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Year Report for: 2019

Aalbers_2019_Chembiochem_20_20Enzyme Fusions in Biocatalysis: Coupling Reactions by Pairing Enzymes
Abbas_2019_Bioorg.Chem_86_305The management of diabetes mellitus-imperative role of natural products against dipeptidyl peptidase-4, alpha-glucosidase and sodium-dependent glucose co-transporter 2 (SGLT2)
Abbasi_2019_Pak.J.Pharm.Sci_32_2003In vitro assessment of antibacterial, antifungal, enzyme inhibition and hemolytic activities of various fractions of Rhynchosia pseudo-cajan
Abbasi_2019_Pak.J.Pharm.Sci_32_61Synthesis of some new N-(alkyl/aralkyl)-N-(2,3-dihydro-1,4-benzodioxan-6-yl)-4-chlorobenzenesulfonamide s as possible therapeutic agents for Alzheimer's disease and Type-2 Diabetes
Abd El-Rahman_2019_Aquat.Toxicol_217_105329Assessment of hematological, hepato-renal, antioxidant, and hormonal responses of Clarias gariepinus exposed to sub-lethal concentrations of oxyfluorfen
Abd-Elhakim_2019_Food.Chem.Toxicol__111055Camel milk rescues neurotoxic impairments induced by fenpropathrin via regulating oxidative stress, apoptotic, and inflammatory events in the brain of rats
Abdali_2019_ACS.Omega_4_4063Bacteria-Responsive Single and Core-Shell Nanofibrous Membranes Based on Polycaprolactone/Poly(ethylene succinate) for On-Demand Release of Biocides
Abdel-Diam_2019_Environ.Sci.Pollut.Res.Int_26_3659Curcumin and quercetin synergistically attenuate subacute diazinon-induced inflammation and oxidative neurohepatic damage, and acetylcholinesterase inhibition in albino rats
Abdel-Rasoul_2019_Egypt.J.Occup.Med_43_331Neurobehavioral and Menstrual Disorders among Adolescent Females Environmentally Exposed to Pesticides, Menoufia Governorate, Egypt
Abdel-Wahab_2019_Drug.Des.Devel.Ther_13_1155Neuroprotective effect of N-acetylcysteine against cisplatin-induced toxicity in rat brain by modulation of oxidative stress and inflammation
Abdelgaleil_2019_Pestic.Biochem.Physiol_156_105Acaricidal activity, biochemical effects and molecular docking of some monoterpenes against two-spotted spider mite (Tetranychus urticae Koch)
Abdellaoui_2019_Neotrop.Entomol_48_246Olive Leaf Extracts Toxicity to the Migratory Locust, Locusta migratoria: Histopathological Effects on the Alimentary Canal and Acetylcholinesterase and Glutathione S-Transferases Activity
Abdshahzadeh_2019_Chem.Biodivers_16_e18004363-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease
Abdul_2019_Front.Aging.Neurosci_11_206Synergistic Effects of Curcumin and Piperine as Potent Acetylcholine and Amyloidogenic Inhibitors With Significant Neuroprotective Activity in SH-SY5Y Cells via Computational Molecular Modeling and in vitro Assay
Abdullaev_2019_Ter.Arkh_91_22[Comparative clinical and economic evaluation of pharmacogenetic testing application for dabigatran in patients with atrial fibrillation]
Abidar_2019_J.Food.Biochem__e13009Glucose-mediated protein glycation: Contribution of methanolic extract of Ceratonia siliqua L. in protection and in vitro potential inhibition of acetylcholinesterase
Abis_2019_Anal.Chem_91_14865Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase
Abis_2019_Commun.Biol_2_18815-deoxy-Delta(12,14)-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism
Abis_2019_Protein.Expr.Purif_153_105Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain
Abolhassani_2019_Ecotoxicol.Environ.Saf_178_168Organochlorine and organophosphorous pesticides may induce colorectal cancer; A case-control study
Abou_2019_Geriatr.Psychol.Neuropsychiatr.Vieil_17_317Pharmacological management of delusions associated with dementia
Abu-Aisheh_2019_Heliyon_5_e01552Coumarin derivatives as acetyl- and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics simulations study
Abu-Farha_2019_Sci.Rep_9_11866Reduced miR-181d level in obesity and its role in lipid metabolism via regulation of ANGPTL3
Abu-Taweel_2019_Saudi.J.Biol.Sci_26_736Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring
Acar_2019_Molecules_24_Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives
Acet_2019_J.Food.Biochem__e13128An assessment of phenolic profiles, fatty acid compositions, and biological activities of two Helichrysum species: H. plicatum and H. chionophilum
Aceves_2019_Eur.J.Neurosci_49_824Selective remodeling of glutamatergic transmission to striatal cholinergic interneurons after dopamine depletion
Adedara_2019_Environ.Toxicol.Pharmacol_73_103294Neurobehavioural and biochemical responses associated with exposure to binary waterborne mixtures of zinc and nickel in rats
Adedara_2019_Food.Chem.Toxicol_125_170Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats
Adefegha_2019_Drug.Chem.Toxicol__1Thyme (Thymus vulgaris) leaf extract modulates purinergic and cholinergic enzyme activities in the brain homogenate of 5-fluorouracil administered rats
Ademiluyi_2019_J.Food.Biochem_43_e12815Phenolic analysis and erectogenic function of African Walnut (Tetracarpidium conophorum) seeds: The impact of the seed shell on biological activity
Ademosun_2019_Andrologia__e13371Orange peels modulate antioxidant markers and key enzymes relevant to erection in the penile tissue of paroxetine-treated rats
Ademosun_2019_Biomed.Pharmacother_111_1029Anogeissus leiocarpus attenuates paroxetine-induced erectile dysfunction in male rats via enhanced sexual behavior, nitric oxide level and antioxidant status
Adessi_2019_Chem.Biodivers_16_e1800662Clinanthus microstephium, an Amaryllidaceae Species with Cholinesterase Inhibitor Alkaloids: Structure-Activity Analysis of Haemanthamine Skeleton Derivatives
Adeyinka_2019_Sci.Rep_9_13629Identification and validation of potential reference gene for effective dsRNA knockdown analysis in Chilo partellus
Ado_2019_Nat.Prod.Res__1Acetylcholinesterase and alpha-glucosidase inhibitory compounds from Callicarpa maingayi
Afzali_2019_Caspian.J.Intern.Med_10_458Butyrylcholinesterase level in poisoned patients with phosphide compounds
Agatonovic-Kustrin_2019_Mar.Drugs_17_High-Performance Thin-Layer Chromatography Hyphenated with Microchemical and Biochemical Derivatizations in Bioactivity Profiling of Marine Species
Agatonovic-Kustrin_2019_Neural.Regen.Res_14_441Essential oils and functional herbs for healthy aging
Agbo_2019_Molecules_24_Inhibitory Effects of Novel 7-Substituted 6-iodo-3-O-Flavonol Glycosides against Cholinesterases and beta-secretase Activities, and Evaluation for Potential Antioxidant Properties
Aghoutane_2019_Bioelectrochemistry_132_107404Development of a molecularly imprinted polymer electrochemical sensor and its application for sensitive detection and determination of malathion in olive fruits and oils
Aguillon_2019_Mol.Catal_467_128Immobilized lipase screening towards continuous-flow kinetic resolution of (+/-)-1,2-propanediol
Ah_2019_Basic.Clin.Pharmacol.Toxicol_124_741Effect of anticholinergic burden on treatment modification, delirium and mortality in newly diagnosed dementia patients starting a cholinesterase inhibitor: A population-based study
Ahmad_2019_Bioorg.Chem_92_103216Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs
Ahmad_2019_Drug.Des.Devel.Ther_13_4185Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies
Ahmad_2019_Nat.Prod.Res__1Phenolic, flavonoid content and radical scavenging activity of Smilax China with its inhibitory potential against clinically important enzymes
Ahmad_2019_Polym.Degrad.Stab_164_109Gene structure and comparative study of two different plastic-degrading esterases fromRoseateles depolymeransstrain TB-87
Ahmadi-Motamayel_2019_Spec.Care.Dentist_39_39Evaluation of salivary acetylcholinesterase and pseudocholinesterase in patients with Alzheimer's disease: A case-control study
Ahmed-Chaouch_2019_Nat.Prod.Res__1Chemical composition, in vitro antioxidant, anticholinesterase and antibacterial activities of Linaria scariosa Desf
Ahmed_2019_Drugs.Aging_36_589Current Agents in Development for Treating Behavioral and Psychological Symptoms Associated with Dementia
Ahren_2019_Front.Endocrinol.(Lausanne)_10_376DPP-4 Inhibition and the Path to Clinical Proof
Ahuja_2019_Pharmacol.Rep_71_614Alpha lipoic acid and metformin alleviates experimentally induced insulin resistance and cognitive deficit by modulation of TLR2 signalling
Ajayi_2019_J.Ethnopharmacol_231_503Acetylcholinesterase inhibitor from Anthocleista vogelii leaf extracts
Ajayi_2019_Toxicol.Rep_6_656Evaluation of neurotoxicity and hepatotoxicity effects of acute and sub-acute oral administration of unripe ackee (Blighia sapida) fruit extract
Ajiboye_2019_J.Basic.Clin.Physiol.Pharmacol_31_In vitro antioxidant and enzyme inhibitory properties of the n-butanol fraction of Senna podocarpa (Guill. and Perr.) leaf
Akdeniz_2019_J.Food.Biochem__e13124Phytochemical and biological investigations on two Nepeta species: Nepeta heliotropifolia and N. congesta subsp. cryptantha
Akinrinde_2019_Neurotoxicol_74_252Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats
Akintade_2019_Clin.Med.(Lond)_19_327Acute presentation of dementia with Lewy bodies
Akintunde_2019_Biochem.Biophys.Rep_17_97Metabolic treatment of syndrome linked with Parkinson's disease and hypothalamus pituitary gonadal hormones by turmeric curcumin in Bisphenol-A induced neuro-testicular dysfunction of wistar rat
AlFadly_2019_Eur.J.Med.Chem_167_161Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
Alabi_2019_Neurotoxicol_74_172Methyl jasmonate abrogates rotenone-induced parkinsonian-like symptoms through inhibition of oxidative stress, release of pro-inflammatory cytokines, and down-regulation of immnopositive cells of NF-kappaB and alpha-synuclein expressions in mice
Alak_2019_Chemosphere_221_30Therapeutic effect of N- acetyl cysteine as an antioxidant on rainbow trout's brain in cypermethrin toxicity
Alali_2019_Chemistry_25_11892HFIP-Functionalized Co3 O4 Micro-Nano-Octahedra/rGO as a Double-Layer Sensing Material for Chemical Warfare Agents
Alam_2019_Curr.Drug.Targets_20_316Potential Enzymatic Targets in Alzheimer's: A Comprehensive Review
Alapafuja_2019_Bioorg.Med.Chem_27_55Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment
Alavinia_2019_Ecotoxicol.Environ.Saf_182_109311DNA damage, acetylcholinesterase activity, and hematological responses in rainbow trout exposed to the organophosphate malathion
Alberts_2019_Toxins.(Basel)_11_523Detoxification of the Fumonisin Mycotoxins in Maize: An Enzymatic Approach
Albishri_2019_Talanta_200_107Hyphenation of enzyme/graphene oxide-ionic liquid/glassy carbon biosensors with anodic differential pulse stripping voltammetry for reliable determination of choline and acetylcholine in human serum
Alexander_2019_Br.J.Pharmacol_176 Suppl 1_S297THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes
Alfaro-Chavez_2019_Protein.Eng.Des.Sel_32_13Improving on nature's shortcomings: evolving a lipase for increased lipolytic activity, expression and thermostability
Algaissi_2019_J.Infect.Dis_219_829Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease
Ali-Shtayeh_2019_Evid.Based.Complement.Alternat.Med_2019_3834265Biological Properties and Bioactive Components of Mentha spicata L. Essential Oil: Focus on Potential Benefits in the Treatment of Obesity, Alzheimer's Disease, Dermatophytosis, and Drug-Resistant Infections
Ali_2019_Chem.Biol.Interact_309_108707Flavanone glycosides inhibit beta-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Abeta aggregation in the amyloidogenic pathway
Ali_2019_Int.J.Mol.Sci_20_Identification and Evaluation of Inhibitors of Lipase from Malassezia restricta using Virtual High-Throughput Screening and Molecular Dynamics Studies
Ali_2019_Mol.Clin.Oncol_10_118A multi-center retrospective analysis of the effect of DPP4 inhibitors on progression-free survival in advanced airway and colorectal cancers
Ali_2019_Toxicol.Appl.Pharmacol_363_154Bone loss in MPTP mouse model of Parkinson's disease is triggered by decreased osteoblastogenesis and increased osteoclastogenesis
Allan_2019_J.Lipid.Res_60_869An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner
Almansour_2019_Bioorg.Med.Chem.Lett__126789Design, synthesis and cholinesterase inhibitory activity of novel spiropyrrolidine tethered imidazole heterocyclic hybrids
Almeida_2019_Ecotoxicol.Environ.Saf_186_109760Biochemical and behavioral responses of zebrafish embryos to magnetic graphene/nickel nanocomposites
Almeida_2019_Environ.Sci.Pollut.Res.Int_26_9823Effects of acetaminophen in oxidative stress and neurotoxicity biomarkers of the gastropod Phorcus lineatus
Almeida_2019_Front.Microbiol_10_2187In silico Screening and Heterologous Expression of a Polyethylene Terephthalate Hydrolase (PETase)-Like Enzyme (SM14est) With Polycaprolactone (PCL)-Degrading Activity, From the Marine Sponge-Derived Strain Streptomyces sp. SM14
Almeida_2019_Int.J.Biol.Macromol_137_442Biochemical characterization and application of a new lipase and its cognate foldase obtained from a metagenomic library derived from fat-contaminated soil
Almenares-Lopez_2019_Chem.Biol.Interact_13ChEPon_308_252Copper(II)-dependent hydrolysis of trichloronate by turkey serum albumin
Alonso_2020_Nat.Catal_3_319Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Altay_2019_J.Food.Biochem_43_e12908Preliminary phytochemical analysis and evaluation of in vitro antioxidant, antiproliferative, antidiabetic, and anticholinergics effects of endemic Gypsophila taxa from Turkey
Alvarado_2019_J.Biomol.Struct.Dyn__1Understanding the Enzyme-Ligand Complex: Insights from All-Atom Simulations of Butyrylcholinesterase Inhibition
Alves_2019_Front.Microbiol_10_1571Ammonia Oxidation by the Arctic Terrestrial Thaumarchaeote Candidatus Nitrosocosmicus arcticus Is Stimulated by Increasing Temperatures
Alves_2019_Mar.Drugs_17_A New Meroterpene, A New Benzofuran Derivative and Other Constituents from Cultures of the Marine Sponge-Associated Fungus Acremonium persicinum KUFA 1007 and Their Anticholinesterase Activities
Alzu'bi_2019_Cereb.Cortex_29_1706Thalamocortical Afferents Innervate the Cortical Subplate much Earlier in Development in Primate than in Rodent
Amara_2019_Cell.Chem.Biol_26_35Synthetic Fluorogenic Peptides Reveal Dynamic Substrate Specificity of Depalmitoylases
Amara_2019_Environ.Sci.Pollut.Res.Int_26_7540Di (2-ethylhexyl) phthalate induces cardiac disorders in BALB/c mice
Ambartsumyan_2019_Pediatr.Dev.Pathol__1093526619892351Diagnosis of Hirschsprung Disease
Amelia-Yap_2019_J.Med.Entomol_56_811Pyrethroids Use: Threats on Metabolic-Mediated Resistance Mechanisms in the Primary Dengue Vector Aedes aegypti (Diptera: Culicidae)
Amend_2019_Toxicol.Lett_308_1The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - A proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM)
Ammar_2019_J.Assist.Reprod.Genet_36_2367Novel association between apoptotic sperm biomarkers with seminal biochemical parameters and acetylcholinesterase activity in patients with teratozoospermia
Amornlertwatana_2019_J.Med.Case.Rep_13_327Heroin overdose masquerades as methomyl poisoning: a case report
An_2019_Nutrients_11_Ginsenosides Rg5 and Rk1 Enriched Cultured Wild Ginseng Root Extract Bioconversion of Pediococcus pentosaceus HLJG0702: Effect on Scopolamine-Induced Memory Dysfunction in Mice
Anadozie_2019_J.Basic.Clin.Physiol.Pharmacol_30_Prevention of short-term memory impairment by Bryophyllum pinnatum (Lam.) Oken and its effect on acetylcholinesterase changes in CCl4-induced neurotoxicity in rats
Anderluh_2019_Pharmacol.Ther_201_1DPP-4 inhibition: capital A, Cyrillic novel therapeutic approach to the treatment of pulmonary hypertension?
