylcholinesterase
Lins_2022_Chem.Biol.Interact__110136BChE inhibitors from marine organisms - A review
Lipinski_2022_Int.J.Mol.Sci_23_Fentanyl Structure as a Scaffold for Opioid/Non-Opioid Multitarget Analgesics
Lista_2022_Ageing.Res.Rev__101819Determinants of approved acetylcholinesterase inhibitor response outcomes in Alzheimer's disease: relevance for precision medicine in neurodegenerative diseases
Listos_2022_Molecules_27_Linagliptin, a Selective Dipeptidyl Peptidase-4 Inhibitor, Reduces Physical and Behavioral Effects of Morphine Withdrawal
Lite_2022_Environ.Toxicol__Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety-like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae
Liu_2022_Anal.Chem__Metal-Organic Frameworks-Based Immobilized Enzyme Microreactors Integrated with Capillary Electrochromatography for High-Efficiency Enzyme Assay
Liu_2022_Anal.Chim.Acta_1221_340126A highly sensitive and selective enzyme activated fluorescent probe for in vivo profiling of carboxylesterase 2
Liu_2022_Aquat.Toxicol_245_106118Effects of short-term exposure to tralopyril on physiological indexes and endocrine function in turbot (Scophthalmus maximus)
Liu_2022_BMC.Anesthesiol_22_267The effect of neostigmine on postoperative delirium after colon carcinoma surgery: a randomized, double-blind, controlled trial
Liu_2022_BMC.Cardiovasc.Disord_22_177The benefit of exercise rehabilitation guided by 6-minute walk test on lipoprotein-associated phospholipase A2 in patients with coronary heart disease undergoing percutaneous coronary intervention: a prospective randomized controlled study
Liu_2022_BMC.Med_20_45Personalised treatment for cognitive impairment in dementia: development and validation of an artificial intelligence model
Liu_2022_Biochem.Pharmacol_204_115224Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus
Liu_2022_Biochem.Pharmacol__115250Emerging role of carboxylesterases in nonalcoholic fatty liver disease
Liu_2022_Biochim.Biophys.Acta.Mol.Basis.Dis__166620Hesperidin methyl chalcone ameliorates lipid metabolic disorders by activating lipase activity and increasing energy metabolism
Liu_2022_Bioorg.Chem_126_105875Discovery of novel tacrine derivatives as potent antiproliferative agents with CDKs inhibitory property
Liu_2022_Bioorg.Chem_129_106168Discovery of novel beta-carboline-1,2,3-triazole hybrids as AChE/GSK-3beta dual inhibitors for Alzheimer's disease treatment
Liu_2022_Bioorg.Med.Chem_58_116660Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer's disease
Liu_2022_Bioorg.Med.Chem_78_117146Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids
Liu_2022_Biosens.Bioelectron_211_114392New fluorescent probe with recognition moiety of bipiperidinyl reveals the rise of hepatocellular carboxylesterase activity during heat shock
Liu_2022_Biotechnol.Biofuels.Bioprod_15_127Selfish uptake versus extracellular arabinoxylan degradation in the primary degrader Ruminiclostridium cellulolyticum, a new string to its bow
Liu_2022_Chem.Commun.(Camb)__An esterase-activatable curcumin prodrug for tumor-targeting therapy
Liu_2022_Comb.Chem.High.Throughput.Screen__Anti-ischemic effect of monoterpene citronellol on experimental stroke models mediated by proinflammatroy cytokines
Liu_2022_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_260_109406The physiological, biochemical and transcriptional responses to sulfamethoxazole in the Asian clam, Corbicula fluminea (O. F. Muller, 1774)
Liu_2022_Curr.Alzheimer.Res__Co-treatment with the herbal medicine SIP3 and donepezil improves memory and depression in the mouse model of Alzheimer's disease
Liu_2022_Dev.Comp.Immunol_132_104410The juvenile hormone epoxide hydrolase homolog in Penaeus vannamei plays immune-related functions
