2005

Kim_2005_J.Microbiol_43_285 Molecular characterization of extracellular medium-chain-length poly(3-hydroxyalkanoate) depolymerase genes from Pseudomonas alcaligenes strains
Galagan_2005_Nature_438_1105 Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
Romano_2005_Tetrahedron.Asymmetry_16_841 Enhanced enantioselectivity of Bacillus coagulans in the hydrolysis of 1,2-O-isopropylidene glycerol esters by thermal knock-out of undesired enzymes
Park_2005_J.Biotechnol_120_174 Stereoselective lipases from Burkholderia sp., cloning and their application to preparation of methyl (R)-N-(2,6-dimethylphenyl)alaninate, a key intermediate for (R)-Metalaxyl
Machida_2005_Nature_438_1157 Genome sequencing and analysis of Aspergillus oryzae
Yakimov_2005_Environ.Microbiol_7_1426 Natural microbial diversity in superficial sediments of Milazzo Harbor (Sicily) and community successions during microcosm enrichment with various hydrocarbons
Nielsen_2005_Biochim.Biophys.Acta_1752_124 Analysis of protein-surfactant interactions--a titration calorimetric and fluorescence spectroscopic investigation of interactions between Humicola insolens cutinase and an anionic surfactant
Nielsen_2005_Langmuir_21_4299 Interactions of Humicola insolens cutinase with an anionic surfactant studied by small-angle neutron scattering and isothermal titration calorimetry
Ternstrom_2005_Biochim.Biophys.Acta_1748_74 Unfolding and inactivation of cutinases by AOT and guanidine hydrochloride
Heinzelmann_2005_Microbiology_151_1963 An acyl-CoA dehydrogenase is involved in the formation of the Delta cis3 double bond in the acyl residue of the lipopeptide antibiotic friulimicin in Actinoplanes friuliensis
Haydock_2005_Microbiology_151_3161 Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449
McAlpine_2005_J.Nat.Prod_68_493 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example
Meyerdierks_2005_Environ.Microbiol_7_1937 Insights into the genomes of archaea mediating the anaerobic oxidation of methane
Rhee_2005_Appl.Environ.Microbiol_71_817 New thermophilic and thermostable esterase with sequence similarity to the hormone-sensitive lipase family, cloned from a metagenomic library
Zhang_2005_Artif.Cells.Blood.Substit.Immobil.Biotechnol_33_435 Purification and properties of lipases\/esterases from a Bacillus strain for enantioselective resolution of (S)-Ketoprofen
Karpushova_2005_Appl.Microbiol.Biotechnol_67_59 Cloning, recombinant expression and biochemical characterisation of novel esterases from Bacillus sp. associated with the marine sponge Aplysina aerophoba
Nunoura_2005_Environ.Microbiol_7_1967 Genetic and functional properties of uncultivated thermophilic crenarchaeotes from a subsurface gold mine as revealed by analysis of genome fragments
Nesbo_2005_Environ.Microbiol_7_2011 Lateral gene transfer and phylogenetic assignment of environmental fosmid clones
Ranjan_2005_Biochem.Biophys.Res.Commun_335_57 Isolation of novel lipolytic genes from uncultured bacteria of pond water
Sabehi_2005_PLoS.Biol_3_e273 New insights into metabolic properties of marine bacteria encoding proteorhodopsins
Brzostowicz_2005_Environ.Microbiol_7_179 Proposed involvement of a soluble methane monooxygenase homologue in the cyclohexane-dependent growth of a new Brachymonas species
Sullivan_2005_PLoS.Biol_3_E144 Three Prochlorococcus cyanophage genomes: signature features and ecological interpretations
Campbell_2005_Insect.Mol.Biol_14_121 Midgut and salivary gland transcriptomes of the arbovirus vector Culicoides sonorensis (Diptera: Ceratopogonidae)
Takagi_2005_Appl.Microbiol.Biotechnol_68_336 Characterization of [3Fe-4S] ferredoxin DbfA3, which functions in the angular dioxygenase system of Terrabacter sp. strain DBF63
Habe_2005_Microbiology_151_3713 The fluorene catabolic linear plasmid in Terrabacter sp. strain DBF63 carries the beta-ketoadipate pathway genes, pcaRHGBDCFIJ, also found in proteobacteria
Wilson_2005_Science_309_1090 Complete genome sequence and lytic phase transcription profile of a Coccolithovirus
Sujatha_2005_Indian.J.Biotechnol_4_323 Analysis of PCR products for PHB production in indigenous Pseudomonas sp. LDC-5
Awaya_2005_J.Bacteriol_187_4480 pyd genes of Rhizobium sp. strain TAL1145 are required for degradation of 3-hydroxy-4-pyridone, an aromatic intermediate in mimosine metabolism
Inoue_2005_FEMS.Microbiol.Lett_245_145 Diversity of carbazole-degrading bacteria having the car gene cluster: isolation of a novel gram-positive carbazole-degrading bacterium
Thiel_2005_Arch.Microbiol_183_80 Two unusual chlorocatechol catabolic gene clusters in Sphingomonas sp. TFD44
Edvardsen_2005_Curr.Biol_15_R12 Remodelling of the homeobox gene complement in the tunicate Oikopleura dioica
Ferrer_2005_Environ.Microbiol_7_1996 Novel hydrolase diversity retrieved from a metagenome library of bovine rumen microflora
Ferrer_2005_Chem.Biol_12_895 Microbial enzymes mined from the Urania deep-sea hypersaline anoxic basin
Poirel_2005_Antimicrob.Agents.Chemother_49_202 OXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii
Lu_2005_FEMS.Microbiol.Lett_243_149 Molecular cloning and functional analysis of two polyhydroxyalkanoate synthases from two strains of Aeromonas hydrophila spp
Zhang_2005_Acta.Biochim.Biophys.Sin.(Shanghai)_37_613 Expression, purification and crystal structure of a truncated acylpeptide hydrolase from Aeropyrum pernix K1
Wright_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_942 Crystallization and preliminary crystallographic analysis of porcine acylaminoacyl peptidase
Rui_2005_Appl.Environ.Microbiol_71_3995 Protein engineering of epoxide hydrolase from Agrobacterium radiobacter AD1 for enhanced activity and enantioselective production of (R)-1-phenylethane-1,2-diol
Volova_2005_Mikrobiologiia_74_788 [Physiological and biochemical characteristics and capacity for polyhydroxyalkanoates synthesis in a glucose-utilizing strain of hydrogen-oxidizing bacteria, Ralstonia eutropha B8562]
Kobayashi_2005_J.Bacteriol_187_5129 Novel intracellular 3-hydroxybutyrate-oligomer hydrolase in Wautersia eutropha H16
Brayton_2005_Proc.Natl.Acad.Sci.U.S.A_102_844 Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins
Eiglmeier_2005_Insect.Biochem.Mol.Biol_35_799 Comparative analysis of BAC and whole genome shotgun sequences from an Anopheles gambiae region related to Plasmodium encapsulation
Ishida_2005_Proc.Natl.Acad.Sci.U.S.A_102_14075 Rapid inactivation of a moth pheromone
Guo_2005_Acta.Entomol.Sin_48_194 The mutation of carboxylesterase gene of cotton aphid, Aphis gossypii associated with omethoate resistance
Sun_2005_J.Econ.Entomol_98_1325 Polymorphisms in a carboxylesterase gene between organophosphate-resistant and -susceptible Aphis gossypii (Homoptera: Aphididae)
El-Kouhen_2005_FEBS.Lett_579_6067 Identification and characterization of a triacylglycerol lipase in Arabidopsis homologous to mammalian acid lipases
Fraser_2005_Plant.Physiol_138_1136 An expression and bioinformatics analysis of the Arabidopsis serine carboxypeptidase-like gene family
Zhou_2005_J.Biol.Chem_280_35554 Arabidopsis BRS1 is a secreted and active serine carboxypeptidase
Mhaske_2005_Plant.Physiol.Biochem_43_413 Isolation and characterization of an Arabidopsis thaliana knockout line for phospholipid: diacylglycerol transacylase gene (At5g13640)
Feys_2005_Plant.Cell_17_2601 Arabidopsis SENESCENCE-ASSOCIATED GENE101 stabilizes and signals within an ENHANCED DISEASE SUSCEPTIBILITY1 complex in plant innate immunity
Mochizuki_2005_Plant.Cell_17_537 The Arabidopsis WAVY GROWTH 2 protein modulates root bending in response to environmental stimuli
Forsberg_2005_Physiol.Plantarum_123_21 Protease activities in the chloroplast capable of cleaving an LHCII N-terminal peptide
Wiermer_2005_Curr.Opin.Plant.Biol_8_383 Plant immunity: the EDS1 regulatory node
Banas_2005_J.Biol.Chem_280_34626 Cellular sterol ester synthesis in plants is performed by an enzyme (phospholipid:sterol acyltransferase) different from the yeast and mammalian acyl-CoA:sterol acyltransferases
Rabus_2005_Arch.Microbiol_183_27 The genome sequence of an anaerobic aromatic-degrading denitrifying bacterium, strain EbN1
Monod_2005_Microbiology_151_145 Aminopeptidases and dipeptidyl-peptidases secreted by the dermatophyte Trichophyton rubrum
Kaufman_2005_Infect.Immun_73_6584 Markers for host-induced gene expression in Trichophyton dermatophytosis
Sachelaru_2005_J.Bacteriol_187_8516 An alpha\/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans
Frerichs-Deeken_2005_Curr.Microbiol_51_344 Dioxygenases without requirement for cofactors: identification of amino acid residues involved in substrate binding and catalysis, and testing for rate-limiting steps in the reaction of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase
Boer_2005_Yeast_22_523 An extracellular lipase from the dimorphic yeast Arxula adeninivorans: molecular cloning of the ALIP1 gene and characterization of the purified recombinant enzyme
Koseki_2005_Biochim.Biophys.Acta_1722_200 Mutational analysis of a feruloyl esterase from Aspergillus awamori involved in substrate discrimination and pH dependence
Koseki_2005_Biochim.Biophys.Acta_1749_7 Biochemical characterization of recombinant acetyl xylan esterase from Aspergillus awamori expressed in Pichia pastoris: mutational analysis of catalytic residues
Nierman_2005_Nature_438_1151 Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Kotik_2005_J.Biotechnol_120_364 Novel microbial epoxide hydrolases for biohydrolysis of glycidyl derivatives
Bourne_2005_Chem.Biol.Interact_157-158_395 A. niger protein EstA, perhaps a new electrotactin, defines a new class of fungal esterases within the alpha\/beta hydrolase fold superfamily
Basten_2005_Mol.Genet.Genomics_272_673 Characterisation of Aspergillus niger prolyl aminopeptidase
Takahashi_2005_Mol.Microbiol_57_1780 The fungal hydrophobin RolA recruits polyesterase and laterally moves on hydrophobic surfaces
Maeda_2005_Appl.Microbiol.Biotechnol_67_778 Purification and characterization of a biodegradable plastic-degrading enzyme from Aspergillus oryzae
Lee_2005_Bioorg.Med.Chem.Lett_15_471 Synthesis and melanin biosynthesis inhibitory activity of (+\/-)-terrein produced by Penicillium sp. 20135
Schracke_2005_Biochemistry_44_8507 Synthesis of linear gramicidin requires the cooperation of two independent reductases
Ehling-Schulz_2005_Appl.Environ.Microbiol_71_105 Identification and partial characterization of the nonribosomal peptide synthetase gene responsible for cereulide production in emetic Bacillus cereus
Mnisi_2005_Curr.Microbiol_50_196 Cloning and characterization of a carboxylesterase from Bacillus coagulans 81-11
Cerdeno-Tarraga_2005_Science_307_1463 Extensive DNA inversions in the B. fragilis genome control variable gene expression
Nthangeni_2005_J.Microbiol.Methods_61_225 Development of a versatile cassette for directional genome walking using cassette ligation-mediated PCR and its application in the cloning of complete lipolytic genes from Bacillus species
Krastanova_2005_Biochim.Biophys.Acta_1748_222 Heterologous expression, purification, crystallization, X-ray analysis and phasing of the acetyl xylan esterase from Bacillus pumilus
Mukerjee-Dhar_2005_Microbiology_151(Pt 12)_4139 bph genes of the thermophilic PCB degrader, Bacillus sp. JF8: characterization of the divergent ring-hydroxylating dioxygenase and hydrolase genes upstream of the Mn-dependent BphC
Droge_2005_J.Mol.Catal.B.Enzym_32_261 Comparison and functional characterisation of three homologous intracellular carboxylesterases of Bacillus subtilis
Kaneko_2005_Protein.Sci_14_558 Crystal structures of RsbQ, a stress-response regulator in Bacillus subtilis
van den Broek_2005_Appl.Microbiol.Biotechnol_67_641 Cloning and characterization of arabinoxylan arabinofuranohydrolase-D3 (AXHd3) from Bifidobacterium adolescentis DSM20083
Higa-Nishiyama_2005_Transgenic.Res_14_713 A model transgenic cereal plant with detoxification activity for the estrogenic mycotoxin zearalenone
Takahashi-Ando_2005_Appl.Microbiol.Biotechnol_67_838 Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene
Degnan_2005_Genome.Res_15_1023 Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects
Zhang_2005_Insect.Biochem.Mol.Biol_35_153 Molecular and biochemical characterization of juvenile hormone epoxide hydrolase from the silkworm, Bombyx mori
Harhay_2005_BMC.Genomics_6_166 Characterization of 954 bovine full-CDS cDNA sequences
Halling_2005_J.Bacteriol_187_2715 Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis
Chain_2005_Infect.Immun_73_8353 Whole-genome analyses of speciation events in pathogenic Brucellae
Mandrich_2005_J.Mol.Biol_345_501 Role of the N terminus in enzyme activity, stability and specificity in thermophilic esterases belonging to the HSL family
Mezzetti_2005_Chem.Biol_12_427 Mirror-image packing in enantiomer discrimination molecular basis for the enantioselectivity of B.cepacia lipase toward 2-methyl-3-phenyl-1-propanol
Nair_2005_FEMS.Microbiol.Lett_245_337 Conservation of a novel protein associated with an antibiotic efflux operon in Burkholderia cenocepacia
Pauwels_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_791 Crystallization and crystal manipulation of a steric chaperone in complex with its lipase substrate
Kim_2005_BMC.Genomics_6_174 Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies
Inglis_2005_Rev.Soc.Bras.Med.Trop_38_112 PCR methods for laboratory diagnosis of melioidosis.
Porter_2005_J.Neurosci.Res_79_836 Identification and characterization of Caenorhabditis elegans palmitoyl protein thioesterase1
Fouts_2005_PLoS.Biol_3_e15 Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species
Poly_2005_J.Clin.Microbiol_43_2330 Genomic diversity in Campylobacter jejuni: identification of C. jejuni 81-176-specific genes
Chibana_2005_Genetics_170_1525 Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome
Roustan_2005_Appl.Microbiol.Biotechnol_68_203 A novel lipase\/acyltransferase from the yeast Candida albicans: expression and characterisation of the recombinant enzyme
Cao_2005_Shi.Yan.Sheng.Wu.Xue.Bao_38_119 [Cloning and functional study of CaPPe1 in Candida albicans by using Saccharomyses cerevisiae model system]
De Diego_2005_Biomacromolecules_6_1457 Understanding structure-stability relationships of Candida antartica lipase B in ionic liquids
Lavandera_2005_Chembiochem_6_1381 An inverse substrate orientation for the regioselective acylation of 3',5'-diaminonucleosides catalyzed by Candida antarctica lipase B?
Magnusson_2005_Chembiochem_6_1051 Creating space for large secondary alcohols by rational redesign of Candida antarctica lipase B
Qian_2005_J.Am.Chem.Soc_127_13466 Improving the catalytic activity of Candida antarctica lipase B by circular permutation
Ceccorulli_2005_Biomacromolecules_6_902 Cocrystallization of random copolymers of omega-pentadecalactone and epsilon-caprolactone synthesized by lipase catalysis
Schmidt_2005_J.Org.Chem_70_3737 Enzymatic removal of carboxyl protecting groups. 1. Cleavage of the tert-butyl moiety
Lindblad-Toh_2005_Nature_438_803 Genome sequence, comparative analysis and haplotype structure of the domestic dog
Kabir_2005_Am.J.Physiol.Endocrinol.Metab_288_E454 Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance
Ko_2005_Plant.Mol.Biol_58_529 A Colletotrichum gloeosporioides-induced esterase gene of nonclimacteric pepper (Capsicum annuum) fruit during ripening plays a role in resistance against fungal infection
Wu_2005_PLoS.Genet_1_e65 Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901
Lemenager_2005_J.Exp.Bot_56_1221 Purification, molecular cloning, and cell-specific gene expression of the alkaloid-accumulation associated protein CrPS in Catharanthus roseus
Caldwell_2005_Genome.Biol_6_R6 Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis
Thomson_2005_Genome.Res_15_629 The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation
Carlson_2005_Infect.Immun_73_6407 Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains
Tarbouriech_2005_Acta.Crystallogr.D.Biol.Crystallogr_61_194 Molecular determinants of substrate specificity in the feruloyl esterase module of xylanase 10B from Clostridium thermocellum
Methe_2005_Proc.Natl.Acad.Sci.U.S.A_102_10913 The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses
Horinouchi_2005_Appl.Environ.Microbiol_71_5275 Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441
Inui_2005_Appl.Environ.Microbiol_71_407 Isolation and characterization of a native composite transposon, Tn14751, carrying 17.4 kilobases of Corynebacterium glutamicum chromosomal DNA
Suzuki_2005_Appl.Environ.Microbiol_71_3369 Large-scale engineering of the Corynebacterium glutamicum genome
Tauch_2005_J.Bacteriol_187_4671 Complete genome sequence and analysis of the multiresistant nosocomial pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the human skin flora
Likos_2005_J.Gen.Virol_86_2661 A tale of two clades: monkeypox viruses
Morikawa_2005_J.Virol_79_11873 An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection
Loftus_2005_Science_307_1321 The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans
Biondo_2005_Infect.Immun_73_7348 Characterization of two novel cryptococcal mannoproteins recognized by immune sera
Masaki_2005_Appl.Environ.Microbiol_71_7548 Cutinase-like enzyme from the yeast Cryptococcus sp. strain S-2 hydrolyzes polylactic acid and other biodegradable plastics
Prpic_2005_Naturwiss_92_246 A homolog of the hydrolase Notum is expressed during segmentation and appendage formation in the Central American hunting spider Cupiennius salei
Allebrandt_2005_Chem.Biol.Interact_157-158_353 Expression of acetylcholinesterase (AChE) and aryl acylamidase (AAA) during early zebrafish embryogenesis
Zobov_2005_Bull.Exp.Biol.Med_139_68 Delayed effects of daphnia intoxication with selective and nonselective inhibitors of acetylcholinesterase
Seshadri_2005_Science_307_105 Genome sequence of the PCE-dechlorinating bacterium Dehalococcoides ethenogenes
Kube_2005_Nat.Biotechnol_23_1269 Genome sequence of the chlorinated compound-respiring bacterium Dehalococcoides species strain CBDB1
Eichinger_2005_Nature_435_43 The genome of the social amoeba Dictyostelium discoideum
Brock_2005_Development_132_4553 A secreted factor represses cell proliferation in Dictyostelium
Bartolome_2005_Genetics_169_1495 Patterns of selection on synonymous and nonsynonymous variants in Drosophila miranda
Richards_2005_Genome.Res_15_1 Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution
Quesneville_2005_PLoS.Comput.Biol_1_166 Combined evidence annotation of transposable elements in genome sequences
Mueller_2005_Genetics_171_131 Cross-species comparison of Drosophila male accessory gland protein genes
Heidari_2005_Insect.Biochem.Mol.Biol_35_597 Hydrolysis of pyrethroids by carboxylesterases from Lucilia cuprina and Drosophila melanogaster with active sites modified by in vitro mutagenesis
Llopart_2005_Genetics_171_197 Multilocus analysis of introgression between two sympatric sister species of Drosophila: Drosophila yakuba and D. santomea
Lin_2005_J.Am.Chem.Soc_127_11075 In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes
Li_2005_J.Mol.Biol_346_241 Catalytic mechanism of C-C hydrolase MhpC from Escherichia coli: kinetic analysis of His263 and Ser110 site-directed mutants
Dunn_2005_J.Mol.Biol_346_253 The structure of the C-C bond hydrolase MhpC provides insights into its catalytic mechanism
Bischoff_2005_FEMS.Microbiol.Lett_243_285 The chloramphenicol resistance gene cmlA is disseminated on transferable plasmids that confer multiple-drug resistance in swine Escherichia coli
Kuznetsova_2005_FEMS.Microbiol.Rev_29_263 Enzyme genomics: Application of general enzymatic screens to discover new enzymes
Yang_2005_Nucleic.Acids.Res_33_6445 Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery
Collins_2005_Proc.Natl.Acad.Sci.U.S.A_102_838 The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number
Loftus_2005_Nature_433_865 The genome of the protist parasite Entamoeba histolytica
Teng_2005_J.Infect.Dis_191_472 Importance of gls24 in virulence and stress response of Enterococcus faecalis and use of the Gls24 protein as a possible immunotherapy target
Larsson_2005_Nat.Genet_37_153 The complete genome sequence of Francisella tularensis, the causative agent of tularemia
Kruithof_2005_Chemistry_11_6869 Lipase active-site-directed anchoring of organometallics: metallopincer\/protein hybrids
Choi_2005_FEBS.Lett_579_3461 Zinc in lipase L1 from Geobacillus stearothermophilus L1 and structural implications on thermal stability
Li_2005_Protein.Expr.Purif_42_153 Characterization of thermostable lipase from thermophilic Geobacillus sp. TW1
Kim_2005_Mol.Microbiol_58_1102 Two different polyketide synthase genes are required for synthesis of zearalenone in Gibberella zeae
Voigt_2005_Plant.J_42_364 A secreted lipase of Fusarium graminearum is a virulence factor required for infection of cereals
Maier_2005_FEMS.Yeast.Res_5_653 Development of a highly efficient gene targeting system for Fusarium graminearum using the disruption of a polyketide synthase gene as a visible marker
Malz_2005_Fungal.Genet.Biol_42_420 Identification of a gene cluster responsible for the biosynthesis of aurofusarin in the Fusarium graminearum species complex
Kim_2005_Appl.Environ.Microbiol_71_1701 Putative polyketide synthase and laccase genes for biosynthesis of aurofusarin in Gibberella zeae
Gaffoor_2005_Eukaryot.Cell_4_1926 Functional analysis of the polyketide synthase genes in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum)
Prust_2005_Nat.Biotechnol_23_195 Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans
Akashi_2005_Plant.Physiol_137_882 Molecular and biochemical characterization of 2-hydroxyisoflavanone dehydratase. Involvement of carboxylesterase-like proteins in leguminous isoflavone biosynthesis
Harrison_2005_J.Bacteriol_187_4627 Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20
Mirza_2005_Biochemistry_44_15768 Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of alpha\/beta-hydrolases
Jeong_2005_Nucleic.Acids.Res_33_7066 Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent
Hillier_2005_Nature_434_724 Generation and annotation of the DNA sequences of human chromosomes 2 and 4
Miyata_2005_Biochem.Biophys.Res.Commun_329_296 Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha\/beta hydrolase domain containing 2 gene
Gridley_2005_Cell.Signal_17_59 Novel insulin-elicited phosphoproteins in adipocytes
Mikkelsen_2005_Nature_437_69 Initial sequence of the chimpanzee genome and comparison with the human genome
Quistad_2005_Toxicol.Sci_86_291 Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants
Nachon_2005_Biochemistry_44_1154 Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging
Sbarra_2005_Biochim.Biophys.Acta_1736_67 In vitro polyphenol effects on activity, expression and secretion of pancreatic bile salt-dependent lipase
Rebai_2005_Arterioscler.Thromb.Vasc.Biol_25_359 In vitro angiogenic effects of pancreatic bile salt-dependent lipase
Fujikawa_2005_Hum.Exp.Toxicol_24_333 Extremely sensitive biomarker of acute organophosphorus insecticide exposure
Fleming_2005_J.Mol.Biol_352_165 Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil
Geshi_2005_Hypertens.Res_28_719 A single nucleotide polymorphism in the carboxylesterase gene is associated with the responsiveness to imidapril medication and the promoter activity
Quinney_2005_J.Pharmacol.Exp.Ther_313_1011 Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide
Kim_2005_J.Med.Chem_48_141 (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)- yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Weihofen_2005_J.Biol.Chem_280_14911 Crystal structures of HIV-1 Tat-derived nonapeptides Tat-(1-9) and Trp2-Tat-(1-9) bound to the active site of dipeptidyl-peptidase IV (CD26)
Radicke_2005_J.Physiol_565_751 Expression and function of dipeptidyl-aminopeptidase-like protein 6 as a putative beta-subunit of human cardiac transient outward current encoded by Kv4.3
Maes_2005_Biochem.J_386_315 Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)\/dipeptidyl peptidase 7 (DPP7)
Jiaang_2005_Bioorg.Med.Chem.Lett_15_687 Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8
Schmelzer_2005_Proc.Natl.Acad.Sci.U.S.A_102_9772 Soluble epoxide hydrolase is a therapeutic target for acute inflammation
Aertgeerts_2005_J.Biol.Chem_280_19441 Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha
Zschenker_2005_J.Biochem_137_387 Systematic mutagenesis of potential glycosylation sites of lysosomal acid lipase
Ben Ali_2005_J.Lipid.Res_46_994 Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases
Petry_2005_J.Lipid.Res_46_603 Sensitive assay for hormone-sensitive lipase using NBD-labeled monoacylglycerol to detect low activities in rat adipocytes
Claus_2005_J.Pharmacol.Exp.Ther_315_1396 Specific inhibition of hormone-sensitive lipase improves lipid profile while reducing plasma glucose
Nusbaum_2005_Nature_437_551 DNA sequence and analysis of human chromosome 18
Gauster_2005_J.Lipid.Res_46_1517 Endothelial lipase releases saturated and unsaturated fatty acids of high density lipoprotein phosphatidylcholine
Nomura_2005_Proc.Natl.Acad.Sci.U.S.A_102_6195 A brain detoxifying enzyme for organophosphorus nerve poisons
Nam_2005_Proc.Natl.Acad.Sci.U.S.A_102_6137 Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter
Ross_2005_Nature_434_325 The DNA sequence of the human X chromosome
Ylisaukko-oja_2005_Eur.J.Hum.Genet_13_1285 Analysis of four neuroligin genes as candidates for autism
Shariat-Madar_2005_Am.J.Physiol.Heart.Circ.Physiol_289_H2697 Overexpression of prolylcarboxypeptidase enhances plasma prekallikrein activation on Chinese hamster ovary cells
Szeltner_2005_Cell.Mol.Life.Sci_62_2376 The PREPL A protein, a new member of the prolyl oligopeptidase family, lacking catalytic activity
Parvari_2005_Genomics_86_195 The 2p21 deletion syndrome: characterization of the transcription content
Luther_2005_Genes.Immun_6_1 Alternatively spliced transcripts of the thymus-specific protease PRSS16 are differentially expressed in human thymus
Cheunsuk_2005_Mol.Cell.Biol_25_789 Prss16 is not required for T-cell development
Mogensen_2005_Biochemistry_44_1719 Activation, inhibition, and destabilization of Thermomyces lanuginosus lipase by detergents
Hedin_2005_Biochemistry_44_16658 Implications of surface charge and curvature for the binding orientation of Thermomyces lanuginosus lipase on negatively charged or zwitterionic phospholipid vesicles as studied by ESR spectroscopy
Altermann_2005_Proc.Natl.Acad.Sci.U.S.A_102_3906 Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM
Bath_2005_FEMS.Microbiol.Lett_253_75 The cell surface of Lactobacillus reuteri ATCC 55730 highlighted by identification of 126 extracellular proteins from the genome sequence
Holland_2005_Int.Dairy.J_15_711 Esterases of lactic acid bacteria and cheese flavour: Milk fat hydrolysis, alcoholysis and esterification.
Chaillou_2005_Nat.Biotechnol_23_1527 The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K
Ivens_2005_Science_309_436 The genome of the kinetoplastid parasite, Leishmania major
Newcomb_2005_J.Mol.Evol_60_207 Multiple mutations and gene duplications conferring organophosphorus insecticide resistance have been selected at the Rop-1 locus of the sheep blowfly, Lucilia cuprina
Hu_2005_Plant.J_42_376 EDS1 in tomato is required for resistance mediated by TIR-class R genes and the receptor-like R gene Ve
Osada_2005_Mol.Biol.Evol_22_1976 Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs
Dean_2005_Nature_434_980 The genome sequence of the rice blast fungus Magnaporthe grisea
Matsunaga_2005_DNA.Res_12_157 Complete genome sequence of the facultative anaerobic magnetotactic bacterium Magnetospirillum sp. strain AMB-1
Kamil_2005_J.Virol_79_6984 vLIP, a viral lipase homologue, is a virulence factor of Marek's disease virus
Lian_2005_Am.J.Pathol_167_813 Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice
Carninci_2005_Science_309_1559 The transcriptional landscape of the mammalian genome
Linke_2005_J.Biol.Chem_280_23287 Isolation and characterization of a microsomal acid retinyl ester hydrolase
Park_2005_Am.J.Physiol.Endocrinol.Metab_289_E30 Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscle and heart
Fortier_2005_J.Lipid.Res_46_1860 Human hormone-sensitive lipase (HSL): expression in white fat corrects the white adipose phenotype of HSL-deficient mice
Katayama_2005_Science_309_1564 Antisense transcription in the mammalian transcriptome
Croteau_2005_Mamm.Genome_16_127 Increased plasticity of genomic imprinting of Dlk1 in brain is due to genetic and epigenetic factors
Florea_2005_Genome.Res_15_54 Gene and alternative splicing annotation with AIR
Griffey_2005_Mol.Ther_12_413 AAV2-mediated ocular gene therapy for infantile neuronal ceroid lipofuscinosis
Jalanko_2005_Neurobiol.Dis_18_226 Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons
Virmani_2005_Neurobiol.Dis_20_314 Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice
Schimenti_2005_Proc.Natl.Acad.Sci.U.S.A_102_3342 Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion
Vasconcelos_2005_J.Bacteriol_187_5568 Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae
Li_2005_Proc.Natl.Acad.Sci.U.S.A_102_12344 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis
Miltner_2005_Infect.Immun_73_4214 Identification of Mycobacterium avium genes that affect invasion of the intestinal epithelium
Sonden_2005_Mol.Microbiol_58_426 Gap, a mycobacterial specific integral membrane protein, is required for glycolipid transport to the cell surface
Jesenska_2005_Appl.Environ.Microbiol_71_6736 Cloning, biochemical properties, and distribution of mycobacterial haloalkane dehalogenases
Zhang_2005_Protein.Expr.Purif_42_59 Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis
Waddell_2005_Lett.Appl.Microbiol_40_201 Inactivation of polyketide synthase and related genes results in the loss of complex lipids in Mycobacterium tuberculosis H37Rv
Shan_2005_Proc.Natl.Acad.Sci.U.S.A_102_3599 Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity
Rasmussen_2005_Mol.Microbiol_56_1358 Coupling of multicellular morphogenesis and cellular differentiation by an unusual hybrid histidine protein kinase in Myxococcus xanthus
Falb_2005_Genome.Res_15_1336 Living with two extremes: conclusions from the genome sequence of Natronomonas pharaonis
Forouhar_2005_Proc.Natl.Acad.Sci.U.S.A_102_1773 Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
Schulze_2005_Anal.Chem_77_5823 Insecticide detection through protein engineering of Nippostrongylus brasiliensis acetylcholinesterase B
Wright_2005_J.Biol.Chem_280_40271 UV irradiation and desiccation modulate the three-dimensional extracellular matrix of Nostoc commune (Cyanobacteria)
Matsumoto_2005_Nature_436_793 The map-based sequence of the rice genome.