Anderson_2019_CNS.Spectr__1State of the science on mild cognitive impairment (MCI)
Andersson_2019_Anaesthesia_74_518Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review
Anesti_2019_Epilepsy.Behav_102_106632Effect of rutin on anxiety-like behavior and activity of acetylcholinesterase isoforms in specific brain regions of pentylenetetrazol-treated mice
Anjum_2019_Environ.Sci.Pollut.Res.Int_26_6378Butyrylcholinesterase-a potential plasma biomarker in manganese-induced neurobehavioral changes
Antonijevic_2019_Chem.Biol.Interact_13ChEPon_308_385Comparison of oximes K203 and K027 based on Benchmark dose analysis of rat diaphragmal acetylcholinesterase reactivation
Antonopoulou_2019_Enzyme.Microb.Technol_120_124Screening of novel feruloyl esterases from Talaromyces wortmannii for the development of efficient and sustainable syntheses of feruloyl derivatives
Aoyama_2019_Bioorg.Med.Chem.Lett__126888Selective acetylcholinesterase inhibitors derived from muscle relaxant dantrolene
Appelt_2019_Comp.Immunol.Microbiol.Infect.Dis_66_101330Cholinesterase as an inflammatory marker of subclinical infection of dairy cows infected by Neospora caninum and risk factors for disease
Arai_2019_J.Biosci.Bioeng_127_222Structural characterization of hemicellulose released from corn cob in continuous flow type hydrothermal reactor
Araki_2019_Proc.Natl.Acad.Sci.U.S.A_116_8269Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum
Aras_2019_Chem.Biodivers_16_e1900341Phytochemical Content, Antidiabetic, Anticholinergic, and Antioxidant Activities of Endemic Lecokia cretica Extracts
Araujo_2019_Chemosphere_235_885Effects of triclosan on early development of Solea senegalensis: from biochemical to individual level
Araujo_2019_Ecotoxicol.Environ.Saf_178_230Toxicity of lead and mancozeb differs in two monophyletic Daphnia species
Araujo_2019_Front.Neuroanat_13_36Cyto- and Myelo-Architecture of the Amygdaloid Complex of the Common Marmoset Monkey (Callithrix jacchus)
Arens_2019_J.Med.Toxicol_15_184Adverse Effects of Physostigmine
Arianna_2019_Exp.Gerontol__110754Erythrocyte membrane fluidity in mild cognitive impairment and Alzheimer's disease patients
Armitage_2019_Front.Microbiol_10_3124Genomics Evolutionary History and Diagnostics of the Alternaria alternata Species Group Including Apple and Asian Pear Pathotypes
Armocida_2019_Acta.Med.Hist.Adriat_17_91The Acetylcholine Therapy in the Treatment of Schizophrenia - The Experience of Mario Fiamberti in the Hospital of Varese (1937)
Arnling Baath_2019_J.Biol.Chem_294_6635Structure-function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds
Aroniadou-Anderjaska_2019_Neurobiol.Dis__104406Targeting the glutamatergic system to counteract organophosphate poisoning: A novel therapeutic strategy
Arora_2019_Proc.Natl.Acad.Sci.U.S.A_116_10360Structure of lipoprotein lipase in complex with GPIHBP1
Arque_2019_Nat.Commun_10_2826Intrinsic enzymatic properties modulate the self-propulsion of micromotors
Arslan_2019_Bioorg.Chem_90_103100Triazole substituted metal-free, metallo-phthalocyanines and their water soluble derivatives as potential cholinesterases inhibitors: Design, synthesis and in vitro inhibition study
Arumugam_2019_Bioorg.Med.Chem_27_2621Dispiropyrrolidinyl-piperidone embedded indeno[1,2-b]quinoxaline heterocyclic hybrids: Synthesis, cholinesterase inhibitory activity and their molecular docking simulation
Arvanitakis_2019_JAMA_322_1589Diagnosis and Management of Dementia: Review
Arvaniti_2019_Food.Res.Int_119_244Review on fresh and dried figs: Chemical analysis and occurrence of phytochemical compounds, antioxidant capacity and health effects
Asadi_2019_Chem.Biodivers_16_e1900370Design, Synthesis, Molecular Docking, and Cholinesterase Inhibitory Potential of Phthalimide-Dithiocarbamate Hybrids as New Agents for Treatment of Alzheimer's Disease
Asano_2019_J.Dermatol_46_e19Identification of a novel splice site mutation in the LIPH gene in a Japanese family with autosomal recessive woolly hair
Ashmawy_2019_Molecules_24_Novel Carbon/PEDOT/PSS-Based Screen-Printed Biosensors for Acetylcholine Neurotransmitter and Acetylcholinesterase Detection in Human Serum
Asmat_2019_Mater.Sci.Eng.C.Mater.Biol.Appl_99_25A robust nanobiocatalyst based on high performance lipase immobilized to novel synthesised poly(o-toluidine) functionalized magnetic nanocomposite: Sterling stability and application
Aswani_2019_Sci.Rep_9_19762Biochemical adaptation in brain Acetylcholinesterase during acclimation to sub-lethal temperatures in the eurythermal fish Tilapia mossambica
Aswathi_2019_Bioresour.Technol_292_122025Rapid degradation of the organophosphate pesticide - Chlorpyrifos by a novel strain of Pseudomonas nitroreducens AR-3
Atatreh_2019_J.Enzyme.Inhib.Med.Chem_34_1373Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening
Atkinson_2019_Bioorg.Med.Chem.Lett__126751Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors
Atkinson_2019_Medchemcomm_10_1361Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen
Atmaca_2019_Arch.Pharm.(Weinheim)__e1900200Synthesis of beta-amino acid derivatives and their inhibitory profiles against some metabolic enzymes
Atmaca_2019_Bioorg.Chem_88_102980Synthesis of oxazolidinone from enantiomerically enriched allylic alcohols and determination of their molecular docking and biologic activities
Atri_2019_Semin.Neurol_39_227Current and Future Treatments in Alzheimer's Disease
Atyame_2019_Proc.Biol.Sci_286_20182273Insecticide resistance genes affect Culex quinquefasciatus vector competence for West Nile virus
Augusto-Oliveira_2019_Cells_8_What Do Microglia Really Do in Healthy Adult Brain?
Aulakh_2019_Plant.Physiol_180_1962The Plastid Lipase PLIP1 Is Critical for Seed Viability in diacylglycerol acyltransferase1 Mutant Seed
Aupperle-Lellbach_2019_J.Comp.Pathol_173_71Characterization of 22 Canine Pancreatic Carcinomas and Review of Literature
Auti_2019_Front.Neurol_10_399Neuroprotective Effect of Cardamom Oil Against Aluminum Induced Neurotoxicity in Rats
Ay Sal_2019_Mol.Biol.Rep_46_4385Biochemical characterization of a novel thermostable feruloyl esterase from Geobacillus thermoglucosidasius DSM 2542(T)
Ayaz_2019_Front.Aging.Neurosci_11_155Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders
Ayob_2019_BMC.Anesthesiol_19_25Pre-operative biomarkers and imaging tests as predictors of post-operative delirium in non-cardiac surgical patients: a systematic review
Azadniya_2019_J.Chromatogr.A_1602_458Automated piezoelectric spraying of biological and enzymatic assays for effect-directed analysis of planar chromatograms
Azizi_2019_Acc.Chem.Res_52_3029Activity-Based Sensing of S-Depalmitoylases: Chemical Technologies and Biological Discovery
Azuma_2019_Circ.Cardiovasc.Interv_12_e008015Predictive Model for Mortality Risk Including the Wound, Ischemia, Foot Infection Classification in Patients Undergoing Revascularization for Critical Limb Ischemia
Azzolin_2019_Toxicol.In.Vitro_60_237The Val16Ala-SOD2 polymorphism affects cyto-genotoxicity of pyridostigmine bromide on human peripheral blood mononuclear cells
Baakman_2019_Alzheimers.Dement.(N.Y)_5_89No synergistic effect of subtherapeutic doses of donepezil and EVP-6124 in healthy elderly subjects in a scopolamine challenge model
Bacalhau_2019_Bioorg.Med.Chem_27_354In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor
Bachmann_2019_Invest.Ophthalmol.Vis.Sci_60_4759IPL Sublamination in Chicken Retinal Spheroids Is Initiated via Muller Cells and Cholinergic Differentiation, and Is Disrupted by NMDA Signaling
Bachmann_2019_Transl.Psychiatry_9_29Behavioral training rescues motor deficits in Cyfip1 haploinsufficiency mouse model of autism spectrum disorders
Bachurin_2019_Sci.Rep_9_4873Conjugates of methylene blue with gamma-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases
Badaoui_2019_Nat.Prod.Res__1Pyrroloquinolone A, a new alkaloid and other phytochemicals from Atractylis cancellata L. with antioxidant and anticholinesterase activities
Badawy_2019_Toxicol.Mech.Methods__1Validation and kinetic of enzymatic method for the detection of organophosphate insecticides based on cholinesterase inhibition
Baggelaar_2019_ACS.Chem.Biol_14_2295ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction
Bagheri_2019_Biosens.Bioelectron_134_97A 96-well wax printed Prussian Blue paper for the visual determination of cholinesterase activity in human serum
Bai_2019_Eur.J.Med.Chem_183_111737Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease
Bai_2019_Pestic.Biochem.Physiol_157_69Identification and biochemical characterization of carboxylesterase 001G associated with insecticide detoxification in Helicoverpa armigera
Bajda_2019_Eur.J.Med.Chem_185_111785Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands
Bajgar_2019_Mini.Rev.Med.Chem_19_970Some Possibilities to Study New Prophylactics against Nerve Agents
Bak_2019_Int.J.Mol.Sci_20_1524Novel Benzene-Based Carbamates for AChE/BChE Inhibition: Synthesis and Ligand/Structure-Oriented SAR Study
Bak_2019_Int.J.Mol.Sci_20_5385SAR-mediated Similarity Assessment of the Property Profile for New, Silicon-Based AChE/BChE Inhibitors
Bal_2019_Bioorg.Chem__103468Novel 2-methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties
Baldeweg_2019_Org.Lett_21_1444Fungal Biosurfactants from Mortierella alpina
Baldissera_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__108674Diphenyl diselenide dietary supplementation alleviates behavior impairment and brain damage in grass carp (Ctenopharyngodon idella) exposed to methylmercury chloride
Bali_2019_Toxicology_415_18Learning and memory impairments associated to acetylcholinesterase inhibition and oxidative stress following glyphosate based-herbicide exposure in mice
Balkrishna_2019_Molecules_24_Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study
Ballinger_2019_eNeuro_6_Mecp2 Deletion from Cholinergic Neurons Selectively Impairs Recognition Memory and Disrupts Cholinergic Modulation of the Perirhinal Cortex
Baluchnejadmojarad_2019_Metab.Brain.Dis_34_1747Safranal, an active ingredient of saffron, attenuates cognitive deficits in amyloid beta-induced rat model of Alzheimer's disease: underlying mechanisms
Bampi_2019_Pharmacol.Biochem.Behav_183_46Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice
Banaee_2019_Chemosphere_236_124335Evaluation of single and combined effects of cadmium and micro-plastic particles on biochemical and immunological parameters of common carp (Cyprinus carpio)
Banaee_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_220_62Sub-lethal effects of dimethoate alone and in combination with cadmium on biochemical parameters in freshwater snail, Galba truncatula
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Chaudhary_2019_Development_146_Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wing
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Chen_2019_ACS.Nano_13_7209Cell-Membrane-Cloaked Oil Nanosponges Enable Dual-Modal Detoxification
Chen_2019_Alzheimers.Dement.(N.Y)_5_38The Alzheimer's disease THErapy with NEuroaid (ATHENE) study protocol: Assessing the safety and efficacy of Neuroaid II (MLC901) in patients with mild-to-moderate Alzheimer's disease stable on cholinesterase inhibitors or memantine-A randomized, double-blind, placebo-controlled trial
Chen_2019_Analyst_144_559Thiol-ene click reaction-induced fluorescence enhancement by altering the radiative rate for assaying butyrylcholinesterase activity
Chen_2019_Angew.Chem.Int.Ed.Engl_58_5643Fluorescent Triazole Urea Activity-Based Probes for the Single-Cell Phenotypic Characterization of Staphylococcus aureus
Chen_2019_Antioxidants.(Basel)_8_Assessment of In Vitro Bioactivities of Polysaccharides Isolated from Hericium Novae-Zealandiae
Chen_2019_Biol.Chem_401_165Synthetic and biological approaches to map substrate specificities of proteases
Chen_2019_Biomed.Res.Int_2019_4862647Ester-Producing Mechanism of Ethanol O-acyltransferase EHT1 Gene in Pichia pastoris from Shanxi Aged Vinegar
Chen_2019_Chem.Biol.Interact_13ChEPon_306_89Development of a long-acting Fc-fused cocaine hydrolase with improved yield of protein expression
Chen_2019_Chemosphere_236_124365Spectroscopic and molecular modeling investigation on inhibition effect of nitroaromatic compounds on acetylcholinesterase activity
Chen_2019_Clin.Interv.Aging_14_1243Different durations of cognitive stimulation therapy for Alzheimer's disease: a systematic review and meta-analysis
