2021

Xu_2021_Microb.Cell.Fact_20_152 The N-terminus of Lactobacillus amylovorus feruloyl esterase plays an important role in its secretion by Lactobacillus plantarum and Escherichia coli
Pedroza-Gomez_2021_Pathogens_10_1454 Transcriptome-Based Identification of a Functional Fasciola hepatica Carboxylesterase B
Kealey_2021_Metab.Eng.Commun_13_e00172 Identification of a lichen depside polyketide synthase gene by heterologous expression in Saccharomyces cerevisiae
Xu_2021_All.Life_14_622 Cloning, characterization of a novel acetyl xylan esterase, and its potential application on wheat straw utilization
Kmezik_2021_Sci.Rep_11_17662 Characterization of a novel multidomain CE15-GH8 enzyme encoded by a polysaccharide utilization locus in the human gut bacterium Bacteroides eggerthii
Mafa_2021_AMB.Express_11_21 Feruloyl esterase (FAE-1) sourced from a termite hindgut and GH10 xylanases synergy improves degradation of arabinoxylan
Lim_2021_Int.J.Biol.Macromol_186_414 Identification of regions affecting enzyme activity, substrate binding, dimer stabilization and polyhydroxyalkanoate (PHA) granule morphology in the PHA synthase of Aquitalea sp. USM4
Wang_2021_Front.Plant.Sci_12_664470 Genome-Wide Identification of Tannase Genes and Their Function of Wound Response and Astringent Substances Accumulation in Juglandaceae
Dou_2021_Org.Lett__ Kinetic Resolution of Nearly Symmetric 3-Cyclohexene-1-carboxylate Esters Using a Bacterial Carboxylesterase Identified by Genome Mining
Matabaro_2021_Methods.Enzymol_656_429 Enzyme-mediated backbone N-methylation in ribosomally encoded peptides
Matabaro_2021_Sci.Rep_11_3541 Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A
Onguka_2021_Cell.Chem.Biol__ Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host
Soulenthone_2021_Polym.Degrad.Stab_184_109481 Characterization of a poly(butylene adipate- co -terephthalate) hydrolase from the mesophilic actinobacteria Rhodococcus fascians
Lei_2021_Microb.Cell.Fact_20_197 Degradation of epigallocatechin and epicatechin gallates by a novel tannase Tan(Hcw) from Herbaspirillum camelliae
Magalhaes_2021_Int.J.Mol.Sci_22_11257 Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET
Wang_2021_Int.J.Mol.Sci_22_13366 Systematic Analysis and Biochemical Characterization of the Caffeoyl Shikimate Esterase Gene Family in Poplar
Elhachimi_2021_Ticks.Tick.Borne.Dis_13_101883 Variation of diazinon and amitraz susceptibility of Hyalomma marginatum (Acari: Ixodidae) in the Rabat-Sale-Kenitra region of Morocco
de Saint Germain_2021_Plant.Commun_2_100166 A Phelipanche ramosa KAI2 protein perceives strigolactones and isothiocyanates enzymatically
Lund_2021_Molecules_26_7155 ThermoSlope: A Software for Determining Thermodynamic Parameters from Single Steady-State Experiments
Kawai_2021_Angew.Chem.Int.Ed.Engl_60_10319 Complete Biosynthetic Pathway of Alazopeptin, a Tripeptide Consisting of Two Molecules of 6-Diazo-5-oxo-l-norleucine and One Molecule of Alanine
Meng_2021_Plant.J__ KARRIKIN INSENSITIVE2 regulates leaf development, root system architecture and arbuscular-mycorrhizal symbiosis in Brachypodium distachyon
Guan_2021_Front.Bioeng.Biotechnol_9_806788 Biochemical and Structural Characterization of a Novel Bacterial Tannase From Lachnospiraceae bacterium in Ruminant Gastrointestinal Tract
Vingiani_2021_Sci.Total.Environ_812_152535 First identification and characterization of detoxifying plastic-degrading DBP hydrolases in the marine diatom Cylindrotheca closterium
Kim_2021_Angew.Chem.Int.Ed.Engl_60_19766 Unprecedented Noncanonical Features of the Nonlinear Nonribosomal Peptide Synthetase Assembly Line for WS9326A Biosynthesis
Blazquez-Sanchez_2021_Appl.Environ.Microbiol__AEM0184221 Antarctic polyester hydrolases degrade aliphatic and aromatic polyesters at moderate temperatures
Zhang_2021_ResearchSquare__ The abundance of mRNA transcripts of bacteroidetal polyethylene terephthalate (PET) esterase genes may indicate a role in marine plastic degradation
Zhang_2022_Front.Microbiol_12_803896 The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity
Mazur_2021_Int.J.Mol.Sci_22_11992 Structural Analysis of the Ancestral Haloalkane Dehalogenase AncLinB-DmbA
Ding_2021_Chemosphere_289_133130 Biodegradation of lambda-cyhalothrin through cell surface display of bacterial carboxylesterase
Vazquez-Alcantara_2021_Microbiol.Spectr_9_e0097621 Expression of a Cutinase of Moniliophthora roreri with Polyester and PET-Plastic Residues Degradation Activity
Vasina_2021_ResearchSquare__ Functional and Mechanistic Characterization of an Enzyme Family Combining Bioinformatics and High-Throughput Microfluidics
Schwarz_2021_Biomolecules_11_ Revisiting Jatropha curcas Monomeric Esterase: A Dienelactone Hydrolase Compatible with the Electrostatic Catapult Model
Wang_2021_Acta.Crystallogr.D.Struct.Biol_77_1554 Structural and biochemical analyses of the tetrameric carboxypeptidase S9Cfn from Fusobacterium nucleatum
Novy_2021_J.Biol.Chem__101302 Phylogenetic analysis and in-depth characterization of functionally and structurally diverse CE5 cutinases
Liu_2021_Biomolecules_11_1552 Identification and Biochemical Characterization of a Novel Hormone-Sensitive Lipase Family Esterase Est19 from the Antarctic Bacterium Pseudomonas sp. E2-15
Wang_2021_Pest.Manag.Sci__2 Neuroligin 3 from common cutworm enhances the Gaba-induced current of recombinant Slrdl1 channel
Yao_2021_Czech.J.Genet.Plant.Breed__ Isolation, sequencing of the HvnHID gene and its role in the purple-grain colour development in Tibetan hulless barley
Hu_2021_New.Phytol__ Phytophthora infestans Ago1-associated miRNA promotes potato late blight disease
Ding_2021_Pest.Manag.Sci__ Characterization of the insecticide detoxification carboxylesterase Boest1 from Bradysia odoriphaga Yang et Zhang (Diptera:Sciaridae)
Ding_2021_Pestic.Biochem.Physiol_174_104807 Characterization and functional analysis of two acetylcholinesterase genes in Bradysia odoriphaga Yang et Zhang (Diptera: Sciaridae)
Thaker_2021_Curr.Genet__ Feruloyl esterase Fae1 is required specifically for host colonisation by the rice-blast fungus Magnaporthe oryzae
Lee_2021_Int.J.Biol.Macromol_190_441 Mining of a novel esterase (est3S) gene from a cow rumen metagenomic library with organosphosphorus insecticides degrading capability: Catalytic insights by site directed mutations, docking, and molecular dynamic simulations
Park_2021_Microorganisms_9_ Molecular Characterization of Novel Family IV and VIII Esterases from a Compost Metagenomic Library
Ng_2021_Int.J.Mol.Sci_22_10339 A Novel Lipase from Lasiodiplodia theobromae Efficiently Hydrolyses C8-C10 Methyl Esters for the Preparation of Medium-Chain Triglycerides' Precursors
Yu_2021_ACS.Catalysis_11_11733 Functional Characterization and Crystal Structure of the Bifunctional Thioesterase Catalyzing Epimerization and Cyclization in Skyllamycin Biosynthesis
Liu_2021_Front.Bioeng.Biotechnol_9_697677 Enhanced Production of (S)-2-arylpropionic Acids by Protein Engineering and Whole-Cell Catalysis
Nakamura_2021_ACS.Catal_11_8550 Positive Charge Introduction on the Surface of Thermostabilized PET Hydrolase Facilitates PET Binding and Degradation
Sagong_2021_J.Hazard.Mater_416_126075 Implications for the PET decomposition mechanism through similarity and dissimilarity between PETases from Rhizobacter gummiphilus and Ideonella sakaiensis
Sander_2021_Front.Microbiol_12_672727 Metaproteomic Discovery and Characterization of a Novel Lipolytic Enzyme From an Indian Hot Spring
Xue_2021_Theor.Appl.Genet__ A methyl esterase 1 (PvMES1) promotes the salicylic acid pathway and enhances Fusarium wilt resistance in common beans
Duan_2021_Foods_10_ Characterization of Feruloyl Esterase from Bacillus pumilus SK52.001 and Its Application in Ferulic Acid Production from De-Starched Wheat Bran
Noby_2021_Biorxiv__ Structure and dynamics of a cold-active esterase reveals water entropy and active site accessibility as the likely drivers for cold-adaptation
Noby_2021_Biorxiv_2_ Structure guided engineering of a cold active esterase expands substrate range though a stabilisation mutation that allows access to a buried water chamber
Noby_2021_Open.Biol_11_210182 Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism
Li_2021_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110630 Identification, characterization and mRNA transcript abundance profiles of the carboxylesterase (CXE5) gene in Eriocheir sinensis suggest that it may play a role in methyl farnesoate degradation
Yan_2021_Arch.Microbiol__ Identification and characterization of a novel carboxylesterase EstQ7 from a soil metagenomic library
Chen_2021_Nat.Catal_4_425 General features to enhance enzymatic activity of poly(ethylene terephthalate) hydrolysis
Pavarina_2021_Sci.Rep_11_10440 Characterization of a new bifunctional endo-1,4-beta-xylanase\/esterase found in the rumen metagenome
Wei_2021_J.Agric.Food.Chem__ The alpha-Helical Cap Domain of a Novel Esterase from Gut Alistipes shahii Shaping the Substrate-Binding Pocket
Ohta_2021_Environ.Microbiol__ Degradation of ester linkages in rice straw components by Sphingobium species recovered from the sea bottom using a non-secretory tannase-family alpha\/beta hydrolase
Adina_2021_J.Genet.Eng.Biotechnol_19_55 Expression of novel acidic lipase from Micrococcus luteus in Pichia pastoris and its application in transesterification
Xing_2021_Front.Microbiol_12_633489 Gene Expression, Biochemical Characterization of a sn-1, 3 Extracellular Lipase From Aspergillus niger GZUF36 and Its Model-Structure Analysis
Jiang_2021_Appl.Environ.Microbiol__ Identification of Detoxification Esterase StrH Initiating Strobilurin Fungicides Degradation in Hyphomicrobium sp. DY-1
Jeon_2021_Crystals_11_170 Purification and Crystallographic Analysis of a Novel Cold-Active Esterase (HaEst1) from Halocynthiibacter arcticus
Mohd Din_2021_Catalysts_11_244 Heterologous Expression and Characterization of Plant Lipase LIP2 from Elaeis guineensis Jacq. Oil Palm Mesocarp in Escherichia coli
Mazur_2021_Acta.Crystallogr.D.Struct.Biol_77_347 The tetrameric structure of the novel haloalkane dehalogenase DpaA from Paraglaciecola agarilytica NO2
Dong_2021_Int.J.Mol.Sci_22_ The Cutinase Bdo_10846 Play an Important Role in the Virulence of Botryosphaeria dothidea and in Inducing the Wart Symptom on Apple Plant
Kmezik_2021_J.Biol.Chem__100500 A polysaccharide utilization locus from the gut bacterium Dysgonomonas mossii encodes functionally distinct carbohydrate esterases
Tan_2021_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110590 Molecular cloning and characterization of an atypical butyrylcholinesterase-like protein in zebrafish
Yao_2021_AMB.Express_11_38 A novel esterase from a soil metagenomic library displaying a broad substrate range
Krska_2021_Biochemistry__ Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii
Miguel-Ruano_2021_Comput.Struct.Biotechnol.J_19_1214 Biochemical and Structural Characterization of a novel thermophilic esterase EstD11 provide catalytic insights for the HSL family
Zhang_2021_Chemistry_10_3106 Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans
Pereira_2021_Nat.Commun_12_459 Degradation of complex arabinoxylans by human colonic Bacteroidetes
Tan_2021_Comput.Struct.Biotechnol.J_19_869 An extracellular lipase from Amycolatopsis mediterannei is a cutinase with plastic degrading activity
Wang_2021_Pest.Manag.Sci__ Two carboxylesterase genes in Plutella xylostella associated with sex pheromones and plant volatiles degradation
Dong_2021_Acta.Crystallogr.D.Struct.Biol_77_267 Crystal structure of fungal tannase from Aspergillus niger
Gao_2021_J.Am.Chem.Soc_143_80 A Polyketide Cyclase That Forms Medium-Ring Lactones
Hameleers_2021_Biotechnol.Biofuels_14_127 Polysaccharide utilization loci-driven enzyme discovery reveals BD-FAE: a bifunctional feruloyl and acetyl xylan esterase active on complex natural xylans
Lu_2021_Genes.(Basel)_12_E122 A Novel Carboxylesterase Derived from a Compost Metagenome Exhibiting High Stability and Activity towards High Salinity
Gu_2021_Int.J.Biol.Macromol_171_382 Characteristics of a recombinant Fusarium verticillioides cutinase and its effects on enzymatic hydrolysis of rice straw
Zhao_2021_Proteins__ Mycobacterium tuberculosis puromycin hydrolase displays a prolyl oligopeptidase fold and an acyl aminopeptidase activity
Xi_2021_Enzyme.Microb.Technol_143_109715 Secretory expression in Bacillus subtilis and biochemical characterization of a highly thermostable polyethylene terephthalate hydrolase from bacterium HR29
Hoppner_2021_FEBS.J_288_3570 Crystal structures of a novel family IV esterase in free and substrate-bound form
Shin_2021_Int.J.Biol.Macromol_168_403 Biochemical characterization and molecular docking analysis of novel esterases from Sphingobium chungbukense DJ77
Boyko_2021_Biomolecules_11_ Structural and Biochemical Characterization of a Cold-Active PMGL3 Esterase with Unusual Oligomeric Structure
You_2021_FEBS.J_288_5768 Structural basis for substrate specificity of the peroxisomal acyl-CoA hydrolase MpaH' involved in mycophenolic acid biosynthesis
Yasutake_2021_Int.J.Biol.Macromol_167_578 Bacterial triacylglycerol lipase is a potential cholesterol esterase: Identification of a key determinant for sterol-binding specificity
Lu_2021_Vet.Res_52_3 Protection studies of an excretory-secretory protein HcABHD against Haemonchus contortus infection
Zhao_2021_World.J.Microbiol.Biotechnol_37_212 Characterization and genomic analysis of an efficient dibutyl phthalate degrading bacterium Microbacterium sp. USTB-Y
Vinces_2021_Biorxiv__ Molecular and functional basis of a novel Amazonian Dark Earth Esterase 1 (Ade1) with hysteresis behavior and quorum-quenching activity
Labar_2021_Biomolecules_11_533 Structure and Dynamics of an Archeal Monoglyceride Lipase from Palaeococcus ferrophilus as Revealed by Crystallography and In Silico Analysis
Goryainova_2021_Crystallogr.Rep_66_811 Three-Dimensional Structure of Single-Point Mutant of Esterase PMGL2
Zhu_2021_J.Agric.Food.Chem__ Structural Insights into a Novel Esterase from the East Pacific Rise and Its Improved Thermostability by a Semirational Design
Wang_2021_Plant.Physiol_185_1411 Molecular basis for high ligand sensitivity and selectivity of strigolactone receptors in Striga
Cea-Rama_2021_Comput.Struct.Biotechnol.J_19_2307 Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase
Guan_2021_Insect.Sci_28_627 Whole-genome sequencing to detect mutations associated with resistance to insecticides and Bt proteins in Spodoptera frugiperda
Li_2021_Adv.Synth.Catal_362_4699 Reprogramming Epoxide Hydrolase to Improve Enantioconvergence in Hydrolysis of Styrene Oxide Scaffolds
Graf_2021_Methods.Enzymol_648_337 Structural analysis of PET-degrading enzymes PETase and MHETase from Ideonella sakaiensis
Pinto_2021_ACS.Catal_11_10416 Reaction Mechanism of MHETase, a PET Degrading Enzyme
Hachisuka_2021_Appl.Environ.Microbiol__AEM0002021 Development of a targeted gene disruption system in the PET-degrading bacterium Ideonella sakaiensis and its applications to PETase and MHETase genes
Kan_2021_Chembiochem__ IsPETase represents a novel biocatalyst for poly (ethylene terephthalate) (PET) hydrolysis
Werner_2021_Metab.Eng_67_250 Tandem chemical deconstruction and biological upcycling of poly(ethylene terephthalate) to beta-ketoadipic acid by Pseudomonas putida KT2440
Yoshida_2021_Methods.Enzymol_648_187 Ideonella sakaiensis, PETase, and MHETase: From identification of microbial PET degradation to enzyme characterization
Meyer-Cifuentes_2021_Front.Microbiol_12_693985 Mle046 Is a Marine Mesophilic MHETase-Like Enzyme
Bell_2021_ChemRxiv__ Directed Evolution of an Efficient and Thermostable PET Depolymerase
Cui_2021_ACS.Catal_11_1340 Computational redesign of a PETase for plastic biodegradation under ambient condition by the GRAPE strategy
Jerves_2021_ACS.Catal_11_11626 Reaction Mechanism of the PET Degrading Enzyme PETase Studied with DFT\/MM Molecular Dynamics Simulations
Pirillo_2021_Int.J.Mol.Sci_23_ An Efficient Protein Evolution Workflow for the Improvement of Bacterial PET Hydrolyzing Enzymes
Lu_2021_Biorxiv__ Deep learning redesign of PETase for practical PET degrading applications
Badino_2021_Enzyme.Microb.Technol_152_109937 Adsorption of enzymes with hydrolytic activity on polyethylene terephthalate
Heyde_2021_Microb.Cell.Fact_20_93 Surface display as a functional screening platform for detecting enzymes active on PET
Boneta_2021_J.Chem.Inf.Model__ QM\/MM Study of the Enzymatic Biodegradation Mechanism of Polyethylene Terephthalate
da Costa_2021_Proteins__ Assessment of the PETase conformational changes induced by poly(ethylene terephthalate) binding
Chen_2021_Methods.Enzymol_648_457 Yeast cell surface display of bacterial PET hydrolase as a sustainable biocatalyst for the degradation of polyethylene terephthalate
Dai_2021_J.Biotechnol_334_47 Enhancing PET hydrolytic enzyme activity by fusion of the cellulose-binding domain of cellobiohydrolase I from Trichoderma reesei
Meng_2021_Int.J.Biol.Macromol_180_667 Protein engineering of stable IsPETase for PET plastic degradation by Premuse
Puspitasari_2021_Int.J.Biol.Macromol_176_157 Class I hydrophobins pretreatment stimulates PETase for monomers recycling of waste PETs
Shi_2021_J.Agric.Food.Chem_69_2245 Enhanced Extracellular Production of IsPETase in Escherichia coli via Engineering of the pelB Signal Peptide
Sun_2021_Methods.Enzymol_648_207 GRAPE, a greedy accumulated strategy for computational protein engineering
Zhong-Johnson_2021_Sci.Rep_11_928 An absorbance method for analysis of enzymatic degradation kinetics of poly(ethylene terephthalate) films
Timofeev_2021_Crystals_11_1438 The Crystal Structure of Nalpha-p-tosyl-lysyl Chloromethylketone-Bound Oligopeptidase B from Serratia Proteamaculans Revealed a New Type of Inhibitor Binding.
Petrenko_2021_Biology.(Basel)_10_1021 First Crystal Structure of Bacterial Oligopeptidase B in an Intermediate State: The Roles of the Hinge Region Modification and Spermine
Inak_2021_Pest.Manag.Sci__ Population structure and insecticide resistance status of Tuta absoluta populations from Turkey
Liu_2021_Catal.Sci.Technol__ Reshaping the active pocket of esterase Est816 for resolution of economically important racemates
Bzdrenga_2021_Molecules_26_657 A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study
Ahmad_2021_Curr.Opin.Infect.Dis_34_187 Bacterial RTX toxins and host immunity
Tschesche_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_248_109095 Genomic analysis of the carboxylesterase family in the salmon louse (Lepeophtheirus salmonis)
Mangiagalli_2021_Int.J.Biol.Macromol_181_263 The activity and stability of a cold-active acylaminoacyl peptidase rely on its dimerization by domain swapping
Kaabel_2021_Proc.Natl.Acad.Sci.U.S.A_118_ Enzymatic depolymerization of highly crystalline polyethylene terephthalate enabled in moist-solid reaction mixtures
de Queiros Eugenio_2021_J.Biotechnol__ Experimental and mathematical modeling approaches for biocatalytic post-consumer poly(ethylene terephthalate) hydrolysis
Kawai_2021_Catalysts_11_206 The Current State of Research on PET Hydrolyzing Enzymes Available for Biorecycling
Xue_2021_Front.Bioeng.Biotechnol_9_762854 Fusion of Chitin-Binding Domain From Chitinolyticbacter meiyuanensis SYBC-H1 to the Leaf-Branch Compost Cutinase for Enhanced PET Hydrolysis
Zheng_2021_J.Hazard.Mater_423_127017 Computational biotransformation of polyethylene terephthalate by depolymerase: A QM\/MM approach
Cui_2021_Food.Chem_366_130523 A novel sn-1,3 specific lipase from Janibacter sp. as catalysts for the high-yield synthesis of long-medium-long type structured triacylglycerols
Farooq_2021_Curr.Genet__ Molecular characterization of lipase from a psychrotrophic bacterium Pseudomonas sp. CRBC14
Liu_2021_Plant.Cell__ An ABHD17-like hydrolase screening system to identify de-S-acylation enzymes of protein substrates in plant cells
Sun_2021_Nat.Commun_12_3335 Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity
Roesler_2021_Front.Plant.Sci_12_639401 Arabidopsis Carboxylesterase 20 Binds Strigolactone and Increases Branches and Tillers When Ectopically Expressed in Arabidopsis and Maize
Yao_2021_New.Phytol__ Desmethyl butenolides are optimal ligands for karrikin receptor proteins
Arellano-Saab_2021_Proc.Natl.Acad.Sci.U.S.A_118_ Three mutations repurpose a plant karrikin receptor to a strigolactone receptor
Xu_2021_Nat.Plants_7_1495 Catabolism of strigolactones by a carboxylesterase
Gawarecka_2021_Plant.Cell.Environ__ cis-Prenyltransferase 3 and alpha\/beta-hydrolase are new determinants of dolichol accumulation in Arabidopsis
Jang_2021_Int.J.Mol.Sci_22_ CRISPR-Knockout of CSE Gene Improves Saccharification Efficiency by Reducing Lignin Content in Hybrid Poplar
Rao_2021_Appl.Biochem.Biotechnol_193_560 Immobilized Arabidopsis thaliana Hydroxynitrile Lyase-Catalyzed Retro-Henry Reaction in the Synthesis of (S)-beta-Nitroalcohols
Muller_2021_Biotechnol.Lett_43_287 Synthesis of (R)-mandelic acid and (R)-mandelic acid amide by recombinant E. coli strains expressing a (R)-specific oxynitrilase and an arylacetonitrilase
Villaecija-Aguilar_2021_Curr.Biol__ KAI2 promotes Arabidopsis root hair elongation at low external phosphate by controlling local accumulation of AUX1 and PIN2
Arranz San Martin_2022_Biomolecules_12_170 Enzyme-Mediated Quenching of the Pseudomonas Quinolone Signal (PQS): A Comparison between Naturally Occurring and Engineered PQS-Cleaving Dioxygenases
Kato_2021_J.Biosci.Bioeng__ Identification and characterization of an acetyl xylan esterase from Aspergillus oryzae
Sesham_2021_Bioinformation_17_132 Molecular modeling, docking and dynamics analysis of lipid droplet associated enzyme Ypr147cp from Saccharomyces cerevisiae
Wen_2021_Enzyme.Microb.Technol_146_109778 Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide
Hu_2021_Int.J.Biol.Macromol_169_1 Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity
Silveira_2021_J.Phys.Chem.B__ Transition Path Sampling Study of the Feruloyl Esterase Mechanism
Lan_2021_J.Agric.Food.Chem_69_5344 Structure-Guided Rational Design of a Mono- and Diacylglycerol Lipase from Aspergillus oryzae: A Single Residue Mutant Increases the Hydrolysis Ability
Mok_2021_Polymers.(Basel)_13_ In Vivo Characterization and Application of the PHA Synthase from Azotobacter vinelandii for the Biosynthesis of Polyhydroxyalkanoate Containing 4-Hydroxybutyrate
Oliart-Ros_2021_Molecules_26_ Production and Characterization of Cross-Linked Aggregates of Geobacillus thermoleovorans CCR11 Thermoalkaliphilic Recombinant Lipase
Zhao_2021_Int.J.Biol.Macromol__ Characterization of a novel lipase from Bacillus licheniformis NCU CS-5 for applications in detergent industry and biodegradation of 2,4-D butyl ester
Hartz_2021_J.Biotechnol__ Development and application of a highly efficient CRISPR-Cas9 system for genome engineering in Bacillus megaterium
Ingenbosch_2021_J.Org.Chem__ Effect of Organic Solvents on the Structure and Activity of a Minimal Lipase
Cui_2021_Angew.Chem.Int.Ed.Engl__ Less unfavorable salt-bridges on the enzyme surface results in more organic cosolvent resistance
Xu_2021_Environ.Pollut_273_116461 An efficient phthalate ester-degrading Bacillus subtilis: Degradation kinetics, metabolic pathway, and catalytic mechanism of the key enzyme
Galmes_2021_ACS.Catal_11_8635 Combined Theoretical and Experimental Study to Unravel the Differences in Promiscuous Amidase Activity of Two Nonhomologous Enzymes
Kim_2021_ChemSusChem_14_4251 Chemo-Biological Upcycling of Poly(ethylene terephthalate) to Multifunctional Coating Materials
Wang_2021_J.Agric.Food.Chem_69_6665 Rational Design for Broadened Substrate Specificity and Enhanced Activity of a Novel Acetyl Xylan Esterase from Bacteroides thetaiotaomicron
Park_2021_Pest.Manag.Sci__ Insecticide resistance trait may contribute to genetic cluster change in Bemisia tabaci MED (Hemiptera: Aleyrodidae) as a potential driving force
Gruber-Dorninger_2021_Toxins.(Basel)_13_ Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme
Li_2021_Enzyme.Microb.Technol_144_109741 Preparation of a Bombyx mori acetylcholinesterase enzyme reagent through chaperone protein disulfide isomerase co-expression strategy in Pichia pastoris for detection of pesticides
Kim_2021_Acta.Crystallogr.D.Struct.Biol_77_1451 The structure of natively iodinated bovine thyroglobulin
Yoshida_2021_Sci.Rep_11_11883 Enhancement of protein thermostability by three consecutive mutations using loop-walking method and machine learning
de Sousa Fonseca_2021_Bioprocess.Biosyst.Eng__ Immobilization of Amano lipase AK from Pseudomonas fluorescens on different types of chitosan-containing supports: use in the kinetic resolution of rac-indanol
Taher_2021_Curr.Res.Struct.Biol_3_72 Biochemical and Structural Characterization of Two Cif-Like Epoxide Hydrolases from Burkholderia cenocepacia
Wrobel_2021_J.Am.Chem.Soc__ Combinatorial Assembly of Modular Glucosides via Carboxylesterases Regulates C. elegans Starvation Survival
Valderrama_2021_J.Mol.Graph.Model_107_107951 Finite-temperature effect in the O-acylation of (R,S)-propranolol catalyzed by Candida antarctica lipase B
Doerr_2021_J.Mol.Model_27_198 Effect of the acyl-group length on the chemoselectivity of the lipase-catalyzed acylation of propranolol-a computational study
Liu_2021_Enzyme.Microb.Technol_148_109818 Synthesis of lipophilic arbutin ester by enzymatic transesterification in high pressure carbon dioxide
Ortega-Rojas_2021_European.J.Org.Chem_2021_4790 Effect of the Substituent and Amino Group Position on the Lipase-Catalyzed Resolution of gamma-Amino Esters: A Molecular Docking Study Shedding Light on Candida antarctica lipase B Enantioselectivity
Poterala_2021_ACS.Sustain.Chem.Eng_9_10276 From Waste to ValueDirect Utilization of alpha-Angelica Lactone as a Nonconventional Irreversible Acylating Agent in a Chromatography-Free Lipase-Catalyzed KR Approach toward sec-Alcohols
Komagata_2021_Insect.Biochem.Mol.Biol__103637 Common substitution mutation F348Y of acetylcholinesterase gene contributes to organophosphate and carbamate resistance in Cimex lectularius and C. hemipterus
Schuiten_2021_ACS.Catal_11_6113 Promiscuous Dehalogenase Activity of the Epoxide Hydrolase CorEH from Corynebacterium sp. C12
Gong_2021_Insect.Sci__ Molecular and functional characterization of three novel carboxylesterases in the detoxification of permethrin in the mosquito, Culex quinquefasciatus
Gravato_2021_Methods.Mol.Biol_2240_119 Acetylcholinesterase (AChE) Activity in Embryos of Zebrafish
Boiangiu_2021_Antioxidants.(Basel)_10_ Anxiolytic, Promnesic, Anti-Acetylcholinesterase and Antioxidant Effects of Cotinine and 6-Hydroxy-L-Nicotine in Scopolamine-Induced Zebrafish (Danio rerio) Model of Alzheimer's Disease
Mit_2021_Sci.Total.Environ_773_144734 Modeling acetylcholine esterase inhibition resulting from exposure to a mixture of atrazine and chlorpyrifos using a physiologically-based kinetic model in fish
Patra_2021_Nanotechnology__ Nanonization of a chemically synthesized flavone HMDF (3-hydroxy-3',4'-methylenedioxyflavone) by entrapping within calcium phosphate nanoparticle (CPNP) and exploring its anti-oxidant role on neural cells in vitro and zebra fish in vivo
Knoll-Gellida_2021_Toxicol.Sci__ Hyperactivity and Seizure Induced by Tricresyl Phosphate Are Isomer-Specific and Not Linked to Phenyl Valerate-Neuropathy Target Esterase Activity Inhibition in Zebrafish
Campanari_2021_Cells_10_ TDP-43 Regulation of AChE Expression Can Mediate ALS-Like Phenotype in Zebrafish
Torres_2021_Neurosci__ gCotreatment of small gold nanoparticles protects against the increase in cerebral acetylcholinesterase activity and oxidative stress induced by acute ethanol exposure in the zebrafish
Maggio_2021_Chemosphere_276_130120 Neurotoxicity of chlorpyrifos and chlorpyrifos-oxon to Daphnia magna
Kumar_2021_Biochemistry_60_1312 A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster
Tortoriello_2021_Cannabis.Cannabinoid.Res_6_119 Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB(1) Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster
Shieh_2021_Fly.(Austin)_15_8 Exploring Excitotoxicity and Regulation of a Constitutively Active TRP Ca(2+) Channel in Drosophila
Zhou_2021_Biomacromolecules__ Synthesis, Characterization, and Simulation of Four-Armed Megamolecules
Savickaite_2021_Int.J.Biol.Macromol_173_421 Immobilized GDEst-95, GDEst-lip and GD-95RM lipolytic enzymes for continuous flow hydrolysis and transesterification reactions
Ishak_2021_PLoS.One_16_e0251751 Structure elucidation and docking analysis of 5M mutant of T1 lipase Geobacillus zalihae
Maiangwa_2021_J.Mol.Graph.Model_105_107897 Enhancing the stability of Geobacillus zalihae T1 lipase in organic solvents and insights into the structural stability of its variants
Savickaite_2021_Int.J.Biol.Macromol_168_261 Study of individual domains' functionality in fused lipolytic biocatalysts based on Geobacillus lipases and esterases
Bai_2021_Pest.Manag.Sci_77_2129 Enhanced hydrolysis of beta-cypermethrin caused by deletions in the glycin-rich region of carboxylesterase 001G from Helicoverpa armigera
Xu_2021_Pestic.Biochem.Physiol_179_104969 Two single mutations in carboxylesterase 001C improve fenvalerate hydrolase activity in Helicoverpa armigera
Hirosawa_2021_Drug.Metab.Dispos__ Role of human AADAC on hydrolysis of eslicarbazepine acetate and effects of AADAC genetic polymorphisms on hydrolase activity
Levano_2021_Mol.Genet.Genomic.Med_9_e1764 Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients
Jiang_2021_J.Int.Med.Res_49_300060521999527 Progesterone activates the cyclic AMP-protein kinase A signalling pathway by upregulating ABHD2 in fertile men
Bjorkgren_2021_Front.Cell.Dev.Biol_9_710864 Alpha\/Beta Hydrolase Domain-Containing Protein 2 regulates the rhythm of follicular maturation and estrous stages of the female reproductive cycle
Bononi_2021_J.Med.Chem_64_9759 alpha\/beta-Hydrolase Domain (ABHD) Inhibitors as New Potential Therapeutic Options against Lipid-Related Diseases
Agwa_2021_Cells_10_ ABHD4-Regulating RNA Panel: Novel Biomarkers in Acute Coronary Syndrome Diagnosis
Deng_2021_Cannabis.Cannabinoid.Res__ ABHD6 Controls Amphetamine-Stimulated Hyperlocomotion: Involvement of CB(1) Receptors
Miralpeix_2021_Br.J.Pharmacol_178_1507 Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
Kokona_2021_Neuropharmacol_185_108450 The endocannabinoid 2-arachidonoylglycerol and dual ABHD6\/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity
Malamas_2021_ChemMedChem__ Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors
Zhang_2021_Front.Pharmacol_12_784202 Alpha\/Beta-Hydrolase Domain-Containing 6: Signaling and Function in the Central Nervous System
Farah_2021_Biochem.Biophys.Res.Commun_591_31 1-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1
Karottki_2021_Metab.Eng_66_114 A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
Luo_2021_Aging.(Albany.NY)_13_20179 Long non-coding RNA ABHD11-AS1 promotes colorectal cancer progression and invasion through targeting the integrin subunit alpha 5\/focal adhesion kinase\/phosphoinositide 3 kinase\/Akt signaling pathway
Wang_2021_Front.Oncol_11_791943 Single-Nucleotide Polymorphisms Promote Dysregulation Activation by Essential Gene Mediated Bio-Molecular Interaction in Breast Cancer
Xue_2021_J.Cell.Physiol_236_2649 m(6) A transferase METTL3-induced lncRNA ABHD11-AS1 promotes the Warburg effect of non-small-cell lung cancer
Zhang_2021_Anticancer.Drugs_32_269 EZH2-mediated lncRNA ABHD11-AS1 promoter regulates the progression of ovarian cancer by targeting miR-133a-3p
Singh_2021_Eur.J.Neurosci__ The loss of enzymatic activity of the PHARC associated lipase ABHD12 results in increased phagocytosis that causes neuroinflammation
Khandelwal_2021_Cell.Chem.Biol__ Fatty acid chain length drives lysophosphatidylserine-dependent immunological outputs
Minamihata_2021_Neurochem.Res__ Increase in Cellular Lysophosphatidylserine Content Exacerbates Inflammatory Responses in LPS-Activated Microglia
Miyake_2021_Clin.Genet__ A homozygous ABHD16A variant causes a complex hereditary spastic paraplegia with developmental delay, absent speech, and characteristic face
Lemire_2021_Am.J.Hum.Genet__ ABHD16A deficiency causes a complicated form of hereditary spastic paraplegia associated with intellectual disability and cerebral anomalies
Yahia_2021_Front.Neurol_12_720201 Pathogenic Variants in ABHD16A Cause a Novel Psychomotor Developmental Disorder With Spastic Paraplegia
Chavarria_2021_Antioxidants.(Basel)_10_329 Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases
McGuire_2021_Chem.Res.Toxicol_34_804 Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6
Blumenthal_2021_J.Biol.Chem__ Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects
Zhou_2021_J.Med.Chem_64_1844 Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate
Gerlits_2021_Curr.Res.Struct.Biol_3_206 Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure
Viayna_2021_J.Med.Chem_64_812 Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP\/PS1 Mice
Wichur_2021_Eur.J.Med.Chem_225_113792 Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT6R antagonists with beta-amyloid anti-aggregation properties
Rossi_2021_J.Med.Chem_64_4972 Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease
El Jellas_2021_J.Clin.Endocrinol.Metab__ Two new mutations in the CEL gene causing diabetes and hereditary pancreatitis: How to correctly identify MODY8 cases
Zhang_2021_Chem.Biol.Interact_351_109744 Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans
Collins_2021_Drug.Metab.Dispos__ Transcriptional regulation of carboxylesterase 1 (CES1) in human liver: role of the nuclear receptor NR1H3 (LXRalpha) and its splice isoforms
Li_2021_Drug.Metab.Dispos__ Contributions of Cathepsin A and Carboxylesterase 1 to the hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis
Chen_2021_J.Pharm.Pharmacol_73_52 Clock gene Bmal1 controls diurnal rhythms in expression and activity of intestinal carboxylesterase 1
Elfiky_2021_J.Crohns.Colitis__ Carboxylesterase-1 assisted targeting of HDAC inhibitors to mononuclear myeloid cells in Inflammatory Bowel Disease
Capece_2021_J.Clin.Invest__ Enhanced triacylglycerol catabolism by Carboxylesterase 1 promotes aggressive colorectal carcinoma
Chen_2021_Sci.Rep_11_13984 Copy number variation in the CES1 gene and the risk of non-alcoholic fatty liver in a Chinese Han population
Zhou_2021_Clin.Transl.Med_11_e449 Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1
Chalhoub_2021_J.Lipid.Res__100075 Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease
Zhang_2021_Chem.Phys.Lett_785_139143 Determination of carboxylesterase 2 by fluorescence probe to guide pancreatic adenocarcinoma profiling
Shi_2021_Eur.J.Drug.Metab.Pharmacokinet_46_129 Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations
Shen_2021_Fundam.Clin.Pharmacol_35_432 Remdesivir potently inhibits carboxylesterase-2 through covalent modifications: signifying strong drug-drug interactions
Song_2021_Front.Pharmacol_12_655659 Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2
Li_2021_Pharmaceutics_13_ Activation of Tenofovir Alafenamide and Sofosbuvir in the Human Lung and Its Implications in the Development of Nucleoside\/Nucleotide Prodrugs for Treating SARS-CoV-2 Pulmonary Infection
Kamnate_2021_J.Anat__ In situ localization of diacylglycerol lipase alpha and beta producing an endocannabinoid 2-arachidonoylglycerol and of cannabinoid receptor 1 in the primary oocytes of postnatal mice
O'Brien_2021_Cannabis.Cannabinoid.Res__ Diacylglycerol Lipase-beta Knockout Mice Display a Sex-Dependent Attenuation of Traumatic Brain Injury-Induced Mortality with No Impact on Memory or Other Functional Consequences
Kise_2021_Nature__ Structural basis of gating modulation of Kv4 channel complexes
Tsai_2021_Acta.Neurol.Taiwan_30(3)_118 Treatable Rapid Progressive Dementia: A First Case Report of Anti-dipeptidyl-peptidase-like Protein 6 Encephalitis in Taiwan
Dean_2021_J.Acad.Consult.Liaison.Psychiatry_62_449 Psychiatric Sequelae of Anti-Dipeptidyl Peptidase-Like Protein-6 Encephalitis: A Case Report and Review of the Literature
Miao_2021_Front.Neurol_12_817896 Clinical Features and Prognosis in Chinese Patients With Dipeptidyl-Peptidase-Like Protein 6 Antibody-Associated Encephalitis
Mbonde_2021_Mult.Scler.Relat.Disord_52_102934 DPPX autoimmune encephalitis: A short report on two patients presenting with classic features of this rare but treatable disease
Ross_2021_J.Appl.Crystallogr_54_895 Aerosol-based ligand soaking of reservoir-free protein crystals
Zhang_2021_Pharmacol.Res_169_105630 Profibrotic mechanisms of DPP8 and DPP9 highly expressed in the proximal renal tubule epithelial cells
Hollingsworth_2021_Nature_592_778 DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
Sharif_2021_Immunity__ Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment
Sharif_2021_Biorxiv__ Structural mechanism of CARD8 regulation by DPP9
Fang_2021_Drug.Metab.Dispos__ Role of epoxide hydrolases and cytochrome P450s on metabolism of KZR-616, a first-in-class selective inhibitor of the immunoproteasome
Lillich_2021_J.Med.Chem_64_17259 Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor gamma Agonists\/Soluble Epoxide Hydrolase Inhibitors
Bzowka_2021_Drug.Discov.Today__ Computational insights into the known inhibitors of human soluble epoxide hydrolase
Edin_2021_J.Biol.Chem_296_100198 Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function
Remsberg_2021_Nat.Chem.Biol__ ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth
Bi_2021_Gene_772_145358 Silencing FAM135B enhances radiosensitivity of esophageal carcinoma cell
Dong_2021_Cancer.Res_81_910 A GRN Autocrine-Dependent FAM135B\/AKT\/mTOR Feedforward Loop Promotes Esophageal Squamous Cell Carcinoma Progression
Schnapp_2021_ChemMedChem_16_630 A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein
Zhang_2021_Front.Med__ Research progress on FASN and MGLL in the regulation of abnormal lipid metabolism and the relationship between tumor invasion and metastasis
Gamblin_2021_Diabetes_70_76 Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy
Potter_2021_Orphanet.J.Rare.Dis_16_235 Enzyme replacement therapy and hematopoietic stem cell transplant: a new paradigm of treatment in Wolman disease
Helderman_2021_Bone__115946 Loss of Function of Lysosomal Acid Lipase (LAL) Profoundly Impacts Osteoblastogenesis and Increases Fracture Risk in Humans
Ezgu_2021_Expert.Opin.Drug.Saf__ Safety of sebelipase alfa for the treatment of lysosomal acid lipase deficiency
Witeck_2021_J.Pediatr.(Rio.J)__ Lysosomal acid lipase deficiency in pediatric patients: A scoping review
Torres_2021_Gastrointest.Endosc__ A rare case of lysosomal acid lipase deficiency diagnosed by endoscopy
Sollier_2021_Eur.J.Endocrinol_184_155 LIPE-related lipodystrophic syndrome: clinical characteristics and disease modelling using adipose stem cells
Muller_2021_Diabetes.Metab.Res.Rev__e3504 A Missense Variant Arg611Cys in LIPE which Encodes Hormone Sensitive Lipase Decreases Lipolysis and Increases Risk of Type 2 Diabetes in American Indians