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Buell_2005_Genome.Res_15_1284 Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species
Ueguchi-Tanaka_2005_Nature_437_693 GIBBERELLIN INSENSITIVE DWARF1 encodes a soluble receptor for gibberellin
Cheng_2005_Mol.Genet.Genomics_274_337 A fine physical map of the rice chromosome 5
Messing_2005_BMC.Biol_3_20 The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications
Stover_2005_Mol.Biol.Evol_22_1539 Reciprocal fusions of two genes in the formaldehyde detoxification pathway in ciliates and diatoms
Giovannoni_2005_Science_309_1242 Genome streamlining in a cosmopolitan oceanic bacterium
Ast_2005_Environ.Microbiol_7_1641 Phylogenetic resolution and habitat specificity of members of the Photobacterium phosphoreum species group
Vezzi_2005_Science_307_1459 Life at depth: Photobacterium profundum genome sequence and expression analysis
Thor_2005_FEMS.Yeast.Res_5_935 Cloning and characterization of the Pichia pastoris MET2 gene as a selectable marker
Hall_2005_Science_307_82 A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses
Baek_2005_Pestic.Biochem.Physiol_81_164 Identification and characterization of ace1-type acetylcholinesterase likely associated with organophosphate resistance in Plutella xylostella
Nakajima_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_1046 Crystallization and preliminary X-ray characterization of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis
Joardar_2005_J.Bacteriol_187_6488 Whole-genome sequence analysis of Pseudomonas syringae pv. phaseolicola 1448A reveals divergence among pathovars in genes involved in virulence and transposition
Fujii_2005_Protein.Eng.Des.Sel_18_93 Directed evolution of Pseudomonas aeruginosa lipase for improved amide-hydrolyzing activity
Reetz_2005_Angew.Chem.Int.Ed.Engl_44_4192 Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test
Pesaresi_2005_Curr.Microbiol_50_102 Isolation, characterization, and heterologous expression of a carboxylesterase of Pseudomonas aeruginosa PAO1
Pesaresi_2005_Biochim.Biophys.Acta_1752_197 Crystallization, X-ray diffraction analysis and phasing of carboxylesterase PA3859 from Pseudomonas aeruginosa
Smith_2005_J.Bacteriol_187_2138 Evidence for diversifying selection at the pyoverdine locus of Pseudomonas aeruginosa
Paulsen_2005_Nat.Biotechnol_23_873 Complete genome sequence of the plant commensal Pseudomonas fluorescens Pf-5
Fushinobu_2005_Biosci.Biotechnol.Biochem_69_491 A series of crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with various cleavage products
Jiang_2005_Mol.Biotechnol_31_95 Cloning and expression of a novel lipase gene from Pseudomonas fluorescens B52
Medigue_2005_Genome.Res_15_1325 Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125
Kapetaniou_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_479 Crystallization and preliminary X-ray analysis of a novel thermoalkalophilic poly(3-hydroxybutyrate) depolymerase (PhaZ7) from Paucimonas lemoignei
Solaiman_2005_Curr.Microbiol_50_329 Genetic characterization of the poly(hydroxyalkanoate) synthases of various Pseudomonas oleovorans strains
Endo_2005_J.Bacteriol_187_847 Identification and characterization of genes involved in the downstream degradation pathway of gamma-hexachlorocyclohexane in Sphingomonas paucimobilis UT26
Abe_2005_J.Bacteriol_187_2030 A tetrahydrofolate-dependent O-demethylase, LigM, is crucial for catabolism of vanillate and syringate in Sphingomonas paucimobilis SYK-6
Elmi_2005_J.Bacteriol_187_8470 Stereoselective esterase from Pseudomonas putida IFO12996 reveals alpha\/beta hydrolase folds for D-beta-acetylthioisobutyric acid synthesis
Kim_2005_Acta.Crystallogr.D.Biol.Crystallogr_61_920 Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase
Feil_2005_Proc.Natl.Acad.Sci.U.S.A_102_11064 Comparison of the complete genome sequences of Pseudomonas syringae pv. syringae B728a and pv. tomato DC3000
Grogan_2005_Biochem.J_388_721 Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage
Klomklang_2005_Microbiology_151_1255 Biochemical and molecular characterization of a periplasmic hydrolase for oxidized polyvinyl alcohol from Sphingomonas sp. strain 113P3
Shintani_2005_Appl.Microbiol.Biotechnol_67_370 Large plasmid pCAR2 and class II transposon Tn4676 are functional mobile genetic elements to distribute the carbazole\/dioxin-degradative car gene cluster in different bacteria
Shintani_2005_Biotechnol.Lett_27_1847 Recipient range of IncP-7 conjugative plasmid pCAR2 from Pseudomonas putida HS01 is broader than from other Pseudomonas strains
Fukui_2005_Genome.Res_15_352 Complete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomes
Jung_2005_Mol.Pharmacol_68_1196 Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors
Rendina_2005_Biochem.J_388_895 Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates
Najjar_2005_Cell.Metab_2_43 Insulin acutely decreases hepatic fatty acid synthase activity
Takahashi_2005_Int.J.Neuropsychopharmacol_8_381 Expression of Ndrg2 in the rat frontal cortex after antidepressant and electroconvulsive treatment
Takahashi_2005_Neurosci.Lett_388_157 Ndrg2 promotes neurite outgrowth of NGF-differentiated PC12 cells
Furihata_2005_Biochem.Pharmacol_69_1287 Dexamethasone-induced methylprednisolone hemisuccinate hydrolase: its identification as a member of the rat carboxylesterase 2 family and its unique existence in plasma
Shimokawa_2005_Cardiovasc.Res_66_594 Increased expression of endothelial lipase in rat models of hypertension
Zagha_2005_J.Biol.Chem_280_18853 DPP10 modulates Kv4-mediated A-type potassium channels
Sayari_2005_FEBS.Lett_579_976 N-terminal peptide of Rhizopus oryzae lipase is important for its catalytic properties
Shiraga_2005_Appl.Microbiol.Biotechnol_68_779 Creation of Rhizopus oryzae lipase having a unique oxyanion hole by combinatorial mutagenesis in the lid domain
Di Lorenzo_2005_Appl.Environ.Microbiol_71_8974 Heterologous production of functional forms of Rhizopus oryzae lipase in Escherichia coli
Simser_2005_Mol.Microbiol_58_71 A novel and naturally occurring transposon, ISRpe1 in the Rickettsia peacockii genome disrupting the rickA gene involved in actin-based motility
Ogata_2005_PLoS.Biol_3_E248 The genome sequence of Rickettsia felis identifies the first putative conjugative plasmid in an obligate intracellular parasite
Chiu_2005_Nucleic.Acids.Res_33_1690 The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen
Ahmed_2005_J.Antimicrob.Chemother_55_371 Molecular characterization of integrons in non-typhoid Salmonella serovars isolated in Japan: description of an unusual class 2 integron
Mongodin_2005_Proc.Natl.Acad.Sci.U.S.A_102_18147 The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea
Bentley_2005_Mol.Biochem.Parasitol_141_119 Expression and comparative functional characterisation of recombinant acetylcholinesterase from three species of Schistosoma
Martin-Castellanos_2005_Curr.Biol_15_2056 A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events
Ecroyd_2005_Biochem.J_392_211 The epididymal soluble prion protein forms a high-molecular-mass complex in association with hydrophobic proteins
Partridge_2005_J.Clin.Microbiol_43_4298 Correctly identifying the streptothricin resistance gene cassette
Fridman_2005_Plant.Cell_17_1252 Metabolic, genomic, and biochemical analyses of glandular trichomes from the wild tomato species Lycopersicon hirsutum identify a key enzyme in the biosynthesis of methylketones
Hoffman_2005_J.Allergy.Clin.Immunol_115_611 Sol i 1, the phospholipase allergen of imported fire ant venom
Elfstrom_2005_Biochem.J_390_633 Catalysis of potato epoxide hydrolase, StEH1
Pajerowska_2005_Mol.Plant.Microbe.Interact_18_1107 Potato homologs of Arabidopsis thaliana genes functional in defense signaling--identification, genetic mapping, and molecular cloning
Carvalho_2005_Gene_359_91 The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation
Kopp_2005_ChemBioChem_6_1277 Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes
Mayrhofer_2005_Eukaryot.Cell_4_661 Functional characterization of an alpha-factor-like Sordaria macrospora peptide pheromone and analysis of its interaction with its cognate receptor in Saccharomyces cerevisiae
Graham_2005_Plant.Physiol_139_1784 The diphenylether herbicide lactofen induces cell death and expression of defense-related genes in soybean
Saera-Vila_2005_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_142_224 Molecular characterization of gilthead sea bream (Sparus aurata) lipoprotein lipase. Transcriptional regulation by season and nutritional condition in skeletal muscle and fat storage tissues
Kmunicek_2005_Biochemistry_44_3390 Quantitative analysis of substrate specificity of haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26
Gill_2005_J.Bacteriol_187_2426 Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain
Takeuchi_2005_J.Bacteriol_187_7292 Whole-genome sequencing of staphylococcus haemolyticus uncovers the extreme plasticity of its genome and the evolution of human-colonizing staphylococcal species
Kuroda_2005_Proc.Natl.Acad.Sci.U.S.A_102_13272 Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection
Tettelin_2005_Proc.Natl.Acad.Sci.U.S.A_102_13950 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial pan-genome
Liu_2005_Chem.Biol_12_293 The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases
Miao_2005_Microbiology_151_1507 Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry
Green_2005_J.Infect.Dis_192_760 Genome sequence of a serotype M28 strain of group a streptococcus: potential new insights into puerperal sepsis and bacterial disease specificity
Sumby_2005_J.Infect.Dis_192_771 Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events
Jobin_2005_J.Bacteriol_187_795 Cloning, purification, and enzymatic properties of dipeptidyl peptidase IV from the swine pathogen Streptococcus suis
Blodgett_2005_Antimicrob.Agents.Chemother_49_230 Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736
Chen_2005_J.Bacteriol_187_4992 The genome of Sulfolobus acidocaldarius, a model organism of the Crenarchaeota
Aiki_2005_Pestic.Biochem.Physiol_82_154 Amino acid substitution in Ace paralogous acetylcholinesterase accompanied by organophosphate resistance in the spider mite Tetranychus kanzawai
Goettig_2005_J.Biol.Chem_280_33387 X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum
Pain_2005_Science_309_131 Genome of the host-cell transforming parasite Theileria annulata compared with T. parva
Muller_2005_Macromol.Rapid.Commun_26_1400 Enzymatic degradation of poly(ethylene terephthalate):rapid hydrolyse using a hydrolase from T.fusca
Kleeberg_2005_Biomacromolecules_6_262 Characterization of a new extracellular hydrolase from Thermobifida fusca degrading aliphatic-aromatic copolyesters
Gardner_2005_Science_309_134 Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes
Murayama_2005_Proteins_58_982 Crystal structure of TT1662 from Thermus thermophilus HB8: a member of the alpha\/beta hydrolase fold enzymes
Rowland_2005_Plant.Cell_17_295 Functional analysis of Avr9\/Cf-9 rapidly elicited genes identifies a protein kinase, ACIK1, that is essential for full Cf-9-dependent disease resistance in tomato
Harel_2005_Chem.Biol.Interact_157-158_153 The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase
Harel_2005_Mol.Pharmacol_67_1874 The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action
Haviv_2005_J.Am.Chem.Soc_127_11029 Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase
El-Sayed_2005_Science_309_409 The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
Berriman_2005_Science_309_416 The genome of the African trypanosome Trypanosoma brucei
El-Sayed_2005_Science_309_404 Comparative genomics of trypanosomatid parasitic protozoa
Morty_2005_J.Biol.Chem_280_10925 Oligopeptidase B from Trypanosoma evansi. A parasite peptidase that inactivates atrial natriuretic factor in the bloodstream of infected hosts
Oz_2005_Appl.Environ.Microbiol_71_344 Roseobacter-like bacteria in red and mediterranean sea aerobic anoxygenic photosynthetic populations
Pantou_2005_FEMS.Microbiol.Lett_245_213 Electrophoretic karyotype and gene mapping of the vascular wilt fungus Verticillium dahliae
Alice_2005_J.Bacteriol_187_2209 Plasmid- and chromosome-encoded redundant and specific functions are involved in biosynthesis of the siderophore anguibactin in Vibrio anguillarum 775: a case of chance and necessity?
Ruby_2005_Proc.Natl.Acad.Sci.U.S.A_102_3004 Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with pathogenic congeners
Salzberg_2005_Genome.Biol_6_R23 Serendipitous discovery of Wolbachia genomes in multiple Drosophila species
Foster_2005_PLoS.Biol_3_e121 The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode
Thieme_2005_J.Bacteriol_187_7254 Insights into genome plasticity and pathogenicity of the plant pathogenic bacterium Xanthomonas campestris pv. vesicatoria revealed by the complete genome sequence
Qian_2005_Genome.Res_15_757 Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris
Lee_2005_Nucleic.Acids.Res_33_577 The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the bacterial blight pathogen of rice
Ochiai_2005_Jpn.Agric.Res.Q_39_275 Genome sequence of Xanthomonas oryzae pv. oryzae suggests contribution of large numbers of effector genes and insertion sequences to its race diversity
Yang_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_703 Cloning purification crystallisation and prliminary X-ray characterisation of a conserved hypothetical protein XC6422 from Xanthomonas campestris
Fickers_2005_Fungal.Genet.Biol_42_264 Identification and characterisation of LIP7 and LIP8 genes encoding two extracellular triacylglycerol lipases in the yeast Yarrowia lipolytica
Mima_2005_J.Mol.Biol_346_1323 Structure of the carboxypeptidase Y inhibitor IC in complex with the cognate proteinase reveals a novel mode of the proteinase-protein inhibitor interaction
Quevillon-Cheruel_2005_Protein.Sci_14_1350 Crystal structure of yeast YHR049W\/FSH1, a member of the serine hydrolase family
Zaim_2005_J.Biol.Chem_280_28 Identification of new genes regulated by the Crt1 transcription factor, an effector of the DNA damage checkpoint pathway in Saccharomyces cerevisiae
Nguyen_2005_FEMS.Yeast.Res_5_471 Evolutionary relationships between the former species Saccharomyces uvarum and the hybrids Saccharomyces bayanus and Saccharomyces pastorianus\; reinstatement of Saccharomyces uvarum (Beijerinck) as a distinct species
Van Hoof_2005_Biochem.J_386_93 Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2
Elfstrom_2005_Biochim.Biophys.Acta_1748_213 The Saccharomyces cerevisiae ORF YNR064c protein has characteristics of an 'orphaned' epoxide hydrolase
Jandrositz_2005_Biochim.Biophys.Acta_1735_50 The lipid droplet enzyme Tgl1p hydrolyzes both steryl esters and triglycerides in the yeast, Saccharomyces cerevisiae
Gruhler_2005_Mol.Cell.Proteomics_4_310 Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway
Arndt_2005_Proteins_58_755 Crystal structure of an alpha\/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution
Seo_2005_Nat.Biotechnol_23_63 The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4
Wang_2005_Theor.Appl.Genet_112_72 Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments
Kim_2005_Chemosphere_60_1349 Biodegradation and detoxification of organophosphate insecticide, malathion by Fusarium oxysporum f. sp. pisi cutinase
Kim_2005_Biotechnol.Lett_27_635 Enzymatic degradation of dibutyl phthalate and toxicity of its degradation products
Kim_2005_Arch.Microbiol_184_25 Biodegradation of dipropyl phthalate and toxicity of its degradation products: a comparison of Fusarium oxysporum f. sp. pisi cutinase and Candida cylindracea esterase
Arkus_2005_Arch.Biochem.Biophys_438_146 Mechanistic analysis of wheat chlorophyllase
Yoon_2005_Int.J.Syst.Evol.Microbiol_55_733 Bacillus cibi sp. nov., isolated from jeotgal, a traditional Korean fermented seafood
Hughes_2005_Nature_437_100 Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee
Gregan_2005_Curr.Biol_15_1663 Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast
Ruswandi_2005_J.Gen.Plant.Pathol_71_107 Structural analysis of cosmid clone pcAFT-2 carrying AFT10-1 encoding an acyl-CoA dehydrogenase involved in AF-toxin production in the strawberry pathotype of Alternaria alternata
Hrabovska_2005_Chem.Biol.Interact_157-158_71 Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse
Boudinot_2005_Pharmacol.Biochem.Behav_80_53 Effects of acetylcholinesterase and butyrylcholinesterase inhibition on breathing in mice adapted or not to reduced acetylcholinesterase
Girard_2005_Chem.Biol.Interact_157-158_87 Synaptic remodeling at the skeletal neuromuscular junction of acetylcholinesterase knockout mice and its physiological relevance
Camp_2005_Chem.Biol.Interact_157-158_79 Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion
De Jaco_2005_Chem.Biol.Interact_157-158_372 Influence of the 5' intron in the control of acetylcholinesterase gene expression during myogenesis
Shafferman_2005_Chem.Biol.Interact_157-158_123 Functional requirements for the optimal catalytic configuration of the AChE active center
On-Kei Chan_2005_Clin.Chim.Acta_351_155 Novel mutations in the BCHE gene in patients with no butyrylcholinesterase activity
Levano_2005_Anesthesiology_102_531 Genotyping the butyrylcholinesterase in patients with prolonged neuromuscular block after succinylcholine
de Souza_2005_Mol.Genet.Metab_84_349 Four new mutations in the BCHE gene of human butyrylcholinesterase in a Brazilian blood donor sample
Barak_2005_Chem.Biol.Interact_157-158_219 Lessons from functional analysis of AChE covalent and noncovalent inhibitors for design of AD therapeutic agents
Cassanelli_2005_Pest.Manag.Sci_61_91 Use of the RFLP-PCR diagnostic test for characterizing MACE and kdr insecticide resistance in the peach potato aphid Myzus persicae
Gao_2005_Mol.Pharmacol_67_204 Gene transfer of cocaine hydrolase suppresses cardiovascular responses to cocaine in rats
Gao_2005_Chem.Biol.Interact_157-158_97 Visualizing viral transduction of a cocaine-hydrolyzing, human butyrylcholinesterase in rats
Hamza_2005_J.Phys.Chem.B_109_4776 Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants
Pan_2005_Proc.Natl.Acad.Sci.U.S.A_102_16656 Computational redesign of human butyrylcholinesterase for anticocaine medication
De Jaco_2005_Chem.Biol.Interact_157-158_371 A single mutation near the C-terminus in alpha\/beta hydrolase fold protein family causes a defect in protein processing
Ordentlich_2005_Chem.Biol.Interact_157-158_191 The role of AChE active site gorge in determining stereoselectivity of charged and noncharged VX enantiomers
Hawkes_2005_Pestic.Biochem.Physiol_81_154 Detection of resistance-associated point mutations of organophosphate-insensitive acetylcholinesterase in the olive fruit fly, Bactrocera oleae (Gmelin)
Abe_2005_Bioorg.Med.Chem_13_785 Synthesis and biological activity of sulphostin analogues, novel dipeptidyl peptidase IV inhibitors
Abe_2005_J.Antibiot.(Tokyo)_58_111 Sulphostin, a novel inhibitor of dipeptidyl peptidases IV (DPPIV) that stimulates hematopoiesis in mice
Bartling_2005_J.Appl.Toxicol_25_568 Effect of metoclopramide and ranitidine on the inhibition of human AChE by VX in vitro
Petroianu_2005_J.Appl.Toxicol_25_60 Weak inhibitors protect cholinesterases from strong inhibitors (paraoxon): in vitro effect of ranitidine
Petroianu_2005_J.Appl.Toxicol_25_68 Protective agents in acute high-dose organophosphate exposure: comparison of ranitidine with pralidoxime in rats
Kishimoto_2005_Appl.Microbiol.Biotechnol_68_198 Chlorogenate hydrolase-catalyzed synthesis of hydroxycinnamic acid ester derivatives by transesterification, substitution of bromine, and condensation reactions
Belluti_2005_J.Med.Chem_48_4444 Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation
Andrade_2005_Bioorg.Med.Chem_13_4092 Indole alkaloids from Tabernaemontana australis (Muell. Arg) Miers that inhibit acetylcholinesterase enzyme
Solaiman_2005_J.Ind.Microbiol.Biotechnol_32_75 Poly(hydroxyalkanoate) synthase genotype and PHA production of Pseudomonas corrugata and P. mediterranea
Ruel_2005_Arterioscler.Thromb.Vasc.Biol_25_2600 Effect of fenofibrate on plasma lipoprotein composition and kinetics in patients with complete hepatic lipase deficiency
Wheelock_2005_Aquat.Toxicol_74_172 Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos
Borrelli_2005_Eur.J.Pharmacol_521_139 Effect of caffeic acid phenethyl ester on gastric acid secretion in vitro
Alonso_2005_Bioorg.Med.Chem_13_6588 Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE
Parnas_2005_J.Neurophysiol_93_3257 Depolarization initiates phasic acetylcholine release by relief of a tonic block imposed by presynaptic M2 muscarinic receptors
Gulledge_2005_J.Neurosci_25_10308 Cholinergic inhibition of neocortical pyramidal neurons
Yoon_2005_Neuropharmacol_49_275 Intrathecal neostigmine reduces the zymosan-induced inflammatory response in a mouse air pouch model via adrenomedullary activity: involvement of spinal muscarinic type 2 receptors
Lamango_2005_J.Biochem.Mol.Toxicol_19_347 Liver prenylated methylated protein methyl esterase is an organophosphate-sensitive enzyme
Glynn_2005_Biochim.Biophys.Acta_1736_87 Neuropathy target esterase and phospholipid deacylation
Zhang_2005_Biotechnol.Appl.Biochem_42_67 Experimental optimization of enzymic kinetic resolution of racemic flurbiprofen
Decker_2005_Eur.J.Med.Chem_40_305 Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine
Nakajima_2005_Eur.J.Clin.Pharmacol_61_25 Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients
Cappelli_2005_J.Med.Chem_48_3564 Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties
Dickschat_2005_J.Chem.Ecol_31_925 The chafer pheromone buibuilactone and ant pyrazines are also produced by marine bacteria
Graca_2005_Vet.Clin.Pathol_34_39 Validation and diagnostic efficacy of a lipase assay using the substrate 1,2-o-dilauryl-rac-glycero glutaric acid-(6' methyl resorufin)-ester for the diagnosis of acute pancreatitis in dogs
Sheng_2005_Bioorg.Med.Chem.Lett_15_3834 Design, synthesis, and evaluation of 2-phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors
Nagata_2005_Appl.Environ.Microbiol_71_2183 Degradation of beta-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26
Reisenman_2005_J.Neurosci_25_8017 Chemosensory selectivity of output neurons innervating an identified, sexually isomorphic olfactory glomerulus
Shimoda_2005_J.Chem.Ecol_31_2019 The involvement of volatile infochemicals from spider mites and from food-plants in prey location of the generalist predatory mite Neoseiulus californicus
Ito_2005_Arch.Toxicol_79_147 Species differences in the metabolism of di(2-ethylhexyl) phthalate (DEHP) in several organs of mice, rats, and marmosets
Fujisawa_2005_J.Pestic.Sci_30_103 Oxidative Activation and Degradation of Organophosphorus Pesticides Mediated by Iron Porphyrins
Rosini_2005_J.Med.Chem_48_360 Rational approach to discover multipotent anti-Alzheimer drugs
Anspaugh_2005_J.Insect.Physiol_51_523 Regulation of JH epoxide hydrolase versus JH esterase activity in the cabbage looper, Trichoplusia ni, by juvenile hormone and xenobiotics
Hashimoto_2005_J.Urol_174_1137 Effects of the selective acetylcholinesterase inhibitor TAK-802 on the voiding behavior and bladder mass increase in rats with partial bladder outlet obstruction
Ishichi_2005_Bioorg.Med.Chem_13_1901 Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3 ,2,1-ij]quinolin-4-one (TAK-802) and related compounds
Nagabukuro_2005_BJU.Int_95_1071 Effects of TAK-802, a novel acetylcholinesterase inhibitor, and tamsulosin, an alpha1-adrenoceptor antagonist, and their synergistic effects on the urodynamic characteristics in a guinea-pig model of functional bladder outlet obstruction
Nagabukuro_2005_Life.Sci_77_3276 Differential effects of TAK-802, a selective acetylcholinesterase inhibitor, and carbamate acetylcholinesterase inhibitors on contraction of the detrusor smooth muscle of the guinea pig
Jung_2005_Hypertension_45_759 Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension
Viegas_2005_Bioorg.Med.Chem_13_4184 New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids
Viegas_2005_Mini.Rev.Med.Chem_5_915 New anti-Alzheimer drugs from biodiversity: the role of the natural acetylcholinesterase inhibitors
Munoz-Ruiz_2005_J.Med.Chem_48_7223 Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease
Molinari_2005_J.Appl.Microbiol_99_960 Newly isolated Streptomyces spp. as enantioselective biocatalysts: hydrolysis of 1,2-O-isopropylidene glycerol racemic esters
Obregon_2005_Neurochem.Res_30_379 Effects per se of organic solvents in the cerebral acetylcholinesterase of rats
Kucukkilinc_2005_Arch.Biochem.Biophys_440_118 Inhibition of human plasma cholinesterase by malachite green and related triarylmethane dyes: mechanistic implications
Heckmann_2005_Pest.Manag.Sci_61_627 Relationship between biochemical biomarkers and pre-copulatory behaviour and mortality in Gammarus pulex following pulse-exposure to lambda-cyhalothrin
Grimsley_2005_Arch.Biochem.Biophys_442_169 Structural and mutational studies of organophosphorus hydrolase reveal a cryptic and functional allosteric-binding site
Faulds_2005_Febs.J_272_4362 Probing the determinants of substrate specificity of a feruloyl esterase, AnFaeA, from Aspergillus niger
Akiyama_2005_Nature_435_824 Plant sesquiterpenes induce hyphal branching in arbuscular mycorrhizal fungi
Sadler_2005_Development_132_3561 A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease
Ostrowska_2005_J.Cardiovasc.Pharmacol_45_348 Ebelactone B, an inhibitor of extracellular cathepsin A-type enzyme, suppresses platelet aggregation ex vivo in renovascular hypertensive rats
Edens_2005_J.Agric.Food.Chem_53_7950 Extracellular prolyl endoprotease from Aspergillus niger and its use in the debittering of protein hydrolysates
Mavropoulos_2005_J.Rheumatol_32_2116 Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78\/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis
Vertommen_2005_J.Biotechnol_120_376 Enzymatic surface modification of poly(ethylene terephthalate)
Khanna_2005_Biotechnol.Lett_27_1401 Repeated batch cultivation of Ralstonia eutropha for Poly (beta-hydroxybutyrate) production
Saario_2005_Chem.Biol_12_649 Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes
Nazi_2005_Biochemistry_44_13560 Catalytic mechanism of fungal homoserine transacetylase
Augeri_2005_J.Med.Chem_48_5025 Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Brandt_2005_Biochem.Pharmacol_70_134 Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile)
Srinivasan_2005_Indian.J.Exp.Biol_43_241 Effect of losartan and enalapril on cognitive deficit caused by Goldblatt induced hypertension
Kubo_2005_Drug.Metab.Dispos_33_1482 Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2)
Wadkins_2005_J.Med.Chem_48_2906 Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases
Birner-Gruenberger_2005_Mol.Cell.Proteomics_4_1710 The lipolytic proteome of mouse adipose tissue
Augoustides_2005_J.ECT_21_128 Customized anesthetic preservation of ictal threshold in electroconvulsive therapy: role of adjunctive remifentanil with etomidate
Baraka_2005_Middle.East.J.Anaesthesiol_18_477 Does pancuronium or cisatracurium delay the rate of arousal following remifentanil-based anesthesia?
Schmidinger_2005_Chembiochem_6_1776 Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases
Wang_2005_Biomed.Chromatogr_19_454 Effect of alcohols and temperature on the direct chiral resolutions of fipronil, isocarbophos and carfentrazone-ethyl
Schopfer_2005_Anal.Biochem_345_122 Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410)
Schopfer_2005_Chem.Res.Toxicol_18_747 Reaction kinetics of biotinylated organophosphorus toxicant, FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase
Peeples_2005_Toxicol.Sci_83_303 Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry
Furnes_2005_Drug.Metab.Dispos_33_214 Extrahepatic metabolism of carbamate and organophosphate thioether compounds by the flavin-containing monooxygenase and cytochrome P450 systems
Sagi_2005_Br.J.Pharmacol_146_553 The neurochemical and behavioral effects of the novel cholinesterase-monoamine oxidase inhibitor, ladostigil, in response to L-dopa and L-tryptophan, in rats
Youdim_2005_Mech.Ageing.Dev_126_317 Bifunctional drug derivatives of MAO-B inhibitor rasagiline and iron chelator VK-28 as a more effective approach to treatment of brain ageing and ageing neurodegenerative diseases
Youdim_2005_Trends.Pharmacol.Sci_26_27 Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders
Youdim_2005_J.Neural.Transm.(Vienna)_112_519 CNS Targets for multi-functional drugs in the treatment of Alzheimer's and Parkinson's diseases
Greig_2005_Proc.Natl.Acad.Sci.U.S.A_102_17213 Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent
Carmona_2005_Eur.J.Pharmacol_517_186 Intravenous butyrylcholinesterase administration and plasma and brain levels of cocaine and metabolites in rats
Luo_2005_J.Med.Chem_48_986 Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine
Luo_2005_J.Org.Chem_70_6171 Syntheses of tetrahydrofurobenzofurans and dihydromethanobenzodioxepines from 5-hydroxy-3-methyl-3H-benzofuran-2-one. Rearrangement and ring expansion under reductive conditions on treatment with hydrides
Bourne_2005_Chem.Biol.Interact_157-158_159 Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE
Ahmad_2005_Chem.Pharm.Bull.(Tokyo)_53_378 Three new cholinesterase-inhibiting cis-clerodane diterpenoids from Otostegia limbata
Morita_2005_Brain.Res_1057_153 Inhibition of serotonin transporters by cocaine and meprylcaine through 5-TH2C receptor stimulation facilitates their seizure activities
Miyamoto_2005_J.Pestic.Sci_30_31 Oxidative Glutathione Conjugation and Its Novel Role in Activation of the Organophosphorus Insecticide Prothiofos
Wang_2005_Bioorg.Med.Chem.Lett_15_4510 Facile synthesis and PET imaging of a novel potential heart acetylcholinesterase tracer N-[11C]methyl-3-[[(dimethylamino)carbonyl]oxy]-2-(2',2'-diphenylpropionoxymethyl) pyridinium
Burridge_2005_Ecotoxicol.Environ.Saf_60_277 Seasonal lethality of the organophosphate pesticide, azamethiphos to female American lobster (Homarus americanus)
Cakir_2005_Food.Chem.Toxicol_43_443 Genotoxicity testing of some organophosphate insecticides in the Drosophila wing spot test
Olivera-Bravo_2005_Br.J.Pharmacol_144_88 The acetylcholinesterase inhibitor BW284c51 is a potent blocker of Torpedo nicotinic AchRs incorporated into the Xenopus oocyte membrane
Hoehamer_2005_J.Agric.Food.Chem_53_90 Purification and partial characterization of an acid phosphatase from Spirodela oligorrhiza and its affinity for selected organophosphate pesticides
Li_2005_Pestic.Biochem.Physiol_81_145 Toxicological and biochemical characterization of coumaphos resistance in the San Roman strain of Boophilus microplus (Acari: Ixodidae)
Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog Diazoxon studied by electrospray ionization ion trap mass spectrometry
O'Leary_2005_Pharmacogenet.Genomics_15_51 Genetic and other sources of variation in the activity of serum paraoxonase\/diazoxonase in humans: consequences for risk from exposure to diazinon
Thompson_2005_Ecotoxicology_14_757 The effects of four insect growth-regulating (IGR) insecticides on honeybee (Apis mellifera L.) colony development, queen rearing and drone sperm production
Roman_2005_Brain.Res_1061_73 Nicotinic-receptor potentiator drugs, huprine X and galantamine, increase ACh release by blocking AChE activity but not acting on nicotinic receptors
Sadzuka_2005_J.Control.Release_108_453 Liposomalization of SN-38 as active metabolite of CPT-11
Cecchin_2005_Clin.Cancer.Res_11_6901 Carboxylesterase isoform 2 mRNA expression in peripheral blood mononuclear cells is a predictive marker of the irinotecan to SN38 activation step in colorectal cancer patients
Hyatt_2005_Chem.Biol.Interact_157-158_247 Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11
Thatte_2005_Curr.Opin.Investig.Drugs_6_729 Phenserine Axonyx
Greig_2005_Curr.Alzheimer.Res_2_281 An overview of phenserine tartrate, a novel acetylcholinesterase inhibitor for the treatment of Alzheimer's disease
Greig_2005_Curr.Alzheimer.Res_2_483 Anticholinesterase and pharmacokinetic profile of phenserine in healthy elderly human subjects
Janas_2005_Life.Sci_76_1073 The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats
Massicotte_2005_Neurotox.Res_7_203 Effects of organophosphorus compounds on ATP production and mitochondrial integrity in cultured cells
Borlongan_2005_Brain.Res_1038_50 Methanesulfonyl fluoride, an acetylcholinesterase inhibitor, attenuates simple learning and memory deficits in ischemic rats
Byers_2005_Brain.Res.Dev.Brain.Res_158_13 Prenatal exposure to the acetylcholinesterase inhibitor methanesulfonyl fluoride alters forebrain morphology and gene expression
Haigh_2005_Chem.Biol.Interact_157-158_381 Inhibition of guinea pig hemi-diaphragm acetylcholinesterase activity by pyridostigmine bromide and protection against soman toxicity
Gordon_2005_Chem.Biol.Interact_157-158_239 Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman
Griffiths_2005_Int.Immunopharmacol_5_525 A T-cell-dependent humoral immune response is preserved during the administration of the nerve agent pre-treatment pyridostigmine bromide in a murine model
Ryu_2005_Nucl.Med.Biol_32_185 Synthesis and evaluation of 2-[18F]fluoro-CP-118,954 for the in vivo mapping of acetylcholinesterase
Espinosa_2005_Pest.Manag.Sci_61_1009 Metabolic mechanisms of insecticide resistance in the western flower thrips, Frankliniella occidentalis (Pergande)
Wu_2005_Pestic.Biochem.Physiol_82_79 Susceptibilities to methamidophos and enzymatic characteristics in 18 species of pest insects and their natural enemies in crucifer vegetable crops
Liu_2005_J.Med.Entomol_42_815 Chlorpyrifos resistance in mosquito Culex quinquefasciatus
Singh_2005_Pest.Manag.Sci_61_204 Effect of binary combination of some plant-derived molluscicides with MGK-264 or piperonyl butoxide on the reproduction of the snail Lymnaea acuminata
Young_2005_Pest.Manag.Sci_61_397 The effect of piperonyl butoxide on pyrethroid-resistance-associated esterases in Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae).