Chen_2019_Fish.Shellfish.Immunol_97_283Subchronic effects of dietary selenium yeast and selenite on growth performance and the immune and antioxidant systems in Nile tilapia Oreochromis niloticus
Chen_2019_Foods_8_Preventive Effects of Different Fermentation Times of Shuidouchi on Diphenoxylate-Induced Constipation in Mice
Chen_2019_G3.(Bethesda)_9_2051Sequencing of a Wild Apple (Malus baccata) Genome Unravels the Differences Between Cultivated and Wild Apple Species Regarding Disease Resistance and Cold Tolerance
Chen_2019_Insect.Sci_26_843Insecticide toxicity associated with detoxification enzymes and genes related to transcription of cuticular melanization among color morphs of Asian citrus psyllid
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Chen_2019_Int.J.Biol.Macromol_139_298Two novel lipases purified from rice bran displaying lipolytic and esterification activities
Chen_2019_Int.J.Mol.Med_43_91MicroRNA-98 reduces amyloid beta-protein production and improves oxidative stress and mitochondrial dysfunction through the Notch signaling pathway via HEY2 in Alzheimer's disease mice
Chen_2019_J.Clin.Med_8_Serum Level and Activity of Butylcholinesterase: A Biomarker for Post-Stroke Dementia
Chen_2019_J.Ginseng.Res_43_499Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments
Chen_2019_J.Med.Chem_62_3336Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton
Chen_2019_J.Med.Chem_62_8866Design, Synthesis, and Evaluation of (18)F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes
Chen_2019_J.Med.Food_22_1009Effects of Bread Yeast Cell Wall Beta-Glucans on Mice with Loperamide-Induced Constipation
Chen_2019_J.Oleo.Sci_68_1125Highly Selective Synthesis of Monolaurin via Enzymatic Transesterification under Batch and Continuous Flow Conditions
Chen_2019_J.Sep.Sci_42_650Preparative separation of the flavonoid fractions from Periploca forrestii Schltr. ethanol extracts using macroporous resin combined with HPLC analysis and evaluation of their biological activities
Chen_2019_Medicine.(Baltimore)_98_e14371Manifestations of and risk factors for acute myocardial injury after acute organophosphorus pesticide poisoning
Chen_2019_Mol.Divers_23_709Hybrids of oxoisoaporphine-tetrahydroisoquinoline: novel multi-target inhibitors of inflammation and amyloid-beta aggregation in Alzheimer's disease
Chen_2019_Mol.Med.Rep_20_1085Significant association between GPR50 hypomethylation and AD in males
Chen_2019_Nat.Chem.Biol_15_453Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan
Chen_2019_Pestic.Biochem.Physiol_154_32Plant allelochemicals affect tolerance of polyphagous lepidopteran pest Helicoverpa armigera (Hubner) against insecticides
Chen_2019_Pharmacol.Res_145_104254Pharmacological activities of dihydrotanshinone I, a natural product from Salvia miltiorrhiza Bunge
Chen_2019_Proc.Natl.Acad.Sci.U.S.A_116_3764Bacterial lipolysis of immune-activating ligands promotes evasion of innate defenses
Chen_2019_Theranostics_9_7359Carboxylesterase-Cleavable Biotinylated Nanoparticle for Tumor-Dual Targeted Imaging
Chen_2019_Zootaxa_4568_zootaxa 4568 1 9Two new species of marine flatworm from southern China facilitate determination of the phylogenetic position of the genus Nerpa Marcus, 1948 and the histochemical structure of the nervous system in the genus Paucumara Sluys, 1989 (Platyhelminthes, Tricladida, Maricola)
Cheng_2019_ACS.Chem.Neurosci_10_3500Tacrine-Hydrogen Sulfide Donor Hybrid Ameliorates Cognitive Impairment in the Aluminum Chloride Mouse Model of Alzheimer's Disease
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Chetoui_2019_Drug.Chem.Toxicol__1Exposure of Mactra corallina to acute doses of lead: effects on redox status, fatty acid composition and histomorphological aspect
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Chiroma_2019_Toxics_7_Protective Effects of Centella asiatica on Cognitive Deficits Induced by D-gal/AlCl(3) via Inhibition of Oxidative Stress and Attenuation of Acetylcholinesterase Level
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Chrast_2019_Microorganisms_7_Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17
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Cui_2019_Biosens.Bioelectron_141_111452An acetylcholinesterase biosensor based on doping Au nanorod@SiO2 nanoparticles into TiO2-chitosan hydrogel for detection of organophosphate pesticides
Cui_2019_Cancer.Genet_239_54A new prognostic factor of breast cancer: High carboxyl ester lipase expression related to poor survival
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Dai_2019_Anat.Sci.Int_94_128The distribution of nerves supplying the testis, epididymis and accessory sex glands of Suncus murinus
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Daniel_2019_Int.J.Mol.Sci_20_Differentially Expressed Mitochondrial Proteins in Human MCF7 Breast Cancer Cells Resistant to Paclitaxel
Danso_2019_Appl.Environ.Microbiol_85_e01095Plastics: Environmental and Biotechnological Perspectives on Microbial Degradation
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Dato_2019_Bioorg.Chem__103352omega-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase
Daud_2019_Mol.Biotechnol_61_477A Novel Mini Protein Design of Haloalkane Dehalogenase
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De Mesmaeker_2019_Chimia.(Aarau)_73_549Design, Synthesis and Biological Evaluation of Strigolactone and Strigolactam Derivatives for Potential Crop Enhancement Applications in Modern Agriculture
De Simone_2019_J.Pharm.Biomed.Anal_178_112899Advanced analytical methodologies in Alzheimer's disease drug discovery
DeVito_2019_J.Subst.Abuse.Treat_107_29Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder
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Deb_2019_Ecotoxicol.Environ.Saf__109988Bioactivity and efficacy of essential oils extracted from Artemisia annua against Tribolium casteneum (Herbst. 1797) (Coleoptera: Tenebrionidae): An eco-friendly approach
Del_2019_Hum.Mutat_40_2007Large-scale functional LIPA variant characterization to improve birth prevalence estimates of lysosomal acid lipase deficiency
Delnat_2019_Aquat.Toxicol_211_38Whether warming magnifies the toxicity of a pesticide is strongly dependent on the concentration and the null model
Deng_2019_Bioorg.Chem__103366Optimization of the benzamide fragment targeting the S2' site leads to potent dipeptidyl peptidase-IV inhibitors
Deng_2019_Cancer.Cell.Int_19_273Role of XIAP gene overexpressed bone marrow mesenchymal stem cells in the treatment of cerebral injury in rats with cerebral palsy
Deng_2019_Int.J.Biol.Macromol_138_272Expression and characterisation of feruloyl esterases from Lactobacillus fermentum JN248 and release of ferulic acid from wheat bran
Deng_2019_J.Ethnopharmacol_236_288In vivo and in vitro metabolism and pharmacokinetics of cholinesterase inhibitor deoxyvasicine from aerial parts of Peganum harmala Linn in rats via UPLC-ESI-QTOF-MS and UPLC-ESI-MS/MS
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Deng_2019_Phytomedicine_63_153007Ameliorative effect of deoxyvasicine on scopolamine-induced cognitive dysfunction by restoration of cholinergic function in mice
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Deveci_2019_J.Food.Biochem_43_e12965Structural characterization and determination of biological activities for different polysaccharides extracted from tree mushroom species
Deveci_2019_J.Food.Biochem__e13074Isolation, characterization, and bioactivities of compounds from Fuscoporia torulosa mushroom
Deveci_2019_J.Food.Biochem__e13078Phytochemical contents, antioxidant effects, and inhibitory activities of key enzymes associated with Alzheimer's disease, ulcer, and skin disorders of Sideritis albiflora and Sideritis leptoclada
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Diaz-Resendiz_2019_Fish.Shellfish.Immunol_89_12Effect of diazinon, an organophosphate pesticide, on signal transduction and death induction in mononuclear cells of Nile tilapia fish (Oreochromis niloticus)
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Ding_2019_Biosens.Bioelectron__111867Ultrasensitive and visible light-responsive photoelectrochemical aptasensor for edifenphos based on Zinc phthalocyanine sensitized MoS2 nanosheets
Ding_2019_Biotechnol.Lett_41_1059Identification and characterization of an acetyl esterase from Paenibacillus sp. XW-6-66 and its novel function in 7-aminocephalosporanic acid deacetylation
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Ding_2019_J.Appl.Microbiol_127_985Characterization and identification of ferulic acid esterase-producing Lactobacillus species isolated from Elymus nutans silage and their application in ensiled alfalfa
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Dionisio_2019_Environ.Toxicol.Pharmacol_74_103295Multi-parametric analysis of ciprofloxacin toxicity at ecologically relevant levels: Short- and long-term effects on Daphnia magna
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Domingues_2019_Front.Mol.Neurosci_12_325Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism
Dong_2019_Drug.Deliv_26_416Application and design of esterase-responsive nanoparticles for cancer therapy
Dong_2019_Food.Chem_283_508Assessment of phthalate ester residues and distribution patterns in Baijiu raw materials and Baijiu
Dong_2019_J.Biosci.Bioeng_128_525Improving the acetylcholinesterase inhibitory effect of Illigera aromatica by fermentation with Clonostachys rogersoniana
Dong_2019_Molecules_24_Three New 2-(2-Phenylethyl)chromone Derivatives of Agarwood Originated from Gyrinops salicifolia
Dong_2019_Sci.Total.Environ_653_1395Molecular and phenotypic responses of male crucian carp (Carassius auratus) exposed to perfluorooctanoic acid
Dorababu_2019_Bioorg.Chem_93_103299Critical evaluation of current Alzheimer's drug discovery (2018-19) & futuristic Alzheimer drug model approach
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Dos Santos_2019_Food.Funct_10_573The nanoencapsulation of curcuminoids extracted from Curcuma longa L. and an evaluation of their cytotoxic, enzymatic, antioxidant and anti-inflammatory activities
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Hamza_2019_PeerJ_7_e7460Evaluation of the effects of the green nanoparticles zinc oxide on monosodium glutamate-induced toxicity in the brain of rats
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Han_2019_Bioprocess.Biosyst.Eng_42_1739Rational enhancement of enzyme-catalyzed enantioselective reaction by construction of recombinant enzymes based on additive strategy
Han_2019_Chin.J.Nat.Med_17_475Bioactive phenazines from an earwig-associated Streptomyces sp
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Han_2019_Nutrients_11_Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches
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Hashem_2019_J.Infect.Dis_220_1558A Highly Immunogenic, Protective, and Safe Adenovirus-Based Vaccine Expressing Middle East Respiratory Syndrome Coronavirus S1-CD40L Fusion Protein in a Transgenic Human Dipeptidyl Peptidase 4 Mouse Model
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Hatami_2019_Chemosphere_219_981Sub-lethal toxicity of chlorpyrifos alone and in combination with polyethylene glycol to common carp (Cyprinus carpio)
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He_2019_J.Proteomics_200_51Label-free absolute protein quantification with data-independent acquisition
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Hedges_2019_Xenobiotica_49_388Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations
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Herman_2019_Int.J.Mol.Sci_20_Effect of Central Injection of Neostigmine on the Bacterial Endotoxin Induced Suppression of GnRH/LH Secretion in Ewes during the Follicular Phase of the Estrous Cycle
Heroux_2019_Neurobiol.Learn.Mem__107030Cholinergic rescue of neurocognitive insult following third-trimester equivalent alcohol exposure in rats
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Hettiarachchi_2019_Microb.Cell.Fact_18_122Characterization of an acetyl xylan esterase from the marine bacterium Ochrovirga pacifica and its synergism with xylanase on beechwood xylan
Hiesinger_2019_ACS.Med.Chem.Lett_10_899Computer-Aided Selective Optimization of Side Activities of Talinolol