Liu_2022_Environ.Sci.Pollut.Res.Int__Fosthiazate exposure induces oxidative stress, nerve damage, and reproductive disorders in nontarget nematodes
Liu_2022_Enzyme.Microb.Technol_156_110004Enhancement of PET biodegradation by anchor peptide-cutinase fusion protein
Liu_2022_Eur.J.Med.Chem_235_114305Novel inhibitors of AChE and Abeta aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease
Liu_2022_Eur.J.Med.Chem_242_114689Design, synthesis and biological evaluation of novel coumarin derivatives as multifunctional ligands for the treatment of Alzheimer's disease
Liu_2022_Food.Addit.Contam.Part.A.Chem.Anal.Control.Expo.Risk.Assess__FumDSB can alleviate the inflammatory response induced by fumonisin B(1) in growing pigs
Liu_2022_Food.Chem_406_134506Monoacylglycerol lipase from marine Geobacillus sp. showing lysophospholipase activity and its application in efficient soybean oil degumming
Liu_2022_Foods_12_The Chemical Composition Characteristics and Health Risk Assessment of Cooking Fume Condensates from Residential Kitchens in Different Regions of China
Liu_2022_Front.Aging.Neurosci_14_922650A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer's Disease by Dual Inhibition of Acetylcholinesterase and Inflammation
Liu_2022_Front.Bioeng.Biotechnol_10_865787Catalytic Features and Thermal Adaptation Mechanisms of a Deep Sea Bacterial Cutinase-Type Poly(Ethylene Terephthalate) Hydrolase
Liu_2022_Front.Biosci.(Landmark.Ed)_27_71Cucurbitacin B exerts neuroprotection in a murine Alzheimer's disease model by modulating oxidative stress, inflammation, and neurotransmitter levels
Liu_2022_Front.Cell.Infect.Microbiol_12_1052466Identification of novel immune-related targets mediating disease progression in acute pancreatitis
Liu_2022_Front.Chem_10_996641An artificial self-assembling peptide with carboxylesterase activity and substrate specificity restricted to short-chain acid p-nitrophenyl esters
Liu_2022_Front.Microbiol_13_855658Characterization of a Novel Esterase Est33 From an Antarctic Bacterium: A Representative of a New Esterase Family
Liu_2022_Front.Nutr_9_1016020Sweet potato extract alleviates high-fat-diet-induced obesity in C57BL/6J mice, but not by inhibiting pancreatic lipases
Liu_2022_Front.Physiol_13_1054769Effects of larval exposure to the insecticide flumethrin on the development of honeybee (Apis mellifera) workers
Liu_2022_Front.Vet.Sci_9_1079580Subchronic toxicity of oral deltamethrin in laying chickens
Liu_2022_Int.J.Mol.Sci_23_Molecular Mechanisms Underlying Metabolic Resistance to Cyflumetofen and Bifenthrin in Tetranychus urticae Koch on Cowpea
Liu_2022_J.Biotechnol__Enhanced biodegradation activity towards poly(ethyl acrylate) and poly(vinyl acetate) by anchor peptide assistant targeting
Liu_2022_J.Chem.Inf.Model_62_1933In Silico Investigation on KAR Signaling Reveals the Significant Dynamic Change of Its Receptor's Structure
Liu_2022_J.Chromatogr.A_1665_462824Hollow urchin-shaped manganese dioxide microspheres immobilized acetylcholinesterase for rapid screening inhibitors from traditional herbal medicines
Liu_2022_J.Environ.Sci.Health.B__1Graphitic-phase C(3)N(4) nanosheets combined with MnO(2) nanosheets for sensitive fluorescence quenching detection of organophosphorus pesticides
Liu_2022_J.Immunol.Res_2022_6051092BCHE as a Prognostic Biomarker in Endometrial Cancer and Its Correlation with Immunity
Liu_2022_J.Plant.Res__Strigolactone is involved in nitric oxide-enhanced the salt resistance in tomato seedlings
Liu_2022_J.Sep.Sci__Extraction and preparation of 5-lipoxygenase and acetylcholinesterase inhibitors from Astragalus membranaceus stems and leaves
Liu_2022_J.Transl.Med_20_418Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins
Liu_2022_Methods.Mol.Biol_2492_117A Three-Dimensional Brain-on-a-Chip Using Human iPSC-Derived GABAergic Neurons and Astrocytes
