2019

Zhang_2019_Biomolecules_9_439 Integrated Approaches to Reveal Genes Crucial for Tannin Degradation in Aureobasidium melanogenum T9
Jin_2019_Mar.Drugs_17_ Enantioselective Hydrolysis of Styrene Oxide and Benzyl Glycidyl Ether by a Variant of Epoxide Hydrolase from Agromyces mediolanus
Calchera_2019_Molecules_24_203 Biosynthetic Gene Content of the 'Perfume Lichens' Evernia prunastri and Pseudevernia furfuracea
Duan_2019_Food.Chem_297_124925 Biochemical characterization of a novel lipase from Malbranchea cinnamomea suitable for production of lipolyzed milkfat flavor and biodegradation of phthalate esters
Thomas_2019_Mol.Catal_473_110402 LipG9-mediated enzymatic kinetic resolution of racemates: Expanding the substrate-scope for a metagenomic lipase
Wang_2019_Int.J.Biol.Macromol_136_1042 Characterization, immobilization, and mutagenesis of a novel cold-active acetylesterase (EaAcE) from Exiguobacterium antarcticum B7
Wang_2019_Biocatal.Biotransformation_37_190 Characterization of one novel microbial esterase WDEst9 and its use to make l-methyl lactate
Ay Sal_2019_Mol.Biol.Rep_46_4385 Biochemical characterization of a novel thermostable feruloyl esterase from Geobacillus thermoglucosidasius DSM 2542(T)
Liebschner_2019_Acta.Crystallogr.D.Struct.Biol_75_861 Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Felix_2019_Sci.Rep_9_13144 A multi-omics analysis of the grapevine pathogen Lasiodiplodia theobromae reveals that temperature affects the expression of virulence- and pathogenicity-related genes
Estrela_2019_mBio_10_e02587 Functional Multigenomic Screening of Human-Associated Bacteria for NF-B-Inducing Bioactive Effectors
Wang_2019_Org.Lett_21_8756 Investigating the Function of Cryptic Cytochalasan Cytochrome P450 Monooxygenases Using Combinatorial Biosynthesis
Wang_2019_Org.Lett_21_4163 Targeted Gene Inactivations Expose Silent Cytochalasans in Magnaporthe grisea NI980
Ahmad_2019_Polym.Degrad.Stab_164_109 Gene structure and comparative study of two different plastic-degrading esterases fromRoseateles depolymeransstrain TB-87
Zhao_2019_J.Agric.Food.Chem_67_6940 Bioaugmentation of Exogenous Strain Rhodococcus sp. 2G Can Efficiently Mitigate Di(2-ethylhexyl) Phthalate Contamination to Vegetable Cultivation
Zhang_2019_AMB.Express_9_13 Synergistic effect of acetyl xylan esterase from Talaromyces leycettanus JCM12802 and xylanase from Neocallimastix patriciarum achieved by introducing carbohydrate-binding module-1
Kryukova_2019_Biomolecules_9_880 Thermal Inactivation of a Cold-Active Esterase PMGL3 Isolated from the Permafrost Metagenomic Library
Zhang_2019_Proc.Natl.Acad.Sci.U.S.A_116_13305 Compartmentalized biosynthesis of mycophenolic acid
Yoshida_2019_Biosci.Biotechnol.Biochem_83_1974 Production of recombinant extracellular cholesterol esterase using consistently active promoters in Burkholderia stabilis
Park_2019_Front.Microbiol_10_3069 Characterization of a Novel Moderately Thermophilic Solvent-Tolerant Esterase Isolated From a Compost Metagenome Library
Elahi_2019_Sci.Rep_9_17532 Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum
Zhang_2019_Int.J.Mol.Med_44_2047 FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis
Almeida_2019_Front.Microbiol_10_2187 In silico Screening and Heterologous Expression of a Polyethylene Terephthalate Hydrolase (PETase)-Like Enzyme (SM14est) With Polycaprolactone (PCL)-Degrading Activity, From the Marine Sponge-Derived Strain Streptomyces sp. SM14
Garcia-Orozco_2019_Biomolecules_9_ Biochemical Characterization of a Novel alpha\/beta-Hydrolase\/FSH from the White Shrimp Litopenaeus vannamei
Holck_2019_J.Biol.Chem_294_17339 A carbohydrate-binding family 48 module enables feruloyl esterase action on polymeric arabinoxylan
Holck_2019_Enzyme.Microb.Technol_129_109353 Novel xylanolytic triple domain enzyme targeted at feruloylated arabinoxylan degradation
Hettiarachchi_2019_Microb.Cell.Fact_18_122 Characterization of an acetyl xylan esterase from the marine bacterium Ochrovirga pacifica and its synergism with xylanase on beechwood xylan
Wei_2019_iScience_19_796 Molecular Basis of BioJ, a Unique Gatekeeper in Bacterial Biotin Synthesis
Almeida_2019_Int.J.Biol.Macromol_137_442 Biochemical characterization and application of a new lipase and its cognate foldase obtained from a metagenomic library derived from fat-contaminated soil
Shang_2019_Biochem.Biophys.Res.Commun_519_274 Structural and functional analyses of the lipase CinB from Enterobacter asburiae
Lee_2019_Proc.Natl.Acad.Sci.U.S.A_116_18031 Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity
Zhou_2019_Chem.Sci_10_6341 Molecular mechanism of polyketide shortening inanthraquinone biosynthesis of Photorhabdus luminescens
Tang_2019_J.Am.Chem.Soc_141_8198 Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi
Ding_2019_Biotechnol.Lett_41_1059 Identification and characterization of an acetyl esterase from Paenibacillus sp. XW-6-66 and its novel function in 7-aminocephalosporanic acid deacetylation
Kreitler_2019_Nat.Commun_10_3432 The structural basis of N-acyl-alpha-amino-beta-lactone formation catalyzed by a nonribosomal peptide synthetase
Meng_2019_Appl.Biochem.Biotechnol_189_1304 Cloning, Characterization, and Functional Expression of a Thermostable Type B Feruloyl Esterase from Thermophilic Thielavia Terrestris
Guo_2019_Front.Cell.Infect.Microbiol_9_199 Molecular and Biochemical Characterization of a Type II Thioesterase From the Zoonotic Protozoan Parasite Cryptosporidium parvum
Cao_2019_ACS.Catal_9_1739 Structural Insights into the Dual-Substrate Recognition and Catalytic Mechanisms of a Bifunctional Acetyl Ester-Xyloside Hydrolase from Caldicellulosiruptor lactoaceticus
Martim_2019_Appl.Biochem.Biotechnol_189_834 Two Novel Acetylesterases from Pantoea dispersa: Recombinant Expression, Purification, and Characterization
Wu_2019_Biotechnol.Lett_41_995 Molecular cloning, expression and characterization of a novel feruloyl esterase from a soil metagenomic library with phthalate-degrading activity
Kishimoto_2019_Breed.Sci_69_117 Comparison of petunia and calibrachoa in carotenoid pigmentation of corollas
Lu_2019_Appl.Microbiol.Biotechnol_103_3421 Biochemical profiles of two thermostable and organic solvent-tolerant esterases derived from a compost metagenome
Castillo Villamizar_2019_MBio_10_ Functional Metagenomics Reveals an Overlooked Diversity and Novel Features of Soil-Derived Bacterial Phosphatases and Phytases
Hu_2019_J.Am.Chem.Soc_141_8068 Fungal Dirigent Protein Controls the Stereoselectivity of Multicopper Oxidase-Catalyzed Phenol Coupling in Viriditoxin Biosynthesis
Chaloupkova_2019_ACS.Catal_9_48103 Light-Emitting Dehalogenases: Reconstruction of Multifunctional Biocatalysts
Sameshima-Yamashita_2019_Biosci.Biotechnol.Biochem__1 Construction of a Pseudozyma antarctica strain without foreign DNA sequences (self-cloning strain) for high yield production of a biodegradable plastic-degrading enzyme
Chen_2019_Biomed.Res.Int_2019_4862647 Ester-Producing Mechanism of Ethanol O-acyltransferase EHT1 Gene in Pichia pastoris from Shanxi Aged Vinegar
Li_2019_Mol.Catal_476_110517 Improving the activity and enantioselectivity of PvEH1, a Phaseolus vulgaris epoxide hydrolase, for o-methylphenyl glycidyl ether by multiple site-directed mutagenesis on the basis of rational design
Zong_2019_Microb.Cell.Fact_18_202 Substantially improving the enantioconvergence of PvEH1, a Phaseolus vulgaris epoxide hydrolase, towards m-chlorostyrene oxide by laboratory evolution
Li_2019_Int.J.Biol.Macromol_121_326 Multiple site-directed mutagenesis of a Phaseolus vulgaris epoxide hydrolase to improve its catalytic performance towards p-chlorostyrene oxide based on the computer-aided re-design
Bonzom_2019_AMB.Express_9_126 Glycosylation influences activity, stability and immobilization of the feruloyl esterase 1a from Myceliophthora thermophila
Wang_2019_3.Biotech_9_33 High-level expression of Thermomyces dupontii thermo-alkaline lipase in Pichia pastoris under the control of different promoters
Cerullo_2019_N.Biotechnol_51_14 Directed evolution of the type C feruloyl esterase from Fusarium oxysporum FoFaeC and molecular docking analysis of its improved variants
Zhao_2019_Arch.Insect.Biochem.Physiol__e21554 Molecular and functional properties of two Spodoptera exigua acetylcholinesterase genes
Liu_2019_J.Agric.Food.Chem_67_836 Directed Evolution of Sulfonylurea Esterase and Characterization of a Variant with Improved Activity
Tang_2019_Int.J.Mol.Sci_20_ A Thermostable Monoacylglycerol Lipase from Marine Geobacillus sp. 12AMOR1: Biochemical Characterization and Mutagenesis Study
Palm_2019_Nat.Commun_10_1717 Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to a substrate
Son_2019_ACS.Catal_9_3519 Rational Protein Engineering of Thermo-Stable PETase from Ideonella sakaiensis for Highly Efficient PET Degradation
Seo_2019_Biochem.Biophys.Res.Commun_508_250 Production of extracellular PETase from Ideonella sakaiensis using sec-dependent signal peptides in E. coli
Liu_2019_Biochem.Biophys.Res.Commun_508_289 Structural and functional characterization of polyethylene terephthalate hydrolase from Ideonella sakaiensis
Hiraga_2019_EMBO.Rep_20_e49365 Biodegradation of waste PET: A sustainable solution for dealing with plastic pollution
de Oliveira_2019_Int.J.Biol.Macromol_129_653 The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors
de Oliveira_2019_Mol.Biol.Rep_46_371 Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei
Lees_2019_Angew.Chem.Int.Ed.Engl_58_2305 An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate\/Spirotetramate Biosynthesis
Wang_2019_Molecules_24_ Insight into the Modification of Phosphatidylcholine with n-3 Polyunsaturated Fatty Acids-Rich Ethyl Esters by Immobilized MAS1 Lipase
Alonso_2020_Nat.Catal_3_319 Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Kjolbye_2019_J.Chem.Inf.Model_59_1977 Molecular Modeling Investigation of the Interaction between Humicola insolens Cutinase and SDS Surfactant Suggests a Mechanism for Enzyme Inactivation
Zhang_2019_Biochemistry_58_3943 Structural Basis by Which the N-Terminal Polypeptide Segment of Rhizopus chinensis Lipase Regulates Its Substrate Binding Affinity
Dachuri_2019_Extremophiles_23_649 Distinct roles of an ionic interaction holding an alpha-helix with catalytic Asp and a beta-strand with catalytic His in a hyperthermophilic esterase EstE1 and a mesophilic esterase rPPE
Kitadokoro_2019_FEBS.J_286_2087 Structural insights into the unique polylactate-degrading mechanism of Thermobifida alba cutinase
Huguenin-Dezot_2019_Nature_565_112 Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid
Chrast_2019_Microorganisms_7_ Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17
Martini_2019_N.Biotechnol_53_65 Structure solution and analyses of the first true lipase obtained from metagenomics indicate potential for increased thermostability
Leclere_2019_Nat.Ecol.Evol_3_801 The genome of the jellyfish Clytia hemisphaerica and the evolution of the cnidarian life-cycle
d'Andrea_2019_Cell.Chem.Biol_26_878 Late-Stage Conversion of Diphenylphosphonate to Fluorophosphonate Probes for the Investigation of Serine Hydrolases
Patel_2019_Nat.Commun_10_3868 Structure of a bound peptide phosphonate reveals the mechanism of nocardicin bifunctional thioesterase epimerase-hydrolase half-reactions
Paya-Tormo_2019_Front.Bioeng.Biotechnol_7_71 Improvement of the Activity of a Fungal Versatile-Lipase Toward Triglycerides: An in silico Mechanistic Description
Jangir_2019_Bioorg.Chem_84_32 Immobilized Baliospermum montanum hydroxynitrile lyase catalyzed synthesis of chiral cyanohydrins
Elsayed_2019_Mol.Biol.Rep_46_3357 New insight into poly (3-hydroxybutyrate) production by Azomonas macrocytogenes isolate KC685000: large scale production, kinetic modeling, recovery and characterization
Marcombe_2019_PLoS.Negl.Trop.Dis_13_e0007852 Distribution of insecticide resistance and mechanisms involved in the arbovirus vector Aedes aegypti in Laos and implication for vector control
Xu_2019_Anim.Genet_50_287 Genome-wide association studies reveal genetic loci associated with plasma cholinesterase activity in ducks
Aulakh_2019_Plant.Physiol_180_1962 The Plastid Lipase PLIP1 Is Critical for Seed Viability in diacylglycerol acyltransferase1 Mutant Seed
Lapin_2019_Plant.Cell_31_2430 A Coevolved EDS1-SAG101-NRG1 Module Mediates Cell Death Signaling by TIR-Domain Immune Receptors
Seto_2019_Nat.Commun_10_191 Strigolactone perception and deactivation by a hydrolase receptor DWARF14
Hu_2019_J.Chem.Inf.Model_59_1554 MD Simulation Investigation on the Binding Process of Smoke-Derived Germination Stimulants to Its Receptor
Miao_2019_J.Biol.Chem_294_6214 Thermodynamic insights into an interaction between ACYL-CoA-BINDING PROTEIN2 and LYSOPHOSPHOLIPASE2 in Arabidopsis
Rao_2019_Chembiochem_20_371 Production of (S)-beta-Nitro Alcohols by Enantioselective C-C Bond Cleavage with an R-Selective Hydroxynitrile Lyase
Arnaiz_2019_Front.plant.Sci_10_930 Plant Defenses Against Pests Driven by a Bidirectional Promoter
Fukui_2019_Bioorg.Med.Chem.Lett_29_2487 Synthetic agonist of HTL\/KAI2 shows potent stimulating activity for Arabidopsis seed germination
Huang_2019_FEBS.J_286_2366 Structure and characterization of Aspergillus fumigatus lipase B with a unique, oversized regulatory subdomain
Zheng_2019_Protein.Expr.Purif_155_1 High-level expression and characterization of a stereoselective lipase from Aspergillus oryzae in Pichia pastoris
Yang_2019_Biosci.Biotechnol.Biochem__1 Characterization of a novel thermostable carboxylesterase from thermoalkaliphilic bacterium Bacillus thermocloaceae
Tian_2019_Toxins.(Basel)_11_ CesH Represses Cereulide Synthesis as an Alpha\/Beta Fold Hydrolase in Bacillus cereus
Xia_2019_Protein.Pept.Lett_26_702 Thermostability of Lipase A and Dynamic Communication Based on Residue Interaction Network
Godoy_2019_Int.J.Mol.Sci_20_ Disulfide Engineered Lipase to Enhance the Catalytic Activity: A Structure-Based Approach on BTL2
Temeyer_2019_J.Med.Entomol_56_1318 Baculoviral Expression of Presumptive OP-Resistance Mutations in BmAChE1 of Rhipicephalus (Boophilus) microplus (Ixodida: Ixodidae) and Biochemical Resistance to OP Inhibition
Shi_2019_Genes.(Basel)_10_ Determination of Genetic Effects of LIPK and LIPJ Genes on Milk Fatty Acids in Dairy Cattle
Wang_2019_Gene_690_38 Molecular characterization of ABHD5 gene promoter in intramuscular preadipocytes of Qinchuan cattle: Roles of Evi1 and C\/EBPalpha
Pudnikova_2019_Crystals_9_375 Crystallization and Crystallographic Analysis of a Bradyrhizobium Elkanii USDA94 Haloalkane Dehalogenase Variant with an Eliminated Halide-Binding Site
Borowiecki_2019_Bioorg.Chem_93_102754 A facile lipase-catalyzed KR approach toward enantiomerically enriched homopropargyl alcohols
Putra_2019_J.Microbiol.Biotechnol_29_944 Isolation, Cloning and Co-Expression of Lipase and Foldase Genes of Burkholderia territorii GP3 from Mount Papandayan Soil
Kozlova_2019_Genetics_212_231 Cross Talk with the GAR-3 Receptor Contributes to Feeding Defects in Caenorhabditis elegans eat-2 Mutants
Ramachandran_2019_Dev.Cell_48_685 Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity
Zhao_2019_Sci.Total.Environ_700_134492 Graphene oxide disrupts the protein-protein interaction between Neuroligin\/NLG-1 and DLG-1 or MAGI-1 in nematode Caenorhabditis elegans
Kumar_2019_Synth.Commun_49_1659 Biocatalyst CAL-B catalyzed synthesis of modified nucleosides: An overview
Xu_2019_J.Am.Chem.Soc_141_7934 Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters
Cen_2019_Nat.Commun_10_3198 Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution
Parikh_2019_Biotechnol.Lett_41_1163 Kinetics and thermodynamics of lipase catalysed synthesis of propyl caprate
Han_2019_Bioprocess.Biosyst.Eng_42_1739 Rational enhancement of enzyme-catalyzed enantioselective reaction by construction of recombinant enzymes based on additive strategy
Ortiz_2019_Catal.Sci.Technol_9_2380 Novozym 435: the 'perfect' lipase immobilized biocatalyst?
Li_2019_Int.J.Biol.Macromol_137_215 Effect of organic solvent on enzymatic degradation of cyclic PBS-based polymers by lipase N435
Quaglia_2019_PLoS.One_14_e0210100 Holistic engineering of Cal-A lipase chain-length selectivity identifies triglyceride binding hot-spot
Lofgren_2019_Chembiochem_20_1438 Transesterification of a Tertiary Alcohol by Engineered Candida antarctica Lipase A
Nasri_2019_Molecules_24_ Inhibition of CpLIP2 Lipase Hydrolytic Activity by Four Flavonols (Galangin, Kaempferol, Quercetin, Myricetin) Compared to Orlistat and Their Binding Mechanisms Studied by Quenching of Fluorescence
Huang_2019_Sci.Rep_9_1379 Telencephalon transcriptome analysis of chronically stressed adult zebrafish
de Farias_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_215_1 Exposure to low concentration of fluoxetine affects development, behaviour and acetylcholinesterase activity of zebrafish embryos
Ragavendran_2019_Front.Microbiol_10_427 Larvicidal, Histopathological, Antibacterial Activity of Indigenous Fungus Penicillium sp. Against Aedes aegypti L and Culex quinquefasciatus (Say) (Diptera: Culicidae) and Its Acetylcholinesterase Inhibition and Toxicity Assessment of Zebrafish (Danio rerio)
Yadav_2019_J.Biol.Chem_294_89 Carboxypeptidase in prolyl oligopeptidase family: Unique enzyme activation and substrate-screening mechanisms
Vanderlinde_2019_J.Hered_110_118 An Improved Genome Assembly for Drosophila navojoa, the Basal Species in the mojavensis Cluster
Hehlert_2019_J.Lipid.Res_60_1365 The alpha\/beta-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila
Hopkins_2019_Insect.Biochem.Mol.Biol_106_10 The molecular basis for the neofunctionalization of the juvenile hormone esterase duplication in Drosophila
Alfaro-Chavez_2019_Protein.Eng.Des.Sel_32_13 Improving on nature's shortcomings: evolving a lipase for increased lipolytic activity, expression and thermostability
Bermudez-Garcia_2019_Appl.Microbiol.Biotechnol_103_3863 Regulation of the cutinases expressed by Aspergillus nidulans and evaluation of their role in cutin degradation
Curci_2019_Extremophiles_23_407 Identification of a novel esterase from the thermophilic bacterium Geobacillus thermodenitrificans NG80-2
Moharana_2019_Biochem.Biophys.Res.Commun_508_145 X-ray structure and characterization of a thermostable lipase from Geobacillus thermoleovorans
Ishak_2019_Int.J.Mol.Sci_20_E2561 Changes of Thermostability, Organic Solvent, and pH Stability in Geobacillus zalihae HT1 and Its Mutant by Calcium Ion
Wang_2019_Int.J.Biol.Macromol_132_1051 Exploring the influence of phospholipid monolayer conformation and environmental conditions on the interfacial binding of Gibberella Zeae lipase
Farrow_2019_J.Am.Chem.Soc_141_12979 Biosynthesis of an Anti-Addiction Agent from the Iboga Plant
Huang_2019_J.Agric.Food.Chem_67_8548 Biodegradation of Structurally Diverse Phthalate Esters by a Newly Identified Esterase with Catalytic Activity toward Di(2-ethylhexyl) Phthalate
Bai_2019_Pestic.Biochem.Physiol_157_69 Identification and biochemical characterization of carboxylesterase 001G associated with insecticide detoxification in Helicoverpa armigera
Francis_2019_Antimicrob.Agents.Chemother_63_e01964 A Population Pharmacokinetic Analysis Shows that Arylacetamide Deacetylase (AADAC) Gene Polymorphism and HIV Infection Affect the Exposure of Rifapentine
Parker_2019_Nature_567_187 An integrative systems genetic analysis of mammalian lipid metabolism
Baggelaar_2019_ACS.Chem.Biol_14_2295 ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction
Nielsen_2019_Sci.Rep_9_12866 Characterisation and localisation of the endocannabinoid system components in the adult human testis
Yu_2019_Int.J.Mol.Sci_20_ Retinoic Acid Induces Differentiation of Mouse F9 Embryonic Carcinoma Cell by Modulating the miR-485 Targeting of Abhd2
Jebessa_2019_Nat.Metab_1_1157 The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4
Yang_2019_Nat.Metab_1_560 Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes
Ou_2019_Nat.Commun_10_1078 ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield
Shang_2019_Cancer.Res_79_5513 Macrophage ABHD5 Suppresses NFkappaB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis
Zhou_2019_Cancer.Manag.Res_11_2139 Oncogenic role of ABHD5 in endometrial cancer
Grabner_2019_J.Lipid.Res_60_1020 Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans
Bottemanne_2019_FASEB.J__fj201802259R The alpha\/beta-hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids
Rahaman_2019_J.Immunol_202_1674 Cutting Edge: Dysregulated Endocannabinoid-Rheostat for Plasmacytoid Dendritic Cell Activation in a Systemic Lupus Endophenotype
van Esbroeck_2019_Front.Mol.Neurosci_12_286 Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells
Shields_2019_Sci.Rep_9_890 Biochemical and Proteomic Characterization of Recombinant Human alpha\/beta Hydrolase Domain 6
Cao_2019_Trends.Pharmacol.Sci_40_267 ABHD6: Its Place in Endocannabinoid Signaling and Beyond
Drehmer_2019_Biochem.Genet_57_35 Gene Expression of ABHD6, a Key Factor in the Endocannabinoid System, Can Be Modulated by Female Hormones in Human Immune Cells
Turcotte_2019_J.Leukoc.Biol_106_1337 Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways
Cao_2019_Nat.Chem.Biol_15_1232 ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5
He_2019_J.Cell.Physiol_234_12070 Long noncoding RNA ABHD11-AS1 promote cells proliferation and invasion of colorectal cancer via regulating the miR-1254-WNT11 pathway
Park_2019_Neurosci.Res_147_58 Non-coding RNA Neat1 and Abhd11os expressions are dysregulated in medium spiny neurons of Huntington disease model mice
Liu_2019_J.Cancer_10_3746 Circulating lncRNA ABHD11-AS1 serves as a biomarker for early pancreatic cancer diagnosis
Wen_2019_Cell.Prolif_52_e12569 STAT3-induced upregulation of lncRNA ABHD11-AS1 promotes tumour progression in papillary thyroid carcinoma by regulating miR-1301-3p\/STAT3 axis and PI3K\/AKT signalling pathway
Zeng_2019_Cancer.Med_8_7074 lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2
Zhuang_2019_Cell.Death.Dis_10_620 Long noncoding RNA ABHD11-AS1 functions as a competing endogenous RNA to regulate papillary thyroid cancer progression by miR-199a-5p\/SLC1A5 axis
Ogasawara_2019_J.Med.Chem_62_1643 Discovery and Optimization of Selective and in Vivo Active Inhibitors of the Lysophosphatidylserine Lipase alpha\/beta-Hydrolase Domain-Containing 12 (ABHD12)
Kelkar_2019_Nat.Chem.Biol_15_169 A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase
Stockli_2019_Mol.Metab_25_83 ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation
Zueva_2019_Neuropharmacol_155_131 New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease
Bester_2019_Protein.Sci_28_1106 The structural and biochemical impacts of monomerizing human acetylcholinesterase
Gerlits_2019_Chem.Biol.Interact_13ChEPon_ A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies
Gerlits_2019_J.Biol.Chem_294_10607 Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase
Hsu_2019_ACS.Med.Chem.Lett_10_761 Synthesis and Molecular Properties of Nerve Agent Reactivator HLo-7 Dimethanesulfonate
Kovarik_2019_Toxicol.Appl.Pharmacol_372_40 Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase
Dighe_2019_Commun.Chem_2_35 Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model.
Meden_2019_Chem.Commun.(Camb)_55_3765 Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease
Touvrey_2019_Toxicology_411_15 X-ray structures of human bile-salt activated lipase conjugated to nerve agents surrogates
Stage_2019_Basic.Clin.Pharmacol.Toxicol_125_54 The impact of human CES1 genetic variation on enzyme activity assessed by ritalinic acid\/methylphenidate ratios
Yan_2019_Molecules_24_ Catalytic Hydrolysis Mechanism of Cocaine by Human Carboxylesterase 1: An Orthoester Intermediate Slows Down the Reaction
Saiz-Rodriguez_2019_Clin.Ther_41_1199 Influence of CYP450 Enzymes, CES1, PON1, ABCB1, and P2RY12 Polymorphisms on Clopidogrel Response in Patients Subjected to a Percutaneous Neurointervention
Qian_2019_Drug.Metab.Dispos_47_465 In Vitro Inhibition of Carboxylesterase 1 by Major Cannabinoids and Selected Metabolites
Sychev_2019_Mol.Biol.Rep_46_2761 Genetic determinants of dabigatran safety (CES1 gene rs2244613 polymorphism) in the Russian population: multi-ethnic analysis
Goeppert_2019_Sci.Rep_9_4338 Prognostic Impact of Carboxylesterase 2 in Cholangiocarcinoma
Tian_2019_Anal.Chem_91_15840 Endoplasmic Reticulum Targeting Ratiometric Fluorescent Probe for Carboxylesterase 2 Detection in Drug-Induced Acute Liver Injury
Kailass_2019_Chem.Sci_10_8428 Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor
Yang_2019_Diabetes_68_1178 A Unique Role of Carboxylesterase 3 (Ces3) in beta-Adrenergic Signaling-Stimulated Thermogenesis
Mukherjee_2019_Appl.Physiol.Nutr.Metab_44_1089 Novel regulatory roles of carboxylesterase 3 in lipid metabolism and browning in 3T3-L1 white adipocytes
Li_2019_J.Med.Chem_62_2348 Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
Micieli_2019_Neurology_92_e2298 Teaching Video NeuroImages: Opsoclonus in anti-DPPX encephalitis
Sato_2019_Sci.Rep_9_18094 DPP8 is a novel therapeutic target for multiple myeloma
Gai_2019_Cell.Death.Dis_10_587 DPP8\/9 inhibitors are universal activators of functional NLRP1 alleles
de Vasconcelos_2019_Life.Sci.Alliance_2_ DPP8\/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages
Brunetti_2019_Virchows.Arch_474_177 Expression and clinical role of the dipeptidyl peptidases DPP8 and DPP9 in ovarian carcinoma
Griswold_2019_ACS.Chem.Biol_14_2424 DPP9's Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation
Gall_2019_Sci.Rep_9_7292 Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity
Belau_2019_Int.J.Cardiol_284_68 DPP10 is a new regulator of Nav1.5 channels in human heart
Abis_2019_Commun.Biol_2_188 15-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism
Hiesinger_2019_ACS.Med.Chem.Lett_10_899 Computer-Aided Selective Optimization of Side Activities of Talinolol
Sheila_2019_Neurobiol.Dis_124_1 Phenotypic and molecular features underlying neurodegeneration of motor neurons derived from spinal and bulbar muscular atrophy patients
Bracke_2019_Clin.Chim.Acta_495_154 The development and validation of a combined kinetic fluorometric activity assay for fibroblast activation protein alpha and prolyl oligopeptidase in plasma
Mayanskiy_2019_JIMD.Rep_48_75 A kinetic assay of total lipase activity for detecting lysosomal acid lipase deficiency (LAL-D) and the molecular characterization of 18 LAL-D patients from Russia
Kamoun_2019_Food.Funct_10_469 Identification of a new natural gastric lipase inhibitor from star anise
Yang_2019_Lipids.Health.Dis_18_10 LIPG SNPs, their haplotypes and gene-environment interactions on serum lipid levels
Meng_2019_Bioorg.Med.Chem.Lett__126673 Benzothiazole-based compounds as potent endothelial lipase inhibitors
Kim_2019_Bioorg.Med.Chem.Lett_29_1918 Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase
Arora_2019_Proc.Natl.Acad.Sci.U.S.A_116_10360 Structure of lipoprotein lipase in complex with GPIHBP1
Birrane_2019_Proc.Natl.Acad.Sci.U.S.A_116_1723 Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis
Oteng_2019_J.Lipid.Res_60_1741 Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice
Young_2019_Cell.Metab_30_51 GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism
Beigneux_2019_Proc.Natl.Acad.Sci.U.S.A_116_6319 Lipoprotein lipase is active as a monomer
Mohammed_2019_Oncol.Rep_41_973 Inhibition of cell proliferation and migration in nonsmall cell lung cancer cells through the suppression of LYPLA1
Wepy_2019_J.Lipid.Res_60_360 Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling
Norheim_2019_Cell.Metab_29_932 Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits
Dato_2019_Bioorg.Chem__103352 omega-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase
Chen_2019_J.Med.Chem_62_3336 Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton
Poli_2019_J.Enzyme.Inhib.Med.Chem_34_589 Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors
Hattori_2019_J.Med.Chem_62_2362 Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-((18)F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbo nyl)piperazin-1-yl]pyrrolidin-2-one ([(18)F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase
Yamazaki_2019_J.Atheroscler.Thromb_26_246 Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells
Yu_2019_Oncol.Lett_18_1337 SNHG20\/miR-140-5p\/NDRG3 axis contributes to 5-fluorouracil resistance in gastric cancer
Kim_2019_Int.J.Clin.Exp.Pathol_12_3886 NDRG3 protein expression is associated with aggressive biologic phenotype and unfavorable outcome in patients with invasive breast cancer
Shi_2019_BMB.Rep_52_451 High NDRG3 expression facilitates HCC metastasis by promoting nuclear translocation of beta-catenin
Ross_2019_Am.J.Med.Genet.B.Neuropsychiatr.Genet_180_471 Y chromosome gene copy number and lack of autism phenotype in a male with an isodicentric Y chromosome and absent NLGN4Y expression
Zhao_2019_J.Pineal.Res__e12630 Structural characterisation of melatonin as an inhibitor of the Wnt deacylase Notum
Li_2019_Biol.Res_52_10 Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways
Brommage_2019_Bone.Res_7_2 NOTUM inhibition increases endocortical bone formation and bone strength
Willis_2019_Beilstein.J.Org.Chem_15_2790 An improved, scalable synthesis of Notum inhibitor LP-922056 using 1-chloro-1,2-benziodoxol-3-one as a superior electrophilic chlorinating agent
Atkinson_2019_Bioorg.Med.Chem.Lett__126751 Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors
Pentinmikko_2019_Nature_571_398 Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium
Moverare-Skrtic_2019_FASEB.J__fj201900707R Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans
De Mauri_2019_J.Nephrol_32_283 Lipoprotein-associated phospholipase A2 predicts cardiovascular events in dialyzed patients
Zhang_2019_Eur.Rev.Med.Pharmacol.Sci_23_3960 The association between the D166E polymorphism of the lipoprotein associated phospholipase A2 and risk of myocardial infarction
Hu_2019_Biomed.Res.Int_2019_8642784 Lipoprotein-Associated Phospholipase A2 Activity and Mass as Independent Risk Factor of Stroke: A Meta-Analysis
Shayman_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_932 Lysosomal phospholipase A2
Lasher_2019_Am.J.Gastroenterol_114_974 Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis
Jin_2019_Aging.(Albany.NY)_11_9672 Glycogen synthase kinase-3beta suppresses the expression of protein phosphatase methylesterase-1 through beta-catenin
Koster_2019_Front.Synaptic.Neurosci_11_25 Depalmitoylation by Palmitoyl-Protein Thioesterase 1 in Neuronal Health and Degeneration
Tucker_2019_Hum.Mutat_40_886 TP63-truncating variants cause isolated premature ovarian insufficiency
de Wijn_2019_IUCrJ_6_454 A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography
Bohr_2019_Sci.Rep_9_16169 Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition
Soni_2019_Biotechnol.Biofuels_12_110 N-terminal domain replacement changes an archaeal monoacylglycerol lipase into a triacylglycerol lipase
Wang_2019_Biochem.Biophys.Res.Commun_520_538 Structural insight into the carboxylesterase BioH from Klebsiella pneumoniae
Zhang_2019_Int.J.Mol.Sci_20_ Whole Genome Sequencing and Analysis of Chlorimuron-Ethyl Degrading Bacteria Klebsiella pneumoniae 2N3
Ojennus_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_625 Structural characterization of a prolyl aminodipeptidase (PepX) from Lactobacillus helveticus
Correy_2019_Proc.Natl.Acad.Sci.U.S.A_116_21012 Overcoming insecticide resistance through computational inhibitor design
Leopold_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_500 Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation
Norris_2019_Mol.Autism_10_42 Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference
Hosie_2019_Autism.Res_12_1043 Gastrointestinal dysfunction in patients and mice expressing the autism-associated R451C mutation in neuroligin-3
Leishman_2019_Front.Mol.Neurosci_12_142 Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype
Lian_2019_J.Lipid.Res_60_880 Ces1d deficiency protects against high-sucrose diet-induced hepatic triacylglycerol accumulation
Maresch_2019_Hepatol.Commun_3_227 Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity
Pimienta_2019_Hepatol.Commun_3_177 Intestinal Lipolysis Mitigates Nonalcoholic Fatty Liver Disease: New Roles for Carboxylesterase 2c in the Intestine
Zhang_2019_Cells_8_395 An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis
Samokhvalov_2019_Front.Pharmacol_9_1572 Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation
Schurman_2019_J.Neurosci_39_5949 Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice
Rastogi_2019_J.Med.Microbiol_68_1629 Molecular characterization and immunogenic function of ML1899 (LipG) of Mycobacterium leprae
Ozturk_2019_Fungal.Biol_123_397 Evolutionary relics dominate the small number of secondary metabolism genes in the hemibiotrophic fungus Dothistroma septosporum
Sagong_2019_Biochem.Biophys.Res.Commun_517_399 Crystal structure and biochemical characterization of O-acetylhomoserine acetyltransferase from Mycobacterium smegmatis ATCC 19420
Komine-Aizawa_2019_Eur.J.Immunol_49_1399 MHC-restricted Ag85B-specific CD8(+) T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice
Chaton_2019_Sci.Rep_9_20267 Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site
Zhang_2019_J.Med.Chem_62_3575 Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II
Zhang_2019_Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban_50_291 [Mycobacterium Tuberculosis Rv3084 Encodes Functional Esterase and Suppresses the Pro-inflammatory Cytokines in vivo]
Santucci_2019_FEBS.J_286_3164 Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains
Burggraaf_2019_mBio_10_e01951 Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease
Maan_2019_Future.Microbiol_14_1397 Rv2223c, an acid inducible carboxyl-esterase of Mycobacterium tuberculosis enhanced the growth and survival of Mycobacterium smegmatis
Mazurkewich_2019_J.Biol.Chem_294_19978 Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components
Liang_2019_Biochem.Genet_57_403 Identification and Characterization of a Novel Strigolactone-Insensitive Mutant, Dwarfism with High Tillering Ability 34 (dhta-34) in Rice (Oryza sativa L.)
Zhao_2019_ACS.Catal_9_2916 How To Break the Janus Effect of H2O2 in Biocatalysis? Understanding Inactivation Mechanisms To Generate more Robust Enzymes
Phuengmaung_2019_Enzyme.Microb.Technol_131_109380 Identification and characterization of ferulic acid esterase from Penicillium chrysogenum 31B: de-esterification of ferulic acid decorated with l-arabinofuranoses and d-galactopyranoses in sugar beet pectin
Hamiaux_2019_Biochem.J_476_1843 Chemical synthesis and characterization of a new quinazolinedione competitive antagonist for strigolactone receptors with an unexpected binding mode
Burger_2019_Cell.Rep_26_855 Structural Basis of Karrikin and Non-natural Strigolactone Perception in Physcomitrella patens
Gilbert_2019_PeerJ_7_e6374 Genes of the pig, Sus scrofa, reconstructed with EvidentialGene
Heater_2019_Biotechnol.Biofuels_12_165 Directed evolution of a genetically encoded immobilized lipase for the efficient production of biodiesel from waste cooking oil
Bleffert_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_270 Pseudomonas aeruginosa esterase PA2949, a bacterial homolog of the human membrane esterase ABHD6: expression, purification and crystallization
do Canto_2019_J.Mol.Graph.Model_89_82 Polyurethanases: Three-dimensional structures and molecular dynamics simulations of enzymes that degrade polyurethane
Yaacob_2019_Comput.Struct.Biotechnol.J_17_215 Effects of Lid 1 Mutagenesis on Lid Displacement, Catalytic Performances and Thermostability of Cold-active Pseudomonas AMS8 Lipase in Toluene
Tratsiak_2019_Acta.Crystallogr.F.Struct.Biol.Commun_75_324 Crystal structure of the cold-adapted haloalkane dehalogenase DpcA from Psychrobacter cryohalolentis K5
Ellis-Guardiola_2019_Biochemistry_58_1616 Crystal Structure and Conformational Dynamics of Pyrococcus furiosus Prolyl Oligopeptidase
Yao_2019_Drug.Metab.Dispos_47_794 Enhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite
Moroz_2019_ACS.Omega_4_9964 Novel Inhibitory Function of the Rhizomucor miehei Lipase Propeptide and Three-Dimensional Structures of Its Complexes with the Enzyme
Zang_2019_J.Hazard.Mater__121684 Carboxylesterase, a de-esterification enzyme, catalyzes the degradation of chlorimuron-ethyl in Rhodococcus erythropolis D310-1
Mehrabi_2019_Science_365_1167 Time-resolved crystallography reveals allosteric communication aligned with molecular breathing
Mehrabi_2019_J.Am.Chem.Soc_141_11540 Substrate-Based Allosteric Regulation of a Homodimeric Enzyme
Wierman_2019_IUCrJ_6_305 Fixed-target serial oscillation crystallography at room temperature
Tedla_2019_PLoS.Pathog_15_e1008213 Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signaling and drug detoxification and are essential for parasite survival
Kellershohn_2019_PLoS.Negl.Trop.Dis_13_e0007240 Insects in anthelminthics research: Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni
Lee_2019_Microb.Cell.Fact_18_140 Structural and functional characterization of a novel cold-active S-formylglutathione hydrolase (SfSFGH) homolog from Shewanella frigidimarina, a psychrophilic bacterium
Alberts_2019_Toxins.(Basel)_11_523 Detoxification of the Fumonisin Mycotoxins in Maize: An Enzymatic Approach
Chen_2019_Proc.Natl.Acad.Sci.U.S.A_116_3764 Bacterial lipolysis of immune-activating ligands promotes evasion of innate defenses
Gricajeva_2019_Int.J.Biol.Macromol_130_253 Atypical organic-solvent tolerant bacterial hormone sensitive lipase-like homologue EstAG1 from Staphylococcus saprophyticus AG1: Synthesis and characterization
Zhou_2019_Sci.Rep_9_15564 Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences
Arnling Baath_2019_J.Biol.Chem_294_6635 Structure-function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds
Furukawa_2019_Sci.Rep_9_16038 Efficient Degradation of Poly(ethylene terephthalate) with Thermobifida fusca Cutinase Exhibiting Improved Catalytic Activity Generated using Mutagenesis and Additive-based Approaches
Tang_2019_Appl.Microbiol.Biotechnol_103_3037 Expression and characterization of two glucuronoyl esterases from Thielavia terrestris and their application in enzymatic hydrolysis of corn bran
Chalupova_2019_Eur.J.Med.Chem_168_491 Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
Lalut_2019_Eur.J.Med.Chem_162_234 Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1 receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase
Oukoloff_2019_Eur.J.Med.Chem_168_58 Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3
Wang_2019_PLoS.One_14_e0215084 Purification and biochemical characterization of FrsA protein from Vibrio vulnificus as an esterase
Jindal_2019_Proc.Natl.Acad.Sci.U.S.A_116_389 Exploring the challenges of computational enzyme design by rebuilding the active site of a dehalogenase
Fu_2019_J.Chromatogr.A_1603_15 One-step orientated immobilization of nanobodies and its application for immunoglobulin purification
Wang_2019_Curr.Microbiol_76_1161 Bacillus subtilis Spore Surface Display of Haloalkane Dehalogenase DhaA
Daud_2019_Mol.Biotechnol_61_477 A Novel Mini Protein Design of Haloalkane Dehalogenase
Zhang_2019_Int.J.Biol.Macromol_137_1190 Rational design of a Yarrowia lipolytica derived lipase for improved thermostability
Makino_2019_FEBS.Open.Bio_9_1337 Carboxypeptidase Y activity and maintenance is modulated by a large helical structure
Gowsalya_2019_Antonie.Van.Leeuwenhoek_112_1775 FSH1 overexpression triggers apoptosis in Saccharomyces cerevisiae
Gowsalya_2019_FEMS.Yeast.Res_19_ FSH3 mediated cell death is dependent on NUC1 in Saccharomyces cerevisiae
Duan_2019_Int.J.Biol.Macromol_135_768 High-level expression of codon-optimized Thielavia terrestris cutinase suitable for ester biosynthesis and biodegradation
Wei_2019_Pest.Manag.Sci_75_2166 Downregulation of carboxylesterase contributes to cyflumetofen resistance in Tetranychus cinnabarinus (Boisduval)
Mahajan_2019_Int.J.Biol.Macromol_122_806 Biodegradation of di-n-butyl phthalate by psychrotolerant Sphingobium yanoikuyae strain P4 and protein structural analysis of carboxylesterase involved in the pathway
Wei_2019_Pest.Manag.Sci_75_252 Functional analysis of four upregulated carboxylesterase genes associated with fenpropathrin resistance in Tetranychus cinnabarinus (Boisduval)
Cao_2019_J.Agric.Food.Chem_67_5189 Peach Carboxylesterase PpCXE1 Is Associated with Catabolism of Volatile Esters
Cao_2019_Front.Plant.Sci_10_1511 Genome-Wide Identification and Functional Analysis of Carboxylesterase and Methylesterase Gene Families in Peach (Prunus persica L. Batsch)
Wullich_2019_J.Struct.Biol_207_287 Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC, a mycobacterial dioxygenase of the alpha\/beta-hydrolase fold family
Senga_2019_J.Biochem_166_149 Metal binding to cutinase-like enzyme from Saccharomonospora viridis AHK190 and its effects on enzyme activity and stability
Nicolao_2019_PLoS.Negl.Trop.Dis_13_e0007032 Extracellular vesicles from Echinococcus granulosus larval stage: Isolation, characterization and uptake by dendritic cells
Kato_2019_Bioorg.Med.Chem.Lett_29_664 Substrate specificity of tuliposide-converting enzyme, a unique non-ester-hydrolyzing carboxylesterase in tulip: Effects of the alcohol moiety of substrate on the enzyme activity
Kim_2019_Arch.Biochem.Biophys_663_132 Characterization and mutation anaylsis of a cold-active bacterial hormone-sensitive lipase from Salinisphaera sp. P7-4
Kim_2019_PLoS.One_14_e0210298 Crystal structure of chloramphenicol-metabolizing enzyme EstDL136 from a metagenome
Jia_2019_Int.J.Biol.Macromol_126_1192 Expression and characterization of an esterase belonging to a new family via isolation from a metagenomic library of paper mill sludge
Zhao_2019_Anal.Cell.Pathol.(Amst)_2019_5901083 The Effect of Protein FAM172A on Proliferation in HepG2 Cells and Investigation of the Possible Molecular Mechanism
Hug_2019_J.Ind.Microbiol.Biotechnol_46_319 Genome mining reveals uncommon alkylpyrones as type III PKS products from myxobacteria
Elbers_2019_Mol.Ecol.Resour_19_1015 Improving Illumina assemblies with Hi-C and long reads: An example with the North African dromedary
Zan_2019_J.Agric.Food.Chem_67_13176 Novel Dual-Functional Enzyme Lip10 Catalyzes Lipase and Acyltransferase Activities in the Oleaginous Fungus Mucor circinelloides
Kaur_2019_Philos.Trans.R.Soc.Lond.B.Biol.Sci_374_20180192 Ant behaviour and brain gene expression of defending hosts depend on the ecological success of the intruding social parasite
Gomez Luciano_2019_Mol.Biol.Evol_36_1148 Blast Fungal Genomes Show Frequent Chromosomal Changes, Gene Gains and Losses, and Effector Gene Turnover
Liu_2019_Sci.China.Life.Sci_62_609 De novo assembly of white poplar genome and genetic diversity of white poplar population in Irtysh River basin in China
Chaw_2019_Nat.Plants_5_63 Stout camphor tree genome fills gaps in understanding of flowering plant genome evolution
Zou_2019_Nat.Commun_10_436 The genome of broomcorn millet
Armitage_2019_Front.Microbiol_10_3124 Genomics Evolutionary History and Diagnostics of the Alternaria alternata Species Group Including Apple and Asian Pear Pathotypes
Wielgoss_2019_Science_363_1342 Social genes are selection hotspots in kin groups of a soil microbe
Park_2019_Appl.Microbiol.Biotechnol_103_8145 Comprehensive genomic and transcriptomic analysis of polycyclic aromatic hydrocarbon degradation by a mycoremediation fungus, Dentipellis sp. KUC8613
Varga_2019_Nat.Ecol.Evol_3_668 Megaphylogeny resolves global patterns of mushroom evolution
Westbury_2019_IScience_15_592 Narwhal Genome Reveals Long-Term Low Genetic Diversity despite Current Large Abundance Size
Chen_2019_G3.(Bethesda)_9_2051 Sequencing of a Wild Apple (Malus baccata) Genome Unravels the Differences Between Cultivated and Wild Apple Species Regarding Disease Resistance and Cold Tolerance
Wang_2019_Nat.Plants_5_810 Musa balbisiana genome reveals subgenome evolution and functional divergence
Ming_2019_Genomics_111_1034 Molecular footprints of inshore aquatic adaptation in Indo-Pacific humpback dolphin (Sousa chinensis)
Nunez-Montero_2019_Sci.Rep_9_7488 Antarctic Streptomyces fildesensis So13.3 strain as a promising source for antimicrobials discovery
Mondo_2019_Biotechnol.Biofuels_12_229 Genome expansion by allopolyploidization in the fungal strain Coniochaeta 2T2.1 and its exceptional lignocellulolytic machinery
Lin_2019_Appl.Microbiol.Biotechnol_103_7111 Genome sequence of Isaria javanica and comparative genome analysis insights into family S53 peptidase evolution in fungal entomopathogens
Morishita_2019_Org.Lett_21_4788 The Discovery of Fungal Polyene Macrolides via a Postgenomic Approach Reveals a Polyketide Macrocyclization by trans-Acting Thioesterase in Fungi
Grover_2019_Genome.Biol.Evol_11_53 Insights into the Evolution of the New World Diploid Cottons (Gossypium, Subgenus Houzingenia) Based on Genome Sequencing
Yang_2019_Gigascience_8_giz085 De novo genome assembly of the endangered Acer yangbiense, a plant species with extremely small populations endemic to Yunnan Province, China
Carballo_2019_Sci.Rep_9_10250 A high-quality genome of Eragrostis curvula grass provides insights into Poaceae evolution and supports new strategies to enhance forage quality
Urquhart_2019_Fungal.Biol.Biotechnol_6_2 The fungal gene cluster for biosynthesis of the antibacterial agent viriditoxin
Obermaier_2019_Angew.Chem.Int.Ed.Engl_58_9125 Enantioselective Phenol Coupling by Laccases in the Biosynthesis of Fungal Dimeric Naphthopyrones
Hu_2019_Chem.Sci_10_1457 Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system
Qu_2019_Plant.J_97_257 Completion of the canonical pathway for assembly of anticancer drugs vincristine\/vinblastine in Catharanthus roseus
Araki_2019_Proc.Natl.Acad.Sci.U.S.A_116_8269 Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum
Obermaier_2019_Biochemistry_58_2589 Biaryl-Forming Enzymes from Aspergilli Exhibit Substrate-Dependent Stereoselectivity
Baldeweg_2019_Org.Lett_21_1444 Fungal Biosurfactants from Mortierella alpina
Zhang_2019_Mol.Microbiol_112_649 Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici
Lee_2019_Angew.Chem.Int.Ed.Engl_58_18414 The Biosynthesis of Norsesquiterpene Aculenes Requires Three Cytochrome P450 Enzymes to Catalyze a Stepwise Demethylation Process
Leu_2019_Am.J.Chin.Med_47_1365 Induction of Autophagic Death of Human Hepatocellular Carcinoma Cells by Armillaridin from Armillaria mellea
Steiniger_2019_Cell.Chem.Biol_26_1526 Probing Exchange Units for Combining Iterative and Linear Fungal Nonribosomal Peptide Synthetases
Xu_2019_J.Biol.Eng_13_65 Modified substrate specificity of a methyltransferase domain by protein insertion into an adenylation domain of the bassianolide synthetase
Kim_2019_MSphere_4_e003270 Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis
Fan_2019_J.Am.Chem.Soc_141_4225 Peniphenone and Penilactone Formation in Penicillium crustosum via 1,4-Michael Additions of ortho-Quinone Methide from Hydroxyclavatol to gamma-Butyrolactones from Crustosic Acid
Greco_2019_ACS.Chem.Biol_14_1121 Depsipeptide Aspergillicins Revealed by Chromatin Reader Protein Deletion
Kovacic_2019_Handb.Hydrocarbon.Lipid.Microbiol__255 Classification of Lipolytic Enzymes from Bacteria
Sinha_2019_J.Ind.Microbiol.Biotechnol_46_1217 The complete genomic sequence of Streptomyces spectabilis NRRL-2792 and identification of secondary metabolite biosynthetic gene clusters
Chevrette_2019_Nat.Commun_10_516 The antimicrobial potential of Streptomyces from insect microbiomes
Wu_2019_Int.J.Syst.Evol.Microbiol_69_895 The Global Catalogue of Microorganisms (GCM) 10K type strain sequencing project: providing services to taxonomists for standard genome sequencing and annotation
Alves_2019_Front.Microbiol_10_1571 Ammonia Oxidation by the Arctic Terrestrial Thaumarchaeote Candidatus Nitrosocosmicus arcticus Is Stimulated by Increasing Temperatures
Berni_2019_Front.Microbiol_10_1218 A Type VI Secretion System Trans-Kingdom Effector Is Required for the Delivery of a Novel Antibacterial Toxin in Pseudomonas aeruginosa
Gan_2019_Mol.Plant.Microbe.Interact_32_1088 Genome Sequence Resources for Four Phytopathogenic Fungi from the Colletotrichum orbiculare Species Complex
Lee_2019_Int.J.Syst.Evol.Microbiol_69_3148 Undibacterium piscinae sp. nov., isolated from Korean shiner intestine
Jia_2019_Plant.Biotechnol.J_17_397 The red bayberry genome and genetic basis of sex determination
Yoshida_2019_Curr.Biol_29_3041 Genome Sequence of Striga asiatica Provides Insight into the Evolution of Plant Parasitism
Matsumoto_2019_Emerg.Microbes.Infect_8_1043 Comprehensive subspecies identification of 175 nontuberculous mycobacteria species based on 7547 genomic profiles
Wilpiszeski_2019_Extremophiles_23_119 Biogeography of thermophiles and predominance of Thermus scotoductus in domestic water heaters
Oracz_2019_Pancreatology_19_531 The hybrid allele 1 of carboxyl-ester lipase (CEL-HYB1) in Polish pediatric patients with chronic pancreatitis
Qian_2019_Chem.Biol.Interact__108914 The influence of carboxylesterase 1 polymorphism and cannabidiol on the hepatic metabolism of heroin
Li_2019_Nat.Biomed.Eng_3_105 Genome-edited skin epidermal stem cells protect mice from cocaine-seeking behaviour and cocaine overdose
Chen_2019_Chem.Biol.Interact_13ChEPon_306_89 Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression
Atyame_2019_Proc.Biol.Sci_286_20182273 Insecticide resistance genes affect Culex quinquefasciatus vector competence for West Nile virus
Bkhache_2019_Pest.Manag.Sci_75_286 G119S ace-1 mutation conferring insecticide resistance detected in the Culex pipiens complex in Morocco
Silva_2019_Sci.Rep_9_11406 Transcriptomic analysis of insecticide resistance in the lymphatic filariasis vector Culex quinquefasciatus
Filali_2019_J.Vector.Borne.Dis_56_308 Entomological status of Anopheles sergentii and the first molecular investigation of its insecticide-resistant genes, kdr and ace-1 in Morocco
Elanga-Ndille_2019_Genes.(Basel)_10_ The G119S Acetylcholinesterase (Ace-1) Target Site Mutation Confers Carbamate Resistance in the Major Malaria Vector Anopheles gambiae from Cameroon: A Challenge for the Coming IRS Implementation
Fang_2019_Parasit.Vectors_12_396 Resistance to pyrethroid and organophosphate insecticides, and the geographical distribution and polymorphisms of target-site mutations in voltage-gated sodium channel and acetylcholinesterase 1 genes in Anopheles sinensis populations in Shanghai, China
Stica_2019_Malar.J_18_244 Characterizing the molecular and metabolic mechanisms of insecticide resistance in Anopheles gambiae in Faranah, Guinea
Collins_2019_Sci.Rep_9_8846 The relationship between insecticide resistance, mosquito age and malaria prevalence in Anopheles gambiae s.l. from Guinea
da Cruz_2019_Malar.J_18_120 Detection of alleles associated with resistance to chemical insecticide in the malaria vector Anopheles arabiensis in Santiago, Cabo Verde
Lv_2019_Clin.Lab_65_ A Case Report of Primary Neonatal Hypocholinesterase Caused by Homozygous Frameshift Mutation of the butyrylcholinesterase (BCHE) Gene and Review of Literature
Hester_2019_Chem.Res.Toxicol_32_1801 Engineering Dynamic Surface Peptide Networks on ButyrylcholinesteraseG117H for Enhanced Organophosphosphorus Anticholinesterase Catalysis
Nobre_2019_Insects_10_ A Re-Evaluation of Olive Fruit Fly Organophosphate-Resistant Ace Alleles in Iberia, and Field-Testing Population Effects after in-Practice Dimethoate Use
Grigorenko_2019_Chem.Biol.Interact_13ChEPon_306_138 Computer-designed active human butyrylcholinesterase double mutant with a new catalytic triad
Wong_2019_Appl.Microbiol.Biotechnol_103_8449 Metagenomic discovery of feruloyl esterases from rumen microflora
Wang_2019_Nat.Commun_10_810 The apocarotenoid metabolite zaxinone regulates growth and strigolactone biosynthesis in rice
Bhuvanendran_2019_Front.Neurosci_13_495 Embelin, a Potent Molecule for Alzheimer's Disease: A Proof of Concept From Blood-Brain Barrier Permeability, Acetylcholinesterase Inhibition and Molecular Docking Studies
Nuthakki_2019_Drug.Dev.Res_80_655 Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent
Rajeshwari_2019_Molecules_24_587 New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer's Disease
El-Sayed_2019_Bioorg.Chem_95_103499 New phosphazine and phosphazide derivatives as multifunctional ligands targeting acetylcholinesterase and beta-Amyloid aggregation for treatment of Alzheimer's disease
Sang_2019_ACS.Chem.Neurosci_10_1008 Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease
Eslami_2019_J.Biomol.Struct.Dyn__1 Computational approach to suggest a new multi-target-directed ligand as a potential medication for Alzheimer's disease
de Los Rios_2019_Eur.J.Med.Chem_166_381 Tacrines for Alzheimer's disease therapy. III. The PyridoTacrines
Barre_2019_Molecules_24_ Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy
Van den Houte_2019_Neurogastroenterol.Motil__e13544 Influence of itopride and domperidone on gastric tone and on the perception of gastric distention in healthy subjects
Riazimontazer_2019_Bioorg.Chem_89_103006 Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives
Vuksic_2019_Arh.Hig.Rada.Toksikol_70_30 Effects of simvastatin and fenofibrate on butyrylcholinesterase activity in the brain, plasma, and liver of normolipidemic and hyperlipidemic rats