Casida_2005_Chem.Biol.Interact_157-158_277 Serine hydrolase targets of organophosphorus toxicants
Quistad_2005_Toxicol.Appl.Pharmacol_205_149 Platelet-activating factor acetylhydrolase: selective inhibition by potent n-alkyl methylphosphonofluoridates
Redinbo_2005_Drug.Discov.Today_10_313 Mammalian carboxylesterases: from drug targets to protein therapeutics
Hyatt_2005_J.Med.Chem_48_5543 Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety
Kikuchi_2005_J.Med.Chem_48_2577 N-[18F] fluoroethylpiperidin-4ylmethyl acetate, a novel lipophilic acetylcholine analogue for PET measurement of brain acetylcholinesterase activity
Bohnen_2005_J.Neurol.Neurosurg.Psychiatry_76_315 Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer's disease
Bohnen_2005_Neurosci.Lett_380_127 Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease
Mariotta_2005_Lung_183_1 Time intervals (3' or 5') between dose steps can influence methacholine challenge test
Monteiro_2005_Ecotoxicol.Environ.Saf_62_341 Characterization of the cholinesterases present in head tissues of the estuarine fish Pomatoschistus microps: application to biomonitoring
Osawa_2005_Clin.Chim.Acta_351_65 Development and application of serum cholinesterase activity measurement using benzoylthiocholine iodide
Ng_2005_Biotechnol.Bioeng_89_88 Hydrolytic resolution of (R,S)-naproxen 2,2,2-trifluoroethyl thioester by Carica papaya lipase in water-saturated organic solvents
Xin_2005_World.J.Microbiol.Biotechnol_21_193 Lipase-catalyzed naproxen methyl ester hydrolysis in water-saturated ionic liquid: significantly enhanced enantioselectivity and stability
Kuca_2005_J.Toxicol.Environ.Health.A_68_677 A comparison of the potency of newly developed oximes (K005, K027, K033, K048) and currently used oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited rat brain acetylcholinesterase by in vitro methods
Kuca_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_75 New quaternary pyridine aldoximes as casual antidotes against nerve agents intoxications
Kim_2005_Bioorg.Med.Chem.Lett_15_2914 Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents
Cabal_2005_Ceska.Slov.Farm_54_192 [A comparison of the efficacy of the reactivators of acetylcholinesterase inhibited with tabun]
Sevelova_2005_Toxicology_207_1 Antidotal treatment of GF-agent intoxication in mice with bispyridinium oximes
Jun_2005_Chem.Biol.Interact_157-158_385 Comparison of ability of some oximes to reactivate sarin-inhibited brain acetylcholinesterase from different species
Kuca_2005_J.Appl.Toxicol_25_491 Effective bisquaternary reactivators of tabun-inhibited AChE
Kuca_2005_Acta.Medica.(Hradec.Kralove)_48_81 A comparison of the potency of the oxime HLo-7 and currently used oximes (HI-6, pralidoxime, obidoxime) to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods
Antonijevic_2005_Basic.Clin.Pharmacol.Toxicol_96_111 Efficacy of trimedoxime in mice poisoned with dichlorvos, heptenophos or monocrotophos
Kassa_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_419 A comparison of the potency of trimedoxime and other currently available oximes to reactivate tabun-inhibited acetylcholinesterase and eliminate acute toxic effects of tabun
Kuca_2005_J.Appl.Toxicol_25_271 Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain
Kiderlen_2005_Biochem.Pharmacol_69_1853 Formation and disposition of diethylphosphoryl-obidoxime, a potent anticholinesterase that is hydrolyzed by human paraoxonase (PON1)
Meyer_2005_Toxicol.Appl.Pharmacol_203_154 Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos
Slotkin_2005_Brain.Res.Dev.Brain.Res_157_172 Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination
Slotkin_2005_Brain.Res.Dev.Brain.Res_160_219 Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combination
Gijsenbergh_2005_Anesthesiology_103_695 First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide
Vandevoorde_2005_Biochem.Biophys.Res.Commun_337_104 Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase
Gustavsson_2005_Biomacromolecules_6_196 Modification of cellulose fiber surfaces by use of a lipase and a xyloglucan endotransglycosylase
Seltzer_2005_Expert.Opin.Drug.Metab.Toxicol_1_527 Donepezil: a review
Dexter_2005_J.Phys.Chem.B.Condens.Matter.Mater.Surf.Interfaces.Biophys_109_14750 Comment on Hofmeister series: the hydrolytic activity of Aspergillus niger lipase depends on specific anion effects
Wang_2005_J.Phys.Chem.B.Condens.Matter.Mater.Surf.Interfaces.Biophys_109_13761 Hydrogen-bonding interactions in the binding of loop 1 of fasciculin 2 to Torpedo californica acetylcholinesterase: a density functional theory study
Pinna_2005_J.Phys.Chem.B.Condens.Matter.Mater.Surf.Interfaces.Biophys_109_5406 Hofmeister series: the hydrolytic activity of Aspergillus niger lipase depends on specific anion effects
Walwaikar_2005_J.Indian.Med.Assoc_103_708 Evaluation of new gastro-intestinal prokinetic (ENGIP-II) study
Rao_2005_Int.J.Environ.Res.Public.Health_2_478 Changes in Behavior and Brain Acetylcholinesterase Activity in Mosquito Fish, Gambusia affinis in Response to the Sub-Lethal Exposure to Chlorpyrifos
Edwards_2005_Int.J.Environ.Res.Public.Health_2_430 Environmental Toxicology and Health Effects Associated with Methyl Parathion Exposure - A Scientific Review
Wheelock_2005_J.Pestic.Sci_30_75 Overview of Carboxylesterases and Their Role in the Metabolism of Insecticides
Tohnishi_2005_J.Pestic.Sci_30_354 Flubendiamide, a Novel Insecticide Highly Active against Lepidopterous Insect Pests
Shimada_2005_J.Pestic.Sci_30_214 Permethrin Resistance Mechanisms in the Beet Armyworm (Spodoptera exigua (Hubner))
Miyake_2005_J.Pestic.Sci_30_390 Fungicidial Activity of Benthiavalicarb-isopropyl against Phytophthora infestans and Its Controlling Activity against Late Blight Diseases
Yang_2005_J.Pestic.Sci_30_84 Adulticidal Activity of Five Essential Oils against Culex pipiens quinquefasciatus
Ikeda_2005_J.Pestic.Sci_30_22 Degradation of the Fungicide Benthiavalicarb-isopropyl in Soils
Ugenskiene_2005_Medicina.(Kaunas)_41_17 Genetic polymorphisms in chronic obstructive pulmonary disease
Vellas_2005_J.Nutr.Health.Aging_9_75 Impact of Nutritional Status on the Evolution of Alzheimer's Disease and on Response to Acetylcholinesterase Inhibitor Treatment
Yamochi_2005_Cancer.Res_65_1973 Regulation of p38 phosphorylation and topoisomerase IIalpha expression in the B-cell lymphoma line Jiyoye by CD26\/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin
Yu_2005_Biochim.Biophys.Acta_1686_238 Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3
Zhao_2005_Am.J.Physiol.Regul.Integr.Comp.Physiol_288_R188 Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats
Cummings_2005_J.Neurol.Neurosurg.Psychiatry_76_903 Cholinesterase inhibitors for treatment of dementia associated with Parkinson's disease
Bartolini_2005_Anal.Biochem_342_163 Batchwise covalent immobilization of human acetylcholinesterase: Kinetic and inhibition spectrophotometric studies
Meshorer_2005_Faseb.J_19_910 Chronic cholinergic imbalances promote brain diffusion and transport abnormalities
Chen_2005_Zhongguo.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_17_334 [Clinical analysis of successful treatment of 12 cases with acute organophosphorus pesticide poisoning.]
Grossberg_2005_CNS.Spectr_10_1 Cholinesterase inhibitors across stages of dementia and cognitive impairments in the elderly
Liu_2005_Zhongguo.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_17_632 [Evaluation of diagnosis value of serum cholinesterases on upper gastrointestinal hemorrhage caused by liver diseases.]
Talesa_2005_Chem.Biol.Interact_157-158_1 Preface. The VIII Meeting on Cholinesterases in Perugia
Rotundo_2005_Chem.Biol.Interact_157-158_15 Targeting acetylcholinesterase to the neuromuscular synapse
Radic_2005_Chem.Biol.Interact_157-158_133 Molecular basis of interactions of cholinesterases with tight binding inhibitors
Lintern_2005_Chem.Biol.Interact_157-158_327 Attenuation of the effects of physostigmine by hyoscine in guinea-pig brain cholinergic enzymes: Acetylcholinesterase
Yeh_2005_Aquaculture_243_383 Effects of an organophosphorus insecticide, trichlorfon, on hematological parameters of the giant freshwater prawn, Macrobrachium rosenbergii (de Man)
Sitja-Bobadilla_2005_Aquaculture_249_387 Effect of fish meal replacement by plant protein sources on non-specific defence mechanisms and oxidative stress in gilthead sea bream (Sparus aurata)
Mugnier_2005_Aquaculture_244_315 Response of the blue shrimp Litopenaeus stylirostris to temperature decrease and hypoxia in relation to molt stage
Castranova_2005_Aquaculture_246_413 The effects of stress on androgen production, spermiation response and sperm quality in high and low cortisol responsive domesticated male striped bass
Brun-Barale_2005_Pest.Manag.Sci_61_549 Involvement of a sodium channel mutation in pyrethroid resistance in Cydia pomonella L, and development of a diagnostic test
Garcia_2005_Pest.Manag.Sci_61_612 Toxic and repellent effects of Baccharis salicifolia essential oil on Tribolium castaneum
Kiran_2005_Pest.Manag.Sci_61_1016 Synthesis and bioactivity of some new N-aryl\/alkyl\/cyclohexyl-N-(2,3-dihydro-2-oxo-4H-benz[e][1,3,2]oxazaphosphorin-2-yl) ureas
Roditakis_2005_Pest.Manag.Sci_61_577 Insecticide resistance in Bemisia tabaci (Homoptera: Aleyrodidae) populations from Crete
Roux_2005_Pest.Manag.Sci_61_1089 Dominance variation across six herbicides of the Arabidopsis thaliana csr1-1 and csr1-2 resistance alleles
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Elghar_2005_J.Asia.Pac.Entomol_8_397 Monitoring and Characterization of Insecticide Resistance in the Cotton Leafworm, Spodoptera littoral is (Boisd.) (Lepidoptera: Noctuidae)
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Calabresi_2005_Arterioscler.Thromb.Vasc.Biol_25_1972 The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families
Hunter_2005_Biochem.Biophys.Res.Commun_332_982 NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24
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Lopez-Coviella_2005_Proc.Natl.Acad.Sci.U.S.A_102_6984 Bone morphogenetic protein 9 induces the transcriptome of basal forebrain cholinergic neurons
Maskos_2005_Nature_436_103 Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
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Samson_2005_Biochemistry_44_10926 Two-dimensional measurement of proton T1rho relaxation in unlabeled proteins: mobility changes in alpha-bungarotoxin upon binding of an acetylcholine receptor peptide
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Tomizawa_2005_Insect.Biochem.Mol.Biol_35_1347 Pharmacological profiles of recombinant and native insect nicotinic acetylcholine receptors
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Cerpa_2005_Mol.Aspects.Med_26_405 Is there a role for copper in neurodegenerative diseases?
Inestrosa_2005_IUBMB.Life_57_645 Copper brain homeostasis: role of amyloid precursor protein and prion protein
Kriz_2005_Neurobiol.Dis_18_409 Up-regulation of peripherin is associated with alterations in synaptic plasticity in CA1 and CA3 regions of hippocampus
Krnjevic_2005_Neurol.Res_27_129 From cAMP to adenosine: an illuminating shift of focus
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Monchanin_2005_Med.Sci.Sports.Exerc_37_1086 Hemorheology, sickle cell trait, and alpha-thalassemia in athletes: effects of exercise
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Fonck_2005_J.Neurosci_25_11396 Novel seizure phenotype and sleep disruptions in knock-in mice with hypersensitive alpha 4* nicotinic receptors
Gallopin_2005_Neurosci_134_1377 The endogenous somnogen adenosine excites a subset of sleep-promoting neurons via A2A receptors in the ventrolateral preoptic nucleus
Lummis_2005_Chem.Biol_12_993 A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor
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Exley_2005_Br.J.Pharmacol_146_15 Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors
Oliveira_2005_Neurosignals_14_262 Protein kinase A and Ca(v)1 (L-Type) channels are common targets to facilitatory adenosine A2A and muscarinic M1 receptors on rat motoneurons
Smulders_2005_Eur.J.Pharmacol_509_97 Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism
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Watson_2005_Neurology_65_1802 Alpha7-acetylcholine receptor antibodies in two patients with Rasmussen encephalitis
Boss_2005_Clin.Exp.Dermatol_30_557 Muscarinic cholinergic receptors in the human melanoma cell line SK-Mel 28: modulation of chemotaxis
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Metzger_2005_Cells.Tissues.Organs_180_96 Identification and functional characterization of the muscarinic receptor M3 in the human keratinocyte cell line HaCaT
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Orr-Urtreger_2005_Neuroreport_16_1123 Increased severity of experimental colitis in alpha 5 nicotinic acetylcholine receptor subunit-deficient mice
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Madhavan_2005_IUBMB.Life_57_719 Molecular regulation of postsynaptic differentiation at the neuromuscular junction
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Nunes-Tavares_2005_Med.Sci.Monit_11_BR100 Toxicity induced by Hg2+ on choline acetyltransferase activity from E. electricus (L.) electrocytes: the protective effect of 2,3 dimercapto-propanol (BAL)
Brudzynski_2005_Behav.Genet_35_85 Principles of rat communication: quantitative parameters of ultrasonic calls in rats
Brudzynski_2005_Neurosci.Biobehav.Rev_29_1169 Acoustic characteristics of air puff-induced 22-kHz alarm calls in direct recordings
Burgdorf_2005_Behav.Genet_35_67 Breeding for 50-kHz positive affective vocalization in rats
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Jones_2005_J.Pharmacol.Exp.Ther_312_1055 Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats
Lin_2005_Neuron_46_569 Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism
Myers_2005_Neuron_46_37 Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits
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Salgarelli_2005_Int.J.Oral.Maxillofac.Surg_34_27 Treatment of lower lip cancer: an experience of 48 cases
Thomsen_2005_J.Neurosci_25_8141 Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice
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Bohr_2005_Exp.Neurol_191_292 Cholinergic nicotinic receptor involvement in movement disorders associated with Lewy body diseases. An autoradiography study using [(125)I]alpha-conotoxinMII in the striatum and thalamus
Castillo_2005_J.Biol.Chem_280_27062 Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors
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Gahring_2005_J.Neuroimmunol_166_88 Pro-inflammatory cytokines modify neuronal nicotinic acetylcholine receptor assembly
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Gahring_2005_AAPS.J_7_E885 Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells
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Jakubik_2005_J.Pharmacol.Exp.Ther_313_688 Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators
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McGaughy_2005_J.Neurosci_25_10273 Cholinergic deafferentation of the entorhinal cortex in rats impairs encoding of novel but not familiar stimuli in a delayed nonmatch-to-sample task
Novakova_2005_Brain.Res_1062_101 Chronic treatment with amyloid beta(1-42) inhibits non-cholinergic high-affinity choline transport in NG108-15 cells through protein kinase C signaling
Ortiz_2005_J.Neurochem_95_1585 The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits
Paraoanu_2005_Neurosci_132_665 Cytochrome-c oxidase is one of several genes elevated in marginal retina of the chick embryo
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Sarter_2005_Brain.Res.Brain.Res.Rev_48_98 Unraveling the attentional functions of cortical cholinergic inputs: interactions between signal-driven and cognitive modulation of signal detection
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Texido_2005_Br.J.Pharmacol_145_672 Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity
Cavallini_2005_Neurochem.Int_47_482 Effects of chemical ischemia in cerebral cortex slices. Focus on nitric oxide
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Philibin_2005_Pharmacol.Biochem.Behav_80_87 Differential behavioral responses to nicotine in Lewis and Fischer-344 rats
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Chen_2005_J.Neurosci_25_507 Specific modulation of Na+ channels in hippocampal neurons by protein kinase C epsilon
Cymes_2005_Nature_438_975 Probing ion-channel pores one proton at a time
Dennis_2005_Cancer.Epidemiol.Biomarkers.Prev_14_764 The biology of tobacco and nicotine: bench to bedside
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Fischer_2005_J.Physiol_563_119 Selective deletion of the alpha5 subunit differentially affects somatic-dendritic versus axonally targeted nicotinic ACh receptors in mouse
Giniatullin_2005_Trends.Neurosci_28_371 Desensitization of nicotinic ACh receptors: shaping cholinergic signaling
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Lamb_2005_J.Mol.Neurosci_27_13 Inhibition of neuronal nicotinic acetylcholine receptor channels expressed in Xenopus oocytes by beta-amyloid1-42 peptide
Marostica_2005_Life.Sci_77_656 Effects of testosterone on muscarinic acetylcholine receptors in the rat epididymis
Marritt_2005_Mol.Pharmacol_68_1656 Nicotinic cholinergic receptors in the rat retina: simple and mixed heteromeric subtypes
McCallum_2005_Mol.Pharmacol_68_737 Decrease in alpha3*\/alpha6* nicotinic receptors but not nicotine-evoked dopamine release in monkey brain after nigrostriatal damage
Papke_2005_Mol.Pharmacol_67_1977 The effects of subunit composition on the inhibition of nicotinic receptors by the amphipathic blocker 2,2,6,6-tetramethylpiperidin-4-yl heptanoate
Papke_2005_Eur.J.Pharmacol_524_11 Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human alpha7 receptors expressed in Xenopus oocytes
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Jori_2005_Cell.Death.Differ_12_65 RB and RB2\/p130 genes demonstrate both specific and overlapping functions during the early steps of in vitro neural differentiation of marrow stromal stem cells
Bytyqi_2005_Anat.Embryol.(Berl)_209_217 Lamina formation in the Mongolian gerbil retina (Meriones unguiculatus)
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Blake_2005_Adv.Exp.Med.Biol_564_97 Glycosylation defects and muscular dystrophy
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Aharoni_2005_Chem.Biol_12_1281 High-throughput screening of enzyme libraries: thiolactonases evolved by fluorescence-activated sorting of single cells in emulsion compartments
Aharoni_2005_Nat.Genet_37_73 The 'evolvability' of promiscuous protein functions
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Briviba_2005_Redox.Rep_10_325 A half-marathon and a marathon run induce oxidative DNA damage, reduce antioxidant capacity to protect DNA against damage and modify immune function in hobby runners
Bub_2005_Br.J.Nutr_93_291 Paraoxonase 1 Q192R (PON1-192) polymorphism is associated with reduced lipid peroxidation in healthy young men on a low-carotenoid diet supplemented with tomato juice
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Deakin_2005_Atherosclerosis_179_17 Very low density lipoproteins provide a vector for secretion of paraoxonase-1 from cells
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Fuhrman_2005_Atherosclerosis_180_55 Paraoxonase 1 (PON1) is present in postprandial chylomicrons
Gaidukov_2005_Biochemistry_44_11843 High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I
Garin_2005_J.Clin.Endocrinol.Metab_90_2264 Small, dense lipoprotein particles and reduced paraoxonase-1 in patients with the metabolic syndrome
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Kalmar_2005_Diabetes.Metab_31_574 Correlation between the activities of lipoprotein lipase and paraoxonase in type 2 diabetes mellitus
Kiss_2005_Orv.Hetil_146_2395 [Analysis of paraoxonase activity and lipid profile in lupus patients]
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Mackness_2005_J.Intern.Med_258_363 The paraoxonase-2-310 polymorphism is associated with the presence of microvascular complications in diabetes mellitus
Moore_2005_Circ.Res_97_763 Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation
Navab_2005_Arterioscler.Thromb.Vasc.Biol_25_1426 D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice
Navab_2005_Circ.Res_97_524 Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice
Navab_2005_Arterioscler.Thromb.Vasc.Biol_25_1325 Apolipoprotein A-I mimetic peptides
Navab_2005_Arterioscler.Thromb.Vasc.Biol_25_1932 An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice
Ng_2005_Free.Radic.Biol.Med_38_153 The paraoxonase gene family and atherosclerosis
Roodveldt_2005_Curr.Opin.Struct.Biol_15_50 Directed evolution of proteins for heterologous expression and stability
Rosenblat_2005_Atherosclerosis_179_69 Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine
Rozenberg_2005_Atherosclerosis_181_9 Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice
Shamir_2005_Free.Radic.Biol.Med_39_336 Paraoxonases (PONs) 1, 2, and 3 are expressed in human and mouse gastrointestinal tract and in Caco-2 cell line: selective secretion of PON1 and PON2
Trudel_2005_J.Cell.Biochem_96_404 Iron-ascorbic acid-induced oxidant stress and its quenching by paraoxonase 1 in HDL and the liver: comparison between humans and rats
van Himbergen_2005_J.Lipid.Res_46_445 Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia
van Himbergen_2005_Biochem.Biophys.Res.Commun_333_787 Paraoxonase-1 and linoleic acid oxidation in familial hypercholesterolemia
Wetmur_2005_Nucleic.Acids.Res_33_2615 Molecular haplotyping by linking emulsion PCR: analysis of paraoxonase 1 haplotypes and phenotypes
Yeung_2005_FEBS.J_272_2225 Analysis of active-site amino-acid residues of human serum paraoxonase using competitive substrates
Beltowski_2005_Postepy.Hig.Med.Dosw.(Online)_59_392 Protein homocysteinylation: a new mechanism of atherogenesis?
Beltowski_2005_Pharmacol.Res_51_523 Differential effect of antioxidant treatment on plasma and tissue paraoxonase activity in hyperleptinemic rats
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Ferretti_2005_Mult.Scler_11_677 Increased levels of lipid hydroperoxides in plasma of patients with multiple sclerosis: a relationship with paraoxonase activity
Martinelli_2005_Clin.Exp.Med_5_20 Interaction between metabolic syndrome and PON1 polymorphisms as a determinant of the risk of coronary artery disease
Franceschi_2005_Mech.Ageing.Dev_126_351 Genes involved in immune response\/inflammation, IGF1\/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians
Kiortsis_2005_Angiology_56_451 Lack of association between carotid intima-media thickness and PAF-acetylhydrolase mass and activity in patients with primary hyperlipidemia
Milionis_2005_Thyroid_15_455 Thyroid substitution therapy induces high-density lipoprotein-associated platelet-activating factor-acetylhydrolase in patients with subclinical hypothyroidism: a potential antiatherogenic effect
Rainwater_2005_J.Lipid.Res_46_1450 Determinants of variation in serum paraoxonase enzyme activity in baboons
Rizos_2005_Prostaglandins.Leukot.Essent.Fatty.Acids_72_203 Lipoprotein-associated PAF-acetylhydrolase activity in subjects with the metabolic syndrome
Bartlett_2005_J.Biol.Chem_280_21837 Single cell analysis and temporal profiling of agonist-mediated inositol 1,4,5-trisphosphate, Ca2+, diacylglycerol, and protein kinase C signaling using fluorescent biosensors
Bravo_2005_Biochemistry_44_7955 Mutational and pH analysis of ionic residues in transmembrane domains of vesicular acetylcholine transporter
Bravo_2005_Neurochem.Int_47_243 New transport assay demonstrates vesicular acetylcholine transporter has many alternative substrates
Willets_2005_J.Biol.Chem_280_18950 Roles of phosphorylation-dependent and -independent mechanisms in the regulation of M1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 in hippocampal neurons
Young_2005_Mol.Cell.Neurosci_30_48 Muscarinic acetylcholine receptor activation enhances hippocampal neuron excitability and potentiates synaptically evoked Ca(2+) signals via phosphatidylinositol 4,5-bisphosphate depletion
Zea-Ponce_2005_Bioorg.Med.Chem_13_745 Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter
Fischer_2005_J.Nutr_135_826 Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level
Dimitropoulou_2005_Am.J.Respir.Cell.Mol.Biol_32_239 Estrogen reduces carbachol-induced constriction of asthmatic airways by stimulating large-conductance voltage and calcium-dependent potassium channels
Martin_2005_Semin.Pediatr.Neurol_12_152 The dystroglycanopathies: the new disorders of O-linked glycosylation
Nathan_2005_Brain.Res_1041_87 Delayed olfactory nerve regeneration in ApoE-deficient mice
Arredondo_2005_Am.J.Pathol_167_1531 Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in Pemphigus
Arredondo_2005_Am.J.Pathol_166_597 Receptor-mediated tobacco toxicity: regulation of gene expression through alpha3beta2 nicotinic receptor in oral epithelial cells
Arredondo_2005_J.Invest.Dermatol_125_1236 Biological effects of SLURP-1 on human keratinocytes
Chernyavsky_2005_J.Biol.Chem_280_39220 The Ras\/Raf-1\/MEK1\/ERK signaling pathway coupled to integrin expression mediates cholinergic regulation of keratinocyte directional migration
Gosens_2005_Am.J.Respir.Crit.Care.Med_171_1096 Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling
Helisch_2005_Eur.J.Nucl.Med.Mol.Imaging_32_1324 Demonstration of pulmonary beta2-adrenergic receptor binding in vivo with [18F]fluoroethyl-fenoterol in a guinea pig model
Lips_2005_Placenta_26_735 Nicotinic acetylcholine receptors in rat and human placenta
Wessler_2005_Bundesgesundheitsblatt.Gesundheitsforschung.Gesundheitsschutz_48_155 [Reorganization of the procedures and the tasks of the responsible ethics committees after the 12th AMG amendment. Concepts of the permanent working group of the medical ethics committees in Germany]
Yamada_2005_Life.Sci_77_1935 Expression of acetylcholine (ACh) and ACh-synthesizing activity in Archaea
Moser_2005_Toxicol.Sci_86_375 Neurobehavioral effects of chronic dietary and repeated high-level spike exposure to chlorpyrifos in rats
Padilla_2005_Toxicol.Sci_88_161 Neurochemical effects of chronic dietary and repeated high-level acute exposure to chlorpyrifos in rats
Bolanos-Meade_2005_Am.J.Hematol_78_306 Hydroxychloroquine causes severe vacuolar myopathy in a patient with chronic graft-versus-host disease
Chen_2005_Brain.Res_1057_88 Robust axonal sprouting and synaptogenesis in organotypic slice cultures of rat cerebellum exposed to increased potassium chloride
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Schneggenburger_2005_Curr.Opin.Neurobiol_15_266 Presynaptic calcium and control of vesicle fusion
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Mateo_2005_Org.Biomol.Chem_3_2832 Synthesis of phenazine derivatives for use as precursors to electrochemically generated bases
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Riganti_2005_Br.J.Pharmacol_146_1096 Long-term exposure to the new nicotinic antagonist 1,2-bisN-cytisinylethane upregulates nicotinic receptor subtypes of SH-SY5Y human neuroblastoma cells
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Tsuneki_2005_Biol.Pharm.Bull_28_611 Marine alkaloids (-)-pictamine and (-)-lepadin B block neuronal nicotinic acetylcholine receptors
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Jones_2005_Genomics_85_176 The nicotinic acetylcholine receptor gene family of the malaria mosquito, Anopheles gambiae
Jones_2005_Invert.Neurosci_5_147 Sgbeta1, a novel locust (Schistocerca gregaria) non-alpha nicotinic acetylcholine receptor-like subunit with homology to the Drosophila melanogaster Dbeta1 subunit
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Raymond-Delpech_2005_Invert.Neurosci_5_119 Ion channels: molecular targets of neuroactive insecticides
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Barton_2005_Neurosci_136_563 The seizure-related phenotype of brain-derived neurotrophic factor knockdown mice
Hansel_2005_Chest_128_1974 Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma
Itoh_2005_J.Biol.Chem_280_26383 Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells
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Maneechotesuwan_2005_Chest_128_1936 Formoterol attenuates neutrophilic airway inflammation in asthma
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Bayorh_2005_Am.J.Hypertens_18_1496 Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension
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Kommalage_2005_Eur.J.Pharmacol_525_69 Involvement of spinal GABA receptors in the regulation of intraspinal acetylcholine release
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Liu_2005_BMC.Pharmacol_5_8 Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport
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Mansfield_2005_Br.J.Pharmacol_144_1089 Muscarinic receptor subtypes in human bladder detrusor and mucosa, studied by radioligand binding and quantitative competitive RT-PCR: changes in ageing
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Aucoin_2005_Neurosci_132_73 Selective cholinergic denervation, independent from oxidative stress, in a mouse model of Alzheimer's disease
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Drewes_2005_J.Pain_6_455 Statistical modeling of the response characteristics of mechanosensitive stimuli in the human esophagus
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Coccini_2005_Environ.Toxicol.Pharmacol_19_715 Lymphocyte muscarinic receptors and platelet monoamine oxidase-B as biomarkers of CNS function: effects of age and gender in healthy humans
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Falk_2005_Neurosci_132_389 Smoking during early pregnancy affects the expression pattern of both nicotinic and muscarinic acetylcholine receptors in human first trimester brainstem and cerebellum
Yoshikawa_2005_Metabolism_54_247 Evidence for functional nicotinic receptors on pancreatic beta cells
Hepler_2005_Biochemistry_44_5495 Novel activity of RGS14 on Goalpha and Gialpha nucleotide binding and hydrolysis distinct from its RGS domain and GDI activity
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Johren_2005_Arch.Pharm.(Weinheim)_338_260 Different environments for a realistic simulation of GPCRs-application to the M2 muscarinic receptor
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Buchanan_2005_Exp.Neurol_193_489 New light on an old paradox: site-dependent effects of carbachol on circadian rhythms
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Ehlert_2005_J.Pharmacol.Exp.Ther_312_592 Comparison of the antimuscarinic action of p-fluorohexahydrosiladifenidol in ileal and tracheal smooth muscle
Miller_2005_Neurosci_136_531 Midbrain muscarinic receptors modulate morphine-induced accumbal and striatal dopamine efflux in the rat
Chen_2005_Inflamm.Res_54_119 Pharmacological characterization of P2X7 receptors in rat peritoneal cells
Nakane_2005_Neuropharmacol_49_112 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist
Adler_2005_Am.J.Psychiatry_162_386 Improved p50 auditory gating with ondansetron in medicated schizophrenia patients
Ayers_2005_AAPS.J_7_E678 Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the alpha4beta2 nicotinic acetylcholine receptor subtype using nonlinear techniques
Ayers_2005_AAPS.J_7_E752 A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine
Bespalov_2005_Neuropharmacol_49 Suppl 1_167 Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats
Blair_2005_Ann.Epidemiol_15_279 Mortality among participants in the agricultural health study
Bodnar_2005_J.Med.Chem_48_905 Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors
Bruijnzeel_2005_Brain.Res_1058_91 Decreased sensitivity to the effects of dopamine D1-like, but not D2-like, receptor antagonism in the posterior hypothalamic region\/anterior ventral tegmental area on brain reward function during chronic exposure to nicotine in rats
Coe_2005_J.Med.Chem_48_3474 Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation
Coe_2005_Bioorg.Med.Chem.Lett_15_4889 3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation
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Freedman_2005_Dialogues.Clin.Neurosci_7_17 Early biomarkers of psychosis
Gundisch_2005_Synapse_55_89 In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors
Huang_2005_J.Am.Chem.Soc_127_14401 Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity
Ingram_2005_Dig.Liver.Dis_37_832 Plasma fibrinogen in ulcerative colitis: the effect of disease activity and nicotine therapy in a randomised controlled trial
Kenny_2005_J.Neurosci_25_6208 Conditioned nicotine withdrawal profoundly decreases the activity of brain reward systems
Lindblom_2005_Naunyn.Schmiedebergs.Arch.Pharmacol_372_182 Active immunisation against nicotine blocks the reward facilitating effects of nicotine and partially prevents nicotine withdrawal in the rat as measured by dopamine output in the nucleus accumbens, brain reward thresholds and somatic signs
Obrzut_2005_Nucl.Med.Biol_32_869 Whole-body radiation dosimetry of 2-[18F]Fluoro-A-85380 in human PET imaging studies
Papke_2005_Bioorg.Med.Chem.Lett_15_3874 The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion
Paterson_2005_Neuropharmacol_49_953 Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function
Paterson_2005_Neuropsychopharmacology_30_119 Repeated administration of the GABAB receptor agonist CGP44532 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine-seeking in rats
Rauhut_2005_Nicotine.Tob.Res_7_901 Tolerance does not develop to the decrease in nicotine self-administration produced by repeated bupropion administration
Sumithran_2005_AAPS.J_7_E201 Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity
Vaupel_2005_J.Pharmacol.Exp.Ther_312_355 Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography
Wei_2005_Life.Sci_78_495 Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: affinity for neuronal nicotinic acetylcholine receptors
Wilkins_2005_AAPS.J_7_E922 N-n-alkylnicotinium analogs, a novel class of antagonists at alpha 4 beta 2* nicotinic acetylcholine receptors: inhibition of S(-)-nicotine-evoked 86Rb+ efflux from rat thalamic synaptosomes
Xu_2005_Biol.Psychiatry_58_143 Brain activity in cigarette smokers performing a working memory task: effect of smoking abstinence
Zheng_2005_Bioorg.Med.Chem.Lett_15_4463 Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands
Zheng_2005_J.Med.Chem_48_5551 Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter
Zheng_2005_Bioorg.Med.Chem_13_3899 Lobelane analogues as novel ligands for the vesicular monoamine transporter-2
Czura_2005_J.Intern.Med_257_156 Autonomic neural regulation of immunity
Feuerbach_2005_Neuropharmacol_48_215 Coupling of human nicotinic acetylcholine receptors alpha 7 to calcium channels in GH3 cells
Gallowitsch-Puerta_2005_Ann.N.Y.Acad.Sci_1062_209 Immunologic role of the cholinergic anti-inflammatory pathway and the nicotinic acetylcholine alpha 7 receptor
Metz_2005_Nat.Immunol_6_756 It takes nerve to dampen inflammation
Saeed_2005_J.Exp.Med_201_1113 Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
van Westerloo_2005_J.Infect.Dis_191_2138 The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis
Sun_2005_Stem.Cells_23_931 Voltage-sensitive and ligand-gated channels in differentiating neural stem-like cells derived from the nonhematopoietic fraction of human umbilical cord blood
Tregellas_2005_Am.J.Psychiatry_162_391 FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia
Sadasivam_2005_J.Neurosci_25_10479 Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors
Smirnov_2005_J.Biol.Chem_280_41449 Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering
Williams_2005_J.Biol.Chem_280_1257 Ric-3 promotes functional expression of the nicotinic acetylcholine receptor alpha7 subunit in mammalian cells
Barco_2005_Neuron_48_123 Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture
Huang_2005_Learn.Mem_12_587 Theta frequency stimulation induces a local form of late phase LTP in the CA1 region of the hippocampus
Huang_2005_Proc.Natl.Acad.Sci.U.S.A_102_232 Theta frequency stimulation up-regulates the synaptic strength of the pathway from CA1 to subiculum region of hippocampus
Huang_2005_Proc.Natl.Acad.Sci.U.S.A_102_9365 Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation
Huxley_2005_Adv.Exp.Med.Biol_565_3 Early developments in muscle research and the role of new structural technologies
Huxley_2005_Adv.Exp.Med.Biol_565_37 Distribution of crossbridge states in contracting muscle
Udo_2005_Neuron_45_887 Serotonin-induced regulation of the actin network for learning-related synaptic growth requires Cdc42, N-WASP, and PAK in Aplysia sensory neurons
Wang_2005_Neuron_45_389 Presynaptic and postsynaptic roles of NO, cGK, and RhoA in long-lasting potentiation and aggregation of synaptic proteins
Akk_2005_J.Physiol_564_359 Activation of heteroliganded mouse muscle nicotinic receptors
Arnaud_2005_J.Phys.Chem.A_109_3767 Hydrogen-bond accepting strength of protonated nicotine
Forget_2005_Psychopharmacology.(Berl)_181_722 Cannabinoid CB1 receptors are involved in motivational effects of nicotine in rats
Hallermann_2005_J.Physiol_563_645 Short openings in high resolution single channel recordings of mouse nicotinic receptors
Levandoski_2005_Int.J.Parasitol_35_925 Single-channel properties of N- and L-subtypes of acetylcholine receptor in Ascaris suum
Lu_2005_J.Med.Chem_48_4576 Adamantyl cannabinoids: a novel class of cannabinergic ligands
Martin_2005_Parasitol_131 Suppl_S71 Drug resistance and neurotransmitter receptors of nematodes: recent studies on the mode of action of levamisole
Mordvintsev_2005_Comput.Biol.Chem_29_398 A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: comparison with long-chain alpha-neurotoxins and alpha-conotoxins
Nuutinen_2005_Eur.J.Pharmacol_515_83 Time and brain region specific up-regulation of low affinity neuronal nicotinic receptors during chronic nicotine administration in mice
Schnizler_2005_J.Biol.Chem_280_16254 A novel chloride channel in Drosophila melanogaster is inhibited by protons
Thany_2005_Gene_344_125 Apisalpha2, Apisalpha7-1 and Apisalpha7-2: three new neuronal nicotinic acetylcholine receptor alpha-subunits in the honeybee brain
Thany_2005_Brain.Res_1039_216 Nicotine injected into the antennal lobes induces a rapid modulation of sucrose threshold and improves short-term memory in the honeybee Apis mellifera
Tomimoto_2005_Neurology_65_179\; author reply 179 Absence of cholinergic deficits in pure vascular dementia
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Vulfius_2005_Neurosci.Lett_373_232 Diversity of nicotinic receptors mediating Cl- current in Lymnaea neurons distinguished with specific agonists and antagonist
Williams_2005_Genetics_169_1779 Characterization of Mos1-mediated mutagenesis in Caenorhabditis elegans: a method for the rapid identification of mutated genes
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Barbayianni_2005_J.Org.Chem_70_8730 Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties
Bornscheuer_2005_Chem.Biol_12_859 Deep sea mining for unique biocatalysts
Ganske_2005_Org.Lett_7_3097 Lipase-catalyzed glucose fatty acid ester synthesis in ionic liquids
Odman_2005_J.Org.Chem_70_9551 Chemoenzymatic dynamic kinetic resolution of acyloins
Schmidt_2005_Biomol.Eng_22_51 High-throughput assays for lipases and esterases
de la Torre_2005_Breast.Cancer.Res_7_R345 Muscarinic receptors participation in angiogenic response induced by macrophages from mammary adenocarcinoma-bearing mice
Rimmaudo_2005_Biochem.Biophys.Res.Commun_334_1359 Muscarinic receptors are involved in LMM3 tumor cells proliferation and angiogenesis
Ohneda_2005_Appl.Environ.Microbiol_71_4856 Isolation and characterization of Aspergillus oryzae vacuolar protein sorting mutants
Eddleston_2005_Lancet_366_1452 Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study
Thiermann_2005_Toxicology_214_190 Effects of oximes on muscle force and acetylcholinesterase activity in isolated mouse hemidiaphragms exposed to paraoxon
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Bernhardt_2005_Angew.Chem.Int.Ed.Engl_44_2742 Molecular basis of perhydrolase activity in serine hydrolases
Kazlauskas_2005_Curr.Opin.Chem.Biol_9_195 Enhancing catalytic promiscuity for biocatalysis
Katsuki_2005_Eur.J.Pharmacol_508_85 Tetraethylammonium exacerbates ischemic neuronal injury in rat cerebrocortical slice cultures
Kume_2005_Eur.J.Pharmacol_527_77 Up-regulation of nicotinic acetylcholine receptors by central-type acetylcholinesterase inhibitors in rat cortical neurons
Dick_2005_Chem.Res.Toxicol_18_317 Identification of aldehyde oxidase as the neonicotinoid nitroreductase
Dobrovolsky_2005_Biochim.Biophys.Acta_1724_163 Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype
Kanne_2005_Chem.Res.Toxicol_18_1479 Neonicotinoid nitroguanidine insecticide metabolites: synthesis and nicotinic receptor potency of guanidines, aminoguanidines, and their derivatives
Kanne_2005_Bioorg.Med.Chem.Lett_15_877 6'-Methylpyrido[3,4-b]norhomotropane: synthesis and outstanding potency in relation to the alpha4beta2 nicotinic receptor pharmacophore model
Pabarcus_2005_Protein.Expr.Purif_44_39 Cloning, expression, and catalytic triad of recombinant arylformamidase
Tomizawa_2005_Annu.Rev.Pharmacol.Toxicol_45_247 Neonicotinoid insecticide toxicology: mechanisms of selective action
Philippens_2005_Pharmacol.Biochem.Behav_82_125 Stress adversely affects efficacy of physostigmine-scopolamine pretreatment against soman in guinea pigs
Changeux_2005_Science_308_1424 Allosteric mechanisms of signal transduction
Grutter_2005_Proc.Natl.Acad.Sci.U.S.A_102_18207 Molecular tuning of fast gating in pentameric ligand-gated ion channels
Hestrin_2005_Trends.Neurosci_28_304 Electrical synapses define networks of neocortical GABAergic neurons
Lambe_2005_J.Neurosci_25_5225 Hypocretin and nicotine excite the same thalamocortical synapses in prefrontal cortex: correlation with improved attention in rat
Makhaeva_2005_Dokl.Biochem.Biophys_400_92 Fluorinated alpha-aminophosphonates--a new type of irreversible inhibitors of serine hydrolases
Sokolovskaya_2005_Biotechnol.Lett_27_1211 Improved electrochemical analysis of neuropathy target esterase activity by a tyrosinase carbon paste electrode modified by 1-methoxyphenazine methosulfate
Berrettini_2005_Psychiatry.(Edgmont)_2_40 Promising pharmacotherapy on the horizon for nicotine dependence
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Lohoff_2005_Psychiatry.Res_135_171 No association between common variations in the neuronal nicotinic acetylcholine receptor alpha2 subunit gene (CHRNA2) and bipolar I disorder
Munafo_2005_Pharmacogenomics_6_211 Pharmacogenetics and nicotine addiction treatment
Okerberg_2005_Proc.Natl.Acad.Sci.U.S.A_102_4996 High-resolution functional proteomics by active-site peptide profiling
Jerng_2005_J.Physiol_568_767 Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties
Ren_2005_Mol.Cell.Neurosci_29_320 Transmembrane interaction mediates complex formation between peptidase homologues and Kv4 channels
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Gill_2005_J.Neurosci.Methods_148_26 Exposure of nuclear antigens in formalin-fixed, paraffin-embedded necropsy human spinal cord tissue: detection of NeuN
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Grinevich_2005_J.Pharmacol.Exp.Ther_312_619 Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit
Rusted_2005_Psychopharmacology.(Berl)_182_355 Nicotine improves memory for delayed intentions
Rycroft_2005_Psychopharmacology.(Berl)_181_160 Acute effects of nicotine on visual search tasks in young adult smokers
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Santarossa_2005_FEBS.Lett_579_2383 Mutations in the lid region affect chain length specificity and thermostability of a Pseudomonas fragi lipase
El Hassani_2005_Pharmacol.Biochem.Behav_82_30 Effects of sublethal doses of fipronil on the behavior of the honeybee (Apis mellifera)
Dudai_2005_Nature_434_567 The Janus face of Mnemosyne
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Abdel-Rahman_2005_Toxicol.Sci_85_624 Variability in human sensitivity to 1,3-butadiene: influence of polymorphisms in the 5'-flanking region of the microsomal epoxide hydrolase gene (EPHX1)
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Ahmad_2005_Biol.Trace.Elem.Res_103_59 Sodium selenite stimulates neurobehavior and neurochemical activities in rats
Ahren_2005_Diabetologia_48_605 What mediates the benefits associated with dipeptidyl peptidase-IV inhibition?