Gago-Dominguez_2021_Sci.Rep_11_10436 LIPG endothelial lipase and breast cancer risk by subtypes
Hong_2021_Cancer.Gene.Ther_28_27 LIPG: an inflammation and cancer modulator
Wu_2021_Trends.Endocrinol.Metab_32_48 Lipoprotein Lipase and Its Regulators: An Unfolding Story
Leth-Espensen_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2026650118 The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding
Abrami_2021_Nat.Chem.Biol_17_438 Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
Virlogeux_2021_Sci.Adv_7_eabb0799 Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice
Rong_2021_J.Med.Chem__ Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold
League_2021_Front.Neurol_12_651272 Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat
Pruser_2021_Mol.Cancer.Ther_20_787 The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB(1) Cannabinoid Receptor
Ikeda_2021_J.Med.Chem__ Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety
Chen_2021_Acta.Pharm.Sin.B_11_1686 Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping
Xiong_2021_Bioorg.Med.Chem.Lett__127986 Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening
Pavon_2021_Neurobiol.Stress_14_100293 Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex
Dong_2021_PLoS.Pathog_17_e1009645 NDRG1 facilitates lytic replication of Kaposi's sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase
Lage-Vickers_2021_Commun.Biol_4_103 The expression of YWHAZ and NDRG1 predicts aggressive outcome in human prostate cancer
Mustonen_2021_FEBS.J_288_3507 Crystal and solution structure of NDRG1, a membrane-binding protein linked to myelination and tumour suppression
Luo_2021_Technol.Cancer.Res.Treat_20_15330338211033074 MiR-188-3p and miR-133b Suppress Cell Proliferation in Human Hepatocellular Carcinoma via Post-Transcriptional Suppression of NDRG1
Takarada-Iemata_2021_Anat.Sci.Int_96_1 Roles of N-myc downstream-regulated gene 2 in the central nervous system: molecular basis and relevance to pathophysiology
Takarada-Iemata_2021_Neurosci.Lett_743_135563 Abnormal social behavior and altered gene expression in mice lacking NDRG2
Ma_2021_Chin.J.Integr.Med_27_912 Elemene Emulsion Injection Administration Reduces Neuropathic Pain by Inhibiting Astrocytic NDRG2 Expression within Spinal Dorsal Horn
Liu_2021_Rev.Esp.Enferm.Dig_113_524 High expression of NDRG3 correlates with poor prognosis in gastric cancer patients
Peng_2021_FEBS.Open.Bio_11_375 A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA\/VSD) and tetralogy of Fallot (TOF)
Yang_2021_Med.Sci.Monit_27_e928523 Identification of NDRG Family Member 4 (NDRG4) and CDC28 Protein Kinase Regulatory Subunit 2 (CKS2) as Key Prognostic Genes in Adrenocortical Carcinoma by Transcriptomic Analysis
Dang_2021_Front.Cell.Dev.Biol_9_662763 NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas
Zhao_2021_J.Med.Chem_64_11354 Structural Insights into Notum Covalent Inhibition
Choi_2021_J.Bone.Miner.Res__ Notum deletion from late-stage skeletal cells increases cortical bone formation and potentiates skeletal effects of sclerostin inhibition
Flanagan_2021_Nature__ NOTUM from Apc-mutant cells biases clonal competition to initiate cancer
Zhao_2021_Future.Med.Chem__ Small-molecule inhibitors of carboxylesterase Notum
Zhao_2021_Mol.Metab__101201 Notum Deacylates Octanoylated Ghrelin
Bayle_2021_J.Med.Chem__ Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
Nilsson_2021_Am.J.Physiol.Endocrinol.Metab__ Osteocyte- and late Osteoblast-derived NOTUM Reduces Cortical Bone Mass in Mice
Dong_2021_Chem.Phys.Lipids_239_105103 Platelet activating-factor acetylhydrolase II: A member of phospholipase A2 family that hydrolyzes oxidized phospholipids
Li_2021_Anal.Chem_93_8161 Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling
Zhu_2021_Front.Genet_12_693538 Structure and Function of Pancreatic Lipase-Related Protein 2 and Its Relationship With Pathological States
Rosier_2021_iScience_24_103460 Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function
Adaixo_2021_Biorxiv__ Cryo-EM structure of native human thyroglobulin
Zhang_2021_JCI.Insight_6_e148496 Thyroid hormone synthesis continues despite biallelic thyroglobulin mutation with cell death
Guo_2021_Nat.Commun_12_2046 Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling
Fernandez-Penas_2021_Cryst.Growth.Des_21_1698 Production of Cross-Linked Lipase Crystals at a Preparative Scale
Liu_2021_Bioresour.Technol_332_124967 Directed evolution of feruloyl esterase from Lactobacillus acidophilus and its application for ferulic acid production
Zhang_2021_Int.J.Biol.Macromol_184_92 A reverse catalytic triad Asp containing loop shaping a wide substrate binding pocket of a feruloyl esterase from Lactobacillus plantarum
Margus_2021_Ecol.Evol_11_15995 Sequence variation and regulatory variation in acetylcholinesterase genes contribute to insecticide resistance in different populations of Leptinotarsa decemlineata
Hu_2021_Front.Plant.Sci_12_747160 Identification of Conserved and Divergent Strigolactone Receptors in Sugarcane Reveals a Key Residue Crucial for Plant Branching Control
Xing_2021_Enzyme.Microb.Technol_149_109849 Enhancing the thermostability of a mono- and diacylglycerol lipase from Malassizia globose by stabilizing a flexible loop in the catalytic pocket
Li_2021_LWT_151_112118 The enhancement of rice bran oil quality through a novel moderate biorefining process
Yoshida_2021_Nat.Commun_12_1848 Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice
Sakai_2021_Life.Sci_284_119896 Arylacetamide deacetylase as a determinant of the hydrolysis and activation of abiraterone acetate in mice and humans
Lee_2021_Pharmaceutics_13_ Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay
Lian_2021_J.Lipid.Res__100093 Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver
Kesavan_2021_Int.J.Mol.Sci_22_ The Consequences of Soluble Epoxide Hydrolase Deletion on Tumorigenesis and Metastasis in a Mouse Model of Breast Cancer
Wagner_2021_Front.Pharmacol_12_778470 Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation
Khetarpal_2021_PLoS.Genet_17_e1009802 Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins
Gorelik_2021_Sci.Adv_7_eabf4155 Structure of the murine lysosomal multienzyme complex core
Khan_2021_ACS.Infect.Dis_7_2876 Total Synthesis of Tetrahydrolipstatin, Its Derivatives, and Evaluation of Their Ability to Potentiate Multiple Antibiotic Classes against Mycobacterium Species
Zhang_2021_Eur.J.Med.Chem_213_113202 Design and synthesis of mycobacterial pks13 inhibitors: Conformationally rigid tetracyclic molecules
Bowles_2021_Protein.Sci__ Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C
Grininger_2021_Biomolecules_11_1299 Structural Changes in the Cap of Rv0183\/mtbMGL Modulate the Shape of the Binding Pocket
Babin_2021_ACS.Cent.Sci_7_803 Chemiluminescent Protease Probe for Rapid, Sensitive, and Inexpensive Detection of Live Mycobacterium tuberculosis
Hou_2021_Enzyme.Microb.Technol_150_109859 Expression of an alkaline feruloyl esterases from thermophilic Chaetomium thermophilum and its boosting effect on delignification of pulp
Sisaphaithong_2021_Plant.Signal.Behav__2009998 Localized expression of the Dwarf14-like2a gene in rice roots on infection of arbuscular mycorrhizal fungus and hydrolysis of rac-GR24 by the encoded protein
Hu_2021_Plant.Biotechnol.J__ Repressed OsMESL expression triggers reactive oxygen species mediated broad-spectrum disease resistance in rice
Hewage_2021_Org.Lett__ An Enzyme-Mediated Aza-Michael Addition Is Involved in the Biosynthesis of an Imidazoyl Hybrid Product of Conidiogenone B
Lopez-Obando_2021_Plant.Cell__ The Physcomitrium (Physcomitrella) patens PpKAI2L receptors for strigolactones and related compounds function via MAX2-dependent and independent pathways
Bleffert_2021_Biorxiv__ Evidence for a bacterial Lands cycle phospholipase A: Structural and mechanistic insights into membrane phospholipid remodeling
Ahmad_2021_Biorxiv__ Substrate access mechanism in a novel membrane-bound 1 phospholipase A of Pseudomonas aeruginosa concordant with specificity and regioselectivity
Ma'ruf_2021_Biotechnol.Rep.(Amst)_29_e00590 Effect of mutation at oxyanion hole residu (H110F) on activity of Lk4 lipase
Scheel_2021_Front.Bioeng.Biotechnol_9_618259 Optimizing a Fed-Batch High-Density Fermentation Process for Medium Chain-Length Poly(3-Hydroxyalkanoates) in Escherichia coli
Staudt_2021_Microorganisms_9_1780 Rational Design for Enhanced Acyltransferase Activity in Water Catalyzed by the Pyrobaculum calidifontis VA1 Esterase
Noguchi_2021_Cannabis.Cannabinoid.Res__ Phenotypic Characterization of the Endocannabinoid-Degrading Enzyme Alpha\/Beta-Hydrolase Domain 6 Knockout Rat
Huang_2021_Nature__ Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Liu_2021_Mol.Pharmacol__2 Construction and characterization of CRISPR\/Cas9 knockout rat model of carboxylesterase 2a gene
Schenkmayerova_2021_Nat.Commun_12_3616 Engineering the protein dynamics of an ancestral luciferase
Mehrabi_2021_Sci.Adv_7_eabf1380 Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison
Chen_2021_Angew.Chem.Int.Ed.Engl_60_21959 Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase
Wilhelm_2021_Biochemistry_60_2560 Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag
Shaposhnikova_2021_Crystals_11_1052 Stabilization of Haloalkane Dehalogenase Structure by Interfacial Interaction with Ionic Liquids
Deo_2021_Nat.Chem.Biol_17_718 The HaloTag as a general scaffold for far-red tunable chemigenetic indicators
Miro-Vinyals_2021_Chembiochem_22_3398 HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridium Dye
Markova_2021_ACS.Catal_11_12864 Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers
Cogan_2021_Science_374_729 Mapping the catalytic conformations of an assembly-line polyketide synthase module
Bhardwaj_2021_3.Biotech_11_308 Purification of high molecular weight thermotolerant esterase from Serratia sp. and its characterization
Liu_2021_Mol.Catal_514_111851 Remarkable improvement in the regiocomplementarity of a Glycine max epoxide hydrolase by reshaping its substrate-binding pocket for the enantioconvergent preparation of (R)-hexane-1,2-diol
Iermak_2021_Catalysts_11_5 Description of Transport Tunnel in Haloalkane Dehalogenase Variant LinB D147C+L177C from Sphingobium japonicum
Kokkonen_2021_RSC.Chem.Biol_2_645 Substrate inhibition by the blockage of product release and its control by tunnel engineering
Knobloch_2021_Chemosphere_283_131199 Transformation of short-chain chlorinated paraffins and olefins with the bacterial dehalogenase LinB from Sphingobium Indicum - Kinetic models for the homologue-specific conversion of reactive and persistent material
Kaur_2021_Enzyme.Microb.Technol_146_109760 Protocol for in-vitro purification and refolding of hexachlorocyclohexane degrading enzyme haloalkane dehalogenase LinB from inclusion bodies
Miller_2021_Elife_10_e66657 Structure-guided microbial targeting of antistaphylococcal prodrugs
Kumar_2021_PLoS.One_16_e0258106 Staphylococcus aureus Lipase 3 (SAL3) is a surface-associated lipase that hydrolyzes short chain fatty acids
Chang_2021_Extremophiles__ Characterization of a carboxylesterase with hyper-thermostability and alkali-stability from Streptomyces lividans TK24
Tanaka_2021_Int.J.Biol.Macromol_170_343 Exploring mutable conserved sites and fatal non-conserved sites by random mutation of esterase from Sulfolobus tokodaii and subtilisin from Thermococcus kodakarensis
Yoshikawa_2021_Commun.Biol_4_343 Mutations in hik26 and slr1916 lead to high-light stress tolerance in Synechocystis sp. PCC6803
Chen_2021_Proc.Natl.Acad.Sci.U.S.A_118_ Evolution of Ycf54-independent chlorophyll biosynthesis in cyanobacteria
Raji_2021_FEBS.Lett_595_351 The coordinated action of glucuronoyl esterase and alpha-glucuronidase promotes the disassembly of lignin-carbohydrate complexes
Papapostolou_2021_Pest.Manag.Sci_77_666 Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece
Bertolini_2021_Front.Chem_9_771612 Unveiling the Enzymatic Degradation Process of Biobased Thiophene Polyesters
Baath_2021_Biotechnol.Bioeng__ Structure-function analysis of two closely related cutinases from Thermobifida cellulosilytica
Silman_2021_Protein.Sci_30_966 Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif
Kashyap_2021_Enzyme.Microb.Technol_151_109922 Disrupting putative N-glycosylation site N17 in lipase Lip11 of Yarrowia lipolytica yielded a catalytically efficient and thermostable variant accompanying conformational changes
Hirata_2021_Mol.Biol.Cell__mbcE20070500 Atg15 in Saccharomyces cerevisiae consists of two functionally distinct domains
Ramachandran_2021_Biotechnol.Lett_43_279 FSH1 encodes lysophospholipase activity in Saccharomyces cerevisiae
Abokitse_2021_Appl.Environ.Microbiol__ A Novel Actinobacterial Cutinase Containing a Non-Catalytic Polymer-Binding Domain
Yin_2021_Biotechnol.Lett__ Expression and kinetic analysis of carboxylesterase LmCesA1 from Locusta migratoria
Diwo_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2017046118 NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB
Wullich_2021_Chembiochem_22_733 Stabilizing AqdC, a Pseudomonas Quinolone Signal-Cleaving Dioxygenase from Mycobacteria, by FRESCO-Based Protein Engineering
Oda_2021_Biophys.Physicobiol_18_168 Structural basis for Ca(2+)-dependent catalysis of a cutinase-like enzyme and its engineering: application to enzymatic PET depolymerization
Emori_2021_Proteins_89_502 Structural basis of mutants of PET-degrading enzyme from Saccharomonospora viridis AHK190 with high activity and thermal stability
Senga_2021_J.Biochem_169_207 Multiple structural states of Ca2+-regulated PET hydrolase, Cut190, and its correlation with activity and stability
Liu_2021_Toxins.(Basel)_13_874 FumDSB Can Reduce the Toxic Effects of Fumonisin B(1) by Regulating Several Brain-Gut Peptides in Both the Hypothalamus and Jejunum of Growing Pigs
Li_2021_Int.J.Biol.Macromol_169_18 Biological detoxification of fumonisin by a novel carboxylesterase from Sphingomonadales bacterium and its biochemical characterization
Zhou_2021_Front.Immunol_12_670427 Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response
Ye_2021_PeerJ_9_e10919 Putative carboxylesterase gene identification and their expression patterns in Hyphantria cunea (Drury)
Li_2021_Sci.Rep_11_6913 Characterization of a novel sn1,3 lipase from Ricinus communis L. suitable for production of oleic acid-palmitic acid-glycerol oleate
Wurlitzer_2021_Appl.Environ.Microbiol_87_e02051 Bacterial-Like Nonribosomal Peptide Synthetases Produce Cyclopeptides in the Zygomycetous Fungus Mortierella alpina
Koczyk_2021_J.Fungi.(Basel)_7_285 Terpenoid Biosynthesis Dominates among Secondary Metabolite Clusters in Mucoromycotina Genomes
Bi_2021_Cell_184_1377 Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes
Young_2021_Genomics_113_1605 High-quality reference genome for Clonorchis sinensis
Shin_2021_J.Nat.Prod_84_239 Structures and Biosynthetic Pathway of Coprisamides C and D, 2-Alkenylcinnamic Acid-Containing Peptides from the Gut Bacterium of the Carrion Beetle Silpha perforata
Tjora_2021_Eur.J.Gastroenterol.Hepatol_33_839 Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis
Gravdal_2021_J.Biol.Chem_296_100661 The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity
Qu_2021_J.Med.Entomol__ Multiple Genetic Mutations Related to Insecticide Resistance are Detected in Field Kazakhstani House Flies (Muscidae: Diptera)
Inak_2021_Exp.Appl.Acarol__ Geographical distribution and origin of acetylcholinesterase mutations conferring acaricide resistance in Tetranychus urticae populations from Turkey
Talipouo_2021_Sci.Rep_11_7322 High insecticide resistance mediated by different mechanisms in Culex quinquefasciatus populations from the city of Yaound, Cameroon
Medjigbodo_2021_J.Insect.Sci_21_ Interplay Between Oxytetracycline and the Homozygote kdr (L1014F) Resistance Genotype on Fecundity in Anopheles gambiae (Diptera: Culicidae) Mosquitoes
Owuor_2021_PLoS.One_16_e0240771 Insecticide resistance status of indoor and outdoor resting malaria vectors in a highland and lowland site in Western Kenya
Sy_2021_Pestic.Biochem.Physiol_173_104783 Detection of kdr and ace-1 mutations in wild populations of Anopheles arabiensis and An. melas in a residual malaria transmission area of Senegal
Brazzolotto_2021_Pharmacogenomics.J_21_165 Characterization of four BCHE mutations associated with prolonged effect of suxamethonium
Omran_2021_Molecules_26_ New Disulfiram Derivatives as MAGL-Selective Inhibitors
Zappaterra_2021_Int.J.Mol.Sci_22_3066 Biocatalytic Approach for Direct Esterification of Ibuprofen with Sorbitol in Biphasic Media
Delavault_2021_Molecules_26_2759 Lipase-Catalyzed Production of Sorbitol Laurate in a 2-in-1 Deep Eutectic System: Factors Affecting the Synthesis and Scalability
Kaniakova_2021_Biochem.Pharmacol__114460 7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo
Chen_2021_Antioxidants.(Basel)_10_ Effects of Black Garlic Extract and Nanoemulsion on the Deoxy Corticosterone Acetate-Salt Induced Hypertension and Its Associated Mild Cognitive Impairment in Rats
Huong_2021_Crit.Rev.Biotechnol_41_474 P(3HB-co-4HB) as high value polyhydroxyalkanoate: its development over recent decades and current advances
Jung_2021_Bioorg.Med.Chem.Lett_37_127846 Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor
Nekoeinia_2021_Struct.Chem_32_1123 QSAR analysis of the acetylcholinesterase inhibitory activity of some tertiary amine derivatives of cinnamic acid
Dachir_2021_Chem.Biol.Interact_336_109393 Skin decontamination efficacy of sulfur mustard and VX in the pig model: A comparison between Fuller's earth and RSDL
Tsai_2021_J.Food.Drug.Anal_29_153 Determination of glycidyl esters and 3-MCPD esters in edible oils by sample pretreatment with the combination of lipase hydrolysis and modified QuEChERS for GC-MS analysis
Simkova_2021_Eur.J.Med.Chem_224_113717 Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with alpha-ketoamide warheads
Coughlin_2021_Eur.J.Nucl.Med.Mol.Imaging__ First-in-human neuroimaging of soluble epoxide hydrolase using [(18)F]FNDP PET
Al Mamun_2021_Int.J.Mol.Sci_22_ Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies
Muller_2021_ACS.Catal_11_14906 Recent Insights and Future Perspectives on Promiscuous Hydrolases\/Acyltransferases
Bojanowski_2021_JID.Innov_1_100040 A Sensitization-Free Dimethyl Fumarate Prodrug, Isosorbide Di-(Methyl Fumarate), Provides a Topical Treatment Candidate for Psoriasis
Dhaliwal_2021_Inflammopharmacology__ Dimethyl fumarate attenuates 2-VO-induced vascular dementia via activating the Nrf2 signaling pathway in rats
Bhunia_2021_Plant.Mol.Biol_105_247 Functional characterization of two type-1 diacylglycerol acyltransferase (DGAT1) genes from rice (Oryza sativa) embryo restoring the triacylglycerol accumulation in yeast
Gabriele_2021_Life.Sci__119486 Carboxylesterases and arylacetamide deacetylase comparison in human A549, H460, and H727 pulmonary cells
Dai_2021_Dyes.Pigments_192_109444 Detection of carboxylesterase 1 and carbamates with a novel fluorescent protein chromophore based probe
Brandt_2021_Drug.Test.Anal_13_175 Synthetic cannabinoid receptor agonists: Analytical profiles and development of QMPSB, QMMSB, QMPCB, 2F-QMPSB, QMiPSB, and SGT-233
Liu_2021_Eur.J.Med.Chem_229_114095 Discovery of novel beta-carboline derivatives as selective AChE inhibitors with GSK-3beta inhibitory property for the treatment of Alzheimer's disease
Pont_2021_Eur.J.Med.Chem_225_113779 From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
Perone_2021_ChemMedChem_16_187 Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy
Gorecki_2021_ACS.Chem.Neurosci__ Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease
Yip_2021_Br.J.Clin.Pharmacol_87_2572 Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine
Jiang_2021_Adv.Ther__ A Clinical and Budgetary Impact Analysis of Introducing Sugammadex for Routine Reversal of Neuromuscular Blockade in a Hypothetical Cohort in the US
Lemus_2021_J.Pain.Symptom.Manage__ Sugammadex to reverse neuromuscular blockade prior to withdrawal of life support
Chen_2021_J.Surg.Res_270_221 Sugammadex in Colorectal Surgery: A Systematic Review and Meta-analysis
Gu_2021_Ann.Palliat.Med_10_12566 Sugammadex enhances recovery after abdominal surgery in cancer patients: a real-world, observational study
Song_2021_J.Cardiothorac.Surg_16_45 Sugammadex is associated with shorter hospital length of stay after open lobectomy for lung cancer: a retrospective observational study
Furtado_2021_Mol.Neurobiol_58_4615 JM-20 Treatment After Mild Traumatic Brain Injury Reduces Glial Cell Pro-inflammatory Signaling and Behavioral and Cognitive Deficits by Increasing Neurotrophin Expression
Ogidigo_2021_Pharm.Biol_59_444 UPLC-PDA-ESI-QTOF-MS\/MS fingerprint of purified flavonoid enriched fraction of Bryophyllum pinnatum\; antioxidant properties, anticholinesterase activity and in silico studies
Istifli_2021_Molecules_26_2981 Chemical Composition, Antioxidant and Enzyme Inhibitory Activities of Onosma bourgaei and Onosma trachytricha and in Silico Molecular Docking Analysis of Dominant Compounds
Saravanakumar_2021_Plants.(Basel)_10_ Phytochemical Composition, Antioxidant, and Enzyme Inhibition Activities of Methanolic Extracts of Two Endemic Onosma Species
Feng_2021_J.Hazard.Mater_417_125983 Bioremediation of triphenyl phosphate by Pycnoporus sanguineus: Metabolic pathway, proteomic mechanism and biotoxicity assessment
Wang_2021_Chemosphere_275_129978 Triphenyl phosphate disturbs the lipidome and induces endoplasmic reticulum stress and apoptosis in JEG-3 cells
Takemoto_2021_Chem.Pharm.Bull.(Tokyo)_69_819 Molecular Transformation Based on an Innovative Catalytic System
Ding_2021_Expert.Opin.Drug.Metab.Toxicol_17_725 Safety and pharmacokinetic interaction between fotagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin in healthy subjects
Yeh_2021_Life.Sci_278_119574 DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity
Pohanka_2021_Sensors.(Basel)_21_ A Smartphone Camera Colorimetric Assay of Acetylcholinesterase and Butyrylcholinesterase Activity
Wang_2021_Toxicology__152725 Decrease of an intracellular organic osmolyte contributes to the cytotoxicity of organophosphate in neuroblastoma cells in vitro
Guo_2021_Anal.Bioanal.Chem_413_5835 Desorption electrospray ionization (DESI) source coupling ion mobility mass spectrometry for imaging fluoropezil (DC20) distribution in rat brain
Kumar_2021_Front.Pharmacol_12_737137 Five-Decade Update on Chemopreventive and Other Pharmacological Potential of Kurarinone: a Natural Flavanone
Zhang_2021_Anal.Methods_13_2671 A high-throughput screening assay for dipeptidyl peptidase-IV inhibitors using human plasma
He_2021_Nucl.Med.Biol_96-97_S36 Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake
Jankiewicz_2021_Front.Pharmacol_12_744776 Dual sEH\/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity
Hye_2021_Br.J.Pharmacol_178_4468 Multitarget molecule,PTUPB, to treat diabetic nephropathy in rats
Zhao_2021_Front.Med.(Lausanne)_8_761517 COX-2\/sEH Dual Inhibitor PTUPB Alleviates CCl (4) -Induced Liver Fibrosis and Portal Hypertension
Thorne_2021_Mol.Imaging.Biol_23_127 Imaging Butyrylcholinesterase in Multiple Sclerosis
Thingore_2021_Metab.Brain.Dis_36_299 Amelioration of oxidative stress and neuroinflammation in lipopolysaccharide-induced memory impairment using Rosmarinic acid in mice
Karami-Mohajeri_2021_J.Environ.Sci.Health.B__1 Protective effect of Zataria multiflora Boiss. and its main compound, rosmarinic acid, against malathion induced oxidative stress and apoptosis in HepG2 cells
Galili_2021_Plants.(Basel)_10_ Characterization of a Chickpea Mutant Resistant to Phelipanche aegyptiaca Pers. and Orobanche crenata Forsk
Okazawa_2021_J.Pestic.Sci_46_242 Germination stimulatory activity of bacterial butenolide hormones from Streptomyces albus J1074 on seeds of the root parasitic weed Orobanche minor
Wilt_2021_Bioorg.Med.Chem_51_116507 Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase\/fatty acid amide hydrolase inhibitors
Zhang_2021_Bioorg.Chem_116_105387 Design and synthesis of novel tacrine-dipicolylamine dimers that are multiple-target-directed ligands with potential to treat Alzheimer's disease
Scheiner_2021_ChemPhotoChem_5_149 Photopharmacology on Acetylcholinesterase: Novel Photoswitchable Inhibitors with Improved Pharmacological Profiles
Masurkar_2021_J.Am.Geriatr.Soc__ Risk of overactive bladder associated with cholinesterase inhibitors in dementia
Wichur_2021_Eur.J.Med.Chem_225_113783 Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT(6) receptor with anti-aggregation properties against amyloid-beta and tau
Jiang_2021_Eur.J.Med.Chem_223_113735 Novel cannabidiol-carbamate hybrids as selective BuChE inhibitors: Docking-based fragment reassembly for the development of potential therapeutic agents against Alzheimer's disease
Zhang_2021_Anal.Chem__ AND-Logic Strategy for Accurate Analysis of Alzheimer's Disease via Fluorescent Probe Lighted Up by Two Specific Biomarkers
Hartmann_2021_J.Med.Chem_64_2815 Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH\/PPARgamma Modulator
Li_2021_SLAS.Discov__24725552211030897 Identification of Compounds for Butyrylcholinesterase Inhibition
Tyrrell_2021_J.Lipid.Res_62_100094 Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions
Lin_2021_ACS.Chem.Neurosci__ Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22
Yonekawa_2021_Bioorg.Med.Chem.Lett_47_128206 l-Hypaphorine and d-hypaphorine: Specific antiacetylcholinesterase activity in rat brain tissue
Sasaki_2021_Arterioscler.Thromb.Vasc.Biol_41_360 Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models
Vitali_2021_Arterioscler.Thromb.Vasc.Biol_41_377 Controversial Role of Lecithin:Cholesterol Acyltransferase in the Development of Atherosclerosis: New Insights From an LCAT Activator
Remya_2021_Int.J.Biol.Macromol__ Chemical similarity assisted search for acetylcholinesterase inhibitors: Molecular modeling and evaluation of their neuroprotective properties
Honda_2021_Eur.J.Pharm.Sci__105807 Hydrolase activities of cynomolgus monkey liver microsomes and recombinant CES1, CES2, and AADAC
Zhao_2021_Curr.Drug.Metab__ Comparison of the Inhibitory Effects of Clotrimazoleand Ketoconazole against Human Carboxylesterase 2
Johnson_2022_Xenobiotica_52_105 Optimal pH 8.5 to 9 for the Hydrolysis of Vixotrigine and Other Basic Substrates of Carboxylesterase-1 in Human Liver Microsomes
Good_2021_Antimicrob.Agents.Chemother_65_e02479 AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19
Li_2021_Antimicrob.Agents.Chemother__AAC0060221 Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells
Tao_2021_Curr.Res.Pharmacol.Drug.Discov_2_100045 Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside
Shen_2021_Hepatol.Commun__ The COVID-19 medicine remdesivir is therapeutically activated by carboxylesterase-1 AND excessive hydrolysis increases cytotoxicity
Deb_2021_Pharmaceuticals.(Basel)_14_ ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential
Endo_2021_Am.J.Emerg.Med__ Cholinergic crisis caused by ingesting topical carpronium chloride solution: A case report
Scheiner_2021_J.Med.Chem_64_9302 Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model
Montanari_2021_Molecules_26_3254 New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators
Yao_2021_J.Med.Chem__ Discovery of Novel Tacrine-Pyrimidone Hybrids as Potent Dual AChE\/GSK-3 Inhibitors for the Treatment of Alzheimer's Disease
Rudolph_2021_ACS.Omega_6_13466 Aryl N-[w-(6-Fluoroindol-1-yl)alkyl]carbamates as Inhibitors of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and Butyrylcholinesterase: Structure-Activity Relationships and Hydrolytic Stability
Fuhr_2021_Pharmaceutics_13_270 Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug-Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach
Tuzimski_2021_Molecules_26_ Application of HPLC-DAD for In Vitro Investigation of Acetylcholinesterase Inhibition Activity of Selected Isoquinoline Alkaloids from Sanguinaria canadensis Extracts
Honorio_2021_Chem.Biol.Interact__109523 Binding interaction of protoberberine alkaloids against acetylcholinesterase (AChE) using molecular dynamics simulations and QM\/MM calculations
Marasco_2021_Chem.Biol.Interact_334_109300 Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on beta-amyloid aggregation
Li_2021_PLoS.One_16_e0247236 Molecular dynamics investigation of the interaction between Colletotrichum capsici cutinase and berberine suggested a mechanism for reduced enzyme activity
Adefegha_2021_Andrologia__e14074 Berberine modulates crucial erectogenic biomolecules and alters histological architecture in penile tissues of diabetic rats
Adefegha_2021_J.Basic.Clin.Physiol.Pharmacol__ Effects of berberine on cholinesterases and monoamine oxidase activities, and antioxidant status in the brain of streptozotocin (STZ)-induced diabetic rats
Adefegha_2021_J.Complement.Integr.Med__ Comparative effects of berberine and piperine on the neuroprotective potential of neostigmine
Saleh_2021_Curr.Rev.Clin.Exp.Pharmacol_16_139 Berberine Nanoencapsulation Attenuates Hallmarks of Scoplomine Induced Alzheimer's-Like Disease in Rats
Wang_2021_Planta.Med__ Berberine Ameliorates Glucose Metabolism in Diabetic Rats through the alpha7 Nicotinic Acetylcholine Receptor-Related Cholinergic Anti-Inflammatory Pathway
Amitai_2021_Commun.Biol_4_573 Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase
Qian_2021_Bioorg.Med.Chem_40_116187 Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells
Li_2021_J.Med.Chem__ Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection
Xu_2021_Sci.Rep_11_9450 PbCSE1 promotes lignification during stone cell development in pear (Pyrus bretschneideri) fruit
Grinan-Ferre_2021_Int.J.Mol.Sci_22_ Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease
Pasieka_2021_Eur.J.Med.Chem_218_113397 Discovery of multifunctional anti-Alzheimers agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters
Ismaili_2021_ACS.Chem.Neurosci__ (+\/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease
Sun_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109038 A preliminary study on the neurotoxic mechanism of harmine in Caenorhabditis elegans
Biberoglu_2021_J.Turkish.chem.soc.sect.chem_8_435 Kinetics of human butyrylcholinesterase inhibition by 1,9-dimethyl-methylene blue
Gentzsch_2021_ChemMedChem__ Synthesis and Initial Characterization of a Selective, Pseudo-irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer
Zhang_2021_J.Mater.Chem.B__ A highly selective near infrared fluorescent probe for carboxylesterase 2 and its biological applications
Vanova_2021_J.Pharm.Sci__ Determination of K869, a novel oxime reactivator of acetylcholinesterase, in rat body fluids and tissues by liquid-chromatography methods: Pharmacokinetic study
Gorecki_2021_Arch.Toxicol__ Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
Savall_2021_Neurosci.Lett__135697 Potential role of a newly AChE reactivator in the depressive-like behavior induced by malathion
Lv_2021_Int.J.Biol.Macromol_167_1262 Investigation of the inhibitory effect of protostanes on human carboxylesterase 2 and their interaction: Inhibition kinetics and molecular stimulations
Yasuda_2021_Drug.Metab.Pharmacokinet_39_100397 Epicatechin gallate and epigallocatechin gallate are potent inhibitors of human arylacetamide deacetylase
Jiang_2021_J.Food.Sci__ Structural characterization and antioxidant property of enzymatic-transesterification derivatives of (-)-epigallocatechin-3-O-gallate and vinyl laurate
Uniyal_2021_Metab.Brain.Dis__ Epigallocatechin-3-gallate improves chronic alcohol-induced cognitive dysfunction in rats by interfering with neuro-inflammatory, cell death and oxido-nitrosative cascade
Nan_2021_Drug.Des.Devel.Ther_15_2013 Epigallocatechin-3-Gallate Provides Protection Against Alzheimer's Disease-Induced Learning and Memory Impairments in Rats
Singh_2021_Environ.Sci.Pollut.Res.Int__ Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice
Vignaux_2021_Chem.Res.Toxicol__ The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase
Liu_2021_J.Org.Chem__ One-Step Synthesis of 4-Octyl Itaconate through the Structure Control of Lipase
Lukawski_2021_Pol.J.Vet.Sci_24_211 Neurological effects of acute exposure to caffeine and organophosphates in mice
Wang_2021_Clin.Transl.Sci__ Impact of carboxylesterase 1 genetic polymorphism on trandolapril activation in human liver and the pharmacokinetics and pharmacodynamics in healthy volunteers
Brinza_2021_Plants.(Basel)_10_ Baicalein 5,6-Dimethyl Ether Prevents Memory Deficits in the Scopolamine Zebrafish Model by Regulating Cholinergic and Antioxidant Systems
Al-Brakati_2021_Neurotox.Res_39_198 Possible Role of Kaempferol in Reversing Oxidative Damage, Inflammation, and Apoptosis-Mediated Cortical Injury Following Cadmium Exposure
Dey_2021_Vet.Parasitol_296_109461 A kaempferol derivative isolated from Lysimachia ramosa (Wall ex. Duby) induced alteration of acetylcholinesterase and nitric oxide synthase in Raillietina echinobothrida
Siebert_2021_J.Sci.Food.Agric__ Enzymatic Hydrolysis of Kaempferol 3-O-(2'''-O-sinapoyl-beta-sophoroside), the Key Bitter Compound of Rapeseed (Brassica napus L.) Protein Isolate
Monroy-Noyola_2021_Chem.Biol.Interact__109524 DAEH N-terminal sequence of avian serum albumins as catalytic center of Cu (II)-dependent organophosphorus hydrolyzing A-esterase activity
Kang_2021_Environ.Sci.Pollut.Res.Int__ Multiple transcriptomic profiling: potential novel metabolism-related genes predict prepubertal testis damage caused by DEHP exposure
Jiang_2021_Eur.J.Med.Chem_223_113663 Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE\/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine
Jiang_2021_Bioorg.Med.Chem_30_115940 Discovery of potent glycogen synthase kinase 3\/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease
Wang_2021_J.Agric.Food.Chem__ Discovery of a Broad-Spectrum Fluorogenic Agonist for Strigolactone Receptors through a Computational Approach
Rafiqah_2021_Polymers.(Basel)_13_ A Review on Properties and Application of Bio-Based Poly(Butylene Succinate)
Thoen_2021_Clin.Res.Hepatol.Gastroenterol_45_101638 Low levels of Lysosomal Acid Lipase (LAL) activity increases necroinflammation in adult patients with biopsy-proven metabolic associated fatty liver disease
Perin_2021_J.Appl.Polym.Sci_139_e51740 Sustainable textile fibers of bioderived polylactide\/poly(pentamethylene 2,5-furanoate) blends
Nuthikattu_2021_Nutrients_13_ Inhibition of Soluble Epoxide Hydrolase Is Protective against the Multiomic Effects of a High Glycemic Diet on Brain Microvascular Inflammation and Cognitive Dysfunction
Chen_2021_Front.Physiol_12_717119 Soluble Epoxide Hydrolase Inhibitors Regulate Ischemic Arrhythmia by Targeting MicroRNA-1
Davis_2021_Int.J.Mol.Sci_22_ Soluble Epoxide Hydrolase Blockade after Stroke Onset Protects Normal but Not Diabetic Mice
Yang_2021_Int.J.Mol.Sci_22_ Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice
Bergmann_2021_Sci.Rep_11_16555 TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function
Bukhari_2021_Eur.Rev.Med.Pharmacol.Sci_25_3835 1-trifluoromethoxyphenyl-3(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor attenuates high fat diet-induced cardiovascular and metabolic disorders in rats
Liu_2021_Mol.Immunol_140_70 Trelagliptin ameliorates IL-1beta-impaired chondrocyte function via the AMPK\/SOX-9 pathway
Fronza_2021_ACS.Chem.Neurosci_12_109 Effect of QTC-4-MeOBnE Treatment on Memory, Neurodegeneration, and Neurogenesis in a Streptozotocin-Induced Mouse Model of Alzheimer's Disease
Rejc_2021_Theranostics_11_6542 Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease
Gentzsch_2021_Mol.Imaging.Biol__ Synthesis and Initial Characterization of a Reversible, Selective (18)F-Labeled Radiotracer for Human Butyrylcholinesterase
Zakosek Pipan_2021_Sci.Rep_11_18098 Treatment of canine cognitive dysfunction with novel butyrylcholinesterase inhibitor
Murata_2021_Leg.Med.(Tokyo)_53_101929 BIMP affects tubulin structure and causes abnormalities in cell division
Turkez_2021_Curr.Drug.Deliv__ Therapeutic Potential of Ferulic Acid in Alzheimer's Disease
Suciu_2021_Bioorg.Med.Chem.Lett_53_128414 Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation
Liu_2021_Biotechnol.Adv_48_107730 Biodegradation and up-cycling of polyurethanes: Progress, challenges, and prospects
Amin_2021_Biotechnol.Appl.Biochem__ Penicillium fellutanum lipase as a green and ecofriendly biocatalyst for depolymerization of poly (sigma-caprolactone): Biochemical, kinetic, and thermodynamic investigations
Neckermann_2021_Food.Res.Int_145_110395 The efficacy and effect on gut microbiota of an aflatoxin binder and a fumonisin esterase using an in vitro simulator of the human intestinal microbial ecosystem (SHIME)
Selvaraj_2021_Cells_10_3454 The Novel Monoacylglycerol Lipase Inhibitor MJN110 Suppresses Neuroinflammation, Normalizes Synaptic Composition and Improves Behavioral Performance in the Repetitive Traumatic Brain Injury Mouse Model
Du_2021_Eur.J.Med.Chem_223_113678 Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis
Hammock_2021_J.Med.Chem__ Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative
Ding_2021_Bioorg.Med.Chem_41_116216 Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT)
Mashayekhi_2021_Prostaglandins.Other.Lipid.Mediat_158_106604 The soluble epoxide hydrolase inhibitor GSK2256294 decreases the proportion of adipose pro-inflammatory T cells
Luther_2021_Hypertension_78_1092 GSK2256294 Decreases sEH (Soluble Epoxide Hydrolase) Activity in Plasma, Muscle, and Adipose and Reduces F2-Isoprostanes but Does Not Alter Insulin Sensitivity in Humans
McReynolds_2021_Molecules_26_ Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development
Gu_2021_Microb.Cell.Fact_20_14 Molecular, structural and biochemical characterization of a novel recombinant chlorophyllase from cyanobacterium Oscillatoria acuminata PCC 6304
Park_2021_Diabetes.Obes.Metab__ Cardiovascular safety of evogliptin in patients with type 2 diabetes mellitus: a nationwide cohort study
Bajaj_2021_J.Assoc.Physicians.India_69_25 Clinical Evidence of Evogliptin plus Metformin in Management of Type 2 Diabetes mellitus
Hong_2021_Br.J.Clin.Pharmacol_87_2757 Pharmacokinetics and safety of evogliptin in hepatically impaired patients
Siddiqui_2021_Neuropharmacol__108662 Linagliptin, a DPP-4 inhibitor, ameliorates Abeta (1-42) peptides induced neurodegeneration and brain insulin resistance (BIR) via insulin receptor substrate-1 (IRS-1) in rat model of Alzheimer's disease
Mayer_2021_Br.J.Pharmacol_178_878 The dipeptidyl peptidase 4 inhibitor linagliptin ameliorates renal injury and accelerated resolution in a rat model of crescentic nephritis
Komorizono_2021_Diabetes.Obes.Metab_23_832 Metformin dose increase versus added linagliptin in non-alcoholic fatty liver disease and type 2 diabetes: An analysis of the J-LINK study
Bardaweel_2021_Acta.Pharm_71_175 Sitagliptin: a potential drug for the treatment of COVID-19?