Guan_2019_Chem.Commun.(Camb)_55_953 Enzyme-responsive sulfatocyclodextrin\/prodrug supramolecular assembly for controlled release of anti-cancer drug chlorambucil
Shi_2019_Sci.Rep_9_14997 A systemic study of indoxacarb resistance in Spodoptera litura revealed complex expression profiles and regulatory mechanism
Zhang_2019_Int.J.Biol.Macromol_140_358 Purification and characterization of a thermoalkaliphilic esterase from Bacillus cereus WZZ006 for enantioselective resolution of indoxacarb intermediate
Reisky_2019_Catalysts_9_64 A Novel High-Throughput Assay Enables the Direct Identification of Acyltransferases
Feng_2019_Fitoterapia__104378 Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity
Giessel_2019_Eur.J.Med.Chem_177_259 Caffeic acid phenethyl ester (CAPE)-derivatives act as selective inhibitors of acetylcholinesterase
Noh_2019_Appl.Microbiol.Biotechnol_103_2079 Microbial production of butyl butyrate, a flavor and fragrance compound
Elias_2019_Enzyme.Microb.Technol_130_109367 Effect of operative variables and kinetic study of butyl butyrate synthesis by Candida rugosa lipase activated by chitosan-reinforced nanocellulose derived from raw oil palm leaves
Cong_2019_3.Biotech_9_244 Synthesis of flavor esters by a novel lipase from Aspergillus niger in a soybean-solvent system
Morigny_2019_Nat.Metab_1_133 Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity
Montanari_2019_Eur.J.Med.Chem_178_243 Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment
Lu_2019_Bioorg.Chem_85_117 Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation
Komatsu_2019_Biochim.Biophys.Acta.Proteins.Proteom_1867_82 Development and validation of an improved diced electrophoresis gel assay cutter-plate system for enzymomics studies
Fernandes_2019_BMC.Anesthesiol_19_160 Failure of reversion of neuromuscular block with sugammadex in patient with myasthenia gravis: case report and brief review of literature
Chae_2019_J.Clin.Med_8_ Thirty-Day Postoperative Outcomes Following Sugammadex Use in Colorectal Surgery Patients\; Retrospective Study
Larsen_2019_Drug.Dev.Res_80_33 Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance
Phillips_2019_Toxicol.Sci_171_396 Inhibition of Human Liver Carboxylesterase (hCE1) by Organophosphate Ester Flame Retardants and Plasticizers: Implications for Pharmacotherapy
Shi_2019_Ecotoxicol.Environ.Saf_179_119 Acute exposure to triphenyl phosphate (TPhP) disturbs ocular development and muscular organization in zebrafish larvae
Gonzalez-Morales_2019_J.Econ.Entomol_112_786 Effect of Synergists on Deltamethrin Resistance in the Common Bed Bug (Hemiptera: Cimicidae)
Yuan_2019_Environ.Pollut_250_58 Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairment in A549 cells
Zhao_2019_Environ.Int_124_259 Urinary biomarkers for assessment of human exposure to monomeric aryl phosphate flame retardants
Wade_2019_Int.J.Toxicol_38_279 Toxicity of Flame Retardant Isopropylated Triphenyl Phosphate: Liver, Adrenal, and Metabolic Effects
Rial_2019_Phytochem.Anal_30_110 A new UHPLC-MS\/MS method for the direct determination of strigolactones in root exudates and extracts
Xie_2019_Phytochemistry_157_200 Lotuslactone, a non-canonical strigolactone from Lotus japonicus
Yasui_2019_Yakugaku.Zasshi_139_1259 [Construction of All-cis-substituted Cyclopropane and Total Synthesis of Avenaol]
Yoneyama_2019_Pest.Manag.Sci_75_2353 Regulation of biosynthesis, perception, and functions of strigolactones for promoting arbuscular mycorrhizal symbiosis and managing root parasitic weeds
Freyer_2019_Drug.Des.Devel.Ther_13_1033 Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system
Tripathi_2019_Eur.J.Med.Chem_183_111707 Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease
Mishra_2019_Bioorg.Chem_89_103025 Design and development of 1,3,4-oxadiazole derivatives as potential inhibitors of acetylcholinesterase to ameliorate scopolamine-induced cognitive dysfunctions
Arai_2019_J.Biosci.Bioeng_127_222 Structural characterization of hemicellulose released from corn cob in continuous flow type hydrothermal reactor
Song_2019_Int.J.Biol.Macromol_131_201 Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations
Gartung_2019_Proc.Natl.Acad.Sci.U.S.A_116_1698 Suppression of chemotherapy-induced cytokine\/lipid mediator surge and ovarian cancer by a dual COX-2\/sEH inhibitor
Dileepan_2019_Front.Pharmacol_10_1118 Effect Of Dual sEH\/COX-2 Inhibition on Allergen-Induced Airway Inflammation
Wakabayashi_2019_Sci.Adv_5_eaax9067 Direct conversion of carlactonoic acid to orobanchol by cytochrome P450 CYP722C in strigolactone biosynthesis
Wang_2019_Chembiochem_20_2212 Discovery and Evaluation of New Activity-Based Probes for Serine Hydrolases
Chen_2019_Angew.Chem.Int.Ed.Engl_58_5643 Fluorescent Triazole Urea Activity-Based Probes for the Single-Cell Phenotypic Characterization of Staphylococcus aureus
Konishi_2019_Biopharm.Drug.Dispos_40_176 Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment
Ezeoyili_2019_J.Aquat.Anim.Health_31_371 Changes in Brain Acetylcholinesterase and Oxidative Stress Biomarkers in African Catfish Exposed to Carbendazim
Silva_2019_Environ.Toxicol.Chem_38_412 Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level
Koshimichi_2019_J.Pharm.Sci_108_1896 Population Pharmacokinetic and Exposure-Response Analyses of Baloxavir Marboxil in Adults and Adolescents Including Patients With Influenza
Basa-Denes_2019_Eur.J.Pharm.Sci_129_79 Investigations of the mechanism behind the rapid absorption of nano-amorphous abiraterone acetate
Lv_2019_BMC.Neurol_19_114 Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population
Zhao_2019_Int.J.Clin.Pharm_41_1414 Association between EPHX1 polymorphisms and carbamazepine metabolism in epilepsy: a meta-analysis
Toselli_2019_J.Med.Chem_62_7383 Hip To Be Square: Oxetanes as Design Elements To Alter Metabolic Pathways
Li_2019_J.Ethnopharmacol_245_112185 Screening of acetylcholinesterase inhibitors and characterizing of phytochemical constituents from Dichocarpum auriculatum (Franch.) W.T. Wang & P. K. Hsiao through UPLC-MS combined with an acetylcholinesterase inhibition assay in vitro
Balkrishna_2019_Molecules_24_ Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study
Cassiano_2019_Comput.Biol.Chem_83_107129 Acetylcholinesterase inhibitory activities and bioguided fractionation of the Ocotea percoriacea extracts: HPLC-DAD-MS\/MS characterization and molecular modeling of their alkaloids in the active fraction
Liu_2019_J.Sep.Sci_42_1194 Large-scale separation of acetylcholinesterase inhibitors from Zanthoxylum nitidum by pH-zone-refining counter-current chromatography target-guided by ultrafiltration high-performance liquid chromatography with ultraviolet and mass spectrometry screening
Hostalkova_2019_J.Nat.Prod_82_239 Isoquinoline Alkaloids from Berberis vulgaris as Potential Lead Compounds for the Treatment of Alzheimer's Disease
Yuan_2019_BMC.Complement.Altern.Med_19_109 Neuroprotective effects of berberine in animal models of Alzheimer's disease: a systematic review of pre-clinical studies
Sadraie_2019_Metab.Brain.Dis_34_245 Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms
de Lima_2019_Front.Chem_7_629 Synthesis and Inhibition Evaluation of New Benzyltetrahydroprotoberberine Alkaloids Designed as Acetylcholinesterase Inhibitors
Wang_2019_Front.Pharmacol_10_1003 Berberine Ameliorates Spatial Learning Memory Impairment and Modulates Cholinergic Anti-Inflammatory Pathway in Diabetic Rats
Wei_2019_Nat.Commun_10_5581 Conformational fitting of a flexible oligomeric substrate does not explain the enzymatic PET degradation
Seo_2019_Nat.Commun_10_5582 Reply to 'Conformational fitting of a flexible oligomeric substrate does not explain the enzymatic PET degradation'
Hoffmann_2019_J.Med.Chem_62_9116 Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer's Disease Mouse Model
Jiang_2019_Phytomedicine_62_152967 Mechanism-based pharmacokinetics-pharmacodynamics studies of harmine and harmaline on neurotransmitters regulatory effects in healthy rats: Challenge on monoamine oxidase and acetylcholinesterase inhibition
Zhang_2019_Molecules_24_ Potential Pharmacokinetic Drug(-)Drug Interaction Between Harmine, a Cholinesterase Inhibitor, and Memantine, a Non-Competitive N-Methyl-d-Aspartate Receptor Antagonist
Merrill_2019_J.Biol.Chem_294_16164 A robust and economical pulse-chase protocol to measure the turnover of HaloTag fusion proteins
Lepore_2019_Sci.Rep_9_7902 Quantification of very low-abundant proteins in bacteria using the HaloTag and epi-fluorescence microscopy
da Luz Abreu_2019_Nutr.Metab.(Lond)_16_61 (3Z)-5-Chloro-3-(Hydroxyimino)indolin-2-one attenuates hyperglycemia, increased hepatic glycogen content and hepatic damage induced by malathion acute exposure in rats
Muangnoi_2019_Int.J.Mol.Sci_20_ Protective Effects of Curcumin Ester Prodrug, Curcumin Diethyl Disuccinate against H(2)O(2)-Induced Oxidative Stress in Human Retinal Pigment Epithelial Cells: Potential Therapeutic Avenues for Age-Related Macular Degeneration
Muangnoi_2019_Sci.Rep_9_11718 Curcumin diethyl disuccinate, a prodrug of curcumin, enhances anti-proliferative effect of curcumin against HepG2 cells via apoptosis induction
Liu_2019_Bioorg.Chem_90_103101 Demethylbellidifolin isolated from Swertia bimaculate against human carboxylesterase 2: Kinetics and interaction mechanism merged with docking simulations
Yi_2019_Int.J.Biol.Macromol_133_184 A natural inhibitor from Alisma orientale against human carboxylesterase 2: Kinetics, circular dichroism spectroscopic analysis, and docking simulation
Salazar_2019_Biochim.Biophys.Acta.Biomembr_1861_170 Membrane order and ionic strength modulation of the inhibition of the membrane-bound acetylcholinesterase by epigallocatechin3gallate
Aupperle-Lellbach_2019_J.Comp.Pathol_173_71 Characterization of 22 Canine Pancreatic Carcinomas and Review of Literature
Lai_2019_Nutrients_11_ Analysis of the Lipolytic Activity of Whole-Saliva and Site-Specific Secretions from the Oral Cavity of Healthy Adults
Nistanaki_2019_Angew.Chem.Int.Ed.Engl_58_1724 A Concise Total Synthesis of (+\/-)-Vibralactone
Siebert_2019_J.Sci.Food.Agric_99_6644 Hydrolysis of chlorogenic acid in apple juice using a p-coumaryl esterase of Rhizoctonia solani
Azizi_2019_Acc.Chem.Res_52_3029 Activity-Based Sensing of S-Depalmitoylases: Chemical Technologies and Biological Discovery
Zhang_2019_Ecotoxicol.Environ.Saf_183_109581 Transcriptomic analysis of Chlorimuron-ethyl degrading bacterial strain Klebsiella jilinsis 2N3
Zhang_2019_J.Pharm.Pharmacol_71_1291 Soluble epoxide hydrolase inhibitor, TUPS, attenuates isoproterenol\/angiotensin II-induced cardiac hypertrophy through mammalian target of rapamycin-mediated autophagy inhibition
Eissa_2019_Chem.Biol.Interact__108775 The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammation in sodium valproate induced autism in mice
Han_2019_Nutrients_11_ Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches
Torres-Villarreal_2019_J.Physiol.Biochem_75_83 Anti-obesity effects of kaempferol by inhibiting adipogenesis and increasing lipolysis in 3T3-L1 cells
Monroy-Noyola_2019_Chem.Biol.Interact_13ChEPon_310_108727 O-hexyl O-2,5-dichlorophenyl phosphoramidate as a substrate for domestic and sea bird serum A-esterases: Hydrolysis levels, Cu(2+)- and Zn(2+)-dependence and stereoselectivity
Song_2019_Fitoterapia_137_104199 Discovery of natural pentacyclic triterpenoids as potent and selective inhibitors against human carboxylesterase 1
Atkinson_2019_Medchemcomm_10_1361 Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen
Mutunga_2019_Int.J.Environ.Res.Public.Health_16_ Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates
Chlebek_2019_Molecules_24_ In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier
Moodie_2019_Nat.Prod.Rep_36_1053 Natural cholinesterase inhibitors from marine organisms
Bachurin_2019_Sci.Rep_9_4873 Conjugates of methylene blue with gamma-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases
Thierbach_2019_Beilstein.J.Org.Chem_15_187 Synthesis and biological activity of methylated derivatives of the Pseudomonas metabolites HHQ, HQNO and PQS
Gonzalez-Marquez_2019_Ecotoxicol.Environ.Saf_170_293 Biodegradation patterns of the endocrine disrupting pollutant di(2-ethyl hexyl) phthalate by Fusarium culmorum
Dong_2019_Food.Chem_283_508 Assessment of phthalate ester residues and distribution patterns in Baijiu raw materials and Baijiu
Li_2019_J.Pharm.Biomed.Anal_168_13 Role of esterase mediated hydrolysis of simvastatin in human and rat blood and its impact on pharmacokinetic profiles of simvastatin and its active metabolite in rat
Kovarik_2019_Chemistry_25_4100 Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase
Nakamura_2019_Mol.Plant_12_44 Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses
Imai_2019_J.Pharm.Sci_108_1027 Contribution of Human Liver and Intestinal Carboxylesterases to the Hydrolysis of Selexipag In Vitro
Kodani_2019_Biochimie_159_59 Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation
Bannehr_2019_Cardiovasc.Toxicol_19_365 Linoleic Acid Metabolite DiHOME Decreases Post-ischemic Cardiac Recovery in Murine Hearts
Yu_2019_Transl.Stroke.Res_10_522 Soluble Epoxide Hydrolase-Derived Linoleic Acid Oxylipins in Serum Are Associated with Periventricular White Matter Hyperintensities and Vascular Cognitive Impairment
Varasteh_2019_J.Nucl.Med_60_1743 Molecular Imaging of Fibroblast Activity After Myocardial Infarction Using a (68)Ga-Labeled Fibroblast Activation Protein Inhibitor, FAPI-04
Hildreth_2019_Curr.Dev.Nutr_3_ Soluble Epoxide Hydrolase Inhibitor t-AUCB Promotes Murine Brown Adipogenesis: Role of PPAR Gamma and PPAR Alpha (P21-069-19)
Liu_2019_Sci.Total.Environ_666_1106 Specific quorum sensing molecules of ammonia oxidizers and their role during ammonium metabolism in Zhalong wetland, China
Chen_2019_J.Med.Chem_62_8866 Design, Synthesis, and Evaluation of (18)F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes
Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154 Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK
Wu_2019_J.Mol.Neurosci_67_364 TPPU, a sEH Inhibitor, Attenuates Corticosterone-Induced PC12 Cell Injury by Modulation of BDNF-TrkB Pathway
Yao_2019_Am.J.Physiol.Gastrointest.Liver.Physiol_316_G527 Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing beta-oxidation of fatty acid in mice
Liang_2019_ACS.Chem.Neurosci_10_4018 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells
Hashimoto_2019_Curr.Psychiatry.Rep_21_75 Recent Advances in the Early Intervention in Schizophrenia: Future Direction from Preclinical Findings
Wang_2019_Front.Aging.Neurosci_11_3 Effects of BIS-MEP on Reversing Amyloid Plaque Deposition and Spatial Learning and Memory Impairments in a Mouse Model of beta-Amyloid Peptide- and Ibotenic Acid-Induced Alzheimer's Disease
Fronza_2019_Sci.Rep_9_7276 Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer's disease
Singhal_2019_Mol.Pharm_16_3460 Controlled Iontophoretic Delivery in Vitro and in Vivo of ARN14140-A Multitarget Compound for Alzheimer's Disease
Perez-Areales_2019_Eur.J.Med.Chem_180_613 A novel class of multitarget anti-Alzheimer benzohomoadamantanechlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors
Pang_2019_Mol.Med.Rep_20_1103 Pharmacokinetics, excretion and metabolites analysis of DL0410, a dualacting cholinesterase inhibitor and histamine3 receptor antagonist
Kaniakova_2019_Curr.Alzheimer.Res_16_821 Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer's Disease
Jia_2019_Biomed.Pharmacother_115_108906 Vicagrel enhances aspirin-induced inhibition of both platelet aggregation and thrombus formation in rodents due to its decreased metabolic inactivation
Venturini_2019_Fish.Physiol.Biochem_45_341 A multi-biomarker approach to lambda-cyhalothrin effects on the freshwater teleost matrinxa Brycon amazonicus: single-pulse exposure and recovery
Hedges_2019_Xenobiotica_49_388 Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations
Hedges_2019_Xenobiotica_49_521 Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes
de Saint Germain_2019_Phytochemistry_168_112112 Contalactone, a contaminant formed during chemical synthesis of the strigolactone reference GR24 is also a strigolactone mimic
Duan_2019_Proc.Natl.Acad.Sci.U.S.A_116_14319 Strigolactone promotes cytokinin degradation through transcriptional activation of CYTOKININ OXIDASE\/DEHYDROGENASE 9 in rice
Tian_2019_Anal.Chem_91_5638 Rational Design of a Long-Wavelength Fluorescent Probe for Highly Selective Sensing of Carboxylesterase 1 in Living Systems
Yan_2019_ACS.Chem.Neurosci_10_2903 Selenepezil, a Selenium-Containing Compound, Exerts Neuroprotective Effect via Modulation of the Keap1-Nrf2-ARE Pathway and Attenuates Abeta-Induced Cognitive Impairment in Vivo
Kawai_2019_Appl.Microbiol.Biotechnol_103_4253 Current knowledge on enzymatic PET degradation and its possible application to waste stream management and other fields
Moog_2019_Microb.Cell.Fact_18_171 Using a marine microalga as a chassis for polyethylene terephthalate (PET) degradation
Danso_2019_Appl.Environ.Microbiol_85_e01095 Plastics: Environmental and Biotechnological Perspectives on Microbial Degradation
Magnin_2019_Waste.Manag_85_141 Enzymatic recycling of thermoplastic polyurethanes: Synergistic effect of an esterase and an amidase and recovery of building blocks
Gan_2019_Database.(Oxford)_2019_bav119 PMBD: a Comprehensive Plastics Microbial Biodegradation Database
Oliveira_2019_Bioresour.Technol_278_408 Feruloyl esterases: Biocatalysts to overcome biomass recalcitrance and for the production of bioactive compounds
Habib_2019_Gut_68_522 Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver
McReynolds_2019_Front.Pharmacol_10_533 Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis
Onder_2019_Chem.Biol.Interact_314_108845 The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by methylene violet 3RAX
Wang_2019_ACS.Catalysis_9_2292 Covalent Inhibition Mechanism of Antidiabetic DrugsVildagliptin vs Saxagliptin
Plescia_2019_J.Med.Chem_62_7874 Integrated Synthetic, Biophysical, and Computational Investigations of Covalent Inhibitors of Prolyl Oligopeptidase and Fibroblast Activation Protein alpha
Mirzaev_2019_Drug.Metab.Pers.Ther_34_ Effects of the rs2244613 polymorphism of the CES1 gene on the antiplatelet effect of the receptor P2Y12 blocker clopidogrel
Wang_2019_Chem.Biol.Interact__108871 Interspecies variation of clopidogrel hydrolysis in liver microsomes from various manmmals
Meena_2019_Mol.Pharm_16_2296 Potent Acetylcholinesterase Selective and Reversible Homodimeric Agent Based on Tacrine for Theranostics
Ali_2019_Int.J.Mol.Sci_20_ Identification and Evaluation of Inhibitors of Lipase from Malassezia restricta using Virtual High-Throughput Screening and Molecular Dynamics Studies
Chen_2019_Nat.Chem.Biol_15_453 Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan
Dallares_2019_J.Toxicol.Environ.Health.A__1 Preliminary results on the uptake and biochemical response to water-exposure of Tamiflu(R) (oseltamivir phosphate) in two marine bivalves
Zhang_2019_J.Ethnopharmacol__112097 Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs
Vitorovic-Todorovic_2019_Chem.Biol.Interact_13ChEPon_309_108714 The in vitro protective effects of the three novel nanomolar reversible inhibitors of human cholinesterases against irreversible inhibition by organophosphorous chemical warfare agents
de Almeida_2019_Chem.Biol.Interact_13ChEPon_308_113 Surface screening, molecular modeling and in vitro studies on the interactions of aflatoxin M1 and human enzymes acetyl- and butyrylcholinesterase
Franca_2019_Int.J.Mol.Sci_20_ Novichoks: The Dangerous Fourth Generation of Chemical Weapons
Castelvecchi_2019_Nature__ Novichok nerve agents banned by chemical-weapons treaty
Gao_2019_Environ.Int_127_694 A potential biomarker of isofenphos-methyl in humans: A chiral view
Szwajgier_2019_Curr.Alzheimer.Res_16_963 Terpenes and Phenylpropanoids as Acetyl- and Butyrylcholinesterase Inhibitors: A Comparative Study
da Silva_2019_J.Enzyme.Inhib.Med.Chem_34_1018 Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approach
da Silva_2019_Chem.Biol.Interact_13ChEPon_307_195 Molecular modelling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime with VX-inhibited human acetylcholinesterase. A near attack approach to assess different spacer-lengths
Yao_2019_Biosens.Bioelectron_145_111705 Ratiometric fluorescence sensor for organophosphorus pesticide detection based on opposite responses of two fluorescence reagents to MnO2 nanosheets
Cavalcante_2019_Chem.Biol.Interact_13ChEPon_309_108682 Synthesis and in vitro evaluation of neutral aryloximes as reactivators of Electrophorus eel acetylcholinesterase inhibited by NEMP, a VX surrogate
Brinch_2019_Acta.Anaesthesiologica.Scandinavica_63_564 Reversal of mivacurium-induced neuromuscular blockade with a cholinesterase inhibitor: A systematic review
Hsueh_2019_Cell.Transplant__963689719854693 (-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice
Obara_2019_J.Pharmacol.Sci_140_197 Characterization of binding of antipsychotics to muscarinic receptors using mouse cerebral cortex
Barboza_2019_Sci.Rep_9_2481 Cholinergic Stimulation by Pyridostigmine Bromide Before Myocardial Infarction Prevent Cardiac and Autonomic Dysfunction
Bruun_2019_Neurotoxicol_73_81 Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication
Azzolin_2019_Toxicol.In.Vitro_60_237 The Val16Ala-SOD2 polymorphism affects cyto-genotoxicity of pyridostigmine bromide on human peripheral blood mononuclear cells
Macht_2019_Brain.Behav.Immun_80_384 Pyridostigmine bromide and stress interact to impact immune function, cholinergic neurochemistry and behavior in a rat model of Gulf War Illness
Okamoto_2019_Hypertension_73_235 Synergistic Pressor Effect of Atomoxetine and Pyridostigmine in Patients With Neurogenic Orthostatic Hypotension
Malabaey_2019_Am.J.Case.Rep_20_1418 Pyridostigmine Suicidal Attempt in a Myasthenia Gravis Patient
Nardo_2019_J.Neurogastroenterol.Motil_25_508 Pyridostigmine in Pediatric Intestinal Pseudo-obstruction: Case Report of a 2-year Old Girl and Literature Review
Vanhaesebrouck_2019_Brain_142_3713 beta2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure
Robinson-Papp_2019_J.Neurovirol_25_551 The effect of pyridostigmine on small intestinal bacterial overgrowth (SIBO) and plasma inflammatory biomarkers in HIV-associated autonomic neuropathies
Xue_2019_Free.Radic.Biol.Med_134_119 Pyridostigmine alleviates cardiac dysfunction via improving mitochondrial cristae shape in a mouse model of metabolic syndrome
Zhou_2019_Chem.Biol.Interact_13ChEPon_308_372 Structure-based virtual screening leading to discovery of highly selective butyrylcholinesterase inhibitors with solanaceous alkaloid scaffolds
Li_2019_Chemosphere_220_811 The adverse effect of TCIPP and TCEP on neurodevelopment of zebrafish embryos\/larvae
Matowo_2019_Parasit.Vectors_12_413 Fine-scale spatial and temporal variations in insecticide resistance in Culex pipiens complex mosquitoes in rural south-eastern Tanzania
Ma_2019_Pestic.Biochem.Physiol_157_204 Overexpression of multiple cytochrome P450 genes associated with sulfoxaflor resistance in Aphis gossypii Glover
Estevez_2019_Arch.Toxicol_93_1281 Interactions of human butyrylcholinesterase with phenylvalerate and acetylthiocholine as substrates and inhibitors: kinetic and molecular modeling approaches
Zhou_2019_ACS.Chem.Biol_14_164 Activity-Based Protein Profiling Identifies alpha-Ketoamides as Inhibitors for Phospholipase A2 Group XVI
Iqbal_2019_Chem.Biol.Interact_13ChEPon_310_108735 Reactivation potency of two novel oximes (K456 and K733) against paraoxon-inhibited acetyl and butyrylcholinesterase: In silico and in vitro models
Tekes_2019_Chem.Biol.Interact_13ChEPon_310_108737 Pharmacokinetics of K117 and K127, two novel antidote candidates to treat Tabun poisoning
Lorke_2019_Front.Neurosci_13_427 The Experimental Oxime K027-A Promising Protector From Organophosphate Pesticide Poisoning. A Review Comparing K027, K048, Pralidoxime, and Obidoxime
Jacevic_2019_Chem.Biol.Interact_13ChEPon_308_312 Interspecies and intergender differences in acute toxicity of K-oximes drug candidates
Antonijevic_2019_Chem.Biol.Interact_13ChEPon_308_385 Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation
Polisel_2019_Chem.Biol.Interact_13ChEPon_309_108671 Slight difference in the isomeric oximes K206 and K203 makes huge difference for the reactivation of organophosphorus-inhibited AChE: Theoretical and experimental aspects
Gorecki_2019_Arch.Toxicol_93_673 Oxime K203: a drug candidate for the treatment of tabun intoxication
Taylor_2019_Chem.Biol.Interact_13ChEPon_308_194 Assessment of ionizable, zwitterionic oximes as reactivating antidotal agents for organophosphate exposure
Savic_2019_Food.Chem_271_469 UV-C light irradiation enhances toxic effects of chlorpyrifos and its formulations
Wojdylo_2019_Food.Chem_271_216 Anticholinergic effects of Actinidia arguta fruits and their polyphenol content determined by liquid chromatography-photodiode array detector-quadrupole\/time of flight-mass spectrometry (LC-MS-PDA-Q\/TOF)
Golub_2019_Behav.Brain.Res_356_243 Role of hypothalamus-pituitary-adrenal axis modulation in the stress-resilient phenotype of DPP4-deficient rats
Yu_2019_Food.Chem_271_445 Lipase-catalyzed solvent-free synthesis of erythorbyl laurate in a gas-solid-liquid multiphase system
Abis_2019_Protein.Expr.Purif_153_105 Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain
Zhang_2019_Food.Chem_274_305 High-level expression of Aspergillus niger lipase in Pichia pastoris: Characterization and gastric digestion in vitro
Antonopoulou_2019_Enzyme.Microb.Technol_120_124 Screening of novel feruloyl esterases from Talaromyces wortmannii for the development of efficient and sustainable syntheses of feruloyl derivatives
Kangur_2019_Biochim.Biophys.Acta.Proteins.Proteom_1867_107 Structural Stability of Human Butyrylcholinesterase under High Hydrostatic Pressure
Karimi_2019_Cell.J_20_477 Vildagliptin Enhances Differentiation of Insulin Producing Cells from Adipose-Derived Mesenchymal Stem Cells
Yates_2019_Food.Chem_276_768 Determination of sinapine in rapeseed pomace extract: Its antioxidant and acetylcholinesterase inhibition properties
Gao_2019_J.Enzyme.Inhib.Med.Chem_34_150 Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors
Muthuraman_2019_Front.Biosci.(Elite.Ed)_11_109 Curcumin prevents cigarette smoke extract induced cognitive impairment
Berwaldt_2019_J.Enzyme.Inhib.Med.Chem_34_197 Synthesis and biological evaluation of benzothiazin-4-ones: a possible new class of acetylcholinesterase inhibitors
Dgachi_2019_J.Enzyme.Inhib.Med.Chem_34_163 Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy
Agatonovic-Kustrin_2019_Neural.Regen.Res_14_441 Essential oils and functional herbs for healthy aging
Ferrati_2019_Biomed.Pharmacother_109_1052 Protective and reversal actions of a novel peptidomimetic against a pivotal toxin implicated in Alzheimer's disease
Hassan_2019_Biomed.Pharmacother_109_2513 The exploration of novel Alzheimer's therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approaches
Ibrahim_2019_Neural.Regen.Res_14_437 Multitarget therapeutic strategies for Alzheimer's disease
Jayasingh_2019_Biomed.Pharmacother_109_1454 Neuroprotective effects of 1`delta-1`-acetoxyeugenol acetate on Abeta(25-35) induced cognitive dysfunction in mice
Akintunde_2019_Biochem.Biophys.Rep_17_97 Metabolic treatment of syndrome linked with Parkinson's disease and hypothalamus pituitary gonadal hormones by turmeric curcumin in Bisphenol-A induced neuro-testicular dysfunction of wistar rat
Hampel_2019_J.Prev.Alzheimers.Dis_6_2 Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research
de la Tremblaye_2019_Neuropharmacol_145_13 Environmental enrichment, alone or in combination with various pharmacotherapies, confers marked benefits after traumatic brain injury
Machal_2019_Curr.Vasc.Pharmacol_17_35 Efficacy of P2Y12 Receptor Blockers After Myocardial Infarction and Genetic Variability of their Metabolic Pathways
Tsoi_2019_Clin.Pharmacol.Ther_105_121 Monotherapy Is Good Enough for Patients with Mild-to-Moderate Alzheimer's Disease: A Network Meta-analysis of 76 Randomized Controlled Trials
Wein_2019_Curr.Comput.Aided.Drug.Des_15_104 New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling
Lorke_2019_J.Appl.Toxicol_39_101 Reversible cholinesterase inhibitors as pretreatment for exposure to organophosphates. A review
Guzel_2019_Arch.Pharm.(Weinheim)__e1800292 Aminopyrazole-substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties
Ilic_2019_PLoS.One_14_e0209999 Multifaceted activity of millipede secretions: Antioxidant, antineurodegenerative, and anti-Fusarium effects of the defensive secretions of Pachyiulus hungaricus (Karsch, 1881) and Megaphyllum unilineatum (C. L. Koch, 1838) (Diplopoda: Julida)
Imig_2019_Acta.Physiol.(Oxf)_225_e13203 Epigenetic soluble epoxide hydrolase regulation causes endothelial dysfunction
Ivanov_2019_Talanta_194_723 Electrochemical biosensor based on polyelectrolyte complexes for the determination of reversible inhibitors of acetylcholinesterase
Kawahara_2019_In.Vivo_33_239 Anthropometric Assessment After Proctocolectomy Due to Ulcerative Colitis
Keles_2019_Turk.Neurosurg_29_110 Effect of Axonal Length on Direct Neuromuscular Neurotization: An Experimental Study
Lajmanovich_2019_Chemosphere_220_714 Insecticide pyriproxyfen (Dragon((R))) damage biotransformation, thyroid hormones, heart rate, and swimming performance of Odontophrynus americanus tadpoles
Liu_2019_Clin.Chim.Acta_490_142 Pediatric reference intervals of liver and renal function tests from birth to adolescence in Chinese children as performed on the Olympus AU5400
Maharramov_2019_Arch.Pharm.(Weinheim)__e1800317 Synthesis, crystal structure, and biological evaluation of optically active 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-3-carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials
Sharma_2019_Mater.Sci.Eng.C.Mater.Biol.Appl_96_183 Preparation, characterization and evaluation of the zinc titanate and silver nitrate incorporated wipes for topical chemical and biological decontamination
Siebert_2019_Nat.Prod.Res__1 Determination of acetylcholinesterase and alpha-glucosidase inhibition by electrophoretically-mediated microanalysis and phenolic profile by HPLC-ESI-MS\/MS of fruit juices from Brazilian Myrtaceae Plinia cauliflora (Mart.) Kausel and Eugenia uniflora L
Sivabalakrishnan_2019_Parasit.Vectors_12_13 Susceptibility to common insecticides and detoxifying enzyme activities in Anopheles sundaicus (sensu lato) after cessation of indoor residual spraying of insecticides in the Jaffna Peninsula and its surroundings in northern Sri Lanka
Suo_2019_Mater.Sci.Eng.C.Mater.Biol.Appl_96_356 Synthesis of functional ionic liquid modified magnetic chitosan nanoparticles for porcine pancreatic lipase immobilization
Vasconez_2019_Acta.Physiol.(Oxf)_225_e13168 The histone demethylase Jarid1b mediates angiotensin II-induced endothelial dysfunction by controlling the 3'UTR of soluble epoxide hydrolase
Alak_2019_Chemosphere_221_30 Therapeutic effect of N- acetyl cysteine as an antioxidant on rainbow trout's brain in cypermethrin toxicity
Boran_2019_3.Biotech_9_5 Characterisation of Streptomyces violascens OC125-8 lipase for oily wastewater treatment
Burmaoglu_2019_Bioorg.Chem_85_191 Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and alpha-glycosidase inhibitors
Galal_2019_Ecotoxicol.Environ.Saf_171_502 Protective effect of N-acetylcysteine on fenitrothion-induced toxicity: The antioxidant status and metabolizing enzymes expression in rats
He_2019_Food.Chem_280_286 Candida sp. 99-125 lipase-catalyzed synthesis of ergosterol linolenate and its characterization
Hiesinger_2019_Prostaglandins.Other.Lipid.Mediat_140_31 Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity
Islam_2019_Environ.Int_123_428 Targeting microplastic particles in the void of diluted suspensions
Liargkova_2019_Molecules_24_ Small Multitarget Molecules Incorporating the Enone Moiety
Madav_2019_Brain.Res.Bull_146_171 Recent therapeutic strategies targeting beta amyloid and tauopathies in Alzheimer's disease
Nabi_2019_Nutr.Cancer__1 Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma
Prent-Penaloza_2019_Molecules_24_ Synthesis of diN-Substituted Glycyl-Phenylalanine Derivatives by Using Ugi Four Component Reaction and Their Potential as Acetylcholinesterase Inhibitors
Saidani_2019_Aquat.Toxicol_208_71 Metal accumulation, biochemical and behavioral responses on the Mediterranean clams Ruditapes decussatus exposed to two photocatalyst nanocomposites (TiO2 NPs and AuTiO2NPs)
Saleem_2019_J.Pharm.Biomed.Anal_166_128 Investigations into the therapeutic effects of aerial and stem parts of Buxus papillosa C.K. Schneid.: In vitro chemical, biological and toxicological perspectives
Schopfer_2019_PLoS.One_14_e0209795 Purification of human butyrylcholinesterase from frozen Cohn fraction IV-4 by ion exchange and Hupresin affinity chromatography
Song_2019_Int.J.Environ.Res.Public.Health_16_ Bisphenol A Exposure and Sperm ACHE Hydroxymethylation in Men
Townsend_2019_FASEB.J__fj201802048RR Loss of glucagon signaling alters white adipose tissue browning
Wang_2019_Drug.Des.Devel.Ther_13_243 Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX\/BCL2 ratio via mTOR pathway
Zarriello_2019_Prog.Neurobiol_172_23 Humble beginnings with big goals: Small molecule soluble epoxide hydrolase inhibitors for treating CNS disorders
Zhang_2019_Phytochemistry_159_199 Cholinesterase inhibitory isoquinoline alkaloids from Corydalis mucronifera
Ali_2019_Mol.Clin.Oncol_10_118 A multi-center retrospective analysis of the effect of DPP4 inhibitors on progression-free survival in advanced airway and colorectal cancers
Anderson_2019_CNS.Spectr__1 State of the science on mild cognitive impairment (MCI)
Bachmann_2019_Transl.Psychiatry_9_29 Behavioral training rescues motor deficits in Cyfip1 haploinsufficiency mouse model of autism spectrum disorders
Ding_2019_Biosci.Biotechnol.Biochem__1 Lipase-catalyzed synthesis of ethyl (R)-2-benzyloxy-2-isopropylhydrogenmalonate: a useful combination of chemical synthesis with enzymatic methods
Green_2019_Microb.Cell.Fact_18_10 Engineering the flagellar type III secretion system: improving capacity for secretion of recombinant protein
Hu_2019_Ecotoxicol.Environ.Saf_171_871 Effects of cadmium on fecundity and defence ability of Drosophila melanogaster
Kandiah_2019_CNS.Neurosci.Ther_25_288 Treatment of dementia and mild cognitive impairment with or without cerebrovascular disease: Expert consensus on the use of Ginkgo biloba extract, EGb 761((R))
Karakaya_2019_Nat.Prod.Res__1 The natural phenolic compounds and their antioxidant and anticholinesterase potential of herb Leiotulus dasyanthus (K. Koch) Pimenov &\; Ostr
Lee_2019_Environ.Res_171_161 Identification of metabolic pathways related to the bisphenol A-induced adipogenesis in differentiated murine adipocytes by using RNA-sequencing
Lu_2019_Int.J.Mol.Sci_20_ A Novel Dipeptidyl Peptidase IV Inhibitory Tea Peptide Improves Pancreatic beta-Cell Function and Reduces alpha-Cell Proliferation in Streptozotocin-Induced Diabetic Mice
Luo_2019_Nat.Prod.Res__1 A new diterpenoid alkaloid from Aconitum hemsleyanum
Mathew_2019_Arch.Pharm.(Weinheim)__e1800309 Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole
Parsons_2019_BMC.Palliat.Care_18_6 Caregivers' perspectives and experiences of withdrawing acetylcholinesterase inhibitors and memantine in advanced dementia: a qualitative analysis of an online discussion forum
Sridhar_2019_Bioorg.Chem_85_373 Design, synthesis, biological evaluation and molecular modelling studies of indole glyoxylamides as a new class of potential pancreatic lipase inhibitors
Vieider_2019_ACS.Med.Chem.Lett_10_62 Synthesis, Biological Evaluation and Structure-Activity Relationships of Diflapolin Analogues as Dual sEH\/FLAP Inhibitors
Yang_2019_J.Gene.Med__e3071 Association between the LIPG polymorphisms and serum lipid levels in the Maonan and Han populations
Bali_2019_Toxicology_415_18 Learning and memory impairments associated to acetylcholinesterase inhibition and oxidative stress following glyphosate based-herbicide exposure in mice
Botta_2019_Atherosclerosis_282_45 Deciphering the role of V200A and N291S mutations leading to LPL deficiency
Czarnecka_2019_Int.J.Mol.Sci_20_ Discovery of New Cyclopentaquinoline Analogues as Multifunctional Agents for the Treatment of Alzheimer's Disease
Fuhrimann_2019_JMIR.Res.Protoc_8_e10914 Exposure to Pesticides and Health Effects on Farm Owners and Workers From Conventional and Organic Agricultural Farms in Costa Rica: Protocol for a Cross-Sectional Study
Gonzalez-Naranjo_2019_Eur.J.Med.Chem_166_90 Indazolylketones as new multitarget cannabinoid drugs
Hatami_2019_Chemosphere_219_981 Sub-lethal toxicity of chlorpyrifos alone and in combination with polyethylene glycol to common carp (Cyprinus carpio)
Huang_2019_Int.J.Mol.Sci_20_ Polyalthia Clerodane Diterpene Potentiates Hypoglycemia via Inhibition of Dipeptidyl Peptidase 4
Islam_2019_Sci.Rep_9_276 Microfluidic-based graphene field effect transistor for femtomolar detection of chlorpyrifos
Jin_2019_Neural.Regen.Res_14_805 Comparative efficacy and safety of cognitive enhancers for treating vascular cognitive impairment: systematic review and Bayesian network meta-analysis
Kowal_2019_Molecules_24_ Novel Approach for the Search for Chemical Scaffolds with Dual Activity with Acetylcholinesterase and the alpha7 Nicotinic Acetylcholine Receptor-A Perspective for the Treatment of Neurodegenerative Disorders
Mousa_2019_Neural.Regen.Res_14_745 Repositioning of dipeptidyl peptidase-4 inhibitors and glucagon like peptide-1 agonists as potential neuroprotective agents
Muckova_2019_Toxicol.In.Vitro_56_110 Oxidative stress induced by oxime reactivators of acetylcholinesterase in vitro
Neerland_2019_BMC.Geriatr_19_23 Autonomic cardiovascular control in older patients with acute infection and delirium: a pilot study of orthostatic stress responses
Nkoom_2019_Ecotoxicol.Environ.Saf_172_11 Bioconcentration of the antiepileptic drug carbamazepine and its physiological and biochemical effects on Daphnia magna
Nwidu_2019_Medicines.(Basel)_6_ An Investigation of Potential Sources of Nutraceuticals from the Niger Delta Areas, Nigeria for Attenuating Oxidative Stress
Ramos_2019_Pharmaceuticals.(Basel)_12_ Identification of Potential Inhibitors from Pyriproxyfen with Insecticidal Activity by Virtual Screening
Rothenberg_2019_Curr.Treat.Options.Neurol_21_3 Advances in Management of Psychosis in Neurodegenerative Diseases
Saad-Hussein_2019_Mutat.Res_838_46 Early prediction of liver carcinogenicity due to occupational exposure to pesticides
Sohn_2019_Molecules_24_ Hwangryunhaedok-Tang Exerts Neuropreventive Effect on Memory Impairment by Reducing Cholinergic System Dysfunction and Inflammatory Response in a Vascular Dementia Rat Model
Trombini_2019_Aquat.Toxicol_208_146 Assessing the effect of human pharmaceuticals (carbamazepine, diclofenac and ibuprofen) on the marine clam Ruditapes philippinarum: An integrative and multibiomarker approach
Wang_2019_Sci.Rep_9_411 Toxicity and possible mechanisms of action of honokiol from Magnolia denudata seeds against four mosquito species
Xu_2019_Neural.Regen.Res_14_794 Kai Xin San ameliorates scopolamine-induced cognitive dysfunction
Downs_2019_Neurobiol.Dis_125_115 Trihexyphenidyl rescues the deficit in dopamine neurotransmission in a mouse model of DYT1 dystonia
Franco_2019_Chemosphere_222_175 Exposure to dilute concentrations of bupropion affects zebrafish early life stages
Galal_2019_Neurotoxicol_72_15 Modulation of caspase-3 gene expression and protective effects of garlic and spirulina against CNS neurotoxicity induced by lead exposure in male rats
Herbert_2019_Clin.Toxicol.(Phila)__1 COPD and asthma therapeutics for supportive treatment in organophosphate poisoning
Kloske_2019_Chemosphere_221_672 Novichoks - The A group of organophosphorus chemical warfare agents
Lee_2019_Mar.Drugs_17_ Dual BACE1 and Cholinesterase Inhibitory Effects of Phlorotannins from Ecklonia cava-An In Vitro and in Silico Study
Luderwald_2019_Sci.Total.Environ_663_518 A blessing in disguise? Natural organic matter reduces the UV light-induced toxicity of nanoparticulate titanium dioxide
Moerke_2019_Drug.Dev.Ind.Pharm__1 Nicotine-like discriminative stimulus effects of acetylcholinesterase inhibitors and a muscarinic receptor agonist in rhesus monkeys
Nanda_2019_Aquat.Toxicol_209_49 Detoxification mechanism of organophosphorus pesticide via carboxylestrase pathway that triggers de novo TAG biosynthesis in oleaginous microalgae
Pachon-Angona_2019_J.Enzyme.Inhib.Med.Chem_34_479 Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy
Pedersen_2019_BMC.Evol.Biol_19_38 Evolution of vertebrate nicotinic acetylcholine receptors
Santos_2019_Ecotoxicol.Environ.Saf_172_246 Assay optimisation and age-related baseline variation in biochemical markers in Lesser Black-backed gulls
Szczybelski_2019_Sci.Total.Environ_662_631 Biomarker responses and biotransformation capacity in Arctic and temperate benthic species exposed to polycyclic aromatic hydrocarbons
Wan_2019_J.Biomol.Struct.Dyn__1 Structural Basis of Fullerene Derivatives as Novel Potent Inhibitors of Protein Acetylcholinesterase without Catalytic Active Site Interaction: Insight into the Inhibitory Mechanism through Molecular Modeling Studies
Yamamoto_2019_Anticancer.Res_39_1085 Combination of Serum Albumin and Cholinesterase Levels as Prognostic Indicator in Patients ith Colorectal Cancer
Yang_2019_Nat.Prod.Res__1 Fluevirines E and F, two new alkaloids from Flueggea virosa
Zhao_2019_Evid.Based.Complement.Alternat.Med_2019_7365841 Treatment Effects of Jinlingzi Powder and Its Extractive Components on Gastric Ulcer Induced by Acetic Acid in Rats
Basirun_2019_3.Biotech_9_64 In vivo and in vitro effects on cholinesterase of blood of Oreochromis mossambicus by copper
Cavdar_2019_J.Enzyme.Inhib.Med.Chem_34_429 Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies
Chen_2019_Alzheimers.Dement.(N.Y)_5_38 The Alzheimer's disease THErapy with NEuroaid (ATHENE) study protocol: Assessing the safety and efficacy of Neuroaid II (MLC901) in patients with mild-to-moderate Alzheimer's disease stable on cholinesterase inhibitors or memantine-A randomized, double-blind, placebo-controlled trial
Chen_2019_Medicine.(Baltimore)_98_e14371 Manifestations of and risk factors for acute myocardial injury after acute organophosphorus pesticide poisoning
de Souza_2019_J.Enzyme.Inhib.Med.Chem_34_631 Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant
Dong_2019_Molecules_24_ Three New 2-(2-Phenylethyl)chromone Derivatives of Agarwood Originated from Gyrinops salicifolia
Jacevic_2019_Sci.Rep_9_1457 Toxic Injury to Muscle Tissue of Rats Following Acute Oximes Exposure
Kaur_2019_Drug.Chem.Toxicol__1 Neuro-protective potential of quercetin during chlorpyrifos induced neurotoxicity in rats
Kucukoglu_2019_Bioorg.Chem_86_316 Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes
Kuzu_2019_Bioorg.Chem_86_187 Mono- or di-substituted imidazole derivatives for inhibition of acetylcholine and butyrylcholine esterases
Li_2019_Molecules_24_489 Isolation of Two New Compounds and Other Constituents from Leaves of Piper crocatum and Study of Their Soluble Epoxide Hydrolase Activities
Mijosek_2019_Sci.Total.Environ_660_1079 Evaluation of multi-biomarker response in fish intestine as an initial indication of anthropogenic impact in the aquatic karst environment
Niwa_2019_Curr.Med.Res.Opin__1 Lifestyle improvement or anti-dementia drugs in Alzheimer's disease: A comment on Kapaki et al. The cognitive effects of cholinesterase inhibitor treatment in every-day practice. Curr Med Res Opin 2005\; 21(6): 871-5
Njoku_2019_Exp.Neurol_315_32 Chronic treatment with galantamine rescues reversal learning in an attentional set-shifting test after experimental brain trauma
Pohanka_2019_Molecules_24_ Biosensors and Bioassays Based on Lipases, Principles and Applications, a Review
Sarasquete_2019_Histol.Histopathol__18090 Effects of the isoflavone daidzein in Senegalese sole, Solea senegalensis: Modulation of the oestrogen receptor-beta, apoptosis and enzymatic signalling pathways
Secci_2019_J.Enzyme.Inhib.Med.Chem_34_597 4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis
Shakil_2019_J.Cell.Biochem__ Molecular interaction of investigational ligands with human brain acetylcholinesterase
Tan_2019_J.Trace.Elem.Med.Biol_52_199 A multifunctional bis-(-)-nor-meptazinol-oxalamide hybrid with metal-chelating property ameliorates Cu(II)-induced spatial learning and memory deficits via preventing neuroinflammation and oxido-nitrosative stress in mice
Vackova_2019_Front.Pharmacol_10_18 Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats
Yang_2019_Parasit.Vectors_12_77 Target-site mutations (AChE-G119S and kdr) in Guangxi Anopheles sinensis populations along the China-Vietnam border
Yang_2019_J.Enzyme.Inhib.Med.Chem_34_651 Synthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer's disease agents
Gumus_2019_Fetal.Pediatr.Pathol__1 A Hemizygous 370 Kilobase Microduplication at Xq13.1 in a Three-Year-Old Boy With Autism and Speech Delay
Guyatt_2019_Hum.Genomics_13_6 A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts
Hashimoto_2019_Front.Pharmacol_10_36 Role of Soluble Epoxide Hydrolase in Metabolism of PUFAs in Psychiatric and Neurological Disorders
Yang_2019_Cancer.Res_79_505 Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk
Abbas_2019_Bioorg.Chem_86_305 The management of diabetes mellitus-imperative role of natural products against dipeptidyl peptidase-4, alpha-glucosidase and sodium-dependent glucose co-transporter 2 (SGLT2)
Abbasi_2019_Pak.J.Pharm.Sci_32_61 Synthesis of some new N-(alkyl\/aralkyl)-N-(2,3-dihydro-1,4-benzodioxan-6-yl)-4-chlorobenzenesulfonamide s as possible therapeutic agents for Alzheimer's disease and Type-2 Diabetes
AlFadly_2019_Eur.J.Med.Chem_167_161 Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
Chen_2019_Pestic.Biochem.Physiol_154_32 Plant allelochemicals affect tolerance of polyphagous lepidopteran pest Helicoverpa armigera (Hubner) against insecticides
Connor_2019_Curr.Opin.Neurobiol_57_71 Pumping the brakes: suppression of synapse development by MDGA-neuroligin interactions
Dong_2019_Sci.Total.Environ_653_1395 Molecular and phenotypic responses of male crucian carp (Carassius auratus) exposed to perfluorooctanoic acid
Dubrovskii_2019_Talanta_197_374 Mass spectrometry based proteomic approach for the screening of butyrylcholinesterase adduct formation with organophosphates
Frolich_2019_Alzheimers.Res.Ther_11_18 Evaluation of the efficacy, safety and tolerability of orally administered BI 409306, a novel phosphodiesterase type 9 inhibitor, in two randomised controlled phase II studies in patients with prodromal and mild Alzheimer's disease
Gombeau_2019_Toxicol.Res_35_25 Protective Effects of Plathymenia reticulata and Connarus favosus Aqueous Extracts against Cadmium- and Mercury-Induced Toxicities
Henriques_2019_Sci.Total.Environ_664_626 Toxicological assessment of anthropogenic Gadolinium in seawater: Biochemical effects in mussels Mytilus galloprovincialis
Jannat_2019_Exp.Mol.Med_51_12 Inhibition of beta-site amyloid precursor protein cleaving enzyme 1 and cholinesterases by pterosins via a specific structure-activity relationship with a strong BBB permeability
Kato_2019_Biosci.Biotechnol.Biochem__1 Bioactive compounds in plant materials for the prevention of diabetesand obesity
Li_2019_Cancer.Manag.Res_11_931 Lipase member H is a downstream molecular target of hypoxia inducible factor-1alpha and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines
Naqvi_2019_Pak.J.Pharm.Sci_32_53 A comparative study showing greater effects of curcumin compared to donepezil on memory function in rats
Nie_2019_PeerJ_7_e6415 The blood parameters and liver function changed inconsistently among children between burns and traumatic injuries
Perovic_2019_Scand.J.Clin.Lab.Invest__1 Influence of hemolysis on clinical chemistry parameters determined with Beckman Coulter tests - detection of clinically significant interference
Serafini_2019_Chemosphere_223_124 Fish exposed to water contaminated with eprinomectin show inhibition of the activities of AChE and Na(+)\/K(+)-ATPase in the brain, and changes in natural behavior
Sereia_2019_PLoS.One_14_e0212089 In vitro evaluation of the protective effects of plant extracts against amyloid-beta peptide-induced toxicity in human neuroblastoma SH-SY5Y cells
Sheynin_2019_Front.Neurosci_13_22 Cholinergic Potentiation Alters Perceptual Eye Dominance Plasticity Induced by a Few Hours of Monocular Patching in Adults
Turkan_2019_Bioorg.Chem_86_420 Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors
Wang_2019_Talanta_197_356 Direct, selective and ultrasensitive electrochemical biosensing of methyl parathion in vegetables using Burkholderia cepacia lipase@MOF nanofibers-based biosensor
Yang_2019_Front.Pharmacol_10_44 Selection of Reference Genes for Expression Analysis in Chinese Medicinal Herb Huperzia serrata
Yao_2019_Molecules_24_ Mori Ramulus (Chin.Ph.)-the Dried Twigs of Morus alba L.\/Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract
Yaribeygi_2019_J.Cell.Biochem__ Natural compounds with DPP-4 inhibitory effects: Implications for the treatment of diabetes
Ayob_2019_BMC.Anesthesiol_19_25 Pre-operative biomarkers and imaging tests as predictors of post-operative delirium in non-cardiac surgical patients: a systematic review
Barranco_2019_Biochem.Med.(Zagreb)_29_010706 Changes of salivary biomarkers under different storage conditions: effects of temperature and length of storage
Bitzinger_2019_Mediators.Inflamm_2019_8274903 In Vivo Effects of Neostigmine and Physostigmine on Neutrophil Functions and Evaluation of Acetylcholinesterase and Butyrylcholinesterase as Inflammatory Markers during Experimental Sepsis in Rats
Blazevic_2019_Molecules_24_ Bunias erucago L.: Glucosinolate Profile and In Vitro Biological Potential
Davenport_2019_Cell.Rep_26_2037 Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition
Ece_2019_J.Biomol.Struct.Dyn__1 Towards More Effective Acetylcholinesterase Inhibitors: A Comprehensive Modelling Study Based On Human Acetylcholinesterase Protein-Drug Complex
Fog_2019_BMC.Geriatr_19_49 Drug use differs by care level. A cross-sectional comparison between older people living at home or in a nursing home in Oslo, Norway
Hauser-Davis_2019_Mar.Pollut.Bull_140_30 Inihibition of mullet (M. liza) brain acetylcholinesterase activity by in vitro polycyclic aromatic hydrocarbon exposure
Jeon_2019_Enzyme.Microb.Technol_124_63 Effect of intense pulsed light on the deactivation of lipase: Enzyme-deactivation kinetics and tertiary structural changes by fragmentation
Junaid_2019_PLoS.One_14_e0211935 Metal based donepezil analogues designed to inhibit human acetylcholinesterase for Alzheimer's disease
Karakaya_2019_Molecules_24_ Molecular Docking Studies of Coumarins Isolated from Extracts and Essential Oils of Zosima absinthifolia Link as Potential Inhibitors for Alzheimer's Disease
Khan_2019_Int.J.Med.Mushrooms_21_181 Bioprospecting of Wild Mushrooms from India with Respect to Their Medicinal Aspects
Lanzarin_2019_Chemosphere_223_514 Dose-dependent effects of a glyphosate commercial formulation - Roundup((R)) UltraMax - on the early zebrafish embryogenesis
Lazarova_2019_J.Pharm.Biomed.Anal_168_174 A comparative study of UHPLC\/Orbitrap MS metabolomics profiles and biological properties of Asphodeline taurica from Bulgaria and Turkey
Lin_2019_J.Neurol.Sci_399_144 Diffuse Lewy body disease
Lopes_2019_Ecotoxicol.Environ.Saf_173_494 Brain acetylcholinesterase of three perciformes: From the characterization to the in vitro effect of metal ions and pesticides
Maroyi_2019_Molecules_24_ Review of Ethnomedicinal, Phytochemical and Pharmacological Properties of Lannea schweinfurthii (Engl.) Engl
Meng_2019_Exp.Ther.Med_17_1611 Cholinesterase inhibitors and memantine for Parkinson's disease dementia and Lewy body dementia: A meta-analysis
Missaglia_2019_Cells_8_ Neutral Lipid Storage Diseases as Cellular Model to Study Lipid Droplet Function
Mitra_2019_Front.Neurosci_13_38 Innovative Therapy for Alzheimer's Disease-With Focus on Biodelivery of NGF
Mohammadzadeh_2019_Nutr.Neurosci__1 Crocin-protected malathion-induced spatial memory deficits by inhibiting TAU protein hyperphosphorylation and antiapoptotic effects
Mullane_2019_Curr.Protoc.Pharmacol__e57 Preclinical Models of Alzheimer's Disease: Relevance and Translational Validity
Pereira_2019_Ecotoxicol.Environ.Saf_173_482 Cholinesterases characterization of three tropical fish species, and their sensitivity towards specific contaminants
Postu_2019_Biomed.Pharmacother_112_108673 Pinus halepensis essential oil attenuates the toxic Alzheimer's amyloid beta (1-42)-induced memory impairment and oxidative stress in the rat hippocampus
Ragab_2019_Bioorg.Chem_86_557 Chlorinated tacrine analogs: Design, synthesis and biological evaluation of their anti-cholinesterase activity as potential treatment for Alzheimer's disease
Reetz_2019_Acc.Chem.Res_52_336 Directed Evolution of Artificial Metalloenzymes: A Universal Means to Tune the Selectivity of Transition Metal Catalysts?