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Hildreth_2019_Curr.Dev.Nutr_3_Soluble Epoxide Hydrolase Inhibitor t-AUCB Promotes Murine Brown Adipogenesis: Role of PPAR Gamma and PPAR Alpha (P21-069-19)
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Hira_2019_Biomolecules_9_beta-Carotene: A Natural Compound Improves Cognitive Impairment and Oxidative Stress in a Mouse Model of Streptozotocin-Induced Alzheimer's Disease
Hiraga_2019_EMBO.Rep_20_e49365Biodegradation of waste PET: A sustainable solution for dealing with plastic pollution
Hitch_2019_PeerJ_7_e7249A proposed update for the classification and description of bacterial lipolytic enzymes
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Hoffmann_2019_J.Med.Chem_62_9116Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer's Disease Mouse Model
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Holck_2019_Enzyme.Microb.Technol_129_109353Novel xylanolytic triple domain enzyme targeted at feruloylated arabinoxylan degradation
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Hong_2019_J.Biotechnol_304_10High-level expression of Humicola insolens cutinase in Pichia pastoris without carbon starvation and its use in cotton fabric bioscouring
Hong_2019_J.Nat.Prod_82_3221Alkaloids from the Branches and Leaves of Elaeocarpus angustifolius
Hope_2019_Front.Genet_10_574The Drosophila Gene Sulfateless Modulates Autism-Like Behaviors
Hopkins_2019_Insect.Biochem.Mol.Biol_106_10The molecular basis for the neofunctionalization of the juvenile hormone esterase duplication in Drosophila
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Hou_2019_Ann.Transl.Med_7_634Galanthamine improves myocardial ischemia-reperfusion-induced cardiac dysfunction, endoplasmic reticulum stress-related apoptosis, and myocardial fibrosis by suppressing AMPK/Nrf2 pathway in rats
Hou_2019_Drug.Alcohol.Depend_202_168Evaluation of the cholinesterase activity of a potential therapeutic cocaine esterase for cocaine overdose
Houze_2019_Toxics_7_Comparison of the Respiratory Toxicity and Total Cholinesterase Activities in Dimethyl Versus Diethyl Paraoxon-Poisoned Rats
Hsu_2019_ACS.Med.Chem.Lett_10_761Synthesis and Molecular Properties of Nerve Agent Reactivator HLo-7 Dimethanesulfonate
Hsueh_2019_Cell.Transplant__963689719854693(-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice
Hu_2019_ACS.Chem.Neurosci_10_537Design, Synthesis, and Biological Evaluation of Dual-Target Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 9A (PDE9A) for the Treatment of Alzheimer's Disease
Hu_2019_Anal.Bioanal.Chem_411_7879Leek-derived codoped carbon dots as efficient fluorescent probes for dichlorvos sensitive detection and cell multicolor imaging
Hu_2019_Anal.Chim.Acta_1085_91Nanoporous gold electrode for ultrasensitive detection of neurotoxin fasciculin
Hu_2019_Biomed.Res.Int_2019_8642784Lipoprotein-Associated Phospholipase A2 Activity and Mass as Independent Risk Factor of Stroke: A Meta-Analysis
Hu_2019_Biosens.Bioelectron_136_112Visual detection of mixed organophosphorous pesticide using QD-AChE aerogel based microfluidic arrays sensor
Hu_2019_Brain.Pathol_29_502Early growth response-1 regulates acetylcholinesterase and its relation with the course of Alzheimer's disease
Hu_2019_Cancers.(Basel)_11_Synergy of Ginkgetin and Resveratrol in Suppressing VEGF-Induced Angiogenesis: A Therapy in Treating Colorectal Cancer
Hu_2019_Chem.Sci_10_1457Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system
Hu_2019_Ecotoxicol.Environ.Saf_171_871Effects of cadmium on fecundity and defence ability of Drosophila melanogaster
Hu_2019_Exp.Ther.Med_18_4388Ginseng berry aqueous extract prevents scopolamine-induced memory impairment in mice
Hu_2019_FASEB.J_33_532Polydatin suppresses VEGF-induced angiogenesis through binding with VEGF and inhibiting its receptor signaling
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Hu_2019_J.Chem.Inf.Model_59_1554MD Simulation Investigation on the Binding Process of Smoke-Derived Germination Stimulants to Its Receptor
Hu_2019_J.Clin.Invest_129_5204Soluble epoxide hydrolase promotes astrocyte survival in retinopathy of prematurity
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Huang_2019_Analyst_144_3436A sensitive fluorescence assay of organophosphorus pesticides using acetylcholinesterase and copper-catalyzed click chemistry
Huang_2019_Bioengineered_10_150Different construction strategies affected on the physiology of Pichia pastoris strains highly expressed lipase by transcriptional analysis of key genes
Huang_2019_Bioorg.Med.Chem_27_644Identification of novel uracil derivatives incorporating benzoic acid moieties as highly potent Dipeptidyl Peptidase-IV inhibitors
Huang_2019_Chem.Biol.Drug.Des_93_110Design, synthesis, and evaluation of genipin derivatives for the treatment of Alzheimer's Disease
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Huang_2019_Front.Microbiol_10_2846New Dihydroisocoumarin Root Growth Inhibitors From the Sponge-Derived Fungus Aspergillus sp. NBUF87
Huang_2019_Int.J.Mol.Sci_20_Polyalthia Clerodane Diterpene Potentiates Hypoglycemia via Inhibition of Dipeptidyl Peptidase 4
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Huang_2019_J.Agric.Food.Chem_67_8548Biodegradation of Structurally Diverse Phthalate Esters by a Newly Identified Esterase with Catalytic Activity toward Di(2-ethylhexyl) Phthalate
Huang_2019_Molecules_24_Two New AChE Inhibitors Isolated from Li Folk Herb Heilaohu Kadsura coccinea Stems
Huang_2019_Oncotarget_10_5419SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells
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Huang_2019_Sci.Rep_9_1379Telencephalon transcriptome analysis of chronically stressed adult zebrafish
Huang_2019_Semin.Arthritis.Rheum_48_745Concurrent inflammatory myopathy and myasthenia gravis with or without thymic pathology: A case series and literature review
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Levy_2019_Antioxidants.(Basel)_8_Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview
Li_2019_ACS.Appl.Mater.Interfaces_11_15718Artificial Nanometalloenzymes for Cooperative Tandem Catalysis
Li_2019_Anal.Methods_11_5203A disposable acetylcholine esterase sensor for As(III) determination in groundwater matrix based on 4-acetoxyphenol hydrolysis
Li_2019_Analyst_144_2034Metal coordination polymer induced perylene probe excimer fluorescence and its application in acetylcholinesterase sensing and alpha-fetoprotein immunoassay
Li_2019_Ann.Thorac.Surg_108_912Results of Robotic Thymectomy Performed in Myasthenia Gravis Patients Older Than 60 Years at Onset
Li_2019_Appl.Biochem.Biotechnol_187_424Identification of a Novel Feruloyl Esterase by Functional Screening of a Soil Metagenomic Library
Li_2019_Bioanalysis_11_2145Fluoride reactivation-enabled sensitive quantification of tabun adducts on human serum albumin by GC-MS/MS via isotope dilution
Li_2019_Biol.Res_52_10Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways
Li_2019_Bioorg.Chem_95_103503Protoilludane-type sesquiterpenoids from Armillaria sp. by co-culture with the endophytic fungus Epicoccumsp. associated with Gastrodia elata
Li_2019_Cancer.Manag.Res_11_931Lipase member H is a downstream molecular target of hypoxia inducible factor-1alpha and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines
Li_2019_Chemosphere_220_811The adverse effect of TCIPP and TCEP on neurodevelopment of zebrafish embryos/larvae
Li_2019_Chemosphere_225_443Biodegradability and biodegradation pathway of di-(2-ethylhexyl) phthalate by Burkholderia pyrrocinia B1213
Li_2019_Chemosphere_234_204Transformation pathway and toxicity assessment of malathion in aqueous solution during UV photolysis and photocatalysis
Li_2019_Drug.Metab.Dispos_47_843Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
Li_2019_Ecotoxicol.Environ.Saf_186_109776Effects of low concentrations of triphenyltin on neurobehavior and the thyroid endocrine system in zebrafish
Li_2019_Environ.Pollut_259_113868Environmental co-exposure to TBT and Cd caused neurotoxicity and thyroid endocrine disruption in zebrafish, a three-generation study in a simulated environment
Li_2019_Enzyme.Microb.Technol_126_41Enhancing thermostability of Yarrowia lipolytica lipase 2 through engineering multiple disulfide bonds and mitigating reduced lipase production associated with disulfide bonds
Li_2019_Eur.J.Neurol_26_1296Clinical analysis of Chinese anti-low-density-lipoprotein-receptor-associated protein 4 antibodies in patients with myasthenia gravis
Li_2019_Eur.J.Pharmacol__172423NLGN3 promotes neuroblastoma cell proliferation and growth through activating PI3K/AKT pathway
Li_2019_Evid.Based.Complement.Alternat.Med_2019_5165029Identification and Analysis of Chemical Constituents and Rat Serum Metabolites in Lycopodium clavatum Using UPLC-Q-TOF/MS Combined with Multiple Data-Processing Approaches
Li_2019_Front.Microbiol_10_1751Pretreatment With Bacillus cereus Preserves Against D-Galactosamine-Induced Liver Injury in a Rat Model
Li_2019_Front.Mol.Neurosci_12_213A Conserved Tyrosine Residue in Slitrk3 Carboxyl-Terminus Is Critical for GABAergic Synapse Development
Li_2019_Gene_704_113A novel ABHD12 nonsense variant in Usher syndrome type 3 family with genotype-phenotype spectrum review
Li_2019_Int.J.Biol.Macromol_121_326Multiple site-directed mutagenesis of a Phaseolus vulgaris epoxide hydrolase to improve its catalytic performance towards p-chlorostyrene oxide based on the computer-aided re-design
Li_2019_Int.J.Biol.Macromol_137_215Effect of organic solvent on enzymatic degradation of cyclic PBS-based polymers by lipase N435
Li_2019_J.Agric.Food.Chem_67_14066Inhibitory Effect of Condensed Tannins from Banana Pulp on Cholesterol Esterase and Mechanisms of Interaction
Li_2019_J.Ethnopharmacol_245_112185Screening of acetylcholinesterase inhibitors and characterizing of phytochemical constituents from Dichocarpum auriculatum (Franch.) W.T. Wang & P. K. Hsiao through UPLC-MS combined with an acetylcholinesterase inhibition assay in vitro
Li_2019_J.Med.Chem_62_2348Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
Li_2019_J.Pharm.Biomed.Anal_168_13Role of esterase mediated hydrolysis of simvastatin in human and rat blood and its impact on pharmacokinetic profiles of simvastatin and its active metabolite in rat
Li_2019_Mol.Catal_476_110517Improving the activity and enantioselectivity of PvEH1, a Phaseolus vulgaris epoxide hydrolase, for o-methylphenyl glycidyl ether by multiple site-directed mutagenesis on the basis of rational design
Li_2019_Molecules_24_2705Bioactive Constituents of F. esculentum Bee Pollen and Quantitative Analysis of Samples Collected from Seven Areas by HPLC
Li_2019_Molecules_24_2980New Sesquiterpenoids from the Fermented Broth of Termitomyces albuminosus and their Anti-Acetylcholinesterase Activity
Li_2019_Molecules_24_489Isolation of Two New Compounds and Other Constituents from Leaves of Piper crocatum and Study of Their Soluble Epoxide Hydrolase Activities
Li_2019_Nat.Biomed.Eng_3_105Genome-edited skin epidermal stem cells protect mice from cocaine-seeking behaviour and cocaine overdose
Li_2019_Nat.Prod.Res__1Wortmannine H, a phenylpentenol isolated from an endophytic fungus, Talaromyces wortmannii LGT-4
Li_2019_Pestic.Biochem.Physiol_160_136Toxicity of Chimonanthus nitens flower extracts to the golden apple snail, Pomacea canaliculata
Li_2019_Prev.Nutr.Food.Sci_24_165Effect of Aged Garlic Ethyl Acetate Extract on Oxidative Stress and Cholinergic Function of Scopolamine-Induced Cognitive Impairment in Mice
Li_2019_Soft.Matter_15_8197Multi-charged bis(p-calixarene)/pillararene functionalized gold nanoparticles for ultra-sensitive sensing of butyrylcholinesterase
Li_2019_Toxicol.In.Vitro_56_93Use of high-throughput enzyme-based assay with xenobiotic metabolic capability to evaluate the inhibition of acetylcholinesterase activity by organophosphorous pesticides
Li_2019_Trends.Plant.Sci_24_669Do Cytokinins and Strigolactones Crosstalk during Drought Adaptation?
Lian_2019_J.Lipid.Res_60_880Ces1d deficiency protects against high-sucrose diet-induced hepatic triacylglycerol accumulation
Liang_2019_ACS.Chem.Neurosci_10_40181-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells
Liang_2019_Biochem.Genet_57_403Identification and Characterization of a Novel Strigolactone-Insensitive Mutant, Dwarfism with High Tillering Ability 34 (dhta-34) in Rice (Oryza sativa L.)