Liu_2022_Microb.Cell.Fact_21_97Display of a novel carboxylesterase CarCby on Escherichia coli cell surface for carbaryl pesticide bioremediation
Liu_2022_Molecules_27_Synthesis, Characterization and Biological Evaluation of Benzothiazole-Isoquinoline Derivative
Liu_2022_Nanomaterials.(Basel)_12_Highly Selective Detection of Paraoxon in Food Based on the Platform of Cu Nanocluster/MnO(2) Nanosheets
Liu_2022_Nat.Cancer__Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress
Liu_2022_Nat.Commun_13_3490Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction
Liu_2022_Pest.Manag.Sci__Synthesis, insecticidal activity, and mode of action of novel imidazopyridine mesoionic derivatives containing an amido group
Liu_2022_Plant.Cell_34_3301Dwarf and High Tillering1 represses rice tillering through mediating the splicing of D14 pre-mRNA
Liu_2022_Plant.Foods.Hum.Nutr__Insight into Isolation and Characterization of Phenolic Compounds from Hawthorn (Crataegus pinnatifida Bge.) with Antioxidant, Anti-Acetylcholinesterase, and Neuroprotective Activities
Liu_2022_Protein.Expr.Purif__106165Enhancing the secretion of a feruloyl esterase in Bacillus subtilis by signal peptide screening and rational design
Liu_2022_Rapid.Commun.Mass.Spectrom__e9332Detoxification mechanism of vinegar-processed Kansui revealed by systematic phytochemical analysis using UPLC-DAD-MS/MS, UPLC-HR-MS and in silico drug target identification
Liu_2022_Sci.Rep_12_13649Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors
Liu_2022_Sci.Rep_12_16609Independent association of Lp(a) with platelet reactivity in subjects without statins or antiplatelet agents
Liu_2022_Sci.Rep_12_3531Association between long-term usage of acetylcholinesterase inhibitors and lung cancer in the elderly: a nationwide cohort study
Lize_2022_Environ.Res__113348Prenatal exposure to organophosphate pesticides and autism spectrum disorders in 11-year-old children in the French PELAGIE cohort
Llamas-Garcia_2022_ACS.Omega_7_12643Improved Stability of Human CGI-58 Induced by Phosphomimetic S237E Mutation
Llanes_2022_Curr.Med.Chem__Anticholinesterase agents for Alzheimer's Disease treatment: an updated overview
Llorent-Martinez_2022_Molecules_27_New Biological and Chemical Evidences of Two Lamiaceae Species (Thymbra capitata and Thymus sipyleus subsp. rosulans): In Vitro, In Silico and Ex Vivo Approaches
Lo Verde_2022_Food.Res.Int_162_111996A highly active esterase from Lactobacillus helveticus hydrolyzes chlorogenic acid in sunflower meal to prevent chlorogenic acid induced greening in sunflower protein isolates
Loer_2022_Pharmaceutics_14_Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug-Drug-Gene Interaction Predictions
Loewenthal_2022_Anal.Chem__Monitoring the Activity and Inhibition of Cholinesterase Enzymes using Single-Walled Carbon Nanotube Fluorescent Sensors
Lolak_2022_Mol.Divers__Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors
Lombardi_2022_Eur.J.Clin.Pharmacol__Long-term use of pharmacological treatment in Alzheimer's disease: a retrospective cohort study in real-world clinical practice
Lomwongsopon_2022_Polymers.(Basel)_14_Critical Review on the Progress of Plastic Bioupcycling Technology as a Potential Solution for Sustainable Plastic Waste Management
Long_2022_Chem.Biodivers__e202100925Asperbenzophenone A and Versicolamide C, New Fungal Metabolites from the Soft Coral Derived Aspergillus sp. SCSIO 41036
Long_2022_Front.Nutr_9_852012Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats
Lopes_2022_Chem.Biol.Drug.Des__Evaluation of the Histamine H(3) Receptor Antagonists from LINS01 Series as Cholinesterases Inhibitors - Enzymatic and Modeling Studies
Loring_2022_Molecules_27_Speculation on How RIC-3 and Other Chaperones Facilitate alpha7 Nicotinic Receptor Folding and Assembly