Saleh_2019_Bratisl.Lek.Listy_120_148 Investigation of THDOC effects on pathophysiological signs of Alzheimer's disease as an endogenous neurosteroid: inhibition of acetylcholinesterase and plaque deposition
Sharma_2019_Eur.J.Med.Chem_167_510 Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease
Sun_2019_Mar.Drugs_17_ 9-Methylfascaplysin Is a More Potent Abeta Aggregation Inhibitor than the Marine-Derived Alkaloid, Fascaplysin, and Produces Nanomolar Neuroprotective Effects in SH-SY5Y Cells
Taslimi_2019_J.Biochem.Mol.Toxicol__e22313 The antidiabetic and anticholinergic effects of chrysin on cyclophosphamide-induced multiple organ toxicity in rats: Pharmacological evaluation of some metabolic enzyme activities
Tomita_2019_Curr.Opin.Neurobiol_57_81 Molecular constituents and localization of the ionotropic GABA receptor complex in vivo
Ullas_2019_Rep.Biochem.Mol.Biol_7_174 Increased Levels of Acetylcholinesterase, Paraoxonase 1, and Copper in Patients with Moderate Depression- a Preliminary Study
Verheyen_2019_Environ.Pollut_248_209 Current and future daily temperature fluctuations make a pesticide more toxic: Contrasting effects on life history and physiology
Wang_2019_Drug.Des.Devel.Ther_13_501 Neuroprotective potential of ketamine prevents developing brain structure impairment and alteration of neurocognitive function induced via isoflurane through the PI3K\/AKT\/GSK-3beta pathway
Wei_2019_Bull.Entomol.Res__1 Latrophilin mediates insecticides susceptibility and fecundity through two carboxylesterases, esterase4 and esterase6, in Tribolium castaneum
Xue_2019_Sci.Rep_9_2558 The clinical parameters for the diagnosis of hepatitis B virus related acute-on-chronic liver failure with sepsis
Acar_2019_Molecules_24_ Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives
de Oliveira_2019_Sci.Total.Environ_667_371 Toxicological effects of anthropogenic activities in Geophagus brasiliensis from a coastal river of southern Brazil: A biomarker approach
Farzi_2019_Ann.Neurosci_25_121 Exercise Improves Recognition Memory and Acetylcholinesterase Activity in the Beta Amyloid-Induced Rat Model of Alzheimer's Disease
Gagnaire_2019_Ecotoxicol.Environ.Saf_174_153 Physiological effects of gamma irradiation in the honeybee, Apis mellifera
Koksal_2019_J.Biochem.Mol.Toxicol__e22300 Investigation of the effects of some sulfonamides on acetylcholinesterase and carbonic anhydrase enzymes
Kong_2019_Cell.Rep_26_2451 The Galleria mellonella Hologenome Supports Microbiota-Independent Metabolism of Long-Chain Hydrocarbon Beeswax
Lee_2019_Plant.Sci_279_51 Lipases associated with plant defense against pathogens
Mazumder_2019_Sci.Rep_9_3097 Neurological sequel of chronic kidney disease: From diminished Acetylcholinesterase activity to mitochondrial dysfunctions, oxidative stress and inflammation in mice brain
San-Juan-Rodriguez_2019_JAMA.Netw.Open_2_e190213 Association of Antidementia Therapies With Time to Skilled Nursing Facility Admission and Cardiovascular Events Among Elderly Adults With Alzheimer Disease
Serrano-Medina_2019_Int.J.Environ.Res.Public.Health_16_ Neuropsychiatric Disorders in Farmers Associated with Organophosphorus Pesticide Exposure in a Rural Village of Northwest Mexico
Son_2019_Int.J.Mol.Sci_20_ Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer's Disease
Takegawa_2019_J.Crit.Care_51_139 Serum albumin as a risk factor for death in patients with prolonged sepsis: An observational study
Tvarijonaviciute_2019_Vet.J_244_51 Identification of changes in serum analytes and possible metabolic pathways associated with canine obesity-related metabolic dysfunction
Ujan_2019_Molecules_24_ Drug-1,3,4-Thiadiazole Conjugates as Novel Mixed-Type Inhibitors of Acetylcholinesterase: Synthesis, Molecular Docking, Pharmacokinetics, and ADMET Evaluation
Wang_2019_Eur.J.Med.Chem_168_207 Design, synthesis, and evaluation of isoflavone analogs as multifunctional agents for the treatment of Alzheimer's disease
Zhang_2019_Bioelectrochemistry_127_163 A sensitive amperometric AChE-biosensor for organophosphate pesticides detection based on conjugated polymer and Ag-rGO-NH2 nanocomposite
Zhu_2019_Eur.J.Med.Chem_168_330 Inhibiting Abeta toxicity in Alzheimer's disease by a pyridine amine derivative
Ademosun_2019_Biomed.Pharmacother_111_1029 Anogeissus leiocarpus attenuates paroxetine-induced erectile dysfunction in male rats via enhanced sexual behavior, nitric oxide level and antioxidant status
Agatonovic-Kustrin_2019_Mar.Drugs_17_ High-Performance Thin-Layer Chromatography Hyphenated with Microchemical and Biochemical Derivatizations in Bioactivity Profiling of Marine Species
Barmak_2019_Microb.Pathog_130_95 Antibacterial studies of hydroxyspiro[indoline-3,9-xanthene]trione against spiro[indoline3,9-xanthene]trione and their use as acetyl and butyrylcholinesterase inhibitors
Borase_2019_Environ.Toxicol.Pharmacol_68_4 Nano-eco toxicity study of gold nanoparticles on aquatic organism Moina macrocopa: As new versatile ecotoxicity testing model
Chen_2019_Foods_8_ Preventive Effects of Different Fermentation Times of Shuidouchi on Diphenoxylate-Induced Constipation in Mice
Gul_2019_J.Chin.Med.Assoc_82_40 Huperzine-A response to cognitive impairment and task switching deficits in patients with Alzheimer's disease
Hackenberger_2019_Chemosphere_224_572 Effects of single and combined exposure to nano and bulk zinc-oxide and propiconazole on Enchytraeus albidus
Hinojosa_2019_Sci.Total.Environ_668_547 Neurotoxicity induced by microcystins and cylindrospermopsin: A review
Hinojosa_2019_Chemosphere_224_751 Neurotoxic assessment of Microcystin-LR, cylindrospermopsin and their combination on the human neuroblastoma SH-SY5Y cell line
Kim_2019_Molecules_24_ Laxative Effect of Spicatoside A by Cholinergic Regulation of Enteric Nerve in Loperamide-Induced Constipation: ICR Mice Model
Kurimoto_2019_PLoS.One_14_e0207969 TAK-071, a muscarinic M1 receptor positive allosteric modulator, attenuates scopolamine-induced quantitative electroencephalogram power spectral changes in cynomolgus monkeys
Kwok_2019_World.J.Gastrointest.Surg_11_101 Acquired segmental colonic hypoganglionosis in an adult Caucasian male: A case report
Miranda_2019_Biomed.Pharmacother_111_1383 Chemical constituents of Cochlospermum regium (Schrank) Pilg. root and its antioxidant, antidiabetic, antiglycation, and anticholinesterase effects in Wistar rats
Ozil_2019_Bioorg.Chem_86_705 Synthesis of 5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-one's aryl Schiff base derivatives and investigation of carbonic anhydrase and cholinesterase (AChE, BuChE) inhibitory properties
Paul_2019_Sci.Total.Environ_668_104 Effect of temperature on triclosan toxicity in Pangasianodon hypophthalmus (Sauvage, 1878): Hematology, biochemistry and genotoxicity evaluation
Pavela_2019_Molecules_24_ Exploring the Insecticidal Potential of Boldo (Peumus boldus) Essential Oil: Toxicity to Pests and Vectors and Non-target Impact on the Microcrustacean Daphnia magna
Sanchez-Hernandez_2019_Sci.Total.Environ_667_761 Biochar increases pesticide-detoxifying carboxylesterases along earthworm burrows
Silva_2019_PLoS.One_14_e0213393 Chemical profile of Lippia thymoides, evaluation of the acetylcholinesterase inhibitory activity of its essential oil, and molecular docking and molecular dynamics simulations
Vallejo_2019_Nat.Prod.Res__1 12alpha-hydroxy-N-demethyl-sauroxine, a lycodane type alkaloid from Phlegmariurus saururus
Wang_2019_J.Enzyme.Inhib.Med.Chem_34_753 Inhibition potential of phenolic constituents from the aerial parts of Tetrastigma hemsleyanum against soluble epoxide hydrolase and nitric oxide synthase
Xu_2019_Biosens.Bioelectron_131_232 A ratiometric fluorescence probe based on carbon dots for discriminative and highly sensitive detection of acetylcholinesterase and butyrylcholinesterase in human whole blood
Yang_2019_Sci.Total.Environ_667_435 Antioxidant defence system is responsible for the toxicological interactions of mixtures: A case study on PFOS and PFOA in Daphnia magna
Zengin_2019_J.Biomol.Struct.Dyn__1 Synthesis, Anticholinesterase Activity and Molecular Modeling Studies of Novel Carvacrol Substituted Amide Derivatives
Arvaniti_2019_Food.Res.Int_119_244 Review on fresh and dried figs: Chemical analysis and occurrence of phytochemical compounds, antioxidant capacity and health effects
Cao_2019_Aquat.Toxicol_210_167 Seawater acidification increases copper toxicity: A multi-biomarker approach with a key marine invertebrate, the Pacific Oyster Crassostrea gigas
Cao_2019_Carbohydr.Polym_213_304 Preparation, characterization and application of rod-like chitin nanocrystal by using p-toluenesulfonic acid\/choline chloride deep eutectic solvent as a hydrolytic media
Correia_2019_Environ.Toxicol.Pharmacol_68_27 Effects of the chronic exposure to cerium dioxide nanoparticles in Oncorhynchus mykiss: Assessment of oxidative stress, neurotoxicity and histological alterations
Deng_2019_J.Ethnopharmacol_236_288 In vivo and in vitro metabolism and pharmacokinetics of cholinesterase inhibitor deoxyvasicine from aerial parts of Peganum harmala Linn in rats via UPLC-ESI-QTOF-MS and UPLC-ESI-MS\/MS
Leris_2019_Ecotoxicol.Environ.Saf_175_48 Acute and sub-chronic toxicity bioassays of Olive Mill Wastewater on the Eastern mosquitofish Gambusia holbrooki
Loesche_2019_Molecules_24_ Triterpene-Based Carboxamides Act as Good Inhibitors of Butyrylcholinesterase
Malegiannaki_2019_Hell.J.Nucl.Med_22 Suppl_123 Ageing and Down syndrome: Neurocognitive characteristics and pharmacological treatment
Munder_2019_Medchemcomm_10_280 Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic beta-cells' proliferation and functions
Nishitsuji_2019_Sci.Rep_9_4607 Draft genome of the brown alga, Nemacystus decipiens, Onna-1 strain: Fusion of genes involved in the sulfated fucan biosynthesis pathway
Oztaskin_2019_Bioorg.Chem_87_91 Synthesis and characterization of novel bromophenols: Determination of their anticholinergic, antidiabetic and antioxidant activities
Peric_2019_Chemosphere_225_126 The effect of copper and chlorpyrifos co-exposure on biomarkers in the marine mussel Mytilus galloprovincialis
Shams-Alizadeh_2019_Clin.Neuropharmacol_42_27 Effect of Donepezil on Cognitive Deficits Associated With Electroconvulsive Therapy: A Randomized Triple-blind Clinical Trial
Shang_2019_Vet.Parasitol_267_54 Acaricidal activity and enzyme inhibitory activity of active compounds of essential oils against Psoroptes cuniculi
Takahashi_2019_Eur.J.Pharm.Sci_132_125 Synthesis and evaluation of haloperidol ester prodrugs metabolically activated by human carboxylesterase
Uchibori-Asano_2019_Sci.Rep_9_4203 Genome-wide Identification of Tebufenozide Resistant Genes in the smaller tea tortrix, Adoxophyes honmai (Lepidoptera: Tortricidae)
Wu_2019_Bioresour.Technol_282_390 Rhodopseudomonas palustris wastewater treatment: Cyhalofop-butyl removal, biochemicals production and mathematical model establishment
Wu_2019_Talanta_198_8 Fluorescence sensor for facile and visual detection of organophosphorus pesticides using AIE fluorogens-SiO2-MnO2 sandwich nanocomposites
Alvarado_2019_J.Biomol.Struct.Dyn__1 Understanding the Enzyme-Ligand Complex: Insights from All-Atom Simulations of Butyrylcholinesterase Inhibition
Asmat_2019_Mater.Sci.Eng.C.Mater.Biol.Appl_99_25 A robust nanobiocatalyst based on high performance lipase immobilized to novel synthesised poly(o-toluidine) functionalized magnetic nanocomposite: Sterling stability and application
Dumitru_2019_Phytomedicine_58_152889 Agathisflavone isolated from Schinus polygamus (Cav.) Cabrera leaves prevents scopolamine-induced memory impairment and brain oxidative stress in zebrafish (Danio rerio)
Falfushynska_2019_Saudi.J.Biol.Sci_26_481 A calcium channel blocker nifedipine distorts the effects of nano-zinc oxide on metal metabolism in the marsh frog Pelophylax ridibundus
Jacobs_2019_Front.Neurol_10_167 Non-invasive Cognitive Enhancement in Epilepsy
Lee_2019_Biosci.Biotechnol.Biochem__1 Ingestion of difructose anhydride III partially suppresses the deconjugation and 7alpha-dehydroxylation of bile acids in rats fed with a cholic acid-supplemented diet
Ma_2019_J.Agric.Food.Chem_67_2429 Developmental Toxicity of a Neonicotinoid Insecticide, Acetamiprid to Zebrafish Embryos
Mazumder_2019_Med.Hypotheses_125_94 Tea polyphenols as multi-target therapeutics for Alzheimer's disease: An in silico study
McShane_2019_Cochrane.Database.Syst.Rev_3_CD003154 Memantine for dementia
Nkpaa_2019_J.Trace.Elem.Med.Biol_53_8 Rutin abrogates manganese-Induced striatal and hippocampal toxicity via inhibition of iron depletion, oxidative stress, inflammation and suppressing the NF-kappaB signaling pathway
Ojo_2019_BMC.Complement.Altern.Med_19_71 Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats
Pan_2019_Molecules_24_ Royal Jelly Ameliorates Behavioral Deficits, Cholinergic System Deficiency, and Autonomic Nervous Dysfunction in Ovariectomized Cholesterol-Fed Rabbits
Sani_2019_J.Adv.Res_16_87 A standardised Andrographis paniculata Burm. Nees aqueous extract prevents Lipopolysaccharide-induced cognitive deficits through suppression of inflammatory cytokines and oxidative stress mediators
Santana_2019_Bioorg.Chem_87_169 Evaluation of guanylhydrazone derivatives as inhibitors of Candida rugosa digestive lipase: Biological, biophysical, theoretical studies and biotechnological application
Shen_2019_Carbohydr.Res_476_53 Mass spectrometry-based identification of carbohydrate anomeric configuration to determine the mechanism of glycoside hydrolases
Sut_2019_Molecules_24_ Triterpene Acid and Phenolics from Ancient Apples of Friuli Venezia Giulia as Nutraceutical Ingredients: LC-MS Study and In Vitro Activities
Tang_2019_Anal.Chim.Acta_1060_97 Thiocholine-triggered reaction in personal glucose meters for portable quantitative detection of organophosphorus pesticide
Zhang_2019_Oxid.Med.Cell.Longev_2019_8636835 Studies of the Anti-amnesic Effects and Mechanisms of Single and Combined Use of Donepezil and Ginkgo Ketoester Tablet on Scopolamine-Induced Memory Impairment in Mice
Zhang_2019_Evid.Based.Complement.Alternat.Med_2019_2721413 A Review of Danshen Combined with Clopidogrel in the Treatment of Coronary Heart Disease
Atri_2019_Semin.Neurol_39_227 Current and Future Treatments in Alzheimer's Disease
Bak_2019_Int.J.Mol.Sci_20_1524 Novel Benzene-Based Carbamates for AChE\/BChE Inhibition: Synthesis and Ligand\/Structure-Oriented SAR Study
Chiroma_2019_Toxics_7_ Protective Effects of Centella asiatica on Cognitive Deficits Induced by D-gal\/AlCl(3) via Inhibition of Oxidative Stress and Attenuation of Acetylcholinesterase Level
Delnat_2019_Aquat.Toxicol_211_38 Whether warming magnifies the toxicity of a pesticide is strongly dependent on the concentration and the null model
Dong_2019_Drug.Deliv_26_416 Application and design of esterase-responsive nanoparticles for cancer therapy
Erukainure_2019_Food.Chem.Toxicol_127_206 Hyperglycemia-induced oxidative brain injury: Therapeutic effects of Cola nitida infusion against redox imbalance, cerebellar neuronal insults, and upregulated Nrf2 expression in type 2 diabetic rats
Iturbe-Requena_2019_Ecotoxicol.Environ.Saf_176_219 Toxic effects of new ethyl-carbamates on the morphology, mortality and acetylcholinesterase activity of Eisenia foetida
Jasiecki_2019_Sci.Rep_9_5223 Synergy between the alteration in the N-terminal region of butyrylcholinesterase K variant and apolipoprotein E4 in late-onset Alzheimer's disease
Mollazadeh_2019_Bioorg.Chem_87_506 New benzyl pyridinium derivatives bearing 2,4-dioxochroman moiety as potent agents for treatment of Alzheimer's disease: Design, synthesis, biological evaluation, and docking study
Morais_2019_Ecotoxicol.Environ.Saf_176_196 Biological, biochemical and genotoxic effects of Sb in the midge Chironomus sancticaroli Strixino and Strixino, 1981 (Diptera: Chironomidae)
Saleem_2019_J.Pharm.Biomed.Anal_170_132 Multidirectional insights into the biochemical and toxicological properties of Bougainvillea glabra (Choisy.) aerial parts: A functional approach for bioactive compounds
Sezgin_2019_Semin.Neurol_39_274 Parkinson's Disease Dementia and Lewy Body Disease
Spinelli_2019_Nat.Prod.Res__1 Amphibian skin extracts as source of bioactive multi-target agents against different pathways of Alzheimer's disease
Tahir_2019_J.Insect.Sci_19_ Effect of Pesticides on Biological Control Potential of Neoscona theisi (Araneae: Araneidae)
Trueblood_2019_J.Prim.Care.Community.Health_10_2150132719838716 Feasibility of Portable Fingerstick Cholinesterase Testing in Adolescents in South Texas
Turkiewicz_2019_Molecules_24_ Antidiabetic, Anticholinesterase and Antioxidant Activity vs. Terpenoids and Phenolic Compounds in Selected New Cultivars and Hybrids of Artichoke Cynara scolymus L
Wu_2019_Small__e1900632 Polydopamine-Capped Bimetallic AuPt Hydrogels Enable Robust Biosensor for Organophosphorus Pesticide Detection
Xie_2019_Chem.Pharm.Bull.(Tokyo)_67_345 Design, Synthesis and Insecticide Activity of Novel Acetylcholinesterase Inhibitors: Triazolinone and Phthalimide Heterodimers
Xiong_2019_Phytochemistry_162_183 Lycofargesiines A-F, further Lycopodium alkaloids from the club moss Huperzia fargesii
Zengin_2019_Food.Chem.Toxicol_127_237 Multidirectional biological investigation and phytochemical profile of Rubus sanctus and Rubus ibericus
Zhang_2019_Bioorg.Chem_87_395 Design, synthesis and evaluation of chalcone Mannich base derivatives as multifunctional agents for the potential treatment of Alzheimer's disease
Zhou_2019_J.Colloid.Interface.Sci_546_211 Surface functionalization of graphene oxide by amino acids for Thermomyces lanuginosus lipase adsorption
Zhu_2019_Fitoterapia_134_474 Lycocasuarines I-Q, new Lycopodium alkaloids isolated from Lycopodiastrum casuarinoides
Bagheri_2019_Biosens.Bioelectron_134_97 A 96-well wax printed Prussian Blue paper for the visual determination of cholinesterase activity in human serum
Bang_2019_J.Vet.Sci_20_e9 Acetylcholinesterase activity in the brain of wild birds in Korea-2014 to 2016
Bernieri_2019_Drug.Chem.Toxicol__1 Effect of pesticide exposure on total antioxidant capacity and biochemical parameters in Brazilian soybean farmers
Brun_2019_Sci.Rep_9_5583 3D Synthetic Peptide-based Architectures for the Engineering of the Enteric Nervous System
Bruno_2019_Nat.Prod.Res__1 Composition and biological activities of the essential oil from a Sicilian accession of Prangos ferulacea (L.) Lindl
Canli_2019_Environ.Toxicol.Pharmacol_69_72 Responses of biomarkers belonging to different metabolic systems of rats following oral administration of aluminium nanoparticle
Cocci_2019_Aquat.Toxicol_209_81 Changes in expression of microRNA potentially targeting key regulators of lipid metabolism in primary gilthead sea bream hepatocytes exposed to phthalates or flame retardants
Cortez_2019_Mar.Pollut.Bull_141_366 Marine contamination and cytogenotoxic effects of fluoxetine in the tropical brown mussel Perna perna
Gupta_2019_3.Biotech_9_107 A hydrolase with esterase activity expressed from a fosmid gene bank prepared from DNA of a North West Himalayan glacier frozen soil sample
Haque_2019_PLoS.One_14_e0214236 Chlorothalonil induces oxidative stress and reduces enzymatic activities of Na+\/K+-ATPase and acetylcholinesterase in gill tissues of marine bivalves
Khazdair_2019_J.Tradit.Complement.Med_9_98 Neuroprotective potency of some spice herbs, a literature review
Magalhaes_2019_Rev.Bras.Enferm_72_32 Occupational exposure and poisoning by chemical products in the Federal District
Marta_2019_Cesk.Patol_55_53 Immunohistochemical diagnostics of Hirschprungs disease using calretinin
Mathew_2019_Artif.Cells.Nanomed.Biotechnol_47_1149 Design, synthesis and characterization of enzyme-analogue-built polymer catalysts as artificial hydrolases
Wang_2019_Bioorg.Chem_87_720 Design, synthesis and evaluation of a novel metal chelator as multifunctional agents for the treatment of Alzheimer's disease
Yin_2019_Evid.Based.Complement.Alternat.Med_2019_2394605 Pharmacological Effects of Verticine: Current Status
Yu_2019_Front.Pharmacol_10_268 Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin
Zhang_2019_Chemosphere_226_817 Bioaccumulation, behavior changes and physiological disruptions with gender-dependent in lizards (Eremias argus) after exposure to glufosinate-ammonium and l-glufosinate-ammonium
Zhu_2019_Front.Pharmacol_10_258 Jia-Wei-Kai-Xin-San, an Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of Abeta1-42 Induced Cognitive Deficit Mice
Zurita_2019_Ecotoxicol.Environ.Saf_176_309 Integration of fish cell cultures in the toxicological assessment of effluents
Araujo_2019_Front.Neuroanat_13_36 Cyto- and Myelo-Architecture of the Amygdaloid Complex of the Common Marmoset Monkey (Callithrix jacchus)
Baakman_2019_Alzheimers.Dement.(N.Y)_5_89 No synergistic effect of subtherapeutic doses of donepezil and EVP-6124 in healthy elderly subjects in a scopolamine challenge model
Barbosa_2019_Biotechnol.Prog__e2816 Effects of phosphonium-based ionic liquids on the lipase activity evaluated by experimental results and molecular docking
Chiu_2019_J.Biol.Chem_294_2949 Allosteric disulfides: Sophisticated molecular structures enabling flexible protein regulation
Fereidouni_2019_J.Biochem.Mol.Toxicol__e22341 Quercetin plays protective role in oxidative induced apoptotic events during chronic chlorpyrifos exposure to rats
Ji_2019_Exp.Ther.Med_17_3755 Protective role of phenylethanoid glycosides, Torenoside B and Savatiside A, in Alzheimer's disease
Kohelova_2019_Molecules_24_ Derivatives of the beta-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease
Oyeleye_2019_Andrologia__e13281 Effect of p-coumaric acid on the erectogenic enzyme activities and non-protein thiol level in the penile tissue of normal and doxorubicin-induced oxidative stress male rat
Paula_2019_Molecules_24_ Enzyme Inhibitory Potential of Ligustrum lucidum Aiton Berries
Poirier_2019_Chem.Biol.Interact_13ChEPon_306_96 Evaluation of a robust engineered enzyme towards organophosphorus insecticide bioremediation using planarians as biosensors
Sakers_2019_Curr.Opin.Neurobiol_57_163 Control of neural development and function by glial neuroligins
Schmitt_2019_Neurotoxicol.Teratol_73_67 Comparative analyses of the neurobehavioral, molecular, and enzymatic effects of organophosphates on embryo-larval zebrafish (Danio rerio)
Shawky_2019_Nat.Prod.Res__1 Profiling of acetylcholinesterase inhibitory alkaloids from some Crinum, Habranthus and Zephyranthes species by GC-MS combined with multivariate analyses and in silico studies
Soler_2019_BMC.Geriatr_19_101 Continuation versus discontinuation of treatment for severe dementia: randomized, pragmatic, open-label, clinical trial to evaluate the efficacy of continuing drug treatment in patients with severe dementia (STOP-DEM)
Tiwari_2019_Toxicol.Rep_6_288 Assessment of acute toxicity and biochemical responses to chlorpyrifos, cypermethrin and their combination exposed earthworm, Eudrilus eugeniae
Turkan_2019_J.Biochem.Mol.Toxicol__e22340 Tannic acid as a natural antioxidant compound: Discovery of a potent metabolic enzyme inhibitor for a new therapeutic approach in diabetes and Alzheimer's disease
Wan_2019_FASEB.J__fj201802675R Exosomes from activated hepatic stellate cells contain GLUT1 and PKM2: a role for exosomes in metabolic switch of liver nonparenchymal cells
Abolhassani_2019_Ecotoxicol.Environ.Saf_178_168 Organochlorine and organophosphorous pesticides may induce colorectal cancer\; A case-control study
Ashmawy_2019_Molecules_24_ Novel Carbon\/PEDOT\/PSS-Based Screen-Printed Biosensors for Acetylcholine Neurotransmitter and Acetylcholinesterase Detection in Human Serum
Cilerdzic_2019_Int.J.Med.Mushrooms_21_275 Pleurotus ostreatus and Laetiporus sulphureus (Agaricomycetes): Possible Agents against Alzheimer and Parkinson Diseases
Damodaran_2019_Pharmacol.Rep_71_443 Chronic cerebral hypoperfusion-induced memory impairment and hippocampal long-term potentiation deficits are improved by cholinergic stimulation in rats
da Costa_2019_Pharmaceuticals.(Basel)_12_ Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos
Genc Bilgicli_2019_Bioorg.Chem_88_102931 Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials
Geronikaki_2019_Curr.Top.Med.Chem_19_244 Trends in Enzyme Inhibition and Activation in Drug Design - Part-I
Habtemariam_2019_Molecules_24_ Natural Products in Alzheimer's Disease Therapy: Would Old Therapeutic Approaches Fix the Broken Promise of Modern Medicines?
Houze_2019_Toxics_7_ Comparison of the Respiratory Toxicity and Total Cholinesterase Activities in Dimethyl Versus Diethyl Paraoxon-Poisoned Rats
Kim_2019_Int.J.Mol.Sci_20_ Green Tea Seed Oil Suppressed Abeta1(-)42-Induced Behavioral and Cognitive Deficit via the Abeta-Related Akt Pathway
Kopjar_2019_Molecules_24_ DNA Damaging Effects, Oxidative Stress Responses and Cholinesterase Activity in Blood and Brain of Wistar Rats Exposed to Delta(9)-Tetrahydrocannabinol
Le Navenant_2019_Chemosphere_227_416 Metabolic mechanisms and acetylcholinesterase sensitivity involved in tolerance to chlorpyrifos-ethyl in the earwig Forficula auricularia
Lelario_2019_Toxins.(Basel)_11_ A Complete Survey of Glycoalkaloids Using LC-FTICR-MS and IRMPD in a Commercial Variety and a Local Landrace of Eggplant (Solanum melongena L.) and their Anticholinesterase and Antioxidant Activities
Logroscino_2019_Expert.Opin.Pharmacother__1 Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs
Makhaeva_2019_Dokl.Biochem.Biophys_484_1 Anticholinesterase and Antioxidant Activity of New Binary Conjugates of gamma-Carbolines
Ramos_2019_Molecules_24_ QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy
Rotundo_2019_Sci.Rep_9_6429 Biological activity of Dittrichia viscosa (L.) Greuter extracts against adult Sitophilus granarius (L.) (Coleoptera, Curculionidae) and identification of active compounds
Schimidt_2019_Physiol.Behav_206_206 Strength training and running elicit different neuroprotective outcomes in a beta-amyloid peptide-mediated Alzheimer's disease model
Sumirtanurdin_2019_Clin.Interv.Aging_14_631 Effect of genetic polymorphisms on Alzheimer's disease treatment outcomes: an update
Westfall_2019_PLoS.One_14_e0214985 A novel synbiotic delays Alzheimer's disease onset via combinatorial gut-brain-axis signaling in Drosophila melanogaster
Zorbaz_2019_Chem.Biol.Interact_13ChEPon_307_16 Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes
Abdelgaleil_2019_Pestic.Biochem.Physiol_156_105 Acaricidal activity, biochemical effects and molecular docking of some monoterpenes against two-spotted spider mite (Tetranychus urticae Koch)
Araujo_2019_Ecotoxicol.Environ.Saf_178_230 Toxicity of lead and mancozeb differs in two monophyletic Daphnia species
Dash_2019_Bioorg.Chem_88_102947 Isolation, identification, and quantification of Pentylcurcumene from Geophila repens: A new class of cholinesterase inhibitor for Alzheimer's disease
de Oliveira_2019_Ecotoxicol.Environ.Saf_179_135 Investigation of pesticide exposure by genotoxicological, biochemical, genetic polymorphic and in silico analysis
Eskandari-Roozbahani_2019_Basic.Clin.Neurosci_10_85 Neuroprotective Effect of Zataria Multiflora Essential Oil on Rats With Alzheimer Disease: A Mechanistic Study
Eskandary_2019_Basic.Clin.Neurosci_10_109 Effects of Donepezil Hydrochloride on Neuronal Response of Pyramidal Neurons of the CA1 Hippocampus in Rat Model of Alzheimer's Disease
Farizatto_2019_Sci.Rep_9_6532 Early Synaptic Alterations and Selective Adhesion Signaling in Hippocampal Dendritic Zones Following Organophosphate Exposure
Jeyakumar_2019_Bioorg.Chem_88_102935 alpha-bisabolol beta-D-fucopyranoside as a potential modulator of beta-amyloid peptide induced neurotoxicity: An in vitro &in silico study
Liu_2019_Chem.Biol.Interact_13ChEPon_306_147 Activation of G protein-coupled receptor 30 by flavonoids leads to expression of acetylcholinesterase in cultured PC12cells
Mao_2019_Pestic.Biochem.Physiol_156_80 The influence of temperature on the toxicity of insecticides to Nilaparvata lugens (Stal)
Oliveira_2019_Eur.J.Med.Chem_174_116 Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents
Pinder_2019_J.Crit.Care_52_126 Effect of physostigmine on recovery from septic shock following intra-abdominal infection - Results from a randomized, double-blind, placebo-controlled, monocentric pilot trial (Anticholium(R) per Se)
Pourshojaei_2019_Comput.Biol.Chem_80_249 Synthesis, biological evaluation, and computational studies of novel fused six-membered O-containing heterocycles as potential acetylcholinesterase inhibitors
Qiao_2019_Adipocyte_8_190 Adipocyte abundances of CES1, CRYAB, ENO1 and GANAB are modified in-vitro by glucose restriction and are associated with cellular remodelling during weight regain
Rajkumar_2019_Pestic.Biochem.Physiol_156_138 Toxicity, antifeedant and biochemical efficacy of Mentha piperita L. essential oil and their major constituents against stored grain pest
Sepcic_2019_PLoS.One_14_e0216077 First evidence of cholinesterase-like activity in Basidiomycota
Varo_2019_Sci.Total.Environ_675_570 Time-dependent effects of polystyrene nanoparticles in brine shrimp Artemia franciscana at physiological, biochemical and molecular levels
Wu_2019_Nutrients_11_ Hepatoprotective Potential of Partially Hydrolyzed Guar Gum against Acute Alcohol-Induced Liver Injury in Vitro and Vivo
Zhu_2019_Sci.Total.Environ_668_1117 Variation in metabolism and degradation of di-n-butyl phthalate (DBP) by high- and low-DBP accumulating cultivars of rice (Oryza sativa L.) and crude enzyme extracts
Abdel-Wahab_2019_Drug.Des.Devel.Ther_13_1155 Neuroprotective effect of N-acetylcysteine against cisplatin-induced toxicity in rat brain by modulation of oxidative stress and inflammation
Abu-Taweel_2019_Saudi.J.Biol.Sci_26_736 Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring
Connelly_2019_BMC.Neurol_19_88 Peripheral vascular responses to acetylcholine as a predictive tool for response to cholinesterase inhibitors in Alzheimer's disease
Gilhus_2019_Nat.Rev.Dis.Primers_5_30 Myasthenia gravis
Hu_2019_Biosens.Bioelectron_136_112 Visual detection of mixed organophosphorous pesticide using QD-AChE aerogel based microfluidic arrays sensor
Imai_2019_Yakugaku.Zasshi_139_837 [Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]
Kim_2019_Evid.Based.Complement.Alternat.Med_2019_5160293 WS-5 Extract of Curcuma longa, Chaenomeles sinensis, and Zingiber officinale Contains Anti-AChE Compounds and Improves beta-Amyloid-Induced Memory Impairment in Mice
Kim_2019_BMC.Complement.Altern.Med_19_94 Leaf extracts from Dendropanax morbifera Leveille mitigate mercury-induced reduction of spatial memory, as well as cell proliferation, and neuroblast differentiation in rat dentate gyrus
Luo_2019_Front.Pharmacol_10_395 Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway
Saffari_2019_Orphanet.J.Rare.Dis_14_96 Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age - a multicenter retrospective study
Saouessi_2019_J.Chem.Phys_150_161104 Asymptotic analysis of quasielastic neutron scattering data from human acetylcholinesterase reveals subtle dynamical changes upon ligand binding
Seto_2019_Yakugaku.Zasshi_139_715 [Analysis of Countermeasures against Chemical Terrorism]
Singh_2019_J.Biomol.Struct.Dyn__1 Inhibition of Alzheimer's amyloid-beta42 peptide aggregation by a bi-functional bis-tryptoline triazole: Key insights from molecular dynamics simulations
Tarakemeh_2019_J.Pharm.Biomed.Anal_172_230 Screening of Amaryllidaceae alkaloids in bulbs and tissue cultures of Narcissus papyraceus and four varieties of N. tazetta
Trenaman_2019_SAGE.Open.Med_7_2050312119845715 Sex and gender differences in polypharmacy in persons with dementia: A scoping review
Umar_2019_Eur.J.Med.Chem_175_2 A multifunctional therapeutic approach: Synthesis, biological evaluation, crystal structure and molecular docking of diversified 1H-pyrazolo[3,4-b]pyridine derivatives against Alzheimer's disease
Wu_2019_Bioorg.Chem_88_102949 Highly selective carbamate-based butyrylcholinesterase inhibitors derived from a naturally occurring pyranoisoflavone
Zhu_2019_Int.J.Mol.Sci_20_ Predicting the Toxicity of Ionic Liquids toward Acetylcholinesterase Enzymes Using Novel QSAR Models
Contreras-Aguilar_2019_Res.Vet.Sci_124_383 Biochemical changes in saliva of cows with inflammation: A pilot study
Duflot_2019_Cardiovasc.Diabetol_18_35 Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients
Gobel_2019_Front.Pharmacol_10_263 Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor gamma
Huang_2019_Bioengineered_10_150 Different construction strategies affected on the physiology of Pichia pastoris strains highly expressed lipase by transcriptional analysis of key genes
Ibitoye_2019_J.Diet.Suppl__1 Protective Influence of Phyllanthus Muellarianus on Ciprofloxacin-Induced Neurotoxicity in Male Rats
Jasiecki_2019_Chem.Biol.Interact_13ChEPon_307_154 Haplotypes of butyrylcholinesterase K-variant and their influence on the enzyme activity
Kadar_2019_Toxicol.Rep_6_380 The effect of antioxidants in acute amitriptyline poisoning
Levy_2019_Antioxidants.(Basel)_8_ Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview
Liu_2019_ACS.Synth.Biol_8_734 Designing of a Cofactor Self-Sufficient Whole-Cell Biocatalyst System for Production of 1,2-Amino Alcohols from Epoxides
Liu_2019_Int.J.Biol.Macromol_133_1187 Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: Kinetics and interaction mechanism merged with simulations
Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083 Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation
Ma_2019_Am.J.Alzheimers.Dis.Other.Demen__1533317519848237 Effect of CYP2D6 and CYP3A4 Genotypes on the Efficacy of Cholinesterase Inhibitors in Southern Chinese Patients With Alzheimer's Disease
Martinez-Morcillo_2019_Sci.Total.Environ_679_12 Comparative study of esterase activities in different tissues of marine fish species Trachurus trachurus, Merluccius merluccius and Trisopterus luscus
Obara_2019_Pharmacology_104_43 Inhibition of Recombinant Human Acetylcholinesterase Activity by Antipsychotics
Pardeshi_2019_Front.Pharmacol_10_288 Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer's Disease-Like Complications of Diabetes
Ren_2019_Medicine.(Baltimore)_98_e15528 Liver function and energy metabolism in hepatocellular carcinoma developed in patients with hepatitis B-related cirrhosis
Stalinska_2019_Transl.Oncol_12_895 Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential
Teng_2019_Lipids.Health.Dis_18_111 Pleiotropic association of LIPC variants with lipid and urinary 8-hydroxy deoxyguanosine levels in a Taiwanese population
Yadav_2019_Open.Access.Maced.J.Med.Sci_7_1059 Neuroprotective Activity of Evolvulus alsinoides & Centella asiatica Ethanolic Extracts in Scopolamine-Induced Amnesia in Swiss Albino Mice
Yang_2019_Int.J.Environ.Res.Public.Health_16_ Biomarker Effects in Carassius auratus Exposure to Ofloxacin, Sulfamethoxazole and Ibuprofen
Yeh_2019_Neuroreport_30_567 Inhibition of soluble epoxide hydrolase regulates monocyte\/macrophage polarization and improves neurological outcome in a rat model of ischemic stroke
Yu_2019_Fitoterapia_135_99 Absolute structure assignment of an iridoid-monoterpenoid indole alkaloid hybrid from Dipsacus asper
Verma_2019_3.Biotech_9_165 Identification of new members of alkaliphilic lipases in archaea and metagenome database using reconstruction of ancestral sequences
Chauhdary_2019_Pak.J.Pharm.Sci_32_805 Neuroprotective evaluation of Tribulus terrestris L. in aluminum chloride induced Alzheimer's disease
Eftekhari_2019_Iran.J.Pharm.Res_18_412 Oliveria decumbens, a Bioactive Essential Oil: Chemical Composition and Biological Activities
Ek_2019_PLoS.One_14_e0211304 Increase in stable isotope ratios driven by metabolic alterations in amphipods exposed to the beta-blocker propranolol
Essa_2019_Vet.World_12_440 Nanoparticles of zinc oxide defeat chlorpyrifos-induced immunotoxic effects and histopathological alterations
Ewere_2019_Chemosphere_230_1 Uptake, depuration and sublethal effects of the neonicotinoid, imidacloprid, exposure in Sydney rock oysters
Hageman_2019_Clin.Toxicol.(Phila)__1 Three patients with probable aerotoxic syndrome
Hai_2019_Crit.Care.Med_47_e144 Monoacylglycerol Lipase Inactivation by Using URB602 Mitigates Myocardial Damage in a Rat Model of Cardiac Arrest
Huang_2019_PLoS.One_14_e0215248 Risk of cardiovascular events associated with dipeptidyl peptidase-4 inhibitors in patients with diabetes with and without chronic kidney disease: A nationwide cohort study
Kumar_2019_Indian.J.Clin.Biochem_34_240 beta-Naphthyl Acetate in Acetone Produces a Dark Background for Staining of Esterase Activity on Gel
Lin_2019_PeerJ_7_e6887 Galantamine plasma concentration and cognitive response in Alzheimer's disease
Maharajan_2019_J.Biomol.Struct.Dyn__1 Discovery of new potential triplet acting inhibitor for Alzheimer disease via X-ray Crystallography, Molecular Docking and Molecular Dynamics
Marrelli_2019_Nat.Prod.Res__1 Cryptotanshinone and tanshinone IIA from Salvia milthorrhiza Bunge (Danshen) as a new class of potential pancreatic lipase inhibitors
Naranjo_2019_Prog.Neuropsychopharmacol.Biol.Psychiatry__109640 Effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly I:C rat model of schizophrenia
Nascimento_2019_Biotechnol.Prog__e2838 Effects of cholinium-based ionic liquids on Aspergillus niger lipase: stabilizers or inhibitors
Noguchi_2019_Pharmazie_74_305 Association between dipeptidyl peptidase-4 inhibitors and autoimmune disorders: Data mining of the spontaneous reporting system in Japan
Rajawat_2019_Toxicol.Ind.Health_35_358 Effect of beta-cyfluthrin (synthetic pyrethroid) on learning, muscular coordination and oxidative stress in Swiss albino mice
Reyes-Espinosa_2019_Int.J.Mol.Sci_20_ In Silico Study of the Resistance to Organophosphorus Pesticides Associated with Point Mutations in Acetylcholinesterase of Lepidoptera: B. mandarina, B. mori, C. auricilius, C. suppressalis, C. pomonella, H. armigera, P. xylostella, S. frugiperda, and S. litura
Rodrigues_2019_Redox.Rep_24_34 Protection of cholinergic and antioxidant system contributes to the effect of Vitamin D3 ameliorating memory dysfunction in sporadic dementia of Alzheimer's type
Seppey_2019_Genome.Biol_20_98 Genomic signatures accompanying the dietary shift to phytophagy in polyphagan beetles
Shaik_2019_Bioorg.Chem_88_102960 Synthesis and biological evaluation of flavone-8-acrylamide derivatives as potential multi-target-directed anti Alzheimer agents and investigation of binding mechanism with acetylcholinesterase
Toropov_2019_Sci.Total.Environ_659_1387 The study of the index of ideality of correlation as a new criterion of predictive potential of QSPR\/QSAR-models
Vaughan_2019_Ir.J.Psychol.Med__1 Anticholinergic burden of patients with dementia attending a Psychiatry of Later Life service
Wang_2019_Nat.Prod.Res__1 Inducing secondary metabolite production from Daldinia eschscholzii JC-15 by red ginseng medium
Zhang_2019_Mar.Drugs_17_ Polyketides from the Mangrove-Derived Endophytic Fungus Cladosporium cladosporioides
Zhang_2019_Eur.J.Med.Chem_176_228 Multi-target design strategies for the improved treatment of Alzheimer's disease
Bigley_2019_Chem.Biol.Interact_13ChEPon_308_80 The evolution of phosphotriesterase for decontamination and detoxification of organophosphorus chemical warfare agents
Auti_2019_Front.Neurol_10_399 Neuroprotective Effect of Cardamom Oil Against Aluminum Induced Neurotoxicity in Rats
Chen_2019_Insect.Sci_26_843 Insecticide toxicity associated with detoxification enzymes and genes related to transcription of cuticular melanization among color morphs of Asian citrus psyllid
He_2019_Environ.Pollut_251_746 A transcriptomics-based analysis of the toxicity mechanisms of gabapentin to zebrafish embryos at realistic environmental concentrations
Hu_2019_J.Enzyme.Inhib.Med.Chem_34_1083 Synthesis and biological evaluation of 3-(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer's disease agents
Hussein_2019_In.Silico.Pharmacol_7_3 Computational insight to putative anti-acetylcholinesterase activity of Commiphora myrrha (Nees), Engler, Burseraceae: a lessen of archaeopharmacology from Mesopotamian Medicine I
Kara_2019_Arch.Pharm.(Weinheim)__e1800310 Synthesis of 2-(2-oxo-2H-chromen-4-yl)acetamides as potent acetylcholinesterase inhibitors and molecular insights into binding interactions
Liu_2019_Nat.Prod.Res__1 New biphenanthrenes with butyrylcholinesterase inhibitory activitiy from Cremastra appendiculata
Oshima_2019_Int.Psychogeriatr__1 Competency of aMCI patients to consent to cholinesterase treatment
Rukachaisirikul_2019_Nat.Prod.Res__1 A new pyrrole alkaloid from the roots of Cissampelos pareira
Saleem_2019_Medicina.(Kaunas)_55_ Experimental and Computational Studies to Characterize and Evaluate the Therapeutic Effect of Albizia lebbeck (L.) Seeds in Alzheimer's Disease
Sandoval_2019_Sci.Total.Environ_683_445 Effects of chlorpyrifos on cell death and cellular phenotypic specification of human neural stem cells
Shamsimeymandi_2019_Arch.Pharm.(Weinheim)__e1800352 Design, synthesis, biological evaluation, and molecular dynamics of novel cholinesterase inhibitors as anti-Alzheimer's agents
Sut_2019_J.Pharm.Biomed.Anal_173_75 Influence of different extraction techniques on the chemical profile and biological properties of Anthemis cotula L.: Multifunctional aspects for potential pharmaceutical applications
Teles_2019_Front.Physiol_10_523 Transport and Recovery of Gilthead Sea Bream (Sparus aurata L.) Sedated With Clove Oil and MS222: Effects on Oxidative Stress Status
Triassi_2019_Sci.Total.Environ_678_741 Ecological risk and estimates of organophosphate pesticides loads into the Central Mediterranean Sea from Volturno River, the river of the Land of Fires area, southern Italy
Turkan_2019_Arch.Physiol.Biochem__1 Investigation of the toxicological and inhibitory effects of some benzimidazole agents on acetylcholinesterase and butyrylcholinesterase enzymes
Turkan_2019_Arch.Pharm.(Weinheim)__e1800359 Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives
Turkes_2019_Bioorg.Chem_89_103004 Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and acetylcholinesterase inhibitors
Vogel_2019_Ment.Health.Clin_9_128 Donepezil-induced QTc prolongation: A case report
Wu_2019_Eur.J.Med.Chem_177_198 Design, synthesis, and biological evaluation of rutacecarpine derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease
Xu_2019_Anal.Chim.Acta_1071_1 Converting solution viscosity to distance-readout on paper substrates based on enzyme-mediated alginate hydrogelation: Quantitative determination of organophosphorus pesticides
Zhao_2019_Fa.Yi.Xue.Za.Zhi_35_143 Time-dependent Expression and Distribution of AChE during the Skin Incised Wound Healing in Mice
An_2019_Nutrients_11_ Ginsenosides Rg5 and Rk1 Enriched Cultured Wild Ginseng Root Extract Bioconversion of Pediococcus pentosaceus HLJG0702: Effect on Scopolamine-Induced Memory Dysfunction in Mice
Bibi_2019_J.Pharm.Biomed.Anal_174_19 Chemical profiling, antioxidant, enzyme inhibitory and molecular modelling studies on the leaves and stem bark extracts of three African medicinal plants
Cao_2019_Mikrochim.Acta_186_390 Rapid colorimetric determination of the pesticides carbofuran and dichlorvos by exploiting their inhibitory effect on the aggregation of peroxidase-mimicking platinum nanoparticles
Chambers_2019_Neurobiol.Dis__104487 Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX
Citterio_2019_Nat.Rev.Endocrinol_15_323 The role of thyroglobulin in thyroid hormonogenesis
Duarte_2019_ChemistryOpen_8_627 Experimental and Theoretical Approaches in the Study of Phenanthroline-Tetrahydroquinolines for Alzheimer's Disease
Efjestad_2019_Dement.Geriatr.Cogn.Dis.Extra_9_196 Drug Use before and after Initiating Treatment with Acetylcholinesterase Inhibitors
El-Hawary_2019_Nat.Prod.Res__1 Anticholinesterase activity and metabolite profiling of Syagrus romanzoffiana (Cham.) Glassman leaves and fruits via UPLC-QTOF-PDA-MS
Fernandez-Cabezudo_2019_Front.Immunol_10_1038 Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes
Fotiadou_2019_Nanomaterials.(Basel)_9_ Development of Effective Lipase-Hybrid Nanoflowers Enriched with Carbon and Magnetic Nanomaterials for Biocatalytic Transformations
Gholivand_2019_Pestic.Biochem.Physiol_157_122 Synthesis, crystal structure, insecticidal activities, molecular docking and QSAR studies of some new phospho guanidines and phospho pyrazines as cholinesterase inhibitors
Ghorbani_2019_Int.J.Prev.Med_10_45 Evaluating the Protective Role of Ascorbic Acid in Malathion-induced Testis Tissue Toxicity of Male Rats
Holtkamp_2019_PLoS.One_14_e0217269 A novel understanding of postoperative complications: In vitro study of the impact of propofol on epigenetic modifications in cholinergic genes
Huang_2019_Eur.J.Med.Chem_177_247 Development of the hidden multifunctional agents for Alzheimer's disease
Kanadome_2019_Methods.Mol.Biol_2009_83 Systematic Screening of Depalmitoylating Enzymes and Evaluation of Their Activities by the Acyl-PEGyl Exchange Gel-Shift (APEGS) Assay
Kumar_2019_Eur.J.Med.Chem_177_221 Dipropargyl substituted diphenylpyrimidines as dual inhibitors of monoamine oxidase and acetylcholinesterase
Kumar_2019_Anal.Chim.Acta_1074_131 Electrochemical biosensor for methyl parathion based on single-walled carbon nanotube\/glutaraldehyde crosslinked acetylcholinesterase-wrapped bovine serum albumin nanocomposites
Li_2019_Eur.J.Pharmacol__172423 NLGN3 promotes neuroblastoma cell proliferation and growth through activating PI3K\/AKT pathway
Liu_2019_Fitoterapia__104184 New phthalide derivatives from the Biscogniauxia sp. and their activities
Marcinkowska_2019_Arch.Pharm.(Weinheim)__e1900041 Anti-Alzheimer's multitarget-directed ligands with serotonin 5-HT6 antagonist, butyrylcholinesterase inhibitory, and antioxidant activity
Moshfegh_2019_Front.Behav.Neurosci_13_103 Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress
Nissankara_2019_Nutr.Neurosci__1 Protective effect of Curcuma amada acetone extract against high-fat and high-sugar diet-induced obesity and memory impairment
Patil_2019_PLoS.One_14_e0215291 Comparative biophysical characterization: A screening tool for acetylcholinesterase inhibitors
Peltzer_2019_Sci.Total.Environ_683_624 Biotoxicity of diclofenac on two larval amphibians: Assessment of development, growth, cardiac function and rhythm, behavior and antioxidant system
Pundir_2019_Biosens.Bioelectron_140_111348 Bio-sensing of organophosphorus pesticides: A review
Purgatorio_2019_Eur.J.Med.Chem_177_414 Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease
Rocha-Resende_2019_JCI.Insight_5_ Immunomodulatory role of non-neuronal cholinergic signaling in myocardial injury
Salama_2019_Pestic.Biochem.Physiol_157_13 Modulatory effects of swimming exercise against malathion induced neurotoxicity in male and female rats
Seidl_2019_Anal.Chim.Acta_1072_81 A novel on-flow mass spectrometry-based dual enzyme assay
Sinko_2019_Chem.Biol.Interact_13ChEPon_308_216 Assessment of scoring functions and in silico parameters for AChE-ligand interactions as a tool for predicting inhibition potency
Sohn_2019_Nutrients_11_ Elaeagnus glabra f. oxyphylla Attenuates Scopolamine-Induced Learning and Memory Impairments in Mice by Improving Cholinergic Transmission via Activation of CREB\/NGF Signaling
Suarez-Lopez_2019_Environ.Res_175_335 Blood pressure after a heightened pesticide spray period among children living in agricultural communities in Ecuador
Sun_2019_Ann.Gen.Psychiatry_18_6 Analysis of the SNP rs3747333 and rs3747334 in NLGN4X gene in autism spectrum disorder: a meta-analysis
Tabbabi_2019_Afr.Health.Sci_19_1368 The potential role of urbanization in the resistance to organophosphate insecticide in Culex pipiens pipiens from Tunisia
Tabbabi_2019_Afr.Health.Sci_19_1361 Evaluation of resistance to temephos insecticide in Culex pipiens pipiens larvae collected from three districts of Tunisia
Therkildsen_2019_Clin.Exp.Rheumatol_37 Suppl 117_20 Acetylcholinesterase-associated inflammation in patients with giant cell arteritis. Evaluation by histology and 11C-donepezil PET\/CT
Dhananjayan_2019_Mutat.Res_841_1 Assessment of genotoxicity and cholinesterase activity among women workers occupationally exposed to pesticides in tea garden
Verny_2019_Geriatr.Psychol.Neuropsychiatr.Vieil_17_189 Lewy body dementia: therapeutic propositions according to evidence based medicine and practice
Wang_2019_Appl.Microbiol.Biotechnol_103_4077 Enhancing the atypical esterase promiscuity of the gamma-lactamase Sspg from Sulfolobus solfataricus by substrate screening
Wu_2019_J.Environ.Manage_245_168 The removal of cyhalofop-butyl in soil by surplus Rhodopseudanonas palustris in wastewater purification
Yannick_2019_Nat.Prod.Res__1 Crotoliganfuran, a new clerodane-type furano-diterpenoid from Croton oligandrus Pierre ex Hutch
Zou_2019_Fitoterapia__104186 New amide alkaloids from Delphinium brunonianum
Cenik_2019_Dev.Cell_48_811 Maternal Ribosomes Are Sufficient for Tissue Diversification during Embryonic Development in C. elegans
Dean_2019_J.Affect.Disord_244_80 Changes in levels of cortical metabotropic glutamate 2 receptors with gender and suicide but not psychiatric diagnoses
Dean_2019_J.Affect.Disord_243_539 Cortical biometals: Changed levels in suicide and with mood disorders
Dean_2019_World.J.Biol.Psychiatry__1 Changes in cortical protein markers of iron transport with gender, major depressive disorder and suicide
Gefen_2019_Front.Aging.Neurosci_11_94 Activated Microglia in Cortical White Matter Across Cognitive Aging Trajectories
Gerwin_2019_J.Physiol_597_1993 Acetylcholine receptors in the equatorial region of intrafusal muscle fibres modulate mouse muscle spindle sensitivity
Handara_2019_Dev.Biol_445_54 The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons
Kim_2019_J.Neuropathol.Exp.Neurol_78_229 Morphology and Distribution of TDP-43 Pre-inclusions in Primary Progressive Aphasia
Liang_2019_Neuron_102_843 Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay
Mesulam_2019_Neurology_92_e224 Word comprehension in temporal cortex and Wernicke area: A PPA perspective
Noblett_2019_J.Cell.Biol_218_125 DIP-2 suppresses ectopic neurite sprouting and axonal regeneration in mature neurons
Ohm_2019_Neuropathol.Appl.Neurobiol_45_216 Prominent microglial activation in cortical white matter is selectively associated with cortical atrophy in primary progressive aphasia
Parkin_2019_Electrophoresis_40_247 Beta-actin does not show the characteristics of a reference protein in human cortex
Pottier_2019_Acta.Neuropathol_137_879 Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD
Rogalski_2019_Hippocampus_29_458 Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first 10 cases
Ukai_2019_Curr.Opin.Biotechnol_58_137 Next-generation human genetics for organism-level systems biology
Gonzalez_2019_Expert.Opin.Drug.Discov__1 Developments with multi-target drugs for Alzheimer's disease: an overview of the current discovery approaches
Mzik_2019_J.Pharm.Biomed.Anal_174_134 UHPLC-HRMS study of anti-Alzheimer's drug candidates: metabolism of 7-MEOTA-tryptophan hybrids hampers their passage into brain
Abu-Aisheh_2019_Heliyon_5_e01552 Coumarin derivatives as acetyl- and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics simulations study
Ahuja_2019_Pharmacol.Rep_71_614 Alpha lipoic acid and metformin alleviates experimentally induced insulin resistance and cognitive deficit by modulation of TLR2 signalling
Atmaca_2019_Bioorg.Chem_88_102980 Synthesis of oxazolidinone from enantiomerically enriched allylic alcohols and determination of their molecular docking and biologic activities
Belinskaia_2019_Comput.Biol.Chem_80_452 Rational in silico design of aptamers for organophosphates based on the example of paraoxon
Boztas_2019_Bioorg.Chem_89_103017 Synthesis and biological evaluation of bromophenol derivatives with cyclopropyl moiety: Ring opening of cyclopropane with monoester
Burmaoglu_2019_Arch.Physiol.Biochem__1 Synthesis of novel tris-chalcones and determination of their inhibition profiles against some metabolic enzymes
Chiarla_2019_Mediators.Inflamm_2019_5012874 Comment on A Sustained Reduction in Serum Cholinesterase Enzyme Activity Predicts Patient Outcome following Sepsis
Heroux_2019_Neurobiol.Learn.Mem__107030 Cholinergic rescue of neurocognitive insult following third-trimester equivalent alcohol exposure in rats
Jiang_2019_Bioorg.Chem_89_103027 Novel chromanone-dithiocarbamate hybrids as multifunctional AChE inhibitors with beta-amyloid anti-aggregation properties for the treatment of Alzheimer's disease
Manouchehrizadeh_2019_Comput.Biol.Chem_80_463 Alignment-independent 3D-QSAR and molecular docking studies of tacrine-4-oxo-4H-Chromene hybrids as anti-Alzheimer's agents
Mizoi_2019_Xenobiotica__1 Structure-activity relationship of atorvastatin derivatives for metabolic activation by hydrolases
Mohtar_2019_PeerJ_7_e6880 Spray-dried immobilized lipase from Geobacillus sp. strain ARM in sago
Quartier_2019_Hum.Mutat_40_2021 Novel mutations in NLGN3 causing autism spectrum disorder and cognitive impairment
Rosenberry_2019_Chem.Biol.Interact_13ChEPon_ Rate-limiting step in the decarbamoylation of acetylcholinesterases with large carbamoyl groups
Schreiber_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_880 Of mice and men: The physiological role of adipose triglyceride lipase (ATGL)
Song_2019_Chem.Biol.Interact_13ChEPon_308_339 Inhibition of human carboxylesterases by magnolol: Kinetic analyses and mechanism
Stojan_2019_Chem.Biol.Interact_13ChEPon_308_350 The mechanism and benefit of human butyrylcholinesterase activation by what would otherwise be inhibitors
Xu_2019_Chem.Biol.Interact_13ChEPon_308_317 Differentiation of erythroblast requires the dimeric form of acetylcholinesterase: Interference with erythropoietin receptor
Xu_2019_Nat.Prod.Res__1 Chemical composition and biological activities of an essential oil from the aerial parts of Artemisia Gmelinii weber ex Stechm
Yerlikaya_2019_J.Pharm.Biomed.Anal_174_286 Investigation of chemical profile, biological properties of Lotus corniculatus L. extracts and their apoptotic-autophagic effects on breast cancer cells
Zhao_2019_Ecotoxicol.Environ.Saf_181_138 Accumulation, biodegradation and toxicological effects of N-ethyl perfluorooctane sulfonamidoethanol on the earthworms Eisenia fetida exposed to quartz sands
Lee_2019_Evid.Based.Complement.Alternat.Med_2019_1304152 Central and Peripheral Mechanism of Acupuncture Analgesia on Visceral Pain: A Systematic Review
Maximova_2019_J.Clin.Med_8_ Drop of Butyrylcholinesterase Activity after Cyclophosphamide Conditioning as a Predictive Marker of Liver Transplant-Related Complications and Its Correlation with Transplant-Related Mortality in Pediatric Hematopoietic Stem Cell Recipients
Tamimi_2019_J.Musculoskelet.Neuronal.Interact_19_249 Addendum: Effect of acetylcholinesterase inhibitors on post-surgical complications and mortality following a hip fracture: a cohort study
Verma_2019_Open.Biol_9_180265 Understanding intellectual disability and autism spectrum disorders from common mouse models: synapses to behaviour
Zeman_2019_Enzyme.Microb.Technol_128_26 Tubes for detection of cholinesterase inhibitors-Unique effects of Neusilin on the stability of butyrylcholinesterase-impregnated carriers
Campbell_2019_Aquat.Toxicol_213_105221 Functionalized silver nanoparticles depress aerobic metabolism in the absence of overt toxicity in brackish water killifish, Fundulus heteroclitus
Eldufani_2019_Alzheimers.Dement.(N.Y)_5_175 The role of acetylcholinesterase inhibitors such as neostigmine and rivastigmine on chronic pain and cognitive function in aging: A review of recent clinical applications
Han_2019_Diabetes.Metab.Syndr.Obes_12_685 Plasma cholinesterase is associated with Chinese adolescent overweight or obesity and metabolic syndrome prediction
Hayes_2019_Appl.Radiat.Isot_151_182 Divergent synthesis of organophosphate [(11)C]VX- and [(11)C]Sarin-surrogates from a common set of starting materials
Hussain_2019_Molecules_24_ Putative Roles of Plant-Derived Tannins in Neurodegenerative and Neuropsychiatry Disorders: An Updated Review
Jin_2019_Artif.Cells.Nanomed.Biotechnol_47_2338 Association between EPHX1 polymorphism rs1051740 and the risk of ovarian cancer: a meta-analysis
Kumar_2019_Exp.Appl.Acarol_78_149 Molecular markers and their application in the monitoring of acaricide resistance in Rhipicephalus microplus
Lee_2019_Bioorg.Chem_89_103043 Potent inhibition of acetylcholinesterase by sargachromanol I from Sargassum siliquastrum and by selected natural compounds
Muhammad_2019_Heliyon_5_e01758 Synthesis, crystal structures, Hirshfeld surface analysis and spectroscopic studies of two Schiff bases of anisaldehyde and their urease and acetylcholinesterase inhibitory and antioxidant properties
Ningthoujam_2019_Alzheimers.Dement.(N.Y)_5_154 In vitro degradation of beta-amyloid fibrils by microbial keratinase
Ono_2019_Front.Pharmacol_10_559 Pharmacological Potential of Cilostazol for Alzheimer's Disease
Paquet-Walsh_2019_Sci.Total.Environ_685_690 Interactive effects of neonicotinoids and natural ultraviolet radiation on yellow perch (Perca flavescens) larvae
Scipioni_2019_Medchemcomm_10_764 Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease
Snieckute_2019_Mol.Cell.Neurosci_98_70 mir-234 controls neuropeptide release at the Caenorhabditis elegans neuromuscular junction
Tarazona_2019_Elife_8_ Evolution of limb development in cephalopod mollusks
Tober_2019_BMC.Complement.Altern.Med_19_128 Modulation of neurological pathways by Salvia officinalis and its dependence on manufacturing process and plant parts used
Urquhart_2019_Neurobiol.Stress_10_100164 Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex
Pereira_2019_Chem.Biol.Interact_13ChEPon_308_323 Development of technologies applied to the biodegradation of warfare nerve agents: Theoretical evidence for asymmetric homogeneous catalysis
Ahmed-Chaouch_2019_Nat.Prod.Res__1 Chemical composition, in vitro antioxidant, anticholinesterase and antibacterial activities of Linaria scariosa Desf
Cao_2019_Bioorg.Chem_90_103030 Isolation and characterization of three pairs of indolediketopiperazine enantiomers containing infrequent N-methoxy substitution from the marine algal-derived endophytic fungus Acrostalagmus luteoalbus TK-43
Costa_2019_Sci.Rep_9_8795 Shared Molecular Signatures Across Neurodegenerative Diseases and Herpes Virus Infections Highlights Potential Mechanisms for Maladaptive Innate Immune Responses
Erukainure_2019_J.Ethnopharmacol__112033 The antidiabetic properties of the hot water extract of kola nut (Cola nitida (Vent.) Schott & Endl.) in type 2 diabetic rats
Garcia-Gomez_2019_Sci.Total.Environ_688_199 Joint effects of zinc oxide nanoparticles and chlorpyrifos on the reproduction and cellular stress responses of the earthworm Eisenia andrei
Giessel_2019_Bioorg.Chem_90_103058 Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase
Huang_2019_Food.Chem.Toxicol_131_110596 Effects of dietary exposure to chlorpyrifos on immune cell populations and inflammatory responses in mice with dextran sulfate sodium-induced colitis
Jia_2019_Anal.Cell.Pathol.(Amst)_2019_8253850 Tempol Attenuates Neuropathic Pain by Inhibiting Nitric Oxide Production
Kegler_2019_Gene_711_143924 Involvement of MnSOD Ala16Val polymorphism in epilepsy: A relationship with seizure type, inflammation, and metabolic syndrome
Kwon_2019_Oxid.Med.Cell.Longev_2019_7849876 Chronic Alcohol Exposure Induced Neuroapoptosis: Diminishing Effect of Ethyl Acetate Fraction from Aralia elata
Li_2019_Chemosphere_234_204 Transformation pathway and toxicity assessment of malathion in aqueous solution during UV photolysis and photocatalysis
Lol_2019_Malar.J_18_202 Development of molecular assays to detect target-site mechanisms associated with insecticide resistance in malaria vectors from Latin America
Metais_2019_Mar.Pollut.Bull_142_178 Is there a link between acetylcholinesterase, behaviour and density populations of the ragworm Hediste diversicolor?