Liang_2019_Biosens.Bioelectron_148_111825Displaying of acetylcholinesterase mutants on surface of yeast for ultra-trace fluorescence detection of organophosphate pesticides with gold nanoclusters
Liang_2019_Neuron_102_843Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay
Liang_2019_Sci.Rep_9_16989Time-Course Changes in Urine Metabolic Profiles of Rats Following 90-Day Exposure to Propoxur
Liao_2019_J.Extracell.Vesicles_8_1628592Acetylcholinesterase is not a generic marker of extracellular vesicles
Liao_2019_J.Med.Food_22_685Aster glehni Extract Ameliorates Scopolamine-Induced Cognitive Impairment in Mice
Liargkova_2019_Molecules_24_Small Multitarget Molecules Incorporating the Enone Moiety
Liebschner_2019_Acta.Crystallogr.D.Struct.Biol_75_861Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Lien_2019_J.Cell.Mol.Med_23_6611The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux
Lima_2019_Mol.Catal_466_75Versatility of Candida antarctica lipase in the amide bond formation applied in organic synthesis and biotechnological processes
Lin_2019_Am.J.Respir.Cell.Mol.Biol_61_162Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia
Lin_2019_Appl.Microbiol.Biotechnol_103_7111Genome sequence of Isaria javanica and comparative genome analysis insights into family S53 peptidase evolution in fungal entomopathogens
Lin_2019_Int.J.Nanomedicine_14_5817Targeted acetylcholinesterase-responsive drug carriers with long duration of drug action and reduced hepatotoxicity
Lin_2019_J.Acute.Med_9_189Successful Resuscitation of a Young Girl Who Drank Rivastigmine With Respiratory Failure
Lin_2019_J.Neurol.Sci_399_144Diffuse Lewy body disease
Lin_2019_PeerJ_7_e6887Galantamine plasma concentration and cognitive response in Alzheimer's disease
Lind_2019_Int.J.Geriatr.Psychiatry_34_1029Antidementia medication use by aged care facility residents with dementia
Ling_2019_Clin.Neurol.Neurosurg_189_105620Distribution characteristics of sweat gland nerve fibres in normal humans identified by acetylcholinesterase histochemical staining
Ling_2019_Molecules_24_Asatone and Isoasatone A Against Spodoptera litura Fab. by Acting on Cytochrome P450 Monoxygenases and Glutathione Transferases
Linna_2019_J.Alzheimers.Dis_71_1297Impact of Anti-Dementia Medication on the Risk of Death and Causes of Death in Alzheimer's Disease
Lisboa_2019_Molecules_25_Toxicity and Antitumor Activity of a Thiophene-Acridine Hybrid
Liu_2019_ACS.Synth.Biol_8_734Designing of a Cofactor Self-Sufficient Whole-Cell Biocatalyst System for Production of 1,2-Amino Alcohols from Epoxides
Liu_2019_Anim.Sci.J_90_271Effects of porcine brain hydrolysate on impairment of cognitive learning ability in amyloid beta(1-40) -infused rats
Liu_2019_Biochem.Biophys.Res.Commun_508_289Structural and functional characterization of polyethylene terephthalate hydrolase from Ideonella sakaiensis
Liu_2019_Bioorg.Chem_90_103101Demethylbellidifolin isolated from Swertia bimaculate against human carboxylesterase 2: Kinetics and interaction mechanism merged with docking simulations
Liu_2019_Chem.Biol.Interact_13ChEPon_306_147Activation of G protein-coupled receptor 30 by flavonoids leads to expression of acetylcholinesterase in cultured PC12cells
Liu_2019_Chem.Commun.(Camb)_55_9797Molecular recognition of organophosphorus compounds in water and inhibition of their toxicity to acetylcholinesterase
Liu_2019_Clin.Chim.Acta_490_142Pediatric reference intervals of liver and renal function tests from birth to adolescence in Chinese children as performed on the Olympus AU5400
Liu_2019_Clin.Microbiol.Infect_25_514 e1Gamma-glutamyl transpeptidase to cholinesterase and platelet ratio in predicting significant liver fibrosis and cirrhosis of chronic hepatitis B
Liu_2019_Curr.Mol.Med_19_364Identifying the Potential Substrates of the Depalmitoylation Enzyme Acyl-protein Thioesterase 1
Liu_2019_Environ.Sci.Pollut.Res.Int_26_24695Single and joint oxidative stress-related toxicity of sediment-associated cadmium and lead on Bellamya aeruginosa
Liu_2019_Fitoterapia__104184New phthalide derivatives from the Biscogniauxia sp. and their activities
Liu_2019_Fitoterapia__104366Anti-cholinesterase activities of constituents isolated from Lycopodiastrum casuarinoides
Liu_2019_Food.Funct_10_432Pharmacodynamic and urinary metabolomics studies on the mechanism of Schisandra polysaccharide in the treatment of Alzheimer's disease
Liu_2019_Food.Funct_10_799The in silico and in vivo evaluation of puerarin against Alzheimer's disease
Liu_2019_Insect.Sci_26_711Exposure to herbicides reduces larval sensitivity to insecticides in Spodoptera litura (Lepidoptera: Noctuidae)
Liu_2019_Int.J.Biol.Macromol_133_1187Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: Kinetics and interaction mechanism merged with simulations
Liu_2019_J.Agric.Food.Chem_67_836Directed Evolution of Sulfonylurea Esterase and Characterization of a Variant with Improved Activity
Liu_2019_J.Anim.Physiol.Anim.Nutr.(Berl)_103_1934Dietary mulberry leaf powder affects growth performance, carcass traits and meat quality in finishing pigs
Liu_2019_J.Atheroscler.Thromb_26_136A Compound Heterozygous Mutation of Lipase Maturation Factor 1 is Responsible for Hypertriglyceridemia of a Patient
Liu_2019_J.Biochem.Mol.Toxicol__e22391ATGL promotes the proliferation of hepatocellular carcinoma cells via the p-AKT signaling pathway
Liu_2019_J.Cancer_10_3746Circulating lncRNA ABHD11-AS1 serves as a biomarker for early pancreatic cancer diagnosis
Liu_2019_J.Chromatogr.A__460454Capillary electrophoresis-immobilized enzyme microreactors for acetylcholinesterase assay with surface modification by highly-homogeneous microporous layer
Liu_2019_J.Sep.Sci_42_1194Large-scale separation of acetylcholinesterase inhibitors from Zanthoxylum nitidum by pH-zone-refining counter-current chromatography target-guided by ultrafiltration high-performance liquid chromatography with ultraviolet and mass spectrometry screening
Liu_2019_Nat.Prod.Res__1New biphenanthrenes with butyrylcholinesterase inhibitory activitiy from Cremastra appendiculata
Liu_2019_Neurosci.Lett__134417Structural and functional abnormalities of motor endplates in rat skeletal model of myofascial trigger spots
Liu_2019_PLoS.One_14_e0224657Three-dimensional (3D) brain microphysiological system for organophosphates and neurochemical agent toxicity screening
Liu_2019_PLoS.One_14_e0226698Comparative transcriptome reveals the potential modulation mechanisms of estradiol affecting ovarian development of female Portunus trituberculatus
Liu_2019_Parkinsonism.Relat.Disord_60_14Pharmacological treatment of apathy in Lewy body disorders: A systematic review
Liu_2019_Phytomedicine__153077Systematic exploration of Astragalus membranaceus and Panax ginseng as immune regulators: Insights from the comparative biological and computational analysis
Liu_2019_Sci.China.Life.Sci_62_609De novo assembly of white poplar genome and genetic diversity of white poplar population in Irtysh River basin in China
Liu_2019_Sci.Total.Environ_666_1106Specific quorum sensing molecules of ammonia oxidizers and their role during ammonium metabolism in Zhalong wetland, China
Liu_2019_Vascul.Pharmacol_120_106544Nox4 and soluble epoxide hydrolase synergistically mediate homocysteine-induced inflammation in vascular smooth muscle cells
Liu_2019_Zhonghua.Yi.Xue.Za.Zhi_99_3221[Distribution characteristics and correlation analysis of antibody detection value in myasthenia gravis]
Liu_2019_iScience_17_144Strigolactones Play an Important Role in Shaping Exodermal Morphology via a KAI2-Dependent Pathway
Lleo_2019_Mol.Cell.Proteomics_18_546Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid
Lockridge_2019_Chem.Biol.Interact__108788Half-life of chlorpyrifos oxon and other organophosphorus esters in aqueous solution
Loesche_2019_Bioorg.Chem_90_103092Novel 12-hydroxydehydroabietylamine derivatives act as potent and selective butyrylcholinesterase inhibitors
Loesche_2019_Molecules_24_Triterpene-Based Carboxamides Act as Good Inhibitors of Butyrylcholinesterase
Lofgren_2019_Chembiochem_20_1438Transesterification of a Tertiary Alcohol by Engineered Candida antarctica Lipase A
Logroscino_2019_Expert.Opin.Pharmacother__1Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs
Lol_2019_Malar.J_18_202Development of molecular assays to detect target-site mechanisms associated with insecticide resistance in malaria vectors from Latin America
Lopes_2019_Ecotoxicol.Environ.Saf_173_494Brain acetylcholinesterase of three perciformes: From the characterization to the in vitro effect of metal ions and pesticides
Lopes_2019_Medchemcomm_10_2089Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling
Lopes_2019_Parasit.Vectors_12_591Insecticide resistance in Culex quinquefasciatus Say, 1823 in Brazil: a review
Lopez-Romero_2019_Channels.(Austin)_13_207TRP ion channels: Proteins with conformational flexibility
Lopez_2019_Molecules_24_Efficacy of Origanum syriacum Essential Oil against the Mosquito Vector Culex quinquefasciatus and the Gastrointestinal Parasite Anisakis simplex, with Insights on Acetylcholinesterase Inhibition
Lordan_2019_Molecules_24_Forty Years Since the Structural Elucidation of Platelet-Activating Factor (PAF): Historical, Current, and Future Research Perspectives
Lores-Arnaiz_2019_Exp.Gerontol_118_88Changes in motor function and brain cortex mitochondrial active oxygen species production in aged mice
Lorke_2019_Front.Neurosci_13_427The Experimental Oxime K027-A Promising Protector From Organophosphate Pesticide Poisoning. A Review Comparing K027, K048, Pralidoxime, and Obidoxime
Lorke_2019_J.Appl.Toxicol_39_101Reversible cholinesterase inhibitors as pretreatment for exposure to organophosphates. A review
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Louhichi_2019_Orphanet.J.Rare.Dis_14_112Thyroid involvement in Chanarin-Dorfman syndrome in adults in the largest series of patients carrying the same founder mutation in ABHD5 gene
Lu_2019_Appl.Microbiol.Biotechnol_103_3421Biochemical profiles of two thermostable and organic solvent-tolerant esterases derived from a compost metagenome
Lu_2019_Bioorg.Chem_85_117Expansion of the scaffold diversity for the development of highly selective butyrylcholinesterase (BChE) inhibitors: Discovery of new hits through the pharmacophore model generation, virtual screening and molecular dynamics simulation
Lu_2019_Int.J.Mol.Sci_20_A Novel Dipeptidyl Peptidase IV Inhibitory Tea Peptide Improves Pancreatic beta-Cell Function and Reduces alpha-Cell Proliferation in Streptozotocin-Induced Diabetic Mice
Lu_2019_Pestic.Biochem.Physiol_160_127Copper exposure enhances Spodoptera litura larval tolerance to beta-cypermethrin
Lu_2019_Pharm.Biol_57_453Epigenetic mechanisms underlying the effects of triptolide and tripchlorolide on the expression of neuroligin-1 in the hippocampus of APP/PS1 transgenic mice
Luc_2019_Life.Sci_231_116483Tackling Alzheimer's disease: Hypothetical synergism between anti-inflammatory and anti-diabetic agents
Lucero_2019_Biomed.Res.Int_2019_7901760Validity and Reliability of an Assessment Tool for the Screening of Neurotoxic Effects in Agricultural Workers in Chile
Luderwald_2019_Sci.Total.Environ_663_518A blessing in disguise? Natural organic matter reduces the UV light-induced toxicity of nanoparticulate titanium dioxide
Lule-Chavez_2019_Neotrop.Entomol_48_706Detrimental Effects of Induced Antibodies on Aedes aegypti Reproduction
Lum_2019_Singapore.Med.J_60_154Medication compliance in Singaporean patients with Alzheimer's disease
Luo_2019_BMC.Neurosci_20_32An enhanced staining method K-B-2R staining for three-dimensional nerve reconstruction
Luo_2019_Bioorg.Med.Chem__115190Synthesis, in vitro and in vivo biological evaluation of novel graveolinine derivatives as potential anti-Alzheimer agents
Luo_2019_Chem.Biol.Interact_13ChEPon_308_164Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on acetylcholinesterase during myogenic differentiation of contractile rat primary skeletal muscle cells
Luo_2019_Front.Pharmacol_10_395Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway
Luo_2019_Langmuir_35_9050Surfactant Charge Modulates Structure and Stability of Lipase-Embedded Monolayers at Marine-Relevant Aerosol Surfaces
Luo_2019_Nat.Prod.Res__1A new diterpenoid alkaloid from Aconitum hemsleyanum
Luo_2019_Neuromuscul.Disord_29_549Novel compound heterozygous GFPT1 mutations in a family with limb-girdle myasthenia with tubular aggregates
Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK
Luque-Martin_2019_Front.Pharmacol_10_1242Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis
Luzeena_2019_Gen.Comp.Endocrinol_279_53Transient exposure of methylparaben to zebrafish (Danio rerio) embryos altered cortisol level, acetylcholinesterase activity and induced anxiety-like behaviour
Lv_2019_BMC.Neurol_19_114Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese population
Lv_2019_Clin.Lab_65_A Case Report of Primary Neonatal Hypocholinesterase Caused by Homozygous Frameshift Mutation of the butyrylcholinesterase (BCHE) Gene and Review of Literature
Lynn_2019_Biosci.Biotechnol.Biochem_83_892(1)H Quantitative NMR analyses of beta-asarone and related compounds for quality control of Acorus rhizome herbal drugs in terms of the effects of their constituents on in vitro acetylcholine esterase activity
Ma_2019_Am.J.Alzheimers.Dis.Other.Demen__1533317519848237Effect of CYP2D6 and CYP3A4 Genotypes on the Efficacy of Cholinesterase Inhibitors in Southern Chinese Patients With Alzheimer's Disease