Khobragade_2021_Biotechnol.Bioeng__ Promoter Engineering-mediated Tuning of Esterase and Transaminase Expression for the Chemoenzymatic Synthesis of Sitagliptin Phosphate at the kilogram-scale
Liu_2021_J.Endocrinol_248_133 Combined use of GABA and sitagliptin promotes human beta-cell proliferation and reduces apoptosis
Bai_2021_Biomed.Chromatogr_35_e4994 Development and validation of an ultrasensitive LC-MS\/MS method for the quantification of cetagliptin in human plasma and its application in a microdose clinical trial
Lu_2021_Xenobiotica_51_1122 In vitro study of the drug-drug interaction potential of cetagliptin and clinical study of pharmacokinetic interaction of cetagliptin and metformin in healthy volunteers
Wang_2021_Clin.Drug.Investig_41_999 First-in-Human, Single-Ascending Dose and Food Effect Studies to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Cetagliptin, a Dipeptidyl Peptidase-4 Inhibitor for the Treatment of Type 2 Diabetes Mellitus
Hammid_2021_Mol.Pharm__ Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues
Demir Caltekin_2021_J.Obstet.Gynaecol.Res__ The protective effect of JZL184 on ovarian ischemia reperfusion injury and ovarian reserve in rats
Jehle_2021_Int.J.Cardiol_323_243 The endocannabinoid 2-arachidonoylglycerol inhibits endothelial function and repair
Muller-Vahl_2021_Mov.Disord__ Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A 12-Week, Randomized, Controlled Study
Yamasaki_2021_Theranostics_11_9492 Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study
Jacquet_2021_Int.J.Mol.Sci_22_ Enzymatic Decontamination of G-Type, V-Type and Novichok Nerve Agents
Jeong_2021_Molecules_26_3810 Identification and Study of Biomarkers from Novichok-Inhibited Butyrylcholinesterase in Human Plasma
Noort_2021_Chem.Res.Toxicol__ Verification of Exposure to Novichok Nerve Agents Utilizing a Semitargeted Human Butyrylcholinesterase Nonapeptide Assay
Rahmania_2021_Pharm.Sci.Res_8_73 Chemical Properties, Biological Activities and Poisoning Treatment of Novichok: A Review
Luedtke_2021_Crystals_11_1270 Backbone Conformation Shifts in X-ray Structures of Human Acetylcholinesterase upon Covalent Organophosphate Inhibition
Balaei-Kahnamoei_2021_Evid.Based.Complement.Alternat.Med_2021_5965061 Phytochemical Analysis and Evaluation of Biological Activity of Lawsonia inermis Seeds Related to Alzheimer's Disease
Peng_2021_J.Mol.Graph.Model_110_108069 Characterizing the potentially neuronal acetylcholinesterase reactivity toward chiral pyraclofos: Enantioselective insights from spectroscopy, in silico docking, molecular dynamics simulation and per-residue energy decomposition studies
Mak_2021_J.Neurochem__ Promising tacrine\/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget
Liu_2021_Mol.Pharmacol__ Tacrine induces endoplasmic reticulum-stressed apoptosis via disrupting the proper assembly of oligomeric acetylcholinesterase in cultured neuronal cells
Toledo-Ibarra_2021_Fish.Shellfish.Immunol_108_134 Alterations in the non-neuronal cholinergic system induced by in-vitro exposure to diazoxon in spleen mononuclear cells of Nile tilapia (O. niloticus)
Mani_2021_Brain.Sci_12_12 Mahanimbine Improved Aging-Related Memory Deficits in Mice through Enhanced Cholinergic Transmission and Suppressed Oxidative Stress, Amyloid Levels, and Neuroinflammation
Crews_2021_Front.Behav.Neurosci_15_652494 Loss of Basal Forebrain Cholinergic Neurons Following Adolescent Binge Ethanol Exposure: Recovery With the Cholinesterase Inhibitor Galantamine
Dail_2021_J.Biochem.Mol.Toxicol__e22755 Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression
Song_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1181_122922 A strategy to discover lead chemome from traditional Chinese medicines based on natural chromatogram-effect correlation (NCEC) and natural structure-effect correlation (NSEC): Mahonia bealei and Mahonia fortunei as a case study
Tan_2021_J.Chromatogr.Sci__ UHPLC With On-Line Coupled Biochemical Detection for High Throughput Screening of Acetylcholinesterase Inhibitors in Coptidis Rhizoma and Cortex Phellodendri
Ghiam_2021_Front.Neurosci_15_635483 Drug Repurposing in the Treatment of Traumatic Brain Injury
Zueva_2021_Chem.Biol.Interact_345_109558 Protective effects of m-(tert-butyl) trifluoroacetophenone, a transition state analogue of acetylcholine, against paraoxon toxicity and memory impairments
Xuan_2021_ACS.Chem.Neurosci_12_2462 Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand To Treat Alzheimer's Disease
Dang_2021_J.Econ.Entomol__ Multiple Mechanisms Conferring Broad-Spectrum Insecticide Resistance in the Tropical Bed Bug (Hemiptera: Cimicidae)
Schluep_2021_Insects_12_ Metabolic Resistance in Permethrin-Resistant Florida Aedes aegypti (Diptera: Culicidae)
Garlet_2021_Pest.Manag.Sci__ Field-evolved resistance to chlorpyrifos by Spodoptera frugiperda (Lepidoptera: Noctuidae): inheritance mode, cross-resistance patterns, and synergism
Sakai_2021_J.Pharm.Sci__ Assessment of drug-drug interaction and optimization in capecitabine and irinotecan combination regimen using a physiologically based pharmacokinetic model
Shih_2021_Toxicol.Appl.Pharmacol__115443 The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs
Kassa_2021_Acta.Medica.(Hradec.Kralove)_64_145 A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats
Bennion_2021_Sci.Rep_11_15567 Development of a CNS-permeable reactivator for nerve agent exposure: an iterative, multi-disciplinary approach
Shyong_2021_J.Pharmacol.Exp.Ther__ Enhancing target tissue levels and diminishing plasma clearance of ionizing zwitterionic antidotes in organophosphate exposures
Feschuk_2021_Toxicol.Lett_349_109 Comparative efficacy of Reactive Skin Decontamination Lotion (RSDL): A systematic review
Jung_2021_J.Biol.Eng_15_9 An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases
Hou_2021_Exp.Mol.Pathol_121_104658 Overexpression of serum lncRNA-ABHD11-AS1 as poor prognosis of patients with papillary thyroid carcinoma
Saleem_2021_Nat.Prod.Res_35_664 New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)
Li_2021_Nat.Prod.Res_35_763 (-)-Grandiflorimine, a new dibenzopyrrocoline alkaloid with cholinesterase inhibitory activity from Illigera grandiflora
Turkan_2021_J.Biomol.Struct.Dyn_39_3277 Inhibition effects of isoproterenol, chlorpromazine, carbamazepine, tamoxifen drugs on Glutathione S- transferase, Cholinesterases enzymes and molecular docking studies
Turkan_2021_J.Biomol.Struct.Dyn_39_3693 Determination of anticancer properties and inhibitory effects of some metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, alpha glycosidase of some compounds with molecular docking study
Anjos_2021_Rev.Paul.Pediatr_39_e2019262 SEVERE ACUTE TOXIC EXPOSURES IN CHILDREN AND ADOLESCENTS: CASE SERIES
Monroy-Noyola_2021_Front.Biosci.(Landmark.Ed)_26_744 Hydrolysis of chiral organophosphorus compounds by phosphotriesterases and mammalian paraoxonase-1
Olofinnade_2021_Front.Biosci.(Landmark.Ed)_26_537 Corylus avellana L. modulates neurobehaviour and brain chemistry following high-fat diet
Olofinnade_2021_Front.Biosci.(Elite.Ed)_13_54 Cucumeropsis mannii reverses high-fat diet induced metabolic derangement and oxidative stress
Sharma_2021_Talanta_221_121267 Sensing platform for pico-molar level detection of ethyl parathion using Au-Ag nanoclusters based enzymatic strategy
Xiao_2021_Talanta_221_121362 A thiamine-triggered fluormetric assay for acetylcholinesterase activity and inhibitor screening based on oxidase-like activity of MnO(2) nanosheets
Tkacz_2021_Food.Chem_338_128105 Anti-diabetic, anti-cholinesterase, and antioxidant potential, chemical composition and sensory evaluation of novel sea buckthorn-based smoothies
Purgatorio_2021_ChemMedChem_16_589 Evaluation of water-soluble Mannich base prodrugs of 2,3,4,5-tetrahydroazepino[4,3-b]indol-1(6H)-one as multitarget-directed agents for Alzheimer's disease
Tsagkaris_2021_Talanta_222_121535 A microfluidic paper-based analytical device ( PAD) with smartphone readout for chlorpyrifos-oxon screening in human serum
Ferreira_2021_Neurotox.Res_39_327 Effect of Proline on Cell Death, Cell Cycle, and Oxidative Stress in C6 Glioma Cell Line
Knobloch_2021_Chemosphere_262_128288 Transformation of short-chain chlorinated paraffins by the bacterial haloalkane dehalogenase LinB - Formation of mono- and di-hydroxylated metabolites
Ahuja-Casarin_2021_J.Enzyme.Inhib.Med.Chem_36_138 Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
Chen_2021_J.Hazard.Mater_402_123830 Broad-spectrum pesticide screening by multiple cholinesterases and thiocholine sensors assembled high-throughput optical array system
Sukumaran_2021_J.Enzyme.Inhib.Med.Chem_36_130 Analogues of 2'-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase
Alex_2021_Anal.Chim.Acta_1142_73 An ultra-sensitive and selective AChE based colorimetric detection of malathion using silver nanoparticle-graphene oxide (Ag-GO) nanocomposite
Guimaraes_2021_J.Hazard.Mater_403_123864 Nanopolystyrene particles at environmentally relevant concentrations causes behavioral and biochemical changes in juvenile grass carp (Ctenopharyngodon idella)
Liu_2021_Food.Funct_12_144 Isoleucine increases muscle mass through promoting myogenesis and intramyocellular fat deposition
Wang_2021_J.Hazard.Mater_403_123921 Preparation and properties of a dual-function cellulose nanofiber-based bionic biosensor for detecting silver ions and acetylcholinesterase
Zheng_2021_Carbohydr.Polym_253_117255 Metabolic degradation of lentinan in liver mediated by CYP450 enzymes and epoxide hydrolase
Azevedo_2021_Chemosphere_263_128029 Effects of pyriproxyfen on zebrafish brain mitochondria and acetylcholinesterase
Chandana_2021_Talanta_223_121701 Comprehensive bioanalytical multi-imaging by planar chromatography in situ combined with biological and biochemical assays highlights bioactive fatty acids in abelmosk
Dai_2021_Talanta_223_121744 Construction of a red emission fluorescent protein chromophore-based probe for detection of carboxylesterase 1 and carbamate pesticide in culture cells
Guo_2021_Chemosphere_263_128270 iTRAQ and PRM-based comparative proteomic profiling in gills of white shrimp Litopenaeus vannamei under copper stress
Li_2021_Chemosphere_263_128238 The association between toxic pesticide environmental exposure and Alzheimer's disease: A scientometric and visualization analysis
Ligaj_2021_Talanta_223_121749 Electrochemical screening of genoprotective and antioxidative effectiveness of Origanum vulgare L. and its functionality in the prevention of neurodegenerative disorders
Moricz_2021_J.Chromatogr.A_1635_461727 Bioactive clerodane diterpenes of giant goldenrod (Solidago gigantea Ait.) root extract
You_2021_FASEB.J_35_e21205 CRISPR\/Cas9-mediated genome editing of Schistosoma mansoni acetylcholinesterase
Yavasoglu_2021_Pestic.Biochem.Physiol_171_104746 The first implementation of allele-specific primers for detecting the knockdown and acetylcholinesterase target site mutations in malaria vector, Anopheles sacharovi
Adefegha_2021_Metab.Brain.Dis__ Moringa oleifera modulates cholinergic and purinergic enzymes activity in BV-2 microglial cells
Behairy_2021_Ecotoxicol.Environ.Saf_208_111620 Di(2-ethylhexyl) adipate plasticizer triggers hepatic, brain, and cardiac injury in rats: Mitigating effect of Peganum harmala oil
Brejchova_2021_Proc.Natl.Acad.Sci.U.S.A_118_ Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides
Carvalho_2021_Biometals__ Conjugates of desferrioxamine and aromatic amines improve markers of iron-dependent neurotoxicity
Chen_2021_Ecotoxicol.Environ.Saf_208_111747 Impacts of chronic exposure to sublethal diazepam on behavioral traits of female and male zebrafish (Danio rerio)
Choi_2021_J.Agric.Food.Chem__ Integral Stereoselectivity of Lipase Based on the Chromatographic Resolution of Enantiomeric\/Regioisomeric Diacylglycerols
El-Sarnagawy_2021_Cardiovasc.Toxicol__ Validation of Corrected and Dispersed QT as Predictors of Adverse Outcomes in Acute Cardiotoxicities
Gholivand_2021_Mol.Divers__2 Monophosphoramide derivatives: synthesis and crystal structure, theoretical and experimental studies of their biological effects
Hauser-Davis_2021_Ecotoxicol.Environ.Saf_208_111589 Biochemical metal accumulation effects and metalloprotein metal detoxification in environmentally exposed tropical Perna perna mussels
Helal_2021_J.Genet.Eng.Biotechnol_19_1 Lipase from Rhizopus oryzae R1: in-depth characterization, immobilization, and evaluation in biodiesel production
Khoma_2021_Ecotoxicol.Environ.Saf_208_111695 Common and particular biochemical responses of Unio tumidus to herbicide, pharmaceuticals and their combined exposure with heating
Kumar_2021_Talanta_224_121906 Pseudosterase activity-based specific detection of human serum albumin on gel
Madboli_2021_Environ.Sci.Pollut.Res.Int__ Immunohistochemical, histopathological, and biochemical studies of the NF-kappaB P65 marker in rat ovaries experimentally intoxicated by cadmium and the protective effect of the purslane plant extract
Mang'era_2021_Parasit.Vectors_14_1 Transcriptomic response of Anopheles gambiae sensu stricto mosquito larvae to Curry tree (Murraya koenigii) phytochemicals
Qu_2021_Talanta_224_121831 Determination of butyrylcholinesterase activity based on thiamine luminescence modulated by MnO(2) nanosheets
Recart_2021_Int.J.Dev.Neurosci__ Gallic acid protects cerebral cortex, hippocampus, and striatum against oxidative damage and cholinergic dysfunction in an experimental model of manic-like behavior: comparison with lithium effects
Reyna_2021_Ecotoxicol.Environ.Saf_208_111603 What does the freshwater clam, Corbicula largillierti, have to tell us about chlorothalonil effects?
Siebert_2021_Talanta_224_121773 Dual electrophoretically-mediated microanalysis in multiple injection mode for the simultaneous determination of acetylcholinesterase and alpha-glucosidase activity applied to selected polyphenols
Titov_2021_ACS.Chem.Neurosci__ Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents
Yang_2021_Ecotoxicol.Environ.Saf_208_111700 Molecular and behavioral responses of zebrafish embryos\/larvae after sertraline exposure
Al-Hazmi_2021_Metab.Brain.Dis__ Biochemical, histological, and neuro-physiological effects of long-term aluminum chloride exposure in rats
Arshad_2021_Biomolecules_11_ RP-UHPLC-MS Chemical Profiling, Biological and In Silico Docking Studies to Unravel the Therapeutic Potential of Heliotropium crispum Desf. as a Novel Source of Neuroprotective Bioactive Compounds
Atamanalp_2021_Toxicol.Mech.Methods__1 Treatment of Oxidative Stress, Apoptosis, and DNA Injury with N-acetylcysteine at simulative pesticide toxicity in fish
Bal_2021_Arch.Pharm.(Weinheim)__e2000422 Synthesis, characterization, crystal structure, alpha-glycosidase, and acetylcholinesterase inhibitory properties of 1,3-disubstituted benzimidazolium salts
Bergamaschi_2021_Clin.Exp.Med__1 Anemia in patients with Covid-19: pathogenesis and clinical significance
Bilal_2021_Food.Chem_346_128894 An insect acetylcholinesterase biosensor utilizing WO(3)\/g-C(3)N(4) nanocomposite modified pencil graphite electrode for phosmet detection in stored grains
Bortolami_2021_Expert.Opin.Ther.Pat__ Acetylcholinesterase inhibitors for the treatment of Alzheimer's disease - a patent review (2016-present)
Campora_2021_ACS.Chem.Neurosci__ Multitarget Biological Profiling of New Naphthoquinone and Anthraquinone-Based Derivatives for the Treatment of Alzheimer's Disease
Chupeerach_2021_Foods_10_ The Effect of Steaming and Fermentation on Nutritive Values, Antioxidant Activities, and Inhibitory Properties of Tea Leaves
Costa_2021_Annu.Rev.Pharmacol.Toxicol_61_1 Introduction to the Theme Old and New Toxicology: Interfaces with Pharmacology
de Souza Cardoso_2021_Mol.Cell.Endocrinol__111157 Neuroprotection elicited by resveratrol in a rat model of hypothyroidism: possible involvement of cholinergic signaling and redox status
Dellali_2021_Environ.Sci.Pollut.Res.Int_28_18176 Effects of Au\/TiO(2) metallic nanoparticles on Unio ravoisieri: assessment through an oxidative stress and toxicity biomarkers
Djebbi_2021_Environ.Sci.Pollut.Res.Int__ Effects of nickel oxide nanoparticles on survival, reproduction, and oxidative stress biomarkers in the marine calanoid copepod Centropages ponticus under short-term exposure
Efremenko_2021_Toxins.(Basel)_13_ Using Cholinesterases and Immobilized Luminescent Photobacteria for the Express-Analysis of Mycotoxins and Estimating the Efficiency of Their Enzymatic Hydrolysis
Epstein_2021_BMC.Pulm.Med_21_1 MiR-608 overexpression in idiopathic pulmonary fibrosis (IPF)
Fabrello_2021_Mar.Environ.Res_165_105247 Effects of a mixture of glyphosate, 17alpha-ethynylestradiol and amyl salicylate on cellular and biochemical parameters of the mussel Mytilus galloprovincialis
Frangiamore_2021_Neurol.Sci__ Iatrogenic Kaposi's sarcoma in myasthenia gravis: learnings from two case reports
Hassan_2021_Mol.Divers__ New organosulfur metallic compounds as potent drugs: synthesis, molecular modeling, spectral, antimicrobial, drug likeness and DFT analysis
Herr_2021_Drugs.Aging__ Removal of Drugs for Alzheimer's Disease from the List of Reimbursable Drugs in France: Analysis of Change in Drug Use, Disease Management and Cognition Using the National Alzheimer Data Bank (BNA)
Huang_2021_Analyst__ Single-cell-resolved measurement of enzyme activity at the tissue level using drop-on-demand microkits
Jalili-Baleh_2021_Daru__ Chromone-lipoic acid conjugate: Neuroprotective agent having acceptable butyrylcholinesterase inhibition, antioxidant and copper-chelation activities
Kowalczyk_2021_Biomacromolecules__ Dual Effect of Prussian Blue Nanoparticles on Abeta40 Aggregation: beta-Sheet Fibril Reduction and Copper Dyshomeostasis Regulation
Kumar_2021_Saudi.J.Biol.Sci_28_754 Cholinesterase inhibitory activity of highly functionalized fluorinated spiropyrrolidine heterocyclic hybrids
Lee_2021_Eur.J.Clin.Pharmacol__ Post-market utilization patterns of Alzheimer's disease treatments in South Korea: comparison with countries with universal health coverage
Liu_2021_Analyst_145_7849 Cu(2+)-Regulated reversible coordination interaction of GQD@Tb\/GMP ICP nanoparticles: towards directly monitoring cerebrospinal acetylcholinesterase as a biomarker for cholinic brain dysfunction
Liu_2021_Nanoscale__ Red-to-blue paper-based colorimetric sensor integrated with smartphone for point-of-use analysis of cerebral AChE upon Cd(2+) exposure
Liu_2021_J.Nat.Med__ Stilbenoids isolated from the roots of Rheum lhasaense under the guidance of the acetylcholinesterase inhibition activity
Marinho_2021_Fish.Physiol.Biochem__ Toxicity of silver nanoparticles on different tissues in adult Danio rerio
Mohamed_2021_BMJ.Case.Rep_14_ Anaesthetic management of a patient with eosinophilic granulomatosis with polyangiitis for internal fixation of a fractured femur
Olajide_2021_J.Mol.Neurosci__ Hippocampal Degeneration and Behavioral Impairment During Alzheimer-Like Pathogenesis Involves Glutamate Excitotoxicity
Oliveira_2021_Ecotoxicol.Environ.Saf_210_111868 Exposure to tricyclic antidepressant nortriptyline affects early-life stages of zebrafish (Danio rerio)
Perri_2021_Am.J.Hosp.Palliat.Care__1049909120985115 Cholinesterase Inhibitor Use in Patients With Dementia Admitted to a Palliative Care Unit
Pyun_2021_Alzheimers.Res.Ther_13_10 Change in cognitive function according to cholinesterase inhibitor use and amyloid PET positivity in patients with mild cognitive impairment
Rehman_2021_Saudi.J.Biol.Sci_28_592 Biochemical Profiling and Elucidation of Biological Activities of Beta vulgaris L. Leaves and Roots Extracts
Sasidharan_2021_J.Enzyme.Inhib.Med.Chem_36_188 Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations
Silva_2021_Environ.Sci.Pollut.Res.Int__ Protective effect of gamma-oryzanol against manganese-induced toxicity in Drosophila melanogaster
Taylor_2021_Annu.Rev.Pharmacol.Toxicol_61_25 Cholinergic Capsules and Academic Admonitions
Tuncsoy_2021_Bull.Environ.Contam.Toxicol__ Impacts of Titanium Dioxide Nanoparticles on Serum Parameters and Enzyme Activities of Clarias gariepinus
Verma_2021_Biochimie__ Current perspectives for microbial lipases from extremophiles and metagenomics
Yoshimaru_2021_Pediatr.Int__ Reevaluation of Concurrent AChE and HE staining for Hirschsprung's disease
Zaragoza-Puchol_2021_Molecules_26_ Alkaloids Analysis of Habranthus cardenasianus (Amaryllidaceae), Anti-Cholinesterase Activity and Biomass Production by Propagation Strategies
Arafa_2021_Vet.Parasitol_290_109346 Control of Rhipicephalus annulatus resistant to deltamethrin by spraying infested cattle with synergistic eucalyptus essential oil-thymol-deltamethrin combination
Labban_2021_Behav.Brain.Res__113100 Effects of Melatonin and Resveratrol on Recognition Memory and Passive Avoidance Performance in a Mouse Model of Alzheimer's Disease
Mitric_2021_Bull.Environ.Contam.Toxicol__ Sampling Site Specific Biomarker Responses in Mediterranean Mussels from the Adriatic Sea
Olivos_2021_Pediatr.Surg.Int__ Current practice of rectal biopsies for the diagnosis of Hirschsprung's disease in Latin America: an international online survey
Patil_2021_Indian.J.Pediatr__ Lipoprotein Lipase Deficiency: Diet is the Key!
Pekkoc_2021_Immunol.Invest__1 Evaluation of IL1B rs1143634 and IL6 rs1800796 Polymorphisms with Autism Spectrum Disorder in the Turkish Children
Scott_2021_Am.J.Trop.Med.Hyg__ Characterization of Pyrethroid Resistance Mechanisms in Aedes aegypti from the Florida Keys
Zhang_2021_Biomacromolecules__ Substrate Engineering in Lipase-Catalyzed Selective Polymerization of d-\/l-Aspartates and Diols to Prepare Helical Chiral Polyester
Badwal_2021_J.Geriatr.Psychiatry.Neurol__891988720988916 Psychosis Management in Lewy Body Dementia: A Comprehensive Clinical Approach
Castagna_2021_J.Alzheimers.Dis__ A Retrospective Study on the Benefits of Combined Citicoline, Memantine, and Acetylcholinesterase Inhibitor Treatments in Older Patients Affected with Alzheimer's Disease
Chakraborty_2021_Soft.Matter__ Lipase sensing by naphthalene diimide based fluorescent organic nanoparticles: a solvent induced manifestation of self-assembly
Dhar_2021_Dysphagia__ Effects of Pyridostigmine on Esophageal and Pharyngeal Motility in Dysphagic Patients Undergoing High-Resolution Manometry
Farag_2021_Neurochem.Res__ Metabolomic Profiling and Neuroprotective Effects of Purslane Seeds Extract Against Acrylamide Toxicity in Rat's Brain
Gad_2021_Plants.(Basel)_10_ GC-MS Based Identification of the Volatile Components of Six Astragalus Species from Uzbekistan and Their Biological Activity
Ghimire_2021_Arch.Microbiol__ Complete genome sequencing and comparative CAZyme analysis of Rhodococcus sp. PAMC28705 and PAMC28707 provide insight into their biotechnological and phytopathogenic potential
Hiremathad_2021_Chem.Biodivers__ Multi-Targeting Tacrine Conjugates with Cholinesterase and Amyloid-Beta Inhibitory Activities: New Anti-Alzheimer's Agents
Ibrahim_2021_Biomarkers__1 Quercetin ameliorates the hepatic apoptosis of fetal rats induced by in utero exposure to fenitrothion via the transcriptional regulation of paraoxonase-1 and apoptosis-related genes
Ilyas_2021_Sci.Rep_11_1708 Effect of Berberis vulgaris L. root extract on ifosfamide-induced in vivo toxicity and in vitro cytotoxicity
Innok_2021_J.Comput.Aided.Mol.Des__ In silico and in vitro anti-AChE activity investigations of constituents from Mytragyna speciosa for Alzheimer's disease treatment
Liu_2021_Asian.J.Androl_23_109 Clinical significance of EPHX2 deregulation in prostate cancer
Mella_2021_Nat.Prod.Res__1 Acetylcholinesterase inhibitory activity from Amaryllis belladonna growing in Chile: enzymatic and molecular docking studies
Miles_2021_Chem.Biol.Drug.Des__ Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database
Nevskaya_2021_Molecules_26_ Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential
Ni_2021_Protein.J__ QSSR Modeling of Bacillus Subtilis Lipase A Peptide Collision Cross-Sections in Ion Mobility Spectrometry: Local Descriptor Versus Global Descriptor
Othman_2021_Nat.Prod.Res__1 Bassiamide A, a new alkaloid from xero-halophyte Bassia indica Wight
Pradhan_2021_BMJ.Case.Rep_14_ Hereditary pseudocholinesterase deficiency discovery after electroconvulsive therapy
Saad_2021_ACG.Case.Rep.J_8_e00516 The Emerging Battle: Lysosomal Acid Lipase Deficiency vs Familial Hypercholesterolemia in Children
Sanchez Montero _2021_Eur.J.Pharmacol__173875 Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease
Sato_2021_Toxicology__152679 Non-linear model analysis of the relationship between cholinesterase activity in rats exposed to 2, 2-dichlorovinyl dimethylphosphate (dichlorvos) and its metabolite concentrations in urine
Schilcher_2021_Int.J.Mol.Sci_22_ Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL
Singh_2021_Eur.J.Pharmacol__173876 16-Substituted steroids alleviate LPS-induced neurodegenerative disorders in rats
Skrzypek_2021_Bioorg.Chem_107_104617 Biological evaluation and molecular docking of novel 1,3,4-thiadiazole-resorcinol conjugates as multifunctional cholinesterases inhibitors
Sladek_2021_Neuropharmacol_185_108455 Modulation of single cell circadian response to NMDA by diacylglycerol lipase inhibition reveals a role of endocannabinoids in light entrainment of the suprachiasmatic nucleus
Smaili_2021_Nat.Prod.Res__1 Chemical constituents and anticholinesterase activity of the essential oil of Algerian Elaeoselinum thapsioides (desf.) maire
Soni_2021_Biotechnol.Appl.Biochem__ Trends in lipase engineering for enhanced biocatalysis
Stephenson_2021_Eur.J.Med.Chem_213_113135 Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma
Yamazaki_2021_Bioorg.Med.Chem_32_115991 Novel arylcarbamate-N-acylhydrazones derivatives as promising BuChE inhibitors: Design, synthesis, molecular modeling and biological evaluation
Zahir_2021_Life.(Basel)_11_ Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
Takahashi_2021_Int.J.Mol.Sci_22_ Multiple Roles for Cholinergic Signaling from the Perspective of Stem Cell Function
Alexandris_2021_Toxicol.Rep_8_73 Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions
Steffen_2021_Mol.Neurobiol__ The gamma-Protocadherins Interact Physically and Functionally with Neuroligin-2 to Negatively Regulate Inhibitory Synapse Density and Are Required for Normal Social Interaction
Vanacek_2021_bioRxiv__ Functional Annotation of an Enzyme Family by Integrated Strategy Combining Bioinformatics with Microanalytical and Microfluidic Technologies
Adedara_2021_Environ.Sci.Pollut.Res.Int__ Chronic ciprofloxacin and atrazine co-exposure aggravates locomotor and exploratory deficits in non-target detritivore speckled cockroach (Nauphoeta cinerea)
Ajayi_2021_Metabol.Open_9_100077 High-fat diet-induced memory impairment and anxiety-like behavior in rats attenuated by peel extract of Ananas comosus fruit via atheroprotective, antioxidant and anti-inflammatory actions
Ali_2021_Neurochem.Res__ Screening of Synthetic Isoxazolone Derivative Role in Alzheimer's Disease: Computational and Pharmacological Approach
Angeloni_2021_Plants.(Basel)_10_ Phytochemical Profile and Biological Activities of Crude and Purified Leonurus cardiaca Extracts
Banno_2021_Nephrol.Ther__ Risk factors for peritoneal dialysis withdrawal due to peritoneal dialysis-related peritonitis
Campora_2021_Pharmaceuticals.(Basel)_14_ Journey on Naphthoquinone and Anthraquinone Derivatives: New Insights in Alzheimer's Disease
Cao_2021_Environ.Sci.Technol__ Can Organophosphates and Carbamates Cause Synergisms by Inhibiting Esterases Responsible for Biotransformation of Pyrethroids?