Nguyen_2019_Carbohydr.Polym_218_126 Enzymatic synthesis and characterization of maltoheptaose-based sugar esters
Nuthakki_2019_Bioorg.Chem_90_103062 Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors
Ploskonka_2019_J.Hazard.Mater_375_191 Insight into organophosphate chemical warfare agent simulant hydrolysis in metal-organic frameworks
Pohanka_2019_Bratisl.Lek.Listy_120_397 Copper and copper nanoparticles toxicity and their impact on basic functions in the body
Punchihewa_2019_Parasit.Vectors_12_310 Insecticide resistance mechanisms with novel 'kdr' type gene mutations in the tropical bed bug Cimex hemipterus
Ringman_2019_Curr.Treat.Options.Neurol_21_30 Treatment Options for Agitation in Dementia
Su_2019_Bull.Entomol.Res__1 Comparative transcriptome profiling reveals candidate genes related to insecticide resistance of Glyphodes pyloalis
Suo_2019_J.Colloid.Interface.Sci_553_494 Enhanced catalytic performance of lipase covalently bonded on ionic liquids modified magnetic alginate composites
Walpitagama_2019_Aquat.Toxicol_213_105227 Additives migrating from 3D-printed plastic induce developmental toxicity and neuro-behavioural alterations in early life zebrafish (Danio rerio)
Watari_2019_Evid.Based.Complement.Alternat.Med_2019_4086749 Kihito, a Traditional Japanese Kampo Medicine, Improves Cognitive Function in Alzheimer's Disease Patients
Zengin_2019_J.Pharm.Biomed.Anal_174_406 Chemical profiling of Centaurea bornmuelleri Hausskn. aerial parts by HPLC-MS\/MS and their pharmaceutical effects: From nature to novel perspectives
Zhou_2019_Am.J.Transl.Res_11_3056 Buyang Huanwu Tang alleviates inflammation and improves motor endplate functions in DSMA rat models by activating several biological molecules and associated signaling pathways
Zhou_2019_Front.Pharmacol_10_603 Shen-Yuan-Dan Capsule Attenuates Atherosclerosis and Foam Cell Formation by Enhancing Autophagy and Inhibiting the PI3K\/Akt\/mTORC1 Signaling Pathway
Meng_2019_Appl.Biochem.Biotechnol__ Cloning, Characterization, and Functional Expression of a Thermostable Type B Feruloyl Esterase from Thermophilic Thielavia Terrestris
Alves_2019_Mar.Drugs_17_ A New Meroterpene, A New Benzofuran Derivative and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Acremonium persicinum KUFA 1007 and Their Anticholinesterase Activities
Arque_2019_Nat.Commun_10_2826 Intrinsic enzymatic properties modulate the self-propulsion of micromotors
Ben Haj Yahia_2019_Molecules_24_ Polyphenolic Profiling, Quantitative Assessment and Biological Activities of Tunisian Native Mentha rotundifolia (L.) Huds
Bruno_2019_J.Psychopharmacol__269881119858304 Brain circuitry, behavior, and cognition: A randomized placebo-controlled trial of donepezil in fragile X syndrome
Cui_2019_Biosens.Bioelectron_141_111452 An acetylcholinesterase biosensor based on doping Au nanorod@SiO2 nanoparticles into TiO2-chitosan hydrogel for detection of organophosphate pesticides
da Fonseca_2019_Environ.Pollut_252_1180 Effects of mixtures of anticancer drugs in the benthic polychaete Nereis diversicolor
de Matos_2019_Pharmaceuticals.(Basel)_12_ Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Abeta1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells
Ecimovic_2019_Chemosphere_234_837 Biomarker responses in earthworm coelomocyte extract - Noninvasively collected sample for pesticide effect assessment
Firpo_2019_Antioxidants.(Basel)_8_ Evaluation of the Antioxidant Activity of Cis\/Trans-N-Phenyl-1,4,4a,5,8,8a-Hexahydro-3,1-Benzoxazin-2-Imines
Han_2019_Chin.J.Nat.Med_17_475 Bioactive phenazines from an earwig-associated Streptomyces sp
Hulcova_2019_Phytochemistry_165_112055 Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease
Jia_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_224_108561 P8 nuclear receptor responds to acaricides exposure and regulates transcription of P450 enzyme in the two-spotted spider mite, Tetranychus urticae
Kaaniche_2019_PLoS.One_14_e0217627 Bioactive secondary metabolites from new endophytic fungus Curvularia. sp isolated from Rauwolfia macrophylla
Kobus-Cisowska_2019_Nutrients_11_ Composition and In Vitro Effects of Cultivars of Humulus lupulus L. Hops on Cholinesterase Activity and Microbial Growth
Mahgoub_2019_Molecules_24_ Synthesis, Crystal Structure, and Biological Evaluation of Fused Thiazolo[3,2-a]Pyrimidines as New Acetylcholinesterase Inhibitors
Mendonca_2019_Nat.Prod.Res__1 Plinia cauliflora (Mart.) Kausel: toxicological assays, biological activities, and elemental analysis of organic compounds
Morroni_2019_Front.Pharmacol_10_658 PQM130, a Novel Feruloyl-Donepezil Hybrid Compound, Effectively Ameliorates the Cognitive Impairments and Pathology in a Mouse Model of Alzheimer's Disease
Obara_2019_Biol.Pharm.Bull_42_1064 Effects of Distigmine on the Mechanical Activity of Urinary Bladder Smooth Muscle
O'Caoimh_2019_Maturitas_126_1 Reducing inappropriate prescribing for older adults with advanced frailty: A review based on a survey of practice in four countries
Osmaniye_2019_Molecules_24_ Synthesis and AChE Inhibitory Activity of Novel Thiazolylhydrazone Derivatives
Pinnell_2019_Front.Microbiol_10_1252 Shotgun Metagenomics Reveals the Benthic Microbial Community Response to Plastic and Bioplastic in a Coastal Marine Environment
Sizonov_2019_Bull.Exp.Biol.Med_167_220 Changes in Activities of Somatovisceral Systems in Newborn Rats under Conditions of Nicotinic Cholinoreceptor Blockage and Activation of Cholinoreactive Structures
Slotkin_2019_Toxicology__152240 Perinatal diazinon exposure compromises the development of acetylcholine and serotonin systems
Tzvetkov_2019_Eur.J.Med.Chem_179_404 Carboxamides vs. methanimines: Crystal structures, binding interactions, photophysical studies, and biological evaluation of (indazole-5-yl)methanimines as monoamine oxidase B and acetylcholinesterase inhibitors
Xiao_2019_Neurobiol.Aging_81_77 ABAD\/17beta-HSD10 reduction contributes to the protective mechanism of huperzine a on the cerebral mitochondrial function in APP\/PS1 mice
Karasova_2019_Drug.Chem.Toxicol__1 Tacrine and its 7-methoxy derivate\; time-change concentration in plasma and brain tissue and basic toxicological profile in rats
Ahren_2019_Front.Endocrinol.(Lausanne)_10_376 DPP-4 Inhibition and the Path to Clinical Proof
Alavinia_2019_Ecotoxicol.Environ.Saf_182_109311 DNA damage, acetylcholinesterase activity, and hematological responses in rainbow trout exposed to the organophosphate malathion
Cui_2019_Medicine.(Baltimore)_98_e16091 The effect of anti-dementia drugs on Alzheimer disease-induced cognitive impairment: A network meta-analysis
Glinz_2019_Swiss.Med.Wkly_149_w20093 Acetylcholinesterase inhibitors combined with memantine for moderate to severe Alzheimer's disease: a meta-analysis
Gutti_2019_Bioorg.Chem_90_103080 Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer's disease
Hung_2019_J.Neuroinflammation_16_123 Soluble epoxide hydrolase modulates immune responses in activated astrocytes involving regulation of STAT3 activity
Hye_2019_Biochem.Pharmacol_166_212 A dual farnesoid X receptor\/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice
Jain_2019_Crit.Rev.Toxicol__1 Advances in detection of hazardous organophosphorus compounds using organophosphorus hydrolase based biosensors
Jonczyk_2019_Bioorg.Chem_90_103084 Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives
Kawada_2019_J.Agric.Food.Chem_67_6143 Synthesis and Biological Evaluation of Novel Triazole Derivatives as Strigolactone Biosynthesis Inhibitors
Kim_2019_Int.J.Biol.Macromol_135_1202 Isolation of soluble epoxide hydrolase inhibitor of capsaicin analogs from Capsicum chinense Jacq. cv. Habanero
Klocke_2019_Sci.Rep_9_8993 Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB\/W F1 mice
Liu_2019_iScience_17_144 Strigolactones Play an Important Role in Shaping Exodermal Morphology via a KAI2-Dependent Pathway
Loesche_2019_Bioorg.Chem_90_103092 Novel 12-hydroxydehydroabietylamine derivatives act as potent and selective butyrylcholinesterase inhibitors
Marsalek_2019_Microb.Cell.Fact_18_119 Disruption of vacuolar protein sorting components of the HOPS complex leads to enhanced secretion of recombinant proteins in Pichia pastoris
Marzec_2019_Trends.Plant.Sci_24_571 Binding or Hydrolysis? How Does the Strigolactone Receptor Work?
Muller_2019_An.Acad.Bras.Cienc_91_e20180419 Effects of fed mycotoxin contaminated diets supplemented with spray-dried porcine plasma on cholinergic response and behavior in piglets
Mumtaz_2019_Bioorg.Chem_90_103036 Investigation of potent inhibitors of cholinesterase based on thiourea and pyrazoline derivatives: Synthesis, inhibition assay and molecular modeling studies
Oh_2019_Int.J.Biol.Macromol_137_426 Potent and selective inhibition of human monoamine oxidase-B by 4-dimethylaminochalcone and selected chalcone derivatives
Polo_2019_Bioorg.Chem_90_103034 Ultrasound-assisted synthesis of novel chalcone, heterochalcone and bis-chalcone derivatives and the evaluation of their antioxidant properties and as acetylcholinesterase inhibitors
Ramirez_2019_Plant.Direct_3_e00149 Genetic dissection of cell wall defects and the strigolactone pathway in Arabidopsis
Savina_2019_Diab.Vasc.Dis.Res__1479164119860215 Impact of the acute local inhibition of soluble epoxide hydrolase on diabetic skin microcirculatory dysfunction
Tasanen_2019_Front.Immunol_10_1238 Dipeptidyl Peptidase-4 Inhibitor-Associated Bullous Pemphigoid
van Greunen_2019_Eur.J.Med.Chem_179_680 Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease
Vieira_2019_Environ.Toxicol.Pharmacol_71_103210 Biomarker-based assessment of the toxicity of the antifungal clotrimazol to the microcrustacean Daphnia magna
Wan_2019_Front.Pharmacol_10_464 In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea
Wang_2019_PeerJ_7_e6901 Functional analysis of the GbDWARF14 gene associated with branching development in cotton
Wang_2019_Scand.J.Immunol__e12791 Epoxyeicosatrienoic acids alleviate methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in mice
Wang_2019_Polymers.(Basel)_11_ Fabrication and Properties of a Bio-Based Biodegradable Thermoplastic Polyurethane Elastomer
Xavier_2019_Pharmaceuticals.(Basel)_12_ Synthesis and Biological Evaluation of Structurally Varied 5'-\/6'-Isonucleosides and Theobromine-Containing N-Isonucleosidyl Derivatives
Xia_2019_Anticancer.Res_39_3651 Inhibition of Pancreatic Carcinoma Growth Through Enhancing omega-3 Epoxy Polyunsaturated Fatty Acid Profile by Inhibition of Soluble Epoxide Hydrolase
Yamashita_2019_Eur.J.Pharmacol__172521 Contribution of intestinal dipeptidyl peptidase-4 inhibition for incretin-dependent improved glucose tolerance in mice
Yang_2019_Molecules_24_ Pesticide Residues Identification by Optical Spectrum in the Time-Sequence of Enzyme Inhibitors Performed on Microfluidic Paper-Based Analytical Devices (microPADs)
Akintade_2019_Clin.Med.(Lond)_19_327 Acute presentation of dementia with Lewy bodies
Araujo_2019_Chemosphere_235_885 Effects of triclosan on early development of Solea senegalensis: from biochemical to individual level
Armocida_2019_Acta.Med.Hist.Adriat_17_91 The Acetylcholine Therapy in the Treatment of Schizophrenia - The Experience of Mario Fiamberti in the Hospital of Varese (1937)
Arslan_2019_Bioorg.Chem_90_103100 Triazole substituted metal-free, metallo-phthalocyanines and their water soluble derivatives as potential cholinesterases inhibitors: Design, synthesis and in vitro inhibition study
Ayaz_2019_Front.Aging.Neurosci_11_155 Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders
Banaee_2019_Chemosphere_236_124335 Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio)
Barchuk_2019_Atherosclerosis_288_51 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 and angiopoietin-like protein 4 are associated with the increase of lipoprotein lipase activity in epicardial adipose tissue from diabetic patients
Bayindir_2019_Bioorg.Chem_90_103096 The green synthesis and molecular docking of novel N-substituted rhodanines as effective inhibitors for carbonic anhydrase and acetylcholinesterase enzymes
Beutelstetter_2019_PLoS.One_14_e0219598 Increased expression of blood muscarinic receptors in patients with reflex syncope
Bharate_2019_Environ.Toxicol.Pharmacol_71_103218 Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes
Buralli_2019_Data.Brief_25_103993 Data on pesticide exposure and mental health screening of family farmers in Brazil
Cai_2019_Chem.Biol.Interact_13ChEPon_310_108756 Dimerization of human butyrylcholinesterase expressed in bacterium for development of a thermally stable bioscavenger of organophosphorus compounds
Casu_2019_J.Environ.Sci.Health.B__1 Soluble esterases as biomarkers of neurotoxic compounds in the widespread serpulid Ficopomatus enigmaticus (Fauvel, 1923)
Chen_2019_Chemosphere_236_124365 Spectroscopic and molecular modeling investigation on inhibition effect of nitroaromatic compounds on acetylcholinesterase activity
Chen_2019_Antioxidants.(Basel)_8_ Assessment of In Vitro Bioactivities of Polysaccharides Isolated from Hericium Novae-Zealandiae
Cuya_2019_J.Biomol.Struct.Dyn__1 A molecular modeling study of components of the ginger (Zingiber officinale) extract inside human butyrylcholinesterase: implications for Alzheimer disease
Czumaj_2019_Anticancer.Res_39_3815 In Vivo Effectiveness of Orlistat in the Suppression of Human Colorectal Cancer Cell Proliferation
Darwesh_2019_Int.J.Mol.Sci_20_ Genetic Deletion or Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Cardiac Ischemia\/Reperfusion Injury by Attenuating NLRP3 Inflammasome Activation
Daskalova_2019_Food.Chem.Toxicol_132_110674 Aronia melanocarpa (Michx.) Elliot fruit juice reveals neuroprotective effect and improves cognitive and locomotor functions of aged rats
Deng_2019_Phytomedicine_63_153007 Ameliorative effect of deoxyvasicine on scopolamine-induced cognitive dysfunction by restoration of cholinergic function in mice
Deng_2019_Int.J.Biol.Macromol_138_272 Expression and characterisation of feruloyl esterases from Lactobacillus fermentum JN248 and release of ferulic acid from wheat bran
Dos Santos_2019_Nat.Prod.Res__1 Evaluation of prolyl oligopeptidase and acetylcholinesterase inhibition by Phyllanthus tenellus Roxb. from Brazil
Frukhtbeyn_2019_J.Dent.Res_98_1037 Stoichiometry and Kinetics of Sequential Dimethacrylate Enzymolysis
Giap_2019_Nat.Prod.Res__1 Chemical constituents and biological activities of the fruits of Knema pachycarpa de Wilde
Gomez-Betancur_2019_Mar.Drugs_17_ Bioactive Compounds Isolated from Marine Bacterium Vibrio neocaledonicus and Their Enzyme Inhibitory Activities
Guimaraes_2019_Food.Chem_300_125167 An efficient method for anthocyanins lipophilization based on enzyme retention in membrane systems
Hatat_2019_Front.Aging.Neurosci_11_148 A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer's Disease
Hitch_2019_PeerJ_7_e7249 A proposed update for the classification and description of bacterial lipolytic enzymes
Hope_2019_Front.Genet_10_574 The Drosophila Gene Sulfateless Modulates Autism-Like Behaviors
Jarczyk_2019_Kidney.Blood.Press.Res__1 The Cholinergic Anti-Inflammatory Pathway as a Conceptual Framework to Treat Inflammation-Mediated Renal Injury
Jiang_2019_Molecules_24_ Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-Abeta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation
Jones_2019_Front.Pharmacol_10_731 Epoxy-Oxylipins and Soluble Epoxide Hydrolase Metabolic Pathway as Targets for NSAID-Induced Gastroenteropathy and Inflammation-Associated Carcinogenesis
Keshavrzi_2019_Neuropsychobiology__1 Effect of Rivastigmine (Acetyl Cholinesterase Inhibitor) versus Placebo on Manic Episodes in Patients with Bipolar Disorders: Results from a Double Blind, Randomized, Placebo-Controlled Clinical Trial
Kim_2019_Sci.Rep_9_10342 Differential expression of acetylcholinesterase 1 in response to various stress factors in honey bee workers
Lande_2019_PLoS.One_14_e0218406 Linden (Tilia cordata) associated bumble bee mortality: Metabolomic analysis of nectar and bee muscle
Lei_2019_Nat.Prod.Res__1 Metabolites from the endophytic fungus colletotrichum sp. F168
Leung_2019_Reprod.Toxicol_89_83 Mitochondria as a target of organophosphate and carbamate pesticides: Revisiting common mechanisms of action with new approach methodologies
Li_2019_Prev.Nutr.Food.Sci_24_165 Effect of Aged Garlic Ethyl Acetate Extract on Oxidative Stress and Cholinergic Function of Scopolamine-Induced Cognitive Impairment in Mice
Liao_2019_J.Extracell.Vesicles_8_1628592 Acetylcholinesterase is not a generic marker of extracellular vesicles
Lopez_2019_Molecules_24_ Efficacy of Origanum syriacum Essential Oil against the Mosquito Vector Culex quinquefasciatus and the Gastrointestinal Parasite Anisakis simplex, with Insights on Acetylcholinesterase Inhibition
Lu_2019_Pharm.Biol_57_453 Epigenetic mechanisms underlying the effects of triptolide and tripchlorolide on the expression of neuroligin-1 in the hippocampus of APP\/PS1 transgenic mice
Luo_2019_BMC.Neurosci_20_32 An enhanced staining method K-B-2R staining for three-dimensional nerve reconstruction
Makhaeva_2019_Bioorg.Chem_91_103097 Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors
Mhatre_2019_Food.Technol.Biotechnol_57_113 Proteinaceous Pancreatic Lipase Inhibitor from the Seed of Litchi chinensis
Mughal_2019_Bioorg.Chem_91_103124 Flavonols and 4-thioflavonols as potential acetylcholinesterase and butyrylcholinesterase inhibitors: Synthesis, structure-activity relationship and molecular docking studies
Nayak_2019_J.Pediatr.Neurosci_14_42 Organophosphorus-Induced Toxic Myeloneuropathy: Series of Three Adolescent Patients with Short Review
Niu_2019_Biosens.Bioelectron_142_111495 Unprecedented peroxidase-mimicking activity of single-atom nanozyme with atomically dispersed Fe-Nx moieties hosted by MOF derived porous carbon
Panche_2019_Plants.(Basel)_8_ Multi-Target beta-Protease Inhibitors from Andrographis paniculata: In Silico and In Vitro Studies
Pashirova_2019_Chem.Biol.Interact_13ChEPon_310_108753 Delivery nanosystems based on sterically hindered phenol derivatives containing a quaternary ammonium moiety: Synthesis, cholinesterase inhibition and antioxidant activity
Pavanello_2019_Pharmacol.Res__104362 Treatment with fibrates is associated with higher LAL activity in dyslipidemic patients
Sahin_2019_Cell.Mol.Biol.(Noisy-le-grand)_65_3 Evaluation of the effects of Cyclotrichium niveum on brain acetylcholinesterase activity and oxidative stress in male rats orally exposed to lead acetate
Saika_2019_AMB.Express_9_100 Deficiency of biodegradable plastic-degrading enzyme production in a gene-deletion mutant of phyllosphere yeast, Pseudozyma antarctica defective in mannosylerythritol lipid biosynthesis
Salleh_2019_Nat.Prod.Res__1 Chemical composition and anticholinesterase inhibitory activity of the essential oil of Pseuduvaria macrophylla (Oliv.) Merr. from Malaysia
Salvadori_2019_Exp.Parasitol_204_107726 Copper oxide and closantel prevent alterations in hepatic energetic metabolism and reduce inflammation in Haemonchus contortus infection
Sanchez-Muniz_2019_Nutrients_11_ The Nutritional Components of Beer and Its Relationship with Neurodegeneration and Alzheimer's Disease
Sandoval-Herrera_2019_Sci.Rep_9_10530 Neurotoxicity of organophosphate pesticides could reduce the ability of fish to escape predation under low doses of exposure
Sattar_2019_Curr.Gastroenterol.Rep_21_33 Colonic and Anorectal Manifestations of Systemic Sclerosis
Silva_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_225_108570 Linking cholinesterase inhibition with behavioural changes in the sea snail Gibbula umbilicalis: Effects of the organophosphate pesticide chlorpyrifos
Srivastava_2019_Nat.Commun_10_3084 Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor
Surendran_2019_Parasit.Vectors_12_337 Development of the major arboviral vector Aedes aegypti in urban drain-water and associated pyrethroid insecticide resistance is a potential global health challenge
Trujillo-Chacon_2019_Food.Chem.Toxicol_132_110665 Neuroprotective activity of isoquinoline alkaloids from of Chilean Amaryllidaceae plants against oxidative stress-induced cytotoxicity on human neuroblastoma SH-SY5Y cells and mouse hippocampal slice culture
Unsal-Tan_2019_Medchemcomm_10_1018 Synthesis, molecular docking, and biological evaluation of novel 2-pyrazoline derivatives as multifunctional agents for the treatment of Alzheimer's disease
Valerio_2019_Toxicology__152250 Potential attenuation of early-life overfeeding-induced metabolic dysfunction by chronic maternal acetylcholinesterase inhibitor exposure
Vladimirova_2019_Eur.J.Pharmacol__172529 Impairment of cholinergic bladder contractility in rat model of type I diabetes complicated by cystitis: Contribution of neurotransmitter-degrading ectoenzymes
Woodman_2019_J.Vis.Exp__ Enzymatic Synthesis of Epoxidized Metabolites of Docosahexaenoic, Eicosapentaenoic, and Arachidonic Acids
Yue_2019_J.Surg.Res_244_302 MicroRNA-187 Reduces Acute Ischemic Renal Podocyte Injury via Targeting Acetylcholinesterase
Zafar_2019_Pak.J.Pharm.Sci_32_1155 Synthesis and in vitro cholinesterase inhibitory potential of dihydropyridine derivatives
Zeng_2019_Arch.Insect.Biochem.Physiol__e21597 Ambient temperature-mediated enzymic activities and intestinal microflora in Lymantria dispar larvae
Zengin_2019_Food.Res.Int_123_414 New insights into the chemical profiling, cytotoxicity and bioactivity of four Bunium species
Zhao_2019_Xenobiotica__1 Reduced systemic exposure and brain uptake of donepezil in rats with scopolamine-induced cognitive impairment
Zhou_2019_Nat.Commun_10_3068 Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein
Zivkovic_2019_Sci.Rep_9_10437 Bedside-measurement of serum cholinesterase activity predicts patient morbidity and length of the intensive care unit stay following major traumatic injury
Jamil_2019_Front.Plant.Sci_10_353 Methylation at the C-3' in D-Ring of Strigolactone Analogs Reduces Biological Activity in Root Parasitic Plants and Rice
Ademiluyi_2019_J.Food.Biochem_43_e12815 Phenolic analysis and erectogenic function of African Walnut (Tetracarpidium conophorum) seeds: The impact of the seed shell on biological activity
Ademosun_2019_Andrologia__e13371 Orange peels modulate antioxidant markers and key enzymes relevant to erection in the penile tissue of paroxetine-treated rats
Ajayi_2019_Toxicol.Rep_6_656 Evaluation of neurotoxicity and hepatotoxicity effects of acute and sub-acute oral administration of unripe ackee (Blighia sapida) fruit extract
Alabi_2019_Neurotoxicol_74_172 Methyl jasmonate abrogates rotenone-induced parkinsonian-like symptoms through inhibition of oxidative stress, release of pro-inflammatory cytokines, and down-regulation of immnopositive cells of NF-kappaB and alpha-synuclein expressions in mice
Altay_2019_J.Food.Biochem_43_e12908 Preliminary phytochemical analysis and evaluation of in vitro antioxidant, antiproliferative, antidiabetic, and anticholinergics effects of endemic Gypsophila taxa from Turkey
Atatreh_2019_J.Enzyme.Inhib.Med.Chem_34_1373 Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening
Baruah_2019_Bioimpacts_9_79 Therapeutic potency of substituted chromones as Alzheimer's drug: Elucidation of acetylcholinesterase inhibitory activity through spectroscopic and molecular modelling investigation
Ben_2019_Evid.Based.Complement.Alternat.Med_2019_9814537 LC-ESI-MS\/MS Phenolic Profile of Volutaria lippii (L.) Cass. Extracts and Evaluation of Their In Vitro Antioxidant, Antiacetylcholinesterase, Antidiabetic, and Antibacterial Activities
Bursal_2019_J.Food.Biochem_43_e12776 Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, alpha-amylase, butyrylcholinesterase, and alpha-glycosidase enzymes
Chapman_2019_Inhal.Toxicol__1 Lung damage following whole body, but not intramuscular, exposure to median lethality dose of sarin: findings in rats and guinea pigs
Dos Santos_2019_Enzyme.Res_2019_6139863 Acetylcholinesterases from Leaf-Cutting ant Atta sexdens: Purification, Characterization, and Capillary Reactors for On-Flow Assays
Eralp_2019_Res.Vet.Sci_125_290 Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration
Erukainure_2019_J.Food.Biochem_43_e12764 Raffia palm (Raphia hookeri) wine extenuates redox imbalance and modulates activities of glycolytic and cholinergic enzymes in hyperglycemia-induced testicular injury in type 2 diabetic rats
Ewere_2019_Mar.Environ.Res__104765 Imidacloprid and formulated product impacts the fatty acids and enzymatic activities in tissues of Sydney rock oysters, Saccostrea glomerata
Famurewa_2019_J.Food.Biochem_43_e12748 Moringa oleifera seed oil or virgin coconut oil supplementation abrogates cerebral neurotoxicity induced by antineoplastic agent methotrexate by suppression of oxidative stress and neuro-inflammation in rats
Giacconi_2019_J.Trace.Elem.Med.Biol_55_58 Acetylcholinesterase inhibitors in Alzheimer's disease influence Zinc and Copper homeostasis
Hou_2019_Drug.Alcohol.Depend_202_168 Evaluation of the cholinesterase activity of a potential therapeutic cocaine esterase for cocaine overdose
Huang_2019_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_224_117412 Colorimetric assay of acetylcholinesterase inhibitor tacrine based on MoO2 nanoparticles as peroxidase mimetics
Hwang_2019_Pharmaceutics_11_ Identification of Catalposide Metabolites in Human Liver and Intestinal Preparations and Characterization of the Relevant Sulfotransferase, UDP-glucuronosyltransferase, and Carboxylesterase Enzymes
Ibrahim_2019_Invert.Neurosci_19_7 Assessment of the molluscicidal impact of extracted chlorophyllin on some biochemical parameters in the nervous tissue and histological changes in Biomphalaria alexandrina and Lymnaea natalensis snails
Jabbari_2019_Int.J.Mol.Sci_20_ Ionizing Radiation Increases the Activity of Exosomal Secretory Pathway in MCF-7 Human Breast Cancer Cells: A Possible Way to Communicate Resistance against Radiotherapy
Jiang_2019_Fitoterapia__104277 Lycopodium alkaloids from Huperzia serrata
Kori_2019_J.Biochem.Mol.Toxicol__e22367 Cholinesterase inhibition and its association with hematological, biochemical and oxidative stress markers in chronic pesticide exposed agriculture workers
Li_2019_Molecules_24_2705 Bioactive Constituents of F. esculentum Bee Pollen and Quantitative Analysis of Samples Collected from Seven Areas by HPLC
Li_2019_Evid.Based.Complement.Alternat.Med_2019_5165029 Identification and Analysis of Chemical Constituents and Rat Serum Metabolites in Lycopodium clavatum Using UPLC-Q-TOF\/MS Combined with Multiple Data-Processing Approaches
Malomo_2019_J.Food.Biochem_43_e12897 Kinetics of acetylcholinesterase inhibition by hemp seed protein-derived peptides
McDermott_2019_Curr.Geriatr.Rep_8_1 Pharmacologic Management of Agitation in Patients with Dementia
Mochizuki_2019_Int.J.Mol.Sci_20_ Arsenic Neurotoxicity in Humans
Ojo_2019_J.Food.Biochem_43_e12772 Spondias mombim L. (Anacardiaceae): Chemical fingerprints, inhibitory activities, and molecular docking on key enzymes relevant to erectile dysfunction and Alzheimer's diseases
Olasehinde_2019_J.Food.Biochem_43_e12870 Aqueous-ethanol extracts of some South African seaweeds inhibit beta-amyloid aggregation, cholinesterases, and beta-secretase activities in vitro
Olasehinde_2019_Pharm.Biol_57_460 Phenolic composition, antioxidant activity, anticholinesterase potential and modulatory effects of aqueous extracts of some seaweeds on beta-amyloid aggregation and disaggregation
Pothu_2019_J.Family.Med.Prim.Care_8_2073 Evaluation of cholinesterase and lipid profile levels in chronic pesticide exposed persons
Reyna_2019_Sci.Total.Environ_692_175 A multilevel response approach reveals the Asian clam Corbicula largillierti as a mirror of aquatic pollution
Rodrigues_2019_Environ.Monit.Assess_191_503 Assessing the ecological status of fluvial ecosystems employing a macroinvertebrate multi-taxon and multi-biomarker approach
Safi_2019_Malar.J_18_249 Status of insecticide resistance and its biochemical and molecular mechanisms in Anopheles stephensi (Diptera: Culicidae) from Afghanistan
Saleem_2019_Antioxidants.(Basel)_8_ Bioassay Directed Isolation, Biological Evaluation and in Silico Studies of New Isolates from Pteris cretica L
Sohn_2019_Int.J.Mol.Sci_20_ Annona atemoya Leaf Extract Improves Scopolamine-Induced Memory Impairment by Preventing Hippocampal Cholinergic Dysfunction and Neuronal Cell Death
Yadav_2019_J.Food.Biochem_43_e12735 Inhibition of LPS induced neurochemical imbalance and oxidative stress by pigmented and non-pigmented rice bran extracts
Zhao_2019_Front.Cell.Neurosci_13_314 Down-Regulation of Essential Synaptic Components by GI-Tract Microbiome-Derived Lipopolysaccharide (LPS) in LPS-Treated Human Neuronal-Glial (HNG) Cells in Primary Culture: Relevance to Alzheimer's Disease (AD)
Abidar_2019_J.Food.Biochem__e13009 Glucose-mediated protein glycation: Contribution of methanolic extract of Ceratonia siliqua L. in protection and in vitro potential inhibition of acetylcholinesterase
Ahmad_2019_Nat.Prod.Res__1 Phenolic, flavonoid content and radical scavenging activity of Smilax China with its inhibitory potential against clinically important enzymes
Albishri_2019_Talanta_200_107 Hyphenation of enzyme\/graphene oxide-ionic liquid\/glassy carbon biosensors with anodic differential pulse stripping voltammetry for reliable determination of choline and acetylcholine in human serum
Baumann_2019_Molecules_24_ Synthesis and In Vitro Screening of Novel Heterocyclic beta-d-Gluco- and beta-d-Galactoconjugates as Butyrylcholinesterase Inhibitors
Boulajfene_2019_Environ.Monit.Assess_191_555 Biological and biochemical assessment in Phorcus articulatus (Lamarck 1822): contamination and seasonal effect
Briand_2019_Molecules_24_ Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1
Campigotto_2019_Exp.Parasitol__107735 Effects of oral administration of copper capsules on helminth control in lactating dairy sheep: An effective alternative to replace conventional antiparasitics during lactation
Chen_2019_Clin.Interv.Aging_14_1243 Different durations of cognitive stimulation therapy for Alzheimer's disease: a systematic review and meta-analysis
Choubdar_2019_Bioorg.Chem_91_103164 New classes of carbazoles as potential multi-functional anti-Alzheimer's agents
da Silva_2019_3.Biotech_9_38 Biocatalytic esterification of fatty acids using a low-cost fermented solid from solid-state fermentation with Yarrowia lipolytica
Dhanarisi_2019_Clin.Toxicol.(Phila)__1 A pilot clinical study of the neuromuscular blocker rocuronium to reduce the duration of ventilation after organophosphorus insecticide poisoning
Erdemir_2019_Bioorg.Chem_91_103134 Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties
Fabiani_2019_Front.Cell.Neurosci_13_309 Alzheimer's Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts
Faraone_2019_Plants.(Basel)_8_ Antioxidant, Antidiabetic, and Anticholinesterase Activities and Phytochemical Profile of Azorella glabra Wedd
Gniazdowska_2019_Bioorg.Chem_91_103136 Synthesis, physicochemical and biological evaluation of tacrine derivative labeled with technetium-99m and gallium-68 as a prospective diagnostic tool for early diagnosis of Alzheimer's disease
Ibrahim_2019_Pestic.Biochem.Physiol_159_127 Propolis relieves the cardiotoxicity of chlorpyrifos in diabetic rats via alleviations of paraoxonase-1 and xanthine oxidase genes expression
Jamshidi-Aidji_2019_J.Chromatogr.A__460366 Effect-directed screening of Bacillus lipopeptide extracts via hyphenated high-performance thin-layer chromatography
Janardhan_2019_Heliyon_5_e02163 Bungarus caeruleus venom neutralization activity of Azima tetracantha Lam. Extract
Jankowska_2019_Pestic.Biochem.Physiol_158_101 The unusual action of essential oil component, menthol, in potentiating the effect of the carbamate insecticide, bendiocarb
Khare_2019_Biomarkers__1 Glutathione Reductase and Catalase as Potential Biomarkers for Synergistic intoxication of Pesticides in fish
Liu_2019_Neurosci.Lett__134417 Structural and functional abnormalities of motor endplates in rat skeletal model of myofascial trigger spots
Lockridge_2019_Chem.Biol.Interact__108788 Half-life of chlorpyrifos oxon and other organophosphorus esters in aqueous solution
Lynn_2019_Biosci.Biotechnol.Biochem_83_892 (1)H Quantitative NMR analyses of beta-asarone and related compounds for quality control of Acorus rhizome herbal drugs in terms of the effects of their constituents on in vitro acetylcholine esterase activity
Mahran_2019_J.Chromatogr.A__460371 Effect-directed analysis by high-performance thin-layer chromatography for bioactive metabolites tracking in Primula veris flower and Primula boveana leaf extracts
Manco_2019_Chem.Biodivers_16_e1900318 Chemical Composition and Biological Activities of Metania and Drulia (Metaniidae) Freshwater Sponges from Amazonia
Miranda_2019_Int.J.Environ.Res.Public.Health_16_ Neurotoxicity, Behavior, and Lethal Effects of Cadmium, Microplastics, and Their Mixtures on Pomatoschistus microps Juveniles from Two Wild Populations Exposed under Laboratory Conditions-Implications to Environmental and Human Risk Assessment
Miyazaki_2019_Nihon.Ronen.Igakkai.Zasshi_56_301 [Possible relationship between prescription medications and urinary dysfunction in elderly home health care patients]
Modi_2019_Front.Psychiatry_10_513 Possible Implication of the CA2 Hippocampal Circuit in Social Cognition Deficits Observed in the Neuroligin 3 Knock-Out Mouse, a Non-Syndromic Animal Model of Autism
Mosbah_2019_J.Food.Biochem__e13012 Nutritional properties, identification of phenolic compounds, and enzyme inhibitory activities of Feijoa sellowiana leaves
Musoev_2019_Molecules_24_ Discovery of Novel DPP-IV Inhibitors as Potential Candidates for the Treatment of Type 2 Diabetes mellitus Predicted by 3D QSAR Pharmacophore Models, Molecular Docking and de novo Evolution
Nwanna_2019_J.Food.Biochem_43_e12910 Eggplant (Solanum spp) supplemented fruits diet modulated the activities of ectonucleoside triphosphate diphosphohydrolase (ENTPdase), monoamine oxidase (MAO), and cholinesterases (AChE\/BChE) in the brain of diabetic Wistar male rats
Othman_2019_Behav.Brain.Res_374_112122 Zinc improves clomipramine effects on depressive and locomotor behavior and reverses its oxidative stress in rats
Pinder_2019_Biomed.Pharmacother_118_109318 Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic\/pharmacodynamic study with population pharmacokinetic modeling
Shukla_2019_Physiol.Mol.Biol.Plants_25_1073 A proteomic study of cysteine protease induced cell death in anthers of male sterile tobacco transgenic plants
Tang_2019_Chem.Biol.Interact_297_67 Hydrophilic scaffolds of oxime as the potent catalytic inactivator of reactive organophosphate
Toublet_2019_Molecules_24_ Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease
Wong_2019_Ann.Clin.Transl.Neurol_6_1566 Donepezil increases resistance to induced seizures in a mouse model of Dravet syndrome
Yang_2019_Mikrochim.Acta_186_585 Carbon dots co-doped with nitrogen and chlorine for off-on fluorometric determination of the activity of acetylcholinesterase and for quantification of organophosphate pesticides
Yao_2019_Food.Chem_302_125199 Insights into the improvement of the enzymatic hydrolysis of bovine bone protein using lipase pretreatment
Zengin_2019_J.Food.Biochem__e13003 Chemical profiling and pharmaco-toxicological activity of Origanum sipyleum extracts: Exploring for novel sources for potential therapeutic agents
Abu-Farha_2019_Sci.Rep_9_11866 Reduced miR-181d level in obesity and its role in lipid metabolism via regulation of ANGPTL3
Bhatt_2019_Front.Microbiol_10_1778 Insight Into Microbial Applications for the Biodegradation of Pyrethroid Insecticides
Chauhan_2019_Arch.Pharm.(Weinheim)__e1900029 Design, synthesis, biological evaluation, and molecular modeling studies of rhodanine derivatives as pancreatic lipase inhibitors
Chen_2019_Int.J.Biol.Macromol_139_298 Two novel lipases purified from rice bran displaying lipolytic and esterification activities
Cohen_2019_Orphanet.J.Rare.Dis_14_198 Early diagnosis of infantile-onset lysosomal acid lipase deficiency in the advent of available enzyme replacement therapy
Daniel_2019_Int.J.Mol.Sci_20_ Differentially Expressed Mitochondrial Proteins in Human MCF7 Breast Cancer Cells Resistant to Paclitaxel
de Oliveira_2019_Int.J.Mol.Sci_20_ Synthesis of New Quinoline-Piperonal Hybrids as Potential Drugs against Alzheimer's Disease
Gupta_2019_Pharmacol.Res__104391 More than just an enzyme: Dipeptidyl peptidase-4 (DPP-4) and its association with diabetic kidney remodelling
Hindmarsh_2019_J.Palliat.Care__825859719869353 Administering Neostigmine as a Subcutaneous Infusion: A Case Report of a Patient Dying With Myasthenia Gravis
Kapka-Skrzypczak_2019_Mutat.Res_843_52 Assessment of DNA damage in Polish children environmentally exposed to pesticides
Karatas_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108606 The effects on brown trout (Salmo trutta fario) of different concentrations of deltamethrin
Korbelius_2019_Cell.Rep_28_1923 ATGL\/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes
Koseoglu_2019_World.J.Clin.Cases_7_1764 New treatment modalities in Alzheimer's disease
Lana_2019_Front.Mol.Neurosci_12_176 Homomeric and Heteromeric Abeta Species Exist in Human Brain and CSF Regardless of Alzheimer's Disease Status and Risk Genotype
Lee_2019_Crit.Rev.Food.Sci.Nutr__1 Production, safety, health effects and applications of diacylglycerol functional oil in food systems: a review
Li_2019_Molecules_24_2980 New Sesquiterpenoids from the Fermented Broth of Termitomyces albuminosus and their Anti-Acetylcholinesterase Activity
Li_2019_Front.Microbiol_10_1751 Pretreatment With Bacillus cereus Preserves Against D-Galactosamine-Induced Liver Injury in a Rat Model
Matsunaga_2019_J.Alzheimers.Dis_-1_1 Efficacy and Safety of Cholinesterase Inhibitors for Mild Cognitive Impairment:A Systematic Review and Meta-Analysis
Menden_2019_J.Enzyme.Inhib.Med.Chem_34_1474 A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activity
Patel_2019_Pharmacol.Biochem.Behav__172758 Rivastigmine does not alter cocaine-induced subjective effects or self-administration
Rawa_2019_J.Ethnopharmacol__112160 Anti-cholinesterase potential of diverse botanical families from Malaysia: Evaluation of crude extracts and fractions from liquid-liquid extraction and acid-base fractionation
Richter_2019_Neuroimage.Clin_24_101978 Spatial distributions of cholinergic impairment and neuronal hypometabolism differ in MCI due to AD
Saravanan_2019_J.Mol.Graph.Model_92_280 Exploring the different environments effect of piperine via combined crystallographic, QM\/MM and molecular dynamics simulation study
Shiau_2019_Sci.Rep_9_11974 Mechanism of Interleukin-4 Reducing Lipid Deposit by Regulating Hormone-Sensitive Lipase
Sinan_2019_Int.J.Environ.Health.Res__1 A comparative study of the HPLC-MS profiles and biological efficiency of different solvent leaf extracts of two African plants: Bersama abyssinica and Scoparia dulcis
Takada-Takatori_2019_Sci.Rep_9_11922 Donepezil modulates amyloid precursor protein endocytosis and reduction by up-regulation of SNX33 expression in primary cortical neurons
Tao_2019_Medicine.(Baltimore)_98_e16556 The effect on congenital heart diseases of maternal EPHX1 polymorphisms modified by polycyclic aromatic hydrocarbons exposure
Teratani_2019_Hepatol.Commun_3_1098 Lipoprotein Lipase Up-regulation in Hepatic Stellate Cells Exacerbates Liver Fibrosis in Nonalcoholic Steatohepatitis in Mice
Valadares_2019_Enzyme.Microb.Technol_130_109370 The secretome of two representative lignocellulose-decay basidiomycetes growing on sugarcane bagasse solid-state cultures
Wei_2019_PLoS.One_14_e0221090 Insecticidal effect of aconitine on the rice brown planthoppers
Wei_2019_Comput.Math.Methods.Med_2019_7239780 Noninvasive Evaluation of Liver Fibrosis Reverse Using Artificial Neural Network Model for Chronic Hepatitis B Patients
Xu_2019_Eur.J.Med.Chem_181_111598 Discovery of delta-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies
Zoubkova_2019_Front.Neurosci_13_771 Prenatal Exposure to Methamphetamine: Up-Regulation of Brain Receptor Genes
Abou_2019_Geriatr.Psychol.Neuropsychiatr.Vieil_17_317 Pharmacological management of delusions associated with dementia
Adefegha_2019_Drug.Chem.Toxicol__1 Thyme (Thymus vulgaris) leaf extract modulates purinergic and cholinergic enzyme activities in the brain homogenate of 5-fluorouracil administered rats
Appelt_2019_Comp.Immunol.Microbiol.Infect.Dis_66_101330 Cholinesterase as an inflammatory marker of subclinical infection of dairy cows infected by Neospora caninum and risk factors for disease
Aswathi_2019_Bioresour.Technol_292_122025 Rapid degradation of the organophosphate pesticide - Chlorpyrifos by a novel strain of Pseudomonas nitroreducens AR-3
Barbosa_2019_J.Ethnopharmacol_245_112183 Protective effects of Hydrocotyle umbellata var. bonariensis Lam. (Araliaceae) on memory in sleep-impaired female mice
Bentham_2019_Neural.Plast_2019_2305318 The Modulatory Effect of Cerebrovascular Burden in Response to Cognitive Stimulation in Healthy Ageing and Mild Cognitive Impairment
Bhartiya_2019_Cureus_11_e5438 Amitraz Poisoning: The not so (Un)common Poisoning
Boualia_2019_Arch.Pharm.(Weinheim)__e1900027 Synthesis, molecular docking studies, and biological evaluation of novel alkyl bis(4-amino-5-cyanopyrimidine) derivatives
Burry_2019_Cochrane.Database.Syst.Rev_9_CD011749 Pharmacological interventions for the treatment of delirium in critically ill adults
Caglayan_2019_J.Biochem.Mol.Toxicol__e22381 The effects of zingerone against vancomycin-induced lung, liver, kidney and testis toxicity in rats: The behavior of some metabolic enzymes
Carney_2019_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110321 Oxidative stress and biomarker responses in the Atlantic halibut after long term exposure to elevated CO2 and a range of temperatures
Carrarini_2019_Biomolecules_9_ A Stage-Based Approach to Therapy in Parkinson's Disease
Divya_2019_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_225_117477 Activity and thermal stability of Mycobacterium tuberculosis PE1 and PE2 proteins esterase domain in the presence of aprotic ionic liquids
Duggal_2019_J.Alzheimers.Dis.Rep_3_179 Neuroprotective Approach of Anti-Cancer Microtubule Stabilizers Against Tauopathy Associated Dementia: Current Status of Clinical and Preclinical Findings
Eddleston_2019_Clin.Toxicol.(Phila)__1 Efficacy of an organophosphorus hydrolase enzyme (OpdA) in human serum and minipig models of organophosphorus insecticide poisoning
Fujino_2019_Food.Chem.Toxicol_133_110792 Comparative study of the effect of 17 parabens on PXR-, CAR- and PPARalpha-mediated transcriptional activation
Guardia-Escote_2019_Behav.Brain.Res__112195 APOE genetic background and sex confer different vulnerabilities to postnatal chlorpyrifos exposure and modulate the response to cholinergic drugs
Gutti_2019_Eur.J.Med.Chem_182_111613 Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease
Hassan_2019_Bioorg.Chem_91_103138 Designing of promising medicinal scaffolds for Alzheimer's disease through enzyme inhibition, lead optimization, molecular docking and dynamic simulation approaches
Henrique_2019_Brain.Res__146408 Kaolin-induced hydrocephalus causes acetylcholinesterase activity dysfunction following hypothalamic damage in infant rats
Hira_2019_Biomolecules_9_ beta-Carotene: A Natural Compound Improves Cognitive Impairment and Oxidative Stress in a Mouse Model of Streptozotocin-Induced Alzheimer's Disease
Jeon_2019_Aging.Dis_10_307 Traditional Oriental Medicines and Alzheimer's Disease
Lan_2019_J.Mol.Graph.Model_93_107441 Prediction of AChE-ligand affinity using the umbrella sampling simulation
Lin_2019_Int.J.Nanomedicine_14_5817 Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity
Liu_2019_Phytomedicine__153077 Systematic exploration of Astragalus membranaceus and Panax ginseng as immune regulators: Insights from the comparative biological and computational analysis
Liu_2019_J.Biochem.Mol.Toxicol__e22391 ATGL promotes the proliferation of hepatocellular carcinoma cells via the p-AKT signaling pathway
Liu_2019_J.Chromatogr.A__460454 Capillary electrophoresis-immobilized enzyme microreactors for acetylcholinesterase assay with surface modification by highly-homogeneous microporous layer
Mahmoud_2019_Eur.J.Med.Chem_182_111651 Neurobehavioral investigation and acetylcholinesterase inhibitory activity study for some new coumarin derivatives
Mahmoudi_2019_Bioelectrochemistry_130_107348 High-performance electrochemical enzyme sensor for organophosphate pesticide detection using modified metal-organic framework sensing platforms
Mahran_2019_J.Chromatogr.A__460438 Guided isolation of new iridoid glucosides from Anarrhinum pubescens by high-performance thin-layer chromatography-acetylcholinesterase assay
Mandrioli_2019_Insect.Biochem.Mol.Biol_113_103228 Analysis of the extent of synteny and conservation in the gene order in aphids: A first glimpse from the Aphis glycines genome
Mathew_2019_Arch.Pharm.(Weinheim)__e1900177 Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases
Medina_2019_Sci.Rep_9_12318 Botryane terpenoids produced by Nemania bipapillata, an endophytic fungus isolated from red alga Asparagopsis taxiformis - Falkenbergia stage
Nos_2019_Chemosphere_238_124592 Tetrabromobisphenol A inhibits carboxylesterase activity of marine organisms from different trophic levels
Nowicka_2019_Antioxidants.(Basel)_8_ Anti-Hyperglycemic and Anticholinergic Effects of Natural Antioxidant Contents in Edible Flowers
Oh_2019_J.Psychiatr.Res_118_31 Effect of drug compliance on health care costs in newly-diagnosed dementia: Analysis of nationwide population-based data
Orlando_2019_Antioxidants.(Basel)_8_ Qualitative Chemical Characterization and Multidirectional Biological Investigation of Leaves and Bark Extracts of Anogeissus leiocarpus (DC.) Guill. & Perr. (Combretaceae)
Park_2019_Biology.(Basel)_8_ Transcriptome Analysis and Metabolic Profiling of Lycoris Radiata
Paudel_2019_ACS.Omega_4_6283 Arylbenzofurans from the Root Bark of Morus alba as Triple Inhibitors of Cholinesterase, beta-Site Amyloid Precursor Protein Cleaving Enzyme 1, and Glycogen Synthase Kinase-3beta: Relevance to Alzheimer's Disease
Paudel_2019_ACS.Omega_4_12259 Anti-Alzheimer's Disease Activity of Bromophenols from a Red Alga, Symphyocladia latiuscula (Harvey) Yamada
Polumackanycz_2019_Molecules_24_ A Comparative Study on the Phenolic Composition and Biological Activities of Morus alba L. Commercial Samples
Qian_2019_J.Clin.Psychopharmacol_39_462 The Potential for Pharmacokinetic Interactions Between Cannabis Products and Conventional Medications
Sahin_2019_J.Biomol.Struct.Dyn__1 Novel AChE and BChE Inhibitors Using Combined Virtual Screening, Text mining and In Vitro Binding Assays
Sakayanathan_2019_Int.J.Biol.Macromol_140_1147 In vitro and in silico analysis of novel astaxanthin-s-allyl cysteine as an inhibitor of butyrylcholinesterase and various globular forms of acetylcholinesterases
Sanchez-Hernandez_2019_Ecotoxicol.Environ.Saf_183_109586 Exploring the potential enzymatic bioremediation of vermicompost through pesticide-detoxifying carboxylesterases
Spector_2019_BMJ.Open_9_e030933 Mixed methods implementation research of cognitive stimulation therapy (CST) for dementia in low and middle-income countries: study protocol for Brazil, India and Tanzania (CST-International)
Sperling_2019_Brain.Res__146424 Galantamine improves functional recovery and reduces lesion size in a rat model of spinal cord injury
Svobodova_2019_Biomolecules_9_ Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors
Swartzwelder_2019_Sci.Rep_9_12110 Changes in Neuroimmune and Neuronal Death Markers after Adolescent Alcohol Exposure in Rats are Reversed by Donepezil
Taslimi_2019_Bioorg.Chem_92_103213 Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials
Thapa_2019_Mol.Biotechnol_61_579 Biochemical Characteristics of Microbial Enzymes and Their Significance from Industrial Perspectives
Topal_2019_J.Biochem.Mol.Toxicol__e22385 Inhibition profiles of Voriconazole against acetylcholinesterase, alpha-glycosidase, and human carbonic anhydrase I and II isoenzymes
Vafadarnejad_2019_Bioorg.Chem_92_103192 Novel N-benzylpyridinium moiety linked to arylisoxazole derivatives as selective butyrylcholinesterase inhibitors: Synthesis, biological evaluation, and docking study
Veno_2019_Molecules_24_ Insight into Improved Thermostability of Cold-Adapted Staphylococcal Lipase by Glycine to Cysteine Mutation
Villaecija-Aguilar_2019_PLoS.Genet_15_e1008327 SMAX1\/SMXL2 regulate root and root hair development downstream of KAI2-mediated signalling in Arabidopsis
Wu_2019_Iran.J.Biotechnol_17_e2189 Enhancement of Soluble Expression and Biochemical Characterization of Two Epoxide Hydrolases from Bacillus
Wu_2019_Small__e1903108 Oxidase-Like Fe-N-C Single-Atom Nanozymes for the Detection of Acetylcholinesterase Activity
Odendall_2019_Mol.Biol.Cell__mbcE19030166 The mitochondrial intermembrane space facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism
Ahmad_2019_Bioorg.Chem_92_103216 Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs
Bernardo_2019_Pharmacol.Biochem.Behav__172790 Cholinergic system and exploratory behavior are changed after weekly-binge ethanol exposure in zebrafish
Burgett_2019_BMJ.Case.Rep_12_ Acute treatment of psychotic symptoms in a newly diagnosed Lewy body dementia patient with an accelerated titration schedule of rivastigmine and de-escalation of antipsychotics
Chaves_2019_J.Inorg.Biochem_200_110800 In vitro tyrosinase, acetylcholinesterase, and HSA evaluation of dioxidovanadium (V) complexes: An experimental and theoretical approach
Contreras-Aguilar_2019_Res.Vet.Sci_126_155 Application of a score for evaluation of pain, distress and discomfort in pigs with lameness and prolapses: correlation with saliva biomarkers and severity of the disease
Deveci_2019_J.Food.Biochem_43_e12965 Structural characterization and determination of biological activities for different polysaccharides extracted from tree mushroom species
Garcia-Gracia_2019_Toxicol.Rep_6_862 Three (-)-cytisine derivatives and 1-hydroxyquinopimaric acid as acetylcholinesterase inhibitors
Hormigo_2019_Behav.Brain.Res__112077 Subchronic use of rivastigmine increases procognitive flexibility across multimodal behavioral tasks in healthy male rats
Huffaker_2019_JIMD.Rep_49_30 Case series of sebelipase alfa hypersensitivity reactions and successful sebelipase alfa rapid desensitization
Kariyanna_2019_Am.J.Med.Case.Rep_7_203 Defining Features of Patients who Develop Takotsubo Cardiomyopathy during Myasthenic Crisis: A Systematic Review of Case Studies
Klainbart_2019_Vet.J_251_105349 Clinical manifestations, laboratory findings, treatment and outcome of acute organophosphate or carbamate intoxication in 102 dogs: A retrospective study
Li_2019_Ann.Thorac.Surg_108_912 Results of Robotic Thymectomy Performed in Myasthenia Gravis Patients Older Than 60 Years at Onset
Warakanont_2019_Plant.Cell.Physiol_60_1250 LIP4 Is Involved in Triacylglycerol Degradation in Chlamydomonas reinhardtii
de Santana_2019_Nat.Commun_10_4000 Unexpected species diversity in electric eels with a description of the strongest living bioelectricity generator
Abdul_2019_Front.Aging.Neurosci_11_206 Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay
Ceylan_2019_J.Trace.Elem.Med.Biol_56_198 Examining the link between dose-dependent dietary iron intake and Alzheimer's disease through oxidative stress in the rat cortex
Dunn_2019_Pharmacol.Rev_71_503 Beyond the Ligand: Extracellular and Transcellular G Protein-Coupled Receptor Complexes in Physiology and Pharmacology
Edwards_2019_Sensors.(Basel)_19_ Peptide Nanotube Encapsulated Enzyme Biosensor for Vapor Phase Detection of Malathion, an Organophosphorus Compound
El Bishbishy_2019_J.Pharm.Biomed.Anal_177_112840 Chemometric discrimination of three Pistacia species via their metabolic profiling and their possible in vitro effects on memory functions
Guo_2019_Bioorg.Chem_92_103258 Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo
Hapca_2019_Alzheimers.Dement.(N.Y)_5_431 Are antidementia drugs associated with reduced mortality after a hospital emergency admission in the population with dementia aged 65 years and older?