Lorusso_2022_Chemosphere__136594Carbon nanomaterial functionalization with pesticide-detoxifying carboxylesterase
Losada-Perez_2022_PLoS.Genet_18_e1010329Synaptic components are required for glioblastoma progression in Drosophila
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Shabbir_2022_Curr.Med.Chem__Neuroprotective potential of curcuminoids in modulating Alzheimer's Disease via multiple signaling pathways
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Shamarao_2022_Food.Funct__Antiobesity drug-likeness properties and pancreatic lipase inhibition of a novel low molecular weight lutein oxidized product, LOP6
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Shan_2022_Int.J.Mol.Sci_23_alpha/beta-Hydrolase D16B Truncation Results in Premature Sperm Capacitation in Cattle
Shang_2022_Neoplasma__Endothelial lipase promotes acute myeloid leukemia progression through metabolic reprogramming
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Xu_2022_Biomed.Pharmacother_153_113495Activation of cholinergic basal forebrain neurons improved cognitive functions in adult-onset hypothyroid mice
Xu_2022_Biomed.Pharmacother_156_113847The monoacylglycerol lipase inhibitor, JZL184, has comparable effects to therapeutic hypothermia, attenuating global cerebral injury in a rat model of cardiac arrest
Xu_2022_Cells_11_Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms
Xu_2022_Diabetes.Obes.Metab__Efficacy and safety of DBPR108 (prusogliptin) as an add-on to metformin therapy in patients with type 2 diabetes mellitus: A 24-week, multi-center, randomized, double-blind, placebo-controlled, superiority, phase III clinical trial
Xu_2022_Environ.Pollut__119562Biochemical toxicity and transcriptome aberration induced by dinotefuran in Bombyx mori
Xu_2022_Fitoterapia_163_105327Chemical constituents from Daphne giraldii and their cytotoxicities and inhibitory activities against acetylcholinesterase
Xu_2022_Food.Chem_382_132106Analysis of the binding selectivity and inhibiting mechanism of chlorogenic acid isomers and their interaction with grass carp endogenous lipase using multi-spectroscopic, inhibition kinetics and modeling methods
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Xu_2022_Microb.Biotechnol__Application of a novel fluorogenic polyurethane analogue probe in polyester-degrading microorganisms screening by microfluidic droplet
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Xu_2022_Nutrients_14_Distinct AMPK-Mediated FAS/HSL Pathway Is Implicated in the Alleviating Effect of Nuciferine on Obesity and Hepatic Steatosis in HFD-Fed Mice
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Xu_2022_Plant.Physiol__A maize triacylglycerol lipase inhibits sugarcane mosaic virus infection
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Yadav_2022_J.Cell.Biochem__An in-silico investigation of fluoride ions impact on pancreatic lipase
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Yuan_2022_Biomed.Chromatogr__e5380Development and validation of a LC-MS/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and diabetic nephropathy mice
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Zhang_2022_Biomed.Pharmacother_155_113704The dipeptidyl peptidase-4 inhibitor linagliptin ameliorates LPS-induced acute lung injury by maintenance of pulmonary microvascular barrier via activating the Epac1/AKT pathway
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Zhang_2022_Bioorg.Chem_125_105844Carbamate-based N-Substituted tryptamine derivatives as novel pleiotropic molecules for Alzheimer's disease
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Zhang_2022_Cells_11_Mitigation of Memory Impairment with Fermented Fucoidan and lambda-Carrageenan Supplementation through Modulating the Gut Microbiota and Their Metagenome Function in Hippocampal Amyloid-beta Infused Rats