Ahren_2005_Endocrinology_146_2055 Inhibition of dipeptidyl peptidase-4 augments insulin secretion in response to exogenously administered glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide, pituitary adenylate cyclase-activating polypeptide, and gastrin-releasing peptide in mice
Akk_2005_J.Neurosci_25_1992 Galantamine activates muscle-type nicotinic acetylcholine receptors without binding to the acetylcholine-binding site
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Alisky_2005_J.Acquir.Immune.Defic.Syndr_38_113 Could cholinesterase inhibitors and memantine alleviate HIV dementia?
Alwahhabi_2005_J.Psychopharmacol_19_214 Successfully switching acetylcholinesterase inhibitor therapy in probable Lewy body dementia
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Aracava_2005_J.Pharmacol.Exp.Ther_312_1195 Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons
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Ballinger_2005_Free.Radic.Biol.Med_38_515 Antioxidant-mediated augmentation of ozone-induced membrane oxidation
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Banks_2005_Environ.Int_31_351 Chlorpyrifos in surface waters before and after a federally mandated ban
Barteri_2005_Biophys.Chem_113_245 Structural and kinetic effects of mobile phone microwaves on acetylcholinesterase activity
Bartolini_2005_J.Chromatogr.A_1065_135 Choosing the right chromatographic support in making a new acetylcholinesterase-micro-immobilised enzyme reactor for drug discovery
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Batuello_2005_N.Engl.J.Med_352_420 Increased serum lipase in West Nile virus infection
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Bloch-Shilderman_2005_J.Pharmacol.Exp.Ther_313_1082 Subcellular alterations of protein kinase C isozymes in the rat brain after organophosphate poisoning
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Bolognesi_2005_J.Med.Chem_48_24 Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation
Bonner_2005_Environ.Health.Perspect_113_285 Occupational exposure to carbofuran and the incidence of cancer in the Agricultural Health Study
Booth_2005_Ecotoxicol.Environ.Saf_60_176 Hazard evaluation for northern bobwhite quail (Colinus virginianus) exposed to chlorpyrifos-treated turf and seed
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Britti_2005_J.Am.Vet.Med.Assoc_226_951 Evaluation of serum enzyme activities as predictors of passive transfer status in lambs
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Buckley_2005_Cochrane.Database.Syst.Rev__CD005085 Oximes for acute organophosphate pesticide poisoning
Bula_2005_Rev.Med.Suisse_1_27 [Gerontology]
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Busso_2005_Am.J.Pathol_166_433 Circulating CD26 is negatively associated with inflammation in human and experimental arthritis
Bustos-Obregon_2005_Asian.J.Androl_7_71 Lepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice
Campiani_2005_J.Med.Chem_48_1919 Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors
Camps_2005_J.Med.Chem_48_1701 Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors
Canadas_2005_Toxicol.Sci_85_944 Long-term neurotoxicity of chlorpyrifos: spatial learning impairment on repeated acquisition in a water maze
Cao_2005_Colloids.Surf.B.Biointerfaces_40_75 The interaction between OPH and paraoxon at the air-water interface studied by AFM and epifluorescence microscopies
Carlqvist_2005_Chembiochem_6_331 Exploring the active-site of a rationally redesigned lipase for catalysis of Michael-type additions
Carvajal_2005_Toxicol.Sci_84_360 Neuroanatomical targets of the organophosphate chlorpyrifos by c-fos immunolabeling
Chang_2005_Appl.Microbiol.Biotechnol_67_215 Multiple mutagenesis of the Candida rugosa LIP1 gene and optimum production of recombinant LIP1 expressed in Pichia pastoris
Chen_2005_Toxicol.Sci_83_149 Effects of trichloroethylene and perchloroethylene on muscle contractile responses and epithelial prostaglandin release and acetylcholinesterase activity in swine trachea
Chiang_2005_Neurobiol.Dis_18_40 Skin denervation, neuropathology, and neuropathic pain in a laser-induced focal neuropathy
Chih_2005_Science_307_1324 Control of excitatory and inhibitory synapse formation by neuroligins
Chon_2005_Environ.Monit.Assess_101_1 Movement behaviour of Medaka (Oryzias latipes) in response to sublethal treatments of diazinon and cholinesterase activity in semi-natural conditions
Choudhary_2005_Steroids_70_295 Cholinesterase inhibitory pregnane-type steroidal alkaloids from Sarcococca hookeriana
Cochrane_2005_Alcohol.Alcohol_40_151 Acetylcholinesterase inhibitors for the treatment of Wernicke-Korsakoff syndrome--three further cases show response to donepezil
Cola_2005_J.Comp.Neurol_484_299 Neurochemical organization of chimpanzee inferior pulvinar complex
Collombet_2005_Neurotoxicol_26_89 Effect of soman poisoning on populations of bone marrow and peripheral blood cells in mice
Cometa_2005_Toxicology_206_125 In vitro inhibitory effect of aflatoxin B1 on acetylcholinesterase activity in mouse brain
Connelly_2005_Dement.Geriatr.Cogn.Disord_19_11 Current smoking and response to cholinesterase inhibitor therapy in Alzheimer's disease
Connelly_2005_J.Neurol.Neurosurg.Psychiatry_76_320 Predicting the outcome of cholinesterase inhibitor treatment in Alzheimer's disease
Converti_2005_Appl.Microbiol.Biotechnol_67_637 Synthesis of ethyl phenylacetate by lyophilized mycelium of Aspergillus oryzae
Cook_2005_Am.J.Med.Genet.B.Neuropsychiatr.Genet_132B_5 Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study
Cortes_2005_J.Nutr.Health.Aging_9_86 Recent data on the natural history of Alzheimer's disease: results from the REAL.FR Study
Costa_2005_Clin.Chim.Acta_352_37 Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity
Costa_2005_Biochem.Pharmacol_69_541 Modulation of paraoxonase (PON1) activity
Cousin_2005_Bioessays_27_189 Are there non-catalytic functions of acetylcholinesterases? Lessons from mutant animal models
Craparo_2005_Ultrasound.Obstet.Gynecol_25_144 The effects of serial intravascular transfusions in ascitic\/hydropic RhD-alloimmunized fetuses
Cui_2005_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_22_22 [Single nucleotide polymorphisms of genes associated with high density lipoprotein metabolism in Chinese population]
Dabisch_2005_Toxicol.Sci_85_1041 Miotic tolerance to sarin vapor exposure: role of the sympathetic and parasympathetic nervous systems
Darvesh_2005_Bioorg.Med.Chem_13_211 Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives
Das_2005_Chemosphere_58_579 A comparative study on the dissipation and microbial metabolism of organophosphate and carbamate insecticides in orchaqualf and fluvaquent soils of West Bengal
Das_2005_Prostaglandins.Leukot.Essent.Fatty.Acids_72_173 Long-chain polyunsaturated fatty acids, endothelial lipase and atherosclerosis
Dawson_2005_Rheumatology.(Oxford)_44_449 Hydroxychloroquine therapy in patients with primary Sjogren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase
De Jager_2005_J.Intern.Med_257_100 Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial
de la Torre_2005_Chemosphere_59_577 Biomarkers of a native fish species (Cnesterodon decemmaculatus) application to the water toxicity assessment of a peri-urban polluted river of Argentina
De Pedro_2005_Bioelectromagnetics_26_20 Pulsed electromagnetic fields induce peripheral nerve regeneration and endplate enzymatic changes
Decombel_2005_Arch.Insect.Biochem.Physiol_58_145 Action of 24-epibrassinolide on a cell line of the beet armyworm, Spodoptera exigua
Del_2005_Anal.Bioanal.Chem_381_1367 Determining pirimiphos-methyl in durum wheat samples using an acetylcholinesterase inhibition assay
Delwing_2005_Amino.Acids_28_305 Effect of hyperprolinemia on acetylcholinesterase and butyrylcholinesterase activities in rat
Devier_2005_J.Environ.Monit_7_224 One-year monitoring survey of organic compounds (PAHs, PCBs, TBT), heavy metals and biomarkers in blue mussels from the Arcachon Bay, France
D'Intino_2005_Proc.Natl.Acad.Sci.U.S.A_102_3070 Cognitive deficit associated with cholinergic and nerve growth factor down-regulation in experimental allergic encephalomyelitis in rats
Dong_2005_Psychopharmacology.(Berl)_181_145 Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer's disease
Dori_2005_Cereb.Cortex_15_419 Functional manipulations of acetylcholinesterase splice variants highlight alternative splicing contributions to murine neocortical development
Dorronsoro_2005_Arch.Pharm.(Weinheim)_338_18 Synthesis and biological evaluation of tacrine-thiadiazolidinone hybrids as dual acetylcholinesterase inhibitors
Du_2005_AJR.Am.J.Roentgenol_184_658 MRI of fat distribution in a mouse model of lysosomal acid lipase deficiency
Ebdrup_2005_Bioorg.Med.Chem_13_2305 Structure-activity relationship for aryl and heteroaryl boronic acid inhibitors of hormone-sensitive lipase
Engenheiro_2005_Environ.Toxicol.Chem_24_603 Influence of dimethoate on acetylcholinesterase activity and locomotor function in terrestrial isopods
Enoksson_2005_J.Clin.Endocrinol.Metab_90_1189 Marked reutilization of free fatty acids during activated lipolysis in human skeletal muscle
Espinoza-Navarro_2005_Asian.J.Androl_7_97 Effect of malathion on the male reproductive organs of earthworms, Eisenia foetida
Falasca_2005_J.Biol.Chem_280_878 Determinants of the t peptide involved in folding, degradation, and secretion of acetylcholinesterase
Farias_2005_Neurobiol.Dis_18_176 The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from beta-amyloid neurotoxicity by acting on Wnt signaling components
Farlow_2005_BMC.Geriatr_5_3 Rivastigmine: an open-label, observational study of safety and effectiveness in treating patients with Alzheimer's disease for up to 5 years
Fendri_2005_Chirality_17_57 Kinetic properties of turkey pancreatic lipase: a comparative study with emulsified tributyrin and monomolecular dicaprin
Fickers_2005_J.Biotechnol_115_379 Selection of new over-producing derivatives for the improvement of extracellular lipase production by the non-conventional yeast Yarrowia lipolytica
Fillion_2005_J.Org.Chem_70_1316 Meldrum's acids as acylating agents in the catalytic intramolecular Friedel-Crafts reaction
Fischer_2005_Arch.Biochem.Biophys_434_108 Lipsome-formulated enzymes for organophosphate scavenging: butyrylcholinesterase and Demeton-S
Flomenbom_2005_Proc.Natl.Acad.Sci.U.S.A_102_2368 Stretched exponential decay and correlations in the catalytic activity of fluctuating single lipase molecules
Foresti_2005_Anal.Bioanal.Chem_381_1408 Frequent analytical\/experimental problems in lipase-mediated synthesis in solvent-free systems and how to avoid them
Foster_2005_Bull.Entomol.Res_95_37 Reduced response of insecticide-resistant aphids and attraction of parasitoids to aphid alarm pheromone\; a potential fitness trade-off
Francis_2005_Trends.Pharmacol.Sci_26_104 A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease?
Freudenreich_2005_Psychopharmacology.(Berl)_181_358 Added donepezil for stable schizophrenia: a double-blind, placebo-controlled trial
Fry_2005_Genome.Res_15_403 From genome to venome: molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body proteins
Fukuda_2005_Rinsho.Byori_53_26 [Development of analysis of drugs and toxic substances that can play an immediate role in emergency medical service: what is to be analyzed?]
Fukuse_2005_Chest_127_886 Importance of a comprehensive geriatric assessment in prediction of complications following thoracic surgery in elderly patients
Fukushima_2005_Braz.J.Med.Biol.Res_38_367 Ectopic development of skeletal muscle induced by subcutaneous transplant of rat satellite cells
Gacko_2005_Med.Sci.Monit_11_CR211 Activity of enzymes with different subcellular localization in the blood plasma of patients with aortic aneurysm
Garcia_2005_Appl.Biochem.Biotechnol_120_81 Relative effectiveness of pretreatments on performance of Rhizomucor miehei lipase in nonpolar reaction media
Garcia-Alloza_2005_Neuropsychologia_43_442 Cholinergic-serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer's disease
Gatke_2005_Anesthesiology_102_503 Response to mivacurium in patients carrying the k variant in the butyrylcholinesterase gene
Gauster_2005_J.Lipid.Res_46_977 Endothelial lipase is inactivated upon cleavage by the members of the proprotein convertase family
Gauthier_2005_Am.J.Med.Genet.B.Neuropsychiatr.Genet_132B_74 NLGN3\/NLGN4 gene mutations are not responsible for autism in the Quebec population
Geerts_2005_Brain.Res.Bull_64_519 Indicators of neuroprotection with galantamine
Geerts_2005_Brain.Res_1033_186 Brain levels and acetylcholinesterase inhibition with galantamine and donepezil in rats, mice, and rabbits
Geier_2005_J.Cell.Physiol_204_687 Development and resolution of experimental colitis in mice with targeted deletion of dipeptidyl peptidase IV
Ghorbel_2005_Physiol.Genomics_22_93 Profile of changes in gene expression in cultured hippocampal neurones evoked by the GABAB receptor agonist baclofen
Gil-Bea_2005_Neurosci.Lett_375_37 Evaluation of cholinergic markers in Alzheimer's disease and in a model of cholinergic deficit
Giliani_2005_Planta.Med_71_120 Presence of antispasmodic, antidiarrheal, antisecretory, calcium antagonist and acetylcholinesterase inhibitory steroidal alkaloids in Sarcococca saligna
Gill_2005_Arch.Environ.Contam.Toxicol_48_118 Effects of azinphos-methyl on cholinergic responses and general health in zebra finches (Taeniopygia guttata) after previous treatment with p,p'-DDE
Gillette-Guyonnet_2005_J.Nutr.Health.Aging_9_69 Long-term cholinergic treatment is not associated with greater risk of weight loss during Alzheimer's disease: data from the French REAL.FR cohort
Godoy_2005_Chembiochem_6_395 Kinetics study of Bungarus fasciatus venom acetylcholinesterase immobilised on a Langmuir-Blodgett proteo-glycolipidic bilayer
Gorrell_2005_Clin.Sci.(Lond)_108_277 Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
Gralewicz_2005_Neurotoxicol_26_159 Pretreatment with footshock alters some effects of subsequent organophosphate exposure
Gray_2005_J.Pharmacol.Toxicol.Methods_51_41 Evaluation of the mouse prostate as a suitable model for the study of human prostate function
Gu_2005_Exp.Neurol_192_89 Survival, regeneration and functional recovery of motoneurons after delayed reimplantation of avulsed spinal root in adult rat
Guerrero_2005_Curr.Med.Chem_12_461 Biorational approaches for insect control by enzymatic inhibition
Gul_2005_Chemosphere_59_163 Investigation of acute toxicity of chlorpyrifos-methyl on Nile tilapia (Oreochromis niloticus L.) larvae
Gupta_2005_Appl.Microbiol.Biotechnol_67_648 Single-step purification of lipase from Burkholderia multivorans using polypropylene matrix
Hamamoto_2005_J.Gastroenterol.Hepatol_20_204 Changes in serum lipid concentrations in patients with chronic hepatitis C virus positive hepatitis responsive or non-responsive to interferon therapy
Hang_2005_Am.J.Respir.Crit.Care.Med_171_165 Microsomal epoxide hydrolase, endotoxin, and lung function decline in cotton textile workers
Hennebold_2005_Biol.Reprod_72_968 Identification and characterization of an ovary-selective isoform of epoxide hydrolase
Herholz_2005_J.Neurol.Neurosurg.Psychiatry_76_305 Action of cholinesterase inhibitors in patients' brains
Herrera_2005_Anal.Bioanal.Chem_381_695 Determination of pesticides and PCBs in honey by solid-phase extraction cleanup followed by gas chromatography with electron-capture and nitrogen-phosphorus detection
Hopkins_2005_Environ.Pollut_133_531 Differential swimming performance of two natricine snakes exposed to a cholinesterase-inhibiting pesticide
Hormazabal_2005_Z.Naturforsch.C_60_11 Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum
Houze_2005_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_814_149 Measurement of serum pralidoxime methylsulfate (Contrathion) by high-performance liquid chromatography with electrochemical detection
Huang_2005_Anal.Chem_77_1920 Characteristics of trapping various organophosphorus pesticides with a ferritin reactor of shark liver (Sphyrna zygaena)
Huang_2005_Cancer.Epidemiol.Biomarkers.Prev_14_152 Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma
Huang_2005_Cell.Cycle_4_140 Novel assay utilizing fluorochrome-tagged physostigmine (Ph-F) to in situ detect active acetylcholinesterase (AChE) induced during apoptosis
Hubatsch_2005_Antimicrob.Agents.Chemother_49_1087 Orally active antiviral tripeptide glycyl-prolyl-glycinamide is activated by CD26 (dipeptidyl peptidase IV) before transport across the intestinal epithelium
Hussain_2005_J.Coll.Physicians.Surg.Pak_15_100 Organophosphorus insecticide poisoning: management in surgical intensive care unit
Ichikawa_2005_Atherosclerosis_179_87 Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits
Ikonomovic_2005_Arch.Neurol_62_425 Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease
Inestrosa_2005_Neurobiol.Aging_26_1023 Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu
Inestrosa_2005_Subcell.Biochem_38_299 Acetylcholinesterase interaction with Alzheimer amyloid beta
Isetun_2005_Analyst_130_94 Dynamic field sampling of airborne organophosphate triesters using solid-phase microextraction under equilibrium and non-equilibrium conditions
Ishii_2005_Front.Biosci_10_887 Functional protein-protein interaction of drug metabolizing enzymes
Islam_2005_Life.Sci_76_1239 Engineered beta-cells secreting dipeptidyl peptidase IV-resistant glucagon-like peptide-1 show enhanced glucose-responsiveness
Isoda_2005_Environ.Sci_12_9 Effects of organophosphorous pesticides used in china on various mammalian cells
Jahangiri_2005_J.Lipid.Res_46_896 Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I
Jin_2005_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_22_27 [Study on differentially expressed gene of the liver of treble fatty metabolism genes mutant mice using cDNA microarray]
Johnson_2005_Eur.J.Pharmacol_506_209 The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release
Juel_2005_Curr.Treat.Options.Neurol_7_3 Autoimmune Myasthenia Gravis: Recommendations for Treatment and Immunologic Modulation
Jundt_2005_Neurourol.Urodyn_24_44 Is the histomorphological concept of the female pelvic floor and its changes due to age and vaginal delivery correct?
Karaman_2005_Dement.Geriatr.Cogn.Disord_19_51 A 12-month study of the efficacy of rivastigmine in patients with advanced moderate Alzheimer's disease
Keilhoff_2005_Muscle.Nerve_31_221 Successful intramuscular neurotization is dependent on the denervation period. A histomorphological study of the gracilis muscle in rats
Kendrick_2005_J.Perianesth.Nurs_20_7 Prolonged paralysis related to mivacurium: a case study
Khan_2005_Arch.Pharm.Res_28_172 Butyrylcholinesterase inhibitory guaianolides from Amberboa ramosa
Kim_2005_Protein.Expr.Purif_39_124 Purification, refolding, and characterization of recombinant Pseudomonas fluorescens lipase
Kmietowicz_2005_BMJ_330_495 NICE proposes to withdraw Alzheimer's drugs from NHS
Koch_2005_Ernst.Schering.Res.Found.Workshop__1 Protein domain fold similarity and natural product structure as guiding principles for compound library design
Koffel_2005_Mol.Cell.Biol_25_1655 The Saccharomyces cerevisiae YLL012\/YEH1, YLR020\/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis
Koike_2005_Cardiovasc.Res_65_524 Enhanced aortic atherosclerosis in transgenic Watanabe heritable hyperlipidemic rabbits expressing lipoprotein lipase
Kotelevets_2005_Life.Sci_76_2211 Cholinesterase activity in human pulmonary arteries and veins: correlation with mRNA levels
Kratky_2005_J.Clin.Invest_115_161 Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue
Kruschinski_2005_Clin.Exp.Immunol_139_17 CD26 (dipeptidyl-peptidase IV)-dependent recruitment of T cells in a rat asthma model
Kunzle_2005_Brain.Res_1034_90 The striatum in the hedgehog tenrec: histochemical organization and cortical afferents
Lachenmeier_2005_Rapid.Commun.Mass.Spectrom_19_108 Application of tandem mass spectrometry combined with gas chromatography to the routine analysis of ethyl carbamate in stone-fruit spirits
Lane_2005_J.Lipid.Res_46_949 Lipid homeostasis and apolipoprotein E in the development and progression of Alzheimer's disease
Lavenu_2005_Dement.Geriatr.Cogn.Disord_19_37 Perception of emotion on faces in frontotemporal dementia and Alzheimer's disease: a longitudinal study
Law_2005_Biosens.Bioelectron_20_1914 Sonochemically fabricated acetylcholinesterase micro-electrode arrays within a flow injection analyser for the determination of organophosphate pesticides
Layer_2005_Clin.Gastroenterol.Hepatol_3_25 Gastric lipase and pancreatic exocrine insufficiency
Layish_2005_Isr.Med.Assoc.J_7_182 Pharmacologic prophylaxis against nerve agent poisoning
Lee_2005_Planta.Med_71_7 Anti-acetylcholinesterase and anti-amnesic activities of a pregnane glycoside, cynatroside B, from Cynanchum atratum
Lee_2005_Biotechnol.Bioeng_90_223 Display of lipase on the cell surface of Escherichia coli using OprF as an anchor and its application to enantioselective resolution in organic solvent
Lei_2005_J.Agric.Food.Chem_53_524 Direct determination of p-nitrophenyl substituent organophosphorus nerve agents using a recombinant Pseudomonas putida JS444-modified Clark oxygen electrode
Lein_2005_Toxicol.Sci_83_166 Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition
Lentz_2005_Am.J.Pharmacogenomics_5_21 Pharmacogenomics of fluorouracil, irinotecan, and oxaliplatin in hepatic metastases of colorectal cancer: clinical implications
Leon_2005_Bioorg.Med.Chem_13_1167 Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues
Letant_2005_Chem.Commun.(Camb)__851 Hydrolysis of acetylcholinesterase inhibitors--organophosphorus acid anhydrolase enzyme immobilization on photoluminescent porous silicon platforms
Li_2005_Chem.Commun.(Camb)__130 Stereochemistry of the reaction catalysed by 2-hydroxy-6-keto-6-phenyl-hexa-2,4-dienoic acid 5,6-hydrolase (BphD)
Li_2005_J.Biol.Chem_280_18179 Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors
Liang_2005_Beijing.Da.Xue.Xue.Bao_37_85 [Associations of genetic polymorphisms in the EPHX1 gene and the GSTT1 gene with low birth weight in neonates]
Liang_2005_Mol.Pharmacol_67_220 Alternative promoters determine tissue-specific expression profiles of the human microsomal epoxide hydrolase gene (EPHX1)
Lin_2005_Bioorg.Med.Chem.Lett_15_951 A rate determining step change in the pre-steady state of acetylcholinesterase inhibitions by 1,n-alkane-di-N-butylcarbamates
Lindegaard_2005_J.Lipid.Res_46_439 Expression of the endothelial lipase gene in murine embryos and reproductive organs
Liu_2005_Zhonghua.Yi.Xue.Yi.Chuan.Xue.Za.Zhi_22_151 [The association of S447X and Hind III polymorphism in the lipoprotein lipase gene with dyslipidemia of the metabolic syndrome in patients with essential hypertension]
Liu_2005_Metabolism_54_132 High lipoprotein lipase activity increases insulin sensitivity in transgenic rabbits
Liu_2005_Dement.Geriatr.Cogn.Disord_19_345 Cholinesterase inhibitor affects the amyloid precursor protein isoforms in patients with Alzheimer's disease
Liu_2005_Proc.Natl.Acad.Sci.U.S.A_102_701 Enantioselectivity in environmental safety of current chiral insecticides
London_2005_Am.J.Ind.Med_47_308 Suicide and exposure to organophosphate insecticides: cause or effect?
Lopez_2005_J.Am.Geriatr.Soc_53_83 Alteration of a clinically meaningful outcome in the natural history of Alzheimer's disease by cholinesterase inhibition
Lopez-Pousa_2005_Dement.Geriatr.Cogn.Disord_19_189 Differential efficacy of treatment with acetylcholinesterase inhibitors in patients with mild and moderate Alzheimer's disease over a 6-month period
Lu_2005_J.Toxicol.Environ.Health.A_68_209 The presence of dialkylphosphates in fresh fruit juices: implication for organophosphorus pesticide exposure and risk assessments
Lydy_2005_Arch.Environ.Contam.Toxicol_48_49 Toxicity assessment of pesticide mixtures typical of the Sacramento-San Joaquin Delta using Chironomus tentans
Maeda_2005_J.Nutr.Biochem_16_121 Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach
Makrides_2005_JOP_6_166 Methomyl-induced severe acute pancreatitis: possible etiological association
Manjuck_2005_Chest_127_246 Clinical significance of increased lipase levels on admission to the ICU
Manojkumar_2005_J.Comput.Chem_26_606 Theoretical insights into the mechanism of acetylcholinesterase-catalyzed acylation of acetylcholine
Marangoni_2005_G.Ital.Nefrol_22 Suppl 31_S156 [Molecular Adsorbent Recirculating System in liver function replacement therapy]
Maresh_2005_Physiol.Genomics_21_308 Tobacco smoke dysregulates endothelial vasoregulatory transcripts in vivo
Martin-Hidalgo_2005_J.Lipid.Res_46_658 Expression, activity, and localization of hormone-sensitive lipase in rat mammary gland during pregnancy and lactation
Mayor_2005_BMJ_330_276 Regulatory authorities review use of galantamine in mild cognitive impairment
McIntosh_2005_Regul.Pept_128_159 Dipeptidyl peptidase IV inhibitors: how do they work as new antidiabetic agents?