Hu_2019_Anal.Chim.Acta_1085_91 Nanoporous gold electrode for ultrasensitive detection of neurotoxin fasciculin
Khairy_2019_Nutr.Neurosci__1 Protective effects of vitamin D on neurophysiologic alterations in brain aging: role of brain-derived neurotrophic factor (BDNF)
Li_2019_Pestic.Biochem.Physiol_160_136 Toxicity of Chimonanthus nitens flower extracts to the golden apple snail, Pomacea canaliculata
Lu_2019_Pestic.Biochem.Physiol_160_127 Copper exposure enhances Spodoptera litura larval tolerance to beta-cypermethrin
Mukhametgalieva_2019_Biochim.Biophys.Acta.Proteins.Proteom__140270 A new sensitive spectrofluorimetric method for measurement of activity and kinetic study of cholinesterases
Muniz-Gonzalez_2019_Sci.Total.Environ_698_134292 Combined effects of benzophenone-3 and temperature on gene expression and enzymatic activity in the aquatic larvae Chironomus riparius
Perez_2019_Acta.Neuropathol.Commun_7_147 The p75(NTR) neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability
Riva_2019_Pestic.Biochem.Physiol_160_11 In silico chemical library screening and experimental validation of novel compounds with potential varroacide activities
Sinclair_2019_Alzheimers.Res.Ther_11_80 Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to these areas
Stolakis_2019_J.Matern.Fetal.Neonatal.Med__1 Effects of gestational thiamine-deprivation and\/or exposure to ethanol on crucial offspring rat brain enzyme activities
Su_2019_PLoS.Negl.Trop.Dis_13_e0007665 Fast emerging insecticide resistance in Aedes albopictus in Guangzhou, China: Alarm to the dengue epidemic
Thanigaivel_2019_Pestic.Biochem.Physiol_160_163 Toxic effect of essential oil and its compounds isolated from Sphaeranthus amaranthoides Burm. f. against dengue mosquito vector Aedes aegypti Linn
Van Tassel_2019_Protein.Expr.Purif__105498 Efficient production of wild-type lipase B from Candida antarctica in the cytoplasm of Escherichia coli
Wang_2019_Int.J.Physiol.Pathophysiol.Pharmacol_11_115 Neurexin-1alpha regulates neurite growth of rat hippocampal neurons
Wang_2019_Basic.Res.Cardiol_114_41 Carotid baroreceptor stimulation suppresses ventricular fibrillation in canines with chronic heart failure
Zheng_2019_Bioorg.Med.Chem__115088 Synthesis and biological evaluation of calycanthaceous alkaloid analogs
Abdel-Diam_2019_Environ.Sci.Pollut.Res.Int_26_3659 Curcumin and quercetin synergistically attenuate subacute diazinon-induced inflammation and oxidative neurohepatic damage, and acetylcholinesterase inhibition in albino rats
Abdellaoui_2019_Neotrop.Entomol_48_246 Olive Leaf Extracts Toxicity to the Migratory Locust, Locusta migratoria: Histopathological Effects on the Alimentary Canal and Acetylcholinesterase and Glutathione S-Transferases Activity
Adedara_2019_Food.Chem.Toxicol_125_170 Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats
Ah_2019_Basic.Clin.Pharmacol.Toxicol_124_741 Effect of anticholinergic burden on treatment modification, delirium and mortality in newly diagnosed dementia patients starting a cholinesterase inhibitor: A population-based study
Ahmadi-Motamayel_2019_Spec.Care.Dentist_39_39 Evaluation of salivary acetylcholinesterase and pseudocholinesterase in patients with Alzheimer's disease: A case-control study
Ajayi_2019_J.Ethnopharmacol_231_503 Acetylcholinesterase inhibitor from Anthocleista vogelii leaf extracts
Alam_2019_Curr.Drug.Targets_20_316 Potential Enzymatic Targets in Alzheimer's: A Comprehensive Review
Ali_2019_Toxicol.Appl.Pharmacol_363_154 Bone loss in MPTP mouse model of Parkinson's disease is triggered by decreased osteoblastogenesis and increased osteoclastogenesis
Allan_2019_J.Lipid.Res_60_869 An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner
Bacalhau_2019_Bioorg.Med.Chem_27_354 In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor
Barai_2019_Behav.Brain.Res_356_18 Neuroprotective effects of bergenin in Alzheimer's disease: Investigation through molecular docking, in vitro and in vivo studies
Bartolini_2019_Chem.Rec_19_927 Tacrines as Therapeutic Agents for Alzheimer's Disease. IV. The Tacripyrines and Related Annulated Tacrines
Bemben_2019_Mol.Psychiatry_24_145 Isoform-specific cleavage of neuroligin-3 reduces synapse strength
Bermejo-Poza_2019_Fish.Physiol.Biochem_45_253 Physio-metabolic response of rainbow trout during prolonged food deprivation before slaughter
Bernacki_2019_Physiol.Plant_165_369 LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana
Bianchini_2019_Metallomics_11_362 Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicity
Biberoglu_2019_Chem.Biol.Interact_299_88 Azure B affects amyloid precursor protein metabolism in PS70cells
Bo_2019_Eur.J.Intern.Med_61_34 Prevalence, predictors and clinical implications of prolonged corrected QT in elderly patients with dementia and suspected syncope
Brewster_2019_ACS.Chem.Neurosci_10_155 Classics in Chemical Neuroscience: Donepezil
Brito_2019_Med.Vet.Entomol_33_121 Pyrethroid and organophosphate pesticide resistance in field populations of horn fly in Brazil
Butinof_2019_Gac.Sanit_33_216 [Biomonitoring in exposure to pesticides, its contribution to epidemiological surveillance of pesticide applicators in Cordoba, Argentina]
Capparelli_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_216_93 Seasonal environmental parameters influence biochemical responses of the fiddler crab Minuca rapax to contamination in situ
Chaubey_2019_Chem.Biol.Interact_298_66 Differential proteome analysis of rat plasma after diisopropyl fluorophosphate (DFP) intoxication, a surrogate of nerve agent sarin
Chaudhary_2019_J.Cell.Physiol_234_8019 Necrosis and necroptosis in germ cell depletion from mammalian ovary
Chen_2019_Int.J.Mol.Med_43_91 MicroRNA-98 reduces amyloid beta-protein production and improves oxidative stress and mitochondrial dysfunction through the Notch signaling pathway via HEY2 in Alzheimer's disease mice
Chen_2019_Analyst_144_559 Thiol-ene click reaction-induced fluorescence enhancement by altering the radiative rate for assaying butyrylcholinesterase activity
Chen_2019_J.Sep.Sci_42_650 Preparative separation of the flavonoid fractions from Periploca forrestii Schltr. ethanol extracts using macroporous resin combined with HPLC analysis and evaluation of their biological activities
Chmielewska_2019_Mol.Neurobiol_56_2741 Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage
Couselo-Seijas_2019_J.Cell.Physiol_234_10512 Cholinergic activity regulates the secretome of epicardial adipose tissue: Association with atrial fibrillation
da Rocha_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_218_30 Neurotoxicity in zebrafish exposed to carbon nanotubes: Effects on neurotransmitters levels and antioxidant system
Dai_2019_Anat.Sci.Int_94_128 The distribution of nerves supplying the testis, epididymis and accessory sex glands of Suncus murinus
Daniel_2019_Environ.Sci.Pollut.Res.Int_26_3320 Acute and chronic effects of paracetamol exposure on Daphnia magna: how oxidative effects may modulate responses at distinct levels of organization in a model species
Darreh-Shori_2019_Mol.Neurobiol_56_4601 Increased Active OMI\/HTRA2 Serine Protease Displays a Positive Correlation with Cholinergic Alterations in the Alzheimer's Disease Brain
de Abreu_2019_Neurosci.Lett_692_181 Effects of lidocaine on adult zebrafish behavior and brain acetylcholinesterase following peripheral and systemic administration
de Andrade_2019_Bioorg.Med.Chem_27_931 Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease
de Freitas Couto_2019_J.Trace.Elem.Med.Biol_54_232 7-chloro-4-(phenylselanyl) quinoline prevents dopamine depletion in a Drosophila melanogaster model of Parkinson's-like disease
Dimitriou_2019_Protein.Sci_28_344 Distinctive structural motifs co-ordinate the catalytic nucleophile and the residues of the oxyanion hole in the alpha\/beta-hydrolase fold enzymes
Eddleston_2019_Annu.Rev.Pharmacol.Toxicol_59_341 Novel Clinical Toxicology and Pharmacology of Organophosphorus Insecticide Self-Poisoning
Fernandes_2019_Neurotox.Res_35_150 The Antidiabetic Drug Liraglutide Minimizes the Non-Cholinergic Neurotoxicity of the Pesticide Mipafox in SH-SY5Y Cells
Ferrari_2019_Neurosci.Lett_694_74 Synaptic ATPases system of rat frontal cerebral cortex during aging
Feter_2019_Physiol.Behav_201_42 How does physical activity and different models of exercise training affect oxidative parameters and memory?
Filippatos_2019_Curr.Vasc.Pharmacol_17_332 Novel Hypolipidaemic Drugs: Mechanisms of Action and Main Metabolic Effects
Franjesevic_2019_Chemistry_25_5337 Resurrection and Reactivation of Acetylcholinesterase and Butyrylcholinesterase
Friedman_2019_Pharmacol.Ther_194_222 Acetylcholine signaling system in progression of lung cancers
Fujii_2019_Cancer.Chemother.Pharmacol_83_123 Dose adjustment of irinotecan based on UGT1A1 polymorphisms in patients with colorectal cancer
Gomes_2019_Med.Chem_15_373 Spirocyclohexadienones as an Uncommon Scaffold for Acetylcholinesterase Inhibitory Activity
Hadda_2019_Mini.Rev.Med.Chem_19_688 Drug Design of Inhibitors of Alzheimer's Disease (AD): POM and DFT Analyses of Cholinesterase Inhibitory Activity of beta-amino di-Carbonyl Derivatives
Haeri_2019_Anat.Sci.Int_94_119 Neuroprotective effect of crocin on substantia nigra in MPTP-induced Parkinson's disease model of mice
Hager_2019_Med.Klin.Intensivmed.Notfmed_114_463 [Tapering of antidementia drugs, antidepressants and antipsychotics in elderly patients : When possible, when not?]
Halbach_2019_Anal.Bioanal.Chem_411_617 Elemental imaging (LA-ICP-MS) of zebrafish embryos to study the toxicokinetics of the acetylcholinesterase inhibitor naled
Halmenschelager_2019_Biol.Trace.Elem.Res_189_574 Biochemical CuSO4 Toxicity in Drosophila melanogaster Depends on Sex and Developmental Stage of Exposure
Hamed_2019_Fish.Physiol.Biochem_45_71 Antioxidant activities of Moringa oleifera leaf extract against pendimethalin-induced oxidative stress and genotoxicity in Nile tilapia, Oreochromis niloticus (L.)
Harayashiki_2019_Mar.Environ.Res_144_62 Behavioural and brain biomarker responses in yellowfin bream (Acanthopagrus australis) after inorganic mercury ingestion
He_2019_Eur.J.Pharmacol_842_365 Tectochrysin from Alpinia Oxyphylla Miq. alleviates Abeta1-42 induced learning and memory impairments in mice
Hemmerich_2019_Biotechnol.Bioeng_116_644 Combinatorial impact of Sec signal peptides from Bacillus subtilis and bioprocess conditions on heterologous cutinase secretion by Corynebacterium glutamicum
Hennebelle_2019_J.Lipid.Res_60_671 Brain oxylipin concentrations following hypercapnia\/ischemia: effects of brain dissection and dissection time
Hong_2019_Chem.Biol.Drug.Des_93_188 Synthesis and biological evaluation of genistein-O-alkylamine derivatives as potential multifunctional anti-Alzheimer agents
Hu_2019_ACS.Chem.Neurosci_10_537 Design, Synthesis, and Biological Evaluation of Dual-Target Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 9A (PDE9A) for the Treatment of Alzheimer's Disease
Hu_2019_Brain.Pathol_29_502 Early growth response-1 regulates acetylcholinesterase and its relation with the course of Alzheimer's disease
Huang_2019_Semin.Arthritis.Rheum_48_745 Concurrent inflammatory myopathy and myasthenia gravis with or without thymic pathology: A case series and literature review
Huang_2019_Chem.Biol.Drug.Des_93_110 Design, synthesis, and evaluation of genipin derivatives for the treatment of Alzheimer's Disease
Jing_2019_Drug.Discov.Today_24_629 Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors
John_2019_Rapid.Commun.Mass.Spectrom_33_259 Collision-induced mass spectrometric fragmentation of protonated dimethoate and omethoate generated by electrospray ionization
Kant_2019_Brain.Res_1707_227 Evaluation of cholinergic functions in patients with Japanese encephalitis and Herpes simplex encephalitis
Khan_2019_Metab.Brain.Dis_34_87 Effect of Nelumbo nucifera fruit on scopolamine induced memory deficits and motor coordination
Kilic_2019_Med.Chem_15_59 Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Abeta-Aggregation Inhibitors
Kim_2019_Hum.Brain.Mapp_40_252 Aberrant structural-functional coupling in adult cannabis users
Kim_2019_Neuroimage_190_94 Compensatory dopaminergic-cholinergic interactions in conflict processing: Evidence from patients with Parkinson's disease
Kumar_2019_Curr.Alzheimer.Res_16_116 Computational and In-Vitro Validation of Natural Molecules as Potential Acetylcholinesterase Inhibitors and Neuroprotective Agents
Kumar_2019_ACS.Chem.Neurosci_10_252 4,6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer's Disease
Lee_2019_Mol.Neurobiol_56_2495 Genetic Deletion of Soluble Epoxide Hydroxylase Causes Anxiety-Like Behaviors in Mice
Liu_2019_Clin.Microbiol.Infect_25_514 e1 Gamma-glutamyl transpeptidase to cholinesterase and platelet ratio in predicting significant liver fibrosis and cirrhosis of chronic hepatitis B
Liu_2019_Parkinsonism.Relat.Disord_60_14 Pharmacological treatment of apathy in Lewy body disorders: A systematic review
Liu_2019_Insect.Sci_26_711 Exposure to herbicides reduces larval sensitivity to insecticides in Spodoptera litura (Lepidoptera: Noctuidae)
Liu_2019_J.Atheroscler.Thromb_26_136 A Compound Heterozygous Mutation of Lipase Maturation Factor 1 is Responsible for Hypertriglyceridemia of a Patient
Liu_2019_Anim.Sci.J_90_271 Effects of porcine brain hydrolysate on impairment of cognitive learning ability in amyloid beta(1-40) -infused rats
Lum_2019_Singapore.Med.J_60_154 Medication compliance in Singaporean patients with Alzheimer's disease
Luzeena_2019_Gen.Comp.Endocrinol_279_53 Transient exposure of methylparaben to zebrafish (Danio rerio) embryos altered cortisol level, acetylcholinesterase activity and induced anxiety-like behaviour
Ma_2019_Fish.Physiol.Biochem_45_199 Identification of Carassius auratus gibelio liver cell proteins interacting with the GABAA receptor gamma2 subunit using a yeast two-hybrid system
Mamdooh_2019_Drug.Dev.Res_80_310 Evaluation of selected commercial pharmacotherapeutic drugs as potential pancreatic lipase inhibitors and antiproliferative compounds
Mantri_2019_JAMA.Neurol_76_41 Patterns of Dementia Treatment and Frank Prescribing Errors in Older Adults With Parkinson Disease
Martinez-Morcillo_2019_Toxicol.In.Vitro_54_89 The organophosphorus pesticide dimethoate decreases cell viability and induces changes in different biochemical parameters of rat pancreatic stellate cells
Meltzer_2019_Behav.Brain.Res_361_139 The allosteric dopamine D1 receptor potentiator, DETQ, ameliorates subchronic phencyclidine-induced object recognition memory deficits and enhances cortical acetylcholine efflux in male humanized D1 receptor knock-in mice
Mendivil-Perez_2019_J.Neurosci.Methods_312_126 Direct transdifferentiation of human Wharton's jelly mesenchymal stromal cells into cholinergic-like neurons
Mkhinini_2019_Environ.Sci.Pollut.Res.Int_26_2851 Biochemical and transcriptomic response of earthworms Eisenia andrei exposed to soils irrigated with treated wastewater
Muller_2019_Eur.J.Anaesthesiol_36_114 Relevance of peripheral cholinesterase activity on postoperative delirium in adult surgical patients (CESARO): A prospective observational cohort study
Mustafa_2019_Int.Urol.Nephrol_51_73 Effect of pregnancy on the cholinergic responses of the bladder: role of acetylcholinesterase
Nair_2019_Neuropharmacol_146_74 The high efficacy of muscarinic M4 receptor in D1 medium spiny neurons reverses striatal hyperdopaminergia
Niimi_2019_Parkinsonism.Relat.Disord_61_132 Altered regulation of serum lysosomal acid hydrolase activities in Parkinson's disease: A potential peripheral biomarker?
Nishida_2019_Intern.Med_58_1003 Cerebellar Cognitive Affective Syndrome Improved by Donepezil
Nkpaa_2019_Biol.Trace.Elem.Res_191_135 Ethanol Exacerbates Manganese-Induced Neurobehavioral Deficits, Striatal Oxidative Stress, and Apoptosis Via Regulation of p53, Caspase-3, and Bax\/Bcl-2 Ratio-Dependent Pathway
Oh_2019_J.Proteomics_193_243 Venom proteome of Bungarus sindanus (Sind krait) from Pakistan and in vivo cross-neutralization of toxicity using an Indian polyvalent antivenom
Olabiyi_2019_Pathophysiology_26_61 Tetracarpidium conophorum Mull. Arg modulates sexual behaviour and biochemical parameters relevant to sexual function in male Wistar rats
Onaolapo_2019_J.Chem.Neuroanat_96_22 Subchronic ketamine alters behaviour, metabolic indices and brain morphology in adolescent rats: Involvement of oxidative stress, glutamate toxicity and caspase-3-mediated apoptosis
Panwar_2019_Endocr.Metab.Immune.Disord.Drug.Targets_19_449 Identification of Novel Pancreatic Lipase Inhibitors Using In Silico Studies
Parambi_2019_Cent.Nerv.Syst.Agents.Med.Chem_19_67 Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones
Park_2019_Biotechnol.Prog_35_e2744 Catalytic characteristics of a sn-1(3) regioselective lipase from Cordyceps militaris
Parlar_2019_Bioorg.Chem_87_888 Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones
Patel_2019_Environ.Sci.Pollut.Res.Int_26_91 Pesticides as the drivers of neuropsychotic diseases, cancers, and teratogenicity among agro-workers as well as general public
Patrick_2019_Pharmacotherapy_39_677 Drug Regimen Individualization for Attention-Deficit\/Hyperactivity Disorder: Guidance for Methylphenidate and Dexmethylphenidate Formulations
Przybylowska_2019_Curr.Neuropharmacol_17_472 Therapeutic Potential of Multifunctional Tacrine Analogues
Pu_2019_Int.J.Clin.Pharmacol.Ther_57_94 Donepezil decreases heart rate in elderly patients with Alzheimer's disease
Rane_2019_J.Hered_110_80 Detoxification Genes Differ Between Cactus-, Fruit-, and Flower-Feeding Drosophila
Rathish_2019_Environ.Sci.Pollut.Res.Int_26_2864 A low GLP-1 response among patients treated for acute organophosphate and carbamate poisoning: a comparative cross-sectional study from an agrarian region of Sri Lanka
Rodrigues_2019_Mol.Neurobiol_56_4945 Involvement of the Cholinergic Parameters and Glial Cells in Learning Delay Induced by Glutaric Acid: Protection by N-Acetylcysteine
Rodrigues_2019_Environ.Sci.Pollut.Res.Int_26_227 Toxicity of erythromycin to Oncorhynchus mykiss at different biochemical levels: detoxification metabolism, energetic balance, and neurological impairment
Rodriguez-Perez_2019_Phytochem.Anal_30_237 Chemical fingerprint and bioactivity evaluation of Globularia orientalis L. and Globularia trichosantha Fisch. & C. A. Mey. using non-targeted HPLC-ESI-QTOF-MS approach
Ruan_2019_Behav.Brain.Res_360_128 Cholinergic M4 receptors are involved in morphine-induced expression of behavioral sensitization by regulating dopamine function in the nucleus accumbens of rats
Saeedi_2019_Chem.Biodivers_16_e1800433 Design and Synthesis of Selective Acetylcholinesterase Inhibitors: Arylisoxazole-Phenylpiperazine Derivatives
Sako_2019_Neuropsychopharmacology_44_950 TAK-071, a novel M1 positive allosteric modulator with low cooperativity, improves cognitive function in rodents with few cholinergic side effects
Saleem_2019_Food.Chem.Toxicol_123_363 Biological, chemical and toxicological perspectives on aerial and roots of Filago germanica (L.) huds: Functional approaches for novel phyto-pharmaceuticals
Salek-Maghsoudi_2019_Toxicology_411_1 Biochemical and molecular evidence on the role of vaspin in early detection of the insulin resistance in a rat model of high-fat diet and use of diazinon
Schetinger_2019_Toxicology_411_154 Combined exposure to methylmercury and manganese during L1 larval stage causes motor dysfunction, cholinergic and monoaminergic up-regulation and oxidative stress in L4 Caenorhabditis elegans
Scullion_2019_Neurochem.Res_44_617 Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy
Seidel_2019_Biosens.Bioelectron_123_185 A multidimensional impedance platform for the real-time analysis of single and combination drug pharmacology in patient-derived viable melanoma models
Sethiya_2019_J.Ayurveda.Integr.Med_10_25 Neuropharmacological evaluation on four traditional herbs used as nervine tonic and commonly available as Shankhpushpi in India
Shao_2019_Psychosomatics_60_533 Is Lower Plasma Cholinesterase Activity Really a Candidate Biomarker for Postoperative Delirium After Noncardiac Surgery?
Sharath_2019_Pest.Manag.Sci_75_506 Enhancing RNAi by using concatemerized double-stranded RNA
Sharma_2019_Prog.Neurobiol_174_53 Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies
Shenhar-Tsarfaty_2019_Int.J.Obes.(Lond)_43_297 Obesity-related acetylcholinesterase elevation is reversed following laparoscopic sleeve gastrectomy
Singh_2019_Rejuvenation.Res_22_60 Rapamycin Confers Neuroprotection Against Aging-Induced Oxidative Stress, Mitochondrial Dysfunction, and Neurodegeneration in Old Rats Through Activation of Autophagy
Siqueira_2019_Neurotoxicol.Teratol_71_6 Atropine counteracts the depressive-like behaviour elicited by acute exposure to commercial chlorpyrifos in rats
Spinelli_2019_Chem.Biodivers_16_e1800472 Natural Multi-Target Inhibitors of Cholinesterases and Monoamine Oxidase Enzymes with Antioxidant Potential from Skin Extracts of Hypsiboas cordobae and Pseudis minuta (Anura: Hylidae)
Spohr_2019_Metab.Brain.Dis_34_605 Combined actions of blueberry extract and lithium on neurochemical changes observed in an experimental model of mania: exploiting possible synergistic effects
Stefanucci_2019_Future.Med.Chem_11_5 Discovery of arginine-containing tripeptides as a new class of pancreatic lipase inhibitors
Sun_2019_Metab.Brain.Dis_34_173 Neuroprotective effects of matrine on scopolamine-induced amnesia via inhibition of AChE\/BuChE and oxidative stress
Sun_2019_Minerva.Cardioangiol_67_246 The association of the S447X mutation in LPL with Coronary artery disease: a meta-analysis
Sun_2019_J.Cell.Mol.Med_23_887 Plasma levels of soluble ST2, but not IL-33, correlate with the severity of alcoholic liver disease
Sunena_2019_Curr.Drug.Deliv_16_51 Nose to Brain Delivery of Galantamine Loaded Nanoparticles: In-vivo Pharmacodynamic and Biochemical Study in Mice
Szurpnicka_2019_J.Ethnopharmacol_231_241 Therapeutic potential of mistletoe in CNS-related neurological disorders and the chemical composition of Viscum species
Tang_2019_Anal.Sci_35_401 Efficient Preservation of Acetylcholinesterase at Room Temperature for Facile Detection of Organophosphorus Pesticide
Tanhapour_2019_Mol.Biol.Rep_46_741 Association between activity and genotypes of paraoxonase1 L55M (rs854560) increases the disease activity of rheumatoid arthritis through oxidative stress
Thakur_2019_J.Ethnopharmacol_231_363 Potential of South African medicinal plants targeting the reduction of Abeta42 protein as a treatment of Alzheimer's disease
Umukoro_2019_Pathophysiology_26_77 Jobelyn(R) ameliorates neurological deficits in rats with ischemic stroke through inhibition of release of pro-inflammatory cytokines and NF-kappaB signaling pathway
Van Zandt_2019_Behav.Brain.Res_362_7 Adeno-associated viral overexpression of neuroligin 2 in the mouse hippocampus enhances GABAergic synapses and impairs hippocampal-dependent behaviors
Vartolomei_2019_Urol.Oncol_37_123 Role of serum cholinesterase in patients treated with salvage radical prostatectomy
Verlinden_2019_Brain.Behav.Immun_77_92 Innervation of the human spleen: A complete hilum-embedding approach
Vilcacundo_2019_J.Sci.Food.Agric_99_1225 Release of multifunctional peptides from kiwicha (Amaranthus caudatus) protein under in vitro gastrointestinal digestion
Wang_2019_Int.J.Mol.Med_43_956 Investigation of the neuroprotective effects of crocin via antioxidant activities in HT22 cells and in mice with Alzheimer's disease
Wang_2019_ACS.Chem.Neurosci_10_852 Reconsideration of Anticholinesterase Therapeutic Strategies against Alzheimer's Disease
Wang_2019_Eur.J.Pharmacol_846_63 Galantamine reversed early postoperative cognitive deficit via alleviating inflammation and enhancing synaptic transmission in mouse hippocampus
Wang_2019_Chemistry_25_1716 Heterogeneous Metal-Organic-Framework-Based Biohybrid Catalysts for Cascade Reactions in Organic Solvent
Xu_2019_Curr.Drug.Metab_20_130 Potential Pharmacokinetic Herb-Drug Interactions: Have we Overlooked the Importance of Human Carboxylesterases 1 and 2?
Xu_2019_Planta.Med_85_160 Infraspecific Variation of Huperzine A and B in Icelandic Huperzia selago Complex
Xu_2019_ACS.Chem.Neurosci_10_482 Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents
Yadav_2019_Inflammopharmacology_27_301 Targeting oxidative stress, acetylcholinesterase, proinflammatory cytokine, dopamine and GABA by eucalyptus oil (Eucalyptus globulus) to alleviate ketamine-induced psychosis in rats
Yang_2019_Asian-Australas.J.Anim.Sci_32_217 Effects of feed intake restriction during late pregnancy on the function, anti-oxidation capability and acute phase protein synthesis of ovine liver
Yang_2019_Phytochem.Anal_30_26 Screening and determination for potential acetylcholinesterase inhibitory constituents from ginseng stem-leaf saponins using ultrafiltration (UF)-LC-ESI-MS(2)
Yang_2019_Chin.J.Integr.Med_25_574 Effect and Safety of Huannao Yicong Formula () in Patients with Mild-to-Moderate Alzheimer's Disease: A Randomized, Double-Blinded, Donepezil-Controlled Trial
Yasuda_2019_Intern.Med_58_809 Sick Sinus Syndrome Observed in a Patient with Cholinesterase Deficiency
Yu_2019_Am.J.Emerg.Med_37_1611 Efficacy and outcomes of lipid resuscitation on organophosphate poisoning patients: A systematic review and meta-analysis
Yu_2019_Protein.Expr.Purif_154_98 Production of Phosphorylated Ric-8A proteins using protein kinase CK2
Zengin_2019_J.Pharm.Pharmacol_71_270 Chemical profile, antioxidant, and enzyme inhibitory properties of two Scutellaria species: S. orientalis L. and S. salviifolia Benth
Zengin_2019_Mol.Divers_23_625 Synthesis and anticholinesterase activity of novel non-hepatotoxic naphthyridine-11-amine derivatives
Zhang_2019_Anal.Bioanal.Chem_411_905 An ultrasensitive signal-on electrochemiluminescence biosensor based on Au nanoclusters for detecting acetylthiocholine
Zhao_2019_Psychosomatics_60_190 Low Plasma Cholinesterase Activity is Associated With Postoperative Delirium After Noncardiac Surgery in Elderly Patients: AProspective Observational Study
Zhao_2019_ACS.Chem.Neurosci_10_922 Implications of Successful Symptomatic Treatment in Parkinson's Disease for Therapeutic Strategies of Alzheimer's Disease
Zheng_2019_Int.J.Biol.Macromol_125_1016 An effective immobilized haloalkane dehalogenase DhaA from Rhodococcus rhodochrous by adsorption, crosslink and PEGylation on meso-cellular foam
Zhou_2019_J.Proteome.Res_18_1542 Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment
Zhu_2019_Environ.Sci.Technol_53_354 Biocatalytic Degradation of Parabens Mediated by Cell Surface Displayed Cutinase
Zhu_2019_Int.J.Colorectal.Dis_34_255 Optimal time for single-stage pull-through colectomy in infants with short-segment Hirschsprung disease
Abdshahzadeh_2019_Chem.Biodivers_16_e1800436 3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease
Adessi_2019_Chem.Biodivers_16_e1800662 Clinanthus microstephium, an Amaryllidaceae Species with Cholinesterase Inhibitor Alkaloids: Structure-Activity Analysis of Haemanthamine Skeleton Derivatives
Ahmed_2019_Drugs.Aging_36_589 Current Agents in Development for Treating Behavioral and Psychological Symptoms Associated with Dementia
Akinrinde_2019_Neurotoxicol_74_252 Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats
Alali_2019_Chemistry_25_11892 HFIP-Functionalized Co3 O4 Micro-Nano-Octahedra\/rGO as a Double-Layer Sensing Material for Chemical Warfare Agents
Ali_2019_Chem.Biol.Interact_309_108707 Flavanone glycosides inhibit beta-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Abeta aggregation in the amyloidogenic pathway
Almeida_2019_Environ.Sci.Pollut.Res.Int_26_9823 Effects of acetaminophen in oxidative stress and neurotoxicity biomarkers of the gastropod Phorcus lineatus
Almenares-Lopez_2019_Chem.Biol.Interact_13ChEPon_308_252 Copper(II)-dependent hydrolysis of trichloronate by turkey serum albumin
Alzu'bi_2019_Cereb.Cortex_29_1706 Thalamocortical Afferents Innervate the Cortical Subplate much Earlier in Development in Primate than in Rodent
Amara_2019_Environ.Sci.Pollut.Res.Int_26_7540 Di (2-ethylhexyl) phthalate induces cardiac disorders in BALB\/c mice
Amelia-Yap_2019_J.Med.Entomol_56_811 Pyrethroids Use: Threats on Metabolic-Mediated Resistance Mechanisms in the Primary Dengue Vector Aedes aegypti (Diptera: Culicidae)
Amend_2019_Toxicol.Lett_308_1 The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - A proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM)
Anderluh_2019_Pharmacol.Ther_201_1 DPP-4 inhibition: capital A, Cyrillic novel therapeutic approach to the treatment of pulmonary hypertension?
Andersson_2019_Anaesthesia_74_518 Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review
Anjum_2019_Environ.Sci.Pollut.Res.Int_26_6378 Butyrylcholinesterase-a potential plasma biomarker in manganese-induced neurobehavioral changes
Arens_2019_J.Med.Toxicol_15_184 Adverse Effects of Physostigmine
Aroniadou-Anderjaska_2019_Neurobiol.Dis__104406 Targeting the glutamatergic system to counteract organophosphate poisoning: A novel therapeutic strategy
Arumugam_2019_Bioorg.Med.Chem_27_2621 Dispiropyrrolidinyl-piperidone embedded indeno[1,2-b]quinoxaline heterocyclic hybrids: Synthesis, cholinesterase inhibitory activity and their molecular docking simulation
Azadniya_2019_J.Chromatogr.A_1602_458 Automated piezoelectric spraying of biological and enzymatic assays for effect-directed analysis of planar chromatograms
Bajgar_2019_Mini.Rev.Med.Chem_19_970 Some Possibilities to Study New Prophylactics against Nerve Agents
Bampi_2019_Pharmacol.Biochem.Behav_183_46 Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice
Banaee_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_222_145 Acute exposure to chlorpyrifos and glyphosate induces changes in hemolymph biochemical parameters in the crayfish, Astacus leptodactylus (Eschscholtz, 1823)
Barth_2019_Mol.Neurobiol_56_6398 7-Chloro-4-(Phenylselanyl) Quinoline with Memory Enhancer Action in Aging Rats: Modulation of Neuroplasticity, Acetylcholinesterase Activity, and Cholesterol Levels
Basaure_2019_Arch.Toxicol_93_693 Learning, memory and the expression of cholinergic components in mice are modulated by the pesticide chlorpyrifos depending upon age at exposure and apolipoprotein E (APOE) genotype
Bashir_2019_Drug.Dev.Res_80_595 Synthesis, characterization, molecular docking evaluation, antidepressant, and anti-Alzheimer effects of dibenzylidene ketone derivatives
Batalhao_2019_Fish.Physiol.Biochem_45_1377 Effects of methylphenidate on the aggressive behavior, serotonin and dopamine levels, and dopamine-related gene transcription in brain of male Nile tilapia (Oreochromis niloticus)
Bay_2019_Nano.Lett_19_2620 Hydrogel Gate Graphene Field-Effect Transistors as Multiplexed Biosensors
Bazzari_2019_Curr.Alzheimer.Res_16_261 Pharmacological Interventions to Attenuate Alzheimer's Disease Progression: The Story So Far
Belgrad_2019_Glia_67_2107 Oligodendrocyte involvement in Gulf War Illness
Bennett_2019_J.Pharmacol.Exp.Ther_369_182 Acetylcholine Inhibits Platelet Activation
Bhatia_2019_Curr.Neurovasc.Res_16_27 Ameliorative Effect of Phosphodiesterase-5 Inhibitor in Rat Model of Vascular Dementia
Biederman_2019_J.Comp.Physiol.B_189_213 Physical, chemical, and functional properties of neuronal membranes vary between species of Antarctic notothenioids differing in thermal tolerance
Binda_2019_Biochem.J_476_293 Sorting nexin 27 rescues neuroligin 2 from lysosomal degradation to control inhibitory synapse number
Binh_2019_Biochem.Biophys.Res.Commun_516_451 Dysfunction of LSD-1 induces JNK signaling pathway-dependent abnormal development of thorax and apoptosis cell death in Drosophila melanogaster
Bloch-Shilderman_2019_Arch.Toxicol_93_1365 Repetitive antidotal treatment is crucial in eliminating eye pathology, respiratory toxicity and death following whole-body VX vapor exposure in freely moving rats
Bohnen_2019_Ann.Neurol_85_538 Cholinergic system changes of falls and freezing of gait in Parkinson's disease
Bosak_2019_Chem.Biol.Interact_13ChEPon_308_101 Structural aspects of 4-aminoquinolines as reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase
Bouley_2019_Biochemistry_58_1709 Structural Basis of Lysosomal Phospholipase A2 Inhibition by Zn(2)
Braid_2019_Chem.Biol.Interact_305_66 Human umbilical cord perivascular cells: A novel source of the organophosphate antidote butyrylcholinesterase
Brodkorb_2019_Nat.Protoc_14_991 INFOGEST static in vitro simulation of gastrointestinal food digestion
Bugata_2019_J.Appl.Toxicol_39_702 Acute and subacute oral toxicity of copper oxide nanoparticles in female albino Wistar rats
Buldurun_2019_Chem.Biodivers_16_e1900243 Spectroscopic and Structural Characterization, Enzyme Inhibitions, and Antioxidant Effects of New Ru(II) and Ni(II) Complexes of Schiff Base
Cadenas_2019_Int.J.Cancer_145_901 LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer
Caglayan_2019_Environ.Sci.Pollut.Res.Int_26_26664 The effects of naringin on different cyclophosphamide-induced organ toxicities in rats: investigation of changes in some metabolic enzyme activities
Cai_2019_Ann.N.Y.Acad.Sci_1452_18 Myasthenia gravis and specific immunotherapy: monoclonal antibodies
Calderon_2019_J.Assist.Reprod.Genet_36_777 Morbid obesity-related changes in the expression of lipid receptors, transporters, and HSL in human sperm
Cappuccio_2019_J.Inherit.Metab.Dis_42_509 Opening a window on lysosomal acid lipase deficiency: Biochemical, molecular, and epidemiological insights
Carmo_2019_Environ.Toxicol_34_457 Overview of the toxic effects of titanium dioxide nanoparticles in blood, liver, muscles, and brain of a Neotropical detritivorous fish
Carroll_2019_Am.J.Addict_28_238 Double-Blind Placebo-Controlled Trial of Galantamine for Methadone-Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use
Castelli_2019_Exp.Parasitol_198_39 Exosome secretion by Leishmania infantum modulate the chemotactic behavior and cytokinic expression creating an environment permissive for early infection
Castillo-Morales_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_221_29 Mitochondrial affectation, DNA damage and AChE inhibition induced by Salvia officinalis essential oil on Aedes aegypti larvae
Cermeno_2019_Food.Funct_10_3421 Peptide identification from a Porphyra dioica protein hydrolysate with antioxidant, angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory activities
Chang_2019_Adv.Ther_36_1455 A 48-Week, Multicenter, Open-Label, Observational Study Evaluating Oral Rivastigmine in Patients with Mild-to-Moderate Alzheimer's Disease in Taiwan
Chang_2019_Curr.Opin.Clin.Nutr.Metab.Care_22_111 Lipoprotein lipase: new roles for an 'old' enzyme
Chatonnet_2019_Chem.Biol.Interact_13ChEPon_308_179 An evolutionary perspective on the first disulfide bond in members of the cholinesterase-carboxylesterase (COesterase) family: Possible outcomes for cholinesterase expression in prokaryotes
Chaves_2019_Free.Radic.Biol.Med_141_34 Impaired antioxidant capacity causes a disruption of metabolic homeostasis in sickle erythrocytes
Chellappandian_2019_Environ.Sci.Pollut.Res.Int_26_16303 Target and non-target botanical pesticides effect of Trichodesma indicum (Linn) R. Br. and their chemical derivatives against the dengue vector, Aedes aegypti L
Chen_2019_Int.J.Biol.Macromol_127_555 Protection effect of polyols on Rhizopus chinensis lipase counteracting the deactivation from high pressure and high temperature treatment
Chen_2019_Mol.Med.Rep_20_1085 Significant association between GPR50 hypomethylation and AD in males
Chen_2019_Mol.Divers_23_709 Hybrids of oxoisoaporphine-tetrahydroisoquinoline: novel multi-target inhibitors of inflammation and amyloid-beta aggregation in Alzheimer's disease
Chen_2019_ACS.Nano_13_7209 Cell-Membrane-Cloaked Oil Nanosponges Enable Dual-Modal Detoxification
Cheng_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_221_89 Bioaccumulation and toxicity of methoxychlor on Chinese mitten crab (Eriocheir sinensis)
Cheng_2019_ACS.Chem.Neurosci_10_3500 Tacrine-Hydrogen Sulfide Donor Hybrid Ameliorates Cognitive Impairment in the Aluminum Chloride Mouse Model of Alzheimer's Disease
Chiu_2019_Neurochem.Int_125_175 Novel compound VB-037 inhibits Abeta aggregation and promotes neurite outgrowth through enhancement of HSP27 and reduction of P38 and JNK-mediated inflammation in cell models for Alzheimer's disease
Chowdhary_2019_Biochimie_160_100 A novel fluorescence based assay for the detection of organophosphorus pesticide exposed cholinesterase activity using 1-naphthyl acetate
Craveur_2019_Amino.Acids_51_1065 Investigation of the impact of PTMs on the protein backbone conformation
Crews_2019_Alcohol.Clin.Exp.Res_43_1806 Mechanisms of Persistent Neurobiological Changes Following Adolescent Alcohol Exposure: NADIA Consortium Findings
Cummings_2019_J.Alzheimers.Dis_67_779 Treatment Combinations for Alzheimer's Disease: Current and Future Pharmacotherapy Options
da Silva Toscano Saes _2019_Bull.Environ.Contam.Toxicol_102_310 Sub-lethal Responses of the Polychaete Armandia agilis in Whole-sediment Toxicity Testing
Dai_2019_Neuron_102_993 Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses
Dail_2019_Toxicol.Sci_169_465 Novel Brain-Penetrating Oxime Acetylcholinesterase Reactivators Attenuate Organophosphate-Induced Neuropathology in the Rat Hippocampus
Dalal_2019_J.Mol.Biol_431_3107 Repurposing an Ancient Protein Core Structure: Structural Studies on FmtA, a Novel Esterase of Staphylococcus aureus
de Carvalho_2019_Brain.Res.Bull_149_60 Proconvulsant effects of sildenafil citrate on pilocarpine-induced seizures: Involvement of cholinergic, nitrergic and pro-oxidant mechanisms
de Castro_2019_Expert.Rev.Neurother_19_375 Non-conventional compounds with potential therapeutic effects against Alzheimer's disease
de la Luz Cadiz-Gurrea_2019_J.Sci.Food.Agric_99_6001 Innovative perspectives on Pulicaria dysenterica extracts: phyto-pharmaceutical properties, chemical characterization and multivariate analysis
Diaz-Resendiz_2019_Fish.Shellfish.Immunol_89_12 Effect of diazinon, an organophosphate pesticide, on signal transduction and death induction in mononuclear cells of Nile tilapia fish (Oreochromis niloticus)
DiFrancesco_2019_Neurol.Sci_40_2155 Generation and validation of algorithms to identify subjects with dementia using administrative data
Ding_2019_Toxicol.Lett_314_124 Understanding the bioconjugation reaction of phenthoate with human serum albumin: New insights from experimental and computational approaches
Ding_2019_J.Appl.Microbiol_127_985 Characterization and identification of ferulic acid esterase-producing Lactobacillus species isolated from Elymus nutans silage and their application in ensiled alfalfa
Djaoudene_2019_Food.Funct_10_4953 Phoenix dactylifera L. seeds: a by-product as a source of bioactive compounds with antioxidant and enzyme inhibitory properties
Dos Santos_2019_Food.Funct_10_573 The nanoencapsulation of curcuminoids extracted from Curcuma longa L. and an evaluation of their cytotoxic, enzymatic, antioxidant and anti-inflammatory activities
Duarte_2019_Mar.Environ.Res_147_24 Biomarker and behavioural responses of an estuarine fish following acute exposure to fluoxetine
Dusl_2019_J.Neurol_266_1107 Congenital myasthenic syndrome caused by novel COL13A1 mutations
Endo_2019_J.Nat.Med_73_648 Two new alkaloids from Crinum asiaticum var. japonicum
Eom_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_222_125 Effects of sublethal concentrations of the antifouling biocide Sea-Nine on biochemical parameters of the marine polychaete Perinereis aibuhitensis
Erukainure_2019_Metab.Brain.Dis_34_1385 Type 2 diabetes induced oxidative brain injury involves altered cerebellar neuronal integrity and elemental distribution, and exacerbated Nrf2 expression: therapeutic potential of raffia palm (Raphia hookeri) wine
Erukainure_2019_J.Ethnopharmacol_237_159 Raffia palm (Raphia hookeri G. Mann & H. Wendl) wine modulates glucose homeostasis by enhancing insulin secretion and inhibiting redox imbalance in a rat model of diabetes induced by high fructose diet and streptozotocin
Eruygur_2019_Mol.Biol.Rep_46_2121 In vitro antioxidant assessment, screening of enzyme inhibitory activities of methanol and water extracts and gene expression in Hypericum lydium
Es Ruiz de Arcaute_2019_Environ.Sci.Pollut.Res.Int_26_20485 Auxinic herbicides induce oxidative stress on Cnesterodon decemmaculatus (Pisces: Poeciliidae)
Eshetie_2019_Geriatr.Gerontol.Int_19_654 Potentially inappropriate prescribing before and after initiation of medicines for dementia: An Australian population-based study
Eshetie_2019_Int.J.Geriatr.Psychiatry_34_1498 Potentially inappropriate prescribing in people with dementia: An Australian population-based study
Essawy_2019_Environ.Sci.Pollut.Res.Int_26_26060 Soybean isoflavone ameliorates cognitive impairment, neuroinflammation, and amyloid beta accumulation in a rat model of Alzheimer's disease
Evoli_2019_Neurol.Sci_40_1111 Italian recommendations for the diagnosis and treatment of myasthenia gravis
Faghih_2019_Am.J.Gastroenterol_114_863 Pancreatic Lipase Variants and Risk of Pancreatitis: Clear or Unclear Pathogenicity?
Fang_2019_Cell.Cycle_18_1001 NF-kappaB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage
Filho_2019_Appl.Microbiol.Biotechnol_103_7399 Lipases: sources, immobilization methods, and industrial applications
Fiore_2019_Endocr.Metab.Immune.Disord.Drug.Targets_19_571 Focus on the Correlations between Alzheimer's Disease and Type 2 Diabetes
Fisher_2019_Pharmacoepidemiol.Drug.Saf_28_1067 Policy-induced selection bias in pharmacoepidemiology: The example of coverage for Alzheimer's medications in British Columbia
Formagio_2019_Inflammation_42_1561 Psychotria leiocarpa Extract and Vincosamide Reduce Chemically-Induced Inflammation in Mice and Inhibit the Acetylcholinesterase Activity
Fukuda_2019_Psychopharmacology.(Berl)_236_2847 Matured hop bitter acids improve spatial working and object recognition memory via nicotinic acetylcholine receptors
Furst_2019_Vox.Sang_114_275 Gender, cholinesterase, platelet count and red cell count are main predictors of peripheral blood stem cell mobilization in healthy donors
Ganeshpurkar_2019_Curr.Top.Med.Chem_19_501 Protein-Protein Interactions and Aggregation Inhibitors in Alzheimer's Disease
Gao_2019_Drug.Dev.Res_80_438 Structure-activity study of fluorine or chlorine-substituted cinnamic acid derivatives with tertiary amine side chain in acetylcholinesterase and butyrylcholinesterase inhibition
Garabadu_2019_Neurotox.Res_35_848 Eugenol Attenuates Scopolamine-Induced Hippocampal Cholinergic, Glutamatergic, and Mitochondrial Toxicity in Experimental Rats
Gargouri_2019_Behav.Brain.Res_370_111898 Repeated bifenthrin exposure alters hippocampal Nurr-1\/AChE and induces depression-like behavior in adult rats
Ge_2019_Chem.Commun.(Camb)_55_4945 A laser-induced TiO2-decorated graphene photoelectrode for sensitive photoelectrochemical biosensing
Geiss_2019_Physiol.Behav_204_121 Oral administration of lutein attenuates ethanol-induced memory deficit in rats by restoration of acetylcholinesterase activity
Ghosh_2019_Phys.Chem.Chem.Phys_21_13578 Revealing the mechanistic pathway of cholinergic inhibition of Alzheimer's disease by donepezil: a metadynamics simulation study
Ghribi_2019_Arch.Environ.Contam.Toxicol_76_678 Toxicity Assessment of Impacted Sediments from Southeast Coast of Tunisia Using a Biomarker Approach with the Polychaete Hediste diversicolor
Gimenez_2019_Environ.Sci.Pollut.Res.Int_26_21858 Effects of commonly used therapeutic drugs, paracetamol, and acetylsalicylic acid, on key physiological traits of the sea snail Gibbula umbilicalis
Godoy-Reyes_2019_Chem.Commun.(Camb)_55_5785 Acetylcholine-responsive cargo release using acetylcholinesterase-capped nanomaterials
Gore_2019_Toxicol.Lett_314_153 Ocular surface histopathological insult following sarin and VX exposure and potential treatments in the rat model
Grasing_2019_Behav.Pharmacol_30_478 The muscarinic agonist pilocarpine modifies cocaine-reinforced and food-reinforced responding in rats: comparison with the cholinesterase inhibitor tacrine
Griss_2019_Parasitol.Int_71_11 Oxidative stress linked to changes of cholinesterase and adenosine deaminase activities in experimentally infected chicken chicks with Eimeria spp
Grossberg_2019_J.Alzheimers.Dis_67_1157 Present Algorithms and Future Treatments for Alzheimer's Disease
Guillamat_2019_Thromb.Haemost_119_348 Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner
Gunbey_2019_Neuromuscul.Disord_29_290 Cardiac autonomic function evaluation in pediatric and adult patients with congenital myasthenic syndromes
Haghparast_2019_Peptides_117_170091 Apelin-13 attenuates motor impairments and prevents the changes in synaptic plasticity-related molecules in the striatum of Parkinsonism rats
Hamdi_2019_Environ.Sci.Pollut.Res.Int_26_17535 Oxidative stress, genotoxicity, biochemical and histopathological modifications induced by epoxiconazole in liver and kidney of Wistar rats
Han_2019_Alzheimer.Dis.Assoc.Disord_33_87 Cholinesterase Inhibitors May Not Benefit Mild Cognitive Impairment and Mild Alzheimer Disease Dementia
Han_2019_Nanoscale_11_14793 Single-particle enumeration-based ultrasensitive enzyme activity quantification with fluorescent polymer nanoparticles
He_2019_J.Proteomics_200_51 Label-free absolute protein quantification with data-independent acquisition
Hershey_2019_Drugs.Aging_36_309 Pharmacological Management of Dementia with Lewy Bodies
Hoffman_2019_Neuropharmacol_155_113 Retrograde activation of CB1R by muscarinic receptors protects against central organophosphorus toxicity
Hong_2019_J.Biotechnol_304_10 High-level expression of Humicola insolens cutinase in Pichia pastoris without carbon starvation and its use in cotton fabric bioscouring
Hosseini_2019_Bioorg.Med.Chem_27_2914 Design, synthesis, and biological evaluation of novel 4-oxobenzo[d]1,2,3-triazin-benzylpyridinum derivatives as potent anti-Alzheimer agents
Huang_2019_Bioorg.Med.Chem_27_644 Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors
Huang_2019_Analyst_144_3436 A sensitive fluorescence assay of organophosphorus pesticides using acetylcholinesterase and copper-catalyzed click chemistry
Huisa_2019_J.Alzheimers.Dis_67_707 Memantine and Acetylcholinesterase Inhibitor Use in Alzheimer's Disease Clinical Trials: Potential for Confounding by Indication
Hulse_2019_Br.J.Anaesth_123_457 Organophosphorus nerve agent poisoning: managing the poisoned patient
Huo_2019_Biochim.Biophys.Acta.Mol.Basis.Dis_1865_1226 Downregulated lncRNA-MIAT confers protection against erectile dysfunction by downregulating lipoprotein lipase via activation of miR-328a-5p in diabetic rats
Iha_2019_Neurotox.Res_35_575 Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor
Ishii_2019_Esophagus_16_408 Changes in the nutritional status of elderly patients after esophagectomy
Ishola_2019_Metab.Brain.Dis_34_979 Cortico-hippocampal memory enhancing activity of hesperetin on scopolamine-induced amnesia in mice: role of antioxidant defense system, cholinergic neurotransmission and expression of BDNF
Ishola_2019_Brain.Res_1712_188 Isorhamnetin enhanced cortico-hippocampal learning and memory capability in mice with scopolamine-induced amnesia: Role of antioxidant defense, cholinergic and BDNF signaling
Isik_2019_Neurochem.Res_44_2147 The Binding Mechanisms and Inhibitory Effect of Intravenous Anesthetics on AChE In Vitro and In Vivo: Kinetic Analysis and Molecular Docking
Islam_2019_J.Am.Med.Dir.Assoc_20_131 Personality Changes With Dementia From the Informant Perspective: New Data and Meta-Analysis
Iyengar_2019_Protein.Pept.Lett_26_471 Is Human Paraoxonase 1 the Saviour Against the Persistent Threat of Organophosphorus Nerve Agents?