Zhang_2022_Chem.Biol.Interact_365_110097In vitro evaluation of the impact of Covid-19 therapeutic agents on the hydrolysis of the antiviral prodrug remdesivir
Zhang_2022_Ecotoxicol.Environ.Saf_236_113482Sublethal effects of tolfenpyrad on the development, reproduction, and predatory ability of Chrysoperla sinica
Zhang_2022_Eur.J.Med.Chem_240_114606Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease
Zhang_2022_Eur.J.Med.Chem_242_114695Recent advance on pleiotropic cholinesterase inhibitors bearing amyloid modulation efficacy
Zhang_2022_Eur.J.Pharmacol_940_175478Administration of Huperzine A microspheres ameliorates myocardial ischemic injury via alpha7nAChR-dependent JAK2/STAT3 signaling pathway
Zhang_2022_Eur.Rev.Med.Pharmacol.Sci_26_1183Pharmacokinetics of HupA-PLGA-NPs of different sizes in the mouse blood and brain determined by LC-MS/MS
Zhang_2022_Evid.Based.Complement.Alternat.Med_2022_4778163The Effect of Guilingji Capsules on Vascular Mild Cognitive Impairment: A Randomized, Double-Blind, Controlled Trial
Zhang_2022_Food.Chem_382_132302Lipase-catalyzed one-step regioselective synthesis of 1,2-dioctanoylgalloylglycerol in a solvent-free system: Optimization of reaction conditions and structural elucidation
Zhang_2022_Food.Chem_395_133547Modulation of oxidative stress and gut microbiota by selenium-containing peptides from Cardamine enshiensis and structural-based characterization
Zhang_2022_Food.Chem_399_133982Chain-locked precursor ion scanning based HPLC-MS/MS for in-depth molecular analysis of lipase-catalyzed transesterification of structured phospholipids containing -3 fatty acyl chains
Zhang_2022_Food.Sci.Nutr_10_3Hepatitis B virus genotype is an independent prognostic factor of telbivudine and tenofovir treatment in hepatitis B surface antigen-positive pregnant women
Zhang_2022_Food.Sci.Nutr_10_487UHPLC-QTOF/MS-based comparative metabolomics in pectoralis major of fast- and slow-growing chickens at market ages
Zhang_2022_Front.Bioeng.Biotechnol_10_1034972Genetic manipulation of the interconversion between diacylglycerols and triacylglycerols in Rhodosporidium toruloides
Zhang_2022_Front.Bioeng.Biotechnol_10_824300Gram-Scale Synthesis of (R)-P-Chlorophenyl-1,2-Ethanediol at High Concentration by a Pair of Epoxide Hydrolases
Zhang_2022_Front.Endocrinol.(Lausanne)_13_1067529Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders
Zhang_2022_Front.Oncol_12_944025Recent Advances on the Role of ATGL in Cancer
Zhang_2022_Front.Plant.Sci_13_1041733Transcriptomic and metabolomic analyses reveal the antifungal mechanism of the compound phenazine-1-carboxamide on Rhizoctonia solani AG1IA
Zhang_2022_Front.Vet.Sci_9_909039Genome-Wide Detection of Copy Number Variations and Evaluation of Candidate Copy Number Polymorphism Genes Associated With Complex Traits of Pigs
Zhang_2022_Insect.Sci__Characterization of neutral lipases revealed the tissue-specific TAG hydrolytic activity in Nilaparvata lugens
Zhang_2022_Insects_13_Transcriptomic Identification and Expression Profile Analysis of Odorant-Degrading Enzymes from the Asian Corn Borer Moth, Ostrinia furnacalis
Zhang_2022_Int.J.Environ.Res.Public.Health_19_5-Methyltetrahydrofolate Alleviates Memory Impairment in a Rat Model of Alzheimer's Disease Induced by D-Galactose and Aluminum Chloride
Zhang_2022_Int.J.Mol.Sci_23_Huperzine-A Improved Animal Behavior in Cuprizone-Induced Mouse Model by Alleviating Demyelination and Neuroinflammation
Zhang_2022_Int.J.Mol.Sci_24_383The Functional Characterization of Carboxylesterases Involved in the Degradation of Volatile Esters Produced in Strawberry Fruits
Zhang_2022_J.Affect.Disord__Prolonged sevoflurane exposure causes abnormal synapse development and dysregulates beta-neurexin and neuroligins in the hippocampus in neonatal rats