Mest_2005_Diabetologia_48_616 Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes
Milatovic_2005_Toxicology_208_13 Carbofuran-induced oxidative stress in slow and fast skeletal muscles: prevention by memantine and atropine
Misra_2005_Toxicol.In.Vitro_19_433 Effect of UVB radiation on human erythrocytes in vitro
Miyazawa_2005_J.Agric.Food.Chem_53_1765 Inhibition of acetylcholinesterase activity by bicyclic monoterpenoids
Mokry_2005_Physiol.Res_54_453 Reactivity of urinary bladder smooth muscle in guinea pigs to acetylcholine and carbachol--participation of acetylcholinesterase
Moore_2005_Pediatr.Surg.Int_21_255 Acetylcholinesterase in Hirschsprung's disease
Morishita_2005_J.Int.Med.Res_33_84 Effect of carboxylesterase inhibition on the anti-tumour effects of irinotecan
Morisseau_2005_Annu.Rev.Pharmacol.Toxicol_45_311 Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles
Moriya_2005_Forensic.Sci.Int_149_167 A fatal poisoning caused by methomyl and nicotine
Muhlig-Versen_2005_J.Neurosci_25_2865 Loss of Swiss cheese\/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila
Murphy_2005_J.Vet.Diagn.Invest_17_74 Whole-blood and plasma cholinesterase levels in normal koi (Cyprinus carpio)
Musser_2005_Pest.Manag.Sci_61_508 The influence of post-exposure temperature on the toxicity of insecticides to Ostrinia nubilalis (Lepidoptera: Crambidae)
Newman_2005_Prog.Lipid.Res_44_1 Epoxide hydrolases: their roles and interactions with lipid metabolism
Nierman_2005_Neth.J.Med_63_14 Gene therapy for genetic lipoprotein lipase deficiency: from promise to practice
Niho_2005_Proc.Natl.Acad.Sci.U.S.A_102_2970 Concurrent suppression of hyperlipidemia and intestinal polyp formation by NO-1886, increasing lipoprotein lipase activity in Min mice
Nizri_2005_Neurosci.Lett_376_46 Bifunctional compounds eliciting both anti-inflammatory and cholinergic activity as potential drugs for neuroinflammatory impairments
Noureddini_2005_Bioresour.Technol_96_769 Immobilized Pseudomonas cepacia lipase for biodiesel fuel production from soybean oil
Obermayr_2005_Exp.Gerontol_40_157 The age-related down-regulation of the growth hormone\/insulin-like growth factor-1 axis in the elderly male is reversed considerably by donepezil, a drug for Alzheimer's disease
Okahashi_2005_Toxicology_206_17 Lack of evidence for endocrine disrupting effects in rats exposed to fenitrothion in utero and from weaning to maturation
Oosterhoff_2005_Br.J.Cancer_92_882 Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11
Oosterhoff_2005_Gene.Ther_12_1011 Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24
Osten_2005_Environ.Toxicol.Chem_24_313 Black-bellied whistling duck (Dendrocygna autumnalis) brain cholinesterase characterization and diagnosis of anticholinesterase pesticide exposure in wild populations from Mexico
Pallares_2005_Proc.Natl.Acad.Sci.U.S.A_102_3978 Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin
Pappan_2005_J.Biol.Chem_280_9023 Pancreatic beta-cell lipoprotein lipase independently regulates islet glucose metabolism and normal insulin secretion
Park_2005_Int.J.Mol.Med_15_443 Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD
Parran_2005_Neurotoxicol_26_77 Chlorpyrifos alters functional integrity and structure of an in vitro BBB model: co-cultures of bovine endothelial cells and neonatal rat astrocytes
Passmore_2005_J.Neurol.Sci_229-230_141 Cognitive, global, and functional benefits of donepezil in Alzheimer's disease and vascular dementia: results from large-scale clinical trials
Paulsson_2005_Mutat.Res_580_53 In vitro studies of the influence of glutathione transferases and epoxide hydrolase on the detoxification of acrylamide and glycidamide in blood
Perras_2005_Issues.Emerg.Health.Technol__1 Memantine for treatment of moderate to severe Alzheimer's disease
Petroianu_2005_Eur.J.Emerg.Med_12_102 Organophosphate poisoning: the lesser-known face of a toxidrome
Petroianu_2005_Anesth.Analg_100_382 Protective drugs in acute large-dose exposure to organophosphates: a comparison of metoclopramide and tiapride with pralidoxime in rats
Pic_2005_AANA.J_73_37 Novel pharmacological approaches for the antagonism of neuromuscular blockade
Pighin_2005_J.Appl.Physiol.(1985)_98_1064 Role of lipids in the early developmental stages of experimental immune diabetes induced by multiple low-dose streptozotocin
Pina-Guzman_2005_Toxicol.Appl.Pharmacol_202_189 Diazinon alters sperm chromatin structure in mice by phosphorylating nuclear protamines
Pithayanukul_2005_J.Ethnopharmacol_97_527 Inhibition of Naja kaouthia venom activities by plant polyphenols
Porter_2005_Curr.Treat.Options.Neurol_7_79 Ocular Myasthenia Gravis
Powers_2005_Surgery_137_66 Hypertonic resuscitation of hemorrhagic shock prevents alveolar macrophage activation by preventing systemic oxidative stress due to gut ischemia\/reperfusion
Prickaerts_2005_Psychopharmacology.(Berl)_177_381 Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation
Pulinilkunnil_2005_Am.J.Physiol.Heart.Circ.Physiol_288_H2802 Lysophosphatidic acid-mediated augmentation of cardiomyocyte lipoprotein lipase involves actin cytoskeleton reorganization
Quyen_2005_Protein.Expr.Purif_39_97 High-level heterologous expression and properties of a novel lipase from Ralstonia sp. M1
Rabitto_2005_Ecotoxicol.Environ.Saf_60_147 Effects of dietary Pb(II) and tributyltin on neotropical fish, Hoplias malabaricus: histopathological and biochemical findings
Rader_2005_Neth.J.Med_63_2 Gene therapy for genetic lipid disorders: lipoprotein lipase deficiency as a paradigm
Ragheb_2005_Biomaterials_26_1653 Highly active, lipase silicone elastomers
Ramachander_2005_FEMS.Microbiol.Lett_242_13 PHB synthase from Streptomyces aureofaciens NRRL 2209
Rao_2005_J.Pharm.Biomed.Anal_37_57 A stability indicating LC method for rivastigmine hydrogen tartrate
Rayyan_2005_J.Paediatr.Child.Health_41_152 Neonatal cholinesterase inhibitor poisoning: materno-fetal exchange of pesticide
Reale_2005_Exp.Gerontol_40_165 Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients
Regan_2005_Int.J.Geriatr.Psychiatry_20_261 Relationship of exercise and other risk factors to depression of Alzheimer's disease: the LASER-AD study
Richardson_2005_Toxicol.Sci_84_352 Effects of repeated oral postnatal exposure to chlorpyrifos on cholinergic neurochemistry in developing rats
Rikkert_2005_Eur.J.Neurol_12_212 The practice of obtaining approval from medical research ethics committees: a comparison within 12 European countries for a descriptive study on acetylcholinesterase inhibitors in Alzheimer's dementia
Ringelstein_2005_Curr.Opin.Neurol_18_179 Cerebral small vessel diseases: cerebral microangiopathies
Rissato_2005_J.Agric.Food.Chem_53_62 Multiresidue analysis of pesticides in soil by supercritical fluid extraction\/gas chromatography with electron-capture detection and confirmation by gas chromatography-mass spectrometry
Roberts_2005_Cochrane.Database.Syst.Rev__CD004897 Alkalinisation for organophosphorus pesticide poisoning
Roldan-Tapia_2005_Neurotoxicol.Teratol_27_259 Neuropsychological effects of long-term exposure to organophosphate pesticides
Roman_2005_Curr.Psychiatry.Rep_7_18 Cholinergic dysfunction in vascular dementia
Roy_2005_Brain.Res.Dev.Brain.Res_155_71 Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats
Ruge_2005_Eur.J.Clin.Invest_35_194 Tissue-specific regulation of lipoprotein lipase in humans: effects of fasting
Ruiz_2005_Lett.Appl.Microbiol_40_218 Isolation of lipid- and polysaccharide-degrading micro-organisms from subtropical forest soil, and analysis of lipolytic strain Bacillus sp. CR-179
Sabolek_2005_Behav.Brain.Res_158_1 Intraseptal tacrine-induced disruptions of spatial memory performance
Sagiroglu_2005_Prep.Biochem.Biotechnol_35_37 Sunflower seed lipase: extraction, purification, and characterization
Sakai_2005_J.Org.Chem_70_1369 Lipase-catalyzed resolution of (2R*,3S*)- and (2R*,3R*)-3-methyl-3-phenyl-2-aziridinemethanol at low temperatures and determination of the absolute configurations of the four stereoisomers
Salah_2005_J.Ethnopharmacol_97_145 Screening of traditionally used Lebanese herbs for neurological activities
Sandahl_2005_Environ.Toxicol.Chem_24_136 Comparative thresholds for acetylcholinesterase inhibition and behavioral impairment in coho salmon exposed to chlorpyrifos
Sara_2005_J.Neurosci_25_260 Selective capability of SynCAM and neuroligin for functional synapse assembly
Segev_2005_J.Org.Chem_70_309 Probing the molecular interaction of chymotrypsin with organophosphorus compounds by 31P diffusion NMR in aqueous solutions
Sellers_2005_FASEB.J_19_626 Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat
Sembulingam_2005_J.Ethnopharmacol_96_477 Effect of Ocimum sanctum Linn on the changes in central cholinergic system induced by acute noise stress
Serrano_2005_Chest_127_7 Increased lipase plasma levels in ICU patients: when are they critical?
Servatius_2005_Neuropsychopharmacology_30_1483 Mild interoceptive stressors affect learning and reactivity to contextual cues: toward understanding the development of unexplained illnesses
Shanks_2005_Am.J.Geriatr.Psychiatry_13_170\; author reply 170 Conventional trial designs offer limited clinical understanding of cholinesterase-inhibitor treatment effects in Alzheimer disease
Shao_2005_Bioorg.Med.Chem_13_869 Evaluation of 18F-labeled acetylcholinesterase substrates as PET radiotracers
Shao_2005_Neurosci_130_1069 Cholinergic neurotransmission in the preBotzinger Complex modulates excitability of inspiratory neurons and regulates respiratory rhythm
Sharma_2005_Toxicology_206_49 Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental rats
Sheridan_2005_J.R.Soc.Med_98_114 Nicotinic antagonists in the treatment of nerve agent intoxication
Shin_2005_Amino.Acids_28_63 Identification and characterisation of soluble epoxide hydrolase in mouse brain by a robust protein biochemical method
Shitoh_2005_Int.J.Colorectal.Dis_20_77 Successful treatment of nonocclusive mesenteric ischemia after organophosphate poisoning
Sias_2005_Biochim.Biophys.Acta_1686_169 Cloning and seasonal secretion of the pancreatic lipase-related protein 2 present in goat seminal plasma
Singer_2005_Nervenarzt_76_1127 [Nightmares in patients with Alzheimer's disease caused by donepezil. Therapeutic effect depends on the time of intake]
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Smith_2005_Proc.Natl.Acad.Sci.U.S.A_102_2186 Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor
Snodgrass_2005_J.Econ.Entomol_98_177 Toxicity of insecticides in a glass-vial bioassay to adult brown, green, and southern green stink bugs (Heteroptera: Pentatomidae)
Sonkusare_2005_Pharmacol.Res_51_1 Dementia of Alzheimer's disease and other neurodegenerative disorders--memantine, a new hope
Soriano_2005_J.Am.Chem.Soc_127_1946 Dynamic and electrostatic effects in enzymatic processes. An analysis of the nucleophilic substitution reaction in haloalkane dehalogenase
de Souza_2005_Am.J.Phys.Anthropol_126_329 Possible influence of BCHE locus of butyrylcholinesterase on stature and body mass index
Spowart-Manning_2005_Behav.Brain.Res_156_269 Spatial discrimination deficits by excitotoxic lesions in the Morris water escape task
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Stuchbury_2005_J.Neural.Transm.(Vienna)_112_429 Alzheimer's associated inflammation, potential drug targets and future therapies
Studzinski_2005_Prog.Neuropsychopharmacol.Biol.Psychiatry_29_489 The canine model of human cognitive aging and dementia: pharmacological validity of the model for assessment of human cognitive-enhancing drugs
Suarez_2005_Proteins_59_104 Molecular dynamics simulations of human butyrylcholinesterase
Sugaroon_2005_Trop.Doct_35_55 Low level of serum cholinesterase among a sample of Thai agricultural workers
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Temerowski_2005_Neurotoxicol.Teratol_27_279 Absence of long-term behavioral effects after sub-chronic administration of low doses of methamidophos in male and female rats
Tenovuo_2005_Prog.Neuropsychopharmacol.Biol.Psychiatry_29_61 Central acetylcholinesterase inhibitors in the treatment of chronic traumatic brain injury-clinical experience in 111 patients
Thorne_2005_Clin.Nutr_24_66 Influence of trauma on plasma elimination of exogenous fat and on lipoprotein lipase activity and mass
Tsai_2005_Biosens.Bioelectron_20_1796 Simultaneous determination of pH, urea, acetylcholine and heavy metals using array-based enzymatic optical biosensor
Twu_2005_J.Agric.Food.Chem_53_1012 Optimization of lipase-catalyzed synthesis of octyl hydroxyphenylpropionate by response surface methodology
Uckun_2005_Arzneimittelforschung_55_50 Antileukemic activity and cellular metabolism of the aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07)
Unger_2005_J.Neural.Transm.(Vienna)_112_255 Effect of memantine on the alpha 7 neuronal nicotinic receptors, synaptophysin- and low molecular weight MAP-2 levels in the brain of transgenic mice over-expressing human acetylcholinesterase
Van Dam_2005_Psychopharmacology.(Berl)_180_177 Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model
Van Dam_2005_Neurochem.Int_46_409 Analysis of cholinergic markers, biogenic amines, and amino acids in the CNS of two APP overexpression mouse models
van der Staay_2005_Behav.Brain.Res_156_1 Effects of the cholinesterase inhibitors donepezil and metrifonate on scopolamine-induced impairments in the spatial cone field orientation task in rats
van Reekum_2005_J.Neuropsychiatry.Clin.Neurosci_17_7 Apathy: why care?
Vanacore_2005_Acta.Neurol.Scand_111_199 Pisa syndrome in a cohort of Alzheimer's disease patients
Venkateswara_2005_Pest.Manag.Sci_61_417 Effect of chlorpyrifos and monocrotophos on locomotor behaviour and acetylcholinesterase activity of subterranean termites, Odontotermes obesus
Venneri_2005_Neuroreport_16_107 Empirical evidence of neuroprotection by dual cholinesterase inhibition in Alzheimer's disease
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von Bernhardi_2005_Dement.Geriatr.Cogn.Disord_19_204 Blood cells cholinesterase activity in early stage Alzheimer's disease and vascular dementia
Vukova_2005_Med.Sci.Monit_11_BR50 Intensity-dependent effects of microwave electromagnetic fields on acetylcholinesterase activity and protein conformation in frog skeletal muscles
Walker_2005_Anal.Chem_77_1596 Acetylcholinesterase-based organophosphate nerve agent sensing photonic crystal
Wang_2005_Biochemistry_44_1953 Mutational analysis of the regulatory module of hormone-sensitive lipase
Wang_2005_J.Neurosci_25_343 Activity-dependent presynaptic regulation of quantal size at the mammalian neuromuscular junction in vivo
Warren_2005_Brain_128_239 Cholinergic systems in progressive supranuclear palsy
Watt_2005_Diabetologia_48_105 Hormone-sensitive lipase is reduced in the adipose tissue of patients with type 2 diabetes mellitus: influence of IL-6 infusion
White_2005_Biosens.Bioelectron_20_1977 Optical solid-state detection of organophosphates using organophosphorus hydrolase
Wisor_2005_Neurosci_131_375 Sleep and circadian abnormalities in a transgenic mouse model of Alzheimer's disease: a role for cholinergic transmission
Wu_2005_BMC.Cell.Biol_6_4 Extracellular degradation of lipoprotein lipase in rat adipose tissue
Wuilloud_2005_Electrophoresis_26_1598 The potential of inductively coupled plasma-mass spectrometric detection for capillary electrophoretic analysis of pesticides
Xu_2005_Biol.Pharm.Bull_28_490 Protective effects of Hippophae rhamnoides L. juice on lead-induced neurotoxicity in mice
Yamamoto_2005_Metabolism_54_67 Effects of diacylglycerol administration on serum triacylglycerol in a patient homozygous for complete lipoprotein lipase deletion
Yan_2005_Mol.Psychiatry_10_329 Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients
Ye_2005_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_817_187 Ion-pair reverse-phase high performance liquid chromatography method for determination of Huperzine-A in beagle dog serum
Yoo_2005_Bioorg.Med.Chem.Lett_15_353 Isoterreulactone A, a novel meroterpenoid with anti-acetylcholinesterase activity produced by Aspergillus terreus
Youdim_2005_J.Neurosci.Res_79_172 Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition
Young_2005_Neurotoxicol_26_199 Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates
Yu_2005_Eur.J.Pharmacol_508_15 Donepezil blocks voltage-gated ion channels in rat dissociated hippocampal neurons
Zacharova_2005_J.Intern.Med_257_185 The G-250A substitution in the promoter region of the hepatic lipase gene is associated with the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial
Zhang_2005_Biophys.J_88_1659 Tetrameric mouse acetylcholinesterase: continuum diffusion rate calculations by solving the steady-state Smoluchowski equation using finite element methods
Zhao_2005_Behav.Brain.Res_156_85 Effect of cholinergic medication, before and after focal photothrombotic ischemic cortical injury, on histological and functional outcome in aged and young adult rats
Zheng_2005_Proteins_59_1 Protein domain of unknown function DUF1023 is an alpha\/beta hydrolase
Zhou_2005_Arch.Insect.Biochem.Physiol_58_157 Immunological assessment of an insecticide resistance-associated esterase in the Western corn rootworm
Zivkovic_2005_Acta.Histochem_106_449 The effects of chronic stress on thymus innervation in the adult rat
Kelly-Hope_2005_Trans.R.Soc.Trop.Med.Hyg_99_751 Spatiotemporal distribution of insecticide resistance in Anopheles culicifacies and Anopheles subpictus in Sri Lanka
Lecomte_2005_Mol.Cell.Neurosci_28_303 Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia
Wei_2005_J.Med.Chem_48_1721 Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing beta2 subunits
Green_2005_Int.J.Radiat.Biol_81_869 An investigation of the effects of TETRA RF fields on intracellular calcium in neurones and cardiac myocytes
Harrison_2005_Eur.J.Pharmacol_518_123 Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus
Sheridan_2005_Eur.J.Pharmacol_511_99 Effects of seven drugs of abuse on action potential repolarisation in sheep cardiac Purkinje fibres
Alkondon_2005_J.Pharmacol.Exp.Ther_313_740 Nicotinic receptor subtypes in rat hippocampal slices are differentially sensitive to desensitization and early in vivo functional up-regulation by nicotine and to block by bupropion
Rassoulpour_2005_Neuropsychopharmacology_30_697 Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat
Toth_2005_Brain.Res.Bull_66_37 EEG effect of basal forebrain neuropeptide Y administration in urethane anaesthetized rats
Zaborszky_2005_Neurosci_136_697 Three-dimensional chemoarchitecture of the basal forebrain: spatially specific association of cholinergic and calcium binding protein-containing neurons
Chepkova_2005_Cell.Mol.Neurobiol_25_767 Long-lasting enhancement of corticostriatal transmission by taurine: role of dopamine and acetylcholine
Jabourian_2005_Eur.J.Neurosci_21_3301 Functional mu opioid receptors are expressed in cholinergic interneurons of the rat dorsal striatum: territorial specificity and diurnal variation
Grillner_2005_Trends.Neurosci_28_364 Mechanisms for selection of basic motor programs--roles for the striatum and pallidum
Nygard_2005_Brain.Res.Bull_65_149 Age-related changes in electrophysiological properties of the mouse suprachiasmatic nucleus in vitro
Kimpinski_2005_J.Nematol_37_473 Nematicides increase grain yields in spring wheat cultivars and suppress plant-parasitic and bacterial-feeding nematodes
Tsiropoulos_2005_J.AOAC.Int_88_1827 Liquid chromatographic determination of fosthiazate residues in environmental samples and application of the method to a fosthiazate field dissipation study
Arca_2005_J.Exp.Biol_208_3971 An updated catalogue of salivary gland transcripts in the adult female mosquito, Anopheles gambiae
Francischetti_2005_Insect.Biochem.Mol.Biol_35_1142 The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae)
Veiga_2005_Gene_355_11 A catalog for the transcripts from the venomous structures of the caterpillar Lonomia obliqua: identification of the proteins potentially involved in the coagulation disorder and hemorrhagic syndrome
Diaz-Lopez_2005_Exp.Cell.Res_307_91 Characterization of MDGA1, a novel human glycosylphosphatidylinositol-anchored protein localized in lipid rafts
Kang_2005_FEMS.Microbiol.Lett_253_323 Coaggregation ability of Weissella cibaria isolates with Fusobacterium nucleatum and their adhesiveness to epithelial cells
Cerasoli_2005_Chem.Biol.Interact_157-158_363 In vitro and in vivo characterization of recombinant human butyrylcholinesterase (Protexia) as a potential nerve agent bioscavenger
Johnson_2005_Immunol.Lett_96_121 Role of immunogen design in induction of soman-specific monoclonal antibodies
Lenz_2005_Chem.Biol.Interact_157-158_205 Protection against soman or VX poisoning by human butyrylcholinesterase in guinea pigs and cynomolgus monkeys
Gilham_2005_Mol.Biol.Cell_16_984 Triacylglycerol hydrolase is localized to the endoplasmic reticulum by an unusual retrieval sequence where it participates in VLDL assembly without utilizing VLDL lipids as substrates
Gilham_2005_Biochim.Biophys.Acta_1736_189 Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase
Wei_2005_Biochem.J_388_959 C\/EBPalpha activates the transcription of triacylglycerol hydrolase in 3T3-L1 adipocytes
Brandt_2005_Peptides_26_2536 Search for substrates for prolyl oligopeptidase in porcine brain
Van der Veken_2005_J.Med.Chem_48_1768 Fluoro-olefins as peptidomimetic inhibitors of dipeptidyl peptidases
Ulbricht_2005_Physiol.Rev_85_1271 Sodium channel inactivation: molecular determinants and modulation
Santer_2005_J.Inherit.Metab.Dis_28_137 Hyperchylomicronaemia due to lipoprotein lipase deficiency as a cause of false-positive newborn screening for biotinidase deficiency
Drogemuller_2005_J.Hered_96_735 Characterization of candidate genes for neuronal ceroid lipofuscinosis in dog
Kohan_2005_Clin.Biochem_38_492 Palmitoyl Protein Thioesterase1 (PPT1) and Tripeptidyl Peptidase-I (TPP-I) are expressed in the human saliva. A reliable and non-invasive source for the diagnosis of infantile (CLN1) and late infantile (CLN2) neuronal ceroid lipofuscinoses
Mole_2005_Neurogenetics_6_107 Correlations between genotype, ultrastructural morphology and clinical phenotype in the neuronal ceroid lipofuscinoses
Taschner_2005_Ned.Tijdschr.Geneeskd_149_300 [From gene to disease\; from CLN1, CLN2 and CLN3 to neuronal ceroid lipofuscinosis]
Deck_2005_Angew.Chem.Int.Ed.Engl_44_4975 Development and biological evaluation of acyl protein thioesterase 1 (APT1) inhibitors
Mashiba_2005_Circ.J_69_1466 Vasospastic angina and microvascular angina are differentially influenced by PON1 A632G polymorphism in the Japanese
Afach_2005_Biosci.Biotechnol.Biochem_69_833 Synthesis of D-allose fatty acid esters via lipase-catalyzed regioselective transesterification
Alcantara_2005_Clin.Chem.Lab.Med_43_285 Butyrylcholinesterase activity and metabolic syndrome in obese patients
Arsov_2005_Arch.Biochem.Biophys_437_78 Inhibition of erythrocyte acetylcholinesterase by n-butanol at high concentrations
Ashton_2005_Bioorg.Med.Chem.Lett_15_2253 Dipeptidyl peptidase IV inhibitors derived from beta-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole
Augustyns_2005_Curr.Med.Chem_12_971 The therapeutic potential of inhibitors of dipeptidyl peptidase IV (DPP IV) and related proline-specific dipeptidyl aminopeptidases
Avila-Gonzalez_2005_Biotechnol.Prog_21_338 Candida rugosa lipase-catalyzed intramolecular O- to N- transacylation of butyryl propranolol in the presence of cyclodextrins
Ballard_2005_Dement.Geriatr.Cogn.Disord_19_357 The k variant of the butyrylcholinesterase gene is associated with reduced phosphorylation of tau in dementia patients
Bellelli_2005_Aging.Clin.Exp.Res_17_54 Results of a multi-level therapeutic approach for Alzheimer's disease subjects in the real world (CRONOS project): a 36-week follow-up study
Birkhofer_2005_Fortschr.Neurol.Psychiatr_73_192 [Heart and brain -- the influence of psychiatric disorders and their therapy on the heart rate variability]
Bonelli_2005_Int.Clin.Psychopharmacol_20_145 The influence of psychotropic drugs on cerebral cell death: female neurovulnerability to antipsychotics
Bos_2005_Am.J.Clin.Nutr_81_911 Interactions of dietary fat intake and the hepatic lipase -480C-->T polymorphism in determining hepatic lipase activity: the Hoorn Study
Choudhary_2005_Bioorg.Med.Chem_13_1939 Microbial transformation of (-)-isolongifolol and butyrylcholinesterase inhibitory activity of transformed products
Craig_2005_Cochrane.Database.Syst.Rev__CD004744 Rivastigmine for vascular cognitive impairment
Cunha_2005_J.Environ.Monit_7_288 Sea-urchin (Paracentrotus lividus) glutathione S-transferases and cholinesterase activities as biomarkers of environmental contamination
de Freitas_2005_Eur.J.Pharm.Sci_25_67 A new sunscreen of the cinnamate class: synthesis and enzymatic hydrolysis evaluation of glyceryl esters of p-methoxycinnamic acid
de Melo Abreu_2005_Anal.Bioanal.Chem_382_498 Determination of ethyl carbamate in alcoholic beverages: an interlaboratory study to compare HPLC-FLD with GC-MS methods
Devi_2005_Bull.Environ.Contam.Toxicol_74_250 Cholinesterase activity in clam Meretrix casta: possible biomarker for organophosphate pesticide pollution
Drebber_2005_World.J.Gastroenterol_11_2364 Severe chronic diarrhea and weight loss in cholesteryl ester storage disease: a case report
Fontaine_2005_J.Med.Chem_48_2687 Anchor-GRIND: filling the gap between standard 3D QSAR and the GRid-INdependent descriptors
Gill_2005_Arch.Intern.Med_165_808 A prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs
Gomez_2005_J.Mol.Endocrinol_34_331 The -514 C\/T polymorphism in the hepatic lipase gene promoter is associated with insulin sensitivity in a healthy young population
Hanagasi_2005_Fundam.Clin.Pharmacol_19_133 Treatment of behavioural symptoms and dementia in Parkinson's disease
Happich_2005_Psychiatr.Prax_32_142 [Cost-effectiveness of galantamine in a german context]
Harada_2005_N.Engl.J.Med_352_1387\; author reply 1387 Rivastigmine for dementia associated with Parkinson's disease
Hashimoto_2005_Am.J.Psychiatry_162_676 Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer's disease?
Ho_2005_Biosystems_80_133 Computational multiple steady states for enzymatic esterification of ethanol and oleic acid in an isothermal CSTR
Holmes_2005_J.Neurol.Neurosurg.Psychiatry_76_640 Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation
Huang_2005_World.J.Gastroenterol_11_2603 Effects of long-term ethanol consumption on jejunal lipase and disaccharidase activities in male and female rats
Hui_2005_Diabetes.Metab.Res.Rev_21_313 Structure and function studies of glucagon-like peptide-1 (GLP-1): the designing of a novel pharmacological agent for the treatment of diabetes
Ishii_2005_Tohoku.J.Exp.Med_206_23 Liver fat content measured by magnetic resonance spectroscopy at 3.0 tesla independently correlates with plasminogen activator inhibitor-1 and body mass index in type 2 diabetic subjects
Jain_2005_Anal.Bioanal.Chem_381_1480 A microwave-assisted microassay for lipases
Jeong_2005_World.J.Gastroenterol_11_1965 Amylase level in extrahepatic bile duct in adult patients with choledochal cyst plus anomalous pancreatico-biliary ductal union
Kodera_2005_J.Rheumatol_32_629 Anti-lipoprotein lipase antibody in systemic sclerosis: association with elevated serum triglyceride concentrations
Kopcho_2005_Arch.Biochem.Biophys_436_367 Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach
Lambert_2005_Environ.Health.Perspect_113_504 Variation in organophosphate pesticide metabolites in urine of children living in agricultural communities
Langston_2005_Lipids_40_31 Over-expression of hepatic neutral cytosolic cholesteryl ester hydrolase in mice increases free cholesterol and reduces expression of HMG-CoAR, CYP27, and CYP7A1
Levedakou_2005_Mol.Cell.Neurosci_28_757 Disruption of the mouse Large gene in the enr and myd mutants results in nerve, muscle, and neuromuscular junction defects
Li_2005_Zhonghua.Nei.Ke.Za.Zhi_44_188 [The value of coagulation factors in severity categorization of hepatitis B-related liver cirrhosis]
Li_2005_Biochem.Biophys.Res.Commun_330_1103 Neuronal differentiation of NTE-deficient embryonic stem cells
Lindsay_2005_Diabet.Med_22_654 Inhibition of dipeptidyl peptidase IV activity by oral metformin in Type 2 diabetes
Liu_2005_Toxicology_210_135 Dietary modulation of parathion-induced neurotoxicity in adult and juvenile rats
Liu_2005_J.Physiol_565_965 Opposing muscarinic and nicotinic modulation of hypoglossal motor output to genioglossus muscle in rats in vivo
Lohith_2005_J.Biotechnol_117_49 Lipase-catalyzed synthesis of L-phenylalanyl-D-glucose
Magnier_2005_Rev.Neurol.(Paris)_161_211 [Acetylcholinesterase inhibitor treatment for Alzheimer's disease: the experience in Picardy]
Mashour_2005_J.Clin.Anesth_17_122 Spinal anesthesia and Ogilvie's syndrome
Mauskopf_2005_J.Manag.Care.Pharm_11_231 Drug persistency patterns for patients treated with rivastigmine or donepezil in usual care settings
Mendes_2005_Clin.Toxicol.(Phila)_43_117 Acute intoxication due to ingestion of vegetables contaminated with aldicarb
Mine_2005_Biotechnol.Lett_27_383 Enhancement of enzyme activity and enantioselectivity by cyclopentyl methyl ether in the transesterification catalyzed by Pseudomonas cepacia lipase co-lyophilized with cyclodextrins
Miyasaka_2005_Pancreas_30_e87 Carboxylester lipase gene polymorphism as a risk of alcohol-induced pancreatitis
Morera_2005_Med.Clin.(Barc)_124_435 [Cholinesterase as a marker in acute septic conditions]
Mosbah_2005_Biochim.Biophys.Acta_1723_282 Biochemical and molecular characterization of Staphylococcus xylosus lipase
Mosca_2005_Clin.Chem.Lab.Med_43_256 National survey on the use of measurement of cholinesterase activity in serum
Moser_2005_Toxicol.Sci_86_101 Neurotoxicological and statistical analyses of a mixture of five organophosphorus pesticides using a ray design
Motamed_2005_Eur.J.Clin.Pharmacol_61_175 Interaction between mivacurium and pancuronium: impact of the order of administration
Nakamizo_2005_Biochem.Biophys.Res.Commun_330_1285 Stimulation of nicotinic acetylcholine receptors protects motor neurons
Nasstrom_2005_Nephrol.Dial.Transplant_20_1172 A single bolus of a low molecular weight heparin to patients on haemodialysis depletes lipoprotein lipase stores and retards triglyceride clearing
Needham_2005_Environ.Health.Perspect_113_494 Assessing exposure to organophosphorus pesticides by biomonitoring in epidemiologic studies of birth outcomes
Nikolaki_2005_J.Environ.Sci.Health.B_40_233 Photo-fenton assisted reaction of dimethoate in aqueous solutions
Pandey_2005_Ecotoxicol.Environ.Saf_61_114 Acute toxicity bioassays of mercuric chloride and malathion on air-breathing fish Channa punctatus (Bloch)
Patalay_2005_J.Nutr_135_735 The lowering of plasma lipids following a weight reduction program is related to increased expression of the LDL receptor and lipoprotein lipase
Patel_2005_J.Biol.Chem_280_22624 Activation of the lipid droplet controls the rate of lipolysis of triglycerides in the insect fat body
Poltyrev_2005_Psychopharmacology.(Berl)_181_118 Effect of chronic treatment with ladostigil (TV-3326) on anxiogenic and depressive-like behaviour and on activity of the hypothalamic-pituitary-adrenal axis in male and female prenatally stressed rats
Ranalletta_2005_Diabetes_54_935 Altered hepatic and muscle substrate utilization provoked by GLUT4 ablation
Roy_2005_J.Wildl.Dis_41_184 Plasma B-esterase activities in European raptors
Sadowsky_2005_Prim.Care.Companion.J.Clin.Psychiatry_7_43 Switching From Donepezil to Rivastigmine Is Well Tolerated: Results of an Open-Label Safety and Tolerability Study
Scherer_2005_JAMA_293_1906 Does this patient have myasthenia gravis?
Scremin_2005_Pharmacol.Biochem.Behav_80_529 Low-dose cholinesterase inhibitors do not induce delayed effects on cerebral blood flow and metabolism
Sekhon_2005_J.Basic.Microbiol_45_147 Properties of a thermostable extracellular lipase from Bacillus megaterium AKG-1
Shinn_2005_Curr.Med.Res.Opin_21_207 Effects of switching pravastatin to cerivastatin on C-reactive protein, butyrylcholinesterase, and lipids
Sotiropoulou_2005_Biosens.Bioelectron_20_2347 Genetically engineered acetylcholinesterase-based biosensor for attomolar detection of dichlorvos
Staaf_2005_J.Environ.Monit_7_344 Indoor air sampling of organophosphate triesters using solid phase extraction (SPE) adsorbents
Thetkathuek_2005_Chem.Pharm.Bull.(Tokyo)_53_422 Spectrophotometric determination of plasma and red blood cell cholinesterase activity of 53 fruit farm workers pre- and post-exposed chlorpyrifos for one fruit crop
Tien_2005_J.Toxicol.Sci_30_43 Roles of mu-opioid receptors in development of tolerance to diisopropylfluorophosphate (DFP)
Undeger_2005_Arch.Toxicol_79_169 Effects of pesticides on human peripheral lymphocytes in vitro: induction of DNA damage
Vakurov_2005_Biosens.Bioelectron_20_2324 Acetylecholinesterase-based biosensor electrodes for organophosphate pesticide detection. II. Immobilization and stabilization of acetylecholinesterase
Valincius_2005_Anal.Chem_77_2632 Electrochemical method for the detection of lipase activity
Vikbjerg_2005_Biotechnol.Prog_21_397 Lipase-catalyzed acyl exchange of soybean phosphatidylcholine in n-Hexane: a critical evaluation of both acyl incorporation and product recovery
Von Dannecker_2005_J.Neurosci_25_3793 Ric-8B, an olfactory putative GTP exchange factor, amplifies signal transduction through the olfactory-specific G-protein Galphaolf
Westers_2005_Appl.Environ.Microbiol_71_1899 Genes involved in SkfA killing factor production protect a Bacillus subtilis lipase against proteolysis
Xu_2005_Arch.Pharm.Res_28_180 In vitro inhibitory effect of triterpenoidal saponins from Platycodi Radix on pancreatic lipase
Yen_2005_Shock_23_353 Coenzyme q10 confers cardiovascular protection against acute mevinphos intoxication by ameliorating bioenergetic failure and hypoxia in the rostral ventrolateral medulla of the rat
Zhou_2005_J.Occup.Health_47_96 Memantine alleviates toxicity induced by dichlorvos in rats
Zimmermann_2005_Neurobiol.Dis_19_237 Cholinesterase inhibitors influence APP metabolism in Alzheimer disease patients
Abu_2005_Int.J.Occup.Environ.Health_11_144 Adverse impact of insecticides on the health of Palestinian farm workers in the Gaza Strip: a hematologic biomarker study
Akai_2005_Chem.Commun.(Camb)__2369 Lipase-catalyzed domino kinetic resolution of alpha-hydroxynitrones\/intramolecular 1,3-dipolar cycloaddition: a concise asymmetric total synthesis of (-)-rosmarinecine
Aleryani_2005_Clin.Chim.Acta_359_141 Fatty acid methyl esters are detectable in the plasma and their presence correlates with liver dysfunction
Bancerz_2005_J.Ind.Microbiol.Biotechnol_32_253 Cultivation conditions and properties of extracellular crude lipase from the psychrotrophic fungus Penicillium chrysogenum 9'
Bianchi_2005_Bioorg.Med.Chem.Lett_15_2711 Synthesis of tricyclic analogs of stephaoxocanidine and their evaluation as acetylcholinesterase inhibitors
Brun_2005_Environ.Sci.Technol_39_2786 Evaluation of a novel malathion immunoassay for groundwater and surface water analysis
Bullock_2005_Curr.Med.Res.Opin_21_1 Treatment of behavioural and psychiatric symptoms in dementia: implications of recent safety warnings
Burgos-Hernandez_2005_Bull.Environ.Contam.Toxicol_74_335 Detection and quantification of insecticides in shrimp grown in a coastal farm in Sonora, Mexico
Cai_2005_Space.Med.Med.Eng.(Beijing)_18_32 [Protective effect of Danzhi-xiaoyao San on rat brain energy or material metabolism (correction of matebolism) dealt with D-galactose]
Carriere_2005_JOP_6_206 Does the pancreas really produce much more lipase than required for fat digestion?