Jackson_2019_J.Pharmacol.Toxicol.Methods_97_1 Validating a model of benzodiazepine refractory nerve agent-induced status epilepticus by evaluating the anticonvulsant and neuroprotective effects of scopolamine, memantine, and phenobarbital
Jamali-Raeufy_2019_Metab.Brain.Dis_34_1505 Troxerutin exerts neuroprotection against lipopolysaccharide (LPS) induced oxidative stress and neuroinflammation through targeting SIRT1\/SIRT3 signaling pathway
Javed_2019_Chem.Biol.Interact_13ChEPon_308_130 Association of status of acetylcholinesterase and ACHE gene 3' UTR variants (rs17228602, rs17228616) with drug addiction vulnerability in pakistani population
Jean_2019_J.Biol.Chem_294_6253 In vivo localization of human acetylcholinesterase-derived species in a beta-sheet conformation at the core of senile plaques in Alzheimer's disease
Jeong_2019_Bioorg.Med.Chem.Lett_29_2079 A new approach to procyanidins synthesis with potent anti-adipogenic effects
Jia_2019_Chem.Pharm.Bull.(Tokyo)_67_795 A Probe for Fluorescence Detection of the Acetylcholinesterase Activity Based on Molecularly Imprinted Polymers Coated Carbon Dots
Jiang_2019_J.Comput.Aided.Mol.Des_33_521 Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation
Jiang_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_220_1 Biomarkers responses in Manila clam, Ruditapes philippinarum after single and combined exposure to mercury and benzo[a]pyrene
Jin_2019_ACS.Appl.Mater.Interfaces_11_27605 Integrating Target-Responsive Hydrogels with Smartphone for On-Site ppb-Level Quantitation of Organophosphate Pesticides
John_2019_Life.Sci_228_98 Oxidative and histopathological alterations after sub-acute exposure of diisopropyl phosphorofluoridate in mice: Beneficial effect of Nacetylcysteine
Kala_2019_Physiol.Res_68_589 Sex-linked differences in the mortality in Ren-2 transgenic hypertensive rats with aorto-caval fistula: effects of treatment with angiotensin converting enzyme alone and combined with inhibitor of soluble epoxide hydrolase
Kanda_2019_Ann.Surg.Oncol_26_3718 Risk Prediction of Postoperative Pneumonia After Subtotal Esophagectomy Based on Preoperative Serum Cholinesterase Concentrations
Karnaouri_2019_Bioresour.Technol_279_362 Thermophilic enzyme systems for efficient conversion of lignocellulose to valuable products: Structural insights and future perspectives for esterases and oxidative catalysts
Karthivashan_2019_Food.Chem.Toxicol_129_444 Cognitive-enhancing and ameliorative effects of acanthoside B in a scopolamine-induced amnesic mouse model through regulation of oxidative\/inflammatory\/cholinergic systems and activation of the TrkB\/CREB\/BDNF pathway
Khalaf_2019_Naunyn.Schmiedebergs.Arch.Pharmacol_392_685 Combined vildagliptin and memantine treatment downregulates expression of amyloid precursor protein, and total and phosphorylated tau in a rat model of combined Alzheimer's disease and type 2 diabetes
Khazaie_2019_J.Anim.Physiol.Anim.Nutr.(Berl)_103_1619 Modulatory effects of vitamin C on biochemical and oxidative changes induced by acute exposure to diazinon in rat various tissues: Prophylactic and therapeutic roles
Kim_2019_Food.Funct_10_3650 Safflower (Carthamus tinctorius L.) seed attenuates memory impairment induced by scopolamine in mice via regulation of cholinergic dysfunction and oxidative stress
Kimura_2019_Exp.Anim_68_267 Species differences in lipoprotein lipase and hepatic lipase activities: comparative studies of animal models of lifestyle-related diseases
Klaassens_2019_Neuroimage_199_143 Cholinergic and serotonergic modulation of resting state functional brain connectivity in Alzheimer's disease
Ko_2019_Arch.Pharm.Res_42_722 Isoorientin improves scopolamine-induced cognitive impairments by restoring the cholinergic system, antioxidant defense, and p-CREB\/BDNF signaling in the hippocampus and frontal cortex
Kobrlova_2019_Toxicology_423_75 Current approaches to enhancing oxime reactivator delivery into the brain
Koloski_2019_Ticks.Tick.Borne.Dis_10_515 Molecular evidence for the inhibition of cytochrome p450s and cholinesterases in ticks by the repellent DEET
Kong_2019_ACS.Appl.Mater.Interfaces_11_11857 Protein-Inorganic Hybrid Nanoflower-Rooted Agarose Hydrogel Platform for Point-of-Care Detection of Acetylcholine
Koshy_2019_Psychopharmacology.(Berl)_236_1701 Co-treatment with rivastigmine and idalopirdine reduces the propensity for falls in a rat model of falls in Parkinson's disease
Krishna_2019_ACS.Chem.Neurosci_10_4124 Design and Biological Evaluation of Lipoprotein-Based Donepezil Nanocarrier for Enhanced Brain Uptake through Oral Delivery
Kumar_2019_Biochim.Biophys.Acta.Proteins.Proteom_1867_140261 Engineering lipases for temperature adaptation: Structure function correlation
Kuppan_2019_Exp.Eye.Res_186_107668 Elevated serum OxLDL is associated with progression of type 2 Diabetes Mellitus to diabetic retinopathy
Kwon_2019_Biochem.Biophys.Res.Commun_515_565 A caffeic acid-ferulic acid hybrid compound attenuates lipopolysaccharide-mediated inflammation in BV2 and RAW264.7 cells
Lahari_2019_New.Phytol_224_454 Strigolactones enhance root-knot nematode (Meloidogyne graminicola) infection in rice by antagonizing the jasmonate pathway
Larrick_2019_Rejuvenation.Res_22_342 Roads to the Fountain of Youth? Rejuvenating Intestinal Stem Cells
Larsen_2019_J.Vet.Pharmacol.Ther_42_548 In vitro and in vivo effects of chlorpyrifos and cypermethrin on blood cholinesterases in sheep
Lataro_2019_Am.J.Hypertens_32_579 Chronic Treatment With Acetylcholinesterase Inhibitors Attenuates Vascular Dysfunction in Spontaneously Hypertensive Rats
Lee_2019_Mol.Med.Rep_20_3448 Ameliorating effect of Citrus aurantium extracts and nobiletin on betaamyloid (142)induced memory impairment in mice
Leitemperger_2019_Mol.Biol.Rep_46_3399 Behavioural and biochemical parameters in guppy (Poecilia vivipara) following exposure to waterborne zinc in salt or hard water
Leuzy_2019_Eur.J.Nucl.Med.Mol.Imaging_46_1276 Clinical impact of [(18)F]flutemetamol PET among memory clinic patients with an unclear diagnosis
Levinn_2019_ACS.Chem.Biol_14_170 Esterase-Triggered Self-Immolative Thiocarbamates Provide Insights into COS Cytotoxicity
Li_2019_ACS.Appl.Mater.Interfaces_11_15718 Artificial Nanometalloenzymes for Cooperative Tandem Catalysis
Li_2019_Eur.J.Neurol_26_1296 Clinical analysis of Chinese anti-low-density-lipoprotein-receptor-associated protein 4 antibodies in patients with myasthenia gravis
Li_2019_Toxicol.In.Vitro_56_93 Use of high-throughput enzyme-based assay with xenobiotic metabolic capability to evaluate the inhibition of acetylcholinesterase activity by organophosphorous pesticides
Li_2019_Trends.Plant.Sci_24_669 Do Cytokinins and Strigolactones Crosstalk during Drought Adaptation?
Li_2019_Drug.Metab.Dispos_47_843 Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
Li_2019_Analyst_144_2034 Metal coordination polymer induced perylene probe excimer fluorescence and its application in acetylcholinesterase sensing and alpha-fetoprotein immunoassay
Liao_2019_J.Med.Food_22_685 Aster glehni Extract Ameliorates Scopolamine-Induced Cognitive Impairment in Mice
Lind_2019_Int.J.Geriatr.Psychiatry_34_1029 Antidementia medication use by aged care facility residents with dementia
Liu_2019_Food.Funct_10_799 The in silico and in vivo evaluation of puerarin against Alzheimer's disease
Liu_2019_Chem.Commun.(Camb)_55_9797 Molecular recognition of organophosphorus compounds in water and inhibition of their toxicity to acetylcholinesterase
Liu_2019_Environ.Sci.Pollut.Res.Int_26_24695 Single and joint oxidative stress-related toxicity of sediment-associated cadmium and lead on Bellamya aeruginosa
Liu_2019_Vascul.Pharmacol_120_106544 Nox4 and soluble epoxide hydrolase synergistically mediate homocysteine-induced inflammation in vascular smooth muscle cells
Liu_2019_Food.Funct_10_432 Pharmacodynamic and urinary metabolomics studies on the mechanism of Schisandra polysaccharide in the treatment of Alzheimer's disease
Lleo_2019_Mol.Cell.Proteomics_18_546 Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid
Lores-Arnaiz_2019_Exp.Gerontol_118_88 Changes in motor function and brain cortex mitochondrial active oxygen species production in aged mice
Luc_2019_Life.Sci_231_116483 Tackling Alzheimer's disease: Hypothetical synergism between anti-inflammatory and anti-diabetic agents
Lule-Chavez_2019_Neotrop.Entomol_48_706 Detrimental Effects of Induced Antibodies on Aedes aegypti Reproduction
Luo_2019_Neuromuscul.Disord_29_549 Novel compound heterozygous GFPT1 mutations in a family with limb-girdle myasthenia with tubular aggregates
Luo_2019_Langmuir_35_9050 Surfactant Charge Modulates Structure and Stability of Lipase-Embedded Monolayers at Marine-Relevant Aerosol Surfaces
Luo_2019_Chem.Biol.Interact_13ChEPon_308_164 Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on acetylcholinesterase during myogenic differentiation of contractile rat primary skeletal muscle cells
Ma_2019_Int.J.Biol.Macromol_133_1090 Polysaccharide from Spirulina platensis ameliorates diphenoxylate-induced constipation symptoms in mice
Maayah_2019_J.Cardiovasc.Pharmacol_74_235 Role of Cytochrome p450 and Soluble Epoxide Hydrolase Enzymes and Their Associated Metabolites in the Pathogenesis of Diabetic Cardiomyopathy
Mahdavi_2019_Chem.Biodivers_16_e1800488 Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti-Alzheimer's Agents
Mahmoud_2019_Environ.Sci.Pollut.Res.Int_26_20731 Potential role of N-acetylcysteine on chlorpyrifos-induced neurotoxicity in rats
Makhaeva_2019_Chem.Biol.Interact_13ChEPon_308_224 Overview of novel multifunctional agents based on conjugates of gamma-carbolines, carbazoles, tetrahydrocarbazoles, phenothiazines, and aminoadamantanes for treatment of Alzheimer's disease
Manca_2019_J.Alzheimers.Dis_68_1061 Assessment of 18F-Florbetaben Amyloid PET Imaging in Patients with Suspected Alzheimer's Disease and Isolated Increase in Cerebrospinal Fluid Tau Proteins
Marashdeh_2019_Dent.Mater_35_1065 Esterases affect the physical properties of materials used to seal the endodontic space
Marinho_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_222_11 Characterization and kinetic study of the brain and muscle acetylcholinesterase from Danio rerio
Marins_2019_Environ.Sci.Pollut.Res.Int_26_23555 Iron and manganese present in underground water promote biochemical, genotoxic, and behavioral alterations in zebrafish (Danio rerio)
Marquart_2019_Toxicol.In.Vitro_57_76 Human small bowel as model for poisoning with organophosphorus compounds
Marques_2019_Biochim.Biophys.Acta.Mol.Basis.Dis_1865_165529 Cross-talk between guanidinoacetate neurotoxicity, memory and possible neuroprotective role of creatine
Marro_2019_Neuron_103_617 Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons
Masuoka_2019_Neurosci_404_39 Augmentation of Endogenous Acetylcholine Uptake and Cholinergic Facilitation of Hippocampal Long-Term Potentiation by Acetylcholinesterase Inhibition
Matsumoto_2019_Biochem.Biophys.Res.Commun_515_248 N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase
Matsuo_2019_Geriatr.Gerontol.Int_19_780 Reference range of clinical blood tests in physically independent patients of advanced age with groin hernia in a Japanese hospital
McMacken_2019_Hum.Mol.Genet_28_2339 Salbutamol modifies the neuromuscular junction in a mouse model of ColQ myasthenic syndrome
Medhat_2019_Mol.Biol.Rep_46_4517 Evaluation of urinary 8-hydroxy-2-deoxyguanosine level in experimental Alzheimer's disease: Impact of carvacrol nanoparticles
Mesulam_2019_Neurology_92_e1580 Cortical cholinergic denervation in primary progressive aphasia with Alzheimer pathology
Mirto-Aguilar_2019_Neurourol.Urodyn_38_893 Urethral regions with differential tissular composition may underlie urinary continence and voiding function in female rats
Mishra_2019_Bioorg.Med.Chem_27_895 Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018)
Miyauchi-Wakuda_2019_J.Med.Food_22_789 Effect of Royal Jelly on Mouse Isolated Ileum and Gastrointestinal Motility
Mizokami_2019_Intern.Med_58_2669 Congenital Primary Hypothyroidism with the Homozygous Nonsense Mutation P.K1374* in the Thyroglobulin Gene and a Normal-sized Thyroid Gland on Levothyroxine Replacement
Mokrani_2019_Mol.Inform_38_e1800118 Identification of New Potent Acetylcholinesterase Inhibitors Using Virtual Screening and in vitro Approaches
Mondal_2019_ACS.Chem.Neurosci_10_2609 Potential Neuroprotective Peptide Emerged from Dual Neurotherapeutic Targets: A Fusion Approach for the Development of Anti-Alzheimer's Lead
Morozzi_2019_J.Med.Chem_62_8178 Targeting GNE Myopathy: A Dual Prodrug Approach for the Delivery of N-Acetylmannosamine 6-Phosphate
Mortazavi_2019_J.Cell.Biochem_120_14847 Organochlorine and organophosphorus pesticides and bladder cancer: A case-control study
Mukherjee_2019_Environ.Sci.Pollut.Res.Int_26_23442 Physiological response of fish under variable acidic conditions: a molecular approach through the assessment of an eco-physiological marker in the brain
Muley_2019_Ultrason.Sonochem_55_174 Stabilization of cutinase by covalent attachment on magnetic nanoparticles and improvement of its catalytic activity by ultrasonication
Munir_2019_J.Mol.Neurosci_67_445 Biochemical Analysis and Association of Butyrylcholinesterase SNPs rs3495 and rs1803274 with Substance Abuse Disorder
Myers_2019_Chem.Biol.Interact_13ChEPon_308_170 Human plasma-derived butyrylcholinesterase is behaviorally safe and effective in cynomolgus macaques (Macaca fascicularis) challenged with soman
Nagumo_2019_Bioorg.Med.Chem.Lett_29_2475 Comparative analysis of stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors with neuroprotective and anti-inflammatory activities
Naidoo_2019_Phytochemistry_163_187 Synthesis of potent neuroprotective butenolides based on plant smoke derived 3,4,5-Trimethylfuran-2(5H)-one and 3-methyl-2H-furo[2,3-c]pyrone-2-one
Nam_2019_ACS.Chem.Neurosci_10_3386 Orobol: An Isoflavone Exhibiting Regulatory Multifunctionality against Four Pathological Features of Alzheimer's Disease
Narayan_2019_Br.J.Clin.Pharmacol_85_1957 Anticholinergic medicines use among older adults before and after initiating dementia medicines
Nascimento_2019_Bioprocess.Biosyst.Eng_42_1235 Insights into the effect of imidazolium-based ionic liquids on chemical structure and hydrolytic activity of microbial lipase
Nasr_2019_Life.Sci_226_117 Neuroprotective effects of novel nanosystems simultaneously loaded with vinpocetine and piracetam after intranasal administration
Nepovimova_2019_Curr.Alzheimer.Res_16_333 N-alkylated Tacrine Derivatives as Potential Agents in Alzheimer's Disease Therapy
Nervo_2019_Toxicology_424_152232 Respiratory failure triggered by cholinesterase inhibitors may involve activation of a reflex sensory pathway by acetylcholine spillover
Nigam_2019_Fish.Physiol.Biochem_45_1355 Characterisation of cholinesterases in mucous secretions and their localisation in epidermis of Labeo rohita and Cirrhinus mrigala
Nikolic_2019_Environ.Sci.Pollut.Res.Int_26_6890 Laboratory bioassays on the response of honey bee (Apis mellifera L.) glutathione S-transferase and acetylcholinesterase to the oral exposure to copper, cadmium, and lead
Ning_2019_Fish.Shellfish.Immunol_87_534 Proteomic and metabolomic responses in hepatopancreas of whiteleg shrimp Litopenaeus vannamei infected by microsporidian Enterocytozoon hepatopenaei
Nishihira_2019_Acta.Neuropathol_138_167 Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes
Niznik_2019_J.Am.Geriatr.Soc_67_1871 Factors Associated With Deprescribing Acetylcholinesterase Inhibitors in Older Nursing Home Residents With Severe Dementia
Nkoom_2019_Environ.Sci.Pollut.Res.Int_26_5704 Bioconcentration, behavioral, and biochemical effects of the non-steroidal anti-inflammatory drug diclofenac in Daphnia magna
Nobsathian_2019_J.Econ.Entomol_112_1683 Insecticidal Effects of Triterpene Glycosides Extracted From Holothuria atra (Echinodermata: Holothuroidea) Against Spodoptera litura (Lepidoptera: Noctuidae)
Noufi_2019_Drugs.Aging_36_719 Use of Cholinesterase Inhibitors in Non-Alzheimer's Dementias
Novichkova_2019_Chem.Biol.Interact_13ChEPon_309_108699 The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability
Nunes_2019_Environ.Sci.Pollut.Res.Int_26_7873 Acute ecotoxicological effects of salicylic acid on the Polychaeta species Hediste diversicolor: evidences of low to moderate pro-oxidative effects
Nunes_2019_Environ.Sci.Pollut.Res.Int_26_13551 Study of the effects of zinc pyrithione in biochemical parameters of the Polychaeta Hediste diversicolor: evidences of neurotoxicity at ecologically relevant concentrations
Ochoa_2019_Mol.Inform_38_e1800126 Prediction of Ligands Binding Acetylcholinesterase with Potential Antidotal Activity: A Virtual Screening Approach
Okesola_2019_J.Integr.Med_17_125 Neuromodulatory effects of ethyl acetate fraction of Zingiber officinale Roscoe extract in rats with lead-induced oxidative stress
Oliver_2019_Mol.Cell.Neurosci_96_47 Small molecules as therapeutic drugs for Alzheimer's disease
Orhan_2019_Chem.Biodivers_16_e1900017 Profiling Auspicious Butyrylcholinesterase Inhibitory Activity of Two Herbal Molecules: Hyperforin and Hyuganin C
Ouardi_2019_J.Mol.Neurosci_69_17 Gestational and Lactational Exposure to Malathion Affects Antioxidant Status and Neurobehavior in Mice Pups and Offspring
Owagboriaye_2019_Environ.Sci.Pollut.Res.Int_26_14502 Comparative studies on endogenic stress hormones, antioxidant, biochemical and hematological status of metabolic disturbance in albino rat exposed to roundup herbicide and its active ingredient glyphosate
Ozawa_2019_Neurosci.Lett_698_146 Acetylcholine suppresses the increase of glia fibrillary acidic protein expression via acetylcholine receptors in cAMP-induced astrocytic differentiation of rat C6 glioma cells
Ozek_2019_Chem.Biodivers_16_e1800672 Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes
Palanivelu_2019_J.Cell.Biochem_120_10777 Acetylcholinesterase with mesoporous silica: Covalent immobilization, physiochemical characterization, and its application in food for pesticide detection
Pan_2019_Life.Sci_222_112 Linarin improves the dyskinesia recovery in Alzheimer's disease zebrafish by inhibiting the acetylcholinesterase activity
Pan_2019_Bioorg.Med.Chem.Lett_29_2150 Dual functional cholinesterase and PDE4D inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of tacrine-pyrazolo[3,4-b]pyridine hybrids
Patel_2019_ACS.Chem.Neurosci_10_3635 Novel Multitarget Directed Triazinoindole Derivatives as Anti-Alzheimer Agents
Patrick_2019_Drug.Metab.Dispos_47_764 Potential for Underestimation of d-Methylphenidate Bioavailability Using Chiral Derivatization\/Gas Chromatography
Perin_2019_Microb.Pathog_132_137 Cholinesterase's activities of infected mice by Brucella ovis
Petrov_2019_Parasitol.Res_118_1193 Architecture of the nervous system in metacercariae of Diplostomum pseudospathaceum Niewiadomska, 1984 (Digenea)
Philpot_2019_Cancer.Chemother.Pharmacol_84_579 Spatial memory deficits in mice induced by chemotherapeutic agents are prevented by acetylcholinesterase inhibitors
Pinheiro_2019_Curr.Alzheimer.Res_16_418 Therapeutic Strategies Targeting Amyloid-beta in Alzheimer's Disease
Poetsch_2019_Strahlenther.Onkol_195_430 The value of pretreatment serum butyrylcholinesterase level as a novel prognostic biomarker in patients with cervical cancer treated with primary (chemo-)radiation therapy
Porro_2019_Biochem.Pharmacol_163_119 Characterization of aspirin esterase activity in health and disease: In vitro and ex vivo studies
Portela_2019_Neurochem.Res_44_2202 Ilex paraguariensis Attenuates Changes in Mortality, Behavioral and Biochemical Parameters Associated to Methyl Malonate or Malonate Exposure in Drosophila melanogaster
Puelles_2019_Kidney.Int_96_505 Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis
Qi_2019_J.Nat.Med_73_769 Pyrrole 2-carbaldehyde derived alkaloids from the roots of Angelica dahurica
Qi_2019_Anal.Bioanal.Chem_411_2577 Acetylcholinesterase-functionalized two-dimensional photonic crystal for the sensing of G-series nerve agents
Qin_2019_Angew.Chem.Int.Ed.Engl_58_4291 Isolation and Synthesis of Novel Meroterpenoids from Rhodomyrtus tomentosa: Investigation of a Reactive Enetrione Intermediate
Quero_2019_Environ.Toxicol.Chem_38_1692 Plasma Cholinesterase Activity in Wild Birds from Undisturbed Woodlands in the Central Monte Desert
Raheja_2019_Life.Sci_221_196 Aegle marmelos leaf extract ameliorates the cognitive impairment and oxidative stress induced by intracerebroventricular streptozotocin in male rats
Rameshrad_2019_Daru_27_341 Pharmacology of dipeptidyl peptidase-4 inhibitors and its use in the management of metabolic syndrome: a comprehensive review on drug repositioning
Reeve_2019_Med.J.Aust_210_174 Deprescribing cholinesterase inhibitors and memantine in dementia: guideline summary
Richter_2019_EBioMedicine_41_649 Optogenetic augmentation of the hypercholinergic endophenotype in DYT1 knock-in mice induced erratic hyperactive movements but not dystonia
Richter_2019_ChemMedChem_14_469 Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1-Activated Prodrugs as Antiviral Agents
Rohlman_2019_Neurotoxicol_74_1 Occupational pesticide exposure and symptoms of attention deficit hyperactivity disorder in adolescent pesticide applicators in Egypt
Rojas_2019_Neurobiol.Dis__104399 A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition
Rosado-Solano_2019_J.Agric.Food.Chem_67_9210 Synthesis, Biological Evaluation and In Silico Computational Studies of 7-Chloro-4-(1H-1,2,3-triazol-1-yl)quinoline Derivatives: Search for New Controlling Agents against Spodoptera frugiperda (Lepidoptera: Noctuidae) Larvae
Rosenberg_2019_Chem.Biol.Interact_309_108712 Aerosolized recombinant human butyrylcholinesterase delivered by a nebulizer provides long term protection against inhaled paraoxon in macaques
Roumiani_2019_Ultrason.Sonochem_55_207 Sonochemical synthesis of a nanodandelion tin(IV) complex with carbacylamidophosphate ligand as anti-Alzheimer agent: Molecular docking study
Saad_2019_Environ.Sci.Pollut.Res.Int_26_6801 Insecticidal potential and repellent and biochemical effects of phenylpropenes and monoterpenes on the red flour beetle, Tribolium castaneum Herbst
Saleem_2019_Food.Chem.Toxicol_131_110535 Pharmacological, phytochemical and in-vivo toxicological perspectives of a xero-halophyte medicinal plant: Zaleya pentandra (L.) Jeffrey
Samad_2019_Metab.Brain.Dis_34_1091 Protective effect of gallic acid against arsenic-induced anxiety-\/depression- like behaviors and memory impairment in male rats
Samal_2019_Environ.Sci.Pollut.Res.Int_26_8039 Setal-epidermal, muscular and enzymatic anomalies induced by certain agrochemicals in the earthworm Eudrilus eugeniae (Kinberg)
Sanahuja_2019_Fish.Shellfish.Immunol_89_428 Comparison of several non-specific skin mucus immune defences in three piscine species of aquaculture interest
Saxena_2019_Curr.Top.Med.Chem_19_264 Target Enzyme in Alzheimer's Disease: Acetylcholinesterase Inhibitors
Schopfer_2019_Chem.Res.Toxicol_32_762 Mass Spectrometry Identifies Isopeptide Cross-Links Promoted by Diethylphosphorylated Lysine in Proteins Treated with Chlorpyrifos Oxon
Schweitzer_2019_Liver.Int_39_914 Second-line chemotherapy in biliary tract cancer: Outcome and prognostic factors
Seo_2019_Am.J.Clin.Nutr_110_330 Prognostic significance of serum cholinesterase in patients with acute decompensated heart failure: a prospective comparative study with other nutritional indices
Sergeant_2019_Neurobiol.Dis_129_217 New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease
Sezer_2019_Bull.Environ.Contam.Toxicol_102_341 Effects of Copper Oxide Nanoparticles on Tissue Accumulation and Antioxidant Enzymes of Galleria mellonella L
Sha_2019_J.Agric.Food.Chem_67_10342 Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2\/HO-1-Mediated Oxidative Stress in Mice
Sha_2019_Chem.Biol.Interact_13ChEPon_309_108686 Effects of astrocyte conditioned medium on neuronal AChE expression upon 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure
Shanmuganathan_2019_Nitric.Oxide_91_52 Amyloid-beta induced neuropathological actions are suppressed by Padina gymnospora (Phaeophyceae) and its active constituent alpha-bisabolol in Neuro2a cells and transgenic Caenorhabditis elegans Alzheimer's model
Sharma_2019_Mol.Med.Rep_20_1479 Cholinesterase inhibitors as Alzheimer's therapeutics (Review)
Sharma_2019_Expert.Rev.Neurother_19_359 Traditional Ayurvedic and herbal remedies for Alzheimer's disease: from bench to bedside
Shen_2019_Brain.Behav.Immun_81_535 Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epilepsy-associated depression in the LiCl-pilocarpine post-status epilepticus rat model
Shi_2019_Int.J.Biol.Macromol_136_512 Naja atra cardiotoxins enhance the protease activity of chymotrypsin
Shin_2019_Cell.Chem.Biol_26_1036 Diacylglycerol Lipase-beta Is Required for TNF-alpha Response but Not CD8(+) T Cell Priming Capacity of Dendritic Cells
Sicak_2019_Chirality_31_603 Novel fluorine-containing chiral hydrazide-hydrazones: Design, synthesis, structural elucidation, antioxidant and anticholinesterase activity, and in silico studies
Singh_2019_Inorg.Chem_58_9773 Metal-Organocatalyst for Detoxification of Phosphorothioate Pesticides: Demonstration of Acetylcholine Esterase Activity
Singh_2019_Steroids_148_114 16,17-N'-(alky\/arylsulfonyl)pyrazoline substituted neuroprotective heterosteroids: Synthesis, molecular docking and preclinical efficacy\/toxicity studies in rodents
Sin-Yee_2019_ACS.Appl.Mater.Interfaces_11_4799 A Luminescence Turn-On Assay for Acetylcholinesterase Activity and Inhibitor Screening Based on Supramolecular Self-Assembly of Alkynylplatinum(II) Complexes on Coordination Polymer
Song_2019_Int.J.Biol.Macromol_137_261 Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening
Spang_2019_Nat.Microbiol_4_1138 Proposal of the reverse flow model for the origin of the eukaryotic cell based on comparative analyses of Asgard archaeal metabolism
Adeyinka_2019_Sci.Rep_9_13629 Identification and validation of potential reference gene for effective dsRNA knockdown analysis in Chilo partellus
Atmaca_2019_Arch.Pharm.(Weinheim)__e1900200 Synthesis of beta-amino acid derivatives and their inhibitory profiles against some metabolic enzymes
Badawy_2019_Toxicol.Mech.Methods__1 Validation and kinetic of enzymatic method for the detection of organophosphate insecticides based on cholinesterase inhibition
Bendjedou_2019_Nat.Prod.Res__1 Alkaloids and sesquiterpenes from roots and leaves of Lycium europaeum L. (Solanaceae) with antioxidant and anti-acetylcholinesterase activities
Deveci_2019_Iran.J.Pharm.Res_18_903 Chemical Composition, Antioxidant, Anticholinesterase and Anti-Tyrosinase Activities of Essential Oils of Two Sideritis Species from Turkey
Elufioye_2019_Antioxidants.(Basel)_8_ Antioxidant and Anticholinesterase Activities of Macrosphyra Longistyla (DC) Hiern Relevant in the Management of Alzheimer's Disease
Falfushynska_2019_Environ.Pollut_255_113213 Difference in biochemical markers in the gibel carp (Carassius auratus gibelio) upstream and downstream of the hydropower plant
Fleet_2019_CMAJ_191_E1018 Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study
Gamez-Valero_2019_Sci.Rep_9_13282 Comprehensive proteomic profiling of plasma-derived Extracellular Vesicles from dementia with Lewy Bodies patients
Ghafouri-Khosrowshahi_2019_J.Educ.Health.Promot_8_149 Chronic exposure to organophosphate pesticides as an important challenge in promoting reproductive health: A comparative study
Greiman_2019_Ment.Health.Clin_9_309 Adverse outcomes of abrupt switch and discontinuation of acetylcholinesterase inhibitors in dementia with Lewy bodies: Case report and literature review
Helman_2019_Regul.Toxicol.Pharmacol__104480 Quantitative prediction of repeat dose toxicity values using GenRA
Herman_2019_Int.J.Mol.Sci_20_ Effect of Central Injection of Neostigmine on the Bacterial Endotoxin Induced Suppression of GnRH\/LH Secretion in Ewes during the Follicular Phase of the Estrous Cycle
Huang_2019_Oncotarget_10_5419 SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells
Nabavi_2019_Food.Chem.Toxicol_134_110822 Phosphodiesterase inhibitors say NO to Alzheimer's disease
Saito_2019_Free.Radic.Biol.Med_145_20 Early administration of galantamine from preplaque phase suppresses oxidative stress and improves cognitive behavior in APPswe\/PS1dE9 mouse model of Alzheimer's disease
Schilter_2019_Food.Addit.Contam.Part.A.Chem.Anal.Control.Expo.Risk.Assess__1 Value and limitation of in vitro bioassays to support the application of the threshold of toxicological concern to prioritise unidentified chemicals in food contact materials
Suchaichit_2019_Nat.Prod.Res__1 A new antibacterial tirucallane from Walsura trichostemon roots
Tlili_2019_PLoS.One_14_e0213049 Biochemical profile and in vitro biological activities of extracts from seven folk medicinal plants growing wild in southern Tunisia
Voss_2019_J.Struct.Biol_208_107390 Arabidopsis immunity regulator EDS1 in a PAD4\/SAG101-unbound form is a monomer with an inherently inactive conformation
Wang_2019_Environ.Pollut_255_113218 Clethodim exposure induced development toxicity and behaviour alteration in early stages of zebrafish life
Yuan_2019_J.Chromatogr.A__460506 Online acetylcholinesterase inhibition evaluation by high-performance liquid chromatography-mass spectrometry hyphenated with an immobilized enzyme reactor
Zivkovic_2019_Mediators.Inflamm_2019_9258509 Response to: Comment on A Sustained Reduction in Serum Cholinesterase Enzyme Activity Predicts Patient Outcome following Sepsis
Srivastava_2019_Bioorg.Med.Chem_27_3650 Design, synthesis, and evaluation of novel N-(4-phenoxybenzyl)aniline derivatives targeting acetylcholinesterase, beta-amyloid aggregation and oxidative stress to treat Alzheimer's disease
Stein_2019_Brain.Res.Bull_152_134 Impaired hippocampal and thalamic acetylcholine release in P301L tau-transgenic mice
Stojiljkovic_2019_Toxicology_416_62 Prophylactic potential of memantine against soman poisoning in rats
Suarez-Lopez_2019_Int.J.Hyg.Environ.Health_222_981 Associations of acetylcholinesterase activity with depression and anxiety symptoms among adolescents growing up near pesticide spray sites
Sugahara_2019_J.Am.Soc.Nephrol_30_962 Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes
Sugarman_2019_Pharmacol.Biochem.Behav_181_86 Feasibility and effects of galantamine on cognition in humans with cannabis use disorder
Swale_2019_Pest.Manag.Sci_75_2068 Is DEET a dangerous neurotoxicant?
Swarbreck_2019_Plant.J_98_607 Impairment in karrikin but not strigolactone sensing enhances root skewing in Arabidopsis thaliana
Szeremeta_2019_Prostaglandins.Other.Lipid.Mediat_142_59 Low mRNA expression and activity of monoacylglycerol lipase in human SH-SY5Y neuroblastoma cells
Tabrez_2019_Curr.Pharm.Des_25_2108 Computational and Kinetic Studies of Acetylcholine Esterase Inhibition by Phenserine
Tang_2019_Int.J.Biol.Macromol_135_303 Effect of Salvia miltiorrhiza on acetylcholinesterase: Enzyme kinetics and interaction mechanism merging with molecular docking analysis
Tao_2019_Mol.Oncol_13_1018 CA10 and CA11 negatively regulate neuronal activity-dependent growth of gliomas
Taskin_2019_Semin.Diagn.Pathol_36_240 Lipase hypersecretion syndrome: A distinct form of paraneoplastic syndrome specific to pancreatic acinar carcinomas
Taylor_2019_Environ.Toxicol.Chem_38_1294 Effects of Sublethal Chlorpyrifos Exposure on Postlarval American Lobster (Homarus americanus)
Tehrani_2019_Chem.Biodivers_16_e1900144 Design, Synthesis, and Cholinesterase Inhibition Assay of Coumarin-3-carboxamide-N-morpholine Hybrids as New Anti-Alzheimer Agents
Telles-Longui_2019_Br.J.Pharmacol_176_3193 alpha7 nicotinic ACh receptors are necessary for memory recovery and neuroprotection promoted by attention training in amyloid-beta-infused mice
Thancharoen_2019_Drugs.Aging_36_435 Ginkgo biloba Extract (EGb761), Cholinesterase Inhibitors, and Memantine for the Treatment of Mild-to-Moderate Alzheimer's Disease: A Network Meta-Analysis
Thomas_2019_Neurotox.Res_36_323 In Vivo Evaluation of A1 Adenosine Agonists as Novel Anticonvulsant Medical Countermeasures to Nerve Agent Intoxication in a Rat Soman Seizure Model
Timoumi_2019_Toxicol.Lett_312_173 Metabolism of triflumuron in the human liver: Contribution of cytochrome P450 isoforms and esterases
Torres_2019_Pharmacol.Ther_198_34 Modulating Wnt signaling at the root: Porcupine and Wnt acylation
Trabelsi_2019_Environ.Sci.Pollut.Res.Int_26_22197 Redox status and fatty acid composition of Mactra corallina digestive gland following exposure to acrylamide
Tripathi_2019_Bioorg.Med.Chem_27_1327 Design and development of novel N-(pyrimidin-2-yl)-1,3,4-oxadiazole hybrids to treat cognitive dysfunctions
Trotter_2019_J.Cell.Biol_218_2677 Synaptic neurexin-1 assembles into dynamically regulated active zone nanoclusters
Troyano-Rodriguez_2019_Biol.Psychiatry_85_1046 Neuroligin-2 Determines Inhibitory Synaptic Transmission in the Lateral Septum to Optimize Stress-Induced Neuronal Activation and Avoidance Behavior
Tu_2019_Bioorg.Med.Chem.Lett_29_1194 Bioactivity-guided identification of flavonoids with cholinesterase and beta-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa
Tyagi_2019_Int.J.Biol.Macromol_140_415 Voltammetric measurements of neurotransmitter-acetylcholine through metallic nanoparticles embedded 2-D material
Umar_2019_Bioorg.Med.Chem_27_3156 Naphthalene-triazolopyrimidine hybrid compounds as potential multifunctional anti-Alzheimer's agents
Valladales-Restrepo_2019_Geriatr.Gerontol.Int_19_913 Potentially inappropriate prescriptions of anticholinergics drugs in Alzheimer's disease patients
Van Meter_2019_Environ.Toxicol.Chem_38_1052 Agrochemical Mixtures and Amphibians: The Combined Effects of Pesticides and Fertilizer on Stress, Acetylcholinesterase Activity, and Bioaccumulation in a Terrestrial Environment
Vasantha-Srinivasan_2019_Microb.Pathog_128_281 Aspergillus flavus (Link) toxins reduces the fitness of dengue vector Aedes aegypti (Linn.) and their non-target toxicity against aquatic predator
Venkatesh_2019_J.Pharm.Pharmacol_71_996 Molecular mechanism of tuberoinfundibular peptide of 39 on glucocorticoid receptor mediated glutamate\/GABA imbalance and cerebral abnormalities against cognitive deficit model
Vilhena_2019_Vet.Comp.Oncol_17_394 Acute phase proteins and biomarkers of oxidative status in feline spontaneous malignant mammary tumours
Vinje_2019_Hum.Mol.Genet_28_3043 Characterization of the mechanisms by which missense mutations in the lysosomal acid lipase gene disrupt enzymatic activity
Vishnu_2019_ChemMedChem_14_1359 Experimental and Computational Evaluation of Piperonylic Acid Derived Hydrazones Bearing Isatin Moieties as Dual Inhibitors of Cholinesterases and Monoamine Oxidases
Volobuff_2019_Curr.Pharm.Biotechnol_20_302 Antitumoral and Anticholinesterasic Activities of the Seven Species from Rubiaceae
von Arnim_2019_Z.Gerontol.Geriatr_52_309 Diagnosis and treatment of cognitive impairment
Wajid_2019_Bioorg.Med.Chem_27_4030 Microwave-Assisted Organic Synthesis, structure-activity relationship, kinetics and molecular docking studies of non-cytotoxic benzamide derivatives as selective butyrylcholinesterase inhibitors
Wancura_2019_Appl.Microbiol.Biotechnol_103_7805 Improving the soluble lipase-catalyzed biodiesel production through a two-step hydroesterification reaction system
Wang_2019_Virol.Sin_34_59 Exosomes Released from Rabies Virus-Infected Cells May be Involved in the Infection Process
Wang_2019_Anal.Chem_91_7280 Multifunctional Cellular Beacons with in Situ Synthesized Quantum Dots Make Pathogen Detectable with the Naked Eye
Wang_2019_J.Agric.Food.Chem_67_4071 Fabricating an Acetylcholinesterase Modulated UCNPs-Cu(2+) Fluorescence Biosensor for Ultrasensitive Detection of Organophosphorus Pesticides-Diazinon in Food
Wang_2019_J.Am.Chem.Soc_141_2061 Observation of Acetylcholinesterase in Stress-Induced Depression Phenotypes by Two-Photon Fluorescence Imaging in the Mouse Brain
Wen_2019_Toxicology_416_15 Hepatic carboxylesterases are differentially regulated in PPARalpha-null mice treated with perfluorooctanoic acid
Willemse_2019_Clin.Chim.Acta_497_204 Pre-analytical stability of novel cerebrospinal fluid biomarkers
Wu_2019_Mar.Biotechnol.(NY)_21_707 First Genome-wide Association Analysis for Growth Traits in the Largest Coral Reef-Dwelling Bony Fishes, the Giant Grouper (Epinephelus lanceolatus)
Wu_2019_Curr.Top.Med.Chem_19_187 Small Molecule Natural Products and Alzheimer's Disease
Wu_2019_Neuron_102_621 Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways
Xia_2019_Neurosci.Bull_35_497 Neuroligins Differentially Mediate Subtype-Specific Synapse Formation in Pyramidal Neurons and Interneurons
Xiao_2019_J.Ethnopharmacol_235_100 Impact of the Chinese herbal medicines on dual antiplatelet therapy with clopidogrel and aspirin: Pharmacokinetics and pharmacodynamics outcomes and related mechanisms in rats
Xu_2019_Lab.Invest_99_1078 Central cholinergic neuronal degeneration promotes the development of postoperative cognitive dysfunction
Yadav_2019_Neurochem.Res_44_1665 Molecular Docking and Cognitive Impairment Attenuating Effect of Phenolic Compound Rich Fraction of Trianthema portulacastrum in Scopolamine Induced Alzheimer's Disease Like Condition
Yang_2019_J.Nat.Prod_82_792 Bialternacins A-F, Aromatic Polyketide Dimers from an Endophytic Alternaria sp
Yao_2019_Methods.Appl.Fluoresc_7_035006 A highly sensitive and low-background fluorescence assay for pesticides residues based on hybridization chain reaction amplification assisted by magnetic separation
Yu_2019_Food.Chem.Toxicol_125_376 The effects of pinoresinol on cholinergic dysfunction-induced memory impairments and synaptic plasticity in mice
Yu_2019_J.Atheroscler.Thromb_26_762 Serum Triglyceride Lipase Concentrations are Independent Risk Factors for Coronary Artery Disease and In-Stent Restenosis
Zaarur_2019_Mol.Metab_27_75 ATGL-1 mediates the effect of dietary restriction and the insulin\/IGF-1 signaling pathway on longevity in C. elegans
Zaki_2019_Appl.Microbiol.Biotechnol_103_5867 Production and enhancement of the acetylcholinesterase inhibitor, huperzine A, from an endophytic Alternaria brassicae AGF041
Zambrano_2019_Biochim.Biophys.Acta.Biomembr_1861_1078 The acetylcholinesterase (AChE) inhibitor and anti-Alzheimer drug donepezil interacts with human erythrocytes
Zarowitz_2019_J.Am.Geriatr.Soc_67_1508 Navigating the Minefield of QTc Interval-Prolonging Therapy in Nursing Facility Residents
Zatkova_2019_J.Mol.Neurosci_68_171 Activation of the Oxytocin Receptor Modulates the Expression of Synaptic Adhesion Molecules in a Cell-Specific Manner
Zendehdel_2019_Work_63_355 Neurological risk assessment of co-exposure to heavy metals (chromium and nickel) in chromium-electroplating workers
Zhan_2019_Br.J.Oral.Maxillofac.Surg_57_317 Should we pay attention to the aberrant nerve communication between the lingual and mylohyoid nerves?
Zhang_2019_Biochemistry_58_2978 Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase
Zhang_2019_J.Control.Release_296_14 Reassembly of native components with donepezil to execute dual-missions in Alzheimer's disease therapy
Zhang_2019_Cancer.Lett_465_36 Excipient-free nanodispersion of 7-ethyl-10-hydroxycamptothecin exerts potent therapeutic effects against pancreatic cancer cell lines and patient-derived xenografts
Zhang_2019_Neurotoxicol.Teratol_73_54 Screening for neurotoxic potential of 15 flame retardants using freshwater planarians
Zhang_2019_J.Am.Chem.Soc_141_14643 A Flexible Acetylcholinesterase-Modified Graphene for Chiral Pesticide Sensor
Zhang_2019_J.Econ.Entomol_112_1285 Transcript-Level Analysis of Detoxification Gene Mutation-Mediated Chlorpyrifos Resistance in Laodelphax striatellus (Hemiptera: Delphacidae)
Zhang_2019_Biotechnol.Lett_41_1223 Purification, identification and characterization of an esterase with high enantioselectivity to (S)-ethyl indoline-2-carboxylate
Zhou_2019_Reprod.Toxicol_85_19 Redox regulation of hormone sensitive lipase: Potential role in the mechanism of MEHP-induced stimulation of basal steroid synthesis in MA-10 Leydig cells
Zhu_2019_Bioorg.Med.Chem.Lett_29_1325 Design, synthesis, evaluation and molecular modeling study of 4-N-phenylaminoquinolines for Alzheimer disease treatment
Zhu_2019_Drugs.Aging_36_875 Sex Differences in the Prevalent Use of Oral Formulations of Cholinesterase Inhibitors in Older Adults with Dementia
Zhu_2019_J.Agric.Food.Chem_67_10534 Structural Features and Digestive Behavior of Fucosylated Chondroitin Sulfate from Sea Cucumbers Stichopus japonicus
Ziemba-Davis_2019_J.Arthroplasty_34_S343 Identifiable Risk Factors to Minimize Postoperative Urinary Retention in Modern Outpatient Rapid Recovery Total Joint Arthroplasty
Zou_2019_Anal.Bioanal.Chem_411_2905 Monocrotophos detection with a bienzyme biosensor based on ionic-liquid-modified carbon nanotubes
Agbo_2019_Molecules_24_ Inhibitory Effects of Novel 7-Substituted 6-iodo-3-O-Flavonol Glycosides against Cholinesterases and beta-secretase Activities, and Evaluation for Potential Antioxidant Properties
Cui_2019_Cancer.Genet_239_54 A new prognostic factor of breast cancer: High carboxyl ester lipase expression related to poor survival
Dundar_2019_Bioorg.Chem_92_103304 Novel pyridazinone derivatives as butyrylcholinesterase inhibitors
Feng_2019_Commun.Biol_2_344 Bright split red fluorescent proteins for the visualization of endogenous proteins and synapses
Li_2019_Front.Mol.Neurosci_12_213 A Conserved Tyrosine Residue in Slitrk3 Carboxyl-Terminus Is Critical for GABAergic Synapse Development
Niu_2019_Drug.Des.Devel.Ther_13_3009 Network pharmacology study on the active components of Pterocypsela elata and the mechanism of their effect against cerebral ischemia
Plazas_2019_Phytochemistry_168_112128 Metabolomic profiling of Zanthoxylum species: Identification of anti-cholinesterase alkaloids candidates
Sharma_2019_J.Chem.Neuroanat__101684 Mobile phone induced cognitive and neurochemical consequences
Wang_2019_Cell.Rep_28_3395 Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD
Yang_2019_Bioorg.Chem_92_103294 Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening
Zengin_2019_Food.Res.Int_125_108610 Comprehensive approaches on the chemical constituents and pharmacological properties of flowers and leaves of American basil (Ocimum americanum L)
Zhai_2019_J.Asian.Nat.Prod.Res__1 Two new naphthoate derivatives from Morinda officinalis
Zhao_2019_ACS.Omega_4_15234 Water-like Dual-Functionalized Ionic Liquids for Enzyme Activation
Dutta_2019_Mol.Ther_27_442 A Neutralizing Aptamer to TGFBR2 and miR-145 Antagonism Rescue Cigarette Smoke- and TGF-beta-Mediated CFTR Expression
Garcia-Avila_2019_Temperature.(Austin)_6_132 What is new about mild temperature sensing? A review of recent findings
Kuprys_2019_Alcohol_77_11 Summary of the 2018 Alcohol and Immunology Research Interest Group (AIRIG) meeting
Lallai_2019_eNeuro_6_ Nicotine Acts on Cholinergic Signaling Mechanisms to Directly Modulate Choroid Plexus Function
Lin_2019_Am.J.Respir.Cell.Mol.Biol_61_162 Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia
Lopez-Romero_2019_Channels.(Austin)_13_207 TRP ion channels: Proteins with conformational flexibility
Pushkin_2019_PLoS.One_14_e0211346 Cannabinoid and nicotine exposure during adolescence induces sex-specific effects on anxiety- and reward-related behaviors during adulthood
Saidane_2019_Joint.Bone.Spine_86_411 Dietary fibers in osteoarthritis: What are the evidences?
Teerapuncharoen_2019_Ann.Am.Thorac.Soc_16_150 Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction and Radiographic Bronchiectasis in Current and Former Smokers: A Cross-Sectional Study
Trellu_2019_Arthritis.Res.Ther_21_18 Impairment of glyoxalase-1, an advanced glycation end-product detoxifying enzyme, induced by inflammation in age-related osteoarthritis
Zakrzewicz_2019_Front.Immunol_10_664 SLPI Inhibits ATP-Mediated Maturation of IL-1beta in Human Monocytic Leukocytes: A Novel Function of an Old Player
Bai_2019_Eur.J.Med.Chem_183_111737 Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease
Bicer_2019_J.Biochem.Mol.Toxicol__e22401 Synthesis of novel bis-sulfone derivatives and their inhibition properties on some metabolic enzymes including carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase
Dorababu_2019_Bioorg.Chem_93_103299 Critical evaluation of current Alzheimer's drug discovery (2018-19) & futuristic Alzheimer drug model approach
El-Sayed_2019_Bioorg.Chem_93_103312 Design, synthesis, in vitro and in vivo evaluation of novel pyrrolizine-based compounds with potential activity as cholinesterase inhibitors and anti-Alzheimer's agents
Hamza_2019_PeerJ_7_e7460 Evaluation of the effects of the green nanoparticles zinc oxide on monosodium glutamate-induced toxicity in the brain of rats
Khan_2019_BMJ.Case.Rep_12_ Coexistence of myasthenia gravis with hypokalemic periodic paralysis: a rare presentation
Kisby_2019_J.Alzheimers.Dis.Parkinsonism_9_ Alzheimer's Disease and Its Potential Alternative Therapeutics
Mamedova_2019_Bioorg.Chem_93_103313 Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: Synthesis, characterization, antidiabetic, anticancer, anticholinergic, and molecular docking studies
Mardani_2019_Biotech.Histochem__1 Comparison of the proteome patterns of adipose-derived stem cells with those treated with selegiline using a two dimensional gel electrophoresis analysis
Matozzo_2019_Sci.Rep_9_14302 Ecotoxicological hazard of a mixture of glyphosate and aminomethylphosphonic acid to the mussel Mytilus galloprovincialis (Lamarck 1819)
Matsuda_2019_Neuropsychiatr.Dis.Treat_15_2715 Differentiation Between Dementia With Lewy Bodies And Alzheimer's Disease Using Voxel-Based Morphometry Of Structural MRI: A Multicenter Study
Mo_2019_Bioorg.Chem_93_103310 Design, synthesis, biological evaluation, and molecular modeling studies of quinoline-ferulic acid hybrids as cholinesterase inhibitors
Saouessi_2019_J.Chem.Phys_151_125103 Frequency domain modeling of quasielastic neutron scattering from hydrated protein powders: Application to free and inhibited human acetylcholinesterase
Ueda_2019_Dement.Geriatr.Cogn.Dis.Extra_9_302 Efficacy, Safety, and Tolerability of Switching from Oral Cholinesterase Inhibitors to Rivastigmine Transdermal Patch with 1-Step Titration in Patients with Mild to Moderate Alzheimer's Disease: A 24-Week, Open-Label, Multicenter Study in Japan
Xie_2019_PeerJ_7_e7690 Effects of Lecanicillium lecanii strain JMC-01 on the physiology, biochemistry, and mortality of Bemisia tabaci Q-biotype nymphs
Xu_2019_Ecotoxicol.Environ.Saf_185_109735 Candidate detoxification-related genes in brown planthopper, Nilaparvata lugens, in response to beta-asarone based on transcriptomic analysis
Zhou_2019_Bioorg.Chem_93_103322 Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine N-benzylpiperidine fragments
Almeida_2019_Ecotoxicol.Environ.Saf_186_109760 Biochemical and behavioral responses of zebrafish embryos to magnetic graphene\/nickel nanocomposites
Brignot_2019_Arch.Oral.Biol_108_104550 Oral lipolysis and its association with diet and the perception and digestion of lipids: A systematic literature review
Cai_2019_Bioorg.Chem_93_103328 New 4-N-phenylaminoquinoline derivatives as antioxidant, metal chelating and cholinesterase inhibitors for Alzheimer's disease
Cao_2019_Aquat.Toxicol_214_105253 Exposure to diclofop-methyl induces immunotoxicity and behavioral abnormalities in zebrafish embryos
Codony_2019_Bioorg.Med.Chem_27_115078 Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors
Correia_2019_Chemosphere_235_1022 Behavioral effects in adult zebrafish after developmental exposure to carbaryl
da Rosa_2019_Microb.Pathog__103787 Impacts of Escherichia coli infection in young breeder chicks on the behavior and cerebral activity of purinergic and cholinergic enzymes involved in the regulation of molecules with neurotransmitter and neuromodulator function
De Simone_2019_J.Pharm.Biomed.Anal_178_112899 Advanced analytical methodologies in Alzheimer's disease drug discovery
Deveci_2019_J.Food.Biochem__e13074 Isolation, characterization, and bioactivities of compounds from Fuscoporia torulosa mushroom
Deveci_2019_J.Food.Biochem__e13078 Phytochemical contents, antioxidant effects, and inhibitory activities of key enzymes associated with Alzheimer's disease, ulcer, and skin disorders of Sideritis albiflora and Sideritis leptoclada
El-Mehi_2019_Ann.Anat__151428 Controlled ozone therapy modulates the neurodegenerative changes in the frontal cortex of the aged albino rat
Huang_2019_Molecules_24_ Two New AChE Inhibitors Isolated from Li Folk Herb Heilaohu Kadsura coccinea Stems
Jasiecki_2019_Biomolecules_9_ Butyrylcholinesterase Protein Ends in the Pathogenesis of Alzheimer's Disease-Could BCHE Genotyping Be Helpful in Alzheimer's Therapy?