Zhang_2022_J.Agric.Food.Chem__Molecular and Biochemical Analyses of a Novel Trifunctional Endoxylanase/Endoglucanase/Feruloyl Esterase from the Human Colonic Bacterium Bacteroides intestinalis DSM 17393
Zhang_2022_J.Appl.Toxicol__Combined effects of chlorpyrifos and cyfluthrin on neurobehavior and neurotransmitter levels in larval zebrafish
Zhang_2022_J.Clin.Lipidol__GPIHBP1 autoantibody is an independent risk factor for the recurrence of hypertriglyceridemia-induced acute pancreatitis
Zhang_2022_J.Enzyme.Inhib.Med.Chem_37_629Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1
Zhang_2022_J.Fungi.(Basel)_8_Toxicological and Biochemical Description of Synergism of Beauveria bassiana and Emamectin Benzoate against Megalurothrips usitatus (Bagrall)
Zhang_2022_J.Hazard.Mater_437_129406Biodegradation of polyester polyurethane by the marine fungus Cladosporium halotolerans 6UPA1
Zhang_2022_J.Plant.Physiol_270_153640GR24-mediated enhancement of salt tolerance and roles of H(2)O(2) and Ca(2+) in regulating this enhancement in cucumber
Zhang_2022_J.Res.Med.Sci_27_33Hemoperfusion in combination with hemofiltration for acute severe organophosphorus pesticide poisoning: A systematic review and meta-analysis
Zhang_2022_J.Toxicol.Sci_47_61Ferulic acid regulates miR-17/PTEN axis to inhibit LPS-induced pulmonary microvascular endothelial cells apoptosis through activation of PI3K/Akt pathway
Zhang_2022_Life.Sci_310_121122Role of epoxyeicosatrienoic acids in cardiovascular diseases and cardiotoxicity of drugs
Zhang_2022_Life.Sci__120743Inhibition of Radix Scutellariae flavones on carboxylesterase mediated activations of prodrugs
Zhang_2022_Mol.Genet.Genomics__Response of xenobiotic biodegradation and metabolic genes in Tribolium castaneum following eugenol exposure
Zhang_2022_Mol.Pharm__Enzyme-Activated Multifunctional Prodrug Combining Site-Specific Chemotherapy with Light-Triggered Photodynamic Therapy
Zhang_2022_Nat.Prod.Res__1Structurally diverse lignans from Solanum lyratum: chemical evidence for their acetylcholinease inhibitory activity
Zhang_2022_Oxid.Med.Cell.Longev_2022_4594956Plin5 Bidirectionally Regulates Lipid Metabolism in Oxidative Tissues
Zhang_2022_Oxid.Med.Cell.Longev_2022_5759626COX-2/sEH Dual Inhibitor PTUPB Attenuates Epithelial-Mesenchymal Transformation of Alveolar Epithelial Cells via Nrf2-Mediated Inhibition of TGF-beta1/Smad Signaling
Zhang_2022_PLoS.One_17_e0266608Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor
Zhang_2022_Pest.Manag.Sci__Toxicity, Horizontal Transfer, Physiological and Behavioral Effects of Cycloxaprid against Solenopsis invicta (Hymenoptera: Formicidae)
Zhang_2022_Pharm.Res_39_75Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases
Zhang_2022_Phytochemistry__113357Investigations of specialised metabolites of endophyte Diaporthe destruens hosted in Illigera orbiculata C. Y. Wu
Zhang_2022_Plants.(Basel)_11_Untargeted Phenolic Profiling and Functional Insights of the Aerial Parts and Bulbs of Drimia maritima (L.) Stearn
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Zhang_2022_Talanta_243_123284Rapid screening for acetylcholinesterase inhibitors in Selaginella doederleinii Hieron by using functionalized magnetic Fe(3)O(4) nanoparticles
Zhang_2022_Talanta_249_123664CoOOH nanosheets ensure ratiometric fluorescence assay of acetylcholinesterase
Zhang_2022_Toxins.(Basel)_14_816Biodegradation of Free Gossypol by Helicoverpa armigera Carboxylesterase Expressed in Pichia pastoris
Zhang_2022_Trials_23_376Comparison of the effects of neostigmine and sugammadex on postoperative residual curarization and postoperative pulmonary complications by means of diaphragm and lung ultrasonography: a study protocol for prospective double-blind randomized controlled trial