Castagna_2021_Clin.Drug.Investig__ The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease
David_2021_J.Enzyme.Inhib.Med.Chem_36_491 Discovery of new acetylcholinesterase inhibitors for Alzheimer's disease: virtual screening and in vitro characterisation
do Canto_2021_J.Mol.Model_27_46 Computational studies of polyurethanases from Pseudomonas
Elshafie_2021_Plants.(Basel)_10_ Study of Bio-Pharmaceutical and Antimicrobial Properties of Pomegranate (Punica granatum L.) Leathery Exocarp Extract
Epstein_2021_Toxicol.Lett__ Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR
Floris_2021_J.Enzyme.Inhib.Med.Chem_36_517 Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
Gallego_2021_Chemosphere_271_129399 Enzymatic activity changes in striped catfish Pseudoplatystoma magdaleniatum, induced by exposure to different concentrations of ibuprofen and triclosan
Grau-Bove_2021_PLoS.Genet_17_e1009253 Resistance to pirimiphos-methyl in West African Anopheles is spreading via duplication and introgression of the Ace1 locus
Hagen_2021_PLoS.Pathog_17_e1009286 Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis
Hansen_2021_Thorax__ Organophosphate and carbamate insecticide exposure is related to lung function change among smallholder farmers: a prospective study
Hwang_2021_Nutrients_13_ Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches
Islam_2021_Mar.Environ.Res_164_105249 Perfluorooctane sulfonic acid (PFOS) adsorbed to polyethylene microplastics: Accumulation and ecotoxicological effects in the clam Scrobicularia plana
Kamdi_2021_Cytokine_139_155408 Phloridzin attenuates lipopolysaccharide-induced cognitive impairment via antioxidant, anti-inflammatory and neuromodulatory activities
Kim_2021_Environ.Toxicol.Pharmacol__103597 Salinity-mediated changes in hematological parameters, stress, antioxidant responses, and acetylcholinesterase of juvenile olive flounders (Paralichthys olivaceus)
Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437 Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates
Leineweber_2021_J.Zoo.Wildl.Med_51_948 Clinical chemistry, vitamin, electrophoresis, and hematologic analytes of black-headed ibis (Threskiornis melanocephalus)
Li_2021_Ann.Thorac.Surg__ Outcomes of juvenile myasthenia gravis: a comparison of robotic thymectomy with medication treatment
Li_2021_Chem.Biol.Interact__109392 Neuroprotective effects of protocatechuic acid on sodium arsenate induced toxicity in mice: Role of oxidative stress, inflammation, and apoptosis
Liu_2021_Chem.Res.Toxicol__ LC-MS\/MS Analysis of the Formation and Loss of DNA Adducts in Rats Exposed to Vinyl Acetate Monomer through Inhalation
Loving_2021_Cells_10_ Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation
Lum_2021_ACS.Chem.Neurosci__ Protective Effect of Natural Products against Huntington's Disease: An Overview of Scientific Evidence and Understanding Their Mechanism of Action
Ma_2021_Biomed.Chromatogr__e5077 Dynamic changes in chemical compositions and anti-acetylcholinesterase activity associated with steaming process of stem-leaf saponins of Panax notoginseng
Mahe_2021_Environ.Res__110784 The countryside or the city: which environment is better for the honeybee?
Meek_2021_Toxicol.In.Vitro__105102 In vitro age-related differences in rats to organophosphates
Morlock_2021_Antioxidants.(Basel)_10_ Effect-Directed Profiling of Powdered Tea Extracts for Catechins, Theaflavins, Flavonols and Caffeine
Nalbantoglu_2021_Ideggyogy.Sz_74_33 Electrophysiological investigation for autonomic dysfunction in patients with myasthenia gravis: A prospective study
Nasso_2021_Pharmaceuticals.(Basel)_14_ Annurca Apple Polyphenol Extract Affects Acetyl- Cholinesterase and Mono-Amine Oxidase In Vitro Enzyme Activity
Nguyen_2021_Int.J.Mol.Sci_22_ Influence of Acetylcholine Esterase Inhibitors and Memantine, Clinically Approved for Alzheimer's Dementia Treatment, on Intestinal Properties of the Mouse
Poliseno_2021_Biomolecules_11_ Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents
Refaey_2021_Bioorg.Chem_108_104643 Bioactive constituents from Thunbergia erecta as potential anticholinesterase and anti-ageing agents: Experimental and in silico studies
Sahin_2021_J.Biomol.Struct.Dyn__1 Synthesis, characterization, molecular docking and in vitro screening of new metal complexes with coumarin Schiff base as anticholine esterase and antipancreatic cholesterol esterase agents
Turkez_2021_Biomolecules_11_ Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer's Disease
Vieira_2021_Ecotoxicol.Environ.Saf_211_111920 Embryonic zebrafish response to a commercial formulation of azoxystrobin at environmental concentrations
Wang_2021_J.Nanobiotechnology_19_31 Protein liposomes-mediated targeted acetylcholinesterase gene delivery for effective liver cancer therapy
Wang_2021_J.Food.Biochem__e13618 Protective effects of orally administered shark compound peptides from Chiloscyllium plagiosum against acute inflammation
Yang_2021_Clin.Neuropharmacol__ Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis With Peripheral Nerve Hyperexcitability: Case Report and Literature Review
Zhang_2021_Eur.J.Med.Chem_213_113154 Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer's disease
Zhao_2021_J.Enzyme.Inhib.Med.Chem_36_248 Production, purification and biochemical characterisation of a novel lipase from a newly identified lipolytic bacterium Staphylococcus caprae NCU S6
Zou_2021_Int.J.Biol.Macromol__ Novel sampangine derivatives as potent inhibitors of Cu(2+)-mediated amyloid-beta protein aggregation, oxidative stress and inflammation
Adewole_2021_In.Silico.Pharmacol_9_14 BACE1 and cholinesterase inhibitory activities of compounds from Cajanus cajan and Citrus reticulata: an in silico study
Akomolafe_2021_J.Food.Biochem__e13629 Diets supplemented with raw and roasted pumpkin (Cucurbita pepo L) seeds improved some biochemical parameters associated with erectile function in rats
Anita_2021_Psychoneuroendocrinology_126_105149 Serum soluble epoxide hydrolase related oxylipins and major depression in patients with type 2 diabetes
Aydin_2021_Arch.Pharm.(Weinheim)__e2000330 Synthesis of N-alkylated pyrazolo[3,4-d]pyrimidine analogs and evaluation of acetylcholinesterase and carbonic anhydrase inhibition properties
Bae_2021_Int.J.Syst.Evol.Microbiol__ Ferrimonas lipolytica sp. nov., a facultatively anaerobic bacterium isolated from seawater
Bao_2021_ChemMedChem__ Design, Synthesis, and Structure-Activity Relationship Study of Pyrazolones as Potent Inhibitors against Pancreatic Lipase
Beato_2021_J.Med.Chem__ beta-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer's Disease Therapy
Beg_2021_J.Biol.Chem__100332 ATGL activity regulates GLUT1-mediated glucose uptake and lactate production via TXNIP stability in adipocytes
Bektasevic_2021_Chem.Biodivers__ Comparative Study of Chemical Composition, Cholinesterase Inhibition and Antioxidant Potential of Mentha pulegium L. Essential Oil
Ben Hlima_2021_Mar.Drugs_19_ Molecular and Structural Characterizations of Lipases from Chlorella by Functional Genomics
Bonora_2021_J.Endocrinol.Invest__1 Disentangling conflicting evidence on DPP-4 inhibitors and outcomes of COVID-19: narrative review and meta-analysis
Brawman-Mintzer_2021_J.Neurotrauma__ Rivastigmine Transdermal Patch Treatment for Moderate to Severe Cognitive Impairment in Veterans with Traumatic Brain Injury (RiVET Study): A Randomized Clinical Trial
Bursal_2021_Biometals__ Transition metal complexes of a multidentate Schiff base ligand containing pyridine: synthesis, characterization, enzyme inhibitions, antioxidant properties, and molecular docking studies
Camporesi_2021_Acta.Neuropathol.Commun_9_19 Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers
Cheng_2021_J.Pharm.Sci__ Identification of key excipients for the solubilization and structural characterization of lipoprotein lipase, an enzyme for hydrolysis of triglyceride
Choudhary_2021_Ann.Lab.Med_41_129 Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19
Della Pietra_2021_Int.J.Mol.Sci_22_ Distinct Activity of Endocannabinoid-Hydrolyzing Enzymes MAGL and FAAH in Key Regions of Peripheral and Central Nervous System Implicated in Migraine
Ding_2021_ACS.Chem.Neurosci__ ((E)-N-(4-(((2-Amino-5-phenylpyridin-3-yl)imino)methyl)pyridin-2-yl)cyclopropanecarboxamide) Ameliorated Abeta(1-42)-Induced Alzheimer's Disease in SD Rats by Inhibiting Oxidative Stress and Apoptosis
Dong_2021_ACS.Appl.Mater.Interfaces__ Binding Peptide-Guided Immobilization of Lipases with Significantly Improved Catalytic Performance Using Escherichia coli BL21(DE3) Biofilms as a Platform
Dong_2021_World.J.Emerg.Med_12_24 Clinical correlates of hypotension in patients with acute organophosphorus poisoning
Ewen_2021_Life.Sci__119129 A review on advances of treatment modalities for Alzheimer's disease
Ghofrani_2021_Daru__ Immobilization of Candida rugosa lipase for resolution of racimic ibuprofen
Gianessi_2021_Eur.J.Neurosci__ The effects of fatty acid amide hydrolase inhibition and monacylglycerol lipase inhibition on habit formation in mice
Gurunathan_2021_Int.J.Nanomedicine_16_515 Platinum Nanoparticles Enhance Exosome Release in Human Lung Epithelial Adenocarcinoma Cancer Cells (A549): Oxidative Stress and the Ceramide Pathway are Key Players
Jan_2021_Int.J.Nanomedicine_16_443 Decrease in Cellular Nanovesicles Concentration in Blood of Athletes More Than 15 Hours After Marathon
Jonczyk_2021_Biomolecules_11_ Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase
Kadowaki_2021_Diabetes.Obes.Metab__ A Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adding Omarigliptin to Insulin Therapy in Japanese Patients with Type 2 Diabetes and Inadequate Glycemic Control
Karimi_2021_In.Silico.Pharmacol_9_13 In vitro cholinesterase inhibitory action of Cannabis sativa L. Cannabaceae and in silico study of its selected phytocompounds
Khamees_2021_Int.J.Clin.Pract__e14036 No Impact of Soluble Epoxide Hydrolase rs4149243, rs2234914 and rs751142 Genetic Variants on the Development of Type II Diabetes and its Hypertensive Complication among Jordanian Patients
Krams_2021_Int.J.Environ.Res.Public.Health_18_ The Obesity Paradox Predicts the Second Wave of COVID-19 to Be Severe in Western Countries
Krejner-Bienias_2021_Arch.Immunol.Ther.Exp.(Warsz)_69_1 DPP4 Inhibitors and COVID-19-Holy Grail or Another Dead End?
Kumar_2021_Life.Sci__119115 Pancreatic lipase inhibitors: The road voyaged and successes
Li_2021_Pestic.Biochem.Physiol_172_104769 Biogenetic cantharidin is a promising leading compound to manage insecticide resistance of Mythimna separata (Lepidoptera: Noctuidae)
Li_2021_Commun.Biol_4_144 Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
Liao_2021_Genes.(Basel)_12_ Functional Haplotype of LIPC Induces Triglyceride-Mediated Suppression of HDL-C Levels According to Genome-Wide Association Studies
Lopa_2021_Int.J.Food.Sci_2021_8862025 Phytochemical Analysis and Cholinesterase Inhibitory and Antioxidant Activities of Enhydra fluctuans Relevant in the Management of Alzheimer's Disease
Maupu_2021_Neurobiol.Dis__105276 Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice
Mitra_2021_Addict.Biol__e13007 A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence
Munir_2021_Molecules_26_ Microwave-Assisted Synthesis of (Piperidin-1-yl)quinolin-3-yl)methylene)hydrazinecarbothioamides as Potent Inhibitors of Cholinesterases: A Biochemical and In Silico Approach
Nguyen_2021_Colloids.Surf.B.Biointerfaces_200_111587 An acetylcholinesterase-based biosensor for the detection of pesticides using liquid crystals confined in microcapillaries
Obara_2021_Yakugaku.Zasshi_141_245 [Mechanism of the Long-lasting Potentiating Effect of Distigmine on Urinary Bladder Motility]
Oboh_2021_J.Ayurveda.Integr.Med__ Anticholinesterase activity and antioxidant properties of Heinsia crinita and Pterocarpus soyauxii in Drosophila melanogaster model
Park_2021_J.Microbiol.Biotechnol__ Skin commensal fungus Malassezia and its lipases
Pralle_2021_Sci.Rep_11_2839 Greater liver PNPLA3 protein abundance in vivo and in vitro supports lower triglyceride accumulation in dairy cows
Przygrodzka_2021_Endocrinology__ PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis
Qafary_2021_Int.J.Biol.Macromol_174_32 Urea titration of a lipase from Pseudomonas sp. reveals four different conformational states, with a stable partially folded state explaining its high aggregation propensity
Roussel_2021_Diabetes.Obes.Metab__ Use of Dipeptidyl Peptidase-4 inhibitors and prognosis of COVID-19 in hospitalized patients with type 2 diabetes: a propensity score analysis from the CORONADO study
Sharma_2021_Toxicol.Rep_8_223 Neuroprotective potential of hydroethanolic hull extract of Juglans regia L. on isoprenaline induced oxidative damage in brain of Wistar rats
Shukur_2021_Arch.Pharm.(Weinheim)__e2000467 Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease
Silva_2021_Bioorg.Chem_108_104649 7-Amine-spiro[chromeno[4,3-b]quinoline-6,1'-cycloalkanes]: Synthesis and cholinesterase inhibitory activity of structurally modified tacrines
Sivapalasingam_2021_J.Infect.Dis__ Human Monoclonal Antibody Cocktail for the Treatment or Prophylaxis of Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV)
Smith_2021_Acta.Biomater__ Organophosphate Detoxification by Membrane-Engineered Red Blood Cells
Tian_2021_Sheng.Wu.Gong.Cheng.Xue.Bao_37_88 [Propeptide-mediated protein folding: mechanism and its impact on lipase]
Urbanikova_2021_3.Biotech_11_84 CE16 acetylesterases: in silico analysis, catalytic machinery prediction and comparison with related SGNH hydrolases
Varshney_2021_Neuropeptides_86_102122 Ang (1-7)\/Mas receptor-axis activation promotes amyloid beta-induced altered mitochondrial bioenergetics in discrete brain regions of Alzheimer's disease-like rats
Wang_2021_Zhonghua.Nei.Ke.Za.Zhi_60_134 [Serum C-reactive protein, cholinesterase and prealbumin are correlated with prognosis of severe coronavirus disease 2019 patients]
Wang_2021_J.Pain.Res_14_61 Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence
Whitfield_2021_Twin.Res.Hum.Genet__1 Comparison of Familial, Polygenic and Biochemical Predictors of Mortality
Yan_2021_Genome.Biol.Evol__ A highly contiguous genome assembly of a polyphagous predatory mite Stratiolaelaps scimitus (Womersley) (Acari: Laelapidae)
Yang_2021_Mar.Drugs_19_ An In-Silico Comparative Study of Lipases from the Antarctic Psychrophilic Ciliate Euplotes focardii and the Mesophilic Congeneric Species Euplotes crassus: Insight into Molecular Cold-Adaptation
Zhang_2021_Colloids.Surf.B.Biointerfaces_200_111584 Neuroprotective effects of maize tetrapeptide-anchored gold nanoparticles in Alzheimer's disease
Zhang_2021_ACS.Sens__ Fluorescent Determination of Butyrylcholinesterase Activity and Its Application in Biological Imaging and Pesticide Residue Detection
Zou_2021_Open.Biol_11_200306 Alterations of the endocannabinoid system and its therapeutic potential in autism spectrum disorder
Monteiro_2021_Catal.Today_362_141 Biotechnological relevance of the lipase A from Candida antarctica
Barzkar_2021_Appl.Biochem.Biotechnol__ Marine Bacterial Esterases: Emerging Biocatalysts for Industrial Applications
Nunes_2021_Bioprocess.Biosyst.Eng__ Waste soybean frying oil for the production, extraction, and characterization of cell-wall-associated lipases from Yarrowia lipolytica
Aliomrani_2021_Neurotoxicol.Teratol__106957 -AChR is partly responsible in mice depressive-like behavior after Phosalone exposure
Amat-Ur-Rasool_2021_Brain.Sci_11_ Anti-Cholinesterase Combination Drug Therapy as a Potential Treatment for Alzheimer's Disease
Barmpa_2021_J.Inorg.Biochem_217_111357 Copper(II) complexes with meclofenamate ligands: Structure, interaction with DNA and albumins, antioxidant and anticholinergic activity
Bilal_2021_Int.J.Biol.Macromol__ Immobilized lipases-based nano-biocatalytic systems - A versatile platform with incredible biotechnological potential
Choquer_2021_Environ.Microbiol__ The infection cushion of Botrytis cinerea: a fungal weapon of plant-biomass destruction
English_2021_Sci.Rep_11_2914 Neonicotinoid pesticides exert metabolic effects on avian pollinators
Fan_2021_Structure__ Interplay between hevin, SPARC, and MDGAs: modulators of neurexin-neuroligin transsynaptic bridges
Gbadamosi_2021_Sci.Total.Environ_771_144752 A critical review of human exposure to organophosphate esters with a focus on dietary intake
Grott_2021_Sci.Total.Environ_771_144971 Influence of temperature on biomarker responses and histology of the liver of American bullfrog tadpoles (Lithobates catesbeianus, Shaw, 1802) exposed to the herbicide Tebuthiuron
Hayes_2021_Curr.Pharm.Des__ Bioactive peptides in preventative healthcare: An overview of bioactivities and suggested methods to assess potential applications
Hsiao_2021_Mayo.Clin.Proc_96_350 The Association Between the Use of Cholinesterase Inhibitors and Cardiovascular Events Among Older Patients With Alzheimer Disease
Hu_2021_J.Chem.Inf.Model__ Degradation of a Main Plastic Pollutant Polyethylene Terephthalate by Two Distinct Proteases (Neprilysin and Cutinase-like Enzyme)
Kanojia_2021_CNS.Neurol.Disord.Drug.Targets__ Beta-caryophyllene, a CB2R selective agonist, protects against cognitive impairment caused by neuro-inflammation and not in dementia due to ageing induced by mitochondrial dysfunction
Khadrawy_2021_Cardiovasc.Toxicol__ The Effect of Curcumin Nanoparticles on Cisplatin-Induced Cardiotoxicity in Male Wistar Albino Rats
Kim_2021_iScience_24_102037 Impaired formation of high-order gephyrin oligomers underlies gephyrin dysfunction-associated pathologies
Kim_2021_Medicine.(Baltimore)_100_e24040 Paradoxical pulmonary hemorrhage associated with hemocoagulase batroxobin in a patient with hemoptysis: A CARE-compliant case report
Kobzev_2021_Mol.Divers__ Synthesis of 8-phenyl substituted 3-benzazecines with allene moiety, their thermal rearrangement and evaluation as acetylcholinesterase inhibitors
Kratasyuk_2021_Sensors.(Basel)_21_ Software for Matching Standard Activity Enzyme Biosensors for Soil Pollution Analysis
Kumawat_2021_J.Phys.Chem.B__ Organoselenium Compounds as Acetylcholinesterase Inhibitors: Evidence and Mechanism of Mixed Inhibition
Li_2021_J.Asian.Nat.Prod.Res_24_88 Bisabolanoic acid A, a new polychiral sesquiterpene with AChE inhibitory activity from a mangrove-derived fungus Colletotrichum sp
Lirio_2021_Dalton.Trans_50_1866 Fast multipoint immobilization of lipase through chiral L-proline on a MOF as a chiral bioreactor
Loh_2021_J.Enzyme.Inhib.Med.Chem_36_627 New 3-O-substituted xanthone derivatives as promising acetylcholinesterase inhibitors
Magalhaes-Gomes_2021_Neurosci__ Increasead cholinergic tone causes pre-synaptic neuromuscular degeneration and is associated with impaired diaphragm function
Martins_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_252_119511 Impact on cholinesterase-inhibition and in silico investigations of sesquiterpenoids from Amazonian Siparuna guianensis Aubl
Maruszewska-Cheruiyot_2021_Parasit.Vectors_14_106 The production of excretory-secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures
McGregor_2021_J.Econ.Entomol_114_24 Comparison of the Effect of Insecticides on Bumble Bees (Bombus impatiens) and Mosquitoes (Aedes aegypti and Culex quinquefasciatus) by Standard Mosquito Research Methods
Miskovic_2021_J.Fungi.(Basel)_7_ Comparison of Two Schizophyllum commune Strains in Production of Acetylcholinesterase Inhibitors and Antioxidants from Submerged Cultivation
Mokhtar_2021_Int.J.Biol.Macromol__ Extraction and reimmobilization of used commercial lipase from industrial waste
Oboh_2021_J.Food.Biochem__e13616 Effect of citrus peels-supplemented diet on longevity, memory index, redox status, cholinergic and monoaminergic enzymes in Drosophila melanogaster model
Prakash_2021_Data.Brief_34_106721 Dataset of Swimming behavioral alterations in Danio rerio by Nemopilema nomurai jellyfish venom
Ramasamy_2021_Environ.Sci.Pollut.Res.Int__ Chemical characterization of billy goat weed extracts Ageratum conyzoides (Asteraceae) and their mosquitocidal activity against three blood-sucking pests and their non-toxicity against aquatic predators
Rani_2021_J.Basic.Clin.Physiol.Pharmacol__ Pharmacological investigations on efficacy of Phlorizin a sodium-glucose co-transporter (SGLT) inhibitor in mouse model of intracerebroventricular streptozotocin induced dementia of AD type
Rapichai_2021_Biotechnol.Lett__ MPH-GST sensing microplate for easy detection of organophosphate insecticides
Rodriguez-Salarichs_2021_J.Chem.Inf.Model__ Versatile Lipases from the Candida rugosa-like Family: A Mechanistic Insight Using Computational Approaches
Saber_2021_J.Enzyme.Inhib.Med.Chem_36_618 Phytochemical profile, enzyme inhibition activity and molecular docking analysis of Feijoa sellowiana O. Berg
Salau_2021_J.Food.Biochem__e13641 Ferulic acid promotes muscle glucose uptake and modulate dysregulated redox balance and metabolic pathways in ferric-induced pancreatic oxidative injury
Sinan_2021_Biomolecules_11_ Deeper Insights on Alchornea cordifolia (Schumach. & Thonn.) Mll.Arg Extracts: Chemical Profiles, Biological Abilities, Network Analysis and Molecular Docking
Soares_2021_Neurochem.Res__ The Protective Action of Rubus sp. Fruit Extract Against Oxidative Damage in Mice Exposed to Lipopolysaccharide
Syme_2021_PLoS.One_16_e0245804 Which indoor residual spraying insecticide best complements standard pyrethroid long-lasting insecticidal nets for improved control of pyrethroid resistant malaria vectors?
Takagi_2021_Surg.Today__ Clinical outcome of cardiac surgery in patients with remitted or active hepatocellular carcinoma
Tokali_2021_Arch.Pharm.(Weinheim)__e2000455 Design, synthesis, molecular docking, and some metabolic enzyme inhibition properties of novel quinazolinone derivatives
Wang_2021_Anal.Chem__ Fabrication of Bioresource-Derived Porous Carbon-Supported Iron as an Efficient Oxidase Mimic for Dual-Channel Biosensing
Wang_2021_Foods_10_ Perilla frutescens Leaf Extract and Fractions: Polyphenol Composition, Antioxidant, Enzymes (alpha-Glucosidase, Acetylcholinesterase, and Tyrosinase) Inhibitory, Anticancer, and Antidiabetic Activities
Yu_2021_J.Mater.Chem.B__ Butyrylcholinesterase nanodepots with enhanced prophylactic and therapeutic performance for acute organophosphorus poisoning management
Zhao_2021_Bioorg.Chem_108_104656 Multivalent butyrylcholinesterase inhibitor discovered by exploiting dynamic combinatorial chemistry
Zou_2021_J.Proteomics__104124 Use of data-independent acquisition mass spectrometry for comparative proteomics analyses of sera from pregnant women with intrahepatic cholestasis of pregnancy
Heier_2021_Elife_10_ Hormone-sensitive lipase couples intergenerational sterol metabolism to reproductive success
Vogel_2021_Microorganisms_9_ Comparative Genomics of Marine Bacteria from a Historically Defined Plastic Biodegradation Consortium with the Capacity to Biodegrade Polyhydroxyalkanoates
Ahmad_2021_Curr.Neuropharmacol__ Study of Nutraceuticals and Phytochemicals for the Management of Alzheimer's Disease: A Review
Alabbas_2021_BMC.Pediatr_21_72 Wolman's disease presenting with secondary hemophagocytic lymphohistiocytosis: a case report from Saudi Arabia and literature review
Altaf_2021_Hum.Exp.Toxicol__960327121993207 Cell membrane enveloped polymeric nanosponge for detoxification of chlorpyrifos poison: In vitro and in vivo studies
Banji_2021_Biomed.Res.Int_2021_6645720 Neuroprotective Effect of Turmeric Extract in Combination with Its Essential Oil and Enhanced Brain Bioavailability in an Animal Model
Bist_2021_Sci.Rep_11_3668 Defensive proclivity of bacoside A and bromelain against oxidative stress and AChE gene expression induced by dichlorvos in the brain of Mus musculus
Brinza_2021_Antioxidants.(Basel)_10_ Bay Leaf (Laurus Nobilis L.) Incense Improved Scopolamine-Induced Amnesic Rats by Restoring Cholinergic Dysfunction and Brain Antioxidant Status
Cagli_2021_Drug.Dev.Res__ Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome-related pro-inflammatory and anti-inflammatory signaling pathways in the lipopolysaccharide-induced pain mouse model
Chen_2021_J.Hazard.Mater_413_125306 Aggregation-induced emission luminogen@manganese dioxide core-shell nanomaterial-based paper analytical device for equipment-free and visual detection of organophosphorus pesticide
Cizkova_2021_Cells.Tissues.Organs__1 Soluble Epoxide Hydrolase as an Important Player in Intestinal Cell Differentiation
Cui_2021_Molecules_26_ Endophytic Fungal Community of Huperzia serrata: Diversity and Relevance to the Production of Huperzine A by the Plant Host
de Oliveira_2021_Chem.Biodivers__ Extraction Yield, Chemical Composition, Preliminary Toxicity of Bignonia nocturna (Barb.Rodr.) L.G. Lohmann (Bignoniaceae) Essential Oil and In silico evaluation of the interaction
Dolar_2021_Sci.Total.Environ_772_144900 Microplastics, chlorpyrifos and their mixtures modulate immune processes in the terrestrial crustacean Porcellio scaber
Elshamy_2021_J.Food.Biochem__e13644 Potential neuroprotective activity of Mentha longifolia L. in aluminum chloride-induced rat model of Alzheimer's disease
Erukainure_2021_Amino.Acids_53_359 Oxidative testicular injury: effect of L-leucine on redox, cholinergic and purinergic dysfunctions, and dysregulated metabolic pathways
Gallego_2021_Environ.Pollut_275_116647 Ecotoxicological impact of the antihypertensive valsartan on earthworms, extracellular enzymes and soil bacterial communities
Gbenga-Fabusiwa_2021_J.Food.Biochem__e13658 Modulatory effect of pigeon pea-wheat biscuits on lipid profile, lipid peroxidation level, alpha-glucosidase, and butyrylcholinesterase activities in type-2 diabetic patients
Guan_2021_Talanta_225_121948 Fluorometric probe for the lipase level: Design, mechanism and biological imaging application
Gutbrod_2021_Phytochemistry_185_112684 Fatty acid isoprenoid alcohol ester synthesis in fruits of the African Oil Palm (Elaeis guineensis)
Hafez_2021_Mol.Cell.Biochem__ Ameliorative effects of astaxanthin on brain tissues of alzheimer's disease-like model: cross talk between neuronal-specific microRNA-124 and related pathways
Handl_2021_Chem.Res.Toxicol__ Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening
Jamieson_2021_Int.J.Mol.Sci_22_ Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury
Junkum_2021_J.Med.Entomol__ Enhancement of Temephos and Deltamethrin Toxicity by Petroselinum crispum Oil and its Main Constituents Against Aedes aegypti (Diptera: Culicidae)
Kazakova_2021_Int.J.Mol.Sci_22_ Cytotoxic Potential of a-Azepano- and 3-Amino-3,4-SeCo-Triterpenoids
Kong_2021_Molecules_26_ Potential of Naturally Derived Alkaloids as Multi-Targeted Therapeutic Agents for Neurodegenerative Diseases
Kotake_2021_Intern.Med__ Cholinergic Crisis Owing to Distigmine Bromide Complicated by Hyperosmolar Hyperglycemic State
Kurach_2021_Int.J.Mol.Sci_22_ Mechanisms of the Procognitive Effects of Xanthotoxin and Umbelliferone on LPS-Induced Amnesia in Mice
Liu_2021_Cancer.Chemother.Pharmacol__ Carboxylesterase 1 polymorphisms are associated with clinical outcomes in gastroenteric cancer patients treated with capecitabine
Liu_2021_Food.Funct__ Phlorizin exerts potent effects against aging induced by D-galactose in mice and PC12 cells
Luo_2021_Front.Cell.Dev.Biol_8_620543 Non-neuronal Role of Acetylcholinesterase in Bone Development and Degeneration
Lyagin_2021_Int.J.Mol.Sci_22_ Enzymes, Reacting with Organophosphorus Compounds as Detoxifiers: Diversity and Functions
Mandic_2021_PLoS.One_16_e0246810 Chemical characterization and in vitro immunomodulatory effects of different extracts of moss Hedwigia ciliata (Hedw.) P. Beauv. from the Vrake Planine Mts., Serbia
Manzoor_2021_Eur.J.Med.Chem_215_113224 Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation
Montana_2021_Healthcare.(Basel)_9_ A Rare Case of Suicide by Ingestion of Phorate: A Case Report and a Review of the Literature
Negrya_2021_Mol.Biol.(Mosk)_55_164 [Glycol and Phosphate Depot Forms of 4- and\/or 5-Modified Nucleosides Exhibiting Antibacterial Activity]
Nichols_2021_Toxicology__152719 Reactivation of Organophosphate-inhibited Serum Butyrylcholinesterase by Novel Substituted Phenoxyalkyl Pyridinium Oximes and Traditional Oximes
Nishida_2021_Metabolomics_17_26 Whole-body insulin resistance and energy expenditure indices, serum lipids, and skeletal muscle metabolome in a state of lipoprotein lipase overexpression
Oda_2021_Methods.Enzymol_648_159 Cutinases from thermophilic bacteria (actinomycetes): From identification to functional and structural characterization
Pellegrini_2021_J.Clin.Endocrinol.Metab__ Generation of beta cells from iPSC of a MODY8 patient with a novel mutation in the carboxyl ester lipase (CEL) gene
Phaya_2021_Artif.Cells.Nanomed.Biotechnol_49_166 Oxidative biotransformation of stemofoline alkaloids
Phillips_2021_Int.J.Hyg.Environ.Health_233_113691 Acetylcholinesterase activity and thyroid hormone levels in Ecuadorian adolescents living in agricultural settings where organophosphate pesticides are used
Ribitsch_2021_Methods.Enzymol_648_293 Tuning of adsorption of enzymes to polymer
Saleem_2021_Metab.Brain.Dis_36_889 Neuroprotective potential of Malva neglecta is mediated via down-regulation of cholinesterase and modulation of oxidative stress markers
Sheedlo_2021_Biochemistry__ Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA
Shen_2021_ACS.Appl.Mater.Interfaces__ Detection of Carboxylesterase 1 and Chlorpyrifos with ZIF-8 Metal-Organic Frameworks Using a Red Emission BODIPY-Based Probe
Sheng_2021_J.Insect.Sci_21_ Evaluation of Sensitivity to Phoxim and Cypermethrin in an Endoparasitoid, Meteorus pulchricornis (Wesmael) (Hymenoptera: Braconidae), and Its Parasitization Efficiency Under Insecticide Stress
Shiba_2021_Eur.Heart.J.Acute.Cardiovasc.Care__ Serum cholinesterase as a prognostic biomarker for acute heart failure
Shimura_2021_BMC.Neurol_21_61 Rivastigmine improves dual-task gait velocity in patients with Alzheimer's disease
Shunan_2021_Biomed.Pharmacother_137_111369 Neuroprotective effect of Betalain against AlCl(3)-induced Alzheimer's disease in Sprague Dawley Rats via putative modulation of oxidative stress and nuclear factor kappa B (NF-kappaB) signaling pathway
Sine_2021_Arch.Environ.Occup.Health__1 Measuring butyrylcholinesterase activity and hematological parameters in farmers exposed to pesticides: a case and control study from Morocco
Song_2021_Oxid.Med.Cell.Longev_2021_8844455 Osthole-Loaded Nanoemulsion Enhances Brain Target in the Treatment of Alzheimer's Disease via Intranasal Administration
Thakur_2021_Med.Chem__ Synthesis, Molecular Docking, BSA, and in-vitro reactivation study of imidazopyridine oxime against paraoxon inhibited acetylcholinesterase
Thapa_2021_Bioorg.Chem_108_104681 Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer's disease
Tian_2021_Mini.Rev.Med.Chem__ Multi-target drug design of anti-Alzheimer's disease based on tacrine
Tiguman_2021_Rev.Paul.Pediatr_39_e2020130 AVAILABILITY AND STORAGE OF HAZARDOUS PRODUCTS IN HOUSEHOLDS IN THE METROPOLITAN REGION OF MANAUS: A POPULATION-BASED SURVEY, 2015
Valarezo_2021_Plants.(Basel)_10_ Study of Volatile Secondary Metabolites Present in Piper carpunya Leaves and in the Traditional Ecuadorian Beverage Guaviduca
Vanessa_2021_Mini.Rev.Med.Chem__ Xanthone: Potential Acetylcholinesterase Inhibitor for Alzheimer's Disease Treatment
Wang_2021_Int.J.Mol.Sci_22_1387 Identification, Classification, and Expression Analysis of the Triacylglycerol Lipase (TGL) Gene Family Related to Abiotic Stresses in Tomato
Wang_2021_Am.J.Sports.Med__363546520988680 The Enhancement Effect of Acetylcholine and Pyridostigmine on Bone-Tendon Interface Healing in a Murine Rotator Cuff Model
Wu_2021_Anal.Chem__ Two-Dimensional MnO(2) Nanozyme-Mediated Homogeneous Electrochemical Detection of Organophosphate Pesticides without the Interference of H(2)O(2) and Color
Zhang_2021_Biochem.Biophys.Res.Commun_546_111 Specific immobilization of lipase on functionalized 3D printing scaffolds via enhanced hydrophobic interaction for efficient resolution of racemic 1-indanol
Zhu_2021_Appl.Microbiol.Biotechnol__ Effect of cross-linked enzyme aggregate strategy on characterization of sn-1,3 extracellular lipase from Aspergillus niger GZUF36
Akocak_2021_Chem.Biodivers__ Synthesis, characterization, and inhibition study of novel substituted phenylureido sulfaguanidine derivatives as alpha-glycosidase and cholinesterase inhibitors
Al Hamoui Dit Banni_2021_Analyst_146_1386 Screening for pancreatic lipase natural modulators by capillary electrophoresis hyphenated to spectrophotometric and conductometric dual detection
Anastassiadou_2021_EFSA.J_19_e06392 Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides
Aslam_2021_Biomed.Res.Int_2021_6631042 Anti-5'-Nucleotidases (5'-ND) and Acetylcholinesterase (AChE) Activities of Medicinal Plants to Combat Echis carinatus Venom-Induced Toxicities
Attademo_2021_Environ.Sci.Pollut.Res.Int__ Effects of the emulsifiable herbicide Dicamba on amphibian tadpoles: an underestimated toxicity risk?