Cavallotti_2005_Neuroimmunomodulation_12_141 Cholinergic staining of bronchus- associated lymphoid tissue
Celik_2005_Prog.Neuropsychopharmacol.Biol.Psychiatry_29_505 The effects of chronic ethanol consumption and withdrawal on passive avoidance task and serum cholinesterase level in rats
Ceppa_2005_Ann.Fr.Anesth.Reanim_24_425 [Prolonged succinylcholine-induced apnoea associated with cholinesterase silent plasma variant]
Chennamaneni_2005_Bioorg.Med.Chem.Lett_15_3076 Quaternary salts of 4,3' and 4,4' bis-pyridinium monooximes: synthesis and biological activity
Cheon_2005_Biochem.Pharmacol_70_22 Inhibition of dipeptidyl peptidase IV by novel inhibitors with pyrazolidine scaffold
Clark_2005_Pharmacol.Biochem.Behav_81_497 Effects of physostigmine and human butyrylcholinesterase on acoustic startle reflex and prepulse inhibition in C57BL\/6J mice
Colombo_2005_Chemosphere_61_1665 Exposure to the organophosphorus pesticide chlorpyrifos inhibits acetylcholinesterase activity and affects muscular integrity in Xenopus laevis larvae
Cristalli_2005_J.Med.Chem_48_2763 Effects of 5'-phosphate derivatives of 2-hexynyl adenosine and 2-phenylethynyl adenosine on responses of human platelets mediated by P2Y receptors
Cummings_2005_Am.J.Psychiatry_162_645 Searching for methods to detect, prevent, and treat Alzheimer's disease
Das_2005_Pharmacol.Biochem.Behav_81_89 Role of molecular isoforms of acetylcholinesterase in learning and memory functions
De Jenlis_2005_Ultrasound.Obstet.Gynecol_25_607 Prenatal findings in epidermolysis bullosa with pyloric atresia in a family not known to be at risk
Deacon_2005_Curr.Opin.Investig.Drugs_6_419 MK-431 (Merck)
Deschenes-Furry_2005_J.Biol.Chem_280_25361 The RNA-binding protein HuR binds to acetylcholinesterase transcripts and regulates their expression in differentiating skeletal muscle cells
Destain_2005_Appl.Biochem.Biotechnol_121-124_269 Utilization of methyloleate in production of microbial lipase
Edmondson_2005_Bioorg.Med.Chem.Lett_15_3048 Discovery of potent and selective orally bioavailable beta-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors
Eggert_2005_Chembiochem_6_1062 Multiplex-PCR-based recombination as a novel high-fidelity method for directed evolution
El Ayass_2005_Eur.J.Anaesthesiol_22_197 Decreased mivacurium infusion rate and delayed neuromuscular recovery after metoclopramide: a randomized double blind placebo-controlled study
Ellis_2005_J.Am.Osteopath.Assoc_105_145 Cholinesterase inhibitors in the treatment of dementia
Engedal_2005_Tidsskr.Nor.Laegeforen_125_1188 [Assessment of dementia and use of anti-dementia drugs in nursing homes]
Ferheen_2005_Chem.Pharm.Bull.(Tokyo)_53_570 Haloxylines A and B, antifungal and cholinesterase inhibiting piperidine alkaloids from Haloxylon salicornicum
Fickers_2005_Curr.Microbiol_50_133 Involvement of hexokinase Hxk1 in glucose catabolite repression of LIP2 encoding extracellular lipase in the yeast Yarrowia lipolytica
Fidani_2005_Neurosci.Lett_384_102 Cholesteryl ester transfer protein TaqI B and lipoprotein lipase Ser447Ter gene polymorphisms are not associated with ischaemic stroke in Greek patients
Foldi_2005_Int.J.Geriatr.Psychiatry_20_485 Detecting effects of donepezil on visual selective attention using signal detection parameters in Alzheimer's disease
Fujiki_2005_Brain.Res_1043_236 Neuroprotective effect of donepezil, a nicotinic acetylcholine-receptor activator, on cerebral infarction in rats
Fujiwara_2005_Biochim.Biophys.Acta_1751_26 Regulation of human extravillous trophoblast function by membrane-bound peptidases
Fulton_2005_Clin.Toxicol.(Phila)_43_215 FFP in organophosphate poisoning: what's the secret ingredient?
Gardiner_2005_Pharmacogenet.Genomics_15_365 Pharmacogenetic testing for drug metabolizing enzymes: is it happening in practice?
Gauthier_2005_BMJ_330_857 Drugs for Alzheimer's disease and related dementias
Gilham_2005_Methods_36_139 Techniques to measure lipase and esterase activity in vitro
Gomez_2005_J.Chem.Neuroanat_29_238 Heterogeneous targeting of centrifugal inputs to the glomerular layer of the main olfactory bulb
Gonzalez-Gronow_2005_J.Biol.Chem_280_27173 Association of plasminogen with dipeptidyl peptidase IV and Na+\/H+ exchanger isoform NHE3 regulates invasion of human 1-LN prostate tumor cells
Guerrero_2005_Insect.Biochem.Mol.Biol_35_585 BmiGI: a database of cDNAs expressed in Boophilus microplus, the tropical\/southern cattle tick
Guo_2005_J.Chromatogr.Sci_43_158 A new analysis method with GC or GC-MS for the quick detection of pesticide residues in vegetables
Gutarra_2005_Appl.Biochem.Biotechnol_121-124_105 Lipase production by solid-state fermentation: cultivation conditions and operation of tray and packed-bed bioreactors
Guthrie_2005_Brain.Res.Dev.Brain.Res_157_162 Patterns of afferent projections to the dentate gyrus studied in organotypic co-cultures
Halamek_2005_Anal.Bioanal.Chem_382_1904 Sensitive detection of organophosphates in river water by means of a piezoelectric biosensor
Hall_2005_J.Environ.Sci.Health.A.Tox.Hazard.Subst.Environ.Eng_40_959 Temporal and spatial assessment of water quality, physical habitat, and benthic communities in an impaired agricultural stream in California's San Joaquin Valley
Hasan_2005_J.Enzyme.Inhib.Med.Chem_20_41 Synthesis and inhibitory potential towards acetylcholinesterase, butyrylcholinesterase and lipoxygenase of some variably substituted chalcones
Heintel_2005_Leukemia_19_1216 High expression of lipoprotein lipase in poor risk B-cell chronic lymphocytic leukemia
Hulkova_2005_Virchows.Arch_447_31 Lactosylceramide in lysosomal storage disorders: a comparative immunohistochemical and biochemical study
Icen_2005_J.Econ.Entomol_98_358 Biochemical stress indicators of greater wax moth exposure to organophosphorus insecticides
Jouanny_2005_Psychol.Neuropsychiatr.Vieil_3 Suppl 1_S51 [Pharmacological treatment in severe dementia]
Kamha_2005_Basic.Clin.Pharmacol.Toxicol_96_397 Organophosphate poisoning in pregnancy: a case report
Kandemirli_2005_Mini.Rev.Med.Chem_5_479 Human acetylcholinesterase inhibitors: electronic-topological and neural network approaches to the structure-activity relationships study
Karboune_2005_J.Biotechnol_119_281 Lipase-catalyzed biosynthesis of cinnamoylated lipids in a selected organic solvent medium
Kessler_2005_Nervenarzt_76_581 [The role of copper in the pathophysiology of Alzheimer's disease]
Kimura_2005_Ind.Health_43_285 Effects of pesticides on the peripheral and central nervous system in tobacco farmers in Malaysia: studies on peripheral nerve conduction, brain-evoked potentials and computerized posturography
Kimura_2005_Brain.Res_1047_72 Protective effect of donepezil against Abeta(1-40) neurotoxicity in rat septal neurons
Kleinschmidt_2005_Anaesthesist_54_791 [Cholinesterase inhibitors. Importance in anaesthesia, intensive care medicine, emergency medicine and pain therapy]
Krasinski_2005_J.Am.Chem.Soc_127_6686 In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors
Krivoy_2005_Harefuah_144_266 [Medical management in the chemical terrorism scene]
Ledowski_2005_Eur.J.Anaesthesiol_22_289 Pseudocholinesterase activity increases and heart rate variability decreases with preoperative anxiety
Li_2005_J.Econ.Entomol_98_552 Carbaryl resistance in Mexican strains of the southern cattle tick (Acari: Ixodidae)
Lianghua_2005_Appl.Biochem.Biotechnol_125_139 Purification and partial characterization of a lipase from Bacillus coagulans ZJU318
Linnebur_2005_Am.J.Health.Syst.Pharm_62_923 Cholinesterase inhibitor use in geriatric outpatients with dementia
Lunder_2005_J.Lipid.Res_46_1512 Peptide inhibitor of pancreatic lipase selected by phage display using different elution strategies
MacIntyre_2005_Pest.Manag.Sci_61_809 Resistance of Thrips tabaci to pyrethroid and organophosphorus insecticides in Ontario, Canada
Maidment_2005_Acta.Psychiatr.Scand_111_403 A review of studies describing the use of acetyl cholinesterase inhibitors in Parkinson's disease dementia
Mannucci_2005_Diabetologia_48_1168 Hyperglycaemia increases dipeptidyl peptidase IV activity in diabetes mellitus
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Ng_2005_Biotechnol.Bioeng_91_106 Partially purified Carica papaya lipase: a versatile biocatalyst for the hydrolytic resolution of (R,S)-2-arylpropionic thioesters in water-saturated organic solvents
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Onyido_2005_Org.Biomol.Chem_3_1468 Catalysis of the ethanolysis of aryl methyl phenyl phosphinate esters by alkali metal ions: transition state structures for uncatalyzed and metal ion-catalyzed reactions
Ostergaard_2005_Anesthesiology_102_1124 Pharmacokinetics and pharmacodynamics of mivacurium in patients phenotypically homozygous for the atypical plasma cholinesterase variant: effect of injection of human cholinesterase
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Rohm_2005_Anaesthesia_60_433 Physostigmine for the prevention of postanaesthetic shivering following general anaesthesia - a placebo-controlled comparison with nefopam
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Chouteau_2005_Biosens.Bioelectron_21_273 A bi-enzymatic whole cell conductometric biosensor for heavy metal ions and pesticides detection in water samples
Coggan_2005_Science_309_446 Evidence for ectopic neurotransmission at a neuronal synapse
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Cook_2005_Environ.Toxicol.Chem_24_1745 The pesticide malathion reduces survival and growth in developing zebrafish
Correa-Basurto_2005_Eur.J.Med.Chem_40_732 p-Aminobenzoic acid derivatives as acetylcholinesterase inhibitors
Cox_2005_Clin.Toxicol.(Phila)_43_243 Evaluation of potential adverse health effects resulting from chronic domestic exposure to the organophosphate insecticide methyl parathion
Csernansky_2005_Neuropsychopharmacology_30_2135 Cholinesterase inhibitors ameliorate behavioral deficits induced by MK-801 in mice
Dabisch_2005_J.Ocul.Pharmacol.Ther_21_182 Tolerance to the miotic effect of sarin vapor in rats after multiple low-level exposures
Dani_2005_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_141_373 Hydrolase activity in the venom of the pupal endoparasitic wasp, Pimpla hypochondriaca
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Demuth_2005_Biochim.Biophys.Acta_1751_33 Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors
Desai_2005_Neurology_64_S34 Diagnosis and treatment of Alzheimer's disease
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Doody_2005_Geriatrics_Suppl_14 Refining treatment guidelines in Alzheimer's disease
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Feldman_2005_Int.J.Geriatr.Psychiatry_20_559 Efficacy and safety of donepezil in patients with more severe Alzheimer's disease: a subgroup analysis from a randomized, placebo-controlled trial
Feldman_2005_Am.J.Geriatr.Psychiatry_13_645 Mild cognitive impairment
Fillit_2005_Am.J.Geriatr.Pharmacother_3_39 Economics of dementia and pharmacoeconomics of dementia therapy
Flirski_2005_Curr.Alzheimer.Res_2_47 Biochemical markers and risk factors of Alzheimer's disease
Freudenreich_2005_Drugs.Today.(Barc)_41_411 Drug-induced sialorrhea
Furlan_2005_Br.J.Pharmacol_146_389 Developing skeletal muscle cells express functional muscarinic acetylcholine receptors coupled to different intracellular signaling systems
Furlong_2005_Neurotoxicol_26_651 Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants
Fuxreiter_2005_Proteins_60_504 Flexibility of prolyl oligopeptidase: molecular dynamics and molecular framework analysis of the potential substrate pathways
Gabel_2005_Biophys.J_89_3303 Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study
Gao_2005_J.Invest.Dermatol_124_1259 Identification of a novel keratinocyte retinyl ester hydrolase as a transacylase and lipase
Gasper_2005_Am.J.Geriatr.Pharmacother_3_1 Is donepezil therapy associated with reduced mortality in nursing home residents with dementia?
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Ghisdal_2005_Eur.J.Pharmacol_517_97 The diacylglycerol lipase inhibitor RHC-80267 potentiates the relaxation to acetylcholine in rat mesenteric artery by anti-cholinesterase action
Gilbert_2005_Front.Biosci_10_2177 Evolution of clams (cholinesterase-like adhesion molecules): structure and function during development
Goodarzi_2005_J.Clin.Endocrinol.Metab_90_4816 The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity
Greve_2005_Int.Psychogeriatr_17_195 A survey of Australian and New Zealand old age psychiatrists' preferred medications to treat behavioral and psychological symptoms of dementia (BPSD)
Gu_2005_World.J.Gastroenterol_11_4604 Alterations of serum cholinesterase in patients with gastric cancer
Guerin_2005_Am.J.Clin.Nutr_82_435 Different modes of weight loss in Alzheimer disease: a prospective study of 395 patients
Gupta_2005_Eur.J.Mass.Spectrom.(Chichester)_11_119 Mass spectral studies on synthetic analogs of organophosphorus toxin occurring in dinoflagellate algae
Gupta_2005_Biochim.Biophys.Acta_1725_81 Hazardous effect of organophosphate compound, dichlorvos in transgenic Drosophila melanogaster (hsp70-lacZ): induction of hsp70, anti-oxidant enzymes and inhibition of acetylcholinesterase
Hagiwara_2005_Neurosci.Lett_390_61 Cholinergic systems in the posterior hypothalamic nucleus are involved in blood pressure decrease-induced excitation of anterior hypothalamic area neurons in rats
Hartonian_2005_Restor.Neurol.Neurosci_23_87 Compensatory changes in cortical cholinergic innervation in the rat following an immunotoxic lesion
Hasin_2005_Curr.Alzheimer.Res_2_207 Analysis of genetic polymorphisms in acetylcholinesterase as reflected in different populations
Hay_2005_Bioorg.Med.Chem_13_4043 Nitroarylmethylcarbamate prodrugs of doxorubicin for use with nitroreductase gene-directed enzyme prodrug therapy
Hernandez_2005_Toxicol.Lett_159_13 Changes in erythrocyte enzymes in humans long-term exposed to pesticides: influence of several markers of individual susceptibility
Hetherington_2005_Pediatr.Emerg.Care_21_546 Myasthenia gravis: myasthenia vs. cholinergic crisis
Hodl_2005_MMW.Fortschr.Med_147_40 [Mild cognitive impairment: A review of the literature]
Hossain_2005_Life.Sci_77_795 Neuromechanical effects of pyrethroids, allethrin, cyhalothrin and deltamethrin on the cholinergic processes in rat brain
Houghton_2005_Neurosignals_14_6 Natural products and derivatives affecting neurotransmission relevant to Alzheimer's and Parkinson's disease
Howard_2005_Toxicol.Appl.Pharmacol_207_112 Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures
Hsiung_2005_Peptides_26_1988 Potent peptide agonists for human melanocortin 3 and 4 receptors derived from enzymatic cleavages of human beta-MSH(5-22) by dipeptidyl peptidase I and dipeptidyl peptidase IV
Iarlori_2005_Exp.Gerontol_40_605 Expression and production of two selected beta-chemokines in peripheral blood mononuclear cells from patients with Alzheimer's disease
Illa_2005_Med.Clin.(Barc)_125_100 [Seronegative myasthenia gravis and antiMuSK positive antibodies: description of Spanish series]
Inestrosa_2005_Curr.Alzheimer.Res_2_301 Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway
Janowsky_2005_Pharmacol.Biochem.Behav_81_917 Anticholinesterase (DFP) toxicity antagonism by chronic donepezil: a potential nerve agent treatment
Joray_2005_Rev.Med.Suisse_1_1201 [Is there a treatment for Alzheimer's disease?]
Kaduszkiewicz_2005_BMJ_331_321 Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials
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Kaizer_2005_J.Inorg.Biochem_99_1865 Acetylcholinesterase activation and enhanced lipid peroxidation after long-term exposure to low levels of aluminum on different mouse brain regions
Kalender_2005_Toxicology_211_197 Diazinon-induced hepatotoxicity and protective effect of vitamin E on some biochemical indices and ultrastructural changes
Kang_2005_J.Biotechnol_119_147 Real time measurement and control of thermodynamic water activities for enzymatic catalysis in hexane
Kapaki_2005_Curr.Med.Res.Opin_21_871 The cognitive effects of cholinesterase inhibitor treatment in every-day practice
Karachaliou_2005_Int.J.Clin.Pract.Suppl__40 An increase in creatine kinase secondary to acute pancreatitis: a case report
Kariola_2005_Plant.Cell_17_282 Chlorophyllase 1, a damage control enzyme, affects the balance between defense pathways in plants
Kelly_2005_Drug.Resist.Updat_8_51 Fibroblast activation protein-alpha and dipeptidyl peptidase IV (CD26): cell-surface proteases that activate cell signaling and are potential targets for cancer therapy
Khalid_2005_Biochem.Biophys.Res.Commun_331_1528 Structural basis of acetylcholinesterase inhibition by triterpenoidal alkaloids
Kirrane_2005_Am.J.Epidemiol_161_1020 Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health study
Kondo_2005_Eur.J.Cardiothorac.Surg_28_22 Myasthenia gravis appearing after thymectomy for thymoma
Korchounov_2005_Exp.Brain.Res_164_399 Modification of motor cortical excitability by an acetylcholinesterase inhibitor
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Kuczewski_2005_J.Physiol_566_907 Acetylcholine modulates cortical synaptic transmission via different muscarinic receptors, as studied with receptor knockout mice
Kuster_2005_Aquat.Toxicol_75_76 Cholin- and carboxylesterase activities in developing zebrafish embryos (Danio rerio) and their potential use for insecticide hazard assessment
Lai_2005_N.Engl.J.Med_353_317 Pesticide-like poisoning from a prescription drug
Langston_2005_Neurotoxicol.Teratol_27_841 Effects of sarin on the operant behavior of guinea pigs
Lanzarot_2005_J.Wildl.Dis_41_379 Hematologic, protein electrophoresis, biochemistry, and cholinesterase values of free-living black stork nestlings (Ciconia nigra)
Lautar_2005_Brain.Res_1048_177 DPP IV inhibitor blocks mescaline-induced scratching and amphetamine-induced hyperactivity in mice
Lei_2005_Biotechnol.Prog_21_678 Improved degradation of organophosphorus nerve agents and p-nitrophenol by Pseudomonas putida JS444 with surface-expressed organophosphorus hydrolase
Leinio_2005_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_140_408 Seasonal variability in biomarkers in the bivalves Mytilus edulis and Macoma balthica from the northern Baltic Sea
Leonard_2005_J.Pharm.Sci_94_1736 Development of a novel high-concentration galantamine formulation suitable for intranasal delivery
Lieben_2005_Neuropsychopharmacology_30_2169 The selective 5-HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat
Lin_2005_Chem.Res.Toxicol_18_1124 Ortho effects for inhibition mechanisms of butyrylcholinesterase by o-substituted phenyl N-butyl carbamates and comparison with acetylcholinesterase, cholesterol esterase, and lipase
Lingler_2005_J.Am.Geriatr.Soc_53_983 Caregiver-specific outcomes in antidementia clinical drug trials: a systematic review and meta-analysis
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Lu_2005_Bioorg.Med.Chem.Lett_15_3271 Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors
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Mackowiak-Cordoliani_2005_Drugs.Aging_22_483 Poststroke dementia in the elderly
Malhotra_2005_Chirality_17 Suppl_S240 Enantioseparation of the esters of alpha-N-acetyl amino acids by lipase in ionic liquid
Malomouzh_2005_J.Neurochem_94_257 Effect of N-acetylaspartylglutamate (NAAG) on non-quantal and spontaneous quantal release of acetylcholine at the neuromuscular synapse of rat
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Matozzo_2005_Mar.Pollut.Bull_50_1686 Acetylcholinesterase as a biomarker of exposure to neurotoxic compounds in the clam Tapes philippinarum from the Lagoon of Venice
Matsuura_2005_Anal.Chem_77_4235 Electrochemical enzyme immunoassay of a peptide hormone at picomolar levels
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McArdle_2005_Neuropharmacol_49_1132 Mefloquine inhibits cholinesterases at the mouse neuromuscular junction
Mehta_2005_Behav.Brain.Res_163_227 Evidence for the involvement of central serotonergic mechanisms in cholinergic tremor induced by tacrine in Balb\/c mice
Meshorer_2005_Mol.Psychiatry_10_985 SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNA
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Moriguchi_2005_J.Pharmacol.Exp.Ther_315_125 Modulation of N-methyl-D-aspartate receptors by donepezil in rat cortical neurons
Morris_2005_Geriatrics_Suppl_9 Mild cognitive impairment and preclinical Alzheimer's disease
Muacevic-Kataneca_2005_Arzneimittelforschung_55_271 Clinical study on the effect of simvastatin on butyrylcholinesterase activity
Mulder_2005_Behav.Brain.Res_163_33 Galantamine-induced behavioral recovery after sublethal excitotoxic lesions to the rat medial septum
Murphy_2005_Anesth.Analg_100_1840 Residual paralysis at the time of tracheal extubation
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Narbonne_2005_Biomarkers_10_58 Scale of classification based on biochemical markers in mussels: application to pollution monitoring in Mediterranean coasts and temporal trends
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Okamura_2005_Toxicology_213_129 A comprehensive evaluation of the testicular toxicity of dichlorvos in Wistar rats
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Prodanov_2005_Muscle.Nerve_32_292 Three-dimensional topography of the motor endplates of the rat gastrocnemius muscle
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Biederer_2005_Sci.STKE_2005_pe9 Progress from the postsynaptic side: signaling in synaptic differentiation
Binelli_2005_Chemosphere_61_1074 Screening of POP pollution by AChE and EROD activities in Zebra mussels from the Italian Great Lakes
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Borowitz_2005_Curr.Opin.Pulm.Med_11_524 Update on the evaluation of pancreatic exocrine status in cystic fibrosis
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Carvalho_2005_FEBS.J_272_5584 Biochemical characterization of human umbilical vein endothelial cell membrane bound acetylcholinesterase
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Chilukuri_2005_Chem.Biol.Interact_157-158_115 Polyethylene glycosylation prolongs the circulatory stability of recombinant human butyrylcholinesterase
Chiou_2005_BMC.Biochem_6_17 Probing stereoselective inhibition of the acyl binding site of cholesterol esterase with four diastereomers of 2'-N-alpha-methylbenzylcarbamyl-1, 1'-bi-2-naphthol
Choudhary_2005_Chem.Pharm.Bull.(Tokyo)_53_1455 Microbial hydroxylation of pregnenolone derivatives
Chubykin_2005_J.Biol.Chem_280_22365 Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism
Cline_2005_Curr.Biol_15_R203 Synaptogenesis: a balancing act between excitation and inhibition
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Connelly_2005_Org.Biomol.Chem_3_3260 Synthesis and characterisation of a ligand that forms a stable tetrahedral intermediate in the active site of the Aureobacterium species (-) gamma-lactamase
Craft_2005_Eur.J.Neurosci_21_3117 Microsphere embolism-induced cortical cholinergic deafferentation and impairments in attentional performance
Cummings_2005_CNS.Spectr_10_22 Behavioral and neuropsychiatric outcomes in Alzheimer's disease
Cuprian_2005_Br.J.Pharmacol_146_927 Cholinergic innervation of the mouse isolated vas deferens
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da Silva_2005_Ecotoxicol.Environ.Saf_62_376 Effects of salinity on biomarker responses in Crassostrea rhizophorae (Mollusca, Bivalvia) exposed to diesel oil
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Dasgupta_2005_J.Colloid.Interface.Sci_289_566 Surfactant tail length-dependent lipase activity profile in cationic water-in-oil microemulsions
Datta_2005_J.Dairy.Res_72_393 Significance of frictional heating for effects of high pressure homogenisation on milk
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Desai_2005_Expert.Rev.Neurother_5_563 Rivastigmine for Alzheimer's disease
Descamps_2005_J.Lipid.Res_46_2405 Lipoprotein metabolism of pregnant women is associated with both their genetic polymorphisms and those of their newborn children
Deschenes-Furry_2005_Chem.Biol.Interact_157-158_43 Role of ELAV-like RNA-binding proteins HuD and HuR in the post-transcriptional regulation of acetylcholinesterase in neurons and skeletal muscle cells
Dhaunsi_2005_Med.Princ.Pract_14 Suppl 1_92 Very-long-chain fatty acids activate lysosomal hydrolases in neonatal human skin tissue
Dickerson_2005_Biochemistry_44_14845 Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library
Dimpfel_2005_Eur.Neuropsychopharmacol_15_673 Pharmacological modulation of cholinergic brain activity and its reflection in special EEG frequency ranges from various brain areas in the freely moving rat (Tele-Stereo-EEG)
Doi_2005_Pediatr.Surg.Int_21_889 Complete innervation profile of whole bowel resected at pull-through for Hirschsprung's disease. Unexpected findings
Donsmark_2005_Exerc.Sport.Sci.Rev_33_127 Hormone-sensitive lipase as mediator of lipolysis in contracting skeletal muscle
Ducho_2005_Nucleosides.Nucleotides.Nucleic.Acids_24_519 Novel cyclosal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase
Eldeen_2005_J.Ethnopharmacol_102_457 Antibacterial, anti-inflammatory, anti-cholinesterase and mutagenic effects of extracts obtained from some trees used in South African traditional medicine
Ema_2005_Chem.Commun.(Camb)__4650 Rational control of enantioselectivity of lipase by site-directed mutagenesis based on the mechanism
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Eskander_2005_Brain.Res_1060_144 Rivastigmine is a potent inhibitor of acetyl- and butyrylcholinesterase in Alzheimer's plaques and tangles
Evran_2005_Prep.Biochem.Biotechnol_35_191 Modification of porcine pancreatic lipase with Z-proline
Fabel_2005_J.Chromatogr.A_1099_103 Effect-directed analysis by high-performance liquid chromatography with gas-segmented enzyme inhibition
Farriol_2005_Clin.Nutr_24_1099 Dipeptidyl-peptidase IV in patients with short bowel syndrome
Feng_2005_Yi.Chuan.Xue.Bao_32_864 [Genomic analysis of serine carboxypeptidase-like protein family of Arabidopsis thaliana]
Fenton_2005_Bull.Entomol.Res_95_483 The attack of the clones: tracking the movement of insecticide-resistant peach-potato aphids Myzus persicae (Hemiptera: Aphididae)
Fiegenbaum_2005_Clin.Chim.Acta_362_182 Pharmacogenetic study of apolipoprotein E, cholesteryl ester transfer protein and hepatic lipase genes and simvastatin therapy in Brazilian subjects
Forchetti_2005_Prim.Care.Companion.J.Clin.Psychiatry_7_155 Treating patients with moderate to severe Alzheimer's disease: implications of recent pharmacologic studies
Fournier_2005_Chem.Biol.Interact_157-158_257 Mutations of acetylcholinesterase which confer insecticide resistance in insect populations
Francis_2005_CNS.Spectr_10_6 The interplay of neurotransmitters in Alzheimer's disease
Frasco_2005_Biomarkers_10_360 Do metals inhibit acetylcholinesterase (AChE)? Implementation of assay conditions for the use of AChE activity as a biomarker of metal toxicity
French_2005_Drugs.Aging_22_877 Outpatient medications and hip fractures in the US: a national veterans study
Freo_2005_Am.J.Psychiatry_162_2061 Pharmacological modulation of prefrontal cortical activity during a working memory task in young and older humans: a PET study with physostigmine
Fucinos_2005_Biotechnol.Prog_21_1198 Production of thermostable lipolytic activity by thermus species
Fujimura_2005_Eur.J.Med.Res_10_278 Dipeptidyl peptidase IV of Streptococcus anginosus: purification and characterization
Funke_2005_Protein.Eng.Des.Sel_18_509 Combination of computational prescreening and experimental library construction can accelerate enzyme optimization by directed evolution
Futamura_2005_Biosci.Biotechnol.Biochem_69_1892 Efficient route to (S)-azetidine-2-carboxylic acid
Garcia-Castellanos_2005_Cell.Mol.Life.Sci_62_1996 Detailed molecular comparison between the inhibition mode of A\/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin
Geller_2005_Doc.Ophthalmol_110_79 Repeated spike exposure to the insecticide chlorpyrifos interferes with the recovery of visual sensitivity in rats
Gewert_2005_Clin.Chem.Lab.Med_43_1211 Specificity of the 3H-triolein assay for pancreatic lipase in blood plasma
Geyer_2005_Chem.Biol.Interact_157-158_331 Purification of transgenic plant-derived recombinant human acetylcholinesterase-R
Gilmer_2005_Chem.Biol.Interact_157-158_317 Novel isosorbide-based substrates for human butyrylcholinesterase
Gopalapillai_2005_Insect.Biochem.Mol.Biol_35_1171 Molecular cloning and analysis of a novel teratocyte-specific carboxylesterase from the parasitic wasp, Dinocampus coccinellae
Goudriaan_2005_J.Lipid.Res_46_2175 CD36 deficiency in mice impairs lipoprotein lipase-mediated triglyceride clearance
Gould_2005_Behav.Brain.Res_165_160 Age-related deficits in the retention of memories for cued fear conditioning are reversed by galantamine treatment
Green_2005_Diabetes.Obes.Metab_7_595 A comparison of the cellular and biological properties of DPP-IV-resistant N-glucitol analogues of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide
Gronke_2005_Cell.Metab_1_323 Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
Grossberg_2005_Curr.Med.Res.Opin_21_1631 Effect of rivastigmine in the treatment of behavioral disturbances associated with dementia: review of neuropsychiatric impairment in Alzheimer's disease
Grossberg_2005_CNS.Spectr_10_17 Rationalizing therapeutic approaches in Alzheimer's disease
Grynbaum_2005_J.Sep.Sci_28_1685 Unambiguous detection of astaxanthin and astaxanthin fatty acid esters in krill (Euphausia superba Dana)
Guerra_2005_Chem.Biol.Interact_157-158_57 Acetylcholinesterase and molecular interactions at the neuromuscular junction
Gutierrez_2005_J.Agric.Food.Chem_53_7701 Bioactive metabolites from the fungus Nectria galligena, the main apple canker agent in Chile
Halimi_2005_Biochim.Biophys.Acta_1753_247 Closed and open conformations of the lid domain induce different patterns of human pancreatic lipase antigenicity and immunogenicity
Hamani_2005_Braz.J.Med.Biol.Res_38_1677 Neo-Timm staining in the thalamus of chronically epileptic rats
Hansson_2005_J.Lipid.Res_46_2614 Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice
Hirano_2005_Carbohydr.Res_340_2297 Preparation of the methyl ester of hyaluronan and its enzymatic degradation
Hirata_2005_Seikagaku_77_1200 [Role of endothelial lipase in lipid metabolism and atherosclerosis]
Hiratake_2005_Chem.Rec_5_209 Enzyme inhibitors as chemical tools to study enzyme catalysis: rational design, synthesis, and applications
Hiura_2005_Okajimas.Folia.Anat.Jpn_82_57 Induction of corneal lesion and nerve fiber sprouting by neonatal capsaicin application depends on the dose of the drug and survival time after treatment
Hoerr_2005_Phytomedicine_12_598 Treatment effects of EGb 761 and cholinesterase inhibitors--why available studies do not demonstrate superiority of the latter
Hosia-Randell_2005_Drugs.Aging_22_793 Use of psychotropic drugs in elderly nursing home residents with and without dementia in Helsinki, Finland
Hu_2005_Brain.Res_1060_26 A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models
Huang_2005_Chem.Res.Toxicol_18_1371 Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases
Hulin_2005_Bioorg.Med.Chem.Lett_15_4770 New fluorinated pyrrolidine and azetidine amides as dipeptidyl peptidase IV inhibitors
Hussain_2005_Science_307_1207 Neuroscience. Making synapses: a balancing act
Ignatjev_2005_Anal.Biochem_344_275 Direct amperometric determination of lipase activity
Ishihara_2005_Pediatr.Surg.Int_21_878 Prospective analysis of primary modified Georgeson's laparoscopy-assisted endorectal pull-through for Hirschsprung's disease: short- to mid-term results
Ishikawa_2005_J.Neurooncol_74_283 Irinotecan therapy in a 12-year-old girl with recurrent brain stem glioma and without functional polymorphisms in UGT1A1 activity: case report
Iturralde_2005_Apoptosis_10_1369 Characterization of the lipolytic pathways that mediate free fatty acid release during Fas\/CD95-induced apoptosis
Jarho_2005_J.Med.Chem_48_4772 Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions
Jeppesen_2005_Gut_54_1224 Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients
Jin_2005_J.Biol.Chem_280_36551 Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase
Jing-Ping_2005_Brain.Res.Mol.Brain.Res_135_204 p55 protein is a member of PSD scaffold proteins in the rat brain and interacts with various PSD proteins
Johansson_2005_J.Mol.Biol_351_1048 Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function
Johnson_2005_Environ.Toxicol.Chem_24_2074 Influence of water temperature on acetylcholinesterase activity in the Pacific tree frog (Hyla regilla)
Kalkan_2005_Hum.Exp.Toxicol_24_369 Efficacy of an adenosine A1 receptor agonist compared with atropine and pralidoxime in a rat model of organophosphate poisoning
Kapkova_2005_J.Med.Chem_48_7496 Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor
Karthikeyan_2005_Indian.J.Exp.Biol_43_548 Detection of genetic polymorphism in the populations of brinjal shoot and fruit borer, Leucinodes orbonalis (Guenee)
Kawai_2005_Pediatr.Surg.Int_21_850 Cow's milk allergy presenting Hirschsprung's disease-mimicking symptoms
Kawashiri_2005_J.Clin.Endocrinol.Metab_90_6541 Long-term course of lipoprotein lipase (LPL) deficiency due to homozygous LPL(Arita) in a patient with recurrent pancreatitis, retained glucose tolerance, and atherosclerosis
Khattak_2005_Nat.Prod.Res_19_567 In vitro enzyme inhibition activities of crude ethanolic extracts derived from medicinal plants of Pakistan
Kikkawa_2005_Biochim.Biophys.Acta_1751_45 Dipeptidyl peptidase IV in tumor progression
Kim_2005_J.Agric.Food.Chem_53_8033 Modeling of lipase-catalyzed acidolysis of sesame oil and caprylic Acid by response surface methodology: optimization of reaction conditions by considering both acyl incorporation and migration
Kim_2005_Phytother.Res_19_359 Screening of Korean medicinal plants for lipase inhibitory activity
Kim_2005_Eur.J.Pharmacol_518_63 KR-62436, 6-{2-[2-(5-cyano-4,5-dihydropyrazol-1-yl)-2-oxoethylamino]ethylamino}nicotinonitr ile, is a novel dipeptidyl peptidase-IV (DPP-IV) inhibitor with anti-hyperglycemic activity
Kim_2005_Eur.J.Pharmacol_525_135 Protection by a transdermal patch containing physostigmine and procyclidine of soman poisoning in dogs
Kimura_2005_Neurosci.Lett_391_17 Comparison of donepezil and memantine for protective effect against amyloid-beta(1-42) toxicity in rat septal neurons
Ko_2005_J.Lipid.Res_46_2586 Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-\/- and LDLR-\/- mice
Koontz_2005_Am.J.Alzheimers.Dis.Other.Demen_20_295 Effects of galantamine on working memory and global functioning in patients with mild cognitive impairment: a double-blind placebo-controlled study
Korza_2005_J.Biol.Chem_280_40802 Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow
Kota_2005_J.Biol.Chem_280_31076 Differential effects of lipoprotein lipase on tumor necrosis factor-alpha and interferon-gamma-mediated gene expression in human endothelial cells
Kralisch_2005_Mol.Cell.Endocrinol_240_43 Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes
Krejcova-Kunesova_2005_Toxicology_216_32 Signs of cyclosarin-induced neurotoxicity and its pharmacological treatment with quaternary pyridinium-oximes reactivators
Krokosz_2005_Cell.Mol.Biol.Lett_10_471 Changes in the activity of acetylcholinesterase and Na,K-ATPase in human erythrocytes irradiated with X-rays
Kubo_2005_Brain.Res_1061_36 Posterior hypothalamus cholinergic stimulation-induced activation of anterior hypothalamic area neurons is enhanced in spontaneously hypertensive rats
Kuca_2005_J.Enzyme.Inhib.Med.Chem_20_227 In vitro reactivation of sarin-inhibited brain acetylcholinesterase from different species by various oximes
Labow_2005_J.Biomater.Sci.Polym.Ed_16_1167 Polycarbonate-urethane hard segment type influences esterase substrate specificity for human-macrophage-mediated biodegradation
Lahoz_2005_Atherosclerosis_182_129 The -514C\/T polymorphism of the hepatic lipase gene significantly modulates the HDL-cholesterol response to statin treatment
Lan_2005_Bull.Environ.Contam.Toxicol_75_335 Biodegradation of pesticide pollutants by two kinds of enzymes coexpressed in genetically engineered bacteria
Lang_2005_Fortschr.Neurol.Psychiatr_73_495 [Dementia with argyrophilic grains]
Langin_2005_Diabetes_54_3190 Adipocyte lipases and defect of lipolysis in human obesity
Lankas_2005_Diabetes_54_2988 Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9
Lauterbach_2005_Minerva.Med_96_155 The neuropsychiatry of Parkinson's disease
Layer_2005_Chem.Biol.Interact_157-158_37 On the multifunctionality of cholinesterases
Lechpammer_2005_Exp.Hematol_33_1201 Adipocyte differentiation in Sod2(-\/-) and Sod2(+\/+) murine bone marrow stromal cells is associated with low antioxidant pools
Lei_2005_Yi.Chuan.Xue.Bao_32_354 [Sequence and polymorphism analysis of porcine hormone-sensitive lipase gene 5'-UTR and exon I]
Levario-Carrillo_2005_Mutat.Res_586_68 Micronucleus frequency in human umbilical cord lymphocytes
Levinson_2005_J.Biol.Chem_280_17312 Neuroligins mediate excitatory and inhibitory synapse formation: involvement of PSD-95 and neurexin-1beta in neuroligin-induced synaptic specificity
Levinson_2005_Mol.Pain_1_12 New players tip the scales in the balance between excitatory and inhibitory synapses
Li_2005_Biochem.Pharmacol_70_1673 Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma
Li_2005_Int.J.Occup.Med.Environ.Health_18_133 Polymorphisms of microsomal epoxide hydrolase in French vinyl chloride workers
Liao_2005_J.Neurochem_95_160 Local proteins associated with methamphetamine-induced nigrostriatal dopaminergic neurotoxicity
Lin_2005_J.Biochem.Mol.Toxicol_19_234 Probing the peripheral anionic site of acetylcholinesterase with quantitative structure activity relationships for inhibition by biphenyl-4-acyoxylate-4'-N-Butylcarbamates
Lindner_2005_Mol.Nutr.Food.Res_49_972 Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations
Liu_2005_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_822_91 Immobilization of lipase onto micron-size magnetic beads
Ljusberg-Wahren_2005_Int.J.Pharm_298_328 Enzymatic characterization of lipid-based drug delivery systems
Loke_2005_Eur.J.Pharmacol_521_59 Novel neuroprotective effects with O-benzyl derivative of pralidoxime in soman-intoxicated rodents
Long_2005_Diabetologia_48_2354 Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle
Lu_2005_Am.J.Geriatr.Pharmacother_3_92 Impact of donepezil use in routine clinical practice on health care costs in patients with Alzheimer's disease and related dementias enrolled in a large medicare managed care plan: a case-control study
Lucic_2005_Acta.Pharm_55_177 Butyrylcholinesterase activity and plasma lipids in dexamethasone treated rats
Lund_2005_Ugeskr.Laeger_167_3195 [Parathion poisoning still occurs]
Lutz_2005_Int.J.Occup.Med.Environ.Health_18_115 Amphetamine- and scopolamine-induced locomotor activity following treatment with chlorphenvinphos or chlorphyriphos in rats
MacGregor_2005_Regul.Toxicol.Pharmacol_43_150 Humans appear no more sensitive than laboratory animals to the inhibition of red blood cell cholinesterase by dichlorvos
Magid_2005_Phytochemistry_66_2714 Acylated farnesyl diglycosides from Guioa crenulata
Mamdani_2005_Am.J.Geriatr.Psychiatry_13_892 Mental health-related drug utilization among older adults: prevalence, trends, and costs
Manso_2005_Int.J.Food.Microbiol_105_119 Isolation and characterisation of a Lactobacillus helveticus ITG LH1 peptidase-rich sub-proteome
Marcais_2005_J.Clin.Invest_115_2862 Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment
Marcol_2005_Microsurgery_25_486 Extracts obtained from predegenerated nerves improve functional recovery after sciatic nerve transection
Marinou_2005_Metab.Brain.Dis_20_227 Suckling rat brain regional distribution of acetylcholinesterase activity in galactosaemia in vitro
Martin-Cuadrado_2005_Mol.Biol.Cell_16_4867 Role of septins and the exocyst complex in the function of hydrolytic enzymes responsible for fission yeast cell separation
Martucciello_2005_J.Pediatr.Surg_40_1527 Controversies concerning diagnostic guidelines for anomalies of the enteric nervous system: a report from the fourth International Symposium on Hirschsprung's disease and related neurocristopathies
Masson_2005_Chem.Biol.Interact_157-158_143 Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics
Massoulie_2005_Chem.Biol.Interact_157-158_3 The C-terminal peptides of acetylcholinesterase: cellular trafficking, oligomerization and functional anchoring
Mattes_2005_Physiol.Behav_86_691 Fat taste and lipid metabolism in humans
McKeith_2005_Neurology_65_1863 Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium
Mehta_2005_Neurology_65_159 Ethnic differences in acetylcholinesterase inhibitor use for Alzheimer disease
Mekonnen_2005_Occup.Med.(Lond)_55_504 Plasma cholinesterase level of Ethiopian farm workers exposed to chemical pesticide
Meng_2005_Sheng.Wu.Gong.Cheng.Xue.Bao_21_425 [Synthesis of diacylglycerol using immoblized regiospecific lipase in continuously operated fixed bed reactors]
Merkel_2005_J.Clin.Invest_115_2694 Give me A5 for lipoprotein hydrolysis!