Jeong_2019_R.Soc.Open.Sci_6_190414 Theoretical study on the toxicity of 'Novichok' agent candidates
Kapeleka_2019_J.Environ.Public.Health_2019_3084501 Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania
Ke_2019_PLoS.Negl.Trop.Dis_13_e0007740 Molluscicidal activity and physiological toxicity of quaternary benzo[c]phenanthridine alkaloids (QBAs) from Macleaya cordata fruits on Oncomelania hupensis
Khuanjing_2019_Acta.Physiol.(Oxf)__e13396 The Effects of Acetylcholinesterase Inhibitors on the Heart in Acute Myocardial Infarction and Heart Failure: From Cells to Patient Reports
Kitagawa_2019_Biomolecules_9_ In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon
Li_2019_Ecotoxicol.Environ.Saf_186_109776 Effects of low concentrations of triphenyltin on neurobehavior and the thyroid endocrine system in zebrafish
Lien_2019_J.Cell.Mol.Med_23_6611 The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux
Moliner_2019_J.Food.Drug.Anal_27_849 Viola cornuta and Viola x wittrockiana: Phenolic compounds, antioxidant and neuroprotective activities on Caenorhabditis elegans
Obara_2019_Pharmacology__1 Sustainable Effects of Distigmine Bromide on Urinary Bladder Contractile Function
Ohno_2019_Front.Pharmacol_10_1045 Antipsychotic Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD): Management of Extrapyramidal Side Effects
Olsvik_2019_Front.Genet_10_794 Effects of Agricultural Pesticides in Aquafeeds on Wild Fish Feeding on Leftover Pellets Near Fish Farms
Perneczky_2019_Dialogues.Clin.Neurosci_21_43 Dementia treatment versus prevention
Qi_2019_Zhongguo.Zhong.Yao.Za.Zhi_44_3213 [Isolation and identification of endophytic fungi from Huperzia serrata and their metabolites' inhibitory activities against acetylcholinesterase and anti-inflammatory activities]
Severcan_2019_Clin.Exp.Hepatol_5_237 Acute effects of different doses of malathion on the rat liver
Shadnia_2019_Arch.Acad.Emerg.Med_7_e46 Atropine Challenge Test in Screening the Organophosphorus Poisoning Cases with Atypical Presentation\; a Brief Report
Thuphairo_2019_Prev.Nutr.Food.Sci_24_327 Bioactive Compounds, Antioxidant Activity and Inhibition of Key Enzymes Relevant to Alzheimer's Disease from Sweet Pepper (Capsicum annuum) Extracts
Verdin-Betancourt_2019_Sci.Rep_9_14758 In vitro inhibition of human red blood cell acetylcholinesterase (AChE) by temephos-oxidized products
Wong_2019_EXCLI.J_18_764 Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells
Zhao_2019_J.Hazard.Mater_384_121358 Self-reduction bimetallic nanoparticles on ultrathin MXene nanosheets as functional platform for pesticide sensing
Zhu_2019_J.Integr.Neurosci_18_327 Current anti-Alzheimer's disease effect of natural products and their principal targets
Makhaeva_2019_Russ Chem Bull_68_967 Cholinesterase and carboxylesterase inhibitors as pharmacological agents
Perez_2019_Recent.Adv.in.White.Biotechnol.Through.Fungi__361 Fungal Lipases: Versatile Tools for White Biotechnology
Ado_2019_Nat.Prod.Res__1 Acetylcholinesterase and alpha-glucosidase inhibitory compounds from Callicarpa maingayi
Arvanitakis_2019_JAMA_322_1589 Diagnosis and Management of Dementia: Review
Bastiaensen_2019_Chemosphere_236_124348 Towards establishing indicative values for metabolites of organophosphate ester contaminants in human urine
Caprari_2019_J.Biomol.Struct.Dyn__1 Uncovering the structure and function of Pseudomonas aeruginosa periplasmic proteins by an in silico approach
Cerasoli_2019_Biochem.Pharmacol__113670 Butyrylcholinesterase, a stereospecific in vivo bioscavenger against nerve agent intoxication
Dahms-Verster_2019_Environ.Toxicol.Pharmacol_73_103272 Biochemical responses revealed in an amphibian species after exposure to a forgotten contaminant: An integrated biomarker assessment
Gowayed_2019_Biochem.Pharmacol__113665 The role of alpha7nAChR in controlling the anti-inflammatory\/anti-arthritic action of Galantamine
Grella_2019_Food.Chem_307_125523 Influence of nanoencapsulated lutein on acetylcholinesterase activity: In vitro determination, kinetic parameters, and in silico docking simulations
Hepnarova_2019_Toxicol.Appl.Pharmacol__114776 Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators
Jankowska_2019_Molecules_24_ Menthol Increases Bendiocarb Efficacy Through Activation of Octopamine Receptors and Protein Kinase A
Janockova_2019_J.Enzyme.Inhib.Med.Chem_34_877 In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers
Kanda_2019_BMC.Surg_19_143 Feasibility of subtotal esophagectomy with systematic lymphadenectomy in selected elderly patients with esophageal cancer\; a propensity score matching analysis
Kozachok_2019_Phytochemistry_169_112162 Reinvestigation of Herniaria glabra L. saponins and their biological activity
Liu_2019_Fitoterapia__104366 Anti-cholinesterase activities of constituents isolated from Lycopodiastrum casuarinoides
Majima_2019_J.Nutr.Sci.Vitaminol.(Tokyo)_65_S104 Biological Functions of alpha-Tocopheryl Succinate
Naz_2019_Drug.Des.Devel.Ther_13_3485 Enzyme Inhibitory, Antioxidant And Antibacterial Potentials Of Synthetic Symmetrical And Unsymmetrical Thioureas
Park_2019_Antioxidants.(Basel)_8_ Anti-Oxidant Activity of Gallotannin-Enriched Extract of Galla Rhois Can Associate with the Protection of the Cognitive Impairment through the Regulation of BDNF Signaling Pathway and Neuronal Cell Function in the Scopolamine-Treated ICR Mice
Pellis_2019_Methods.Enzymol_627_23 Integrating computational and experimental methods for efficient biocatalytic synthesis of polyesters
Perez-Fernandez_2019_Food.Chem.Toxicol__110865 Long-term effects of low doses of Chlorpyrifos exposure at the preweaning developmental stage: A locomotor, pharmacological, brain gene expression and gut microbiome analysis
Rodriguez-Soacha_2019_Eur.J.Med.Chem_180_690 Multi-target-directed-ligands acting as enzyme inhibitors and receptor ligands
Romero_2019_J.Pharm.Biomed.Anal_178_112909 HPTLC based approach for bioassay-guided evaluation of antidiabetic and neuroprotective effects of eight essential oils of the Lamiaceae family plants
Sadeer_2019_Antioxidants.(Basel)_8_ Untargeted Metabolomic Profiling, Multivariate Analysis and Biological Evaluation of the True Mangrove (Rhizophora mucronata Lam.)
Shahbaaz_2019_J.Biomol.Struct.Dyn__1 The structural basis of acid resistance in Mycobacterium tuberculosis: Insights from multiple pH regime molecular dynamics simulations
Viespe_2019_Sensors.(Basel)_19_ Love Wave Surface Acoustic Wave Sensor with Laser-Deposited Nanoporous Gold Sensitive Layer
Xu_2019_Eur.J.Med.Chem_180_656 Triazole derivatives as inhibitors of Alzheimer's disease: Current developments and structure-activity relationships
Yiannopoulou_2019_Case.Rep.Nephrol.Dial_9_126 Donepezil Treatment for Alzheimer's Disease in Chronic Dialysis Patients
Yuan_2019_BMC.Neurol_19_236 Augmentation of peripheral lymphocyte-derived cholinergic activity in patients with acute ischemic stroke
Buryska_2019_Anal.Chem_91_10008 Controlled Oil\/Water Partitioning of Hydrophobic Substrates Extending the Bioanalytical Applications of Droplet-Based Microfluidics
Enz_2019_Pharmacol.Ther_198_135 CD26\/DPP4 - a potential biomarker and target for cancer therapy
Griswold_2019_Cell.Chem.Biol_26_901 A Chemical Strategy for Protease Substrate Profiling
Sriramachandran_2019_Nat.Commun_10_3678 Arkadia\/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2\/3 chain
Deng_2019_Bioorg.Chem__103366 Optimization of the benzamide fragment targeting the S2' site leads to potent dipeptidyl peptidase-IV inhibitors
Fawzi_2019_Behav.Brain.Res__112314 Deferiprone ameliorates memory impairment in Scopolamine-treated rats: the impact of its iron-chelating effect on beta-amyloid disposition
Khudina_2019_Bioorg.Med.Chem.Lett__126716 Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers
Pinto_2019_Parasit.Vectors_12_494 Susceptibility to insecticides and resistance mechanisms in three populations of Aedes aegypti from Peru
Sine_2019_Biomarkers__1 Serum Cholinesterase biomarker study in farmers - Souss Massa Region-, Morocco: case-control study
Abd El-Rahman_2019_Aquat.Toxicol_217_105329 Assessment of hematological, hepato-renal, antioxidant, and hormonal responses of Clarias gariepinus exposed to sub-lethal concentrations of oxyfluorfen
Arianna_2019_Exp.Gerontol__110754 Erythrocyte membrane fluidity in mild cognitive impairment and Alzheimer's disease patients
Bhattacharjee_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108626 Quercetin-induced amelioration of deltamethrin stress in freshwater teleost, Channa punctata: Multiple biomarker analysis
Chen_2019_J.Clin.Med_8_ Serum Level and Activity of Butylcholinesterase: A Biomarker for Post-Stroke Dementia
Deng_2019_Cancer.Cell.Int_19_273 Role of XIAP gene overexpressed bone marrow mesenchymal stem cells in the treatment of cerebral injury in rats with cerebral palsy
Faustino_2019_Molecules_24_ Puccinellia maritima, Spartina maritime, and Spartina patens Halophytic Grasses: Characterization of Polyphenolic and Chlorophyll Profiles and Evaluation of Their Biological Activities
Fenoy_2019_Biosens.Bioelectron_148_111796 Acetylcholine biosensor based on the electrochemical functionalization of graphene field-effect transistors
Guedes_2019_Molecules_24_ Bioactivities of Centaurium erythraea (Gentianaceae) Decoctions: Antioxidant Activity, Enzyme Inhibition and Docking Studies
Jaouadi_2019_Antioxidants.(Basel)_8_ Differentiation of Phenolic Composition Among Tunisian Thymus algeriensis Boiss. et Reut. (Lamiaceae) Populations: Correlation to Bioactive Activities
Lee_2019_BMC.Cancer_19_1016 Dipeptidyl-peptidase-4 (DPP-4) inhibitor ameliorates 5-flurouracil induced intestinal mucositis
Moretto_2019_Cell.Rep_29_1130 TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering
Moricz_2019_J.Chromatogr.A__460602 Distinction and valorization of 30 root extracts of five goldenrod (Solidago) species
Ravi_2019_Pharmacol.Rep_71_1151 Cassia tora prevents Abeta1-42 aggregation, inhibits acetylcholinesterase activity and protects against Abeta1-42-induced cell death and oxidative stress in human neuroblastoma cells
Sooksai_2019_3.Biotech_9_389 Production of cutinase from Fusarium falciforme and its application for hydrophilicity improvement of polyethylene terephthalate fabric
Tian_2019_J.Food.Biochem__e13088 Chemical characterization of main bioactive constituents in Paeonia ostii seed meal and GC-MS analysis of seed oil
Bajda_2019_Eur.J.Med.Chem_185_111785 Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands
Bak_2019_Int.J.Mol.Sci_20_5385 SAR-mediated Similarity Assessment of the Property Profile for New, Silicon-Based AChE\/BChE Inhibitors
Erukainure_2019_J.Ethnopharmacol__112358 Buddleja saligna Willd (Loganiaceae) inhibits angiotensin-converting enzyme activity in oxidative cardiopathy with concomitant modulation of nucleotide hydrolyzing enzymatic activities and dysregulated lipid metabolic pathways
Figueiredo_2019_Front.Mol.Biosci_6_109 Enzymatic Polymerization of PCL-PEG Co-polymers for Biomedical Applications
Gado_2019_Bioorg.Chem__103353 Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system
Karami_2019_Front.Mol.Neurosci_12_239 CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer's Disease
Kashyap_2019_Steroids__108529 Sarsasapogenin: A steroidal saponin from Asparagus racemosus as multi target directed ligand in Alzheimer's Disease
Kaur_2019_Int.J.Med.Mushrooms_21_755 Bioactivity-Guided Isolation of Acetylcholinesterase Inhibitor from Ganoderma mediosinense (Agaricomycetes)
Kokturk_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_227_108636 The effects of n-butanol on oxidative stress and apoptosis in zebra fish (Danio rerio) larvae
Lan_2019_Bioorg.Chem__103388 Detection techniques of carboxylesterase activity: An update review
Liang_2019_Biosens.Bioelectron_148_111825 Displaying of acetylcholinesterase mutants on surface of yeast for ultra-trace fluorescence detection of organophosphate pesticides with gold nanoclusters
Mancini_2019_Parkinsonism.Relat.Disord_69_40 Effects of augmenting cholinergic neurotransmission on balance in Parkinson's disease
Naqvi_2019_Pak.J.Pharm.Sci_32_1893 Curcumin lessens unpredictable chronic mild stress-induced depression and memory deficits by modulating oxidative stress and cholinergic activity
Ozcelik_2019_Pharmacol.Rep_71_1253 A new series of pyridazinone derivatives as cholinesterases inhibitors: Synthesis, in vitro activity and molecular modeling studies
Ramos_2019_J.Biomol.Struct.Dyn__1 Potential inhibitors of the enzyme acetylcholinesterase and juvenile hormone with insecticidal activity: study of the binding mode via docking and molecular dynamics simulations
Savateev_2019_Eur.J.Med.Chem_185_111808 Nitrothiadiazolo[3,2-a]pyrimidines as promising antiglycating agents
Semenov_2019_Eur.J.Med.Chem_185_111787 6-Methyluracil derivatives as peripheral site ligand-hydroxamic acid conjugates: Reactivation for paraoxon-inhibited acetylcholinesterase
Silvia_2019_Environ.Toxicol.Pharmacol_73_103280 Evaluation of endocrine disruption and gestational disorders in women residing in areas with intensive pesticide application: An exploratory study
Tenfen_2019_Nat.Prod.Res__1 Phenolic profile by HPLC-ESI-MS\/MS of six Brazilian Eugenia species and their potential as cholinesterase inhibitors
Theleritis_2019_Front.Pharmacol_10_1108 Unmet Needs in Pharmacological Treatment of Apathy in Alzheimer's Disease: A Systematic Review
Turkan_2019_Bioorg.Chem__103333 ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn
Amornlertwatana_2019_J.Med.Case.Rep_13_327 Heroin overdose masquerades as methomyl poisoning: a case report
Badaoui_2019_Nat.Prod.Res__1 Pyrroloquinolone A, a new alkaloid and other phytochemicals from Atractylis cancellata L. with antioxidant and anticholinesterase activities
Bernal-Rey_2019_Ecotoxicol.Environ.Saf_187_109673 Seasonal variations in the dose-response relationship of acetylcholinesterase activity in freshwater fish exposed to chlorpyrifos and glyphosate
Borrero_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108664 Insecticide design using in silico and in vivo analysis of different pharmacological targets in Aedes aegypti
Chen_2019_J.Ginseng.Res_43_499 Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments
Chen_2019_Theranostics_9_7359 Carboxylesterase-Cleavable Biotinylated Nanoparticle for Tumor-Dual Targeted Imaging
Eskandari_2019_Heliyon_5_e02426 Synthesis, and molecular modeling of bis(3-(piperazine-1-yl)propyl)tungstate (BPPT) nanoparticles, and its first catalytic application for one-pot synthesis of 4H-chromene derivatives
Fan_2019_Adv.Mater__e1905785 Challenges in Fluorescence Detection of Chemical Warfare Agent Vapors Using Solid-State Films
Fu_2019_Anal.Chim.Acta_1092_126 Ambient light sensor based colorimetric dipstick reader for rapid monitoring organophosphate pesticides on a smart phone
Jamali-Raeufy_2019_J.Chem.Neuroanat_102_101709 Isorhamnetin exerts neuroprotective effects in STZ-induced diabetic rats via attenuation of oxidative stress, inflammation and apoptosis
Jia_2019_Bioelectrochemistry_131_107392 Acetylcholinesterase modified AuNPs-MoS2-rGO\/PI flexible film biosensor: Towards efficient fabrication and application in paraoxon detection
Jin_2019_Sci.Total.Environ_700_134495 Toxic effects of fluridone on early developmental stages of Japanese Medaka (Oryzias latipes)
Kim_2019_BMC.Complement.Altern.Med_19_291 Anti-inflammatory effect of Vaccinium oldhamii stems through inhibition of NF-kappaB and MAPK\/ATF2 signaling activation in LPS-stimulated RAW264.7 cells
Kratky_2019_Biomolecules_9_ 2-Hydroxy-N-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase
Lajmanovich_2019_Heliyon_5_e02601 First evaluation of novel potential synergistic effects of glyphosate and arsenic mixture on Rhinella arenarum (Anura: Bufonidae) tadpoles
Ling_2019_Molecules_24_ Asatone and Isoasatone A Against Spodoptera litura Fab. by Acting on Cytochrome P450 Monoxygenases and Glutathione Transferases
Liu_2019_PLoS.One_14_e0224657 Three-dimensional (3D) brain microphysiological system for organophosphates and neurochemical agent toxicity screening
Liu_2019_Zhonghua.Yi.Xue.Za.Zhi_99_3221 [Distribution characteristics and correlation analysis of antibody detection value in myasthenia gravis]
Macierzanka_2019_Adv.Colloid.Interface.Sci_274_102045 Bile salts in digestion and transport of lipids
Mphahlele_2019_Int.J.Mol.Sci_20_ In Vitro Evaluation and Docking Studies of 5-oxo-5H-furo[3,2-g]chromene-6-carbaldehyde Derivatives as Potential Anti-Alzheimer's Agents
Quartinello_2019_Front.Chem_7_685 Increased Flame Retardancy of Enzymatic Functionalized PET and Nylon Fabrics via DNA Immobilization
Thi_2019_Sci.Rep_9_16152 Isolation of endophytic fungi and screening of Huperzine A-producing fungus from Huperzia serrata in Vietnam
Ul Bari_2019_Drug.Des.Devel.Ther_13_3029 Isolation, pharmacological evaluation and molecular docking studies of bioactive compounds from Grewia optiva
Williams_2019_Bioorg.Med.Chem.Lett__126754 Discovery of potent and selective butyrylcholinesterase inhibitors through the use of pharmacophore-based screening
Youssif_2019_PLoS.One_14_e0223781 Anti-Alzheimer potential, metabolomic profiling and molecular docking of green synthesized silver nanoparticles of Lampranthus coccineus and Malephora lutea aqueous extracts
Zafar_2019_BMC.Complement.Altern.Med_19_296 Isolation of bioactive compounds from Bergenia ciliata (haw.) Sternb rhizome and their antioxidant and anticholinesterase activities
Adedara_2019_Environ.Toxicol.Pharmacol_73_103294 Neurobehavioural and biochemical responses associated with exposure to binary waterborne mixtures of zinc and nickel in rats
Bachmann_2019_Invest.Ophthalmol.Vis.Sci_60_4759 IPL Sublamination in Chicken Retinal Spheroids Is Initiated via Muller Cells and Cholinergic Differentiation, and Is Disrupted by NMDA Signaling
Celik_2019_Neurotoxicol_76_126 Morin attenuates ifosfamide-induced neurotoxicity in rats via suppression of oxidative stress, neuroinflammation and neuronal apoptosis
Chen_2019_Zootaxa_4568_zootaxa 4568 1 9 Two new species of marine flatworm from southern China facilitate determination of the phylogenetic position of the genus Nerpa Marcus, 1948 and the histochemical structure of the nervous system in the genus Paucumara Sluys, 1989 (Platyhelminthes, Tricladida, Maricola)
Clemente_2019_Environ.Sci.Pollut.Res.Int_26_30508 Exploring the mechanisms of graphene oxide behavioral and morphological changes in zebrafish
Espinosa_2019_Plants.(Basel)_8_ Chemical, Enantioselective, and Sensory Analysis of a Cholinesterase Inhibitor Essential Oil from Coreopsis triloba S.F. Blake (Asteraceae)
Fedorova_2019_Neurogastroenterol.Motil__e13759 In vivo positron emission tomography imaging of decreased parasympathetic innervation in the gut of vagotomized patients
Gan_2019_Artif.Cells.Nanomed.Biotechnol_47_4202 Protective effects of phenformin on zebrafish embryonic neurodevelopmental toxicity induced by X-ray radiation
Ge_2019_Int.J.Mol.Sci_20_ Integrative Assessment of Mixture Toxicity of Three Ionic Liquids on Acetylcholinesterase Using a Progressive Approach from 1D Point, 2D Curve, to 3D Surface
Isik_2019_Arch.Physiol.Biochem__1 AChE mRNA expression as a possible novel biomarker for the diagnosis of coronary artery disease and Alzheimer's disease, and its association with oxidative stress
Kapeleka_2019_Int.J.Environ.Health.Res__1 Pesticide exposure and genotoxic effects as measured by DNA damage and human monitoring biomarkers
Kisui_2019_Eur.J.Pharm.Sci__105143 Strain and sex differences in drug hydrolase activities in rodent livers
Li_2019_Nat.Prod.Res__1 Wortmannine H, a phenylpentenol isolated from an endophytic fungus, Talaromyces wortmannii LGT-4
Liang_2019_Sci.Rep_9_16989 Time-Course Changes in Urine Metabolic Profiles of Rats Following 90-Day Exposure to Propoxur
Luque-Martin_2019_Front.Pharmacol_10_1242 Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis
Magnin_2019_ACS.Omega_4_18663 Studies Exploring the Interaction of the Organophosphorus Compound Paraoxon with Fullerenes
Makhaeva_2019_Bioorg.Chem__103387 Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation
Malgas_2019_World.J.Microbiol.Biotechnol_35_187 A mini review of xylanolytic enzymes with regards to their synergistic interactions during hetero-xylan degradation
Montalvan_2019_Plants.(Basel)_8_ Chemical Composition, Enantiomeric Distribution, and Sensory Evaluation of the Essential Oils Distilled from the Ecuadorian Species Myrcianthes myrsinoides (Kunth) Grifo and Myrcia mollis (Kunth) DC. (Myrtaceae)
Moslemi_2019_Behav.Brain.Res__112354 Oxytocin protects against 3-NP induced learning and memory impairment in rats: sex differences in behavioral and molecular responses to the context of prenatal stress
Naumann_2019_Cancers.(Basel)_11_ Cachectic Body Composition and Inflammatory Markers Portend a Poor Prognosis in Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiation
Olasehinde_2019_Mar.Drugs_17_ Macroalgae as a Valuable Source of Naturally Occurring Bioactive Compounds for the Treatment of Alzheimer's Disease
Pifferi_2019_Front.Pharmacol_10_1291 Strengths and Weaknesses of the Gray Mouse Lemur (Microcebus murinus) as a Model for the Behavioral and Psychological Symptoms and Neuropsychiatric Symptoms of Dementia
Retinasamy_2019_Front.Pharmacol_10_1216 Ethanolic Extract of Orthosiphon stamineus Improves Memory in Scopolamine-Induced Amnesia Model
Sathya_2019_Food.Chem.Toxicol__110962 Phytol loaded PLGA nanoparticles regulate the expression of Alzheimer's related genes and neuronal apoptosis against amyloid-beta induced toxicity in Neuro-2a cells and transgenic Caenorhabditis elegans
Tampi_2019_Handb.Clin.Neurol_165_59 Behavioral symptomatology and psychopharmacology of Lewy body dementia
Vergallo_2019_Int.J.Pharm__118826 Design, Synthesis and Characterization of a PEGylated Stanozolol for Potential Therapeutic Applications
Xia_2019_Eur.J.Pharmacol__172809 Neurobehavioral effects of selected tobacco constituents in rodents following subchronic administration
Yoshioka_2019_Molecules_24_ alpha-Glucosidase and Pancreatic Lipase Inhibitory Activities of Diterpenes from Indian Mango Ginger (Curcuma amada Roxb.) and Its Derivatives
Almansour_2019_Bioorg.Med.Chem.Lett__126789 Design, synthesis and cholinesterase inhibitory activity of novel spiropyrrolidine tethered imidazole heterocyclic hybrids
Anesti_2019_Epilepsy.Behav_102_106632 Effect of rutin on anxiety-like behavior and activity of acetylcholinesterase isoforms in specific brain regions of pentylenetetrazol-treated mice
Baldissera_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108674 Diphenyl diselenide dietary supplementation alleviates behavior impairment and brain damage in grass carp (Ctenopharyngodon idella) exposed to methylmercury chloride
Brahma_2019_Ecotoxicol.Environ.Saf__109939 Acute toxicity of lead in fresh water bivalves Lamellidens jenkinsianus obesa and Parreysia (Parreysia) corrugata with evaluation of sublethal effects on acetylcholinesterase and catalase activity, lipid peroxidation, and behavior
Cahlikova_2019_Molecules_24_ The Genus Nerine Herb. (Amaryllidaceae): Ethnobotany, Phytochemistry, and Biological Activity
Cai_2019_AAPS.J_22_5 Reengineering of Albumin-Fused Cocaine Hydrolase CocH1 (TV-1380) to Prolong Its Biological Half-Life
Cao_2019_Ecotoxicol.Environ.Saf__109954 A comparative study of acetylcholinesterase and general-esterase activity assays using different substrates, in vitro and in vivo exposures and model organisms
Cao_2019_Nat.Prod.Res__1 Two new phenylpropanoids and a new dihydrostilbenoid from the flower buds of Magnolia biondii pamp and their acetylcholinesterase inhibitory activities
Chetoui_2019_Drug.Chem.Toxicol__1 Exposure of Mactra corallina to acute doses of lead: effects on redox status, fatty acid composition and histomorphological aspect
Contreras-Aguilar_2019_Animals.(Basel)_9_ Changes in Saliva Analytes Correlate with Horses' Behavioural Reactions to An Acute Stressor: A Pilot Study
Deb_2019_Ecotoxicol.Environ.Saf__109988 Bioactivity and efficacy of essential oils extracted from Artemisia annua against Tribolium casteneum (Herbst. 1797) (Coleoptera: Tenebrionidae): An eco-friendly approach
DeVito_2019_J.Subst.Abuse.Treat_107_29 Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder
Ding_2019_Biosens.Bioelectron__111867 Ultrasensitive and visible light-responsive photoelectrochemical aptasensor for edifenphos based on Zinc phthalocyanine sensitized MoS2 nanosheets
Fernandez-Poyatos_2019_Molecules_24_ Phenolic Characterization, Antioxidant Activity, and Enzyme Inhibitory Properties of Berberis thunbergii DC. Leaves: A Valuable Source of Phenolic Acids
Gobaru_2019_Am.J.Case.Rep_20_1709 Human Leukocyte Antigen (HLA) Subtype-Dependent Development of Myasthenia Gravis, Type-1 Diabetes Mellitus, and Hashimoto Disease: A Case Report of Autoimmune Polyendocrine Syndrome Type 3
Gupta_2019_PLoS.One_14_e0225188 Adeno-associated virus-mediated expression of human butyrylcholinesterase to treat organophosphate poisoning
He_2019_Biosens.Bioelectron__111898 Coreactant-free electrochemiluminescence biosensor for the determination of organophosphorus pesticides
Kaur_2019_J.Nutr.Biochem_76_108255 Involvement of the nitric oxide signaling in modulation of naringin against intranasal manganese and intracerbroventricular beta-amyloid induced neurotoxicity in rats
Luo_2019_Bioorg.Med.Chem__115190 Synthesis, in vitro and in vivo biological evaluation of novel graveolinine derivatives as potential anti-Alzheimer agents
Mphahlele_2019_Biomolecules_9_ Exploring Biological Activity of 4-Oxo-4H-furo[2,3-h]chromene Derivatives as Potential Multi-Target-Directed Ligands Inhibiting Cholinesterases, beta-Secretase, Cyclooxygenase-2, and Lipoxygenase-5\/15
Ochiishi_2019_Sci.Rep_9_17368 New Alzheimer's disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid beta oligomers
Panthong_2019_Nat.Prod.Res__1 Amabiloid A from Crinum x amabile Donn ex Ker Gawl
Parvaz_2019_Life.Sci__117099 A brief survey on the advanced brain drug administration by nanoscale carriers: With a particular focus on AChE reactivators
Pecio_2019_Molecules_24_ Yuccalechins A-C from the Yucca schidigera Roezl ex Ortgies Bark: Elucidation of the Relative and Absolute Configurations of Three New Spirobiflavonoids and Their Cholinesterase Inhibitory Activities
Sharma_2019_Toxicol.Rep_6_1164 Neuroprotective potential of solanesol in intracerebroventricular propionic acid induced experimental model of autism: Insights from behavioral and biochemical evidence
Vargas-Mendez_2019_Saudi.J.Biol.Sci_26_1613 Bioactivity of semisynthetic eugenol derivatives against Spodoptera frugiperda (Lepidoptera: Noctuidae) larvae infesting maize in Colombia
Wu_2019_Exp.Neurol__113128 microRNA-592 blockade inhibits oxidative stress injury in Alzheimer's disease astrocytes via the KIAA0319-mediated Keap1\/Nrf2\/ARE signaling pathway
Zhou_2019_Molecules_24_ Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations
Abis_2019_Anal.Chem_91_14865 Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase
Ali-Shtayeh_2019_Evid.Based.Complement.Alternat.Med_2019_3834265 Biological Properties and Bioactive Components of Mentha spicata L. Essential Oil: Focus on Potential Benefits in the Treatment of Obesity, Alzheimer's Disease, Dermatophytosis, and Drug-Resistant Infections
Ambartsumyan_2019_Pediatr.Dev.Pathol__1093526619892351 Diagnosis of Hirschsprung Disease
Azuma_2019_Circ.Cardiovasc.Interv_12_e008015 Predictive Model for Mortality Risk Including the Wound, Ischemia, Foot Infection Classification in Patients Undergoing Revascularization for Critical Limb Ischemia
Bal_2019_Bioorg.Chem__103468 Novel 2-methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties
Bolognino_2019_Molecules_24_ A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer's Disease
Dionisio_2019_Environ.Toxicol.Pharmacol_74_103295 Multi-parametric analysis of ciprofloxacin toxicity at ecologically relevant levels: Short- and long-term effects on Daphnia magna
Foyet_2019_Evid.Based.Complement.Alternat.Med_2019_4568401 Anticholinesterase and Antioxidant Potential of Hydromethanolic Extract of Ziziphus mucronata (Rhamnaceae) Leaves on Scopolamine-Induced Memory and Cognitive Dysfunctions in Mice
Genc Bilgicli_2019_Arch.Pharm.(Weinheim)__e1900304 Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl-based 4-thiazolidinone derivatives
Hu_2019_Exp.Ther.Med_18_4388 Ginseng berry aqueous extract prevents scopolamine-induced memory impairment in mice
Lan_2019_Bioorg.Chem__103413 Design, synthesis and evaluation of novel ferulic acid derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease
Lucero_2019_Biomed.Res.Int_2019_7901760 Validity and Reliability of an Assessment Tool for the Screening of Neurotoxic Effects in Agricultural Workers in Chile
Mitton_2019_Ecotoxicol.Environ.Saf__109917 Impacts of dietary supplementation with p-coumaric acid and indole-3-acetic acid on survival and biochemical response of honey bees treated with tau-fluvalinate
Naguib_2019_Neurobiol.Dis__104695 Galantamine protects against synaptic, axonal, and vision deficits in experimental neurotrauma
Padnya_2019_Bioorg.Chem__103455 Water-soluble betaines and amines based on thiacalix[4]arene scaffold as new cholinesterase inhibitors
Paranavitane_2019_J.Med.Case.Rep_13_348 Thymoma complicated with myasthenia gravis and Good syndrome - a therapeutic conundrum: a case report
Park_2019_Sci.Rep_9_18080 Inhibitory characteristics of flavonol-3-O-glycosides from Polygonum aviculare L. (common knotgrass) against porcine pancreatic lipase
Wang_2019_Br.J.Nutr__1 Protective effects of enzyme degradation extract from Porphyra yezoensis against oxidative stress and brain injury in D-galactose-induced aging mice
Wojdylo_2019_Plants.(Basel)_8_ Polyphenol Compounds and Biological Activity of Caper (Capparis spinosa L.) Flowers Buds
Abbasi_2019_Pak.J.Pharm.Sci_32_2003 In vitro assessment of antibacterial, antifungal, enzyme inhibition and hemolytic activities of various fractions of Rhynchosia pseudo-cajan
Afzali_2019_Caspian.J.Intern.Med_10_458 Butyrylcholinesterase level in poisoned patients with phosphide compounds
Brehm_2019_Neurosci.Lett_713_134503 Zebrafish neuromuscular junction: The power of N
Deng_2019_Pak.J.Pharm.Sci_32_2091 Design, synthesis and biological Evaluation of Dual acetyl cholinesterase and beta-secretase inhibitors in treatment for alzheimer's Disease
Halff_2019_Cell.Rep_29_2599 SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling
Jiang_2019_Int.J.Nanomedicine_14_9217 The Optimization Design Of Lactoferrin Loaded HupA Nanoemulsion For Targeted Drug Transport Via Intranasal Route
Joe_2019_BMJ_367_l6217 Cognitive symptoms of Alzheimer's disease: clinical management and prevention
Ling_2019_Clin.Neurol.Neurosurg_189_105620 Distribution characteristics of sweat gland nerve fibres in normal humans identified by acetylcholinesterase histochemical staining
Martinez-Mendez_2019_IBRO.Rep_7_108 Bilateral enucleation at birth modifies calcium spike amplitude, but not frequency, in neurons of the somatosensory thalamus and cortex: Implications for developmental cross-modal plasticity
Montaser_2019_Oxid.Med.Cell.Longev_2019_3528148 Astrocyte-Targeted Transporter-Utilizing Derivatives of Ferulic Acid Can Have Multifunctional Effects Ameliorating Inflammation and Oxidative Stress in the Brain
Ozcelikay_2019_Polymers.(Basel)_11_ Electrochemical MIP Sensor for Butyrylcholinesterase
Pagliara_2019_Biomolecules_9_ Lemon Peel Polyphenol Extract Reduces Interleukin-6-Induced Cell Migration, Invasiveness, and Matrix Metalloproteinase-9\/2 Expression in Human Gastric Adenocarcinoma MKN-28 and AGS Cell Lines
Parthiban_2019_Ecotoxicol.Environ.Saf_189_110050 Annona muricata: An alternate mosquito control agent with special reference to inhibition of detoxifying enzymes in Aedes aegypti
Paskus_2019_Cell.Rep_29_2944 Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action
Rosa_2019_Bull.Entomol.Res__1 Bioactivity of some Apiaceae essential oils and their constituents against Sitophilus zeamais (Coleoptera: Curculionidae)
Santarpia_2019_Nutrients_11_ Nutritional Rehabilitation in Patients with Malnutrition Due to Crohn's Disease
Shrestha_2019_Molecules_24_ Phytochemical Fingerprinting and In Vitro Bioassays of the Ethnomedicinal Fern Tectaria coadunata (J. Smith) C. Christensen from Central Nepal
Singh_2019_Drug.Dev.Ind.Pharm__1 Inorganic clay nanocomposite system for improved cholinesterase inhibition and brain pharmacokinetics of donepezil
Tesser_2019_Sci.Total.Environ__135332 Sublethal effects of waterborne copper and copper nanoparticles on the freshwater Neotropical teleost Prochilodus lineatus: A comparative approach
Tian_2019_Bioorg.Chem__103477 Flurbiprofen-chalcone hybrid Mannich base derivatives as balanced multifunctional agents against Alzheimer's disease: Design, synthesis and biological evaluation
Wichur_2019_Eur.J.Med.Chem_187_111916 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease
Wu_2019_Neuropsychiatr.Dis.Treat_15_3167 Traditional Chinese Medicine Shenmayizhi Decoction Ameliorates Memory And Cognitive Impairment Induced By Scopolamine Via Preventing Hippocampal Cholinergic Dysfunction In Rats
Yagi_2019_J.Food.Biochem__e13107 Chemical profile, antiproliferative, antioxidant, and enzyme inhibition activities and docking studies of Cymbopogon schoenanthus (L.) Spreng. and Cymbopogon nervatus (Hochst.) Chiov. from Sudan
Yao_2019_Nat.Prod.Res__1 Alkaloids with acetylcholinesterase inhibitory activity from Corydalis racemosa (Thunb.) Pers
Zindler_2019_Ecotoxicol.Environ.Saf_186_109754 Analysis of tail coiling activity of zebrafish (Danio rerio) embryos allows for the differentiation of neurotoxicants with different modes of action
Opris_2019_Front.Syst.Neurosci_13_69 Activation of Brainstem Neurons During Mesencephalic Locomotor Region-Evoked Locomotion in the Cat
Abd-Elhakim_2019_Food.Chem.Toxicol__111055 Camel milk rescues neurotoxic impairments induced by fenpropathrin via regulating oxidative stress, apoptotic, and inflammatory events in the brain of rats
Barboza_2019_Sci.Total.Environ__134625 Microplastics in wild fish from North East Atlantic Ocean and its potential for causing neurotoxic effects, lipid oxidative damage, and human health risks associated with ingestion exposure
Cetin_2019_Toxicol.Rep_6_1273 Anticholinergic and antioxidant activities of usnic acid-an activity-structure insight
Chebotareva_2019_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_119_56 [The use of donepezil in gait disorders in eldery patients with dementia]
Dalmolin_2019_Environ.Toxicol.Pharmacol_75_103304 Biomarkers of occupational exposure to pesticides: Systematic review of insecticides
Levin_2019_Zh.Nevrol.Psikhiatr.Im.S.S.Korsakova_119_10 [Predementia neurocognitive impairment in the elderly]
Mahomoodally_2019_Food.Chem.Toxicol__111052 Utilisation of Rhododendron luteum Sweet bioactive compounds as valuable source of enzymes inhibitors, antioxidant, and anticancer agents
Matysiak_2019_Biomolecules_9_ Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1H- Benzimidazole Analogues
Nassar_2019_Sci.Total.Environ__135228 Considerations for cholinesterase biomonitoring in flower and ornamental plant greenhouse workers
Pullaguri_2019_Environ.Toxicol.Pharmacol_75_103311 Triclosan alters adult zebrafish behavior and targets acetylcholinesterase activity and expression
Rocchetti_2019_Antioxidants.(Basel)_8_ Chemical Profiling and Biological Properties of Extracts from Different Parts of Colchicum Szovitsii Subsp. Szovitsii
Rullo_2019_Molecules_24_ Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones
Saliu_2019_Drug.Chem.Toxicol__1 Modulatory effects of stonebreaker (Phyllanthus amarus) and bitter gourd (Momordica charantia) on enzymes linked with cardiac function in heart tissue of doxorubicin-stressed rats
Severo_2019_Ecotoxicol.Environ.Saf_190_110071 Ecological risk of pesticide contamination in a Brazilian river located near a rural area: A study of biomarkers using zebrafish embryos
Shi_2020_Int.J.Biol.Macromol_144_183 Enzymatic hydrolysis of polyester: Degradation of poly(epsilon-caprolactone) by Candida antarctica lipase and Fusarium solani cutinase
Shih_2019_Eur.J.Pharmacol__172851 Differential blockade by huperzine A and donepezil of sympathetic nicotinic acetylcholine receptor-mediated nitrergic neurogenic dilations in porcine basilar arteries
Swetha_2019_Future.Med.Chem_11_3161 Multifunctional hybrid sulfonamides as novel therapeutic agents for Alzheimer's disease
Tantawy_2019_Bioorg.Chem__103464 The larvicidal activity of natural inspired piperine-based dienehydrazides against Culex pipiens
Taylor_2019_BMC.Neurol_19_326 The effects of repetitive transcranial magnetic stimulation in older adults with mild cognitive impairment: a protocol for a randomized, controlled three-arm trial
Vaucher_2019_Restor.Neurol.Neurosci_37_553 Cholinergic potentiation of visual perception and vision restoration in rodents and humans
Wang_2019_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_37_815 [Effects on the respiration and nervous system of rat exposed to the thermobaric bomb simulated gas]
Yang_2019_Int.J.Mol.Sci_20_ Comparing and Contrasting the Multiple Roles of Butenolide Plant Growth Regulators: Strigolactones and Karrikins in Plant Development and Adaptation to Abiotic Stresses
Zhang_2019_Antiviral.Res__104693 Safety, efficacy, and pharmacokinetics of pradefovir for the treatment of chronic hepatitis B infection
Acet_2019_J.Food.Biochem__e13128 An assessment of phenolic profiles, fatty acid compositions, and biological activities of two Helichrysum species: H. plicatum and H. chionophilum
Ahmad_2019_Drug.Des.Devel.Ther_13_4185 Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH\/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies
Akdeniz_2019_J.Food.Biochem__e13124 Phytochemical and biological investigations on two Nepeta species: Nepeta heliotropifolia and N. congesta subsp. cryptantha
Aswani_2019_Sci.Rep_9_19762 Biochemical adaptation in brain Acetylcholinesterase during acclimation to sub-lethal temperatures in the eurythermal fish Tilapia mossambica
Bernieri_2019_J.Environ.Sci.Health.B__1 Assessment of DNA damage and cholinesterase activity in soybean farmers in southern Brazil: High versus low pesticide exposure
Bertero_2019_Sci.Total.Environ_707_136129 Types of pesticides involved in domestic and wild animal poisoning in Italy
Chen_2019_Fish.Shellfish.Immunol_97_283 Subchronic effects of dietary selenium yeast and selenite on growth performance and the immune and antioxidant systems in Nile tilapia Oreochromis niloticus
Chokchaisiri_2019_Nat.Prod.Res__1 Morindaquinone, a new bianthraquinone from Morinda coreia roots
de Oliveira Dos Santos_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108683 Neurotoxic and respiratory effects of human use drugs on a Neotropical fish species, Phalloceros harpagos
Estrada-Valencia_2019_J.Enzyme.Inhib.Med.Chem_34_712 New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer s disease endowed with neurogenic properties
Fu_2019_Toxicology_430_152346 Tracing and attribution of V-type nerve agents in human exposure by strategy of assessing the phosphonylated and disulfide adducts on ceruloplasmin
Hallal_2019_Data.Brief_27_104775 Data on dysfunctional muscle contraction and genes contractile expression associated with chlorpyrifos exposure in slow twitch skeletal muscle
Hu_2019_Int.J.Neurosci__1 Tacrine modulates Kv2.1 channel gene expression and cell proliferation
Jaguezeski_2019_Vet.Microbiol__108528 Experimental listeriosis: A study of purinergic and cholinergic inflammatory pathway
Karumuri_2019_Toxicol.Rep_6_1295 Impact of chronic low dose exposure of monocrotophos in rat brain: Oxidative\/ nitrosative stress, neuronal changes and cholinesterase activity
Kienle_2019_PLoS.One_14_e0226278 Effects of treated wastewater on the ecotoxicity of small streams - Unravelling the contribution of chemicals causing effects
Kilic_2019_Bratisl.Lek.Listy_120_881 The effects and mechanisms of the action of galangin on spatial memory in rats
Kong_2019_Molecules_24_ Synergistic Inhibition of Acetylcholinesterase by Alkaloids Derived from Stephaniae Tetrandrae Radix, Coptidis Rhizoma and Phellodendri Chinensis Cortex
Leao_2019_J.Toxicol.Environ.Health.A__1 Toxicological evaluation of the herbicide Palace(R) in Drosophila melanogaster
Lee_2019_J.Neuroinflammation_16_267 Genetic deletion of soluble epoxide hydrolase delays the progression of Alzheimer's disease
Li_2019_Bioorg.Chem_95_103503 Protoilludane-type sesquiterpenoids from Armillaria sp. by co-culture with the endophytic fungus Epicoccumsp. associated with Gastrodia elata
Lisboa_2019_Molecules_25_ Toxicity and Antitumor Activity of a Thiophene-Acridine Hybrid
Liu_2019_PLoS.One_14_e0226698 Comparative transcriptome reveals the potential modulation mechanisms of estradiol affecting ovarian development of female Portunus trituberculatus
Lopes_2019_Parasit.Vectors_12_591 Insecticide resistance in Culex quinquefasciatus Say, 1823 in Brazil: a review
Macek Hrvat_2019_Toxicol.Lett_321_83 Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
Matejovsky_2019_ACS.Omega_4_20978 A Strip Biosensor with Guinea Green B and Fuchsin Basic Color Indicators on a Glass Nanofiber Carrier for the Cholinesterase Detection of Nerve Agents
Maxeiner_2019_Biol.Sex.Differ_10_62 Novel human sex-typing strategies based on the autism candidate gene NLGN4X and its male-specific gametologue NLGN4Y
Nagabooshanam_2019_Sci.Rep_9_19862 Electrochemical micro analytical device interfaced with portable potentiostat for rapid detection of chlorpyrifos using acetylcholinesterase conjugated metal organic framework using Internet of things
Nkuimi_2019_Plants.(Basel)_9_ Antioxidant and Enzyme Inhibitory Properties of the Polyphenolic-Rich Extract from an Ancient Apple Variety of Central Italy (Mela Rosa dei Monti Sibillini)
Park_2019_Medicine.(Baltimore)_98_e18406 Comparison of recovery profiles in patients with Parkinson's disease for 2 types of neuromuscular blockade reversal agent following deep brain stimulator implantation
Piccoli_2019_BMC.Pharmacol.Toxicol_20_83 Simultaneous exposure to vinylcyclohexene and methylmercury in Drosophila melanogaster: biochemical and molecular analyses
Pourshojaei_2019_Sci.Rep_9_19855 Phenoxyethyl Piperidine\/Morpholine Derivatives as PAS and CAS Inhibitors of Cholinesterases: Insights for Future Drug Design
Rodriguez_2019_Int.J.Mol.Sci_21_ Tetrahydroquinoline-Isoxazole\/Isoxazoline Hybrid Compounds as Potential Cholinesterases Inhibitors: Synthesis, Enzyme Inhibition Assays, and Molecular Modeling Studies
Shao_2019_Fitoterapia__104465 Colletotryptins A-F, new dimeric tryptophol derivatives from the endophytic fungus Colletotrichum sp. SC1355
Shin_2019_Alzheimers.Res.Ther_11_110 Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model
Silva_2019_Sci.Total.Environ_707_134434 Behavior and biochemical responses of the polychaeta Hediste diversicolor to polystyrene nanoplastics
Thamban_2019_Molecules_25_ Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Abeta Fibril Assembly
Tsagkaris_2019_Sensors.(Basel)_19_ A Hybrid Lab-on-a-Chip Injector System for Autonomous Carbofuran Screening
Umm_2019_J.Biol.Regul.Homeost.Agents_33_1797 Starring role of acetylcholinesterase from medicinal plants on lactate dehydrogenase production in cytotoxic hepatic cells
Wang_2019_Insects_11_ The Effect of Longwave Ultraviolet Light Radiation on Dendrolimus tabulaeformis Antioxidant and Detoxifying Enzymes
Xu_2019_Front.Cell.Neurosci_13_518 Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt\/mTOR Signaling
Yun_2019_Bioorg.Med.Chem.Lett__126900 Synthesis and biological evaluation of 4-arylcoumarins as potential anti-Alzheimer's disease agents
Jiang_2019_Saudi.J.Biol.Sci_26_2018 Clinical efficacy of intravenous infusion of atropine with micropump in combination with hemoperfusion on organophosphorus poisoning
Korany_2019_Biomolecules_10_ Comparative Structural Analysis of Different Mycobacteriophage-Derived Mycolylarabinogalactan Esterases (Lysin B)
Lemke_2019_ACS.Omega_4_22161 Chromenones as Multineurotargeting Inhibitors of Human Enzymes
Li_2019_Environ.Pollut_259_113868 Environmental co-exposure to TBT and Cd caused neurotoxicity and thyroid endocrine disruption in zebrafish, a three-generation study in a simulated environment
Stanciu_2019_Biomolecules_10_ Alzheimer's Disease Pharmacotherapy in Relation to Cholinergic System Involvement
Subramanian_2019_Adv.Exp.Med.Biol_1185_377 Role of the PNPLA2 Gene in the Regulation of Oxidative Stress Damage of RPE
Todirascu-Ciornea_2019_Evid.Based.Complement.Alternat.Med_2019_5256781 Schinus terebinthifolius Essential Oil Attenuates Scopolamine-Induced Memory Deficits via Cholinergic Modulation and Antioxidant Properties in a Zebrafish Model
Tripathi_2019_Bioorg.Chem_95_103506 Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease
Valek_2019_Int.J.Anal.Chem_2019_8538340 Indoxyl Acetate as a Substrate for Analysis of Lipase Activity
Woo_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_229_108698 Effects of trichlorfon on oxidative stress, neurotoxicity, and cortisol levels in common carp, Cyprinus carpio L., at different temperatures
Blacher_2019_Nature_572_474 Potential roles of gut microbiome and metabolites in modulating ALS in mice
Hu_2019_Cancers.(Basel)_11_ Synergy of Ginkgetin and Resveratrol in Suppressing VEGF-Induced Angiogenesis: A Therapy in Treating Colorectal Cancer
Hu_2019_J.Agric.Food.Chem_67_1127 Binding of Resveratrol to Vascular Endothelial Growth Factor Suppresses Angiogenesis by Inhibiting the Receptor Signaling
Hu_2019_FASEB.J_33_532 Polydatin suppresses VEGF-induced angiogenesis through binding with VEGF and inhibiting its receptor signaling
Ivasiv_2019_Curr.Top.Med.Chem_19_1694 Molecular Hybridization as a Tool for Designing Multitarget Drug Candidates for Complex Diseases
Lam_2019_Neurosci.Lett_707_134308 Asarones from Acori Tatarinowii Rhizoma stimulate expression and secretion of neurotrophic factors in cultured astrocytes
Wang_2019_J.Sep.Sci_42_2500 Simultaneous determination of short-chain fatty acids in human feces by HPLC with ultraviolet detection following chemical derivatization and solid-phase extraction segmental elution
Xu_2019_Front.Pharmacol_10_1130 Shexiang Baoxin Pill, a Formulated Chinese Herbal Mixture, Induces Neuronal Differentiation of PC12 Cells: A Signaling Triggered by Activation of Protein Kinase A
Tholken_2019_BMC.Genomics_20_88 Sequence and structural properties of circular RNAs in the brain of nurse and forager honeybees (Apis mellifera)
Aceves_2019_Eur.J.Neurosci_49_824 Selective remodeling of glutamatergic transmission to striatal cholinergic interneurons after dopamine depletion
Plotkin_2019_Neuroscientist_25_359 Thinking Outside the Box (and Arrow): Current Themes in Striatal Dysfunction in Movement Disorders
Rehani_2019_eNeuro_6_ Activity Patterns in the Neuropil of Striatal Cholinergic Interneurons in Freely Moving Mice Represent Their Collective Spiking Dynamics
Thakur_2019_Neurosci_412_248 alpha-Synuclein 2.0 - Moving towards Cell Type Specific Pathophysiology
Tiroshi_2019_PLoS.Comput.Biol_15_e1006782 Population dynamics and entrainment of basal ganglia pacemakers are shaped by their dendritic arbors
Aoyama_2019_Bioorg.Med.Chem.Lett__126888 Selective acetylcholinesterase inhibitors derived from muscle relaxant dantrolene
Fahmy_2019_Neurotoxicol_77_80 Neurotoxicity of green- synthesized magnetic iron oxide nanoparticles in different brain areas of wistar rats
Ghias_2019_Pak.J.Pharm.Sci_32_2325 Nootropic effects of synthetic flavonoid derivatives on scopolamine induced memory impairment in mice via cholinesterase inhibition and antioxidant system
Kou_2019_Bioorg.Med.Chem.Lett__126927 Design, synthesis and anti-Alzheimer's disease activity study of xanthone derivatives based on multi-target strategy
Schonkeren_2019_Neurogenetics_20_173 Nervous NDRGs: the N-myc downstream-regulated gene family in the central and peripheral nervous system
Yu_2019_Therap.Adv.Gastroenterol_12_1756284819858507 Characterization of the prognostic values of the NDRG family in gastric cancer
Aghoutane_2019_Bioelectrochemistry_132_107404 Development of a molecularly imprinted polymer electrochemical sensor and its application for sensitive detection and determination of malathion in olive fruits and oils
Blakely_2019_Neurochem.Int_123_1 The brain in flux: Genetic, physiologic, and therapeutic perspectives on transporters in the CNS
Carney_2019_Alzheimers.Dement.(N.Y)_5_732 Comparison of cholinesterase inhibitor safety in real-world practice
George_2019_Immunohematology_35_154 An update on the Cartwright (Yt) blood group system
Hou_2019_Ann.Transl.Med_7_634 Galanthamine improves myocardial ischemia-reperfusion-induced cardiac dysfunction, endoplasmic reticulum stress-related apoptosis, and myocardial fibrosis by suppressing AMPK\/Nrf2 pathway in rats
Huang_2019_Front.Microbiol_10_2846 New Dihydroisocoumarin Root Growth Inhibitors From the Sponge-Derived Fungus Aspergillus sp. NBUF87
Inberg_2019_Annu.Rev.Neurosci_42_365 Lessons from Worm Dendritic Patterning
Kim_2019_Nutrients_12_ Evaluating the Memory Enhancing Effects of Angelica gigas in Mouse Models of Mild Cognitive Impairments
Koshy_2019_Behav.Neurosci_133_448 Repetitive mild concussion in subjects with a vulnerable cholinergic system: Lasting cholinergic-attentional impairments in CHT+\/- mice
Panayotis_2019_Neuron_102_507 Hidden Figures: A Non-translated RNA Regulates Axonal Neurotrophin Signaling
Robinson_2019_PLoS.One_14_e0216417 Dopamine-dependent, swimming-induced paralysis arises as a consequence of loss of function mutations in the RUNX transcription factor RNT-1
Vilquin_2019_Front.Neurol_10_1343 The Muscle Is Not a Passive Target in Myasthenia Gravis
Das_2019_Cancer.Metastasis.Rev_38_455 Exosomes as a storehouse of tissue remodeling proteases and mediators of cancer progression
Kimberlin_2019_J.Mol.Biol_431_2869 SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped beta-Sandwich Fold Important for SOCE Modulation
Korkotian_2019_Oxid.Med.Cell.Longev_2019_7284967 Presenilin 1 Regulates [Ca(2+)]i and Mitochondria\/ER Interaction in Cultured Rat Hippocampal Neurons
Krishnaswamy_2019_Cell.Mol.Life.Sci_76_3229 Demystifying the extracellular matrix and its proteolytic remodeling in the brain: structural and functional insights
Lerner_2019_Cell.Rep_29_2144 ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus
Simchovitz_2019_FASEB.J_33_11223 NEAT1 is overexpressed in Parkinson's disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress
Bychkov_2019_PLoS.One_14_e0217339 Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of alpha7 nicotinic acetylcholine receptors
Elazar_2019_J.Cell.Biol_218_2887 Coordinated internodal and paranodal adhesion controls accurate myelination by oligodendrocytes
Garcia-Campos_2019_Cell_178_731 Deciphering the m(6)A Code via Antibody-Independent Quantitative Profiling
Horovitz_2019_Curr.Opin.Struct.Biol_58_10 Double-mutant cycles: new directions and applications
Karton-Lifshin_2019_Chem.Commun.(Camb)_55_12471 Effective neutralization of chemical warfare agents (HD, VX) by Me-DABCOF: a small molecule with dual action
Sapir_2019_Front.Cell.Neurosci_13_434 Building Bridges Between the Clinic and the Laboratory: A Meeting Review - Brain Malformations: A Roadmap for Future Research
Elazzaoui_2019_ScientificWorldJournal_2019_5875027 A Multibiomarker Approach to Assess the Health State of Coastal Ecosystem Receiving Desalination Plants in Agadir Bay, Morocco
Gharpure_2019_Neuron_104_501 Agonist Selectivity and Ion Permeation in the alpha3beta4 Ganglionic Nicotinic Receptor
Herrera_2019_Conf.Proc.IEEE.Eng.Med.Biol.Soc_2019_1159 A Biosensor for the Detection of Acetylcholine and Diazinon
Stokes_2019_J.Pharmacol.Exp.Ther_370_252 Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant beta Subunits Acquire Sensitivity to alpha7-Selective Positive Allosteric Modulators
Zhou_2019_Front.Mol.Neurosci_12_304 Molecular Architecture of Genetically-Tractable GABA Synapses in C. elegans