Baruah_2021_ACS.Pharmacol.Transl.Sci_4_193 Sulfonylurea Class of Antidiabetic Drugs Inhibit Acetylcholinesterase Activity: Unexplored Auxiliary Pharmacological Benefit toward Alzheimer's Disease
Bhardwaj_2021_Drug.Chem.Toxicol__1 Analysis of suppressive effects of pesticide triazophos on leucocyte immune responses in a teleost, Channa Punctatus
Biermann_2021_Angew.Chem.Int.Ed.Engl__ Fatty Acids and their Derivatives as Renewable Platform Molecules for the Chemical Industry
Boga_2021_J.Ethnopharmacol__113933 Volatile and Phenolic Profiling of a Traditional Medicinal Plant, Hypericum empetrifolium with in vitro Biological Activities
Centeno-Betanzos_2021_Chem.Biodivers__ Plants of the 'Libellus de Medicinalibus Indorum Herbis' from Mexico, 1552. Zephyranthes fosteri (Amaryllidaceae) Alkaloids
Chaves_2021_Curr.Med.Chem__ Recent Multi-Target Approaches on the Development of Anti-Alzheimer`s Agents Integrating Metal Chelation Activity
Chen_2021_Food.Chem_345_128560 Fluorescent and colorimetric dual-response sensor based on copper (II)-decorated graphitic carbon nitride nanosheets for detection of toxic organophosphorus
Chintalchere_2021_Proc.Natl.Acad.Sci.India.Sect.B.Biol.Sci__1 Bioefficacy of Lemongrass and Tea Tree Essential Oils Against House Fly, Musca domestica
Coors_2021_Environ.Toxicol.Chem__ Evidence for Specific Receptor-Mediated Toxicity of Pharmaceuticals in Aquatic Organisms Derived from Acute and Chronic Standard Endpoints
Das_2021_Neurotoxicol__ Dihydroactinidiolide regulates Nrf2\/HO-1 expression and inhibits caspase-3\/Bax pathway to protect SH-SY5Y human neuroblastoma cells from oxidative stress induced neuronal apoptosis
de Moraes Meine_2021_Int.J.Dev.Neurosci__ Acute hypermethioninemia impairs redox homeostasis and acetylcholinesterase activity in the hippocampus, striatum and cerebellum of young rats
Decarpigny_2021_Colloids.Surf.B.Biointerfaces_200_111606 Oxidation of 2,5-diformfylfuran to 2,5-furandicarboxylic acid catalyzed by Candida antarctica Lipase B immobilized in a cyclodextrin-templated mesoporous silica. The critical role of pore characteristics on the catalytic performance
Diez-Buitrago_2021_Talanta_225_122029 Development of portable CdS QDs screen-printed carbon electrode platform for electrochemiluminescence measurements and bioanalytical applications
Dominguez_2021_Neurotoxicol_84_30 Neurobehavioral and neurochemical effects in rats offspring co-exposed to arsenic and fluoride during development
Faria_2021_Sci.Total.Environ_775_145671 Androgenic activation, impairment of the monoaminergic system and altered behavior in zebrafish larvae exposed to environmental concentrations of fenitrothion
Gao_2021_Clin.Lab_67_ The Role of Cholinesterase in Differential Diagnosis between Gastric Cancer and Benign Gastric Diseases
Ha_2021_Curr.Alzheimer.Res__ Synthesis, Molecular Docking, and Biological Evaluation of Benzimidazole Derivatives as Selective Butyrylcholinesterase Inhibitors
Kaur_2021_Toxicol.Res.(Camb)_10_40 Neuroprotective effect of nerolidol in traumatic brain injury associated behavioural comorbidities in rats
Kong_2021_Mol.Psychiatry__ Reducing alcohol and\/or cocaine-induced reward and toxicity via an epidermal stem cell-based gene delivery platform
Lauwers_2021_Osteoarthritis.Cartilage__ The cholinergic system in joint health and osteoarthritis: a narrative-review
Liu_2021_Plant.Foods.Hum.Nutr_76_105 Chemical Constituents and their Antioxidant, Anti-Inflammatory and Anti-Acetylcholinesterase Activities from Pholidota cantonensis
Maleki_2021_Bioorg.Chem_109_104684 Design and synthesis of new carbamates as inhibitors for fatty acid amide hydrolase and cholinesterases: Molecular dynamic, in vitro and in vivo studies
Martinez-Alvarez_2021_Sci.Total.Environ_775_145669 Uptake and effects of graphene oxide nanomaterials alone and in combination with polycyclic aromatic hydrocarbons in zebrafish
Mooko_2021_Endocr.Metab.Immune.Disord.Drug.Targets__ Cannabis Sativa L. Flower and Bud Extracts inhibited In vitro Cholinesterases and b-Secretase Enzymes Activities: Possible Mechanisms of Cannabis use in Alzheimer Disease
Muniz-Gonzalez_2021_Environ.Sci.Pollut.Res.Int__ Persistent pesticides: effects of endosulfan at the molecular level on the aquatic invertebrate Chironomus riparius
Nazir_2021_BMC.Complement.Med.Ther_21_73 Chemical composition, in vitro antioxidant, anticholinesterase, and antidiabetic potential of essential oil of Elaeagnus umbellata Thunb
Parrish_2021_Sci.Rep_11_3218 Resolving whether inhalation of depleted uranium contributed to Gulf War Illness using high-sensitivity mass spectrometry
Pavlidis_2021_J.Inorg.Biochem_217_111393 Synthesis, characterization and pharmacological evaluation of quinoline derivatives and their complexes with copper() in in vitro cell models of Alzheimer's disease
Prabu_2021_Fish.Physiol.Biochem__ Antioxidant defence system based oxidative stress mitigation through dietary jamun tree leaf in experimentally infected snubnose pompano, Trachinotus blochii
Rai_2021_Biomed.Pharmacother_137_111377 Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases
Ren_2021_Biol.Trace.Elem.Res__ Effect of Selenium on Brain Injury in Chickens with Subacute Arsenic Poisoning
Rios_2021_Environ.Sci.Pollut.Res.Int__ Impact of dietary lipid level on esterase enzyme activities in the non-target freshwater shrimp Macrobrachium borellii exposed to chlorpyrifos
Robichaud_2021_Autophagy__ Identification of Novel Lipid Droplet Factors that Regulate Lipophagy and Cholesterol Efflux in Macrophage Foam Cells
Saw_2021_Cardiovasc.Diabetol_20_50 Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications
Sharmeen_2021_Chem.Biodivers__ GC\/MS Profiling, In Vitro and In Silico Pharmacological Screening and Principal Component Analysis of Essential Oils from Three Exotic and Two Endemic Plants from Mauritius
Vohra_2021_Br.J.Clin.Pharmacol__ Impact of deprivation, dementia prevalence and regional demography on prescribing of anti-dementia drugs in England: a time trend analysis
Wei_2021_Eur.J.Med.Chem_215_113286 Molecular modeling-guided optimization of acetylcholinesterase reactivators: A proof for reactivation of covalently inhibited targets
Wu_2021_Eur.J.Neurosci__ Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice
Xie_2021_Bioorg.Chem_109_104710 Synthesis and biological evaluation of novel 8- substituted sampangine derivatives as potent inhibitor of Zn(2+)-Abeta complex mediated toxicity, oxidative stress and inflammation
Xiong_2021_Nutrition_86_111155 Vitamins A and D fail to protect against tuberculosis-drug-induced liver injury: A post hoc analysis of a previous randomized controlled trial
Yang_2021_Eur.J.Pharmacol__173950 A review on alpha-mangostin as a potential multi-target-directed ligand for Alzheimer's disease
Yasuno_2021_Int.J.Geriatr.Psychiatry__ Significant effects of cholinesterase inhibitors on tau pathology in the Alzheimer's disease continuum: An in vivo positron emission tomography study
Yin_2021_J.Cell.Mol.Med__ Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway
Yokokawa_2021_Eur.J.Drug.Metab.Pharmacokinet__ Effect of UGT1A1, CYP3A and CES Activities on the Pharmacokinetics of Irinotecan and its Metabolites in Patients with UGT1A1 Gene Polymorphisms
Zhou_2021_Biomarkers__1 Cholinesterase homozygous genotype as susceptible biomarker of hypertriglyceridemia for pesticide-exposed agricultural workers
Arya_2021_Plant.Physiol.Biochem_161_234 Brassica juncea leaf cuticle proteome analysis shows myrosinase protein, antifreeze activity, and post-translationally modified secretory proteins
Butcherine_2021_Chemosphere_275_129918 Acute toxicity, accumulation and sublethal effects of four neonicotinoids on juvenile Black Tiger Shrimp (Penaeus monodon)
Casey_2021_J.Lipid.Res__100049 Lipid droplet membrane proteome remodeling parallels ethanol-induced hepatic steatosis and its resolution
Cerqueira_2021_J.Biomol.Struct.Dyn__1 Homology modeling, docking, molecular dynamics and in vitro studies to identify Rhipicephalus microplus acetylcholinesterase inhibitors
Delerue_2021_Food.Res.Int_140_109857 Interactions between Ginkgo biloba L. and Scutellaria baicalensis Georgi in multicomponent mixtures towards cholinesterase inhibition and ROS scavenging
Fakhar_2021_J.Biomol.Struct.Dyn__1 Discovery of novel heterocyclic amide-based inhibitors: an integrative in-silico approach to targeting soluble epoxide hydrolase
Falfushynska_2021_Water.Res_194_116923 Multibiomarker-based assessment of toxicity of central European strains of filamentous cyanobacteria Aphanizomenon gracile and Raphidiopsis raciborskii to zebrafish Danio rerio
Fang_2021_Int.J.Pharm__120399 Repurposing of Camptothecin: An Esterase-Activatable Prodrug Delivered by a Self-Emulsifying Formulation that Improves Efficacy in Colorectal Cancer
Fawzi_2021_Food.Res.Int_140_110068 A comprehensive evaluation of the chemical profiles and biological properties of six geophytes from Turkey: Sources of bioactive compounds for novel nutraceuticals
Ge_2021_Life.Sci__119268 Short-term standard alcohol consumption enhances platelet response to clopidogrel through inhibition of Nrf2\/Ces1 pathway and induction of Cyp2c in mice
Halff_2021_Behav.Brain.Res__113203 Effects of chronic exposure to haloperidol, olanzapine or lithium on SV2A and NLGN synaptic puncta in the rat frontal cortex
Huang_2021_J.Sep.Sci__ Fast analysis of alkaloids from different parts of Mahonia bealei (Fort.) Carr studied for their anti-Alzheimer's activity using supercritical fluid chromatography
Ilijin_2021_J.Therm.Biol_96_102836 Tissue-specific responses of Lymantria dispar L. (Lepidoptera: Erebidae) larvae from unpolluted and polluted forests to thermal stress
Jabir_2021_Curr.Pharm.Des__ Identification of butyrylcholinesterase and monoamine oxidase B targeted ligands and their putative application in Alzheimer's treatment: A computational strategy
Knysh_2021_Bull.Environ.Contam.Toxicol__ The Differential Effects of Salinity Level on Chlorpyrifos and Imidacloprid Toxicity to an Estuarine Amphipod
Lisboa_2021_Ecotoxicol.Environ.Saf_214_112049 Ecotoxicological responses of Eisenia andrei exposed in field-contaminated soils by sanitary sewage
Meads_2021_Toxicol.Appl.Pharmacol__115466 Evaluation of adenosine A1 receptor agonists as neuroprotective countermeasures against Soman intoxication in rats
Noori_2021_Eur.J.Pharmacol__173974 Role of Natural Products for the Treatment of Alzheimer's Disease
Oliveira_2021_Org.Biomol.Chem__ Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors
Omwenga_2021_Arch.Toxicol__ Prediction of dose-dependent in vivo acetylcholinesterase inhibition by profenofos in rats and humans using physiologically based kinetic (PBK) modeling-facilitated reverse dosimetry
Papadopoulos_2021_Neurol.India_69_177 The Relevance of Blepharoptosis in Diagnostic Suspicion of Myopathies
Perumal_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109021 Mitigation of arsenic induced developmental cardiotoxicity by ferulic acid in zebrafish
Pinz_2021_Metab.Brain.Dis__ Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na(+)\/K(+)-ATPase in an Alzheimer's disease model
Pruthi_2021_Metab.Brain.Dis__ Improvement of cognitive function in mice by Citrus reticulata var. kinnow via modulation of central cholinergic system and oxidative stress
Ramesh_2021_Curr.Biol__ Antagonistic interactions between two Neuroligins coordinate pre- and postsynaptic assembly
Saquib_2021_J.Appl.Toxicol__ Carbofuran cytotoxicity, DNA damage, oxidative stress, and cell death in human umbilical vein endothelial cells: Evidence of vascular toxicity
Srivastava_2021_Eur.J.Med.Chem_216_113320 Alzheimer's disease and its treatment by different approaches: A review
Taylor_2021_J.Neurochem__ Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical
Watt_2021_BMC.Med.Res.Methodol_21_41 Using a distribution-based approach and systematic review methods to derive minimum clinically important differences
Winek_2021_J.Neurochem__ Regulators of cholinergic signaling in disorders of the central nervous system
Yang_2021_Chemosphere_275_129974 Influence of suspended sediment on the bioavailability of benzophenone-3: Focus on accumulation and multi-biological effects in Daphnia magna
Yang_2021_J.Agric.Food.Chem__ pH-Response Quantum Dots with Orange-Red Emission for Monitoring the Residue, Distribution, and Variation of an Organophosphorus Pesticide in an Agricultural Crop
Zhang_2021_Environ.Pollut_277_116767 Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota
Zhang_2021_Zhongguo.Zhong.Yao.Za.Zhi_46_638 [Construction and application of pharmacophore model of human carboxylesterase 2 inhibitors]
Denlinger_2021_Evol.Appl_14_1248 Standing genetic variation in laboratory populations of insecticide-susceptible Phlebotomus papatasi and Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae) for the evolution of resistance
Abd_2021_Molecules_26_ Essential Oils as a Potential Neuroprotective Remedy for Age-Related Neurodegenerative Diseases: A Review
Arya_2021_Biomolecules_11_ Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer's Disease Therapy
Bezerra_2021_Clin.Nutr__ Do implant-supported prostheses affect bioavailability of nutrients of complete and partially edentulous patients? A systematic review with meta-analysis
Dahleh_2021_Free.Radic.Res__1 Exercise associated with gamma-oryzanol supplementation suppresses oxidative stress and prevents changes in locomotion in Drosophila melanogaster
Dall'Acqua_2021_Chem.Biodivers__ Phytochemical investigations and in vitro bioactivity screening on Melia azedarach L. leaves extract from Nepal
Ehiguese_2021_Environ.Res__110960 Galaxolide and tonalide modulate neuroendocrine activity in marine species from two taxonomic groups
Elmorsy_2021_Heliyon_7_e06269 The protective effect of Indian Catechu methanolic extract against aluminum chloride-induced neurotoxicity, A rodent model of Alzheimer's disease
Erdogan_2021_Arch.Pharm.(Weinheim)__e2000409 Synthesis and docking calculations of tetrafluoronaphthalene derivatives and their inhibition profiles against some metabolic enzymes
Gong_2021_Mol.Divers__ A novel artificial intelligence protocol to investigate potential leads for diabetes mellitus
Guimaraes_2021_Aquat.Toxicol_233_105795 Can carbon nanofibers affect anurofauna? Study involving neotropical Physalaemus cuvieri (Fitzinger, 1826) tadpoles
Guo_2021_Sci.Rep_11_5428 Bioinformatis analysis reveals possible molecular mechanism of PXR on regulating ulcerative colitis
Gupta_2021_Biochem.J__ Rivastigmine attenuates the Alzheimer's disease related protein degradation and apoptotic neuronal death signaling
Hamoudi_2021_Comb.Chem.High.Throughput.Screen__ Phytochemical screening, in vitro antioxidant and enzyme inhibitory proprieties and acute toxicity of extracts from the aerial parts of Ephedra nebrodensis, source of bioactive compounds
He_2021_J.Mater.Chem.B__ Near-infrared fluorescent probe for evaluating the acetylcholinesterase effect in the aging process and dietary restriction via fluorescence imaging
Hou_2021_Materials.(Basel)_14_ Potential for and Distribution of Enzymatic Biodegradation of Polystyrene by Environmental Microorganisms
Jasiecki_2021_Int.J.Mol.Sci_22_2 The Role of Butyrylcholinesterase and Iron in the Regulation of Cholinergic Network and Cognitive Dysfunction in Alzheimer's Disease Pathogenesis
Jin_2021_ACS.Chem.Biol__ The Angiopoietin-Like Protein 3 and 8 Complex Interacts with Lipoprotein Lipase and Induces LPL Cleavage
Kratky_2021_Molecules_26_ Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase
Liang_2021_J.Environ.Sci.Health.B__1 Insecticidal and acetylcholine esterase inhibition activity of Rhododendron thymifolium essential oil and its main constituent against two stored product insects
Mahomoodally_2021_Antibiotics.(Basel)_10_ Pharmacological Potential and Chemical Characterization of Bridelia ferruginea Benth.-A Native Tropical African Medicinal Plant
Marikova_2021_Molecules_26_ Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids
Marrero-Rosado_2021_Int.J.Mol.Sci_22_ Novel Genetically Modified Mouse Model to Assess Soman-Induced Toxicity and Medical Countermeasure Efficacy: Human Acetylcholinesterase Knock-in Serum Carboxylesterase Knockout Mice
Menghini_2021_Biomolecules_11_ Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil
Mohammed_2021_Life.Sci_273_119303 Electrophysiological and neurochemical evaluation of the adverse effects of REM sleep deprivation and epileptic seizures on rat's brain
Muley_2021_Bioprocess.Biosyst.Eng__ Preparation of cross-linked enzyme aggregates of lipase from Aspergillus niger: process optimization, characterization, stability, and application for epoxidation of lemongrass oil
Nazir_2021_Brain.Sci_11_ Phytochemical Analysis, In Vitro Anticholinesterase, Antioxidant Activity and In Vivo Nootropic Effect of Ferula ammoniacum (Dorema ammoniacum) D. Don. in Scopolamine-Induced Memory Impairment in Mice
Noazira_2021_Pak.J.Biol.Sci_24_13 Effect of Cymbopogon citratus Essential Oil (EO) on Handling Stress in Giant Freshwater Prawn (Macrobrachium rosenbergii)
Park_2021_Mar.Drugs_19_ Ecklonia cava Attenuates PM(2.5)-Induced Cognitive Decline through Mitochondrial Activation and Anti-Inflammatory Effect
Prakashkumar_2021_Pharmaceutics_13_ Decoding the Neuroprotective Potential of Methyl Gallate-Loaded Starch Nanoparticles against Beta Amyloid-Induced Oxidative Stress-Mediated Apoptosis: An In Vitro Study
Roberts_2021_Sci.Immunol_6_ Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths
Shaikh_2021_Bioorg.Chem_110_104770 Design, synthesis and evaluation of dihydropyranoindole derivatives as potential cholinesterase inhibitors against Alzheimer's disease
Singh_2021_Eur.J.Med.Chem_215_113278 A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease
Sun_2021_Front.Behav.Neurosci_15_594907 Melamine Disrupts Acetylcholine-Mediated Neural Information Flow in the Hippocampal CA3-CA1 Pathway
Valle-Martos_2021_Front.Pediatr_9_629346 Liver Enzymes Correlate With Metabolic Syndrome, Inflammation, and Endothelial Dysfunction in Prepubertal Children With Obesity
Van Overloop_2021_Geriatr.Psychol.Neuropsychiatr.Vieil__ Changes in psychotropic drug use among patients in the cognitive behavioural care unit in Toulon
Vinuela_2021_J.Alzheimers.Dis__ Assessment of a Potential Synergistic Effect of Souvenaid in Mild Alzheimer's Disease Patients on Treatment with Acetylcholinesterase Inhibitors: An Observational, Non-Interventional Study
Wannasaksri_2021_Molecules_26_ In Vitro Phytotherapeutic Properties of Aqueous Extracted Adenia viridiflora Craib. towards Civilization Diseases
Wong_2021_Neuropsychopharmacology__ Autistic-like behavior, spontaneous seizures, and increased neuronal excitability in a Scn8a mouse model
Youn_2021_Psychiatry.Investig__ The Behavioral Effects of Combination Therapy of Memantine and Acetylcholinesterase Inhibitors Compared with Acetylcholinesterase Inhibitors Alone in Patients with Moderate Alzheimer's Dementia: A Double-Blind Randomized Placebo-Controlled Trial
Zahoor_2021_Heliyon_7_e06367 Pharmacological evaluation and in-silico modeling study of compounds isolated from Ziziphus oxyphylla
Zang_2021_Molecules_26_ Claulansine F-Donepezil Hybrids as Anti-Alzheimer's Disease Agents with Cholinergic, Free-Radical Scavenging, and Neuroprotective Activities
Zhang_2021_Biotechnol.Appl.Biochem__ A stable biosensor based on chitosan-modified graphene for detecting organophosphorus pesticides
Abdpour_2021_Bioorg.Chem_110_104750 Chromone derivatives bearing pyridinium moiety as multi-target-directed ligands against Alzheimer's disease
Abolins_2021_Materials.(Basel)_14_ Impact of Different Epoxidation Approaches of Tall Oil Fatty Acids on Rigid Polyurethane Foam Thermal Insulation
Adole_2021_Anal.Biochem__114158 Clinical utility of validated gas chromatography-ion trap mass spectrometry in patients with anticholinesterase pesticides poisoning
Aguera-Ortiz_2021_Front.Psychiatry_12_638651 Depression in Alzheimer's Disease: A Delphi Consensus on Etiology, Risk Factors, and Clinical Management
Bansal_2021_Climacteric__1 Selective ER-beta agonists alleviate neuronal deficits in insulin-resistant estrogen-deficient rats
Battle_2021_Cochrane.Database.Syst.Rev_2_CD013306 Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta-analysis
Benitez_2021_Front.Endocrinol.(Lausanne)_12_636600 Nerve Growth Factor: A Dual Activator of Noradrenergic and Cholinergic Systems of the Rat Ovary
Chen_2021_Nutr.Neurosci__1 Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-alpha\/NF-kappaB\/caspase-3 signaling in type 2 diabetes rats
Dai_2021_J.Neurosurg.Sci__ Preliminary study of the consciousness-promotion mechanism of electroacupuncture in comatose patients with diffuse axonal injuries
Dellali_2021_Environ.Sci.Pollut.Res.Int_28_36523 Acute toxicity and biomarker responses in Gammarus locusta amphipods exposed to copper, cadmium, and the organochlorine insecticide dieldrin
Farouk_2021_Biomed.Pharmacother_138_111458 Exploring the possible neuroprotective and antioxidant potency of lycopene against acrylamide-induced neurotoxicity in rats' brain
Fernandes_2021_Chem.Biol.Interact__109431 Exposure to lutein-loaded nanoparticles attenuates Parkinson's model-induced damage in Drosophila melanogaster: restoration of dopaminergic and cholinergic system and oxidative stress indicators
Guzel_2021_J.Biochem.Mol.Toxicol__e22765 Biologically active phthalocyanine metal complexes: Preparation, evaluation of alpha-glycosidase and anticholinesterase enzyme inhibition activities, and molecular docking studies
Khurana_2021_Neurotox.Res__ Lacidipine Prevents Scopolamine-Induced Memory Impairment by Reducing Brain Oxido-nitrosative Stress in Mice
Meek_2021_Toxicol.Sci__ Inhibition Kinetics of 16 Organophosphorus Pesticides or Their Active Metabolites on Erythrocyte Acetylcholinesterase from Humans and Rats
Mourad_2021_Pharmaceuticals.(Basel)_14_ Novel Potent and Selective DPP-4 Inhibitors: Design, Synthesis and Molecular Docking Study of Dihydropyrimidine Phthalimide Hybrids
Nguyen_2021_Adv.Exp.Med.Biol_1286_183 Therapeutic Strategies and Nano-Drug Delivery Applications in Management of Aging Alzheimer's Disease
Olofinnade_2021_Cent.Nerv.Syst.Agents.Med.Chem__ Concentration-dependent effects of dietary L-ascorbic acid fortification in the brain of healthy mice
Park_2021_PLoS.One_16_e0248395 Association between dementia and systemic rheumatic disease: A nationwide population-based study
Patra_2021_Nanotechnology_32_235101 Nanonization of a chemically synthesized flavone HMDF (3-hydroxy-3',4'-methylenedioxyflavone) by entrapping within calcium phosphate nanoparticles and exploring its antioxidant role on neural cells in vitro and zebrafish in vivo
Schumacher_2021_Neuroimage.Clin_30_102604 In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies
Sebastian_2021_Physiol.Genomics__ The role of resistance to inhibitors of cholinesterase 8b in the control of heart rate
Shi_2021_J.Zhejiang.Univ.Sci.B_22_204 Expression of Drosophila melanogaster acetylcholinesterase (DmAChE) gene splice variants in Pichia pastoris and evaluation of its sensitivity to organophosphorus pesticides
Tuncsoy_2021_Environ.Sci.Pollut.Res.Int__ Influence of titanium dioxide nanoparticles on bioaccumulation, antioxidant defense and immune system of Galleria mellonella L
Wang_2021_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_39_147 [A case of death caused by fenitrothion poisoning]
Yagishita-Kyo_2021_Biochem.Biophys.Res.Commun_551_54 Testosterone interrupts binding of Neurexin and Neuroligin that are expressed in a highly socialized rodent, Octodon degus
Yang_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1170_122599 Rapid screening for natural lipase inhibitors from Alisma orientale combining high-performance thin-layer chromatography-bioautography with mass spectrometry
Yu_2021_Ann.Transl.Med_9_332 Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma
Zameer_2021_J.Appl.Toxicol__ Alendronate reduces the cognitive and neurological disturbances induced by combined doses of d-galactose and aluminum chloride in mice
Zhang_2021_Bioorg.Chem_110_104783 Paeonone A, a novel nonanortriterpenoid from the roots of Paeonia lactiflora
Zhao_2021_Arch.Toxicol__ Physiologically based kinetic modelling based prediction of in vivo rat and human acetylcholinesterase (AChE) inhibition upon exposure to diazinon
Adeel_2021_J.Hazard.Mater_415_125574 Bio-interaction of nano and bulk lanthanum and ytterbium oxides in soil system: Biochemical, genetic, and histopathological effects on Eisenia fetida
Almeida_2021_Environ.Toxicol.Pharmacol__103634 Can the insecticide imidacloprid affect the health of the Neotropical freshwater fish Astyanax altiparanae (Teleostei: Characidae)?