Millitzer_2005_Biotechnol.Bioeng_92_789 Process modeling of in situ-adsorption of a bacterial lipase
Mis_2005_Hum.Exp.Toxicol_24_543 Colocalization of acetylcholinesterase, butyrylcholinesterase and choline acetyltransferase in rat spinal cord
Mis_2005_Chem.Biol.Interact_157-158_29 Expression and distribution of acetylcholinesterase among the cellular components of the neuromuscular junction formed in human myotube in vitro
Miyashita_2005_Curr.Med.Chem.Cardiovasc.Hematol.Agents_3_377 Clinical determination of the severity of metabolic syndrome: preheparin lipoprotein lipase mass as a new marker of metabolic syndrome
Monkemuller_2005_J.Gastroenterol.Hepatol_20_1667 Biochemical analysis of pancreatic fluid collections predicts bacterial infection
Moore_2005_J.Biol.Chem_280_43109 Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase
Moreira-Santos_2005_Environ.Toxicol.Chem_24_2234 Short-term sublethal (sediment and aquatic roots of floating macrophytes) assays with a tropical chironomid based on postexposure feeding and biomarkers
Moretto_2005_Chem.Biol.Interact_157-158_285 Peripheral nerve esterases and the promotion of organophosphate-induced neuropathy in hens
Morgado_2005_Ann.Nutr.Metab_49_397 Comparative effect of fish oil feeding and other dietary fatty acids on plasma lipoproteins, biliary lipids, and hepatic expression of proteins involved in reverse cholesterol transport in the rat
Mu_2005_Prog.Lipid.Res_44_430 The metabolism of structured triacylglycerols
Muggleton_2005_J.Psychopharmacol_19_455 A long-term study of the effects of diazinon on sleep, the electrocorticogram and cognitive behaviour in common marmosets
Mula-Abed_2005_Saudi.Med.J_26_1158\; author reply 1158 Biochemical analysis of serum pancreatic amylase and lipase enzymes in patients with type 1 and type 2 diabetes mellitus
Mungenast_2005_J.Neuroendocrinol_17_208 Expression of three gene families encoding cell-cell communication molecules in the prepubertal nonhuman primate hypothalamus
Nakajima_2005_Biosci.Biotechnol.Biochem_69_2009 An isozyme of earthworm serine proteases acts on hydrolysis of triacylglycerol
Nguyen_2005_Arch.Pharm.Res_28_1073 Mutant presenilin 2 increases acetylcholinesterase activity in neuronal cells
Nguyen-Huu_2005_Anesthesiology_103_788 Cholinesterases and the resistance of the mouse diaphragm to the effect of tubocurarine
Nierman_2005_Arterioscler.Thromb.Vasc.Biol_25_2410 Enhanced conversion of triglyceride-rich lipoproteins and increased low-density lipoprotein removal in LPLS447X carriers
Nierman_2005_Metabolism_54_1499 Carriers of the frequent lipoprotein lipase S447X variant exhibit enhanced postprandial apoprotein B-48 clearance
Nieto-Ceron_2005_J.Neurochem_95_1035 Muscular dystrophy by merosin deficiency decreases acetylcholinesterase activity in thymus of Lama2dy mice
Noel_2005_Bioprocess.Biosyst.Eng_27_375 Polyhydric alcohol protective effect on Rhizomucor miehei lipase deactivation enhanced by pressure and temperature treatment
Nunes_2005_J.Enzyme.Inhib.Med.Chem_20_369 Characterization and use of the total head soluble cholinesterases from mosquitofish (Gambusia holbrooki) for screening of anticholinesterase activity
Ohnuma_2005_Mol.Cell.Biol_25_7743 CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells
Omori_2005_J.Biosci.Bioeng_100_323 Active lactonizing lipase (LipL) efficiently overproduced by Pseudomonas strains as heterologous expression hosts
Onder_2005_Br.J.Psychiatry_187_450 Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial
O'Neill_2005_Drug.Discov.Today_10_1132 UK government guidance on Alzheimer's drugs postponed
Onganer_2005_J.Membr.Biol_204_67 Small-cell lung cancer (human): potentiation of endocytic membrane activity by voltage-gated Na(+) channel expression in vitro
Ozmen_2005_Plast.Reconstr.Surg_116_1823 Is pseudocholinesterase elevation a risk for surgery?
Pal_2005_J.Indian.Med.Assoc_103_168 Management of neurodegenerative disorders: Parkinson's disease and Alzheimer's disease
Pancrazi_2005_Presse.Med_34_667 [Treatment of the psychological and behavioural disorders of Alzheimer's disease]
Panzera_2005_Transplant.Proc_37_2456 Solutions for organ perfusion and storage: haemorheologic aspects
Parton_2005_Curr.Opin.Neurol_18_675 Neuropharmacological modulation of cognitive deficits after brain damage
Parvulescu_2005_Chem.Commun.(Camb)__5307 Efficient dynamic kinetic resolution of secondary amines with Pd on alkaline earth salts and a lipase
Pereira_2005_Clin.Exp.Metastasis_22_285 Invasion-associated MMP-2 and MMP-9 are up-regulated intracellularly in concert with apoptosis linked to melanoma cell detachment
Perez-Gilabert_2005_J.Agric.Food.Chem_53_5754 Characterization and histochemical localization of nonspecific esterase from ascocarps of desert truffle (Terfezia claveryi Chatin)
Perrier_2005_J.Neurochem_94_629 The readthrough variant of acetylcholinesterase remains very minor after heat shock, organophosphate inhibition and stress, in cell culture and in vivo
Petralia_2005_Mol.Cell.Neurosci_29_436 Ontogeny of postsynaptic density proteins at glutamatergic synapses
Petroianu_2005_J.Appl.Toxicol_25_562 Weak inhibitors protect cholinesterases from strong inhibitors (paraoxon): in vitro effect of tiapride
Picha_2005_J.Enzyme.Inhib.Med.Chem_20_233 A new group of monoquaternary reactivators of acetylcholinesterase inhibited by nerve agents
Pilegaard_2005_Metabolism_54_1048 Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise
Placencia_2005_J.Environ.Sci.Health.B_40_761 Inhibitory effects on esterase enzymes buche and ache in rainbow trout (Oncorhyncus mykiss) produced by the slow release insecticide chitosan diethyl phosphate
Plamboeck_2005_Diabetologia_48_1882 Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
Plaza_2005_Ann.Diagn.Pathol_9_298 Lymphoplasmacytic sclerosing pancreatitis
Porsgaard_2005_J.Nutr_135_1705 Differences in the intramolecular structure of structured oils do not affect pancreatic lipase activity in vitro or the absorption by rats of (n-3) fatty acids
Potyk_2005_South.Med.J_98_628 Treatments for Alzheimer disease
Poulsen_2005_Biochemistry_44_11574 Quantization of pH: evidence for acidic activity of triglyceride lipases
Rader_2005_Arterioscler.Thromb.Vasc.Biol_25_2018 Gain-of-function mutations and therapeutic implications: lipoprotein lipase S447X to the rescue
Rakonczay_2005_Chem.Biol.Interact_157-158_233 Peripheral cholinergic disturbances in Alzheimer's disease
Ramkumar_2005_J.Basic.Clin.Physiol.Pharmacol_16_17 Modulation of impaired cholinesterase activity in experimental diabetes: effect of Gymnema montanum leaf extract
Rao_2005_J.Environ.Sci.Health.B_40_813 Sublethal effects of monocrotophos on locomotor behavior and gill architecture of the mosquito fish, Gambusia affinis
Rasool_2005_FEMS.Microbiol.Lett_249_113 Molecular cloning of enantioselective ester hydrolase from Bacillus pumilus DBRL-191
Recio_2005_Environ.Health.Perspect_113_1160 Pesticide exposure alters follicle-stimulating hormone levels in Mexican agricultural workers
Reumann_2005_Mol.Membr.Biol_22_73 Evolution of the general protein import pathway of plastids (review)
Reyes-Duarte_2005_Angew.Chem.Int.Ed.Engl_44_7553 Conversion of a carboxylesterase into a triacylglycerol lipase by a random mutation
Rhodes_2005_J.Neuroendocrinol_17_817 Pituitary-adrenal responses to cholinergic stimulation and acute mild stress are differentially elevated in male and female M(2) muscarinic receptor knockout mice
Ribas_2005_Biochim.Biophys.Acta_1737_130 Paradoxical exacerbation of combined hyperlipidemia in human apolipoprotein A-II transgenic mice treated with fenofibrate
Ridder_2005_Ned.Tijdschr.Geneeskd_149_1701 [Physostigmine for the immediate treatment of a patient with the central anticholinergic syndrome induced by cocaine cut with atropine]
Rider_2005_Toxicol.Sci_87_520 An integrated addition and interaction model for assessing toxicity of chemical mixtures
Riepe_2005_Eur.J.Neurol_12 Suppl 3_3 Cholinergic treatment: what are the early neuropathological targets?
Ristic_2005_Diabetes.Obes.Metab_7_692 Improved glycaemic control with dipeptidyl peptidase-4 inhibition in patients with type 2 diabetes: vildagliptin (LAF237) dose response
Roberts_2005_Anaesth.Intensive.Care_33_469 Experiences of anticholinesterase pesticide poisonings in an Australian tertiary hospital
Rodriguez-Franco_2005_Bioorg.Med.Chem_13_6795 Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase
Roepstorff_2005_Exerc.Sport.Sci.Rev_33_182 Intramuscular triacylglycerol in energy metabolism during exercise in humans
Roman_2005_Dement.Geriatr.Cogn.Disord_20_338 Donepezil in vascular dementia: combined analysis of two large-scale clinical trials
Rosenberry_2005_Chem.Biol.Interact_157-158_181 Interactions between the peripheral site and the acylation site in acetylcholinesterase
Ross_2005_Arterioscler.Thromb.Vasc.Biol_25_2143 Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation
Rotella_2005_J.Endocrinol.Invest_28_746 Glucagon-like peptide 1 (GLP-1) and metabolic diseases
Rusnak_2005_Biotechnol.Lett_27_743 The putative lipase, AF1763, from Archaeoglobus fulgidusis is a carboxylesterase with a very high pH optimum
Sabally_2005_Appl.Biochem.Biotechnol_127_17 Lipase-catalyzed esterification of selected phenolic acids with linolenyl alcohols in organic solvent media
Sabbagh_2005_J.Alzheimers.Dis_7_285 The use of memantine in dementia with Lewy bodies
Sahin_2005_Int.J.Biol.Macromol_37_148 A novel matrix for the immobilization of acetylcholinesterase
Sahin_2005_J.Agric.Food.Chem_53_5779 Lipase-catalyzed acidolysis of tripalmitin with hazelnut oil fatty acids and stearic acid to produce human milk fat substitutes
Saiki_2005_J.Atheroscler.Thromb_12_163 Pitavastatin enhanced lipoprotein lipase expression in 3T3-L1 preadipocytes
Sakinc_2005_Infect.Immun_73_6419 The surface-associated protein of Staphylococcus saprophyticus is a lipase
Saranteas_2005_Eur.J.Anaesthesiol_22_875 Ketamine-induced changes in metabolic and endocrine parameters of normal and 2-kidney 1-clip rats
Saxena_2005_Chem.Biol.Interact_157-158_199 Human serum butyrylcholinesterase: in vitro and in vivo stability, pharmacokinetics, and safety in mice
Scarmeas_2005_Arch.Neurol_62_1601 Delusions and hallucinations are associated with worse outcome in Alzheimer disease
Schindler_2005_Eur.J.Neurol_12 Suppl 3_17 Dementia with cerebrovascular disease: the benefits of early treatment
Schmidt_2005_Curr.Med.Chem_12_1677 Drug development and PET-diagnostics for Alzheimer's disease
Schroeder_2005_Scand.J.Work.Environ.Health_31 Suppl 1_26 Metabolic susceptibility to agricultural pesticides and non-Hodgkin's lymphoma
Schulz_2005_J.Neurochem_94_970 Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion
Sedo_2005_Arthritis.Res.Ther_7_253 Dipeptidyl peptidase IV activity and\/or structure homologs: contributing factors in the pathogenesis of rheumatoid arthritis?
Selkirk_2005_Chem.Biol.Interact_157-158_263 Nematode acetylcholinesterases are encoded by multiple genes and perform non-overlapping functions
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Sousa-Polezzi_2005_Genetica_125_43 Genetic variation along time in a Brazilian population of Aedes aegypti (Diptera: Culicidae), detected by changes in the esterase patterns
Souza_2005_Biomarkers_10_376 Prenatal exposure to pesticides: analysis of human placental acetylcholinesterase, glutathione S-transferase and catalase as biomarkers of effect
Sridhar_2005_Lipids.Health.Dis_4_18 Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach
Stamler_2005_J.Toxicol.Environ.Health.A_68_1413 Biochemical markers of neurotoxicity in wildlife and human populations: considerations for method development
Stojan_2005_Chem.Biol.Interact_157-158_173 Rational polynomial equation helps to select among homeomorphic kinetic models for cholinesterase reaction mechanism
Suprun_2005_Anal.Bioanal.Chem_383_597 Acetylcholinesterase sensor based on screen-printed carbon electrode modified with prussian blue
Suzuki_2005_J.Agric.Food.Chem_53_8400 Effects of lipase, lipoxygenase, peroxidase, and rutin on quality deteriorations in buckwheat flour
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Tadiboyina_2005_Lipids.Health.Dis_4_26 Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease
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Tyminski_2005_Cancer.Res_65_6850 Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan
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da Fonseca Ade_2005_Pharmacol.Biochem.Behav_81_551 Nicotine pretreatment diminished physostigmine-induced tremor in rats
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Fernandes_2005_Neuropharmacol_49_564 The lateral septal area is involved in the pressor pathway activated by microinjection of norepinephrine into the rat brain cingulate cortex
Galeotti_2005_Behav.Brain.Res_164_165 Ryanodine receptors are involved in muscarinic antinociception in mice
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Greenfield_2005_Chem.Biol.Interact_157-158_211 A peptide derived from acetylcholinesterase is a pivotal signalling molecule in neurodegeneration
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Jager_2005_Environ.Sci.Technol_39_8307 Modeling receptor kinetics in the analysis of survival data for organophosphorus pesticides
Ji_2005_J.Environ.Sci.(China)_17_256 Neurotransmitter level changes in domestic ducks (Shaoxing duck) growing up in typical mercury contaminated area in China
Johnston_2005_J.Hist.Neurosci_14_121 The contribution of Dr. Mary Walker towards myasthenia gravis and periodic paralysis whilst working in poor law hospitals in London
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Kircher_2005_Am.J.Geriatr.Psychiatry_13_1006 Cortical activation during cholinesterase-inhibitor treatment in Alzheimer disease: preliminary findings from a pharmaco-fMRI study
Kogut_2005_Pharmacotherapy_25_1729 Decreased persistence to cholinesterase inhibitor therapy with concomitant use of drugs that can impair cognition
Kronman_2005_Chem.Biol.Interact_157-158_51 Host-regulated disposition of mammalian AChEs
Lai_2005_Bioelectromagnetics_26_81 Comment on Radial arm maze performance of rats following repeated low level microwave radiation exposure
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Longobardi_2005_J.Agric.Food.Chem_53_9389 Use of electrochemical biosensor and gas chromatography for determination of dichlorvos in wheat
Meggs_2005_Clin.Toxicol.(Phila)_43_383 Fallacies in the refutation of causality
Mohapel_2005_Neurobiol.Aging_26_939 Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning
Montero-Barrientos_2005_Int.J.Syst.Evol.Microbiol_55_2491 Terrabacter terrae sp. nov., a novel actinomycete isolated from soil in Spain
Oakeshott_2005_Chem.Biol.Interact_157-158_269 Comparing the organophosphorus and carbamate insecticide resistance mutations in cholin- and carboxyl-esterases
Pearce_2005_Eur.Neurol_53_51 Mary Broadfoot Walker (1888-1974): a historic discovery in myasthenia gravis
Racchi_2005_Chem.Biol.Interact_157-158_335 Role of acetylcholinesterase inhibitors in the regulation of amyloid beta precursor protein (AbetaPP) metabolism
Renault_2005_Chem.Biol.Interact_157-158_339 New friendly tools for users of ESTHER, the database of the alpha\/beta-hydrolase fold superfamily of proteins
Rendon-von_2005_Chemosphere_58_627 In vivo evaluation of three biomarkers in the mosquitofish (Gambusia yucatana) exposed to pesticides
Salmon_2005_Chem.Biol.Interact_157-158_105 Muscarinic modulations of neuronal anticholinesterase responses
Svobodova_2005_Ann.N.Y.Acad.Sci_1048_355 Allosteric modulation of the nicotinic acetylcholine receptor by physostigmine
Valette_2005_Synapse_56_217 Acute effects of physostigmine and galantamine on the binding of [18F]fluoro-A-85380: a PET study in monkeys
Wang_2005_Int.J.Pharm_290_25 Skin permeation of physostigmine from fatty acids-based formulations: evaluating the choice of solvent
Yang_2005_Hepatobiliary.Pancreat.Dis.Int_4_600 Lipase and pancreatic amylase activities in diagnosis of acute pancreatitis in patients with hyperamylasemia
Zhukovskaia_2005_Izv.Akad.Nauk.Ser.Biol__625 [Study of genetic diversity of earthworm Lumbricus rubellus Hoff. (Oligochaeta, Lumbricidae)]
Arner_2005_Best.Pract.Res.Clin.Endocrinol.Metab_19_471 Human fat cell lipolysis: biochemistry, regulation and clinical role
Avila-Gonzalez_2005_J.Biosci.Bioeng_100_423 Lipase-catalyzed preparation of S-propranolol in presence of hydroxypropyl beta-cyclodextrins
Bartorelli_2005_Curr.Med.Res.Opin_21_1809 Effects of switching from an AChE inhibitor to a dual AChE-BuChE inhibitor in patients with Alzheimer's disease
Bartosova_2005_Int.J.Toxicol_24_399 Bispyridinium oximes as antidotal treatment of cyclosarin poisoning-in vitro and in vivo testing
Becher_2005_J.Nat.Prod_68_1793 Nostocarboline: isolation and synthesis of a new cholinesterase inhibitor from Nostoc 78-12A
Berg_2005_Acta.Radiol_46_815 Iodinated radiographic contrast media possess antioxidant properties in vitro
Beyer_2005_Ann.N.Y.Acad.Sci_1057_260 Age at onset: an essential variable for the definition of genetic risk factors for sporadic Alzheimer's disease
Bhanji_2005_J.Neuropsychiatry.Clin.Neurosci_17_552 Emergent complications following donepezil switchover to galantamine in three cases of dementia with Lewy bodies
Bharavi_2005_Indian.J.Physiol.Pharmacol_49_337 Effect of anticholinesterase compound phosalone on blood-brain barrier (BBB) permeability
Birk_2005_Br.J.Nutr_94_885 Lactation decreases pancreatic lipase mRNA level in the rat
Bombois_2005_Rev.Prat_55_1913 [Treatment of Alzheimer's disease]
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Bottino_2005_Clin.Rehabil_19_861 Cognitive rehabilitation combined with drug treatment in Alzheimer's disease patients: a pilot study
Braga_2005_J.Med.Entomol_42_830 Effectiveness of methoprene, an insect growth regulator, against temephos-resistant Aedes aegypti populations from different Brazilian localities, under laboratory conditions
Brvar_2005_Clin.Toxicol.(Phila)_43_891 Poisoning with rivastigmine
Caltagirone_2005_Drugs.Aging_22 Suppl 1_1 Guidelines for the treatment of Alzheimer's disease from the Italian Association of Psychogeriatrics
Chandrasekera_2005_Bull.Environ.Contam.Toxicol_75_1228 Response of brain and liver cholinesterases of Nile tilapia, Oreochromis niloticus, to single and multiple exposures of chlorpyrifos and carbosulfan
Chang_2005_J.Agric.Food.Chem_53_9841 Monitoring lipase-catalyzed interesterification for bulky fat modification with FT-IR\/NIR spectroscopy
Chitano_2005_Can.J.Physiol.Pharmacol_83_833 Mechanisms of airway smooth muscle relaxation during maturation
Clerici_2005_Neurol.Sci_26_358 Dementia with Lewy bodies with supranuclear gaze palsy: a matter of diagnosis
Costa_2005_Genet.Mol.Res_4_616 Hydrolases in the hypopharyngeal glands of workers of Scaptotrigona postica and Apis mellifera (Hymenoptera, Apinae)
Dartigues_2005_Rev.Neurol.(Paris)_161_957 [Prescription of cholinesterase inhibitors in Alzheimer's disease in France in 2000-2001: an assessment of compliance with national guidelines for diagnosis and follow-up]
Dharmani_2005_Rev.Environ.Health_20_215 Epidemiology of acute organophosphate poisoning in hospital emergency room patients
Dippenaar_2005_S.Afr.Med.J_95_678 Paediatric organophosphate poisoning--a rural hospital experience
Falcocchio_2005_Can.J.Microbiol_51_753 Identification of a carboxylesterase-producing Rhodococcus soil isolate
Fickers_2005_Biotechnol.Lett_27_1751 Methyl oleate modulates LIP2 expression in the lipolytic yeast Yarrowia lipolytica
Fu_2005_Brain.Res_1066_10 Antisense inhibition of acetylcholinesterase gene expression for treating cognition deficit in Alzheimer's disease model mice
Gallwitz_2005_Treat.Endocrinol_4_361 Glucagon-like peptide-1-based therapies for the treatment of type 2 diabetes mellitus
Garcia_2005_Appl.Biochem.Biotechnol_127_69 Application of design-of-experiments procedures to optimize efficiently pretreatment of lipase for use in a nonaqueous reaction
Gaus_2005_Methods.Inf.Med_44_697 Identification of adverse drug reactions by evaluation of a prescription database, demonstrated for risk of bleeding
Geldmacher_2005_Manag.Care_14_44 The cost benefit to health plans of pharmacotherapy for Alzheimer's disease
Gottsche_2005_Lipids_40_1273 Lipolysis of different oils using crude enzyme isolate from the intestinal tract of rainbow trout, Oncorhynchus mykiss
Green_2005_Pharmacoeconomics_23_1271 Modelling the cost effectiveness of cholinesterase inhibitors in the management of mild to moderately severe Alzheimer's disease
Guez_2005_Ecotoxicology_14_431 Methyl parathion modifies foraging behaviour in honeybees (Apis mellifera)
Guo_2005_J.Am.Chem.Soc_127_15662 A general acid-base mechanism for the stabilization of a tetrahedral adduct in a serine-carboxyl peptidase: a computational study
Guo_2005_Obes.Res_13_2081 Muscle type-dependent responses to insulin in intramyocellular triglyceride turnover in obese rats
Haug_2005_Neurochem.Res_30_1511 Effects on cholinergic markers in rat brain and blood after short and prolonged administration of donepezil
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Inami_2005_J.Antibiot.(Tokyo)_58_640 FR177391, a new anti-hyperlipidemic agent from Serratia. II. Pharmacological activity of FR177391
Inamoto_2005_Int.J.Hematol_82_362 Severe hypercholesterolemia associated with decreased hepatic triglyceride lipase activity and pseudohyponatremia in patients after allogeneic stem cell transplantation
Jayaprakash_2005_Dis.Aquat.Organ_68_39 A marine bacterium, Micrococcus MCCB 104, antagonistic to vibrios in prawn larval rearing systems
Kim_2005_Clin.Neurol.Neurosurg_108_97 A case with cholinesterase inhibitor responsive asymmetric posterior cortical atrophy
Kim_2005_Water.Sci.Technol_52_51 Effect of enzymatic pretreatment on solubilization and volatile fatty acid production in fermentation of food waste
Kissling_2005_Phytother.Res_19_984 Bio-guided isolation of cholinesterase inhibitors from the bulbs of Crinum x powellii
Kojima_2005_Alcohol.Clin.Exp.Res_29_259S Difference and similarity between non-alcoholic steatohepatitis and alcoholic liver disease
Komersova_2005_Chem.Biol.Interact_157-158_387 Kinetics of hydrolysis of acetylthiocholine and acetylcholine by cholinesterases
Kusunoki_2005_Metabolism_54_1587 NO-1886 (ibrolipim), a lipoprotein lipase activator, increases the expression of uncoupling protein 3 in skeletal muscle and suppresses fat accumulation in high-fat diet-induced obesity in rats
Kventsel_2005_Clin.Toxicol.(Phila)_43_877 Scopolamine treatment for severe extra-pyramidal signs following organophosphate (chlorpyrifos) ingestion
Lahiri_2005_Ann.N.Y.Acad.Sci_1056_430 Amyloid, cholinesterase, melatonin, and metals and their roles in aging and neurodegenerative diseases
Lei_2005_Environ.Sci.Technol_39_8853 Highly sensitive and selective amperometric microbial biosensor for direct determination of p-nitrophenyl-substituted organophosphate nerve agents
Li_2005_Chem.Biol.Interact_157-158_383 Identification of organophosphate-reactive proteins by tandem mass spectrometry
Ligresti_2005_Curr.Drug.Targets.CNS.Neurol.Disord_4_615 Endocannabinoid metabolic pathways and enzymes
Linton_2005_J.Gerontol.Nurs_31_4 The benefits of cholinesterase inhibitors: managing the behavioral and neuropsychiatric symptoms of Alzheimer's disease
Luo_2005_Chem.Biol.Interact_157-158_393 Species-related differences in the oxime-induced reactivation of organophosphate-inhibited acetylcholinesterases
Maruyama_2005_Arch.Histol.Cytol_68_267 Neurotrophin-4\/5-depletion induces a delay in maturation of the periodontal Ruffini endings in mice
Mazza_2005_Clin.Ter_156_203 [Efficacy of adjunctive donepezil for cognitive impairments in patients with schizophrenia]
McDougall_2005_Biofactors_23_189 The inhibitory effects of berry polyphenols on digestive enzymes
Meier_2005_J.Med.Chem_48_8079 cycloSal-PMEA and cycloAmb-PMEA: potentially new phosphonate prodrugs based on the cycloSal-pronucleotide approach
Menendez-Gonzalez_2005_J.Alzheimers.Dis_8_289 Exacerbation of Lewy bodies dementia due to memantine
Miller_2005_J.Med.Entomol_42_912 First report of organophosphate-resistant Boophilus microplus (Acari: Ixodidae) within the United States
Mitra_2005_Langmuir_21_12115 Geometric constraints at the surfactant headgroup: effect on lipase activity in cationic reverse micelles
Musilek_2005_J.Enzyme.Inhib.Med.Chem_20_409 Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase
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Niederhofer_2005_J.Atten.Disord_9_382 Serum cholinesterase levels elevated in patients suffering from ADHD
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Nojima_2005_Anal.Sci_21_1437 Genotyping of the human lipoprotein lipase gene by ferrocenylnaphthalene diimide-based electrochemical hybridization assay
Ogawa_2005_Clin.Exp.Pharmacol.Physiol_32_1104 Beneficial effect of laserpitin, a coumarin compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats
Ouedraogo_2005_Bull.Soc.Pathol.Exot_98_406 [Susceptibility of Culex quinquefasciatus to insecticides in Bobo Dioulasso, Burkina Faso]
Padron-Sanz_2005_J.AOAC.Int_88_1485 An approach to the application of microwave-assisted micellar extraction and liquid chromatography with ultraviolet detection to the extraction and determination of organophosphorus pesticides in tomato samples
Patani_2005_Pharm.Dev.Technol_10_525 A potent and selective tacrine analog--biomembrane permeation and physicochemical characterization
Paul_2005_Clin.Toxicol.(Phila)_43_867 Intermediate syndrome following carbamate poisoning
Pietsch_2005_J.Med.Chem_48_8270 Synthesis of tricyclic 1,3-oxazin-4-ones and kinetic analysis of cholesterol esterase and acetylcholinesterase inhibition
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Puffenbarger_2005_Curr.Drug.Targets.CNS.Neurol.Disord_4_625 Molecular biology of the enzymes that degrade endocannabinoids
Quitadamo_2005_Eur.J.Neurosci_22_2723 Activation and desensitization of neuronal nicotinic receptors modulate glutamatergic transmission on neonatal rat hypoglossal motoneurons
Rascher_2005_Appl.Environ.Microbiol_71_4862 Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption
Ren_2005_Dysphagia_20_182 Intrinsic properties of the adult human mylohyoid muscle: neural organization, fiber-type distribution, and myosin heavy chain expression
Rip_2005_Hum.Gene.Ther_16_1276 Gene therapy for lipoprotein lipase deficiency: working toward clinical application
Rodriguez_2005_J.Am.Mosq.Control.Assoc_21_437 Pyrethroid insecticide-resistant strain of Aedes aegypti from Cuba induced by deltamethrin selection
Rollinger_2005_Planta.Med_71_1040 New insights into the acetylcholinesterase inhibitory activity of Lycopodium clavatum
Rollinger_2005_Curr.Drug.Discov.Technol_2_185 Application of the in combo screening approach for the discovery of non-alkaloid acetylcholinesterase inhibitors from Cichorium intybus
Romani_2005_Environ.Toxicol.Chem_24_2879 Effects of chlorpyrifos on the catalytic efficiency and expression level of acetylcholinesterases in the bivalve mollusk Scapharca inaequivalvis
Rozengart_2005_Dokl.Biochem.Biophys_405_450 Conformational characteristics of the structure of acetylcholine amide derivatives and the specificity of their action as reversible inhibitors of cholinesterases of different animals
Rozengart_2005_Dokl.Biochem.Biophys_405_400 Element-onium silatran derivatives as reversible inhibitors of cholinesterases of various origin
Saburkina_2005_Medicina.(Kaunas)_41_936 [Distribution of the epicardiac neural ganglia in human fetuses of different age]
Saeed_2005_Pol.J.Microbiol_54_233 Purification and characterization of two extracellular lipases from Pseudomonas aeruginosa Ps-x
Satar_2005_Mt.Sinai.J.Med_72_389 Carbofuran poisoning among farm workers
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Senapati_2005_J.Med.Chem_48_8155 Induced fit in mouse acetylcholinesterase upon binding a femtomolar inhibitor: a molecular dynamics study
Slaughter_2005_Cells.Tissues.Organs_181_51 Neuromuscular organization of the superior longitudinalis muscle in the human tongue. 1. Motor endplate morphology and muscle fiber architecture