Del Angel_2019_Hum.Mutat_40_2007 Large-scale functional LIPA variant characterization to improve birth prevalence estimates of lysosomal acid lipase deficiency
Evans_2019_Arterioscler.Thromb.Vasc.Biol_39_2480 Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease
Ghajarbeygi_2019_J.Pharmacopuncture_22_231 An In Vitro and In Vivo Cholinesterase Inhibitory Activity of Pistacia khinjuk and Allium sativum Essential Oils
Gomaraschi_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_158523 Lipid accumulation impairs lysosomal acid lipase activity in hepatocytes: Evidence in NAFLD patients and cell cultures
Guo_2019_Oxid.Med.Cell.Longev_2019_1707218 Study on the Multitarget Synergistic Effects of Kai-Xin-San against Alzheimer's Disease Based on Systems Biology
Johnson_2019_Aging.Cell_18_e13048 The role of lipid metabolism in aging, lifespan regulation, and age-related disease
Kandhi_2019_Pulm.Circ_9_2045894019895947 Reciprocal actions of constrictor prostanoids and superoxide in chronic hypoxia-induced pulmonary hypertension: roles of EETs
Khuat_2019_Genes.(Basel)_10_ Characterization of Solanum melongena Thioesterases Related to Tomato Methylketone Synthase 2
Li_2019_J.Agric.Food.Chem_67_14066 Inhibitory Effect of Condensed Tannins from Banana Pulp on Cholesterol Esterase and Mechanisms of Interaction
Jin_2019_J.Nutr.Sci_8_e38 Dietary choline supplementation attenuated high-fat diet-induced inflammation through regulation of lipid metabolism and suppression of NFkappaB activation in juvenile black seabream (Acanthopagrus schlegelii)
Li_2019_Anal.Methods_11_5203 A disposable acetylcholine esterase sensor for As(III) determination in groundwater matrix based on 4-acetoxyphenol hydrolysis
Ma_2019_Front.Neurosci_13_1400 Neuroprotective Effect of Resveratrol via Activation of Sirt1 Signaling in a Rat Model of Combined Diabetes and Alzheimer's Disease
Malik_2019_Cureus_11_e6451 Correlation Between Donepezil and QTc Prolongation and Torsades de Pointes: A Very Rare Phenomenon
Matsuo_2019_JA.Clin.Rep_5_39 Low serum cholinesterase predicts complication risk after orthopedic surgery in elderly patients: an observational pilot study
Sun_2019_Front.Bioeng.Biotechnol_7_486 Optimization of the Lipase-Catalyzed Selective Amidation of Phenylglycinol
Domingues_2019_Front.Mol.Neurosci_12_325 Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism
Magaletta_2019_FASEB.Bioadv_1_450 The Kinesin-3 motor, KLP-4, mediates axonal organization and cholinergic signaling in Caenorhabditis elegans
Sarikurkcu_2019_Front.Pharmacol_10_1642 Phenolic Profile and Bioactivities of Sideritis perfoliata L.: The Plant, Its Most Active Extract, and Its Broad Biological Properties
Kolosova_2019_Dokl.Biol.Sci_489_165 Set of Enzymatic Bioassays for Assessment of Soil Contamination
Eskiocak_2019_Lipids.Health.Dis_18_232 A novel mutation of ABHD5 gene in a Chanarin Dorfman patient with unusual dermatological findings
Jiang_2019_Bioresour.Technol_294_122231 Integration of lipidomic and transcriptomic profiles reveals novel genes and regulatory mechanisms of Schizochytrium sp. in response to salt stress
Kalyon_2019_Turk.J.Gastroenterol_30_105 Chanarin-Dorfman syndrome
Kim_2019_Proc.Natl.Acad.Sci.U.S.A_116_9877 Cell contact and Nf2\/Merlin-dependent regulation of TEAD palmitoylation and activity
Li_2019_Gene_704_113 A novel ABHD12 nonsense variant in Usher syndrome type 3 family with genotype-phenotype spectrum review
Louhichi_2019_Orphanet.J.Rare.Dis_14_112 Thyroid involvement in Chanarin-Dorfman syndrome in adults in the largest series of patients carrying the same founder mutation in ABHD5 gene
Miklosz_2019_Int.J.Mol.Sci_20_ Assessment of the Main Compounds of the Lipolytic System in Treadmill Running Rats: Different Response Patterns between the Right and Left Ventricle
Raza_2019_Genes.(Basel)_10_ Advances of Molecular Markers and Their Application for Body Variables and Carcass Traits in Qinchuan Cattle
Voss_2019_Diabetologia_62_494 Substrate metabolism, hormone and cytokine levels and adipose tissue signalling in individuals with type 1 diabetes after insulin withdrawal and subsequent insulin therapy to model the initiating steps of ketoacidosis
Yook_2019_Proc.Natl.Acad.Sci.U.S.A_116_10988 Leptin in hippocampus mediates benefits of mild exercise by an antioxidant on neurogenesis and memory
Youssefian_2019_J.Hepatol_71_366 Inherited non-alcoholic fatty liver disease and dyslipidemia due to monoallelic ABHD5 mutations
Kronlage_2019_Circulation_140_580 O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart From Failure
Abdel-Rasoul_2019_Egypt.J.Occup.Med_43_331 Neurobehavioral and Menstrual Disorders among Adolescent Females Environmentally Exposed to Pesticides, Menoufia Governorate, Egypt
Algaissi_2019_J.Infect.Dis_219_829 Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease
Blaikie_2019_Medchemcomm_10_2052 Current and emerging therapeutic targets of alzheimer's disease for the design of multi-target directed ligands
Dawson_2019_Vector.Borne.Zoonotic.Dis_19_174 What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review
Hashem_2019_J.Infect.Dis_220_1558 A Highly Immunogenic, Protective, and Safe Adenovirus-Based Vaccine Expressing Middle East Respiratory Syndrome Coronavirus S1-CD40L Fusion Protein in a Transgenic Human Dipeptidyl Peptidase 4 Mouse Model
Iwata-Yoshikawa_2019_J.Virol_93_ Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus
Jia_2019_Emerg.Microbes.Infect_8_760 Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection
Jiang_2019_Viruses_11_ Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV
Kim_2019_PLoS.One_14_e0220196 Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirus
Kim_2019_Emerg.Infect.Dis_25_1161 Sequential Emergence and Wide Spread of Neutralization Escape Middle East Respiratory Syndrome Coronavirus Mutants, South Korea, 2015
Kleine-Weber_2019_J.Virol_93_ Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization
Mubarak_2019_J.Immunol.Res_2019_6491738 Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Infection, Immunological Response, and Vaccine Development
Park_2019_Nat.Struct.Mol.Biol_26_1151 Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors
Renda_2019_Iran.J.Pharm.Res_18_1831 The Volatile Chemical Compositions of the Essential Oil\/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey
Te_2019_Transbound.Emerg.Dis_66_831 Co-localization of Middle East respiratory syndrome coronavirus (MERS-CoV) and dipeptidyl peptidase-4 in the respiratory tract and lymphoid tissues of pigs and llamas
Widagdo_2019_J.Virol_93_ Species-Specific Colocalization of Middle East Respiratory Syndrome Coronavirus Attachment and Entry Receptors
Mahdavinia_2019_Int.J.Mol.Cell.Med_8_141 Protective Effect of Naringin on Bisphenol A-Induced Cognitive Dysfunction and Oxidative Damage in Rats
Nagaraju_2019_Interdiscip.Toxicol_12_129 Plasma paraoxonase1 activity in rats treated with monocrotophos: a study of the effect of duration of exposure
Nwobi_2019_Interdiscip.Toxicol_12_136 Positive and inverse correlation of blood lead level with erythrocyte acetylcholinesterase and intelligence quotient in children: implications for neurotoxicity
Xie_2019_Reprod.Toxicol_83_1 Effects of two environmental endocrine disruptors di-n-butyl phthalate (DBP) and mono-n-butyl phthalate (MBP) on human sperm functions in vitro
Chaudhary_2019_Development_146_ Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wing
Han_2019_J.Mater.Chem.B_7_2613 Peroxidase-like activity of acetylcholine-based colorimetric detection of acetylcholinesterase activity and an organophosphorus inhibitor
Mattiazzi_2019_Rev.Bras.Med.Trab_17_239 Hearing screening and cholinesterase activity among rural workers exposed to pesticides
Sundberg_2019_Dev.Cell_51_387 Syndecan-1 Mediates Sorting of Soluble Lipoprotein Lipase with Sphingomyelin-Rich Membrane in the Golgi Apparatus
Nikookar_2019_J.Arthropod.Borne.Dis_13_378 First Report of Biochemical Mechanisms of Insecticide Resistance in the Field Population of Culex pipiens (Diptera: Culicidae) from Sari, Mazandaran, North of Iran
Lai_2019_Int.J.Geriatr.Psychiatry_34_1287 Prevalence of delusions in drug-naive Alzheimer disease patients: A meta-analysis
Shirayama_2019_Brain.Imaging.Behav_13_75 rCBF and cognitive impairment changes assessed by SPECT and ADAS-cog in late-onset Alzheimer's disease after 18 months of treatment with the cholinesterase inhibitors donepezil or galantamine
Ajiboye_2019_J.Basic.Clin.Physiol.Pharmacol_31_ In vitro antioxidant and enzyme inhibitory properties of the n-butanol fraction of Senna podocarpa (Guill. and Perr.) leaf
Ammar_2019_J.Assist.Reprod.Genet_36_2367 Novel association between apoptotic sperm biomarkers with seminal biochemical parameters and acetylcholinesterase activity in patients with teratozoospermia
Anadozie_2019_J.Basic.Clin.Physiol.Pharmacol_30_ Prevention of short-term memory impairment by Bryophyllum pinnatum (Lam.) Oken and its effect on acetylcholinesterase changes in CCl4-induced neurotoxicity in rats
Aras_2019_Chem.Biodivers_16_e1900341 Phytochemical Content, Antidiabetic, Anticholinergic, and Antioxidant Activities of Endemic Lecokia cretica Extracts
Asadi_2019_Chem.Biodivers_16_e1900370 Design, Synthesis, Molecular Docking, and Cholinesterase Inhibitory Potential of Phthalimide-Dithiocarbamate Hybrids as New Agents for Treatment of Alzheimer's Disease
Baluchnejadmojarad_2019_Metab.Brain.Dis_34_1747 Safranal, an active ingredient of saffron, attenuates cognitive deficits in amyloid beta-induced rat model of Alzheimer's disease: underlying mechanisms
Banaee_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_220_62 Sub-lethal effects of dimethoate alone and in combination with cadmium on biochemical parameters in freshwater snail, Galba truncatula
Baratta_2019_Liver.Int_39_2301 Lysosomal acid lipase activity and liver fibrosis in the clinical continuum of non-alcoholic fatty liver disease
Batista_2019_Cardiovasc.Toxicol_19_548 Intermittent Exposure to Chlorpyrifos Differentially Impacts Neuroreflex Control of Cardiorespiratory Function in Rats
Bayrak_2019_Turk.J.Urol_45_401 Underactive bladder: A review of the current treatment concepts
Blanco-Silvente_2019_Eur.J.Clin.Pharmacol_75_1659 Study of the strength of the evidence and the redundancy of the research on pharmacological treatment for Alzheimer's disease: a cumulative meta-analysis and trial sequential analysis
Chandar_2019_Chem.Biol.Interact_13ChEPon_310_108715 Molecular dynamics simulations of the interaction of Mouse and Torpedo acetylcholinesterase with covalent inhibitors explain their differential reactivity: Implications for drug design
Chen_2019_J.Med.Food_22_1009 Effects of Bread Yeast Cell Wall Beta-Glucans on Mice with Loperamide-Induced Constipation
Chi_2019_J.Vis.Exp__ Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Choueiry_2019_Int.J.Psychophysiol_145_70 Combining CDP-choline and galantamine, an optimized alpha7 nicotinic strategy, to ameliorate sensory gating to speech stimuli in schizophrenia
Cristobal-Mondragon_2019_FEBS.J_286_4797 FRET-based analysis and molecular modeling of the human GPN-loop GTPases 1 and 3 heterodimer unveils a dominant-negative protein complex
Cui_2019_Acta.Pharmacol.Sin_40_1386 Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination
Dai_2019_J.Nat.Prod_82_2627 Cholinesterase Inhibitory Arisugacins L-Q from a Penicillium sp. Isolate Obtained through a Citizen Science Initiative and Their Activities in a Phenotype-Based Zebrafish Assay
Dayan_2019_J.Phys.Chem.A_123_9456 In Situ Detoxification of Venomous Agent X Surrogate Profenofos by Doped Titanium Dioxide Nanoparticles under Illumination at the UV and Visible Ranges
de Medeiros_2019_Mol.Neurobiol_56_7355 Cholinergic Differentiation of Human Neuroblastoma SH-SY5Y Cell Line and Its Potential Use as an In vitro Model for Alzheimer's Disease Studies
Despotovic_2019_Protein.Eng.Des.Sel_32_169 A mixture of three engineered phosphotriesterases enables rapid detoxification of the entire spectrum of known threat nerve agents
Dong_2019_J.Biosci.Bioeng_128_525 Improving the acetylcholinesterase inhibitory effect of Illigera aromatica by fermentation with Clonostachys rogersoniana
Dorling_2019_Am.J.Clin.Nutr_110_1055 A randomized crossover trial assessing the effects of acute exercise on appetite, circulating ghrelin concentrations, and butyrylcholinesterase activity in normal-weight males with variants of the obesity-linked FTO rs9939609 polymorphism
Ekwutosi_2019_Drug.Res.(Stuttg)_69_551 Evaluation of the Memory Enhancing Activity of Dichloromethane Fraction of the Methanolic Extract of Pycnanthus angolensis Stem Bark on Experimental Models of Memory Impairment
Eshetie_2019_Pharmacotherapy_39_1146 Medication Use for Comorbidities in People with Alzheimer's Disease: An Australian Population-Based Study
Fayez_2019_Fundam.Clin.Pharmacol_33_634 Neuroprotective effects of zafirlukast, piracetam and their combination on L-Methionine-induced vascular dementia in rats
Fritsch_2019_Antioxid.Redox.Signal_31_1235 The MarR-Type Repressor MhqR Confers Quinone and Antimicrobial Resistance in Staphylococcus aureus
Galarce-Bustos_2019_Phytochem.Anal_30_679 Detection and identification of acetylcholinesterase inhibitors in Annona cherimola Mill. by effect-directed analysis using thin-layer chromatography-bioassay-mass spectrometry
Gao_2019_Pest.Manag.Sci_75_3167 Laboratory and field evaluation of the aphidicidal activity of moso bamboo (Phyllostachys pubescens) leaf extract and identification of the active components
Geiger_2019_Environ.Microbiol_21_3601 Enzymes involved in phthalate degradation in sulphate-reducing bacteria
Ghribi_2019_Environ.Sci.Pollut.Res.Int_26_29704 Testing the impact of contaminated sediments from the southeast marine coast of Tunisia on biota: a multibiomarker approach using the flatfish Solea senegalensis
Gorecki_2019_Future.Med.Chem_11_2625 Tacroximes: novel unique compounds for the recovery of organophosphorus-inhibited acetylcholinesterase
Gothwal_2019_Bioconjug.Chem_30_2573 Lactoferrin Coupled Lower Generation PAMAM Dendrimers for Brain Targeted Delivery of Memantine in Aluminum-Chloride-Induced Alzheimer's Disease in Mice
Grandis_2019_Ann.Bot_124_1067 Cell wall hydrolases act in concert during aerenchyma development in sugarcane roots
Guo_2019_J.Nat.Prod_82_3288 Glucoconjugated Monoterpene Indole Alkaloids from Uncaria rhynchophylla
Guo_2019_Food.Funct_10_6915 Chemical characterization of the main bioactive polyphenols from the roots of Morus australis (mulberry)
Hart_2019_Genetics_213_1415 Stress-Induced Neuron Remodeling Reveals Differential Interplay Between Neurexin and Environmental Factors in Caenorhabditis elegans
He_2019_Dig.Dis.Sci_64_3182 Vitamin E Ameliorates Lipid Metabolism in Mice with Nonalcoholic Fatty Liver Disease via Nrf2\/CES1 Signaling Pathway
Hettiarachchi_2019_J.Control.Release_314_125 Nanoparticle-mediated approaches for Alzheimer's disease pathogenesis, diagnosis, and therapeutics
Hobbs_2019_Am.J.Respir.Crit.Care.Med_200_1402 Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis
Honarpisheh_2019_Br.J.Pharmacol_176_4173 Sex as a biological variable in the pathology and pharmacology of neurodegenerative and neurovascular diseases
Hong_2019_J.Nat.Prod_82_3221 Alkaloids from the Branches and Leaves of Elaeocarpus angustifolius
Hu_2019_J.Clin.Invest_129_5204 Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity
Hu_2019_Anal.Bioanal.Chem_411_7879 Leek-derived codoped carbon dots as efficient fluorescent probes for dichlorvos sensitive detection and cell multicolor imaging
Huang_2019_J.Agric.Food.Chem_67_11244 One-Step Facile Synthesis of Nitrogen-Doped Carbon Dots: A Ratiometric Fluorescent Probe for Evaluation of Acetylcholinesterase Activity and Detection of Organophosphorus Pesticides in Tap Water and Food
Imamura_2019_J.Neurochem__e14927 Donepezil-induced oligodendrocyte differentiation is mediated through estrogen receptors
Jee_2019_J.Am.Chem.Soc_141_20062 Enhanced Diffusion and Oligomeric Enzyme Dissociation
Jeschke_2019_Exp.Clin.Transplant_17_665 Single-Center Retrospective Study of Clinical and Laboratory Features That Predict Survival of Patients With Budd-Chiari Syndrome After Liver Transplant
Jia_2019_J.Alzheimers.Dis_72_1313 Sixteen-Week Interventional Study to Evaluate the Clinical Effects and Safety of Rivastigmine Capsules in Chinese Patients with Alzheimer's Disease
Jiang_2019_Chem.Commun.(Camb)_55_11358 Ratiometric two-photon fluorescent probe for in situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication
Joncas_2019_Prostate_79_1767 Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients
Kabir_2019_Curr.Pharm.Des_25_3519 Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning
Karahisar_2019_Chem.Biodivers_16_e1900333 Metabolite Profiling by Hyphenated Liquid Chromatographic Mass Spectrometric Technique (HPLC-DAD-ESI-Q-TOF-MS\/MS) and Neurobiological Potential of Haplophyllum sahinii and H. vulcanicum Extracts
Kiss-Szeman_2019_Curr.Protein.Pept.Sci_20_1089 Achieving Functionality Through Modular Build-up: Structure and Size Selection of Serine Oligopeptidases
Klichkhanov_2019_Bull.Exp.Biol.Med_168_229 A New Tellurium- and Selenoorganic Compound as an Inhibitor of Acetylcholinesterase in Brain
Knez_2019_Curr.Alzheimer.Res_16_801 Biological Evaluation of 8-Hydroxyquinolines as Multi-Target Directed Ligands for Treating Alzheimer's Disease
Ko_2019_Planta.Med_85_1363 Lespedeza bicolor Extract Improves Amyloid Beta25 - 35-Induced Memory Impairments by Upregulating BDNF and Activating Akt, ERK, and CREB Signaling in Mice
Kuljis_2019_eNeuro_6_ Fluorescence-Based Quantitative Synapse Analysis for Cell Type-Specific Connectomics
Kuo_2019_Mol.Neurobiol_56_8451 Soluble Epoxide Hydrolase Inhibition Attenuates Excitotoxicity Involving 14,15-Epoxyeicosatrienoic Acid-Mediated Astrocytic Survival and Plasticity to Preserve Glutamate Homeostasis
Lambrianides_2019_Neuromuscul.Disord_29_771 A novel case of inclusion body myositis and myasthenia gravis
Lee_2019_Biomater.Sci_7_4624 Esterase-sensitive cleavable histone deacetylase inhibitor-coupled hyaluronic acid nanoparticles for boosting anticancer activities against lung adenocarcinoma
Levan_2019_Nat.Microbiol_4_1851 Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance
Li_2019_Soft.Matter_15_8197 Multi-charged bis(p-calixarene)\/pillararene functionalized gold nanoparticles for ultra-sensitive sensing of butyrylcholinesterase
Li_2019_Bioanalysis_11_2145 Fluoride reactivation-enabled sensitive quantification of tabun adducts on human serum albumin by GC-MS\/MS via isotope dilution
Linna_2019_J.Alzheimers.Dis_71_1297 Impact of Anti-Dementia Medication on the Risk of Death and Causes of Death in Alzheimer's Disease
Liu_2019_J.Anim.Physiol.Anim.Nutr.(Berl)_103_1934 Dietary mulberry leaf powder affects growth performance, carcass traits and meat quality in finishing pigs
Lorke_2019_J.Appl.Toxicol_39_1506 Oximes as pretreatment before acute exposure to paraoxon
Malek_2019_J.Med.Chem_62_11416 New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition
Malek_2019_Curr.Alzheimer.Res_16_815 Synthesis and Biological Evaluation of Novel Chromone+Donepezil Hybrids for Alzheimer's Disease Therapy
Malekshah_2019_J.Control.Release_311-312_273 Bioengineered adipose-derived stem cells for targeted enzyme-prodrug therapy of ovarian cancer intraperitoneal metastasis
Margus_2019_J.Econ.Entomol_112_2316 Can Indirect Herbicide Exposure Modify the Response of the Colorado Potato Beetle to an Organophosphate Insecticide?
Mathew_2019_CNS.Neurol.Disord.Drug.Targets_18_432 Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review
McCabe_2019_Age.Ageing_48_711 Patient and companion shared decision making and satisfaction with decisions about starting cholinesterase medication at dementia diagnosis
Meric_2019_J.Clin.Periodontol_46_1155 Cholinergic signalling mechanisms and early implant healing phases in healthy versus generalized aggressive periodontitis patients: A prospective, case-control study
Mezeiova_2019_Curr.Alzheimer.Res_16_772 Donepezil Derivatives Targeting Amyloid-beta Cascade in Alzheimer's Disease
Mishra_2019_J.Comput.Biol_26_1470 Identification of a Novel Scaffold for Inhibition of Dipeptidyl Peptidase-4
Moeini_2019_Planta.Med_85_1326 Pistacia Genus as a Potential Source of Neuroprotective Natural Products
Moj_2019_Clin.Pharmacokinet_58_1577 A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Model of Dabigatran Etexilate, Dabigatran and Dabigatran Glucuronide in Healthy Adults and Renally Impaired Patients
Morsy_2019_J.Alzheimers.Dis_72_S145 Current and Emerging Pharmacological Targets for the Treatment of Alzheimer's Disease
Moss_2019_J.Alzheimers.Dis_71_1099 Is Combining an Anticholinergic with a Cholinesterase Inhibitor a Good Strategy for High-Level CNS Cholinesterase Inhibition?
Mukhametgalieva_2019_Chem.Biol.Interact_310_108702 Time-course of human cholinesterases-catalyzed competing substrate kinetics
Nagao_2019_J.Clin.Lipidol_13_839 Serum concentration of full-length- and carboxy-terminal fragments of endothelial lipase predicts future cardiovascular risks in patients with coronary artery disease
Nakada_2019_Thorac.Cancer_10_1945 Risk factors and cancer recurrence associated with postoperative complications after thoracoscopic lobectomy for clinical stage I non-small cell lung cancer
Nan_2019_Mol.Biotechnol_61_892 A Novel VIII Carboxylesterase with High Hydrolytic Activity Against Ampicillin from a Soil Metagenomic Library
Naz_2019_Protein.Pept.Lett_26_919 Exploration of Fungal Lipase as Direct Target of Eugenol through Spectroscopic Techniques
Nogueira_2019_Environ.Toxicol_34_1177 Embryonic development, locomotor behavior, biochemical, and epigenetic effects of the pharmaceutical drugs paracetamol and ciprofloxacin in larvae and embryos of Danio rerio when exposed to environmental realistic levels of both drugs
Olasehinde_2019_Metab.Brain.Dis_34_1615 Neuroprotective effects of some seaweeds against Zn - induced neuronal damage in HT-22 cells via modulation of redox imbalance, inhibition of apoptosis and acetylcholinesterase activity
Omoarelojie_2019_Ann.Bot_124_749 Strigolactones and their crosstalk with other phytohormones
Omole_2019_Environ.Toxicol_34_1303 Barium chloride dose-dependently induced heart and lung injury in Wistar rats
Ooi_2019_Oral.Maxillofac.Surg_23_481 Factors related to patients' nutritional state after orthognathic surgery
Oskoe_2019_J.Biomed.Mater.Res.B.Appl.Biomater_107_2178 The effect of esterase enzyme on aging dental composites
Pala_2019_Environ.Sci.Pollut.Res.Int_26_36869 The effect of a glyphosate-based herbicide on acetylcholinesterase (AChE) activity, oxidative stress, and antioxidant status in freshwater amphipod: Gammarus pulex (Crustacean)
Pan_2019_ACS.Chem.Neurosci_10_4741 Fascaplysin Derivatives Are Potent Multitarget Agents against Alzheimer's Disease: in Vitro and in Vivo Evidence
Panza_2019_Brain_142_2905 Time to test antibacterial therapy in Alzheimer's disease
Pourshojaei_2019_Mini.Rev.Med.Chem_19_1577 Highly Significant Scaffolds to Design and Synthesis Cholinesterase Inhibitors as Anti-Alzheimer Agents
Proskocil_2019_Am.J.Respir.Cell.Mol.Biol_61_620 Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells
Ram_2019_Curr.Alzheimer.Res_16_1230 Dual Inhibition of DPP-4 and Cholinesterase Enzymes by the Phytoconstituents of the Ethanolic Extract of Prosopis cineraria Pods: Therapeutic Implications for the Treatment of Diabetes-associated Neurological Impairments
Rawlings_2019_Biochimie_166_4 Origins of peptidases
Reeta_2019_CNS.Neurol.Disord.Drug.Targets_18_643 Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease
Restrepo_2019_J.Neurosci_39_9065 Modeling a Neurexin-3alpha Human Mutation in Mouse Neurons Identifies a Novel Role in the Regulation of Transsynaptic Signaling and Neurotransmitter Release at Excitatory Synapses
Riquelme_2019_J.Endocrinol_242_115 Role of ovarian sympathetic nerves and cholinergic local system during cold stress
Rodrigues_2019_J.Cardiovasc.Pharmacol_74_542 Intrinsic Adaptation of SHR Right Atrium Reduces Heart Rate
Scheiner_2019_J.Med.Chem_62_9078 Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo
Schelter_2019_J.Alzheimers.Dis_72_931 Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer's Disease
Setya_2019_Curr.Drug.Deliv_16_902 Design and Development of Novel Transdermal Nanoemulgel for Alzheimer's Disease: Pharmacokinetic, Pharmacodynamic and Biochemical Investigations
Sharifkhodaei_2019_Development_146_ Scribble and Discs Large mediate tricellular junction formation
Sharma_2019_ACS.Chem.Neurosci_10_4361 Novel Molecular Hybrids of N-Benzylpiperidine and 1,3,4-Oxadiazole as Multitargeted Therapeutics to Treat Alzheimer's Disease
Shuai_2019_Future.Med.Chem_11_2687 Design, synthesis and molecular modeling of isothiochromanone derivatives as acetylcholinesterase inhibitors
Simunkova_2019_Arch.Toxicol_93_2491 Management of oxidative stress and other pathologies in Alzheimer's disease
Snowden_2019_J.Alzheimers.Dis_72_35 Neurotransmitter Imbalance in the Brain and Alzheimer's Disease Pathology
Srivastava_2019_J.Biol.Chem_294_17875 Large-scale conformational rearrangement of the alpha5-helix of Galpha subunits in complex with the guanine nucleotide exchange factor Ric8A
Takeuchi_2019_Intern.Med_58_3057 Decrease in Butyrylcholinesterase Accompanied by Intermediate-like Syndrome after Massive Ingestion of a Glyphosate-surfactant
Tepmongkol_2019_Brain.Imaging.Behav_13_1665 Early prediction of donepezil cognitive response in Alzheimer's disease by brain perfusion single photon emission tomography
Torrente_2019_Vet.Clin.Pathol_48_740 The diagnostic and prognostic value of paraoxonase-1 and butyrylcholinesterase activities compared with acute-phase proteins in septic dogs and stratified by the acute patient physiologic and laboratory evaluation score
Torres_2019_J.Nat.Prod_82_2489 Labdanes, Withanolides, and Other Constituents from Physalis nicandroides
Unterbuchner_2019_Anaesthesist_68_744 [Algorithm-based preventive strategies for avoidance of residual neuromuscular blocks]
Vallianatou_2019_Neuropsychopharmacology_44_2091 Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition
Volk_2019_Planta_250_2083 Two novel methylesterases from Olea europaea contribute to the catabolism of oleoside-type secoiridoid esters
Wang_2019_Anal.Chem_91_13831 Electropolymerization-Induced Positively Charged Phenothiazine Polymer Photoelectrode for Highly Sensitive Photoelectrochemical Biosensing
Wessler_2019_Int.J.Dev.Neurosci_78_222 Acute exposure to leucine modifies behavioral parameters and cholinergic activity in zebrafish
Wojtunik-Kulesza_2019_Chem.Biodivers_16_e1900434 Natural Monoterpenes: Much More than Only a Scent
Wu_2019_J.Viral.Hepat_26_1334 HEV-LFS : A novel scoring model for patients with hepatitis E virus-related liver failure
Wu_2019_J.Agric.Food.Chem_67_11877 Induction of Antiphytopathogenic Metabolite and Squalene Production and Phytotoxin Elimination by Adjustment of the Mode of Fermentation in Cocultures of Phytopathogenic Nigrospora oryzae and Irpex lacteus
Yang_2019_Anal.Chem_91_12874 A Simple 3D-Printed Enzyme Reactor Paper Spray Mass Spectrometry Platform for Detecting BuChE Activity in Human Serum
Yi_2019_J.Med.Food_22_1208 Lactobacillus plantarum CQPC02-Fermented Soybean Milk Improves Loperamide-Induced Constipation in Mice
Yin_2019_Behav.Pharmacol_30_730 Sevoflurane-induced inflammation development: involvement of cholinergic anti-inflammatory pathway
Yoo_2019_Chem.Commun.(Camb)_55_14574 A fluorescent probe for butyrylcholinesterase activity in human serum based on a fluorophore with specific binding affinity for human serum albumin
Yoo_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_1438 A novel enantioselective SGNH family esterase (NmSGNH1) from Neisseria meningitides: Characterization, mutational analysis, and ester synthesis
Yu_2019_Int.Clin.Psychopharmacol_34_312 Trends of antidementia drugs use in outpatients with Alzheimer's disease in six major cities of China: 2012-2017
Yu_2019_Drug.Metab.Pharmacokinet_34_308 Carboxylesterase catalyzed (18)O-labeling of carboxylic acid and its potential application in LC-MS\/MS based quantification of drug metabolites
Yuan_2019_Environ.Sci.Technol_53_14638 Bisphenol F-Induced Neurotoxicity toward Zebrafish Embryos
Zhang_2019_J.Med.Chem_62_8532 Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity
Zhang_2019_ACS.Appl.Mater.Interfaces_11_47311 Bio-\/Nanoimmobilization Platform Based on Bioinspired Fibrin-Bone@Polydopamine-Shell Adhesive Composites for Biosensing
Zhang_2019_Food.Funct_10_7315 Hydroxy-alpha-sanshool isolated from Zanthoxylum bungeanum attenuates learning and memory impairments in scopolamine-treated mice
Zhang_2019_Anal.Chem_91_15866 Gold Nanoclusters\/Iron Oxyhydroxide Platform for Ultrasensitive Detection of Butyrylcholinesterase
Cayan_2019_Int.J.Med.Mushrooms_21_1075 Chemical Profile, In Vitro Enzyme Inhibitory, and Antioxidant Properties of Stereum Species (Agaricomycetes) from Turkey
Ergul_2019_Turk.J.Pharm.Sci_16_401 In Vitro Evaluation of the Chemical Composition and Various Biological Activities of Ficus carica Leaf Extracts
Asano_2019_J.Dermatol_46_e19 Identification of a novel splice site mutation in the LIPH gene in a Japanese family with autosomal recessive woolly hair
Kubicki_2019_Mar.Drugs_17_ Marine Biosurfactants: Biosynthesis, Structural Diversity and Biotechnological Applications
Paulsen_2019_Philos.Trans.R.Soc.Lond.B.Biol.Sci_374_20190279 Comparative studies of endocannabinoid modulation of pain
Zhai_2019_J.Ind.Microbiol.Biotechnol_46_887 Effects of codon optimization and glycosylation on the high-level production of hydroxynitrile lyase from Chamberlinius hualienensis in Pichia pastoris
Crivellente_2019_EFSA.J_17_e05800 Establishment of cumulative assessment groups of pesticides for their effects on the nervous system
Dujardin_2019_EFSA.J_17_e05764 Cumulative dietary exposure assessment of pesticides that have acute effects on the nervous system using SAS((R)) software
Amara_2019_Cell.Chem.Biol_26_35 Synthetic Fluorogenic Peptides Reveal Dynamic Substrate Specificity of Depalmitoylases
Chen_2019_Biol.Chem_401_165 Synthetic and biological approaches to map substrate specificities of proteases
Lopes_2019_Medchemcomm_10_2089 Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling
Kramer_2019_J.Med.Chem_62_8443 Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain
Carnovale_2019_Expert.Opin.Drug.Saf_18_1099 Bullous pemphigoid induced by dipeptidyl peptidase-4 (DPP-4) inhibitors: a pharmacovigilance-pharmacodynamic\/pharmacokinetic assessment through an analysis of the vigibase
Lin_2019_J.Acute.Med_9_189 Successful Resuscitation of a Young Girl Who Drank Rivastigmine With Respiratory Failure
Basri_2019_J.Oleo.Sci_68_329 Lipase-catalyzed Production and Purification of Palm Esters Using Stirred Tank Reactors (STR)
Brys_2019_Int.J.Anal.Chem_2019_5417962 The Synthesis Followed by Spectral and Calorimetric Evaluation of Stability of Human Milk Fat Substitutes Obtained from Thistle Milk and Lard
Calinescu_2019_Ultrason.Sonochem_54_32 A reactor designed for the ultrasonic stimulation of enzymatic esterification
Chen_2019_J.Oleo.Sci_68_1125 Highly Selective Synthesis of Monolaurin via Enzymatic Transesterification under Batch and Continuous Flow Conditions
Du_2019_Org.Biomol.Chem_17_807 The convenient Michael addition of imidazoles to acrylates catalyzed by Lipozyme TL IM from Thermomyces lanuginosus in a continuous flow microreactor
Encinar_2019_Bioprocess.Biosyst.Eng_42_157 Sunflower oil transesterification with methanol using immobilized lipase enzymes
Kim_2019_Food.Chem_270_332 Production of stearidonic acid-rich triacylglycerol via a two-step enzymatic esterification
Lee_2019_Biomacromolecules_20_705 Lipase-Catalyzed Regioselective Synthesis of Dextrin Esters
Ma_2019_J.Food.Sci.Technol_56_835 Synthesis of cocoa butter substitutes from Cinnamomum camphora seed oil and fully hydrogenated palm oil by enzymatic interesterification
Pang_2019_J.Oleo.Sci_68_131 Physicochemical Properties, Crystallization Behavior and Oxidative Stabilities of Enzymatic Interesterified Fats of Beef Tallow, Palm Stearin and Camellia Oil Blends
Suhendra_2019_Molecules_24_ Synthesis and Characterization of N-Methyl Fatty Hydroxamic Acids from Ketapang Seed Oil Catalyzed by Lipase
Wang_2019_Food.Sci.Nutr_7_2361 Ultrasonic-pretreated lipase-catalyzed synthesis of medium-long-medium lipids using different fatty acids as sn-2 acyl-site donors
Weng_2019_J.Food.Sci_84_2091 Antioxidant Profile of 1-Monocaffeoyl Glycerol in Lipophobic\/Lipophilic Media
Zhang_2019_Food.Chem_286_29 Interesterification of rice bran wax and palm olein catalyzed by lipase: Crystallization behaviours and characterization
Dzimianski_2019_J.Mol.Biol_431_4203 ISG15: It's Complicated
Hofstetter_2019_Anal.Biochem_585_113400 The conversion of azo-quenchers to fluorophores
Oh_2019_Crystals_9_597 Carboxylic Ester Hydrolases in Bacteria: Active Site, Structure, Function and Application
Golchin-Rad_2019_BMC.Vet.Res_15_440 Changes in specific serum biomarkers during the induction of prostatic hyperplasia in dogs
Murugayah_2019_Biochem.Soc.Trans_47_793 Engineering quorum quenching enzymes: progress and perspectives
Nepovimova_2019_Med.Res.Rev_39_961 Orexin supplementation in narcolepsy treatment: A review
Mosbech_2019_Appl.Microbiol.Biotechnol_103_4065 Enzyme kinetics of fungal glucuronoyl esterases on natural lignin-carbohydrate complexes
Panaro_2019_Mol.Metab_19_65 Fibroblast activation protein is dispensable for control of glucose homeostasis and body weight in mice
Collombel_2019_Front.Microbiol_10_2597 New Insights Into Cinnamoyl Esterase Activity of Oenococcus oeni
Mogodiniyai_2019_Front.Microbiol_10_2673 Identification of Novel Putative Bacterial Feruloyl Esterases From Anaerobic Ecosystems by Use of Whole-Genome Shotgun Metagenomics and Genome Binning
Bhakhoa_2019_R.Soc.Open.Sci_6_181831 Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning
Carlsen_2019_Mol.Inform_38_e1800106 After Salisbury Nerve Agents Revisited
Stone_2019_Science_366_404 Obscure Cold War nerve agents set to be banned
Tan_2019_Molecules_24_ A Scheme for Ultrasensitive Detection of Molecules with Vibrational Spectroscopy in Combination with Signal Processing
Jeru_2019_J.Clin.Endocrinol.Metab_104_6025 Diagnostic Challenge in PLIN1-Associated Familial Partial Lipodystrophy
Chui_2019_Science_364_82 N-terminal degradation activates the NLRP1B inflammasome
Kong_2019_Drug.Metab.Dispos_47_238 Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
Wang_2019_Pharmacology_103_273 Design and Discovery of Novel 1,3,5-Triazines as Dipeptidyl Peptidase-4 Inhibitor against Diabetes
Di_2019_Curr.Drug.Metab_20_91 The Impact of Carboxylesterases in Drug Metabolism and Pharmacokinetics
Latif_2019_Pak.J.Pharm.Sci_32_2311 Neurotoxic effects of titanium dioxide nanoparticles on the brain of male sprague dawley rats
Muangnoi_2019_Pharmaceutics_11_ Scale-Up Synthesis and In Vivo Anti-Tumor Activity of Curcumin Diethyl Disuccinate, an Ester Prodrug of Curcumin, in HepG2-Xenograft Mice
Najjar_2019_Expert.Opin.Drug.Deliv_16_1 The prodrug approach in the era of drug design
Raschmanova_2019_Front.Microbiol_10_335 Single-Cell Approach to Monitor the Unfolded Protein Response During Biotechnological Processes With Pichia pastoris
Sultana_2019_Pak.J.Pharm.Sci_32_143 Efficacy of Chrozophora plicata and Trianthema portuclacastrum weed plant extracts against Trogoderma granarium Everts under laboratory conditions
Mesiti_2019_Eur.J.Med.Chem_181_111572 The chemistry toolbox of multitarget-directed ligands for Alzheimer's disease
Abdali_2019_ACS.Omega_4_4063 Bacteria-Responsive Single and Core-Shell Nanofibrous Membranes Based on Polycaprolactone\/Poly(ethylene succinate) for On-Demand Release of Biocides
Jaroszewicz_2019_Mater.Sci.Eng.C.Mater.Biol.Appl_96_319 Formation of calcium phosphate coatings within polycaprolactone scaffolds by simple, alkaline phosphatase based method
Pakalapati_2019_Enzyme.Microb.Technol_122_7 Optimization and modelling of enzymatic polymerization of sigma-caprolactone to polycaprolactone using Candida Antartica Lipase B with response surface methodology and artificial neural network
Pazarceviren_2019_Biomed.Mater_14_035018 Resorbable PCEC\/gelatin-bismuth doped bioglass-graphene oxide bilayer membranes for guided bone regeneration
Srinivasamurthy_2019_Z.Naturforsch.C.J.Biosci_74_71 A multi-enzyme cascade reaction for the production of 6-hydroxyhexanoic acid
Todea_2019_Polymers.(Basel)_11_ Biodegradable Oligoesters of sigma-Caprolactone and 5-Hydroxymethyl-2-Furancarboxylic Acid Synthesized by Immobilized Lipases
Vaidya_2019_Carbohydr.Polym_217_98 Synthesis of graft copolymers of chitosan-poly(caprolactone) by lipase catalysed reactive extrusion
van Haaften_2019_Acta.Biomater_92_48 The degradation and performance of electrospun supramolecular vascular scaffolds examined upon in vitro enzymatic exposure
Zanetti_2019_Mater.Sci.Eng.C.Mater.Biol.Appl_97_198 Encapsulation of geranyl cinnamate in polycaprolactone nanoparticles
Yoshinaga_2019_J.Oleo.Sci_68_1295 Effects of Heat Treatment on Lactone Content of Butter and Margarine
Travers_2019_Nat.Metab_1_1034 ABHD5 cleaves HDAC4 to benefit the heart
Alapafuja_2019_Bioorg.Med.Chem_27_55 Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment
Kringel_2019_Pain_160_2263 Machine-learned analysis of the association of next-generation sequencing-based genotypes with persistent pain after breast cancer surgery
Lamani_2019_Bioorg.Med.Chem_27_115096 Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology
Otrubova_2019_Bioorg.Med.Chem_27_1693 N-Acyl pyrazoles: Effective and tunable inhibitors of serine hydrolases
Schwenk_2019_Neuron_104_680 An ER Assembly Line of AMPA-Receptors Controls Excitatory Neurotransmission and Its Plasticity
Grevengoed_2019_Proc.Natl.Acad.Sci.U.S.A_116_24770 N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis
Liu_2019_Curr.Mol.Med_19_364 Identifying the Potential Substrates of the Depalmitoylation Enzyme Acyl-protein Thioesterase 1
Pavon_2019_Addict.Biol_24_1204 Ethanol-induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice
Sticht_2019_Br.J.Pharmacol_176_1524 Endocannabinoid regulation of homeostatic feeding and stress-induced alterations in food intake in male rats
Shin_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_907 Lipid-metabolizing serine hydrolases in the mammalian central nervous system: endocannabinoids and beyond
Ballinger_2019_eNeuro_6_ Mecp2 Deletion from Cholinergic Neurons Selectively Impairs Recognition Memory and Disrupts Cholinergic Modulation of the Perirhinal Cortex
Calahorro_2019_J.Exp.Biol_222_ Neuroligin tuning of pharyngeal pumping reveals extrapharyngeal modulation of feeding in Caenorhabditis elegans
Chen_2019_Pharmacol.Res_145_104254 Pharmacological activities of dihydrotanshinone I, a natural product from Salvia miltiorrhiza Bunge
Courties_2019_Joint.Bone.Spine_86_725 The Phenotypic Approach to Osteoarthritis: A Look at Metabolic Syndrome-Associated Osteoarthritis
Greer_2019_Toxicol.Sci_172_146 Effects of Chlorpyrifos on Cholinesterase and Serine Lipase Activities and Lipid Metabolism in Brains of Rainbow Trout (Oncorhynchus mykiss)
Henderson_2019_Parkinsonism.Relat.Disord_61_106 The minimum clinically important difference (MCID) for a falls intervention in Parkinson's: A delphi study
Ilesanmi_2019_J.Basic.Clin.Physiol.Pharmacol_31_ Modulation of key enzymes linked to Parkinsonism and neurologic disorders by Antiaris africana in rotenone-toxified rats
Kim_2019_J.Basic.Clin.Physiol.Pharmacol_31_ The use of Huperzia species for the treatment of Alzheimer's disease
Korabecny_2019_Curr.Med.Chem_26_5625 A Systematic Review on Donepezil-based Derivatives as Potential Cholinesterase Inhibitors for Alzheimer's Disease
Mohseni-Moghaddam_2019_Clin.Exp.Pharmacol.Physiol_46_360 Huperzine A ameliorates cognitive dysfunction and neuroinflammation in kainic acid-induced epileptic rats by antioxidant activity and NLRP3\/caspase-1 pathway inhibition
Nabavi_2019_Curr.Med.Chem_26_3253 Aporphines and Alzheimer's Disease: Towards a Medical Approach Facing the Future
Pina_2019_Toxicol.Sci__ Multi-omic analysis of zebrafish models of acute organophosphorus poisoning with different severity
Rajesh_2019_Protein.Pept.Lett__ Proteome based de novo sequencing of novel conotoxins from marine molluscivorous cone snail Conus amadis and neurological activities of its natural venom in zebrafish model
Rapaka_2019_J.Ayurveda.Integr.Med_10_241 Vitis vinifera acts as anti-Alzheimer's agent by modulating biochemical parameters implicated in cognition and memory
Soheili_2019_J.Cell.Physiol__ Lavandula angustifolia biological characteristics: An in vitro study
Upadhyay_2019_Curr.Drug.Discov.Technol_16_426 Combined Ligand-Based and Structure-Based Virtual Screening Approach for Identification of New Dipeptidyl Peptidase 4 Inhibitors
Wang_2019_Curr.Med.Chem_26_5684 Recent Advances in Multi-target Anti-Alzheimer Disease Compounds (2013 Up to the Present)
Zhao_2019_Toxicol.Sci_171_69 Physiologically based kinetic modelling-facilitated reverse dosimetry to predict in vivo red blood cell acetylcholinesterase inhibition following exposure to chlorpyrifos in the Caucasian and Chinese population
Augusto-Oliveira_2019_Cells_8_ What Do Microglia Really Do in Healthy Adult Brain?
Coupland_2019_JAMA.Intern.Med_179_1084 Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study
Boutry_2019_Curr.Neurol.Neurosci.Rep_19_18 Update on the Genetics of Spastic Paraplegias
Kloth_2019_Plant.Physiol_181_1704 PECTIN ACETYLESTERASE9 Affects the Transcriptome and Metabolome and Delays Aphid Feeding
Blanc_2019_Methods.Mol.Biol_2009_203 SwissPalm 2: Protein S-Palmitoylation Database
Kawashiri_2019_J.Pharmacol.Sci_140_291 Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect
Zhao_2019_Appl.Microbiol.Biotechnol_103_7129 Biodegradation of mycotoxin fumonisin B1 by a novel bacterial consortium SAAS79
Tinsa_2019_J.Pediatr.Hematol.Oncol_41_e193 A Novel Mutation c.153 C>A in a Tunisian Girl With Wolman Disease and Unusual Presentation: Hemophagocytic Lymphohistiocytosis
Bingul_2019_Monatsh.Chem_150_1553 Synthesis of indole-2-carbohydrazides and 2-(indol-2-yl)-1,3,4-oxadiazoles as antioxidants and their acetylcholinesterase inhibition properties
Shamsara_2019_Comb.Chem.High.Throughput.Screen_22_555 A Random Forest Model to Predict the Activity of a Large Set of Soluble Epoxide Hydrolase Inhibitors Solely Based on a Set of Simple Fragmental Descriptors
Waters_2019_Mol.Plant_12_21 Spoilt for Choice: New Options for Inhibitors of Strigolactone Signaling
Ercin_2019_Balkan.Med.J_37_15 Hypoxic Gene Signature of Primary and Metastatic Melanoma Cell Lines: Focusing on HIF-1beta and NDRG-1
Neuhaus_2019_Inflamm.Res_68_529 Lung infection caused by Pseudomonas aeruginosa in a CD26\/DPP4 deficient F344 rat model
Pajed_2019_J.Biol.Chem_294_9118 Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation
Lordan_2019_Molecules_24_ Forty Years Since the Structural Elucidation of Platelet-Activating Factor (PAF): Historical, Current, and Future Research Perspectives
de Las Rivas_2019_Appl.Microbiol.Biotechnol_103_603 Bacterial tannases: classification and biochemical properties
Bourret_2019_Genome.Biol.Evol_11_3523 COUSIN (COdon Usage Similarity INdex): A Normalized Measure of Codon Usage Preferences
De Mesmaeker_2019_Chimia.(Aarau)_73_549 Design, Synthesis and Biological Evaluation of Strigolactone and Strigolactam Derivatives for Potential Crop Enhancement Applications in Modern Agriculture
Ding_2019_Biotechnol.Lett_41_137 Identification and engineering of the key residues at the crevice-like binding site of lipases responsible for activity and substrate specificity
Bis-Brewer_2019_Sci.Rep_9_1692 A network biology approach to unraveling inherited axonopathies
Abdullaev_2019_Ter.Arkh_91_22 [Comparative clinical and economic evaluation of pharmacogenetic testing application for dabigatran in patients with atrial fibrillation]
Cervellati_2019_Minerva.Med_110_238 Evaluating the link between Paraoxonase-1 levels and Alzheimer's disease development
Cervellati_2019_Atherosclerosis_285_64 Paraoxonase-1 activities in individuals with different HDL circulating levels: Implication in reverse cholesterol transport and early vascular damage
Maestri_2019_Nat.Chem_11_1082 Alkenyl boost for Catellani
Meriwether_2019_J.Clin.Invest_129_3670 Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model
Morresi_2019_Cells_8_ Effect of High Glucose-Induced Oxidative Stress on Paraoxonase 2 Expression and Activity in Caco-2 Cells
Rosini_2019_Eur.J.Med.Chem_180_111 Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-beta peptide in Alzheimer's disease
Tisato_2019_Antioxidants.(Basel)_8_ Crosstalk Between Adipokines and Paraoxonase 1: A New Potential Axis Linking Oxidative Stress and Inflammation
Trentini_2019_J.Clin.Biochem.Nutr_64_250 Sex difference: an important issue to consider in epidemiological and clinical studies dealing with serum paraoxonase-1
Cardozo_2019_Molecules_25_ Biodegradation of Organophosphorus Compounds Predicted by Enzymatic Process Using Molecular Modelling and Observed in Soil Samples Through Analytical Techniques and Microbiological Analysis: A Comparison
Qiao_2019_Proc.Natl.Acad.Sci.U.S.A_116_19274 Water follows polar and nonpolar protein surface domains
Weber_2019_Appl.Microbiol.Biotechnol_103_4801 Interaction of carbohydrate-binding modules with poly(ethylene terephthalate)
van Loo_2019_Biochemistry_58_1363 Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase
Jiang_2019_Curr.Med.Chem_26_7081 The Structures and Bioactivities of Fatty Acid Synthase Inhibitors
Tan_2019_Eur.J.Med.Chem_182_111597 Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells
Wang_2019_Am.J.Transl.Res_11_5096 Vitisin B as a novel fatty acid synthase inhibitor induces human breast cancer cells apoptosis
Park_2019_Sci.Adv_5_eaav0316 Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease
Yazdani_2019_Bioorg.Chem_84_363 Multi-target inhibitors against Alzheimer disease derived from 3-hydrazinyl 1,2,4-triazine scaffold containing pendant phenoxy methyl-1,2,3-triazole: Design, synthesis and biological evaluation
Zhu_2019_Bioorg.Med.Chem.Lett_29_126625 The development of 2-acetylphenol-donepezil hybrids as multifunctional agents for the treatment of Alzheimer's disease
Li_2019_Appl.Biochem.Biotechnol_187_424 Identification of a Novel Feruloyl Esterase by Functional Screening of a Soil Metagenomic Library
Tanigushi_2019_ACS.Catal_9_4089 Biodegradation of PET: Current Status and Application Aspects
Alexander_2019_Br.J.Pharmacol_176 Suppl 1_S297 THE CONCISE GUIDE TO PHARMACOLOGY 2019\/20: Enzymes
Freeman_2019_Pestic.Biochem.Physiol_158_61 Insecticide resistance monitoring of house fly populations from the United States
Savelieff_2019_Chem.Rev_119_1221 Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
Ren_2019_Curr.Alzheimer.Res_16_39 Astrocytic alpha7 Nicotinic Receptor Activation Inhibits Amyloid-beta Aggregation by Upregulating Endogenous alphaB-crystallin through the PI3K\/Akt Signaling Pathway
Li_2019_Chemosphere_225_443 Biodegradability and biodegradation pathway of di-(2-ethylhexyl) phthalate by Burkholderia pyrrocinia B1213
Aguillon_2019_Mol.Catal_467_128 Immobilized lipase screening towards continuous-flow kinetic resolution of (+\/-)-1,2-propanediol
Basso_2019_Mol.Catal_479_110607 Industrial applications of immobilized enzymes: A review
Lima_2019_Mol.Catal_466_75 Versatility of Candida antarctica lipase in the amide bond formation applied in organic synthesis and biotechnological processes
Zhang_2019_Mol.Catal_466_146 Kinetic model of the enzymatic Michael addition for synthesis of mitomycin analogs catalyzed by immobilized lipase from T. laibacchii
Galaj_2019_CNS.Drugs_33_1001 Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders
Jin_2019_Int.J.Biol.Macromol_130_342 Preparation of lipase cross-linked enzyme aggregates in octyl-modified mesocellular foams
Li_2019_Enzyme.Microb.Technol_126_41 Enhancing thermostability of Yarrowia lipolytica lipase 2 through engineering multiple disulfide bonds and mitigating reduced lipase production associated with disulfide bonds
Mori_2019_Bioorg.Med.Chem_27_3568 Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[(11)C]carboxylate
Cruz_2019_J.Biomol.Struct.Dyn_37_1616 Molecular dynamics simulation and binding free energy studies of novel leads belonging to the benzofuran class inhibitors of Mycobacterium tuberculosis Polyketide Synthase 13
Heo_2019_Ann.Pediatr.Endocrinol.Metab_24_199 Congenital hypothyroidism due to thyroglobulin deficiency: a case report with a novel mutation in TG gene
Santos-Silva_2019_J.Pediatr.Endocrinol.Metab_32_1265 Genetic analyses in a cohort of Portuguese pediatric patients with congenital hypothyroidism
Aalbers_2019_Chembiochem_20_20 Enzyme Fusions in Biocatalysis: Coupling Reactions by Pairing Enzymes
Rimmer_2019_Bmj_366_l4663 Salisbury novichok attack: five minutes with . . . Christine Blanshard
Vijayaraj_2019_J.Food.Biochem_43_e12774 Cyanidin and cyanidin-3-glucoside derived from Vigna unguiculata act as noncompetitive inhibitors of pancreatic lipase
Hu_2019_Elife_8_e47178 GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
Kumar_2019_J.Mol.Graph.Model_88_92 Investigation of novel chemical scaffolds targeting prolyl oligopeptidase for neurological therapeutics
Maddirevula_2019_Genet.Med_21_736 Autozygome and high throughput confirmation of disease genes candidacy
Natunen_2019_Basic.Clin.Pharmacol.Toxicol_124_40 Extracellular prolyl oligopeptidase derived from activated microglia is a potential neuroprotection target
Norrbacka_2019_J.Cell.Mol.Med_23_8511 Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington's disease
Svarcbahs_2019_Biochem.Pharmacol_161_113 New tricks of prolyl oligopeptidase inhibitors - A common drug therapy for several neurodegenerative diseases
Taroni_2019_Front.Pediatr_7_127 A Case of Hypotonia-Cystinuria Syndrome With Genito-Urinary Malformations and Extrarenal Involvement
Venditti_2019_J.Histochem.Cytochem_67_229 Subcellular Localization of Prolyl Endopeptidase During the First Wave of Rat Spermatogenesis and in Rat and Human Sperm
Amoudji_2019_Malar.J_18_177 Insecticide resistance profiles of Anopheles gambiae s.l. in Togo and genetic mechanisms involved, during 3-year survey: is there any need for resistance management?
Chen_2019_J.Med.Entomol_56_803 Insecticide Resistance Status and Mechanisms of Anopheles sinensis (Diptera: Culicidae) in Wenzhou, an Important Coastal Port City in China
Ibrahim_2019_Infect.Dis.Poverty_8_100 High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic
Namountougou_2019_Acta.Trop_197_105054 Insecticide resistance mechanisms in Anopheles gambiae complex populations from Burkina Faso, West Africa
Opondo_2019_Parasit.Vectors_12_287 Status of insecticide resistance in Anopheles gambiae (s.l.) of The Gambia
Vaulin_2019_J.Vector.Ecol_44_48 Estimated resistance of the malaria mosquito Anopheles messeae s.l. to the insecticide malathion
Williams_2019_Parasit.Vectors_12_522 Characterisation of Anopheles strains used for laboratory screening of new vector control products
Zogo_2019_Parasite_26_40 Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Cte d'Ivoire: a pre-intervention study
Witztum_2019_N.Engl.J.Med_381_531 Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome
Tan_2019_J.Cell.Sci_132_ Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function
Bychkov_2019_Mol.Genet.Metab_127_212 The novel synonymous variant in LIPA gene affects splicing and causes lysosomal acid lipase deficiency
Gomaraschi_2019_Trends.Pharmacol.Sci_40_104 Lysosomal Acid Lipase: From Cellular Lipid Handler to Immunometabolic Target
Li_2019_Arterioscler.Thromb.Vasc.Biol_39_850 Lysosomal Acid Lipase in Lipid Metabolism and Beyond
Steensels_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_79 Fatty acid activation in thermogenic adipose tissue
Strebinger_2019_Hepat.Med_11_79 Lysosomal acid lipase deficiency - early diagnosis is the key