Badalamenti_2021_J.Ethnopharmacol__114050 The ethnobotany, phytochemistry and biological properties of genus Ferulago - A review
Baine_2021_J.Cell.Mol.Med__ Pyridostigmine improves cardiac function and rhythmicity through RyR2 stabilization and inhibition of STIM1-mediated calcium entry in heart failure
Bhavya_2021_J.Food.Sci.Technol_58_1611 Efficacy of Ocimum tenuiflorum essential oil as grain protectant against coleopteran beetle, infesting stored pulses
Chen_2021_Phytochemistry_186_112730 Pyrrolyl 4-quinolone alkaloids from the mangrove endophytic fungus Penicillium steckii SCSIO 41025: Chiral resolution, configurational assignment, and enzyme inhibitory activities
Cheng_2021_Sci.Total.Environ_768_144945 Insights into mechanisms involved in the uptake, translocation, and metabolism of phthalate esters in Chinese cabbage (Brassica rapa var. chinensis)
Chiang_2021_J.Gen.Physiol_153_ Recordings from neuron-HEK cell cocultures reveal the determinants of miniature excitatory postsynaptic currents
da Silva_2021_Neurochem.Res__ Multitarget Effect of 2-(4-(Methylthio)phenyl)-3-(3-(piperidin-1-yl)propyl)thiazolidin-4-one in a Scopolamine-Induced Amnesic Rat Model
Esmaeilnejad_2021_Trop.Anim.Health.Prod_53_219 Assessment of hepatic oxidative damage, paraoxonase-1 activity, and lipid profile in cattle naturally infected with Ba7besia bigemina
Fan_2021_Gigascience_10_ A chromosome-level genome of the spider Trichonephila antipodiana reveals the genetic basis of its polyphagy and evidence of an ancient whole-genome duplication event
Gan_2021_Exp.Ther.Med_21_425 Kuwanon G protects HT22 cells from advanced glycation end product-induced damage
Gok_2021_Arch.Pharm.(Weinheim)__e2000496 Synthesis of novel sulfonamides with anti-Alzheimer and antioxidant capacities
Honda_2021_Biochimie__ The involvement of Nile tilapia (Oreochromis niloticus) Neu4 sialidase in neural differentiation during early ontogenesis
Huang_2021_Nutr.Metab.Cardiovasc.Dis_31_681 ABHD15 promotes cell viability, glycolysis, and inhibits apoptosis in cardiomyocytes under hypoxia
Joviano-Santos_2021_FEBS.J__ Motoneuron-specific loss of VAChT mimics neuromuscular defects seen in Congenital Myasthenic Syndrome
Keck_2021_Cell.Mol.Gastroenterol.Hepatol__ Lack of mucosal cholinergic innervation is associated with increased risk of enterocolitis in Hirschsprung's disease
Kim_2021_Cell.Death.Differ__ Hevin-calcyon interaction promotes synaptic reorganization after brain injury
Kim_2021_Food.Sci.Biotechnol_30_287 Neuroprotective effects of ethanolic extract from dry Rhodiola rosea L. rhizomes
Komali_2021_J.Tradit.Complement.Med_11_137 Antiepileptic potential of Bacopa monnieri in the rat brain during PTZ-induced epilepsy with reference to cholinergic system and ATPases
Kuwahata_2021_Circ.Rep_3_115 Effect of QT Prolongation in Patients Taking Cholinesterase Inhibitors (Donepezil) for Alzheimer's Disease
Lane_2021_BMC.Fam.Pract_22_51 Primary care physician volume and quality of care for older adults with dementia: a retrospective cohort study
Limonta_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109037 Effects of microplastics on head kidney gene expression and enzymatic biomarkers in adult zebrafish
Lobine_2021_Chem.Biodivers__ Chemical Composition and Pharmacological Evaluation and of Toddalia asiatica (Rutaceae) Extracts and Essential Oil by in Vitro and in Silico Approaches
Mathew_2021_Environ.Sci.Pollut.Res.Int__1 Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders
Matzner_2021_J.Neurochem__ Rhythmogenic networks are potently modulated by activation of muscarinic acetylcholine receptors in the rodent spinal cord
Medvedev_2021_J.Mol.Biol_433_166788 A Fifth of the Protein World: Rossmann-like Proteins as an Evolutionarily Successful Structural unit
Mohammadi_2021_Comp.Immunol.Microbiol.Infect.Dis_76_101642 Evaluation of some acute phase proteins in cattle naturally infected with Babesia bigemina
Nilin_2021_Mar.Pollut.Bull_166_112233 Biological responses of mangrove oysters (Crassostrea rhizophorae) and mercury contamination in an urban tropical estuary
Obringer_2021_Regul.Toxicol.Pharmacol__104918 Effect of chain length and branching on the in vitro metabolism of a series of parabens in human liver S9, human skin S9, and human plasma
Park_2021_Food.Chem_353_129459 Erythorbyl fatty acid ester as a multi-functional food emulsifier: Enzymatic synthesis, chemical identification, and functional characterization of erythorbyl myristate
Poetini_2021_Dev.Biol_475_80 Iron overload during the embryonic period develops hyperactive like behavior and dysregulation of biogenic amines in Drosophila melanogaster
Pomara_2021_J.Affect.Disord_286_275 Evidence of upregulation of the cholinergic anti-inflammatory pathway in late-life depression
Qian_2021_Parasit.Vectors_14_169 A survey of insecticide resistance-conferring mutations in multiple targets in Anopheles sinensis populations across Sichuan, China
Quesada_2021_Environ.Toxicol.Chem__ Early Toxic Effects in a Central American Native Fish (Parachromis dovii) Exposed to Chlorpyrifos and Difenoconazole
Rodrigues_2021_Psychopharmacology.(Berl)__ The neurotherapeutic role of a selenium-functionalized quinoline in hypothalamic obese rats
Samad_2021_Biol.Trace.Elem.Res__ Inhibitory Effects of Selenium on Arsenic-Induced Anxiety-\/Depression-Like Behavior and Memory Impairment
Singh_2021_ACS.Omega_6_7165 Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain
Suarez-Lopez_2021_Expo.Health_13_51 Associations of acetylcholinesterase inhibition between pesticide spray seasons with depression and anxiety symptoms in adolescents, and the role of sex and adrenal hormones on gender moderation
Wakisaka_2021_Cerebrovasc.Dis__1 Pre-Stroke Cholinesterase Inhibitor Treatment Is Beneficially Associated with Functional Outcome in Patients with Acute Ischemic Stroke and Pre-Stroke Dementia: The Fukuoka Stroke Registry
Wang_2021_Front.Pharmacol_12_615104 Ultrasound Combined With Microbubbles Loading BDNF Retrovirus to Open BloodBrain Barrier for Treatment of Alzheimer's Disease
Wopara_2021_Heliyon_7_e06378 Anxiogenic and memory impairment effect of food color exposure: upregulation of oxido-neuroinflammatory markers and acetyl-cholinestrase activity in the prefrontal cortex and hippocampus
Xu_2021_Neurology__ Long Term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Zengin_2021_J.Pharm.Biomed.Anal_198_114018 Chemical composition, biological properties and bioinformatics analysis of two Caesalpina species: A new light in the road from nature to pharmacy shelf
Zhao_2021_Food.Chem_354_129511 Detection of organophosphorus pesticides by nanogold\/mercaptomethamidophos multi-residue electrochemical biosensor
Zhao_2021_Ann.Clin.Transl.Neurol__ Congenital myasthenic syndrome in China: genetic and myopathological characterization
Chen_2021_J.Lipid.Res__100068 Apolipoprotein A5 lowers triglyceride levels via suppression of ANGPTL3\/8-mediated LPL inhibition
Crea_2021_Eur.Heart.J_42_1119 New therapeutic targets in lipid lowering: high-sugar feeding in infants, lipoprotein(a), and lipoprotein lipase
Kawabata_2021_J.Biosci.Bioeng__ Asymmetric synthesis of intermediate for (1R,2S)-ethyl 1-amino-2-vinylcyclopropanecarboxylate by desymmetrization using engineered esterase from Bacillus subtilis
Landete_2021_Int.J.Food.Sci.Nutr__1 The use of Lactobacillus plantarum esterase genes: a biotechnological strategy to increase the bioavailability of dietary phenolic compounds in lactic acid bacteria
Lu_2021_Future.Med.Chem_13_769 Discovery, biological evaluation and molecular dynamic simulations of butyrylcholinesterase inhibitors through structure-based pharmacophore virtual screening
Reijngoud_2021_Biotechnol.Lett__ Loss of function of the carbon catabolite repressor CreA leads to low but inducer-independent expression from the feruloyl esterase B promoter in Aspergillus niger
Sabnis_2021_ACS.Med.Chem.Lett_12_312 Novel Oxazine Monoacylglycerol Lipase (MAGL) Inhibitors
Sundararajan_2021_3.Biotech_11_159 Investigation of therapeutic potential of cerium oxide nanoparticles in Alzheimer's disease using transgenic Drosophila
Thors_2021_Cutan.Ocul.Toxicol__1 Efficient agent degradation within skin is important for decontamination of percutaneously exposed VX
Wang_2021_Neurosci.Bull__ TRPV4 Regulates Soman-Induced Status Epilepticus and Secondary Brain Injury via NMDA Receptor and NLRP3 Inflammasome
Watt_2021_BMJ_372_n532 Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis
Wei_2021_Chemosphere_270_128647 Odorant degrading carboxylesterases modulate foraging and mating behaviors of Grapholita molesta
Abol-Fotouh_2021_Int.J.Biol.Macromol_181_125 Optimization, purification, and biochemical characterization of thermoalkaliphilic lipase from a novel Geobacillus stearothermophilus FMR12 for detergent formulations
Adebayo_2021_Drug.Metab.Pers.Ther__2 Long-term consumption of Moringa oleifera-supplemented diet enhanced neurocognition, suppressed oxidative stress, acetylcholinesterase activity and neuronal degeneration in rat's hippocampus
Akhtar_2021_Psychopharmacology.(Berl)__ 7,8-Dihydroxyflavone improves cognitive functions in ICV-STZ rat model of sporadic Alzheimer's disease by reversing oxidative stress, mitochondrial dysfunction, and insulin resistance
Calaf_2021_Semin.Cancer.Biol__ Role of organophosphorous pesticides and acetylcholine in breast carcinogenesis
Castro_2021_Life.Sci__119421 Modulatory effects of caffeic acid on purinergic and cholinergic systems and oxi-inflammatory parameters of streptozotocin-induced diabetic rats
Choi_2021_BMC.Anesthesiol_21_93 Comparison of neuromuscular blockade recovery co-administered with neostigmine and different doses of calcium gluconate: a randomized control trial
da Luz_2021_Sci.Total.Environ_780_146553 Can use of hydroxychloroquine and azithromycin as a treatment of COVID-19 affect aquatic wildlife? A study conducted with neotropical tadpole
Devita_2021_Aging.Clin.Exp.Res__ Acetylcholinesterase inhibitors and cognitive stimulation, combined and alone, in treating individuals with mild Alzheimer's disease
Diodato_2021_Environ.Sci.Pollut.Res.Int__ Integrated biomarker response in Mytilus chilensis exposed to untreated urban discharges along the coast of Ushuaia Bay (Beagle Channel, Argentina)
Donskov_2021_Acta.Neurol.Scand__ Overactive bladder in patients with myasthenia gravis-A cross-sectional population-based study
Dos Santos_2021_Life.Sci__119386 Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents
Hapeta_2021_Sci.Rep_11_6412 A 37-amino acid loop in the Yarrowia lipolytica hexokinase impacts its activity and affinity and modulates gene expression
Holmes_2021_Genetics__ A novel allele in the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling
Hung_2021_Chem.Biodivers__ Lantana camara L. essential oils from Vietnam: Chemical composition, molluscicidal, and mosquito larvicidal activity
Ibrahim_2021_Vet.World_14_515 Polymorphisms in hormone-sensitive lipase and leptin receptor genes and their association with growth traits in Barki lambs
Johnson_2021_Toxicol.Rep_8_571 Benzo[a]pyrene and Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced locomotor and reproductive senescence and altered biochemical parameters of oxidative damage in Canton-S Drosophila melanogaster
Kaneko_2021_Biomark.Res_9_21 Serum soluble CD26\/DPP4 titer variation is a potential prognostic biomarker in cancer therapy with a humanized anti-CD26 antibody
Kulkarni_2021_Eur.J.Pharm.Biopharm__ Design, development and in-vitro\/in-vivo evaluation of intranasally delivered Rivastigmine and N-Acetyl Cysteine loaded bifunctional niosomes for applications in combinative treatment of Alzheimer's disease
Li_2021_Bioorg.Chem_110_104826 Inducing new bioactive metabolites production from coculture of Pestalotiopsis sp. and Penicillium bialowiezense
Liu_2021_Front.Cell.Dev.Biol_9_640867 Inhibiting Monoacylglycerol Lipase Suppresses RANKL-Induced Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss
Liu_2021_Front.Neural.Circuits_15_638000 Excitatory Impact of Dental Occlusion on Dorsal Motor Nucleus of Vagus
Lu_2021_Pestic.Biochem.Physiol_173_104800 Activation of the NR2E nuclear receptor HR83 leads to metabolic detoxification-mediated chlorpyrifos resistance in Nilaparvata lugens
Lv_2021_Environ.Pollut_280_117000 Molecular response uncovers neurotoxicity of Pardosa pseudoannulata exposed to cadmium pressure
Maki-Petaja_2021_Hypertension__HYPERTENSIONAHA12016454 Mechanisms Underlying Vascular Endothelial Growth Factor Receptor Inhibition-Induced Hypertension: The HYPAZ Trial
Marins_2021_Ecotoxicology__ Environmentally relevant pesticides induce biochemical changes in Nile tilapia (Oreochromis niloticus)
Millet_2021_Anaesth.Crit.Care.Pain.Med__100847 Phenotype and genotype characteristics of 58 patients showing a prolonged effect of succinylcholine: a four-year experience
Mohamed_2021_J.Food.Biochem__e13715 Alleviation of fructose-induced Alzheimer's disease in rats by pioglitazone and decaffeinated green coffee bean extract
Morris_2021_J.Alzheimers.Dis__2 Bradycardia Due to Donepezil in Adults: Systematic Analysis of FDA Adverse Event Reporting System
Pan_2021_Cureus_13_e13495 CD26\/Dipeptidyl Peptidase IV and Its Multiple Biological Functions
Posadas-Sanchez_2021_Life.Sci_276_119410 Dipeptidylpeptidase-4 levels and DPP4 gene polymorphisms in patients with COVID-19. Association with disease and with severity
Rege_2021_Drugs.Aging__ Antipsychotic Initiation Among Older Dementia Patients Using Cholinesterase Inhibitors: A National Retrospective Cohort Study
Rhee_2021_Diabetes.Metab.J__ Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19
Saleem_2021_Metab.Brain.Dis_36_1231 Antiparkinsonian activity of Cucurbita pepo seeds along with possible underlying mechanism
Sangaleti_2021_Front.Immunol_12_613979 The Cholinergic Drug Galantamine Alleviates Oxidative Stress Alongside Anti-inflammatory and Cardio-Metabolic Effects in Subjects With the Metabolic Syndrome in a Randomized Trial
Santos_2021_Chemosphere_277_130262 Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages
Schaltenberg_2021_Front.Cardiovasc.Med_8_628235 Endothelial Lipase Is Involved in Cold-Induced High-Density Lipoprotein Turnover and Reverse Cholesterol Transport in Mice
Sole_2021_Chemosphere_277_130283 Biomarker responses and metabolism in Lumbricus terrestris exposed to drugs of environmental concern, an in vivo and in vitro approach
Tiwari_2021_Sci.Rep_11_7042 Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers
Wang_2021_J.Sep.Sci__ Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays
Waseem_2021_ACS.Omega_6_7910 Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer's Disease
Wigenstam_2021_Toxicol.Appl.Pharmacol__115512 Efficacy of atropine and scopolamine on airway contractions following exposure to the nerve agent VX
Yang_2021_Bioorg.Med.Chem_37_116109 Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia
Zhang_2021_Talanta_228_122268 Smart nanozyme of silver hexacyanoferrate with versatile bio-regulated activities for probing different targets
Aissa_2021_Bioorg.Med.Chem.Lett__128000 Fiaud's Acid, a novel organocatalyst for diastereoselective bis alpha-aminophosphonates synthesis with in-vitro biological evaluation of antifungal, antioxidant and enzymes inhibition potential
Amin_2021_Bioorg.Chem_110_104792 Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's disease
Amin_2021_Front.Physiol_12_628107 Melatonin-Pretreated Mesenchymal Stem Cells Improved Cognition in a Diabetic Murine Model
Atrahimovich_2021_Metabolites_11_ Galantamine Quantity and Alkaloid Profile in the Bulbs of Narcissus tazetta and daffodil cultivars (Amaryllidaceae) Grown in Israel
Badshah_2021_Molecules_26_ Isolation, Characterization, and Medicinal Potential of Polysaccharides of Morchella esculenta
Cairone_2021_Molecules_26_ Health Potential of Clery Strawberries: Enzymatic Inhibition and Anti-Candida Activity Evaluation
Capolupo_2021_Nanomaterials.(Basel)_11_ A Comparative Assessment of the Chronic Effects of Micro- and Nano-Plastics on the Physiology of the Mediterranean Mussel Mytilus galloprovincialis
Cash_2021_Neurobiol.Aging_103_31 Clinicopathological correlations and cholinesterase expression in early-onset familial Alzheimer's disease with the presenilin 1 mutation, Leu235Pro
Choi_2021_Mar.Environ.Res_168_105320 Impact of polyethylene terephthalate microfiber length on cellular responses in the Mediterranean mussel Mytilus galloprovincialis
Contreras-Aguilar_2021_Animals.(Basel)_11_ Changes in Saliva Analytes in Dairy Cows during Peripartum: A Pilot Study
Dall'Acqua_2021_Molecules_26_ Evaluation of Antioxidant and Enzyme Inhibition Properties of Croton hirtus L'Hr. Extracts Obtained with Different Solvents
de Souza_2021_Colloids.Surf.B.Biointerfaces_203_111721 The liquid crystalline phase behaviour of a nasal formulation modifies the brain disposition of donepezil in rats in the treatment of Alzheimer's disease
Deng_2021_Toxins.(Basel)_13_ Lipolytic Activity of a Carboxylesterase from Bumblebee (Bombus ignitus) Venom
Dymek_2021_Molecules_26_1626 Optimization of Pressurized Liquid Extraction of Lycopodiaceae Alkaloids Obtained from Two Lycopodium Species
Emam_2021_Molecules_26_ Phytochemical Profiling of Lavandula coronopifolia Poir. Aerial Parts Extract and Its Larvicidal, Antibacterial, and Antibiofilm Activity Against Pseudomonas aeruginosa
Felix_2021_Pharmaceuticals.(Basel)_14_ Chemical Composition, Larvicidal Activity, and Enzyme Inhibition of the Essential Oil of Lippia grata Schauer from the Caatinga Biome against Dengue Vectors
Gao_2021_Int.J.Mol.Sci_22_ Design and Synthesis of Ranitidine Analogs as Multi-Target Directed Ligands for the Treatment of Alzheimer's Disease
Gonzalez-Morales_2021_J.Med.Entomol__ Resistance to Fipronil in the Common Bed Bug (Hemiptera: Cimicidae)
Guenther_2021_Eur.J.Anaesthesiol_38_554 Low cholinesterase activity is a risk factor for delirium after cardiac surgery: A prospective cohort study
Jarzebowski_2021_Elife_10_ Impaired spatial learning and suppression of sharp wave ripples by cholinergic activation at the goal location
Jekayinoluwa_2021_Plants.(Basel)_10_ Transgenic Expression of dsRNA Targeting the Pentalonia nigronervosa acetylcholinesterase Gene in Banana and Plantain Reduces Aphid Populations
Khalid_2021_Mar.Pollut.Bull_167_112295 Are bio-based and biodegradable microplastics impacting for blue mussel (Mytilus edulis)?
Kim_2021_Biomolecules_11_ Nematicidal Activity of Benzyloxyalkanols against Pine Wood Nematode
Kim_2021_Fish.Shellfish.Immunol__ Effects on the survival rates, hematological parameters, and neurotransmitters in olive flounders, Paralichthys olivaceus, reared in bio-floc and seawater by Streptococcus iniae challenge
Kim_2021_Evid.Based.Complement.Alternat.Med_2021_8884243 Standardized Extract (HemoHIM) Protects against Scopolamine-Induced Amnesia in a Murine Model
Kos_2021_Int.J.Mol.Sci_22_ Synthesis and Hybrid SAR Property Modeling of Novel Cholinesterase Inhibitors
Kunnaja_2021_Molecules_26_ In Vitro Antioxidant Activity of Litsea martabanica Root Extract and Its Hepatoprotective Effect on Chlorpyrifos-Induced Toxicity in Rats
Lagrutta_2021_Heliyon_7_e06539 Nuclear-lipid-droplet proteome: carboxylesterase as a nuclear lipase involved in lipid-droplet homeostasis
Li_2021_Front.Cell.Dev.Biol_9_640667 Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes
Lorke_2021_Int.J.Mol.Sci_22_ Experimental and Established Oximes as Pretreatment before Acute Exposure to Azinphos-Methyl
Matosevic_2021_Pharmaceutics_13_ Quinuclidine-Based Carbamates as Potential CNS Active Compounds
Min_2021_Life.(Basel)_11_ A Novel Dipeptidyl Peptidase-4 Inhibitor DA-1229 Ameliorates Tubulointerstitial Fibrosis in Cyclosporine Nephrotoxicity in Mice
Moriou_2021_Mar.Drugs_19_ Bioactive Bromotyrosine Derivatives from the Pacific Marine Sponge Suberea clavata (Pulitzer-Finali, 1982)
Motter_2021_Alzheimers.Dement.(Amst)_13_e12158 Odor identification impairment and cholinesterase inhibitor treatment in Alzheimer's disease
Oshodi_2021_Mol.Biol.Rep__ Molecular mechanisms involved in the prevention and reversal of ketamine-induced schizophrenia-like behavior by rutin: the role of glutamic acid decarboxylase isoform-67, cholinergic, Nox-2-oxidative stress pathways in mice
Paradhipta_2021_Microorganisms_9_ Effects of Inoculants Producing Antifungal and Carboxylesterase Activities on Corn Silage and Its Shelf Life against Mold Contamination at Feed-Out Phase
Petkov_2021_Z.Naturforsch.C.J.Biosci__ Receptor-mediated biological effects of extracts obtained from three Asplenium species
Qiu_2021_Front.Cardiovasc.Med_8_639541 Donepezil Ameliorates Pulmonary Arterial Hypertension by Inhibiting M2-Macrophage Activation
Queda_2021_Molecules_26_ Novel Donepezil-Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer's Disease
Quimque_2021_ACS.Omega_6_8403 Potential Cancer- and Alzheimer's Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
Ramalakshmi_2021_Mini.Rev.Med.Chem__ Multitarget Directed Ligand Approaches for Alzheimer's Disease: A Complete Review
Ramirez_2021_Br.J.Clin.Pharmacol__ Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib
Salau_2021_Reprod.Toxicol__ Vanillin Exerts Therapeutic Effects against Hyperglycemia-Altered Glucose Metabolism and Purinergic Activities in Testicular Tissues of Diabetic Rats
Shabbir_2021_Toxins.(Basel)_13_ Assessing the Single and Combined Toxicity of Chlorantraniliprole and Bacillus thuringiensis (GO33A) against Four Selected Strains of Plutella xylostella (Lepidoptera: Plutellidae), and a Gene Expression Analysis
Sheyn_2021_Int.Urogynecol.J__ Evaluation of the relationship of cholinergic metabolites in urine and urgency urinary incontinence
Silva_2021_Biology.(Basel)_10_ Asparagopsis armata Exudate Cocktail: The Quest for the Mechanisms of Toxic Action of an Invasive Seaweed on Marine Invertebrates
Simeonova_2021_Molecules_26_ A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders
Sohn_2021_Mol.Neurobiol__ Ficus erecta Thunb Leaves Alleviate Memory Loss Induced by Scopolamine in Mice via Regulation of Oxidative Stress and Cholinergic System
Takahashi_2021_Behav.Brain.Res__113283 Activation of cholinergic system partially rescues olfactory dysfunction-induced learning and memory deficit in mice
Tampio_2021_Int.J.Pharm__120565 Improved L-Type Amino Acid Transporter 1 (LAT1)-Mediated Delivery of Anti-Inflammatory Drugs into Astrocytes and Microglia with Reduced Prostaglandin Production
Trotti_2021_Dement.Geriatr.Cogn.Dis.Extra_11_19 Cerebrospinal Fluid Hypocretin and Nightmares in Dementia Syndromes
Vasilopoulou_2021_Br.J.Pharmacol__ Disease-modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: A Comparative study with donepezil
Vieira_2021_Curr.Opin.Neurobiol_69_93 The role of NMDA receptor and neuroligin rare variants in synaptic dysfunction underlying neurodevelopmental disorders
Wu_2021_Insects_12_ Exposure of Helicoverpa armigera Larvae to Plant Volatile Organic Compounds Induces Cytochrome P450 Monooxygenases and Enhances Larval Tolerance to the Insecticide Methomyl
Xia_2021_Proc.Natl.Acad.Sci.U.S.A_118_ Imaging in vivo acetylcholine release in the peripheral nervous system with a fluorescent nanosensor
Xue_2021_J.Biomol.Struct.Dyn__1 Using structural analysis to clarify the impact of single nucleotide variants in neurexin\/neuroligin revealed in clinical genomic sequencing
Zhang_2021_Chembiochem__ A bi-enzymatic cascade pathway towards optically pure FAHFAs
Ackerman_2021_Nature__ Astrocytes close a motor circuit critical period
Ali_2021_Int.J.Biol.Macromol__ Sequence and structure-based method to predict diacylglycerol lipases in protein sequence
Baloch_2021_Curr.Microbiol__ The Occurrence of Triple Catalytic Characteristics of Yeast Lipases and Their Application Prospects in Biodiesel Production from Non-Edible Jatropha curcas Oil in a Solvent-Free System
Banna_2021_Biol.Trace.Elem.Res__ Parental Lead Exposure Promotes Neurobehavioral Disorders and Hepatic Dysfunction in Mouse Offspring
Barroso_2021_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_39_100826 Transcriptomic and proteomic analysis of the underlying mechanisms of digestion of triacylglycerols and phosphatides and absorption and fate of fatty acids along the midgut of Musca domestica
Capolupo_2021_Environ.Pollut_283_117081 The sub-lethal impact of plastic and tire rubber leachates on the Mediterranean mussel Mytilus galloprovincialis
Chauhan_2021_J.Lipids_2021_5583114 Effects of Starvation on the Levels of Triglycerides, Diacylglycerol, and Activity of Lipase in Male and Female Drosophila Melanogaster
Dall'Acqua_2021_Front.Pharmacol_12_660735 Hypericum triquetrifolium and H. neurocalycinum as Sources of Antioxidants and Multi-Target Bioactive Compounds: A Comprehensive Characterization Combining In Vitro Bioassays and Integrated NMR and LC-MS Characterization by Using a Multivariate Approach
Dhanasobhon_2021_Neurobiol.Dis__105363 Enhanced analgesic cholinergic tone in the spinal cord in a mouse model of neuropathic pain
El-Sayad_2021_Acta.Parasitol__ microRNA-155 Expression and Butyrylcholinesterase Activity in the Liver Tissue of Mice Infected with Toxoplasma gondii (Avirulent and Virulent Strains)
Gherbovet_2021_Beilstein.J.Org.Chem_17_325 Regioselective chemoenzymatic syntheses of ferulate conjugates as chromogenic substrates for feruloyl esterases
Goncalves_2021_Eur.J.Pharmacol__174089 Endogenous opioid and cannabinoid systems modulate the muscle pain: a pharmacological study into the peripheral site
Gordon_2021_Exp.Neurol__113717 Peripheral nerves preferentially regenerate in intramuscular endoneurial tubes to reinnervate denervated skeletal muscles
Halminen_2021_J.Alzheimers.Dis__ Early Start of Anti-Dementia Medication Delays Transition to 24-Hour Care in Alzheimer's Disease Patients: A Finnish Nationwide Cohort Study
Hamulakova_2021_Future.Med.Chem__ Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease
Han_2021_Biotechnol.Lett__ Surface charge engineering of Thermomyces lanuginosus lipase improves enzymatic activity and biodiesel synthesis
Huang_2021_Adv.Exp.Med.Biol_1303_107 Roles of Genetic Predisposition in the Sex Bias of Pulmonary Pathophysiology, as a Function of Estrogens : Sex Matters in the Prevalence of Lung Diseases
Jaiswal_2021_ChemMedChem__ Anticancer potential of small molecule inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase - A mini-review
Kabuye_2021_Indian.J.Tuberc_68_179 Lysosomal acid lipase gene single nucleotide polymorphism and pulmonary tuberculosis susceptibility
Li_2021_J.Food.Sci__ Enzymatic acylation of rutin with benzoic acid ester and lipophilic, antiradical, and antiproliferative properties of the acylated derivatives
Li_2021_Environ.Health.Perspect_129_47008 Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition
Luz_2021_An.Acad.Bras.Cienc_93_e20190672 Lipase production by microorganisms isolated from the Serra de Ouro Branco State Park
Ma_2021_Ann.Palliat.Med__ Comparison of four markers of hepatic fibrosis and hepatic function indices in patients with liver cirrhosis and hepatoma
Madacki_2021_Int.J.Mol.Sci_22_ Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives
Makhaeva_2021_Eur.J.Med.Chem_218_113385 Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold
Martinez_2021_Environ.Sci.Pollut.Res.Int__ Comparison of biomarker responses after acute and chronic bioassays in Lumbriculus variegatus
Muller_2021_Alzheimers.Dement.(N.Y)_7_e12153 Structural MRI of the basal forebrain as predictor of cognitive response to galantamine in healthy older adults-A randomized controlled double-blinded crossover study
Munch_2021_Eur.J.Pediatr__ Digestive enzyme replacement relieves growth failure in preterm infants with poor exocrine pancreatic function: a retrospective case series
Nakagawa_2021_Surg.Today__ Proximal subtotal pancreatectomy as an alternative to total pancreatectomy for malnourished patients
Nardello_2021_BMC.Med.Genomics_14_98 A paradigmatic autistic phenotype associated with loss of PCDH11Y and NLGN4Y genes
Nascimento_2021_Environ.Pollut_283_117054 Polyethylene glycol acute and sub-lethal toxicity in neotropical Physalaemus cuvieri tadpoles (Anura, Leptodactylidae)
Nurfazilah_2021_Steroids__108832 Biocatalytic modifications of ethynodiol diacetate by fungi, anti-proliferative activity, and acetylcholineterase inhibitory of its transformed products
Oguro_2021_Int.J.Mol.Sci_22_ DHA and Its Metabolites Have a Protective Role against Methylmercury-Induced Neurotoxicity in Mouse Primary Neuron and SH-SY5Y Cells
Pasandideh_2021_Int.J.Biol.Macromol__ Evaluation of antioxidant and inhibitory properties of Citrus aurantium L. on the acetylcholinesterase activity and the production of amyloid nano-bio fibrils
Peng_2021_J.Food.Biochem__e13667 Stability comparison of four lipases and catalytic mechanism during the synthesis of 1,3-di-oleic-2-medium chain triacylglycerols in a trace water-in-oil system: Experimental analyses and computational simulations
Perczyk_2021_Biochim.Biophys.Acta.Biomembr_1863_183620 Simultaneous action of microbial phospholipase C and lipase on model bacterial membranes - Modeling the processes crucial for bioaugmentation
Rakhmat,_2021_Diabetes.Metab.Syndr_15_777 Dipeptidyl peptidase-4 (DPP-4) inhibitor and mortality in coronavirus disease 2019 (COVID-19) - A systematic review, meta-analysis, and meta-regression
Sahaka_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1173_122674 Quantitative monitoring of galactolipid hydrolysis by pancreatic lipase-related protein 2 using thin layer chromatography and thymol-sulfuric acid derivatization
Santillan_2021_Environ.Sci.Pollut.Res.Int__ Exposure to environmental concentrations of fipronil induces biochemical changes on a neotropical freshwater fish
Spitler_2021_Sci.Rep_11_7873 Regulation of plasma triglyceride partitioning by adipose-derived ANGPTL4 in mice
Stojiljkovic_2021_Chem.Biol.Interact__109463 Effects of memantine and its metabolite Mrz 2\/373 on soman-induced inhibition of acetylcholinesterase in vitro
Taha_2021_J.Complement.Integr.Med__ Association of microsomal epoxide hydrolase gene (fast genotype) with lung functions impairment in wood workers
Valente_2021_Eur.J.Pharm.Sci__105831 Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma and liver hydrolysis
Wang_2021_Front.Psychiatry_12_638328 Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats
Yan_2021_Mikrochim.Acta_188_162 Colorimetric detection of acetylcholinesterase and its inhibitor based on thiol-regulated oxidase-like activity of 2D palladium square nanoplates on reduced graphene oxide
Adefegha_2021_Toxicol.Res_37_249 beta-caryophyllene improves sexual performance via modulation of crucial enzymes relevant to erectile dysfunction in rats
Ahammed_2021_Adv.Pharmacol.Pharm.Sci_2021_5569054 Acetylcholinesterase Inhibitory and Antioxidant Activity of the Compounds Isolated from Vanda roxburghii
Ahmed_2021_J.Biomol.Struct.Dyn__1 Computational and SAXS-based structure insights of pectin acetyl esterase (CtPae12B) of family 12 carbohydrate esterase from Clostridium thermocellum ATCC 27405
Ajima_2021_Environ.Sci.Pollut.Res.Int__ Sublethal diclofenac induced oxidative stress, neurotoxicity, molecular responses and alters energy metabolism proteins in Nile tilapia, Oreochromis niloticus
Akpa_2021_Toxicol.Res_37_163 Protective effect of fisetin against subchronic chlorpyrifos-induced toxicity on oxidative stress biomarkers and neurobehavioral parameters in adult male albino mice
Araujo_2021_ACS.Med.Chem.Lett_12_548 Glucosamine and Its Analogues as Modulators of Amyloid-beta Toxicity
Babaee_2021_Chem.Biodivers__ Design, synthesis, and molecular docking of some novel tacrine based cyclopentapyranopyridin- and tetrahydropyranoquinolin-kojic acid derivatives as anti-acetylcholinesterase agents
Basalan_2021_Arch.Environ.Contam.Toxicol__ Effects of Different Ammonia Levels on Tribenuron Methyl Toxicity in Daphnia magna
Behera_2021_Phys.Chem.Chem.Phys_23_7302 An atomistic view of solvent-free protein liquids: the case of Lipase A
Bentham_2021_Curr.Alzheimer.Res__ Cerebrovascular Pathology and Responsiveness to Treatment in Alzheimer's Disease: A Systematic Review
Corrado_2021_Chembiochem__ High regio- and stereoselective multi-enzymatic synthesis of all phenylpropanolamine stereoisomers from beta-methylstyrene
Dada_2021_J.Complement.Integr.Med__ Evaluation of different almond (Terminalia catappa) extracts against oxidative stress induced by cyclosporine in brain and liver of rats
El-Koofy_2021_Lipids.Health.Dis_20_38 Management strategy and novel ophthalmological findings in neonatal severe hypertriglyceridemia: a case report and literature review
Fang_2021_J.Med.Entomol__ Molecular Analysis of Targeted Insecticide Resistance Gene Mutations in Field-Caught Mosquitos of Medical Importance From Saudi Arabia
Godoy_2021_Front.Physiol_12_643281 An Overview of Antennal Esterases in Lepidoptera
Hetrick_2021_ACS.Chem.Biol__ Endogenous Enzymes Enable Antimicrobial Activity
Khushboo_2021_Mini.Rev.Med.Chem__ Biomedical Implications of Plant-Based Principles as Antidepressants: Prospects for Novel Drug Development
Kuvelkar_2021_Indian.J.Pathol.Microbiol_64_266 Estimation of plasma and RBC acetylcholinesterase in children: An evaluation tool for Hirschsprung's disease?
Leng_2021_Nat.Rev.Neurol_17_157 Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Lin_2021_Exp.Ther.Med_21_548 Curcumin relieves mice gastric emptying dysfunction induced by L-arginine and atropine through interstitial cells of Cajal
Malafaia_2021_Sci.Total.Environ_783_146994 Green toxicology approach involving polylactic acid biomicroplastics and neotropical tadpoles: (Eco)toxicological safety or environmental hazard?
Marques_2021_Curr.Opin.Struct.Biol_69_19 Web-based tools for computational enzyme design
Muniz_2021_Environ.Pollut_283_117096 Moxidectin toxicity to zebrafish embryos: Bioaccumulation and biomarker responses
Nicholson_2021_Curr.Res.Food.Sci_4_163 Lipase-catalyzed glycerolysis extended to the conversion of a variety of edible oils into structural fats
Ozdemir_2021_Protein.J__ Identification and Heterologous Production of a Lipase from Geobacillus kaustophilus DSM 7263(T) and Tailoring Its N-Terminal by a His-Tag Epitope
Polichnowski_2021_Am.J.Physiol.Regul.Integr.Comp.Physiol__ Autonomic and cholinergic mechanisms mediating cardiovascular and temperature effects of donepezil in conscious mice
Sagbohan_2021_Parasit.Vectors_14_202 Intensity and mechanisms of deltamethrin and permethrin resistance in Anopheles gambiae s.l. populations in southern Benin
Shahrivar-Gargari_2021_Arch.Pharm.(Weinheim)__e2000453 Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies
Silakari_2021_ACS.Chem.Neurosci__ Systematic In Silico Design, Synthesis, and Biological Studies of Some Novel 1,4-Benzoquinone Derivatives for the Prospective Management of Cognitive Decline
Suharti_2021_Heliyon_7_e06542 Cloning, heterologous expression, and characterization of a novel thioesterase from natural sample
Takahashi_2021_Drug.Metab.Pharmacokinet_38_100391 Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase
Takano_2021_Surg.Today__ Preoperative serum cholinesterase levels as a risk factor of postoperative complications for the elderly undergoing emergency surgery
Ucar_2021_Drug.Chem.Toxicol__1 Neurotoxic responses of rainbow trout (Oncorhynchus mykiss) exposed to fipronil: multi-biomarker approach to illuminate the mechanism in brain
Wan_2021_ACS.Omega_6_9960 Late-Stage Modification of Medicine: Pd-Catalyzed Direct Synthesis and Biological Evaluation of N-Aryltacrine Derivatives
Wang_2021_J.Environ.Sci.Health.B__1 Plasma cholinesterase activity is influenced by interactive effect between omethoate exposure and CYP2E1 polymorphisms
Zandi_2021_Arch.Iran.Med_24_233 Prospects of Saffron and its Derivatives in Alzheimer's Disease
Zarei_2021_Heliyon_7_e06683 Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4H)-yl)methyl) pyridin-1-ium derivatives (BOPs) as potential dual inhibitors of acetylcholinesterase and butyrylcholinesterase
Zeng_2021_J.Biotechnol__ Immobilized lipase catalytic synthesis of phenolamides and their potential against alpha-glucosidase
Zhang_2021_Nat.Prod.Bioprospect__ Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz
Ahmed_2021_J.Venom.Anim.Toxins.Incl.Trop.Dis_27_e20200047 Kinetic and toxicological effects of synthesized palladium(II) complex on snake venom (Bungarus sindanus) acetylcholinesterase
Angrand_2021_Toxicology__152787 Persistent brainwave disruption and cognitive impairment induced by acute sarin surrogate sub-lethal dose exposure
Borioni_2021_Bioorg.Chem_111_104893 Design, synthesis and evaluation of cholinesterase hybrid inhibitors using a natural steroidal alkaloid as precursor
Cattel_2021_Evol.Appl_14_1009 A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: From genomic characterization to high-throughput field detection
Cavalcante_2021_Acta.Physiol.(Oxf)__e13663 Benefits of pharmacological and electrical cholinergic stimulation in hypertension and heart failure
Gorecki_2021_Eur.J.Med.Chem_219_113434 Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors
Graikou_2021_Planta.Med__ Chemical Characterisation-Biological Evaluation of Greek Cultivar Cardoon Seeds (Cynara cardunculus). A By-product with Potential High Added Value
Guo_2021_Anal.Chem__ Multienzyme-Targeted Fluorescent Probe as a Biosensing Platform for Broad Detection of Pesticide Residues
Gurunathan_2021_Int.J.Nanomedicine_16_2849 Palladium Nanoparticle-Induced Oxidative Stress, Endoplasmic Reticulum Stress, Apoptosis, and Immunomodulation Enhance the Biogenesis and Release of Exosome in Human Leukemia Monocytic Cells (THP-1)
Hawkey_2021_Neurotoxicol.Teratol__106985 Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact?