Sobow_2005_Folia.Neuropathol_43_340 Short-term treatment with rivastigmine and plasma levels of Abeta peptides in Alzheimer's disease
Solntseva_2005_Dokl.Biol.Sci_405_417 Potassium channel modulation by acetylcholinesterase inhibitor donepezil
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Stepankova_2005_Z.Naturforsch.C_60_943 Two new methods monitoring kinetics of hydrolysis of acetylcholine and acetylthiocholine
Suma_2005_J.Anal.Toxicol_29_728 Simple liquid chromatographic method for the rapid and simultaneous determination of propoxur and its major metabolite isopropoxy phenol in rat blood and urine using solid-phase extraction
Tahara_2005_Water.Res_39_5112 Use of cholinesterase activity as an indicator for the effects of combinations of organophosphorus pesticides in water from environmental sources
Tonduli_2005_Chem.Biol.Interact_157-158_426 An ex vivo approach for the evaluation of reversible inhibitors as potential pretreatments against organophosphate toxicity
Turecky_2005_Bratisl.Lek.Listy_106_266 Serum cholinesterase activity and proteosynthetic function of liver in patients with diabetes mellitus
Wang_2005_Zhongguo.Zhong.Xi.Yi.Jie.He.Za.Zhi_25_955 [Progress of study on brain protective effect and mechanism of Polygonum multiflorum]
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Waters_2005_J.Psychopharmacol_19_149 Assessment of modafinil on attentional processes in a five-choice serial reaction time test in the rat
Wilson_2005_Chem.Biol.Interact_157-158_253 Monitoring cholinesterases to detect pesticide exposure
Yoder_2005_Hippocampus_15_381 Involvement of GABAergic and cholinergic medial septal neurons in hippocampal theta rhythm
Yoshida_2005_Intern.Med_44_1157 Risk factors for hospital-acquired bacteremia
Young_2005_Adv.Pharmacol_52_123 Effects on digestive secretions
Zarrindast_2005_Pharmacol.Biochem.Behav_82_1 Role of the cholinergic system in the rat basolateral amygdala on morphine-induced conditioned place preference
Zhan_2005_Biophys.J_89_3863 Catalytic mechanism and energy barriers for butyrylcholinesterase-catalyzed hydrolysis of cocaine
Zhang_2005_PLoS.Comput.Biol_1_e62 The association of tetrameric acetylcholinesterase with ColQ tail: a block normal mode analysis
Zhu_2005_Ann.Chim_95_877 Molecularly imprinted polymer for monocrotophos and its binding characteristics for organophosphorus pesticides
Zimmermann_2005_Drugs.Aging_22 Suppl 1_27 Molecular rationale for the pharmacological treatment of Alzheimer's disease
Zivkovic_2005_Am.J.Electroneurodiagnostic.Technol_45_248 Use of repetitive nerve stimulation in the evaluation of neuromuscular junction disorders
Amaroli_2005_Chem.Biol.Interact_157-158_355 Effects of time-variant extremely low-frequency (ELF) electromagnetic fields (EMF) on cholinesterase activity in Dictyostelium discoideum (Protista)
Bartosova_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_425 Effectivity of new acetylcholinesterase reactivators in treatment of cyclosarin poisoning in mice and rats
Bodur_2005_Chem.Biol.Interact_157-158_375 The effects of indole-3-acetic acid on human and horse serum butyrylcholinesterase
Buhler_2005_Chembiochem_6_711 Inversion of stereoselectivity by applying mutants of the hydroxynitrile lyase from Manihot esculenta
Bui_2005_Chem.Biol.Interact_157-158_357 Acetylcholinesterase: pivotal roles of its long omega loop (Cys69-Cys96) in regulating substrate binding
Carlson_2005_Consult.Pharm_20_584 Evaluation of demographics and medication use in patients with dementia in assisted living and skilled nursing facilities
Chuiko_2005_Chem.Biol.Interact_157-158_365 Acetylcholinesterase and butyrylcholinesterase of freshwater teleosts
Cusack_2005_Chem.Biol.Interact_157-158_370 A novel strategy for protection against organophosphate toxicity: Evolution of cyclic inhibitors with high affinity for the acetylcholinesterase peripheral site
Dong_2005_Chem.Biol.Interact_157-158_373 Acetylcholinesterase genes and insecticide resistance in aphids
Efrati_2005_Genome_48_347 Molecular mapping of the chlorophyll retainer (cl) mutation in pepper (Capsicum spp.) and screening for candidate genes using tomato ESTs homologous to structural genes of the chlorophyll catabolism pathway
Ehrt_2005_Curr.Opin.Psychiatry_18_335 Psychiatric aspects of Parkinson's disease
Espinosa_2005_Chem.Biol.Interact_157-158_379 Effects of succinic acid derivatives on ex vivo acetylcholinesterase activity
Furegati_2005_Chem.Biol.Interact_157-158_415 Decalin-type acetylcholine-mimetic organophosphates as inhibitors of acetylcholinesterase
Furegati_2005_Chem.Biol.Interact_157-158_418 The stereochemistry of the inhibition of acetylcholinesterase with acetylcholine-mimetic 7-aza-2,4-dioxaphosphadecalins
Gabryelewicz_2005_Wiad.Lek_58_528 [Alzheimer's disease therapy--theory and practice]
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Kovarik_2005_Chem.Biol.Interact_157-158_388 Acetylcholinesterase mutants: oxime-assisted catalytic scavengers of organophosphonates
Kuca_2005_Chem.Biol.Interact_157-158_367 Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo
Kuca_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_429 Strategy for the development of new acetylcholinesterase reactivators - antidotes used for treatment of nerve agent poisonings
Leentjens_2005_Curr.Opin.Psychiatry_18_325 Delirium in elderly people: an update
Lepienski_2005_Chem.Biol.Interact_157-158_374 Variant K of butyrylcholinesterase and types 1 and 2 of diabetes mellitus
Lessenger_2005_J.Agromedicine_10_49 Fifteen years of experience in cholinesterase monitoring of insecticide applicators
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Mann_2005_Consult.Pharm_20_306 An assessment of the diagnosis and management of dementia in nursing homes
Martinez-Moreno_2005_Chem.Biol.Interact_157-158_359 Acetylcholinesterase biogenesis is impaired in lung cancer tissues
Molochkina_2005_Chem.Biol.Interact_157-158_401 H2O2 modifies membrane structure and activity of acetylcholinesterase
Montenegro_2005_Chem.Biol.Interact_157-158_429 Cholinesterase activity and enzyme components in healthy and cancerous human colorectal sections
Morakchi_2005_Commun.Agric.Appl.Biol.Sci_70_843 Effects of a neonicotinoid insecticide (acetamiprid) on acetylcholinesterase activity and cuticular hydrocarbons profil in German cockroaches
Muralidharan_2005_Chem.Biol.Interact_157-158_406 Characterizing pea acetylcholinesterase
Nachon_2005_Chem.Biol.Interact_157-158_408 Structural data on the aging of diethylphosphoryl-butyrylcholinesterase
Nambiar_2005_Chem.Biol.Interact_157-158_409 Transcriptional induction of cholinesterase expression and protection against chemical warfare nerve agents
Olivera_2005_Chem.Biol.Interact_157-158_410 Acetylcholinesterase effects on glutamate receptors
Patlolla_2005_Int.J.Environ.Res.Public.Health_2_80 Serum acetyl cholinesterase as a biomarker of arsenic induced neurotoxicity in sprague-dawley rats
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Pezzementi_2005_Chem.Biol.Interact_157-158_413 Ligand-induced conformational changes in residues flanking the active site gorge of acetylcholinesterase
Rawls_2005_Consult.Pharm_20_592 Donepezil in more advanced Alzheimer's disease
Sanchez_2005_Chem.Biol.Interact_157-158_431 Muscular dystrophy with laminin deficiency decreases acetylcholinesterase activity in thymus of dystrophic Lama2dy mice
Sato_2005_Appl.Environ.Microbiol_71_4372 Two rhizobial strains, Mesorhizobium loti MAFF303099 and Bradyrhizobium japonicum USDA110, encode haloalkane dehalogenases with novel structures and substrate specificities
Selkirk_2005_Parasitol_131 Suppl_S3 Functional genomics of nematode acetylcholinesterases
Simeon-Rudolf_2005_Chem.Biol.Interact_157-158_420 Preparation of enantiomers of quinuclidin-3-Ol derivatives and their interactions with human cholinesterases
Sinko_2005_Chem.Biol.Interact_157-158_421 Structure-inhibition relationships in the interaction of butyrylcholinesterase with bambuterol, haloxon and their leaving groups
Sun_2005_Chem.Biol.Interact_157-158_428 Safety and pharmacokinetics of human serum butyrylcholinesterase in guinea pigs
Svoboda_2005_Biomed.Pap.Med.Fac.Univ.Palacky.Olomouc.Czech.Repub_149_335 Galantamine antiacetylcholinesterase activity in rat brain influenced by L-carnitine
Turiiski_2005_Folia.Med.(Plovdiv)_47_45 Non-anticholinesterase, non-cholinergic effect of tacrine on gastrointestinal smooth muscle tissues of rat
Wananukul_2005_J.Med.Assoc.Thai_88_1308 The intermediate syndrome as critical sequelae of organophosphate poisoning: the first report of two cases in Thailand
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Bollen_2005_Biophys.Chem_114_181 Protein topology affects the appearance of intermediates during the folding of proteins with a flavodoxin-like fold
Botma_2005_Atherosclerosis_179_61 Sterol-regulatory-element binding protein inhibits upstream stimulatory factor-stimulated hepatic lipase gene expression
Dziekonska-Rynko_2005_Wiad.Parazytol_51_227 Activity of selected hydrolases in excretion-secretion products and extracts of adult Contracaecum rudolphii
Eller_2005_J.Intern.Med_258_344 Hepatic lipase polymorphism and increased risk of peripheral arterial disease
Evron_2005_Neurodegener.Dis_2_16 RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons
Fan_2005_J.Clin.Endocrinol.Metab_90_3786 Hepatic lipase C-480T genotype-dependent benefit from long-term hormone replacement therapy for atherosclerosis progression in postmenopausal women
Figueroa-Espinoza_2005_J.Agric.Food.Chem_53_2779 Phenolic acids enzymatic lipophilization
Janssen_2005_Environ.Microbiol_7_1868 Bacterial degradation of xenobiotic compounds: evolution and distribution of novel enzyme activities
Kepka_2005_J.Chromatogr.A_1075_33 Two-step recovery process for tryptophan tagged cutinase: interfacing aqueous two-phase extraction and hydrophobic interaction chromatography
Lockridge_2005_J.Med.Chem.Biol.Radiol.Def_3_nihms5095 Large scale purification of butyrylcholinesterase from human plasma suitable for injection into monkeys\; A potential new therapeutic for protection against cocaine end nerve agent toxicity
Micaelo_2005_Biophys.J_89_999 Water dependent properties of cutinase in nonaqueous solvents: a computational study of enantioselectivity
Nakayashiki_2005_Fungal.Genet.Biol_42_275 RNA silencing as a tool for exploring gene function in ascomycete fungi
Nord_2005_FEMS.Microbiol.Lett_242_73 Fluorescent detection of beta-lactamase activity in living Escherichia coli cells via esterase supplementation
Ownby_2005_AMIA.Annu.Symp.Proc__1069 Development of an interactive tailored information application to improve patient medication adherence
Pinzani_2005_J.Endocrinol.Invest_28_120 Healthy centenarian subjects: the effect of red wine consumption on liver function tests
Pujol_2005_Br.J.Dermatol_153_838 Erythrokeratoderma variabilis-like ichthyosis in Chanarin-Dorfman syndrome
Rivolta_2005_J.Clin.Endocrinol.Metab_90_3766 A new case of congenital goiter with hypothyroidism caused by a homozygous p.R277X mutation in the exon 7 of the thyroglobulin gene: a mutational hot spot could explain the recurrence of this mutation
Schleinitz_2005_Arch.Dermatol_141_798 Two new mutations of the ABHD5 gene in a new adult case of Chanarin Dorfman syndrome: an uncommon lipid storage disease
Schmidberger_2005_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_61_271 Purification, crystallization and preliminary crystallographic analysis of DehIVa, a dehalogenase from Burkholderia cepacia MBA4
Suarez_2005_Plant.Physiol.Biochem_43_890 Development of real-time PCR (TaqMan) assays for the detection and quantification of Botrytis cinerea in planta
Alexopoulos_2005_Postgrad.Med_Spec No_6 The expert consensus guideline series. Treatment of dementia and its behavioral disturbances. Introduction: methods, commentary, and summary
Ansari_2005_Chem.Biodivers_2_487 Syntheses and biological activities of chalcone and 1,5-benzothiazepine derivatives: promising new free-radical scavengers, and esterase, urease, and alpha-glucosidase inhibitors
Jiang_2005_Chem.Biodivers_2_557 Design, synthesis, and biological evaluation of new territrem B analogues
Liu_2005_Plant.Biotechnol.J_3_487 The production of synthetic chemodisruptive peptides in planta disrupts the establishment of cyst nematodes
Asano_2005_Biosci.Biotechnol.Biochem_69_2349 Screening for new hydroxynitrilases from plants
Baksh_2005_Langmuir_21_10693 Neuronal activation by GPI-linked neuroligin-1 displayed in synthetic lipid bilayer membranes
Boucard_2005_Neuron_48_229 A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins
Joshi_2005_Biochemistry_44_4100 Effect of modification of the length and flexibility of the acyl carrier protein-thioesterase interdomain linker on functionality of the animal fatty acid synthase
Khosravani_2005_FEBS.Lett_579_6587 The Arg473Cys-neuroligin-1 mutation modulates NMDA mediated synaptic transmission and receptor distribution in hippocampal neurons
Levinson_2005_Neuron_48_171 Building excitatory and inhibitory synapses: balancing neuroligin partnerships
Menendez_2005_Ann.Oncol_16_1253 Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2\/neu (erbB-2) oncogene
Pautot_2005_Nat.Chem.Biol_1_283 Neuronal synapse interaction reconstituted between live cells and supported lipid bilayers
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Shivdasani_2005_Curr.Protoc.Immunol_Chapter 22_Unit 22F 6 Culture, expansion, and differentiation of murine megakaryocytes
Vatsa_2005_Bioinorg.Chem.Appl__151 Synthesis, spectroscopic and toxicity studies of titanocene chelates of isatin-3-thiosemicarbazones
Haffner_2005_Bioorg.Med.Chem.Lett_15_5257 2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV
Munjam_2005_Hindustan.Antibiot.Bull_47-48_32 Production of lipases by four anoxygenic purple non-sulphur phototrophic bacteria
Song_2005_Mol.Pharm_2_157 Amino acid ester prodrugs of the anticancer agent gemcitabine: synthesis, bioconversion, metabolic bioevasion, and hPEPT1-mediated transport
Halamek_2005_Talanta_65_337 Piezoelectric affinity sensors for cocaine and cholinesterase inhibitors
Solna_2005_Talanta_65_349 Multienzyme electrochemical array sensor for determination of phenols and pesticides
Zhang_2005_Talanta_67_560 Increased paraoxon detection by acetylcholinesterase inactivation with ionic liquid additives
Hishinuma_2005_Rinsho.Byori_53_935 [Thyroglobulin gene abnormalities]
Hishinuma_2005_Thyroid_15_1079 High incidence of thyroid cancer in long-standing goiters with thyroglobulin mutations
Mendive_2005_Mol.Diagn_9_143 Nonsense-associated alternative splicing of the human thyroglobulin gene
Vono-Toniolo_2005_Thyroid_15_1021 Naturally occurring mutations in the thyroglobulin gene
Kuca_2005_Toxicol.Mech.Methods_15_247 Evaluation of newly synthesized reactivators of the brain cholinesterase inhibited by sarin nerve agent
Visalli_2005_Toxicol.Mech.Methods_15_383 Plasma butyrylcholinesterase activity protects against cocaine hepatotoxicity in female mice
Dong_2005_Mol.Cell.Proteomics_4_993 Modulation of differentiation-related gene 1 expression by cell cycle blocker mimosine, revealed by proteomic analysis
Gallwitz_2005_Rev.Diabet.Stud_2_61 New therapeutic strategies for the treatment of type 2 diabetes mellitus based on incretins
Gareri_2005_Clin.Drug.Investig_25_215 Melaena following Use of the Cholinesterase Inhibitor Rivastigmine
Grunewald_2005_Chem.Biol_12_873 Fluorescence resonance energy transfer as a probe of peptide cyclization catalyzed by nonribosomal thioesterase domains
Otsuki_2005_DNA.Res_12_117 Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries
Phillis_2005_Crit.Rev.Neurobiol_17_161 Acetylcholine release from the central nervous system: a 50-year retrospective
Safi_2005_Arch.Environ.Occup.Health_60_235 Hematological biomarkers in farm workers exposed to organophosphorus pesticides in the Gaza Strip
Scherl_2005_J.Microbiol.Methods_60_247 Correlation of proteomic and transcriptomic profiles of Staphylococcus aureus during the post-exponential phase of growth
Stark_2005_Cell_123_1133 Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution
Hackett_2005_Hum.Gene.Ther_16_1484 Safety of direct administration of AAV2(CU)hCLN2, a candidate treatment for the central nervous system manifestations of late infantile neuronal ceroid lipofuscinosis, to the brain of rats and nonhuman primates
Kethidi_2005_J.Insect.Physiol_51_393 Developmental and hormonal regulation of juvenile hormone esterase gene in Drosophila melanogaster
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Pruneta-Deloche_2005_J.Clin.Endocrinol.Metab_90_3995 Combination of circulating antilipoprotein lipase (Anti-LPL) antibody and heterozygous S172 fsX179 mutation of LPL gene leading to chronic hyperchylomicronemia
Arand_2005_Methods.Enzymol_400_569 Epoxide hydrolases: structure, function, mechanism, and assay
Hahn_2005_Biochim.Biophys.Acta_1731_125 Structure and expression of the zebrafish mest gene, an ortholog of mammalian imprinted gene PEG1\/MEST
Hsieh_2005_FEMS.Microbiol.Lett_243_339 Omp52 is a growth-phase-regulated outer membrane protein of Leptospira santarosai serovar Shermani
Imamura_2005_J.Biol.Chem_280_20171 Dynamic CpG and non-CpG methylation of the Peg1\/Mest gene in the mouse oocyte and preimplantation embryo
Kim_2005_Clin.Genet_67_267 Detection of maternal uniparental disomy at the two imprinted genes on chromosome 7, GRB10 and PEG1\/MEST, in a Silver-Russell syndrome patient using methylation-specific PCR assays
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Suzuki_2005_Mech.Dev_122_213 Genomic imprinting of IGF2, p57(KIP2) and PEG1\/MEST in a marsupial, the tammar wallaby
Sviderskii_2005_Dokl.Biochem.Biophys_401_142 Study of biochemical mechanism of action and toxic properties of a zinc-containing derivative of chlorophyll
Takahashi_2005_Am.J.Physiol.Endocrinol.Metab_288_E117 Mest\/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size
Zhu_2005_Microbiology_151_2363 Functions of the siderophore esterases IroD and IroE in iron-salmochelin utilization
Juhasz_2005_J.Mol.Biol_346_907 Unclosed beta-propellers display stable structures: implications for substrate access to the active site of prolyl oligopeptidase
Morton_2005_Cancer.Chemother.Pharmacol_56_629 Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice
Park_2005_Chem.Biol_12_45 Focusing mutations into the P. fluorescens esterase binding site increases enantioselectivity more effectively than distant mutations
Stinear_2005_Microbiology_151_683 Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans
Wierdl_2005_Curr.Hematol.Rep_4_294 Update on gene therapy approaches for cancer
Yoon_2005_Curr.Med.Chem.Anticancer.Agents_5_107 Development of prodrugs for enzyme-mediated, tumor-selective therapy
Miled_2005_Anal.Biochem_338_171 Discrimination between closed and open forms of lipases using electrophoretic techniques
Kim_2005_J.Med.Chem_48_3621 Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility
Maeda_2005_Angew.Chem.Int.Ed.Engl_44_2922 2,4-Dinitrobenzenesulfonyl fluoresceins as fluorescent alternatives to Ellman's reagent in thiol-quantification enzyme assays
Murdan_2005_Expert.Opin.Drug.Deliv_2_489 Organogels in drug delivery
Steiner_2005_Anal.Chem_77_4792 Detection of a chemical warfare agent simulant in various aerosol matrixes by ion mobility time-of-flight mass spectrometry
Wiesner_2005_Mil.Med.Sci.Lett_74_165 Computer Modeling and Simulation - New Technologies in Development of Means against Combat Chemical Substances
Karvaly_2005_J.Chromatogr.Sci_43_319 Quantitative analysis of the sulfur mustard hydrolysis product thiodiglycol (2,2'-sulfobisethanol) in in vivo microdialysates using gas chromatography coupled with pulsed flame photometric detection
Okumura_2005_Toxicol.Appl.Pharmacol_207_471 The Tokyo subway sarin attack--lessons learned
Vale_2005_Przegl.Lek_62_528 What lessons can we learn from the Japanese sarin attacks?
Haitina_2005_Ann.N.Y.Acad.Sci_1040_337 Pharmacological characterization of melanocortin receptors in fish suggests an important role for ACTH
Schioth_2005_Ann.N.Y.Acad.Sci_1040_460 Unusual genomic structure: melanocortin receptors in Fugu
Glauner_2005_Water.Res_39_4494 Swimming pool water--fractionation and genotoxicological characterization of organic constituents
Peichl_2005_Anat.Rec.A.Discov.Mol.Cell.Evol.Biol_287_1001 Diversity of mammalian photoreceptor properties: adaptations to habitat and lifestyle?
Topakas_2005_J.Biotechnol_115_355 Comparison of mesophilic and thermophilic feruloyl esterases: characterization of their substrate specificity for methyl phenylalkanoates
Ghanem_2005_Toxicol.Appl.Pharmacol_207_459 Detoxification of organophosphate nerve agents by bacterial phosphotriesterase
Nishimune_2005_J.Neurosci.Res_80_593 Neural adhesion molecules L1 and CHL1 are survival factors for motoneurons
Herholz_2005_Neuroreport_16_1431 Cerebral acetylcholine esterase activity in mild cognitive impairment
Pavlov_2005_Nano.Lett_5_649 Inhibition of the acetycholine esterase-stimulated growth of Au nanoparticles: nanotechnology-based sensing of nerve gases
Umezawa_2005_Biopolymers_79_248 CH\/pi hydrogen bonds as evidenced in the substrate specificity of acetylcholine esterase
Ambriz-Rivas_2005_Pflugers.Arch_450_255 K+-dependent stability and ion conduction of Shab K+ channels: a comparison with Shaker channels
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Leflemme_2005_J.Enzyme.Inhib.Med.Chem_20_551 Synthesis and preliminary in vivo evaluation of new 2-Aryl-6-methyl-1,2-dihydro-1H-pyridin-4-ones and 2-Aryl-6-methylpiperidin-4-ols, as potential anti-amnesiant agents
Omran_2005_Eur.J.Med.Chem_40_1222 Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil
Clark_2005_Nat.Neurosci_8_137 The site of action potential initiation in cerebellar Purkinje neurons
London_2005_Annu.Rev.Neurosci_28_503 Dendritic computation
Johnson_2005_J.Cogn.Neurosci_17_1897 The cerebral response during subjective choice with and without self-reference
Brand_2005_Neurochem.Res_30_1257 Translocation of ethanolamine phosphoglyceride is required for initiation of apoptotic death in OLN-93 oligodendroglial cells
Goldberg_2005_J.Neurosci_25_10230 Control of spontaneous firing patterns by the selective coupling of calcium currents to calcium-activated potassium currents in striatal cholinergic interneurons
Yavin_2005_Org.Biomol.Chem_3_2685 Synthesis and biological evaluation of lipophilic iron chelators as protective agents from oxidative stress
Bevilaqua_2005_Appl.Biochem.Biotechnol_121-124_117 Hydrolysis of new phthalimide-derived esters catalyzed by immobilized lipase
de Oliveira_2005_Appl.Biochem.Biotechnol_121-124_231 Kinetics of enzyme-catalyzed alcoholysis of soybean oil in n-hexane
Ronne_2005_J.Agric.Food.Chem_53_5617 Enzymatic interesterification of butterfat with rapeseed oil in a continuous packed bed reactor
Aldrich_2005_J.Am.Chem.Soc_127_8910 Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide
Venkatraman_2005_J.Org.Chem_70_7267 Formal total synthesis of the polyketide macrolactone narbonolide
Duxbury_2005_J.Am.Chem.Soc_127_2384 Can block copolymers be synthesized by a single-step chemoenzymatic route in supercritical carbon dioxide?
Kaihara_2005_Macromol.Biosci_5_644 Enzymatic transformation of bacterial polyhydroxyalkanoates into repolymerizable oligomers directed towards chemical recycling
Miao_2005_Biomacromolecules_6_3449 Synthesis, characterization, and degradation behavior of amphiphilic poly-alpha,beta-[N-(2-hydroxyethyl)-L-aspartamide]-g-poly(epsilon-caprolactone)
Tay_2005_J.Endod_31_737 Susceptibility of a polycaprolactone-based root canal filling material to degradation. II. Gravimetric evaluation of enzymatic hydrolysis
Ikeda_2005_J.Nutr_135_155 Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats
Fickers_2005_FEMS.Yeast.Res_5_527 Hydrophobic substrate utilisation by the yeast Yarrowia lipolytica, and its potential applications
Hiraoka_2005_J.Lipid.Res_46_2441 Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues
Choi_2005_Arch.Insect.Biochem.Physiol_59_53 Pheromone biosynthetic pathways in the moths Heliothis subflexa and Heliothis virescens
Fucinos_2005_J.Biotechnol_117_233 Identification of extracellular lipases\/esterases produced by Thermus thermophilus HB27: partial purification and preliminary biochemical characterisation
Oei_2005_Circulation_111_570 Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam Study
Leemhuis_2005_Curr.Opin.Struct.Biol_15_472 New genotype-phenotype linkages for directed evolution of functional proteins
Purcell_2005_J.Org.Chem_70_8437 The thermodynamics of phosphate versus phosphorothioate ester hydrolysis
Rademakers_2005_Am.J.Hum.Genet_77_643 Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample
Ali_2005_Pestic.Biochem.Physiol_83_58 Selectivity, acetylcholinesterase inhibition kinetics, and quantitative structure-activity relationships of a series of N-(2-oxido-1,3,2-benzodioxa-phosphol-2-yl) amino acid ethyl or diethyl esters
Kresge_2005_J.Biol.Chem_280_152 A Theory for the Molecular Basis of Bioelectricity: the Work of David Nachmansohn
Khanna_2005_Biotechnol.Prog_21_830 A simple structured mathematical model for biopolymer (PHB) production
Zheng_2005_Crit.Rev.Biotechnol_25_243 A review of plastic waste biodegradation
Dong_2005_J.Mol.Biol_353_655 Crystal structure of methyl parathion hydrolase from Pseudomonas sp. WBC-3
Khersonsky_2005_Biochemistry_44_6371 Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase
Dinnes_2005_Biomaterials_26_3881 Phospholipase A2 pathway association with macrophage-mediated polycarbonate-urethane biodegradation
Santerre_2005_Biomaterials_26_7457 Understanding the biodegradation of polyurethanes: from classical implants to tissue engineering materials
Koschorreck_2005_BMC.Genomics_6_49 How to find soluble proteins: a comprehensive analysis of alpha\/beta hydrolases for recombinant expression in E. coli
O'Leary_2005_Appl.Environ.Microbiol_71_4380 Genetic characterization of accumulation of polyhydroxyalkanoate from styrene in Pseudomonas putida CA-3
Yu_2005_Exp.Neurol_192_215 High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670\/671 mutation: a possible association with neuritic plaques
Mellou_2005_J.Biotechnol_116_295 Biocatalytic preparation of acylated derivatives of flavonoid glycosides enhances their antioxidant and antimicrobial activity
Salis_2005_J.Biotechnol_119_291 Biodiesel production from triolein and short chain alcohols through biocatalysis
Chica_2005_Curr.Opin.Biotechnol_16_378 Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design
Gunther_2005_Appl.Environ.Microbiol_71_2288 Production of rhamnolipids by Pseudomonas chlororaphis, a nonpathogenic bacterium
Lundy_2005_Toxicology_208_399 The pharmacokinetics and pharmacodynamics of two HI-6 salts in swine and efficacy in the treatment of GF and soman poisoning
Perrier_2005_Biochimie_87_673 Catabolism of intracellular N-terminal acetylated proteins: involvement of acylpeptide hydrolase and acylase
McDowell_2005_Mol.Plant.Microbe.Interact_18_1226 Genetic analysis of developmentally regulated resistance to downy mildew (Hyaloperonospora parasitica) in Arabidopsis thaliana
Pegadaraju_2005_Plant.Physiol_139_1927 Premature leaf senescence modulated by the Arabidopsis PHYTOALEXIN DEFICIENT4 gene is associated with defense against the phloem-feeding green peach aphid
Xiao_2005_Plant.J_42_95 The atypical resistance gene, RPW8, recruits components of basal defence for powdery mildew resistance in Arabidopsis
Fornage_2005_Hum.Mol.Genet_14_2829 The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke
Kosaka_2005_Clin.Chim.Acta_359_156 Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay
Togawa_2005_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_819_67 Measurement of homocysteine thiolactone hydrolase activity using high-performance liquid chromatography with fluorescence detection and polymorphisms of paraoxonase in normal human serum
Sakashita_2005_Bioorg.Med.Chem.Lett_15_2441 1-((S)-gamma-substituted prolyl)-(S)-2-cyanopyrrolidine as a novel series of highly potent DPP-IV inhibitors