Ma_2019_Fish.Physiol.Biochem_45_199Identification of Carassius auratus gibelio liver cell proteins interacting with the GABAA receptor gamma2 subunit using a yeast two-hybrid system
Ma_2019_Front.Neurosci_13_1400Neuroprotective Effect of Resveratrol via Activation of Sirt1 Signaling in a Rat Model of Combined Diabetes and Alzheimer's Disease
Ma_2019_Int.J.Biol.Macromol_133_1090Polysaccharide from Spirulina platensis ameliorates diphenoxylate-induced constipation symptoms in mice
Ma_2019_J.Agric.Food.Chem_67_2429Developmental Toxicity of a Neonicotinoid Insecticide, Acetamiprid to Zebrafish Embryos
Ma_2019_J.Food.Sci.Technol_56_835Synthesis of cocoa butter substitutes from Cinnamomum camphora seed oil and fully hydrogenated palm oil by enzymatic interesterification
Ma_2019_Pestic.Biochem.Physiol_157_204Overexpression of multiple cytochrome P450 genes associated with sulfoxaflor resistance in Aphis gossypii Glover
Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation
Maan_2019_Future.Microbiol_14_1397Rv2223c, an acid inducible carboxyl-esterase of Mycobacterium tuberculosis enhanced the growth and survival of Mycobacterium smegmatis
Maayah_2019_J.Cardiovasc.Pharmacol_74_235Role of Cytochrome p450 and Soluble Epoxide Hydrolase Enzymes and Their Associated Metabolites in the Pathogenesis of Diabetic Cardiomyopathy
Macek Hrvat_2019_Toxicol.Lett_321_83Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
Machal_2019_Curr.Vasc.Pharmacol_17_35Efficacy of P2Y12 Receptor Blockers After Myocardial Infarction and Genetic Variability of their Metabolic Pathways
Macht_2019_Brain.Behav.Immun_80_384Pyridostigmine bromide and stress interact to impact immune function, cholinergic neurochemistry and behavior in a rat model of Gulf War Illness
Macierzanka_2019_Adv.Colloid.Interface.Sci_274_102045Bile salts in digestion and transport of lipids
Madav_2019_Brain.Res.Bull_146_171Recent therapeutic strategies targeting beta amyloid and tauopathies in Alzheimer's disease
Maestri_2019_Nat.Chem_11_1082Alkenyl boost for Catellani
Magaletta_2019_FASEB.Bioadv_1_450The Kinesin-3 motor, KLP-4, mediates axonal organization and cholinergic signaling in Caenorhabditis elegans
Magalhaes_2019_Rev.Bras.Enferm_72_32Occupational exposure and poisoning by chemical products in the Federal District
Magnin_2019_ACS.Omega_4_18663Studies Exploring the Interaction of the Organophosphorus Compound Paraoxon with Fullerenes
Magnin_2019_Waste.Manag_85_141Enzymatic recycling of thermoplastic polyurethanes: Synergistic effect of an esterase and an amidase and recovery of building blocks
Mahajan_2019_Int.J.Biol.Macromol_122_806Biodegradation of di-n-butyl phthalate by psychrotolerant Sphingobium yanoikuyae strain P4 and protein structural analysis of carboxylesterase involved in the pathway
Maharajan_2019_J.Biomol.Struct.Dyn__1Discovery of new potential triplet acting inhibitor for Alzheimer disease via X-ray Crystallography, Molecular Docking and Molecular Dynamics
Maharramov_2019_Arch.Pharm.(Weinheim)__e1800317Synthesis, crystal structure, and biological evaluation of optically active 2-amino-4-aryl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-3-carbonitriles: Antiepileptic, antidiabetic, and anticholinergics potentials
Mahdavi_2019_Chem.Biodivers_16_e1800488Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti-Alzheimer's Agents
Mahdavinia_2019_Int.J.Mol.Cell.Med_8_141Protective Effect of Naringin on Bisphenol A-Induced Cognitive Dysfunction and Oxidative Damage in Rats
Mahgoub_2019_Molecules_24_Synthesis, Crystal Structure, and Biological Evaluation of Fused Thiazolo[3,2-a]Pyrimidines as New Acetylcholinesterase Inhibitors
Mahmoud_2019_Environ.Sci.Pollut.Res.Int_26_20731Potential role of N-acetylcysteine on chlorpyrifos-induced neurotoxicity in rats
Mahmoud_2019_Eur.J.Med.Chem_182_111651Neurobehavioral investigation and acetylcholinesterase inhibitory activity study for some new coumarin derivatives
Mahmoudi_2019_Bioelectrochemistry_130_107348High-performance electrochemical enzyme sensor for organophosphate pesticide detection using modified metal-organic framework sensing platforms
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Mahran_2019_J.Chromatogr.A__460371Effect-directed analysis by high-performance thin-layer chromatography for bioactive metabolites tracking in Primula veris flower and Primula boveana leaf extracts
Mahran_2019_J.Chromatogr.A__460438Guided isolation of new iridoid glucosides from Anarrhinum pubescens by high-performance thin-layer chromatography-acetylcholinesterase assay
Majima_2019_J.Nutr.Sci.Vitaminol.(Tokyo)_65_S104Biological Functions of alpha-Tocopheryl Succinate
Makhaeva_2019_Bioorg.Chem_91_103097Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors
Makhaeva_2019_Bioorg.Chem__103387Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation
Makhaeva_2019_Chem.Biol.Interact_13ChEPon_308_224Overview of novel multifunctional agents based on conjugates of gamma-carbolines, carbazoles, tetrahydrocarbazoles, phenothiazines, and aminoadamantanes for treatment of Alzheimer's disease
Makhaeva_2019_Dokl.Biochem.Biophys_484_1Anticholinesterase and Antioxidant Activity of New Binary Conjugates of gamma-Carbolines
Makhaeva_2019_Russ Chem Bull_68_967Cholinesterase and carboxylesterase inhibitors as pharmacological agents
Makino_2019_FEBS.Open.Bio_9_1337Carboxypeptidase Y activity and maintenance is modulated by a large helical structure
Malabaey_2019_Am.J.Case.Rep_20_1418Pyridostigmine Suicidal Attempt in a Myasthenia Gravis Patient
Malegiannaki_2019_Hell.J.Nucl.Med_22 Suppl_123Ageing and Down syndrome: Neurocognitive characteristics and pharmacological treatment
Malek_2019_Curr.Alzheimer.Res_16_815Synthesis and Biological Evaluation of Novel Chromone+Donepezil Hybrids for Alzheimer's Disease Therapy
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Malekshah_2019_J.Control.Release_311-312_273Bioengineered adipose-derived stem cells for targeted enzyme-prodrug therapy of ovarian cancer intraperitoneal metastasis
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Malik_2019_Cureus_11_e6451Correlation Between Donepezil and QTc Prolongation and Torsades de Pointes: A Very Rare Phenomenon
Malomo_2019_J.Food.Biochem_43_e12897Kinetics of acetylcholinesterase inhibition by hemp seed protein-derived peptides
Mamdooh_2019_Drug.Dev.Res_80_310Evaluation of selected commercial pharmacotherapeutic drugs as potential pancreatic lipase inhibitors and antiproliferative compounds
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Mao_2019_Pestic.Biochem.Physiol_156_80The influence of temperature on the toxicity of insecticides to Nilaparvata lugens (Stal)
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Ming_2019_Genomics_111_1034Molecular footprints of inshore aquatic adaptation in Indo-Pacific humpback dolphin (Sousa chinensis)
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Missaglia_2019_Cells_8_Neutral Lipid Storage Diseases as Cellular Model to Study Lipid Droplet Function
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Moverare-Skrtic_2019_FASEB.J__fj201900707ROsteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans
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Munder_2019_Medchemcomm_10_280Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic beta-cells' proliferation and functions
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Parker_2019_Nature_567_187An integrative systems genetic analysis of mammalian lipid metabolism
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Shang_2019_Biochem.Biophys.Res.Commun_519_274Structural and functional analyses of the lipase CinB from Enterobacter asburiae
Shang_2019_Cancer.Res_79_5513Macrophage ABHD5 Suppresses NFkappaB-Dependent Matrix Metalloproteinase Expression and Cancer Metastasis
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Shao_2019_Psychosomatics_60_533Is Lower Plasma Cholinesterase Activity Really a Candidate Biomarker for Postoperative Delirium After Noncardiac Surgery?
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Sharifkhodaei_2019_Development_146_Scribble and Discs Large mediate tricellular junction formation
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Sharma_2019_Toxicol.Rep_6_1164Neuroprotective potential of solanesol in intracerebroventricular propionic acid induced experimental model of autism: Insights from behavioral and biochemical evidence
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Shi_2019_BMB.Rep_52_451High NDRG3 expression facilitates HCC metastasis by promoting nuclear translocation of beta-catenin
Shi_2019_Ecotoxicol.Environ.Saf_179_119Acute exposure to triphenyl phosphate (TPhP) disturbs ocular development and muscular organization in zebrafish larvae
Shi_2019_Genes.(Basel)_10_Determination of Genetic Effects of LIPK and LIPJ Genes on Milk Fatty Acids in Dairy Cattle
Shi_2019_Int.J.Biol.Macromol_136_512Naja atra cardiotoxins enhance the protease activity of chymotrypsin
Shi_2019_Sci.Rep_9_14997A systemic study of indoxacarb resistance in Spodoptera litura revealed complex expression profiles and regulatory mechanism
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Shiau_2019_Sci.Rep_9_11974Mechanism of Interleukin-4 Reducing Lipid Deposit by Regulating Hormone-Sensitive Lipase
Shields_2019_Sci.Rep_9_890Biochemical and Proteomic Characterization of Recombinant Human alpha/beta Hydrolase Domain 6
Shih_2019_Eur.J.Pharmacol__172851Differential blockade by huperzine A and donepezil of sympathetic nicotinic acetylcholine receptor-mediated nitrergic neurogenic dilations in porcine basilar arteries
Shin_2019_Alzheimers.Res.Ther_11_110Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model
Shin_2019_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1864_907Lipid-metabolizing serine hydrolases in the mammalian central nervous system: endocannabinoids and beyond
Shin_2019_Cell.Chem.Biol_26_1036Diacylglycerol Lipase-beta Is Required for TNF-alpha Response but Not CD8(+) T Cell Priming Capacity of Dendritic Cells
Shirayama_2019_Brain.Imaging.Behav_13_75rCBF and cognitive impairment changes assessed by SPECT and ADAS-cog in late-onset Alzheimer's disease after 18 months of treatment with the cholinesterase inhibitors donepezil or galantamine
Shrestha_2019_Molecules_24_Phytochemical Fingerprinting and In Vitro Bioassays of the Ethnomedicinal Fern Tectaria coadunata (J. Smith) C. Christensen from Central Nepal
Shuai_2019_Future.Med.Chem_11_2687Design, synthesis and molecular modeling of isothiochromanone derivatives as acetylcholinesterase inhibitors
Shukla_2019_Physiol.Mol.Biol.Plants_25_1073A proteomic study of cysteine protease induced cell death in anthers of male sterile tobacco transgenic plants
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Siebert_2019_J.Sci.Food.Agric_99_6644Hydrolysis of chlorogenic acid in apple juice using a p-coumaryl esterase of Rhizoctonia solani
Siebert_2019_Nat.Prod.Res__1Determination of acetylcholinesterase and alpha-glucosidase inhibition by electrophoretically-mediated microanalysis and phenolic profile by HPLC-ESI-MS/MS of fruit juices from Brazilian Myrtaceae Plinia cauliflora (Mart.) Kausel and Eugenia uniflora L
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Silva_2019_Environ.Toxicol.Chem_38_412Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level
Silva_2019_PLoS.One_14_e0213393Chemical profile of Lippia thymoides, evaluation of the acetylcholinesterase inhibitory activity of its essential oil, and molecular docking and molecular dynamics simulations
Silva_2019_Sci.Total.Environ_707_134434Behavior and biochemical responses of the polychaeta Hediste diversicolor to polystyrene nanoplastics
Silvia_2019_Environ.Toxicol.Pharmacol_73_103280Evaluation of endocrine disruption and gestational disorders in women residing in areas with intensive pesticide application: An exploratory study
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Simunkova_2019_Arch.Toxicol_93_2491Management of oxidative stress and other pathologies in Alzheimer's disease
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Sinan_2019_Int.J.Environ.Health.Res__1A comparative study of the HPLC-MS profiles and biological efficiency of different solvent leaf extracts of two African plants: Bersama abyssinica and Scoparia dulcis
Sinclair_2019_Alzheimers.Res.Ther_11_80Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to these areas
Sine_2019_Biomarkers__1Serum Cholinesterase biomarker study in farmers - Souss Massa Region-, Morocco: case-control study
Singh_2019_Drug.Dev.Ind.Pharm__1Inorganic clay nanocomposite system for improved cholinesterase inhibition and brain pharmacokinetics of donepezil
Singh_2019_Inorg.Chem_58_9773Metal-Organocatalyst for Detoxification of Phosphorothioate Pesticides: Demonstration of Acetylcholine Esterase Activity
Singh_2019_J.Biomol.Struct.Dyn__1Inhibition of Alzheimer's amyloid-beta42 peptide aggregation by a bi-functional bis-tryptoline triazole: Key insights from molecular dynamics simulations
Singh_2019_Rejuvenation.Res_22_60Rapamycin Confers Neuroprotection Against Aging-Induced Oxidative Stress, Mitochondrial Dysfunction, and Neurodegeneration in Old Rats Through Activation of Autophagy
Singh_2019_Steroids_148_11416,17-N'-(alky/arylsulfonyl)pyrazoline substituted neuroprotective heterosteroids: Synthesis, molecular docking and preclinical efficacy/toxicity studies in rodents