Hofmann_2021_Chemistry_27_6015 Azobioisosteres of Curcumin with Pronounced Activity against Amyloid Aggregation, Intracellular Oxidative Stress, and Neuroinflammation
Kamoun_2021_Heliyon_7_e06717 In vitro lipolysis and physicochemical characterization of unconventional star anise oil towards the development of new lipid-based drug delivery systems
Karmakar_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109058 Nonylphenol exposure in Labeo rohita (Ham.): Evaluation of behavioural response, histological, haematological and enzymatic alterations
Khadrawy_2021_Neurotoxicol_85_1 Protective effect of nanocurcumin against neurotoxicity induced by doxorubicin in rat's brain
Manfo_2021_Toxicol.Res.(Camb)_10_232 Occupational use of agrochemicals results in inhibited cholinesterase activity and altered reproductive hormone levels in male farmers from Buea, Cameroon
Mohammadi-Farani_2021_Behav.Pharmacol__ Sodium butyrate enhances fear extinction and rescues hippocampal acetylcholinesterase activity in a rat model of posttraumatic stress disorder
Osawa_2021_Exp.Gerontol__111374 Physical activity and all-cause mortality and mediators of the association in the very old
Sandhu_2021_Mol.Divers__ Machine learning-based modeling to predict inhibitors of acetylcholinesterase
Sarangi_2021_Neurol.India_69_252 Chronic Neurological Disorders: Genetic and Epigenetic Markers for Monitoring of Pharmacotherapy
Senizza_2021_Food.Funct_12_3443 Metabolomic profiling and biological properties of six Limonium species: novel perspectives for nutraceutical purposes
Sohn_2021_Integr.Med.Res_10_100723 Korean traditional herbal formula Soshiho-tang attenuates memory impairment and neuronal damage in mice with amyloid-beta-induced Alzheimer's disease
Szafran_2021_Chem.Res.Toxicol__ Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice
Tong_2021_Pharmacol.Ther__107859 Soluble ligands as drug targets for treatment of inflammatory bowel disease
Varshney_2021_CNS.Neurol.Disord.Drug.Targets__ Role of natural plant products against Alzheimer's disease
Wang_2021_Chem.Biol.Interact__109489 Discovery of 7-O-1, 2, 3-triazole hesperetin derivatives as multi-target-directed ligands against Alzheimer's disease
Wang_2021_Environ.Pollut_284_117182 Responses of Asian clams (Corbicula fluminea) to low concentration cadmium stress: Whether the depuration phase restores physiological characteristics
Ye_2021_Bioorg.Chem_111_104895 Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents
Yves_2021_Brain.Res__147493 NLX-101, a cortical 5-HT(1A) receptor biased agonist, reverses scopolamine-induced deficit in the delayed non-matching to position model of cognition
Adetunji_2021_Braz.J.Microbiol__ Production strategies and biotechnological relevance of microbial lipases: a review
Afzal_2021_Molecules_26_ Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase
Ahmed_2021_Biomed.Pharmacother_139_111609 Potential therapeutic natural products against Alzheimer's disease with Reference of Acetylcholinesterase
Alhatali_2021_Clin.Toxicol.(Phila)__1 A cluster of tetrodotoxin poisoning in Oman
Birsan_2021_Foods_10_ Anticholinesterase Activities of Different Solvent Extracts of Brewer's Spent Grain
Codony_2021_J.Med.Chem__ From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
De Boer_2021_Biomolecules_11_ A Comprehensive Review of Cholinesterase Modeling and Simulation
Dhuria_2021_Drug.Metab.Rev__1 Recent developments in predicting CYP-Independent metabolism
Dias_2021_Environ.Monit.Assess_193_317 DNA damage and biochemical responses in estuarine bivalve Donax incarnatus (Gmelin, 1791) exposed to sub-lethal concentrations of an organophosphate pesticide monocrotophos
Dixon_2021_Genes.(Basel)_12_ The Role of Lipid Sensing Nuclear Receptors (PPARs and LXR) and Metabolic Lipases in Obesity, Diabetes and NAFLD
Dongus_2021_Curr.Opin.Plant.Biol_62_102039 EDS1 signalling: At the nexus of intracellular and surface receptor immunity
Dora_2021_Int.J.Mol.Sci_22_ Quercetin Attenuates Brain Oxidative Alterations Induced by Iron Oxide Nanoparticles in Rats
Emerson_2021_G3.(Bethesda)__ Acetylcholine Signaling Genes are Required for Cocaine-Stimulated Egg Laying in Caenorhabditis elegans
Faraone_2021_Phytochemistry_187_112781 Screening of in vitro and in silico alpha-amylase, alpha-glucosidase, and lipase inhibitory activity of oxyprenylated natural compounds and semisynthetic derivatives
Feng_2021_Foods_10_ Fabrication of Nano\/Micro-Structured Electrospun Detection Card for the Detection of Pesticide Residues
Ferreira_2021_Xenobiotica__1 Polymorphisms in xenobiotic metabolism-related genes in patients with hepatocellular carcinoma: a case-control study
Fitzgerald_2021_Behav.Brain.Res__113323 Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test
Gowayed_2021_BMC.Pharmacol.Toxicol_22_24 The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation
Grajales-Hernandez_2021_Appl.Microbiol.Biotechnol__ Approaches for the enzymatic synthesis of alkyl hydroxycinnamates and applications thereof
Griffin_2021_Cells_10_ Integrated Action of Autophagy and Adipose Tissue Triglyceride Lipase Ameliorates Diet-Induced Hepatic Steatosis in Liver-Specific PLIN2 Knockout Mice
Guo_2021_Microorganisms_9_ Characterization of Two Unique Cold-Active Lipases Derived from a Novel Deep-Sea Cold Seep Bacterium
Halder_2021_Front.Immunol_12_660342 Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Hashem_2021_Mol.Neurobiol__ Inhibition of 2-Arachidonoylglycerol Metabolism Alleviates Neuropathology and Improves Cognitive Function in a Tau Mouse Model of Alzheimer's Disease
Hinkaew_2021_Molecules_26_ A Comparison of the Nutritional and Biochemical Quality of Date Palm Fruits Obtained Using Different Planting Techniques
Hosokawa_2021_Nat.Neurosci__ CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation
Hudacova_2021_Int.J.Mol.Sci_22_ Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells
Jeon_2021_ACS.Appl.Mater.Interfaces__ Neuroligin-1-Modified Electrodes for Specific Coupling with a Presynaptic Neuronal Membrane
Jonnalagadda_2021_Int.J.Mol.Sci_22_ A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis
Khafaga_2021_Sci.Total.Environ_785_147384 Boswellia serrata suppress fipronil-induced neuronal necrosis and neurobehavioral alterations via promoted inhibition of oxidative\/inflammatory\/apoptotic pathways
Kim_2021_Prostate.Int_9_31 Enhanced inhibition of tumor growth using TRAIL-overexpressing adipose-derived stem cells in combination with the chemotherapeutic agent CPT-11 in castration-resistant prostate cancer
Kim_2021_Plants.(Basel)_10_ Simultaneous Quantification of Four Marker Compounds in Bauhinia coccinea Extract and Their Potential Inhibitory Effects on Alzheimer's Disease Biomarkers
Kiziltas_2021_Molecules_26_ LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kinkor (Ferulago stellata)
Lecoutey_2021_Molecules_26_ Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer's Disease Treatment through Rigidification Strategy
Li_2021_Exp.Appl.Acarol__ Acetylcholinesterase target sites for developing environmentally friendly insecticides against Tetranychus urticae (Acari: Tetranychidae)
Luo_2021_J.Biol.Chem__100667 Inhibition of soluble epoxide hydrolase alleviates insulin resistance and hypertension via downregulation of SGLT2 in the mouse kidney
Malafaia_2021_Int.J.Mol.Sci_22_ Chromeno[3,4-b]xanthones as First-in-Class AChE and Abeta Aggregation Dual-Inhibitors
Mansinhos_2021_Antioxidants.(Basel)_10_ Ultrasonic-Assisted Extraction and Natural Deep Eutectic Solvents Combination: A Green Strategy to Improve the Recovery of Phenolic Compounds from Lavandula pedunculata subsp. lusitanica (Chaytor) Franco
Martins_2021_Prep.Biochem.Biotechnol__1 Solid-state fermentation production and characterization of an alkaline lipase from a newly isolated Burkholderia gladioli strain
McReynolds_2021_Front.Physiol_12_663869 Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections
Moyano_2021_Food.Chem.Toxicol_152_112241 Chlorpyrifos induces cell proliferation in MCF-7 and MDA-MB-231 cells, through cholinergic and Wnt\/beta-catenin signaling disruption, AChE-R upregulation and oxidative stress generation after single and repeated treatment
Mphahlele_2021_Antioxidants.(Basel)_10_ In Vitro Enzymatic and Kinetic Studies, and In Silico Drug-Receptor Interactions, and Drug-Like Profiling of the 5-Styrylbenzamide Derivatives as Potential Cholinesterase and beta-Secretase Inhibitors with Antioxidant Properties
Neskovic_2021_Front.Pharmacol_12_656748 Different Pharmacokinetics of Tramadol, O-Demethyltramadol and N-Demethyltramadol in Postoperative Surgical Patients From Those Observed in Medical Patients
Nguyen_2021_Nat.Prod.Res__1 A new flavonoid from the leaves of Garcinia mckeaniana Craib and alpha-glucosidase and acetylcholinesterase inhibitory activities
Ojo_2021_Molecules_26_ Deciphering the Interactions of Bioactive Compounds in Selected Traditional Medicinal Plants against Alzheimer's Diseases via Pharmacophore Modeling, Auto-QSAR, and Molecular Docking Approaches
Park_2021_Plants.(Basel)_10_ Establishment of a Rapid Micropropagation System for Kaempferia parviflora Wall. Ex Baker: Phytochemical Analysis of Leaf Extracts and Evaluation of Biological Activities
Petrilla_2021_Toxins.(Basel)_13_ A Comprehensive Study Monitoring the Venom Composition and the Effects of the Venom of the Rare Ethiopian Endemic Snake Species Bitis parviocula
Pham_2021_Micromachines.(Basel)_12_ A Fluidics-Based Biosensor to Detect and Characterize Inhibition Patterns of Organophosphate to Acetylcholinesterase in Food Materials
Pineau_2021_Plant.Sci_307_110905 CYP77B1 a fatty acid epoxygenase specific to flowering plants
Piner_2021_Toxics_9_ In Vivo Effects of Neonicotinoid-Sulfoximine Insecticide Sulfoxaflor on Acetylcholinesterase Activity in the Tissues of Zebrafish (Danio rerio)
Rani_2021_Biomolecules_11_ Short- and Long-Term Social Recognition Memory Are Differentially Modulated by Neuronal Histamine
Robert_2021_Cells_10_ The Endothelium Is Both a Target and a Barrier of HDL's Protective Functions
Santos_2021_Aquat.Toxicol_235_105814 Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure
Senol Deniz_2021_Molecules_26_ Outlining In Vitro and In Silico Cholinesterase Inhibitory Activity of Twenty-Four Natural Products of Various Chemical Classes: Smilagenin, Kokusaginine, and Methyl Rosmarinate as Emboldening Inhibitors
Stanley_2021_Alzheimers.Dement__ The Clinician's Interview-Based Impression of Change (Plus caregiver input) and goal attainment in two dementia drug trials: Clinical meaningfulness and the initial treatment response
Stasilowicz_2021_Int.J.Mol.Sci_22_ Combinations of Piperine with Hydroxypropyl-beta-Cyclodextrin as a Multifunctional System
Stavrakov_2021_Molecules_26_ Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening
Studzinska-Sroka_2021_Cancers.(Basel)_13_ Permeability of Hypogymnia physodes Extract Component-Physodic Acid through the Blood-Brain Barrier as an Important Argument for Its Anticancer and Neuroprotective Activity within the Central Nervous System
Sun_2021_Behav.Sci.(Basel)_11_ Treatment of Parkinson's Disease with Cognitive Impairment: Current Approaches and Future Directions
To_2021_J.Clin.Med_10_ Cognitive Dysfunction in a Mouse Model of Cerebral Ischemia Influences Salivary Metabolomics
Tsai_2021_Am.J.Hum.Genet__ Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration
Ul_2021_Molecules_26_ Bio-Potency and Molecular Docking Studies of Isolated Compounds from Grewia optiva J.R. Drumm. ex Burret
Vallianatou_2021_ACS.Chem.Neurosci__ Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain
Vieira_2021_Environ.Sci.Pollut.Res.Int__ Cholinesterases of marine fish: characterization and sensitivity towards specific chemicals
Vogel_2021_Sci.Total.Environ_773_145111 Enzymatic degradation of polyethylene terephthalate nanoplastics analyzed in real time by isothermal titration calorimetry
Wang_2021_Arch.Toxicol__ Ensemble machine learning to evaluate the in vivo acute oral toxicity and in vitro human acetylcholinesterase inhibitory activity of organophosphates
Wang_2021_Pharmaceutics_13_ Metabolism and Interspecies Variation of IMMH-010, a Programmed Cell Death Ligand 1 Inhibitor Prodrug
Wilkerson_2021_Pharmacol.Biochem.Behav__173192 Untapped endocannabinoid pharmacological targets: pipe dream or pipeline?
Wu_2021_Food.Chem_359_129960 Binding mechanism and functional evaluation of quercetin 3-rhamnoside on lipase
Wu_2021_Angew.Chem.Int.Ed.Engl__ Rational Design of Highly Selective Near-Infrared Two-Photon Fluorogenic Probe for Imaging Orthotopic Hepatocellular Carcinoma Chemotherapy
You_2021_Pest.Manag.Sci__ The overexpression and variant of a P450 gene CYP6G4 associated with propoxur resistance in the housefly, Musca domestica L
Yousafi_2021_Saudi.J.Biol.Sci_28_2197 In silico annotation of unreviewed acetylcholinesterase (AChE) in some lepidopteran insect pest species reveals the causes of insecticide resistance
Yusuf_2021_Foods_10_ Nutritional, Phytochemical Characteristics and In Vitro Effect on alpha-Amylase, alpha-Glucosidase, Lipase, and Cholinesterase Activities of 12 Coloured Carrot Varieties
Zhou_2021_Neuroreport_32_727 Poria cocos polysaccharide attenuates damage of nervus in Alzheimer's disease rat model induced by D-galactose and aluminum trichloride
Ahmad_2021_Molecules_26_ Biocomputational Screening of Natural Compounds against Acetylcholinesterase
Akintunde_2021_Biochem.Biophys.Rep_26_100999 Biogenic zinc-oxide nanoparticles of Moringa oleifera leaves abrogates rotenone induced neuroendocrine toxicity by regulation of oxidative stress and acetylcholinesterase activity
Alhawarri_2021_Molecules_26_ Antioxidant, Anti-Inflammatory, and Inhibition of Acetylcholinesterase Potentials of Cassia timoriensis DC. Flowers
Ali_2021_Int.Immunopharmacol_96_107729 Natural antioxidants enhance the power of physical and mental activities versus risk factors inducing progression of Alzheimer's disease in rats
Alqahtani_2021_Steroids_172_108857 Bioactive stigmastadienone from Isodon rugosus as potential anticholinesterase, alpha-glucosidase and COX\/LOX inhibitor: In-vitro and molecular docking studies
Bandoni_2021_Sci.Rep_11_9563 Cholinergic stimulation with pyridostigmine modulates a heart-spleen axis after acute myocardial infarction in spontaneous hypertensive rats
Borah_2021_3.Biotech_11_240 Analysing Curcuma caesia fractions and essential oil for neuroprotective potential against anxiety, depression, and amnesia
Cai_2021_Anal.Chem__ Capsulation of AuNCs with AIE Effect into Metal-Organic Framework for the Marriage of a Fluorescence and Colorimetric Biosensor to Detect Organophosphorus Pesticides
Calabretta_2021_Anal.Chem__ Ultrasensitive On-Field Luminescence Detection Using a Low-Cost Silicon Photomultiplier Device
Chiara_2021_Sci.Rep_11_9711 nAChRs gene expression and neuroinflammation in APPswe\/PS1dE9 transgenic mouse
Chopra_2021_Neurochem.Res__ N-Acetylcysteine Ameliorates Neurotoxic Effects of Manganese Intoxication in Rats: A Biochemical and Behavioral Study
Choubey_2021_Bioorg.Chem_111_104922 Design, synthesis, and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatment of Alzheimer's disease
Cruces-Solis_2021_FASEB.J_35_e21585 Altered theta and beta oscillatory synchrony in a genetic mouse model of pathological anxiety
Deprey_2021_Bioconjug.Chem__ HaloTag Forms an Intramolecular Disulfide
Forte_2021_J.Occup.Health_63_e12222 Pesticide exposure and adverse health effects associated with farmwork in Northern Thailand
Gao_2021_Nat.Microbiol__ A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase
Guo_2021_Nat.Prod.Res__1 Total synthesis of (-)-brazilane via a lipase-catalyzed desymmetrisation reaction
Gurdere_2021_In.Silico.Pharmacol_9_34 ADME properties, bioactivity and molecular docking studies of 4-amino-chalcone derivatives: new analogues for the treatment of Alzheimer, glaucoma and epileptic diseases
Her_2021_Br.J.Clin.Pharmacol__ Effect of CES1 genetic variation on enalapril steady-state pharmacokinetics and pharmacodynamics in healthy subjects
Herrera-Moreno_2021_Environ.Sci.Pollut.Res.Int__ Organophosphorus pesticide exposure biomarkers in a Mexican population
Kalyandurg_2021_Phytopathology__ Spray-induced gene silencing as a potential tool to control potato late blight disease
Kawai_2021_ChemSusChem__ Emerging Strategies in Polyethylene Terephthalate Hydrolase Research for Biorecycling
Kifle_2021_J.Environ.Public.Health_2021_6631721 Drug Repurposing Approach, Potential Drugs, and Novel Drug Targets for COVID-19 Treatment
Kumari_2021_Future.Microbiol__ The lipolytic activity of LipJ, a stress-induced enzyme, is regulated by its C-terminal adenylate cyclase domain
Lambre_2021_EFSA.J_19_e06561 Safety evaluation of the food enzyme triacylglycerol lipase from the genetically modified Aspergillus luchuensis strain FL100SC
Li_2021_Anal.Chem_93_7362 pH and Redox Dual-Response Disulfide Bond-Functionalized Red-Emitting Gold Nanoclusters for Monitoring the Contamination of Organophosphorus Pesticides in Foods
Li_2021_J.Agric.Food.Chem_69_5481 A Highly Efficient Three-Liquid-Phase-Based Enzymatic One-Pot Multistep Reaction System with Recoverable Enzymes for the Synthesis of Biodiesel
Lu_2021_Future.Med.Chem_13_1105 Synthesis and activity of miconazole derivatives as dual BChE\/IDO1 inhibitors for the treatment of Alzheimer's disease
Ma_2021_Insect.Mol.Biol__ Juvenile hormone regulates the reproductive diapause through Methoprene-tolerant gene in Galeruca daurica
Nutschel_2021_J.Chem.Inf.Model__ Promiscuous Esterases Counterintuitively Are Less Flexible than Specific Ones
Rambabu_2021_Clin.Toxicol.(Phila)__1 Acute phenthoate self-poisoning: a prospective case series
Robson_2021_Nat.Rev.Cardiol__ Blocking endothelial lipase raises HDL-C levels
Saxena_2021_Chem.Biol.Interact__109499 Conjugates of Human Serum Butyrylcholinesterase and Nerve Agents are Behaviorally Safe in Rhesus Macaques
Sunny_2021_Extremophiles__ IND-enzymes: a repository for hydrolytic enzymes derived from thermophilic and psychrophilic bacterial species with potential industrial usage
Trenaman_2021_BMC.Geriatr_21_297 An examination of three prescribing cascades in a cohort of older adults with dementia
Turkes_2021_J.Biomol.Struct.Dyn__1 Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and alpha-glucosidase inhibitors
Yan_2021_Sci.Total.Environ_785_147260 Characterization of a novel carboxylesterase with catalytic activity toward di(2-ethylhexyl) phthalate from a soil metagenomic library
Yang_2021_J.Obstet.Gynaecol.Res__ Dipeptidyl peptidase IV is required for endometrial carcinoma cell proliferation and tumorigenesis via the IL-6\/STAT3 pathway
Zhao_2021_Int.J.Biol.Macromol_183_811 Natural soluble epoxide hydrolase inhibitors from Alisma orientale and their potential mechanism with soluble epoxide hydrolase
Greene_2021_Biomacromolecules_22_1999 3D-Printed Enzyme-Embedded Plastics
Reisbeck_2021_Polymers.(Basel)_13_ Gram Scale Synthesis of Dual-Responsive Dendritic Polyglycerol Sulfate as Drug Delivery System
Richert_2021_Int.J.Biol.Macromol_176_226 Enzymatic degradation and biofilm formation during biodegradation of polylactide and polycaprolactone polymers in various environments
Araujo_2021_Environ.Sci.Pollut.Res.Int__ Effects of exposure to the UV-filter 4-MBC during Solea senegalensis metamorphosis
Barman_2021_Phytother.Res__ Nutmegs and wild nutmegs: An update on ethnomedicines, phytochemicals, pharmacology, and toxicity of the Myristicaceae species
Bazie_2021_Pathog.Immun_6_1 Plasma Extracellular Vesicle Subtypes May be Useful as Potential Biomarkers of Immune Activation in People With HIV
Cendrowska-Pinkosz_2021_J.Trace.Elem.Med.Biol_67_126777 The effect of the use of copper carbonate and copper nanoparticles in the diet of rats on the level of beta-amyloid and acetylcholinesterase in selected organs
Daly_2021_Biotechnol.Adv__107770 From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi
Della Vechia_2021_Pestic.Biochem.Physiol_175_104855 The role of detoxification enzymes in the susceptibility of Brevipalpus californicus exposed to acaricide and insecticide mixtures
Dissanayake_2021_Clin.Toxicol.(Phila)__1 Impaired neuromuscular function by conjoint actions of organophosphorus insecticide metabolites omethoate and cyclohexanol with implications for treatment of respiratory failure
El Yaagoubi_2021_J.Ethnopharmacol__114205 A review on Moroccan Thymus species: traditional uses, essential oils chemical composition and biological effects
Esfandi_2021_J.Food.Biochem__e13762 Antioxidant, pancreatic lipase, and alpha-amylase inhibitory properties of oat bran hydrolyzed proteins and peptides
Ferreira_2021_Eur.J.Med.Chem_221_113492 Dual-target compounds for Alzheimer's disease: Natural and synthetic AChE and BACE-1 dual-inhibitors and their structure-activity relationship (SAR)
Godfrey_2021_Brain.Res__147518 Enzymes of acetylcholine metabolism in the rat inferior colliculus
Guo_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1174_122722 A strategy to discover selective alpha-glucosidase\/acetylcholinesterase inhibitors from five function-similar citrus herbs through LC-Q-TOF-MS, bioassay and virtual screening
Hao_2021_J.Med.Entomol__ Transcriptome Analysis of Aedes albopictus (Diptera: Culicidae) Larvae Exposed With a Sublethal Dose of Haedoxan A
Jaouani_2021_Braz.J.Biol_82_e247035 Assessment of carbamazepine acute toxicity in the cockle Cerastoderma edule through chemical, physiological and biochemical tools
John_2021_Forensic.Sci.Int_323_110818 Evidence of exposure to organophosphorus toxicants by detection of the propionylated butyrylcholinesterase-derived nonapeptide-adduct as a novel biomarker
Kumar_2021_Curr.Med.Chem__ Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer's Disease
Lee_2021_Adv.Exp.Med.Biol_1187_23 Phospholipase Signaling in Breast Cancer
Li_2021_Data.Brief_36_107045 Data for the lipase catalyzed synthesis of cyano-containing multi-substituted indoles
Li_2021_Drug.Des.Devel.Ther_15_1883 Study on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology
Lopes_2021_Chem.Biol.Drug.Des__ Histamine H(3) receptor and cholinesterases as synergistic targets for cognitive decline: strategies to the rational design of multitarget ligands
Lumley_2021_Toxicol.Rep_8_896 Soman-induced toxicity, cholinesterase inhibition and neuropathology in adult male Gttingen minipigs
Mezeiova_2021_Bioorg.Med.Chem.Lett__128100 Huprine Y - tryptophan heterodimers with potential implication to Alzheimer's disease treatment
Mirzazadeh_2021_Arch.Pharm.(Weinheim)__e2000471 New quinoxalin-1,3,4-oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies
Mitic_2021_Expert.Opin.Drug.Metab.Toxicol__ Does the application of acetylcholinesterase inhibitors in the treatment of Alzheimer's disease lead to depression?
Niu_2021_Harmful.Algae_103_101996 Toxic effects of the dinoflagellate Karenia mikimotoi on zebrafish (Danio rerio) larval behavior
Obafemi_2021_Metab.Brain.Dis__ Combination of donepezil and gallic acid improves antioxidant status and cholinesterases activity in aluminum chloride-induced neurotoxicity in Wistar rats
Oyovwi_2021_Pestic.Biochem.Physiol_175_104833 Repeated endosulfan exposure induces changes in neurochemicals, decreases ATPase transmembrane ionic-pumps, and increased oxidative\/nitrosative stress in the brains of rats: Reversal by quercetin
Pattanashetti_2021_Indian.J.Pharmacol_53_50 Potential ameliorative effect of Cynodon dactylon (L.) pers on scopolamine-induced amnesia in rats: Restoration of cholinergic and antioxidant pathways
Rani_2021_J.Genet.Eng.Biotechnol_19_73 Study of lipase producing gene in wheat - an in silico approach
Reddy_2021_Environ.Res__111320 In-vitro evaluation of antioxidant and anticholinesterase activities of novel pyridine, quinoxaline and s-triazine derivatives
Rolim_2021_Pest.Manag.Sci__ Field-evolved resistance to beta-cyfluthrin in the boll weevil - detection and characterization
Saravanan_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_259_119856 Binding studies of known molecules with acetylcholinesterase and bovine serum albumin: A comparative view
Wei_2021_Pestic.Biochem.Physiol_175_104857 Novel amide derivatives containing an imidazo[1,2-a]pyridine moiety: Design, synthesis as potential nematicidal and antibacterial agents
Xia_2021_Ecotoxicol.Environ.Saf_218_112308 Developmental neurotoxicity of antimony (Sb) in the early life stages of zebrafish
Xu_2021_BMC.Genomics_22_350 Genome-wide analysis of the serine carboxypeptidase-like protein family in Triticum aestivum reveals TaSCPL184-6D is involved in abiotic stress response
Zhang_2021_Food.Res.Int_143_110242 UHPLC-QTOF-MS based metabolomics and biological activities of different parts of Eriobotrya japonica
Zilbeyaz_2021_Bioorg.Med.Chem_40_116194 Design and synthesis of garlic-related unsymmetrical thiosulfonates as potential Alzheimer's disease therapeutics: In vitro and in silico study
Ak_2021_Food.Chem.Toxicol_153_112268 Tanacetum vulgare L. (Tansy) as an effective bioresource with promising pharmacological effects from natural arsenal
Andersson_2021_Methods.Mol.Biol_2309_245 Structural Analysis of Strigolactone-Related Gene Products
Andrys_2021_Mol.Pharm__ Effect of Oxime Encapsulation on Acetylcholinesterase Reactivation: Pharmacokinetic Study of the Asoxime-Cucurbit[7]uril Complex in Mice Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry
Ateba_2021_Front.Pharmacol_12_641225 The Genus Eriosema (Fabaceae): From the Ethnopharmacology to an Evidence-Based Phytotherapeutic Perspective?
Bansal_2021_Plant.Cell.Rep__ Identification and molecular characterization of rice bran-specific lipases
Bas_2021_J.Food.Biochem__e13769 Lead nitrate and cadmium chloride induced hepatotoxicity and nephrotoxicity: Protective effects of sesamol on biochemical indices and pathological changes
Bauernfried_2021_Nat.Struct.Mol.Biol_28_333 DPP9 restrains NLRP1 activation
Bernabeu-Roda_2021_Methods.Mol.Biol_2309_91 Analyzing the Effect of Strigolactones on the Motility Behavior of Rhizobia
Beselia_2021_Neuroreport__ Modulation of prefrontal cortex function by basal forebrain cholinergic and GABAergic neurons at the behavioral and molecular level
Bingol_2021_Heliyon_7_e06986 Antidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) - profiling of phenolic compounds by LC-HRMS
Blanco-Ania_2021_Methods.Mol.Biol_2309_37 Synthesis of Analogs of Strigolactones and Evaluation of Their Stability in Solution
Braguy_2021_Methods.Mol.Biol_2309_201 A Protoplast-Based Bioassay to Quantify Strigolactone Activity in Arabidopsis Using StrigoQuant
Bray_2021_Sci.Total.Environ_778_146087 Sub-organism (acetylcholinesterase activity), population (survival) and chemical concentration responses reinforce mechanisms of antagonism associated with malathion toxicity
Bricher_2021_Front.Pharmacol_12_624895 The Cholinergic Drug Pyridostigmine Alleviates Inflammation During LPS-Induced Acute Respiratory Distress Syndrome
Cations_2021_Sci.Rep_11_10674 Using data linkage for national surveillance of clinical quality indicators for dementia care among Australian aged care users
Contreras-Aguilar_2021_Animal_15_100236 Changes in saliva biomarkers during a standardized increasing intensity field exercise test in endurance horses
de Saint Germain_2021_Methods.Mol.Biol_2309_219 Synthesis of Profluorescent Strigolactone Probes for Biochemical Studies
Dong_2021_BMJ.Open_11_e042765 Prognostic nomogram for the severity of acute organophosphate insecticide self-poisoning: a retrospective observational cohort study
Dudi-Venkata_2021_Colorectal.Dis__ PyRICo-Pilot - Pyridostigmine to reduce the duration of postoperative ileus after colorectal surgery - a phase II study
El-Ganainy_2021_Nanomedicine.(Lond)__ Galantamine nanoparticles outperform oral galantamine in an Alzheimer's rat model: pharmacokinetics and pharmacodynamics
Fiorilli_2021_Methods.Mol.Biol_2309_75 Evaluation of the Effect of Strigolactones and Synthetic Analogs on Fungi
Foo_2021_Methods.Mol.Biol_2309_179 Application of Strigolactones to Plant Roots to Influence Formation of Symbioses
Garlet_2021_Environ.Entomol__ Fitness Cost of Chlorpyrifos Resistance in Spodoptera frugiperda (Lepidoptera: Noctuidae) on Different Host Plants
Gogoi_2021_J.Food.Biochem__e13767 Chemical composition of Callistemon citrinus (Curtis) Skeels aerial part essential oil and its pharmacological applications, neurodegenerative inhibitory, and genotoxic efficiencies
Guillory_2021_Methods.Mol.Biol_2309_143 Methods for Medium-Scale Study of Biological Effects of Strigolactone-Like Molecules on the Moss Physcomitrium (Physcomitrella) patens
Guimaraes_2021_Sci.Total.Environ_779_146514 Multiple toxicity endpoints induced by carbon nanofibers in Amazon turtle juveniles: Outspreading warns about toxicological risks to reptiles
Hamiaux_2021_Methods.Mol.Biol_2309_233 The Use of Differential Scanning Fluorimetry to Assess Strigolactone Receptor Function
Huang_2021_Cancers.(Basel)_13_ DPP9: Comprehensive In Silico Analyses of Loss of Function Gene Variants and Associated Gene Expression Signatures in Human Hepatocellular Carcinoma
Imran_2021_Saudi.J.Biol.Sci_28_3031 In vitro examination of anti-parasitic, anti-Alzheimer, insecticidal and cytotoxic potential of Ajuga bracteosa Wallich leaves extracts
Ito_2021_Methods.Mol.Biol_2309_25 Chemical Synthesis of Triazole-Derived Suppressors of Strigolactone Functions
Jeong_2021_J.Microbiol.Biotechnol_31_ Increased mRNA stability and expression level of Croceibacter atlanticus lipase gene developed through molecular evolution process
Kandil_2021_Drug.Dev.Ind.Pharm__1 Intranasal galantamine\/chitosan complex nanoparticles elicit neuroprotection potentials in rat brains via antioxidant effect
Kshirsagar_2021_Neurotox.Res__ Hydrogen Sulfide Ameliorates Lipopolysaccharide-Induced Memory Impairment in Mice by Reducing Apoptosis, Oxidative, and Inflammatory Effects
Li_2021_Food.Sci.Nutr_9_2349 Extraction and purification of total flavonoids from Eupatorium lindleyanum DC. and evaluation of their antioxidant and enzyme inhibitory activities
Li_2021_J.Agric.Food.Chem_69_6087 Inorganic Recognizer-Assisted Homogeneous Electrochemiluminescence Determination of Organophosphorus Pesticides via Target-Controlled Emitter Release
Li_2021_Plant.J__ Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development
Li_2021_J.Pharm.Anal_11_183 A dual-signal sensor for the analysis of parathion-methyl using silver nanoparticles modified with graphitic carbon nitride
Li-Beisson_2021_New.Phytol__ The disassembly of lipid droplets in Chlamydomonas
Liu_2021_Int.J.Mol.Sci_22_ Association of TaD14-4D, a Gene Involved in Strigolactone Signaling, with Yield Contributing Traits in Wheat
Lu_2021_Food.Sci.Nutr_9_2402 The seed oil of Paeonia ludlowii ameliorates Abeta25-35-induced Alzheimer's disease in rats
Lyu_2021_BMJ.Open_11_e048453 Effect of antiamyloid-beta drugs on Alzheimer's disease: study protocol for a systematic review and meta-analysis
Makhaeva_2021_Bioorg.Chem_112_104974 Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment
Masurkar_2021_Drugs.Aging__ Antimuscarinic Cascade Across Individual Cholinesterase Inhibitors in Older Adults with Dementia
Missoum_2021_Methods.Mol.Biol_2290_215 Recombinant Protein Production and Purification Using Eukaryotic Cell Factories
Mota_2021_Neuroscientist__10738584211016409 Alzheimer's Disease: Innovative Therapeutic Approaches Based on Peptides and Nanoparticles
Muniz-Grijalvo_2021_Clin.Investig.Arterioscler_33 Suppl 2_56 Familial chylomicronemia and multifactorial chylomicronemia
Munoz_2021_Methods.Mol.Biol_2309_115 Methods for Phenotyping Shoot Branching and Testing Strigolactone Bioactivity for Shoot Branching in Arabidopsis and Pea
Nelson_2021_Plant.Physiol_185_1353 The mechanism of host-induced germination in root parasitic plants
Okazaki_2021_Planta_253_123 Strigolactone signaling inhibition increases adventitious shoot formation on internodal segments of ipecac
Pezzilli_2021_Pancreas__ Patients With Coronavirus Disease 2019 Interstitial Pneumonia Exhibit Pancreatic Hyperenzymemia and Not Acute Pancreatitis
Phachonpai_2021_Heliyon_7_e07003 Cognition enhancing effects of Clausena lansium (Lour.) peel extract attenuate chronic restraint stress-induced memory deficit in rats
Pineda-Martos_2021_Methods.Mol.Biol_2309_105 Chemotropic Assay for Testing Fungal Response to Strigolactones and Strigolactone-Like Compounds
Pospisil_2021_Methods.Mol.Biol_2309_31 Synthesis of Simple Strigolactone Mimics
Pouvreau_2021_Methods.Mol.Biol_2309_59 Strigolactone-Like Bioactivity via Parasitic Plant Germination Bioassay
Rolly_2021_Genes.(Basel)_12_ Insights into the Transcriptional Regulation of Branching Hormonal Signaling Pathways Genes under Drought Stress in Arabidopsis
Sridhar_2021_J.Biomol.Struct.Dyn__1 Synthesis, molecular modelling, in vitro and in vivo evaluation of conophylline inspired novel benzyloxy substituted indole glyoxylamides as potent pancreatic lipase inhibitors
Sanchez_2021_Methods.Mol.Biol_2309_191 Evaluation of Bioactivity of Strigolactone-Related Molecules by a Quantitative Luminometer Bioassay
Tan_2021_Drug.Des.Devel.Ther_15_1971 Inhibitory Effect of Lactococcus lactis subsp. lactis HFY14 on Diphenoxylate-Induced Constipation in Mice by Regulating the VIP-cAMP-PKA-AQP3 Signaling Pathway
Torabi_2021_Methods.Mol.Biol_2309_157 Controlled Assays for Phenotyping the Effects of Strigolactone-Like Molecules on Arbuscular Mycorrhiza Development
Ueno_2021_Methods.Mol.Biol_2309_13 Isolation and Identification of Naturally Occurring Strigolactones
Villaecija-Aguilar_2021_Methods.Mol.Biol_2309_129 Bioassays for the Effects of Strigolactones and Other Small Molecules on Root and Root Hair Development
Wang_2021_Genome.Med_13_83 An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
Xie_2021_Methods.Mol.Biol_2309_3 Evaluation and Quantification of Natural Strigolactones from Root Exudates
Xu_2021_J.Exp.Bot__ Strigolactones regulate sepal senescence in Arabidopsis
Zeng_2021_Food.Funct__ Rapid screening of lipase inhibitors in licorice extract by using porcine pancreatic lipase immobilized on Fe(3)O(4) magnetic nanoparticles
Zhang_2021_Chemosphere_281_130791 Effects of exogenous GR24 on biogas upgrading and nutrient removal by co-culturing microalgae with fungi under mixed LED light wavelengths
Alugubelly_2021_Neurotoxicol__ Persistent proteomic changes in glutamatergic and GABAergic signaling in the amygdala of adolescent rats exposed to chlorpyrifos as juveniles
Aman_2021_Crit.Care.Clin_37_673 Management of Organophosphorus Poisoning: Standard Treatment and Beyond
Askin_2021_Bioorg.Chem_113_105009 Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors
Ates_2021_Z.Naturforsch.C.J.Biosci__ New indane derivatives containing 2-hydrazinothiazole as potential acetylcholinesterase and monoamine oxidase-B inhibitors
Batschauer_2021_Chem.Biol.Interact__109532 Behavioral and neurochemical effects in mice after one-generation exposure to low doses of manganese: focus on offspring development
Bolognino_2021_ChemMedChem__ Synthesis and biological evaluation of dantrolene-like hydrazide and hydrazone analogues as multitarget agents for neurodegenerative diseases
Bothos_2021_J.Transl.Med_19_151 Clinical pharmacogenomics in action: design, assessment and implementation of a novel pharmacogenetic panel supporting drug selection for diseases of the central nervous system (CNS)
Bryant_2021_Science_372_ Stepwise pathogenic evolution of Mycobacterium abscessus
Calderini_2021_Chembiochem__ Simple plug-in synthetic step for the synthesis of (-)-camphor from renewable starting materials
Cayetano_2021_Bioresour.Technol_332_125014 Enhanced anaerobic digestion of waste-activated sludge via bioaugmentation strategy-Phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt2) analysis through hydrolytic enzymes and possible linkage to system performance
de ARC_2021_Bioprocess.Biosyst.Eng__ Computational and experimental analysis on the preferential selectivity of lipases for triglycerides in Licuri oil
Elshony_2021_Front.Neurosci_15_651471 Ameliorative Role of Cerium Oxide Nanoparticles Against Fipronil Impact on Brain Function, Oxidative Stress, and Apoptotic Cascades in Albino Rats
Fatiha_2021_Mol.Inform__ Identification of 1,2,4-triazolylthioethanone Scaffold for the Design of New Acetylcholinesterase Inhibitors
Feghhi_2021_Breast.Cancer.Res.Treat__ Bystander effects induced by electron beam-irradiated MCF-7 cells: a potential mechanism of therapy resistance
Gao_2021_World.J.Microbiol.Biotechnol_37_106 Improving the catalytic efficiency and substrate affinity of a novel esterase from marine Klebsiella aerogenes by random and site-directed mutation