Zhang_2022_World.J.Psychiatry_12_1127Emerging role of psychosis in Parkinson's disease: From clinical relevance to molecular mechanisms
Zhao_2022_ACS.Cent.Sci_8_1424Cellular Target Deconvolution of Small Molecules Using a Selection-Based Genetic Screening Platform
Zhao_2022_ACS.Chem.Neurosci_13_2060Structural Analysis and Development of Notum Fragment Screening Hits
Zhao_2022_Anal.Biochem__114628A stable enzyme sensor via embedding enzymes into zeolitic imidazolate frameworks for pesticide determination
Zhao_2022_Analyst__A sensitive fluorescence biosensor based on metal ion-mediated DNAzyme activity for amplified detection of acetylcholinesterase
Zhao_2022_Arch.Toxicol__Inter-individual variation in chlorpyrifos toxicokinetics characterized by physiologically based kinetic (PBK) and Monte Carlo simulation comparing human liver microsome and Supersome() cytochromes P450 (CYP)-specific kinetic data as model input
Zhao_2022_Comput.Math.Methods.Med_2022_4869470NDRG4 Alleviates Myocardial Infarction-Induced Apoptosis through the JAK2/STAT3 Pathway
Zhao_2022_EMBO.Rep__e52669An RDH-Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase
Zhao_2022_Food.Chem_379_132148Green synthesis of polydopamine functionalized magnetic mesoporous biochar for lipase immobilization and its application in interesterification for novel structured lipids production
Zhao_2022_Front.Endocrinol.(Lausanne)_13_1028191Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture
Zhao_2022_Front.Microbiol_13_1107104Molecular mechanism of LIP05 derived from Monascus purpureus YJX-8 for synthesizing fatty acid ethyl esters under aqueous phase
Zhao_2022_Insects_13_The Role of Insect Symbiotic Bacteria in Metabolizing Phytochemicals and Agrochemicals
Zhao_2022_Int.J.Mol.Sci_23_The Patatin-Like Phospholipase Domain Containing Protein 7 Regulates Macrophage Classical Activation through SIRT1/NF-B and p38 MAPK Pathways
Zhao_2022_Int.J.Mol.Sci_23_5822Structural Basis for the Regiospecificity of a Lipase from Streptomyces sp. W007
Zhao_2022_J.Ethnopharmacol__115641Screening and identification of anti-acetylcholinesterase ingredients from Tianzhi granule based on ultrafiltration combined with ultra-performance liquid chromatography-mass spectrometry and in silico analysis
Zhao_2022_J.Sep.Sci__Screening of acetylcholinesterase inhibitory and antioxidant active compounds from Terminalia chebula fruits by spectrum-effect relationship and liquid chromatography-mass spectrometry analysis
Zhao_2022_JCI.Insight__Lysosomal acid lipase, CSF1R and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells
Zhao_2022_Org.Biomol.Chem__Unprecedented diterpenoid dimers with soluble epoxide hydrolase inhibitory effect from Euphorbia fischeriana
Zhao_2022_Pestic.Biochem.Physiol_183_105057Transcriptome analysis and the identification of genes involved in the metabolic pathways of fenoxaprop-P-ethyl in rice treated with isoxadifen-ethyl hydrolysate
Zhao_2022_Theor.Appl.Genet__Correction to: Mutation in BrGGL7 gene encoding a GDSL esterase/lipase causes male sterility in Chinese cabbage (Brassica rapa L. ssp. pekinensis)
Zheng_2022_Anal.Chim.Acta_1212_339913In-situ preparation of hollow CdCoS(2) heterojunction with enhanced photocurrent response for highly photoelectrochemical sensing of organophosphorus pesticides
Zheng_2022_Bioconjug.Chem__Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism
Zheng_2022_Ecotoxicol.Environ.Saf_232_113251Impacts of di-(2-ethylhexyl) phthalate on Folsomia candida (Collembola) assessed with a multi-biomarker approach
Zhong_2022_Bioorg.Chem_130_106224Novel AP2238-clorgiline hybrids as multi-target agents for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation
Zhou_2022_ACS.Catal_12_762Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain
Zhou_2022_AMB.Express_12_51Whole genome sequencing and analysis of fenvalerate degrading bacteria Citrobacter freundii CD-9
Zhou_2022_Aging.Clin.Exp.Res__Effect of transcutaneous auricular vagus nerve stimulation on delayed neurocognitive recovery in elderly patients
Zhou_2022_BMC.Plant.Biol_22_30Physiological mechanism of strigolactone enhancing tolerance to low light stress in cucumber seedlings
Zhou_2022_Braz.J.Med.Biol.Res_55_e12320Serum levels of IL-12, IL-18, and IL-21 are indicators of viral load in patients chronically infected with HBV
Zhou_2022_Cancers.(Basel)_14_Pancreatic Cancer Cell-Derived Exosomes Promote Lymphangiogenesis by Downregulating ABHD11-AS1 Expression
Zhou_2022_Chem.Biodivers__Two new C18-diterpenoid alkaloids from Aconitum leucostomum Worosch
Zhou_2022_Foods_11_Future of Structured Lipids: Enzymatic Synthesis and Their New Applications in Food Systems
Zhou_2022_Front.Neurosci_16_861059Diprotin A TFA Exerts Neurovascular Protection in Ischemic Cerebral Stroke
Zhou_2022_Front.Oncol_12_998500Simultaneous CSM-TACE with CalliSpheres() and partial splenic embolization using 8spheres() for hepatocellular carcinoma with hypersplenism: Early prospective multicenter clinical outcome
Zhou_2022_Front.Physiol_13_873580Juvenile Hormone Is an Important Factor in Regulating Aspongopus chinensis Dallas Diapause
Zhou_2022_J.Med.Entomol__Emerging Mosquito Resistance to Piperonyl Butoxide-Synergized Pyrethroid Insecticide and Its Mechanism
Zhou_2022_Mol.Oncol__Protein palmitoylation in cancer: molecular functions and therapeutic potential
Zhou_2022_Toxins.(Basel)_15_Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Zhu_2022_Alzheimers.Dement__Racial/ethnic disparities in initiation and persistent use of anti-dementia medications
Zhu_2022_BMC.Cardiovasc.Disord_22_481The impact of ABCB1 and CES1 polymorphisms on the safety of dabigatran in patients with non-valvular atrial fibrillation
Zhu_2022_Biochem.Biophys.Res.Commun_606_121Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats
Zhu_2022_Front.Vet.Sci_9_779745Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspring
Zhu_2022_Gene_822_146340A hypothesis-driven study to comprehensively investigate the association between genetic polymorphisms in EPHX2 gene and cardiovascular diseases: findings from the UK Biobank
Zhu_2022_Int.J.Mol.Sci_23_Discovery of the Key Mutation Site Influencing the Thermostability of Thermomyces lanuginosus Lipase by Rosetta Design Programs
Zhu_2022_J.Environ.Sci.Health.B__1Detecting the combined toxicity of 18 binary and 24 ternary pesticide combinations to carboxylesterase based on fluorescence probe technology
Zhu_2022_J.Enzyme.Inhib.Med.Chem_37_1375Design, synthesis, and evaluation of novel O-alkyl ferulamide derivatives as multifunctional ligands for treating Alzheimer's disease
Zhu_2022_J.Healthc.Eng_2022_8387458LncRNA ABHD11-AS1 Participates in the Progression of Cervical Carcinoma by Targeting miR-1254 and Is the Key to the Diagnosis and Treatment of Cervical Carcinoma in the Future
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Zhu_2022_Theor.Appl.Genet__Fine mapping of powdery mildew resistance gene MlWE74 derived from wild emmer wheat (Triticum turgidum ssp. dicoccoides) in an NBS-LRR gene cluster
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Zieniuk_2022_Molecules_27_Lipase-Catalyzed Synthesis, Antioxidant Activity, Antimicrobial Properties and Molecular Docking Studies of Butyl Dihydrocaffeate
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Zuniga-Venegas_2022_Environ.Mol.Mutagen__DNA damage in a Chilean population exposed to pesticides and its association with PON1 (Q192R and L55M) susceptibility biomarker
Zuniga_2022_Neurologia.(Engl.Ed)_37_287Pharmacogenetic studies in Alzheimer disease
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