Singhal_2019_Mol.Pharm_16_3460Controlled Iontophoretic Delivery in Vitro and in Vivo of ARN14140-A Multitarget Compound for Alzheimer's Disease
Sinha_2019_J.Ind.Microbiol.Biotechnol_46_1217The complete genomic sequence of Streptomyces spectabilis NRRL-2792 and identification of secondary metabolite biosynthetic gene clusters
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Sivabalakrishnan_2019_Parasit.Vectors_12_13Susceptibility to common insecticides and detoxifying enzyme activities in Anopheles sundaicus (sensu lato) after cessation of indoor residual spraying of insecticides in the Jaffna Peninsula and its surroundings in northern Sri Lanka
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Wang_2019_J.Sep.Sci_42_2500Simultaneous determination of short-chain fatty acids in human feces by HPLC with ultraviolet detection following chemical derivatization and solid-phase extraction segmental elution
Wang_2019_Molecules_24_Insight into the Modification of Phosphatidylcholine with n-3 Polyunsaturated Fatty Acids-Rich Ethyl Esters by Immobilized MAS1 Lipase
Wang_2019_Nat.Plants_5_810Musa balbisiana genome reveals subgenome evolution and functional divergence
Wang_2019_Nat.Prod.Res__1Inducing secondary metabolite production from Daldinia eschscholzii JC-15 by red ginseng medium
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Wang_2019_Polymers.(Basel)_11_Fabrication and Properties of a Bio-Based Biodegradable Thermoplastic Polyurethane Elastomer
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Wang_2019_Virol.Sin_34_59Exosomes Released from Rabies Virus-Infected Cells May be Involved in the Infection Process
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Wong_2019_EXCLI.J_18_764Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells
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Wu_2019_Curr.Top.Med.Chem_19_187Small Molecule Natural Products and Alzheimer's Disease
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Wu_2019_J.Mol.Neurosci_67_364TPPU, a sEH Inhibitor, Attenuates Corticosterone-Induced PC12 Cell Injury by Modulation of BDNF-TrkB Pathway
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Wu_2019_Mar.Biotechnol.(NY)_21_707First Genome-wide Association Analysis for Growth Traits in the Largest Coral Reef-Dwelling Bony Fishes, the Giant Grouper (Epinephelus lanceolatus)
Wu_2019_Neuron_102_621Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways
Wu_2019_Neuropsychiatr.Dis.Treat_15_3167Traditional Chinese Medicine Shenmayizhi Decoction Ameliorates Memory And Cognitive Impairment Induced By Scopolamine Via Preventing Hippocampal Cholinergic Dysfunction In Rats
Wu_2019_Nutrients_11_Hepatoprotective Potential of Partially Hydrolyzed Guar Gum against Acute Alcohol-Induced Liver Injury in Vitro and Vivo
Wu_2019_Small__e1900632Polydopamine-Capped Bimetallic AuPt Hydrogels Enable Robust Biosensor for Organophosphorus Pesticide Detection
Wu_2019_Small__e1903108Oxidase-Like Fe-N-C Single-Atom Nanozymes for the Detection of Acetylcholinesterase Activity
Wu_2019_Talanta_198_8Fluorescence sensor for facile and visual detection of organophosphorus pesticides using AIE fluorogens-SiO2-MnO2 sandwich nanocomposites
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Xie_2019_Phytochemistry_157_200Lotuslactone, a non-canonical strigolactone from Lotus japonicus
Xie_2019_Reprod.Toxicol_83_1Effects of two environmental endocrine disruptors di-n-butyl phthalate (DBP) and mono-n-butyl phthalate (MBP) on human sperm functions in vitro
Xiong_2019_Phytochemistry_162_183Lycofargesiines A-F, further Lycopodium alkaloids from the club moss Huperzia fargesii
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Xu_2019_Front.Cell.Neurosci_13_518Neuroligin 3 Regulates Dendritic Outgrowth by Modulating Akt/mTOR Signaling
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Yan_2019_Molecules_24_Catalytic Hydrolysis Mechanism of Cocaine by Human Carboxylesterase 1: An Orthoester Intermediate Slows Down the Reaction
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Yang_2019_Biosci.Biotechnol.Biochem__1Characterization of a novel thermostable carboxylesterase from thermoalkaliphilic bacterium Bacillus thermocloaceae
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Yang_2019_Chin.J.Integr.Med_25_574Effect and Safety of Huannao Yicong Formula () in Patients with Mild-to-Moderate Alzheimer's Disease: A Randomized, Double-Blinded, Donepezil-Controlled Trial
Yang_2019_Diabetes_68_1178A Unique Role of Carboxylesterase 3 (Ces3) in beta-Adrenergic Signaling-Stimulated Thermogenesis
Yang_2019_Front.Pharmacol_10_44Selection of Reference Genes for Expression Analysis in Chinese Medicinal Herb Huperzia serrata
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Yang_2019_J.Enzyme.Inhib.Med.Chem_34_651Synthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer's disease agents
Yang_2019_J.Gene.Med__e3071Association between the LIPG polymorphisms and serum lipid levels in the Maonan and Han populations
Yang_2019_J.Nat.Prod_82_792Bialternacins A-F, Aromatic Polyketide Dimers from an Endophytic Alternaria sp
Yang_2019_Lipids.Health.Dis_18_10LIPG SNPs, their haplotypes and gene-environment interactions on serum lipid levels
Yang_2019_Mikrochim.Acta_186_585Carbon dots co-doped with nitrogen and chlorine for off-on fluorometric determination of the activity of acetylcholinesterase and for quantification of organophosphate pesticides
Yang_2019_Molecules_24_Pesticide Residues Identification by Optical Spectrum in the Time-Sequence of Enzyme Inhibitors Performed on Microfluidic Paper-Based Analytical Devices (microPADs)
Yang_2019_Nat.Metab_1_560Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes
Yang_2019_Nat.Prod.Res__1Fluevirines E and F, two new alkaloids from Flueggea virosa
Yang_2019_Parasit.Vectors_12_77Target-site mutations (AChE-G119S and kdr) in Guangxi Anopheles sinensis populations along the China-Vietnam border
Yang_2019_Phytochem.Anal_30_26Screening and determination for potential acetylcholinesterase inhibitory constituents from ginseng stem-leaf saponins using ultrafiltration (UF)-LC-ESI-MS(2)
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Yao_2019_Food.Chem_302_125199Insights into the improvement of the enzymatic hydrolysis of bovine bone protein using lipase pretreatment
Yao_2019_Methods.Appl.Fluoresc_7_035006A highly sensitive and low-background fluorescence assay for pesticides residues based on hybridization chain reaction amplification assisted by magnetic separation
Yao_2019_Molecules_24_Mori Ramulus (Chin.Ph.)-the Dried Twigs of Morus alba L./Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract
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Yi_2019_Int.J.Biol.Macromol_133_184A natural inhibitor from Alisma orientale against human carboxylesterase 2: Kinetics, circular dichroism spectroscopic analysis, and docking simulation
Yi_2019_J.Med.Food_22_1208Lactobacillus plantarum CQPC02-Fermented Soybean Milk Improves Loperamide-Induced Constipation in Mice
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Yin_2019_Behav.Pharmacol_30_730Sevoflurane-induced inflammation development: involvement of cholinergic anti-inflammatory pathway
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Yoshioka_2019_Molecules_24_alpha-Glucosidase and Pancreatic Lipase Inhibitory Activities of Diterpenes from Indian Mango Ginger (Curcuma amada Roxb.) and Its Derivatives
Young_2019_Cell.Metab_30_51GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism
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Yu_2019_Fitoterapia_135_99Absolute structure assignment of an iridoid-monoterpenoid indole alkaloid hybrid from Dipsacus asper
Yu_2019_Food.Chem.Toxicol_125_376The effects of pinoresinol on cholinergic dysfunction-induced memory impairments and synaptic plasticity in mice
Yu_2019_Food.Chem_271_445Lipase-catalyzed solvent-free synthesis of erythorbyl laurate in a gas-solid-liquid multiphase system
Yu_2019_Front.Pharmacol_10_268Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin
Yu_2019_Int.Clin.Psychopharmacol_34_312Trends of antidementia drugs use in outpatients with Alzheimer's disease in six major cities of China: 2012-2017
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Yu_2019_J.Atheroscler.Thromb_26_762Serum Triglyceride Lipase Concentrations are Independent Risk Factors for Coronary Artery Disease and In-Stent Restenosis
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Yu_2019_Protein.Expr.Purif_154_98Production of Phosphorylated Ric-8A proteins using protein kinase CK2
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Yuan_2019_BMC.Complement.Altern.Med_19_109Neuroprotective effects of berberine in animal models of Alzheimer's disease: a systematic review of pre-clinical studies
Yuan_2019_BMC.Neurol_19_236Augmentation of peripheral lymphocyte-derived cholinergic activity in patients with acute ischemic stroke
Yuan_2019_Environ.Pollut_250_58Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairment in A549 cells
Yuan_2019_Environ.Sci.Technol_53_14638Bisphenol F-Induced Neurotoxicity toward Zebrafish Embryos
Yuan_2019_J.Chromatogr.A__460506Online acetylcholinesterase inhibition evaluation by high-performance liquid chromatography-mass spectrometry hyphenated with an immobilized enzyme reactor
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Zaarur_2019_Mol.Metab_27_75ATGL-1 mediates the effect of dietary restriction and the insulin/IGF-1 signaling pathway on longevity in C. elegans
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Zakrzewicz_2019_Front.Immunol_10_664SLPI Inhibits ATP-Mediated Maturation of IL-1beta in Human Monocytic Leukocytes: A Novel Function of an Old Player
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Zang_2019_J.Hazard.Mater__121684Carboxylesterase, a de-esterification enzyme, catalyzes the degradation of chlorimuron-ethyl in Rhodococcus erythropolis D310-1
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Zatkova_2019_J.Mol.Neurosci_68_171Activation of the Oxytocin Receptor Modulates the Expression of Synaptic Adhesion Molecules in a Cell-Specific Manner
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Zeng_2019_Cancer.Med_8_7074lncRNA ABHD11-AS1, regulated by the EGFR pathway, contributes to the ovarian cancer tumorigenesis by epigenetically suppressing TIMP2
Zengin_2019_Food.Chem.Toxicol_127_237Multidirectional biological investigation and phytochemical profile of Rubus sanctus and Rubus ibericus
Zengin_2019_Food.Res.Int_123_414New insights into the chemical profiling, cytotoxicity and bioactivity of four Bunium species
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Zhang_2019_ACS.Appl.Mater.Interfaces_11_47311Bio-/Nanoimmobilization Platform Based on Bioinspired Fibrin-Bone@Polydopamine-Shell Adhesive Composites for Biosensing
Zhang_2019_AMB.Express_9_13Synergistic effect of acetyl xylan esterase from Talaromyces leycettanus JCM12802 and xylanase from Neocallimastix patriciarum achieved by introducing carbohydrate-binding module-1
Zhang_2019_Anal.Bioanal.Chem_411_905An ultrasensitive signal-on electrochemiluminescence biosensor based on Au nanoclusters for detecting acetylthiocholine
Zhang_2019_Anal.Chem_91_15866Gold Nanoclusters/Iron Oxyhydroxide Platform for Ultrasensitive Detection of Butyrylcholinesterase
Zhang_2019_Antiviral.Res__104693Safety, efficacy, and pharmacokinetics of pradefovir for the treatment of chronic hepatitis B infection
Zhang_2019_Biochemistry_58_2978Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase
Zhang_2019_Biochemistry_58_3943Structural Basis by Which the N-Terminal Polypeptide Segment of Rhizopus chinensis Lipase Regulates Its Substrate Binding Affinity
Zhang_2019_Bioelectrochemistry_127_163A sensitive amperometric AChE-biosensor for organophosphate pesticides detection based on conjugated polymer and Ag-rGO-NH2 nanocomposite
Zhang_2019_Bioorg.Chem_87_395Design, synthesis and evaluation of chalcone Mannich base derivatives as multifunctional agents for the potential treatment of Alzheimer's disease
Zhang_2019_Biotechnol.Lett_41_1223Purification, identification and characterization of an esterase with high enantioselectivity to (S)-ethyl indoline-2-carboxylate
Zhang_2019_Cancer.Lett_465_36Excipient-free nanodispersion of 7-ethyl-10-hydroxycamptothecin exerts potent therapeutic effects against pancreatic cancer cell lines and patient-derived xenografts
Zhang_2019_Cells_8_395An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis
Zhang_2019_Chemosphere_226_817Bioaccumulation, behavior changes and physiological disruptions with gender-dependent in lizards (Eremias argus) after exposure to glufosinate-ammonium and l-glufosinate-ammonium
Zhang_2019_Ecotoxicol.Environ.Saf_183_109581Transcriptomic analysis of Chlorimuron-ethyl degrading bacterial strain Klebsiella jilinsis 2N3
Zhang_2019_Eur.J.Med.Chem_176_228Multi-target design strategies for the improved treatment of Alzheimer's disease
Zhang_2019_Eur.Rev.Med.Pharmacol.Sci_23_3960The association between the D166E polymorphism of the lipoprotein associated phospholipase A2 and risk of myocardial infarction
Zhang_2019_Evid.Based.Complement.Alternat.Med_2019_2721413A Review of Danshen Combined with Clopidogrel in the Treatment of Coronary Heart Disease
Zhang_2019_Food.Chem_274_305High-level expression of Aspergillus niger lipase in Pichia pastoris: Characterization and gastric digestion in vitro
Zhang_2019_Food.Chem_286_29Interesterification of rice bran wax and palm olein catalyzed by lipase: Crystallization behaviours and characterization
Zhang_2019_Food.Funct_10_7315Hydroxy-alpha-sanshool isolated from Zanthoxylum bungeanum attenuates learning and memory impairments in scopolamine-treated mice
Zhang_2019_Int.J.Biol.Macromol_137_1190Rational design of a Yarrowia lipolytica derived lipase for improved thermostability
Zhang_2019_Int.J.Biol.Macromol_140_358Purification and characterization of a thermoalkaliphilic esterase from Bacillus cereus WZZ006 for enantioselective resolution of indoxacarb intermediate
Zhang_2019_Int.J.Mol.Med_44_2047FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis
Zhang_2019_Int.J.Mol.Sci_20_Whole Genome Sequencing and Analysis of Chlorimuron-Ethyl Degrading Bacteria Klebsiella pneumoniae 2N3
Zhang_2019_J.Am.Chem.Soc_141_14643A Flexible Acetylcholinesterase-Modified Graphene for Chiral Pesticide Sensor
Zhang_2019_J.Control.Release_296_14Reassembly of native components with donepezil to execute dual-missions in Alzheimer's disease therapy
Zhang_2019_J.Econ.Entomol_112_1285Transcript-Level Analysis of Detoxification Gene Mutation-Mediated Chlorpyrifos Resistance in Laodelphax striatellus (Hemiptera: Delphacidae)
Zhang_2019_J.Ethnopharmacol__112097Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs
Zhang_2019_J.Med.Chem_62_3575Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II
Zhang_2019_J.Med.Chem_62_8532Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity
Zhang_2019_J.Pharm.Pharmacol_71_1291Soluble epoxide hydrolase inhibitor, TUPS, attenuates isoproterenol/angiotensin II-induced cardiac hypertrophy through mammalian target of rapamycin-mediated autophagy inhibition
Zhang_2019_Mar.Drugs_17_Polyketides from the Mangrove-Derived Endophytic Fungus Cladosporium cladosporioides
Zhang_2019_Mol.Catal_466_146Kinetic model of the enzymatic Michael addition for synthesis of mitomycin analogs catalyzed by immobilized lipase from T. laibacchii
Zhang_2019_Mol.Microbiol_112_649Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici
Zhang_2019_Molecules_24_Potential Pharmacokinetic Drug(-)Drug Interaction Between Harmine, a Cholinesterase Inhibitor, and Memantine, a Non-Competitive N-Methyl-d-Aspartate Receptor Antagonist
Zhang_2019_Neurotoxicol.Teratol_73_54Screening for neurotoxic potential of 15 flame retardants using freshwater planarians
Zhang_2019_Oxid.Med.Cell.Longev_2019_8636835Studies of the Anti-amnesic Effects and Mechanisms of Single and Combined Use of Donepezil and Ginkgo Ketoester Tablet on Scopolamine-Induced Memory Impairment in Mice
Zhang_2019_Phytochemistry_159_199Cholinesterase inhibitory isoquinoline alkaloids from Corydalis mucronifera
Zhang_2019_Proc.Natl.Acad.Sci.U.S.A_116_13305Compartmentalized biosynthesis of mycophenolic acid
Zhang_2019_Sichuan.Da.Xue.Xue.Bao.Yi.Xue.Ban_50_291[Mycobacterium Tuberculosis Rv3084 Encodes Functional Esterase and Suppresses the Pro-inflammatory Cytokines in vivo]
Zhao_2019_ACS.Catal_9_2916How To Break the Janus Effect of H2O2 in Biocatalysis? Understanding Inactivation Mechanisms To Generate more Robust Enzymes
Zhao_2019_ACS.Chem.Neurosci_10_922Implications of Successful Symptomatic Treatment in Parkinson's Disease for Therapeutic Strategies of Alzheimer's Disease
Zhao_2019_ACS.Omega_4_15234Water-like Dual-Functionalized Ionic Liquids for Enzyme Activation
Zhao_2019_Anal.Cell.Pathol.(Amst)_2019_5901083The Effect of Protein FAM172A on Proliferation in HepG2 Cells and Investigation of the Possible Molecular Mechanism
Zhao_2019_Appl.Microbiol.Biotechnol_103_7129Biodegradation of mycotoxin fumonisin B1 by a novel bacterial consortium SAAS79
Zhao_2019_Arch.Insect.Biochem.Physiol__e21554Molecular and functional properties of two Spodoptera exigua acetylcholinesterase genes
Zhao_2019_Ecotoxicol.Environ.Saf_181_138Accumulation, biodegradation and toxicological effects of N-ethyl perfluorooctane sulfonamidoethanol on the earthworms Eisenia fetida exposed to quartz sands
Zhao_2019_Environ.Int_124_259Urinary biomarkers for assessment of human exposure to monomeric aryl phosphate flame retardants
Zhao_2019_Evid.Based.Complement.Alternat.Med_2019_7365841Treatment Effects of Jinlingzi Powder and Its Extractive Components on Gastric Ulcer Induced by Acetic Acid in Rats
Zhao_2019_Fa.Yi.Xue.Za.Zhi_35_143Time-dependent Expression and Distribution of AChE during the Skin Incised Wound Healing in Mice
Zhao_2019_Front.Cell.Neurosci_13_314Down-Regulation of Essential Synaptic Components by GI-Tract Microbiome-Derived Lipopolysaccharide (LPS) in LPS-Treated Human Neuronal-Glial (HNG) Cells in Primary Culture: Relevance to Alzheimer's Disease (AD)
Zhao_2019_Int.J.Clin.Pharm_41_1414Association between EPHX1 polymorphisms and carbamazepine metabolism in epilepsy: a meta-analysis
Zhao_2019_J.Agric.Food.Chem_67_6940Bioaugmentation of Exogenous Strain Rhodococcus sp. 2G Can Efficiently Mitigate Di(2-ethylhexyl) Phthalate Contamination to Vegetable Cultivation
Zhao_2019_J.Hazard.Mater_384_121358Self-reduction bimetallic nanoparticles on ultrathin MXene nanosheets as functional platform for pesticide sensing
Zhao_2019_J.Pineal.Res__e12630Structural characterisation of melatonin as an inhibitor of the Wnt deacylase Notum
Zhao_2019_Psychosomatics_60_190Low Plasma Cholinesterase Activity is Associated With Postoperative Delirium After Noncardiac Surgery in Elderly Patients: AProspective Observational Study
Zhao_2019_Sci.Total.Environ_700_134492Graphene oxide disrupts the protein-protein interaction between Neuroligin/NLG-1 and DLG-1 or MAGI-1 in nematode Caenorhabditis elegans
Zhao_2019_Toxicol.Sci_171_69Physiologically based kinetic modelling-facilitated reverse dosimetry to predict in vivo red blood cell acetylcholinesterase inhibition following exposure to chlorpyrifos in the Caucasian and Chinese population
Zhao_2019_Xenobiotica__1Reduced systemic exposure and brain uptake of donepezil in rats with scopolamine-induced cognitive impairment
Zheng_2019_Bioorg.Med.Chem__115088Synthesis and biological evaluation of calycanthaceous alkaloid analogs
Zheng_2019_Int.J.Biol.Macromol_125_1016An effective immobilized haloalkane dehalogenase DhaA from Rhodococcus rhodochrous by adsorption, crosslink and PEGylation on meso-cellular foam
Zheng_2019_Protein.Expr.Purif_155_1High-level expression and characterization of a stereoselective lipase from Aspergillus oryzae in Pichia pastoris
Zhou_2019_ACS.Chem.Biol_14_164Activity-Based Protein Profiling Identifies alpha-Ketoamides as Inhibitors for Phospholipase A2 Group XVI
Zhou_2019_Am.J.Transl.Res_11_3056Buyang Huanwu Tang alleviates inflammation and improves motor endplate functions in DSMA rat models by activating several biological molecules and associated signaling pathways
Zhou_2019_Bioorg.Chem_93_103322Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine N-benzylpiperidine fragments
Zhou_2019_Cancer.Manag.Res_11_2139Oncogenic role of ABHD5 in endometrial cancer
Zhou_2019_Chem.Biol.Interact_13ChEPon_308_372Structure-based virtual screening leading to discovery of highly selective butyrylcholinesterase inhibitors with solanaceous alkaloid scaffolds
Zhou_2019_Chem.Sci_10_6341Molecular mechanism of polyketide shortening inanthraquinone biosynthesis of Photorhabdus luminescens
Zhou_2019_Front.Mol.Neurosci_12_304Molecular Architecture of Genetically-Tractable GABA Synapses in C. elegans
Zhou_2019_Front.Pharmacol_10_603Shen-Yuan-Dan Capsule Attenuates Atherosclerosis and Foam Cell Formation by Enhancing Autophagy and Inhibiting the PI3K/Akt/mTORC1 Signaling Pathway
Zhou_2019_J.Colloid.Interface.Sci_546_211Surface functionalization of graphene oxide by amino acids for Thermomyces lanuginosus lipase adsorption
Zhou_2019_J.Proteome.Res_18_1542Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment
Zhou_2019_Molecules_24_Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations
Zhou_2019_Nat.Commun_10_3068Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein
Zhou_2019_Reprod.Toxicol_85_19Redox regulation of hormone sensitive lipase: Potential role in the mechanism of MEHP-induced stimulation of basal steroid synthesis in MA-10 Leydig cells
Zhou_2019_Sci.Rep_9_15564Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences
Zhu_2019_Bioorg.Med.Chem.Lett_29_126625The development of 2-acetylphenol-donepezil hybrids as multifunctional agents for the treatment of Alzheimer's disease
Zhu_2019_Bioorg.Med.Chem.Lett_29_1325Design, synthesis, evaluation and molecular modeling study of 4-N-phenylaminoquinolines for Alzheimer disease treatment
Zhu_2019_Drugs.Aging_36_875Sex Differences in the Prevalent Use of Oral Formulations of Cholinesterase Inhibitors in Older Adults with Dementia
Zhu_2019_Environ.Sci.Technol_53_354Biocatalytic Degradation of Parabens Mediated by Cell Surface Displayed Cutinase
Zhu_2019_Eur.J.Med.Chem_168_330Inhibiting Abeta toxicity in Alzheimer's disease by a pyridine amine derivative
Zhu_2019_Fitoterapia_134_474Lycocasuarines I-Q, new Lycopodium alkaloids isolated from Lycopodiastrum casuarinoides
Zhu_2019_Front.Pharmacol_10_258Jia-Wei-Kai-Xin-San, an Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of Abeta1-42 Induced Cognitive Deficit Mice
Zhu_2019_Int.J.Colorectal.Dis_34_255Optimal time for single-stage pull-through colectomy in infants with short-segment Hirschsprung disease
Zhu_2019_Int.J.Mol.Sci_20_Predicting the Toxicity of Ionic Liquids toward Acetylcholinesterase Enzymes Using Novel QSAR Models
Zhu_2019_J.Agric.Food.Chem_67_10534Structural Features and Digestive Behavior of Fucosylated Chondroitin Sulfate from Sea Cucumbers Stichopus japonicus
Zhu_2019_J.Integr.Neurosci_18_327Current anti-Alzheimer's disease effect of natural products and their principal targets
Zhu_2019_Sci.Total.Environ_668_1117Variation in metabolism and degradation of di-n-butyl phthalate (DBP) by high- and low-DBP accumulating cultivars of rice (Oryza sativa L.) and crude enzyme extracts
Zhuang_2019_Cell.Death.Dis_10_620Long noncoding RNA ABHD11-AS1 functions as a competing endogenous RNA to regulate papillary thyroid cancer progression by miR-199a-5p/SLC1A5 axis
Ziemba-Davis_2019_J.Arthroplasty_34_S343Identifiable Risk Factors to Minimize Postoperative Urinary Retention in Modern Outpatient Rapid Recovery Total Joint Arthroplasty
Zindler_2019_Ecotoxicol.Environ.Saf_186_109754Analysis of tail coiling activity of zebrafish (Danio rerio) embryos allows for the differentiation of neurotoxicants with different modes of action
Zivkovic_2019_Mediators.Inflamm_2019_9258509Response to: Comment on A Sustained Reduction in Serum Cholinesterase Enzyme Activity Predicts Patient Outcome following Sepsis
Zivkovic_2019_Sci.Rep_9_10437Bedside-measurement of serum cholinesterase activity predicts patient morbidity and length of the intensive care unit stay following major traumatic injury
Zong_2019_Microb.Cell.Fact_18_202Substantially improving the enantioconvergence of PvEH1, a Phaseolus vulgaris epoxide hydrolase, towards m-chlorostyrene oxide by laboratory evolution
Zorbaz_2019_Chem.Biol.Interact_13ChEPon_307_16Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes
Zou_2019_Anal.Bioanal.Chem_411_2905Monocrotophos detection with a bienzyme biosensor based on ionic-liquid-modified carbon nanotubes
Zou_2019_Fitoterapia__104186New amide alkaloids from Delphinium brunonianum
Zou_2019_Nat.Commun_10_436The genome of broomcorn millet
Zoubkova_2019_Front.Neurosci_13_771Prenatal Exposure to Methamphetamine: Up-Regulation of Brain Receptor Genes
Zueva_2019_Neuropharmacol_155_131New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease
Zurita_2019_Ecotoxicol.Environ.Saf_176_309Integration of fish cell cultures in the toxicological assessment of effluents
d'Andrea_2019_Cell.Chem.Biol_26_878Late-Stage Conversion of Diphenylphosphonate to Fluorophosphonate Probes for the Investigation of Serine Hydrolases
da Costa_2019_Pharmaceuticals.(Basel)_12_Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos
da Fonseca_2019_Environ.Pollut_252_1180Effects of mixtures of anticancer drugs in the benthic polychaete Nereis diversicolor
da Luz Abreu_2019_Nutr.Metab.(Lond)_16_61(3Z)-5-Chloro-3-(Hydroxyimino)indolin-2-one attenuates hyperglycemia, increased hepatic glycogen content and hepatic damage induced by malathion acute exposure in rats
da Rocha_2019_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_218_30Neurotoxicity in zebrafish exposed to carbon nanotubes: Effects on neurotransmitters levels and antioxidant system
da Rosa_2019_Microb.Pathog__103787Impacts of Escherichia coli infection in young breeder chicks on the behavior and cerebral activity of purinergic and cholinergic enzymes involved in the regulation of molecules with neurotransmitter and neuromodulator function
da Silva Toscano Saes _2019_Bull.Environ.Contam.Toxicol_102_310Sub-lethal Responses of the Polychaete Armandia agilis in Whole-sediment Toxicity Testing
da Silva_2019_3.Biotech_9_38Biocatalytic esterification of fatty acids using a low-cost fermented solid from solid-state fermentation with Yarrowia lipolytica
da Silva_2019_Chem.Biol.Interact_13ChEPon_307_195Molecular modelling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime with VX-inhibited human acetylcholinesterase. A near attack approach to assess different spacer-lengths
da Silva_2019_J.Enzyme.Inhib.Med.Chem_34_1018Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approach
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