Guo_2021_Sci.Total.Environ_789_147887 Combined toxicity of micro\/nano scale polystyrene plastics and ciprofloxacin to Corbicula fluminea in freshwater sediments
Hu_2021_Microb.Pathog__104969 MicroRNA-146a inhibits autophagy to maintain the intracellular survival of Burkholderia pseudomallei by targeting LIPA
Ibi_2021_Atherosclerosis__ Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile
Karatas_2021_Fish.Physiol.Biochem__ Effects of prolonged fasting on levels of metabolites, oxidative stress, immune-related gene expression, histopathology, and DNA damage in the liver and muscle tissues of rainbow trout (Oncorhynchus mykiss)
Kim_2021_J.Enzyme.Inhib.Med.Chem_36_1049 Inhibition of soluble epoxide hydrolase by phytochemical constituents of the root bark of Ulmus davidiana var. japonica
Koike_2021_Free.Radic.Biol.Med__ Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic beta-cell dysfunction and loss
Kumar_2021_Food.Chem_361_130031 Lipase - The fascinating dynamics of enzyme in seed storage and germination - A real challenge to pearl millet
Luis_2021_J.Nanobiotechnology_19_163 Ecotoxicity evaluation of polymeric nanoparticles loaded with ascorbic acid for fish nutrition in aquaculture
Masaryk_2021_Dalton.Trans__ Unexpected solution behaviour of ester-functionalized half-sandwich Ru(II) and Ir(III) complexes
Nieto_2021_Ultrason.Sonochem_75_105606 Ultrasound-assisted enzymatic synthesis of xylitol fatty acid esters in solvent-free conditions
Obeng_2021_J.Med.Chem_64_6523 Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery
Ogunsuyi_2021_Nutr.Neurosci__1 Dietary inclusions of Solanum vegetables mitigate aluminum-induced redox and inflammation-related neurotoxicity in Drosophila melanogaster model
Ontko_2021_Sci.Rep_11_9677 Cytochrome P450-epoxygenated fatty acids inhibit Muller glial inflammation
Orr_2021_Front.Behav.Neurosci_15_668589 Social Experience Regulates Endocannabinoids Modulation of Zebrafish Motor Behaviors
Ozkaya_2021_Acta.Chim.Slov_68_222 Protective Effects of 3-benzoyl-7-hydroxy Coumarin on Liver of Adult Rat Exposed to Aluminium Chloride
Pan_2021_Nature__ NF1 mutation drives neuronal activity-dependent initiation of optic glioma
Parsons_2021_Am.Soc.Clin.Oncol.Educ.Book_41_e90 Assessment and Management of Cognitive Symptoms in Patients With Brain Tumors
Roumeliotis_2021_Oxid.Med.Cell.Longev_2021_8817502 Association of rs11780592 Polymorphism in the Human Soluble Epoxide Hydrolase Gene (EPHX2) with Oxidized LDL and Mortality in Patients with Diabetic Chronic Kidney Disease
Saber_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1177_122759 Chemometric-enhanced metabolic profiling of five Pinus species using HPLC-MS\/MS spectrometry: Correlation to in vitro anti-aging, anti-Alzheimer and antidiabetic activities
Taha_2021_Environ.Sci.Pollut.Res.Int__ Alteration in antioxidant status in slow and fast alleles of EPHX1 gene polymorphisms among wood workers
Tang_2021_ChemMedChem__ Novel pyridine-containing sultones: Structure-activity relationship and biological evaluation as selective AChE inhibitors for the treatment of Alzheimer's disease
Valk_2021_Clin.Pharmacokinet__ Etomidate and its Analogs: A Review of Pharmacokinetics and Pharmacodynamics
Wu_2021_J.Sep.Sci__ Absolute protein assay for the simultaneous quantification of two epoxide hydrolases in rats by mass spectrometry-based targeted proteomics
Yan_2021_Appl.Microbiol.Biotechnol__ Synergistic biodegradation of poly(ethylene terephthalate) using Microbacterium oleivorans and Thermobifida fusca cutinase
Zhang_2021_J.Biol.Chem__100841 Active site architecture of an acetyl xylan esterase indicates a novel cold adaptation strategy
Zhu_2021_Pharmacol.Biochem.Behav__173209 Donepezil prevents morphine tolerance by regulating N-methyl-d-aspartate receptor, protein kinase C and CaM-dependent kinase II expression in rats
Boes_2021_Membranes.(Basel)_11_ Peripheral Membrane Proteins: Promising Therapeutic Targets across Domains of Life
Khamphukdee_2021_Molecules_26_ Antidementia Effects of Alternanthera philoxeroides in Ovariectomized Mice Supported by NMR-Based Metabolomic Analysis
Kim_2021_Molecules_26_ Neuroprotective Effect and Antioxidant Potency of Fermented Cultured Wild Ginseng Root Extracts of Panax ginseng C.A. Meyer in Mice
Les_2021_Biology.(Basel)_10_ Jasonia glutinosa (L.) DC., a Traditional Herbal Tea, Exerts Antioxidant and Neuroprotective Properties in Different In Vitro and In Vivo Systems
Liu_2021_Biology.(Basel)_10_ Enhancement of Fear Extinction Memory and Resistance to Age-Related Cognitive Decline in Butyrylcholinesterase Knockout Mice and (R)-Bambuterol Treated Mice
Mangmool_2021_Molecules_26_ Antioxidant and Anticholinesterase Activities of Extracts and Phytochemicals of Syzygium antisepticum Leaves
Martin-Reina_2021_Int.J.Environ.Res.Public.Health_18_ Adverse Health Effects in Women Farmers Indirectly Exposed to Pesticides
Miziak_2021_Pharmaceuticals.(Basel)_14_ Some Candidate Drugs for Pharmacotherapy of Alzheimer's Disease
Ogungbemi_2021_Toxics_9_ Assessing Combined Effects for Mixtures of Similar and Dissimilar Acting Neuroactive Substances on Zebrafish Embryo Movement
Panamito_2021_Molecules_26_ Chemical Composition and Anticholinesterase Activity of the Essential Oil of Leaves and Flowers from the Ecuadorian Plant Lepechinia paniculata (Kunth) Epling
Parvez_2021_Drug.Metab.Dispos__ Quantitative investigation of irinotecan metabolism, transport and gut microbiome activation
Schepetkin_2021_Biomolecules_11_ Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential
Song_2021_Cells_10_ TSPO Expression Modulatory Effect of Acetylcholinesterase Inhibitor in the Ischemic Stroke Rat Model
Turecky_2021_Vnitr.Lek_67_4 Serum butyrylcholinesterase\/HDL-cholesterol ratio and atherogenic index of plasma in patients with fatty liver disease
Yainna_2021_Insects_12_ Geographic Monitoring of Insecticide Resistance Mutations in Native and Invasive Populations of the Fall Armyworm
Zengin_2021_Antioxidants.(Basel)_10_2 Chemical Composition and Biological Properties of Two Jatropha Species: Different Parts and Different Extraction Methods
Zhang_2021_Foods_10_ The UHPLC-QTOF-MS Phenolic Profiling and Activity of Cydonia oblonga Mill. Reveals a Promising Nutraceutical Potential
Abdollahdokht_2021_Environ.Sci.Pollut.Res.Int__ Pesticide exposure and related health problems among farmworkers' children: a case-control study in southeast Iran
Aguirre-Rojas_2021_Sci.Rep_11_11448 Comparative analyses of transcriptional responses of Dectes texanus LeConte (Coleoptera: Cerambycidae) larvae fed on three different host plants and artificial diet
Anantayanon_2021_Gene__145745 Significance of two intracellular triacylglycerol lipases of Aspergillus oryzae in lipid mobilization: A perspective in industrial implication for microbial lipid production
Britto_2021_Pest.Manag.Sci__ Potential of Ficus carica extracts against Euschistus heros: toxicity of major active compounds and selectivity against beneficial insects
Burrows_2021_Genes.Brain.Behav__e12757 Mice with an autism-associated R451C mutation in neuroligin-3 show a cautious but accurate response style in touchscreen attention tasks
Cheon_2021_Nanomaterials.(Basel)_11_ Highly Sensitive Fluorescent Detection of Acetylcholine Based on the Enhanced Peroxidase-Like Activity of Histidine Coated Magnetic Nanoparticles
Courties_2021_Sci.Rep_11_11886 Regulation of the acetylcholine\/alpha7nAChR anti-inflammatory pathway in COVID-19 patients
de Paula_2021_Aquat.Toxicol_237_105874 Effects of copper on an omnivorous (Astyanax altiparanae) and a carnivorous fish (Hoplias malabaricus): A comparative approach
Devidas_2021_Eur.J.Pharmacol__174234 Amelioration of cognitive deficit in zebrafish by an undescribed anthraquinone from Juglans regia L.: An in-silico, in-vitro and in-vivo approach
Erdogan_2021_Arch.Pharm.(Weinheim)__e2100113 Synthesis and biological evaluation of some 1-naphthol derivatives as antioxidants, acetylcholinesterase, and carbonic anhydrase inhibitors
Ertas_2021_Chem.Biodivers__ Phytochemical fingerprints and bioactivities of Ripe Disseminules (Fruit-Seeds) of seventeen Gundelia (Kenger-kereng dikeni) Species from Anatolia with Chemometric Approach
Erukainure_2021_Front.Pharmacol_12_610835 Turbina oblongata Protects Against Oxidative Cardiotoxicity by Suppressing Lipid Dysmetabolism and Modulating Cardiometabolic Activities Linked to Cardiac Dysfunctions
Ghosh_2021_Front.Mol.Neurosci_14_678510 Cannabinoid Signaling in Auditory Function and Development
He_2021_Bioprocess.Biosyst.Eng__ High specific immobilization of His-tagged recombinant Microbacterium esterase by Ni-NTA magnetic chitosan microspheres for efficient synthesis of key chiral intermediate of d-biotin
Jamora_2021_Neurol.Sci__ Acetylcholinesterase inhibitor responsive myasthenia in a Filipino male with X-linked recessive spinal and bulbar muscular atrophy
Johan_2021_Colloids.Surf.B.Biointerfaces_205_111882 An integrated overview of bacterial carboxylesterase: Structure, function and biocatalytic applications
Kadir_2021_Bioorg.Chem_113_105032 Fatty acid composition, enzyme inhibitory effect, antioxidant and anticancer activity of extract from Saponaria prostrata WILLD. subsp. anatolica HEDGE
Le Du-Carree_2021_Sci.Total.Environ_784_147162 Immunological and metabolic effects of acute sublethal exposure to glyphosate or glyphosate-based herbicides on juvenile rainbow trout, Oncorhynchus mykiss
Li_2021_Stem.Cell.Res_53_102313 A non-integrated iPSC line (SDQLCHi042-A) from a boy suffering from familial combined hyperlipidemia with compound heterozygous mutations of lipoprotein lipase gene
Linari_2021_J.Vet.Diagn.Invest__10406387211021345 Evaluation of 1,2-O-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin) ester (DGGR) and 1,2-diglyceride lipase assays in dogs with naturally occurring hypercortisolism
Mavangira_2021_Antioxidants.(Basel)_10_ Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis
Morisseau_2021_Int.J.Mol.Sci_22_ Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues
Nana_2021_J.Hazard.Mater_415_125752 Colorimetric detection of chlorpyrifos in peach based on cobalt-graphene nanohybrid with excellent oxidase-like activity and reusability
Naseem_2021_Exp.Brain.Res__ Behavioural tagging: Effect of novelty exploration on plasticity related molecular signatures
Oh_2021_J.Microbiol.Biotechnol__ Chromenone Derivatives as Monoamine Oxidase Inhibitors from Marine-Derived MAR4 Clade Streptomyces sp. CNQ-031
Omeiza_2021_Brain.Behav__e2227 Melatonin salvages lead-induced neuro-cognitive shutdown, anxiety, and depressive-like symptoms via oxido-inflammatory and cholinergic mechanisms
Perrier_2021_Commun.Biol_4_665 Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
Qiu_2021_J.Basic.Microbiol__ Microbial halophilic lipases: A review
Rangel_2021_PLoS.One_16_e0251556 Multicomponent carbohydrase system from Trichoderma reesei: A toolbox to address complexity of cell walls of plant substrates in animal feed
Rompicherla_2021_Naunyn.Schmiedebergs.Arch.Pharmacol__ Pharmacokinetic and pharmacodynamic evaluation of nasal liposome and nanoparticle based rivastigmine formulations in acute and chronic models of Alzheimer's disease
Saidani_2021_Mar.Pollut.Bull_169_112556 Toxicity assessment of organophosphorus in Ruditapes decussatus via physiological, chemical and biochemical determination: A case study with the compounds gamma-oximo- and gamma-amino-phosphonates and phosphine oxides
Santos_2021_Rev.Bras.Parasitol.Vet_30_e002221 Effects of essential oils on native and recombinant acetylcholinesterases of Rhipicephalus microplus
Sinan_2021_Chem.Biodivers__2 A prospective of multiple biopharmaceutical activities of procyanidins-rich Uapaca togoensis Pax extracts: HPLC-ESI-TOF-MS coupled with bioinformatics analysis
Svob_2021_Pharmgenomics.Pers.Med_14_631 Personalizing the Care and Treatment of Alzheimer's Disease: An Overview
Takeo_2021_ACS.Chem.Neurosci__ Mass Spectrometric Enzyme Histochemistry for Choline Acetyltransferase Reveals De Novo Acetylcholine Synthesis in Rodent Brain and Spinal Cord
Tanaka_2021_J.UOEH_43_197 The Role of Brain Methamidophos in Acephate Poisoning in Mice
Thandar_2021_J.UOEH_43_173 Serum High-sensitivity C-reactive Protein Level and Corrected QT Interval in Agricultural Workers in Myanmar Exposed to Chronic Occupational Organophosphate Pesticides
Totsingan_2021_Molecules_26_ Structure-Activity Relationship Assessment of Sophorolipid Ester Derivatives against Model Bacteria Strains
Varshney_2021_Mol.Biol.Rep__ Ang(1-7) exerts Nrf2-mediated neuroprotection against amyloid beta-induced cognitive deficits in rodents
Vig_2021_J.Appl.Microbiol__ Neuroprotective effects of quercetin produced by an endophytic fungus Nigrospora oryzae isolated from Tinospora cordifolia
Yadav_2021_Clin.Chim.Acta_520_34 Acute aluminum phosphide poisoning: The menace of phosphine exposure
Yang_2021_Front.Pharmacol_12_647481 Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice
Yang_2021_Fitoterapia_153_104948 A norbisabolane and an arabitol benzoate from Talaromyces marneffei, an endophytic fungus of Epilobium angustifolium
Yoon_2021_Biol.Psychiatry__ cAMP Signaling-Mediated Phosphorylation of Diacylglycerol Lipase alpha Regulates Interaction With Ankyrin-G and Dendritic Spine Morphology
Zhang_2021_Nutr.Clin.Pract__ Evaluation of the effect of high protein supply on diaphragm atrophy in critically ill patients receiving prolonged mechanical ventilation
Zhao_2021_Chin.J.Nat.Med_19_454 Bufotenine and its derivatives: synthesis, analgesic effects identification and computational target prediction
Al-Kuraishy_2021_Front.Cardiovasc.Med_8_644095 COVID-19 in Relation to Hyperglycemia and Diabetes Mellitus
Bursal_2021_Biophys.Chem_277_106629 Enzyme inhibitory function and phytochemical profile of Inula discoidea using in vitro and in silico methods
Cakmak_2021_Liver.Int_41_905 Chanarin-Dorfman Syndrome: A comprehensive review
Chen_2021_Front.Mol.Biosci_8_656440 Regulation of Dynamic Protein S-Acylation
Chowdhury_2021_Eur.J.Med.Chem_222_113541 Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Abeta antiaggregant
Chrzanowski-Smith_2021_Exp.Physiol_106_1208 Resting skeletal muscle PNPLA2 (ATGL) and CPT1B are associated with peak fat oxidation rates in men and women but do not explain observed sex differences
Edres_2021_Environ.Sci.Pollut.Res.Int__ The potential neuroprotective effect of allicin and melatonin in acrylamide-induced brain damage in rats
Goger_2021_Turk.J.Chem_45_387 Phytochemical characterisation of Phlomis linearis Boiss. & Bal and screening for anticholinesterase, antiamylase, antimicrobial, and cytotoxic properties
Haris_2021_Acc.Chem.Res__ Seeking Illumination: The Path to Chemiluminescent 1,2-Dioxetanes for Quantitative Measurements and In Vivo Imaging
Ilijin_2021_An.Acad.Bras.Cienc_93_e20190118 Biological effects of chronic exposure of Blaptica dubia (Blattodea: Blaberidae) nymphs to static and extremely low frequency magnetic fields
Innocenzi_2021_J.Funct.Morphol.Kinesiol_6_ Aerobic Exercise Induces Alternative Splicing of Neurexins in Frontal Cortex
Jaumotte_2021_Neurobiol.Dis__105422 Ciclesonide activates glucocorticoid signaling in neonatal rat lung but does not trigger adverse effects in the cortex and cerebellum
Jiang_2021_Int.J.Dermatol__ Two cases of Chanarin-Dorfman syndrome with novel and recurrent mutations in the ABHD5 gene
Khairy_2021_Environ.Sci.Process.Impacts__ Sea urchin-like calcium borate microspheres and synergistic action with cholinesterase-inhibiting insecticides for ecofriendly Spodoptera littoralis control
Koodalingam_2021_Pestic.Biochem.Physiol_176_104882 Studies on biochemical and synergistic effects of immunosuppressive concentration of imidacloprid with Beauveria bassiana and Metarhizium anisopliae for enhancement of virulence against vector mosquito Culex quinquefasciatus
Kurt-Celep_2021_Food.Chem.Toxicol__112330 Comprehensive evaluation of two Astragalus species (A. campylosema and A. hirsutus) based on biological, toxicological properties and chemical profiling
Li_2021_Front.Oncol_11_679816 Antidiabetic Agent DPP-4i Facilitates Murine Breast Cancer Metastasis by Oncogenic ROS-NRF2-HO-1 Axis via a Positive NRF2-HO-1 Feedback Loop
Liakath-Ali_2021_Front.Mol.Neurosci_14_659681 The Perils of Navigating Activity-Dependent Alternative Splicing of Neurexins
Luan_2021_Ecotoxicol.Environ.Saf_220_112398 Toxicologic effect and transcriptome analysis for short-term orally dosed enrofloxacin combined with two veterinary antimicrobials on rat liver
MacCormack_2021_Front.Bioeng.Biotechnol_9_689933 Boron Oxide Nanoparticles Exhibit Minor, Species-Specific Acute Toxicity to North-Temperate and Amazonian Freshwater Fishes
Melefa_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109108 Imidazole antifungal drug clotrimazole alters the behavior, brain acetylcholinesterase and oxidative stress biomarkers in African catfish Clarias gariepinus (Burchell 1822)
Moo_2021_Clin.Ther__ Unexpected Findings During Double-blind Discontinuation of Acetylcholinesterase Inhibitor Medications
Naughton_2021_Neurosci.Insights_16_26331055211020289 The Carbamate, Physostigmine does not Impair Axonal Transport in Rat Cortical Neurons
Nazari_2021_EXCLI.J_20_907 Novel 1,2,4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation
Ndongo_2021_Arch.Pharm.(Weinheim)__e2100150 Microsequential injection analysis\/lab-on-valve system for the automatic evaluation of acetylcholinesterase inhibitors
Nephale_2021_Environ.Sci.Pollut.Res.Int__ Use of biomarkers in monitoring pollution status of urban rivers, Limpopo, South Africa
Nett_2021_Proc.Natl.Acad.Sci.U.S.A_118_ A metabolic regulon reveals early and late acting enzymes in neuroactive Lycopodium alkaloid biosynthesis
Niu_2021_Anal.Chem__ Nitrogen-Doped Graphdiyne as a Robust Electrochemical Biosensing Platform for Ultrasensitive Detection of Environmental Pollutants
Rani_2021_Bioorg.Chem_114_105053 1H-1,2,3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice brain cells
Rubio-Vargas_2021_Environ.Toxicol.Pharmacol_87_103682 Exposure to pollutants present in Iguacu River Southern Brazil affect the health of Oreochromis niloticus (Linnaeus, 1758): Assessment histological, genotoxic and biochemical
Sandoval-Gio_2021_Bull.Environ.Contam.Toxicol__ Effect of Benzophenone-3 to Acetylcholinesterase and Antioxidant System in Zebrafish (Danio rerio) Embryos
Serrano_2021_J.Acad.Consult.Liaison.Psychiatry_62_285 The Use of Physostigmine in the Diagnosis and Treatment of Anticholinergic Toxicity After Olanzapine Overdose: Literature Review and Case Report
Shah_2021_J.Tradit.Chin.Med_41_349 Efficacy of Silene arenosa extract on acetylcholinesterase in Bungarus sindanus (krait) venom
Sharma_2021_Biol.Trace.Elem.Res__ Distribution of Fluoride in Plasma, Brain, and Bones and Associated Oxidative Damage After Induced Chronic Fluorosis in Wistar Rats
Sharma_2021_Drug.Metab.Pers.Ther__ Consumption of Ashtanga Ghrita (clarified cow butter added with herb extracts) improves cognitive dysfunction induced by scopolamine in rats via regulation of acetylcholinesterase activity and oxidative stress
Shim_2021_Front.Aging.Neurosci_13_665400 Decreased Exosomal Acetylcholinesterase Activity in the Plasma of Patients With Parkinson's Disease
Sinan_2021_J.Pharm.Biomed.Anal_203_114184 NMR and LC-MS(n) coupled with pharmacological network analysis for the assessment of phytochemical content and biopharmaceutical potential of Carapa procera extracts
Tavian_2021_Eur.J.Transl.Myol__ Recurrent N209* ABHD5 mutation in two unreported families with Chanarin Dorfman Syndrome
Xu_2021_Nat.Chem__ Catalytic reductive desymmetrization of malonic esters
Zhao_2021_J.Dermatol.Sci_102_7 Circular RNA circ_0079593 enhances malignant melanoma progression by the regulation of the miR-573\/ABHD2 axis
Alzweiri_2021_Bioorg.Med.Chem.Lett__128205 The structural simplification of lysergic acid as a natural lead for synthesizing novel anti-Alzheimer agents
Ashok_2021_Bioorg.Med.Chem.Lett__128212 Design, synthesis and biological evaluation of novel deoxyvasicinone-indole as multi-target agents for Alzheimer's disease
Avolio_2021_Vet.Anim.Sci_13_100178 Retrospective data analysis of animal poisoning events in Liguria
Barmpa_2021_J.Inorg.Biochem_222_111507 Nickel(II)-meclofenamate complexes: Structure, in vitro and in silico DNA- and albumin-binding studies, antioxidant and anticholinergic activity
Ben Salah_2021_Bioprocess.Biosyst.Eng__ Green Roccella phycopsis Ach. mediated silver nanoparticles: synthesis, characterization, phenolic content, antioxidant, antibacterial and anti-acetylcholinesterase capacities
Chebii_2021_J.Mol.Evol__ Genome Scan for Variable Genes Involved in Environmental Adaptations of Nubian Ibex
Contreras-Aguilar_2021_Vet.J_273_105679 Changes in saliva analytes during pregnancy, farrowing and lactation in sows: A sialochemistry approach
Erukainure_2021_Food.Chem.Toxicol_154_112335 Cola nitida infusion modulates cardiometabolic activities linked to cardiomyopathy in diabetic rats
Erukainure_2021_Amino.Acids_53_1135 L-leucine stimulation of glucose uptake and utilization involves modulation of glucose - lipid metabolic switch and improved bioenergetic homeostasis in isolated rat psoas muscle ex vivo
Frei_2021_eNeuro__ Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism
Guerra_2021_Arch.Environ.Contam.Toxicol__ Biochemical and Behavioral Responses in Zebrafish Exposed to Imidacloprid Oxidative Damage and Antioxidant Responses
Gundlach_2021_Sci.Total.Environ_792_148368 Effects of the antidepressant mirtazapine on the swimming behaviour and gene expression rate of Danio rerio embryos - Is the sedating effect seen in humans also evident for fish?
He_2021_Anal.Chem__ Bifunctional Moderator-Powered Ratiometric Electrochemiluminescence Enzymatic Biosensors for Detecting Organophosphorus Pesticides Based on Dual-Signal Combined Nanoprobes
Herrera-Acevedo_2021_Mol.Divers__ Machine learning models to select potential inhibitors of acetylcholinesterase activity from SistematX: a natural products database
Honda_2021_Drug.Metab.Dispos__ Differences in hydrolase activities in the liver and small intestine between marmosets and humans
Kang_2021_ACS.Omega_6_14963 Acetylcholine Detection Based on pH-Sensitive Liposomes
Kitagawa_2021_J.Enzyme.Inhib.Med.Chem_36_1370 Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators
Kulakova_2021_Biomed.Khim_67_300 [Molecular mechanism of chromogenic substrate hydrolysis in the active site of human carboxylesterase-1]
Manikandan_2021_Int.J.Fertil.Steril_15_219 Assessment of Organophosphate Pesticides Exposure in Men with Idiopathic Abnormal Semen Analysis: A Cross-Sectional Pilot Study
Maslennikov_2021_World.J.Hepatol_13_557 Gut dysbiosis is associated with poorer long-term prognosis in cirrhosis
Modoni_2021_Clin.Neurophysiol_132_1845 Cholinergic hyperactivity in patients with myasthenia gravis with MuSK antibodies: A neurophysiological study
Moleda_2021_Bioorg.Med.Chem_42_116269 Clicking fragment leads to novel dual-binding cholinesterase inhibitors
Ortiz_2021_Arq.Neuropsiquiatr_79_283 Language impairment in the moderate stage of dementia due to Alzheimer's disease
Ortiz-Delgado_2021_Environ.Toxicol__ Toxicity of malathion during Senegalese sole, Solea senegalensis larval development and metamorphosis: Histopathological disorders and effects on type B esterases and CYP1A enzymatic systems
Qasim_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109112 Host-pathogen interaction between Asian citrus psyllid and entomopathogenic fungus (Cordyceps fumosorosea) is regulated by modulations in gene expression, enzymatic activity and HLB-bacterial population of the host
Riaz_2021_Bioorg.Chem_114_105069 Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone
Saleem_2021_Food.Chem.Toxicol__112348 A comprehensive phytochemical, biological, toxicological and molecular docking evaluation of Suaeda fruticosa (L.) Forssk.: An edible halophyte medicinal plant
Saleem_2021_Front.Pharmacol_12_664832 Pharmacological Screening of Viola odorata L. for Memory-Enhancing Effect via Modulation of Oxidative Stress and Inflammatory Biomarkers
Salih_2021_Cogn.Neuropsychiatry__1 Imagine that: cholinesterase inhibitor treatment of complex visual hallucinations of unknown aetiology
Schwenk_2021_J.Physiol_599_2639 Building of AMPA-type glutamate receptors in the endoplasmic reticulum and its implication for excitatory neurotransmission
Selonen_2021_Environ.Res__111495 Exploring the impacts of microplastics and associated chemicals in the terrestrial environment - Exposure of soil invertebrates to tire particles
Srancikova_2021_Andrologia__e14153 The effects of testosterone on gene expression of cell-adhesion molecules and scaffolding proteins: The role of sex in early development
Takenaka_2021_Int.J.Food.Microbiol_353_109299 Identification and characterization of extracellular enzymes secreted by Aspergillus spp. involved in lipolysis and lipid-antioxidation during katsuobushi fermentation and ripening
Yun_2021_J.Enzyme.Inhib.Med.Chem_36_1346 Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer's disease agents
Zhang_2021_Front.Pharmacol_12_632757 The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area
Zhang_2021_Chem.Biol.Drug.Des__ Phthalimide-(N-alkylbenzylamine) cysteamide hybrids as multifunctional agents against Alzheimer's disease: Design, synthesis and biological evaluation
Agami_2021_Anal.Bioanal.Chem__ LC-MS bioanalysis of targeted nasal galantamine bound chitosan nanoparticles in rats' brain homogenate and plasma
Aly_2021_IBRO.Neurosci.Rep_10_109 Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: A systematic review
Athar_2021_Mol.Biol.Rep__ Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease
Badjic_2021_Chemistry__ Molecular Recognition of Nerve Agents and Their Organophosphorus Surrogates: Toward Supramolecular Scavengers and Catalysts
Bakker_2021_Drugs.R.D__ Safety and Pharmacokinetics of HTL0018318, a Novel M(1) Receptor Agonist, Given in Combination with Donepezil at Steady State: A Randomized Trial in Healthy Elderly Subjects
Butler_2021_Contemp.Clin.Trials__106488 Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus cholinesterase inhibition to reduce neurologic decline in Alzheimer's
Chen_2021_Chem.Sci_12_5202 Synergistic enhancement of the emergency treatment effect of organophosphate poisoning by a supramolecular strategy
Cioffi_2021_Environ.Sci.Technol__ Office Paper-Based Electrochemical Strips for Organophosphorus Pesticide Monitoring in Agricultural Soil
ElDin_2021_Biosens.Bioelectron_190_113439 Microfabricated potentiometric sensor for personalized methacholine challenge tests during the COVID-19 pandemic
Fakhereddin_2021_Arh.Hig.Rada.Toksikol_72_164 Pro-oxidant potency of clothianidin in rainbow trout
Ghafour-Boroujerdi_2021_Life.Sci__119766 Investigation of alpha-lipoic acid effect on memory impairment considering strain-dependent differences in mice
Habib_2021_Food.Chem_364_130415 Inhibitory effects of honey from arid land on some enzymes and protein damage
He_2021_Environ.Pollut_287_117649 Toxicity of gabapentin-lactam on the early developmental stage of zebrafish (Danio rerio)
Hull_2021_Curr.Opin.Plant.Biol_62_102071 Conditioning plants for arbuscular mycorrhizal symbiosis through DWARF14-LIKE signalling
Kim_2021_Medicine.(Baltimore)_100_e26457 Diagnostic yields and clinical features of ocular myasthenia gravis
Klatka_2021_Ann.Agric.Environ.Med_28_358 Severe carbamates intoxication of 43-year-old farmer - case report
Koca_2021_Mol.Divers__ New benzamide derivatives and their nicotinamide\/cinnamamide analogs as cholinesterase inhibitors
Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693 Release of protein-bound nerve agents by excess fluoride from whole blood: GC-MS\/MS method development, validation, and application to a real-life denatured blood sample
Leonard_2021_J.Food.Sci__ Effect of extrusion technology on hempseed (Cannabis sativa L.) oil cake: Polyphenol profile and biological activities
Li_2021_Appl.Biochem.Biotechnol__ Enhanced Secretory Expression and Surface Display Level of Bombyx mori Acetylcholinesterase 2 by Pichia pastoris Based on Codon Optimization Strategy for Pesticides Setection
Lleo_2021_Alzheimers.Res.Ther_13_119 VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome
Mandour_2021_J.Mol.Histol__ Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid hesperidin
Maxwell_2021_J.Clin.Psychopharmacol__ Prolonged Paralysis After Electroconvulsive Therapy Due to Butyrylcholinesterase Gene Mutation
Min_2021_Bioresour.Technol_337_125394 Improving the organic solvent resistance of lipase a from Bacillus subtilis in water-ethanol solvent through rational surface engineering
Orondo_2021_Parasit.Vectors_14_335 Insecticide resistance status of Anopheles arabiensis in irrigated and non-irrigated areas in western Kenya
Polopalli_2021_World.J.Biol.Psychiatry__1 A prognostic study on the effect of post-traumatic stress disorder on cerebral ischaemia reperfusion-induced stroke
Samson_2021_Brain.Res__147565 The impairment of motor coordination following chronic carbamazepine-levetiracetam adjunctive treatment with evidence of corticocerebellar toxicity in male Wistar rats
Sharma_2021_J.Basic.Clin.Physiol.Pharmacol__ Behavioral and biochemical investigations to explore the efficacy of quercetin and folacin in experimental diabetes induced vascular endothelium dysfunction and associated dementia in rats
Soma_2021_Neurobiol.Learn.Mem_183_107484 Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory
Song_2021_Chem.Biol.Interact__109566 Carboxylesterase inhibitors from clinically available medicines and their impact on drug metabolism
Tassone_2021_Mov.Disord__ Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia
Tripathi_2021_Drug.Dev.Res__ Comprehensive investigations for a potential natural prophylaxis-A cellular and murine model for apple cider vinegar against hydrogen peroxide and scopolamine induced oxidative stress
Ueda_2021_Biosci.Biotechnol.Biochem__ Cutinase-like biodegradable plastic-degrading enzymes from phylloplane yeasts have cutinase activity
Wu_2021_Clin.Transl.Med_11_e428 Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum-hippocampus cholinergic pathway
Xu_2021_Anal.Chem__ Construction of Peroxidase-like Metal-Organic Frameworks in TiO(2) Nanochannels: Robust Free-Standing Membranes for Diverse Target Sensing
Yu_2021_Analyst__ A photoelectrochemical sensor based on an acetylcholinesterase-CdS\/ZnO-modified extended-gate field-effect transistor for glyphosate detection
Zandona_2021_Arch.Toxicol__ Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes
Zeng_2021_Plant.J__ The immune components EDS1 and PAD4 are required for cell death caused by overaccumulation of ceramides in Arabidopsis
Zhang_2021_Medicine.(Baltimore)_100_e26462 A simple noninvasive model to predict significant fibrosis in children with chronic hepatitis B
Aarsland_2021_Nat.Rev.Dis.Primers_7_47 Parkinson disease-associated cognitive impairment
Adib_2021_Saudi.J.Biol.Sci_28_3893 Cholinesterase inhibitory activity of tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia: In vitro and in silico studies targeting management of Alzheimer's disease
Ahsan_2021_Inflammopharmacology__ Pharmacological support to anti-arthritic prospective of physostigmine: a new approach
Al-Emam_2021_Toxicol.Rep_8_1226 Butyryl-cholinesterase deficiency: A case report of delayed recovery after general anaesthesia
Amala_2021_Molecules_26_ Bioefficacy of Epaltes divaricata (L.) n-Hexane Extracts and Their Major Metabolites against the Lepidopteran Pests Spodoptera litura (fab.) and Dengue Mosquito Aedes aegypti (Linn.)
Andrejcakova_2021_Saudi.J.Biol.Sci_28_3789 Dietary flaxseed's protective effects on body tissues of mice after oral exposure to xylene
Anwar_2021_Antioxidants.(Basel)_10_ A Leaf Extract of Harrisonia abyssinica Ameliorates Neurobehavioral, Histological and Biochemical Changes in the Hippocampus of Rats with Aluminum Chloride-Induced Alzheimer's Disease
Asada_2021_Biochem.Biophys.Res.Commun_549_105 Secretory production of a camelid single-domain antibody (VHH, nanobody) by the Serratia marcescens Lip system in Escherichia coli
Bajaj_2021_Brain.Res.Bull__ The role of endocannabinoid pathway in the neuropathology of Alzheimer's disease: Can the inhibitors of MAGL and FAAH prove to be potential therapeutic targets against the cognitive impairment associated with Alzheimer's disease?
Ben Hassine_2021_Molecules_26_ Untargeted Phytochemical Profile, Antioxidant Capacity and Enzyme Inhibitory Activity of Cultivated and Wild Lupin Seeds from Tunisia
Bezerra_2021_Bioorg.Med.Chem_44_116299 Larvicidal activity and in silico studies of cinnamic acid derivatives against Aedes aegypti (Diptera: Culicidae)
Bone_2021_Bull.Entomol.Res__1 Characterization of the pyrethroid resistance mechanisms in a Blattella germanica (Dictyoptera: Blattellidae) strain from Buenos Aires (Argentina)
Bononi_2021_Eur.J.Med.Chem_223_113679 Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold
Boulajfene_2021_Life.(Basel)_11_ Integrated Biomarker Response for Environmental Assessment Using the Gastropod Phorcus turbinatus along the Northern and the Northeastern Coasts of Tunisia
Bures_2021_Pharmaceuticals.(Basel)_14_ Dextran Sodium Sulphate-Induced Gastrointestinal Injury Further Aggravates the Impact of Galantamine on the Gastric Myoelectric Activity in Experimental Pigs
Cabodevilla_2021_J.Clin.Invest_131_ Eruptive xanthoma model reveals endothelial cells internalize and metabolize chylomicrons, leading to extravascular triglyceride accumulation
Calahorro_2021_Toxicol.Rep_8_1240 Impact of drug solvents on C. elegans pharyngeal pumping
Castaneda_2021_Mar.Drugs_19_ Bridging Cyanobacteria to Neurodegenerative Diseases: A New Potential Source of Bioactive Compounds against Alzheimer's Disease
Chang_2021_Molecules_26_ Regiospecific Positioning of Palmitic Acid in Triacylglycerol Structure of Enzymatically Modified Lipids Affects Physicochemical and In Vitro Digestion Properties
Charlie-Silva_2021_J.Hazard.Mater_419_126463 Toxicological insights of Spike fragments SARS-CoV-2 by exposure environment: A threat to aquatic health?
Covey_2021_J.Neurosci__ Chronic augmentation of endocannabinoid levels persistently increases dopaminergic encoding of reward cost and motivation
de Araujo_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122826 Is zebrafish (Danio rerio) water tank model applicable for the assessment of glucocorticoids metabolism? The budesonide assessment
de Vries_2021_Plant.Biotechnol.J__ CRISPR-Cas9 Editing of CAFFEOYL SHIKIMATE ESTERASE 1 and 2 Shows Their Importance and Partial Redundancy in Lignification in Populus tremula x P. alba
Deuther-Conrad_2021_RSC.Med.Chem_12_1000 Studies on the affinity of 6-[(n-(cyclo)aminoalkyl)oxy]-4H-chromen-4-ones for sigma 1\/2 receptors
Diaconu_2021_J.Enzyme.Inhib.Med.Chem_36_68 Lipoprotein-associated phospholipase A2 (Lp-PLA2) - possible diagnostic and risk biomarker in chronic ischaemic heart disease
Dos Santos_2021_Int.J.Mol.Sci_22_ Selective Extraction of Piceatannol from Passiflora edulis by-Products: Application of HSPs Strategy and Inhibition of Neurodegenerative Enzymes
Ebadollahi_2021_Int.J.Environ.Res.Public.Health_18_ Acaricidal, Insecticidal, and Nematicidal Efficiency of Essential Oils Isolated from the Satureja Genus
Eroglu_2021_Noro.Psikiyatr.Ars_58_166 Atypical Neuroleptic Malignant Syndrome Induced by Low Dose Quetiapine in a Patient Treated with Donepezil
Filip_2021_Cell.Chem.Biol_28_202 Profiling of MicroRNA Targets Using Activity-Based Protein Profiling: Linking Enzyme Activity to MicroRNA-185 Function
Gao_2021_Mol.Plant.Microbe.Interact__MPMI08200235R The Role of Clt1-Regulated Xylan Metabolism in Melanin and Toxin Formation for the Pathogenicity of Curvularia lunata in Maize
Godyn_2021_Bioorg.Chem_114_105129 Cyanobiphenyls: Novel H(3) receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease
Goncalves_2021_Curr.Top.Med.Chem__ 2',6'-dihydroxy-4'-methoxy dihydrochalcone improves the cognitive impairment of Alzheimer's disease: a structure-activity relationship study
Graf_2021_J.Pharm.Sci__ Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation
Grevengoed_2021_J.Clin.Invest_131_ An abundant biliary metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides
Guo_2021_Biomater.Sci__ The facile formation of hierarchical mesoporous silica nanocarriers for tumor-selective multimodal theranostics
Hajlaoui_2021_Molecules_26_ Antimicrobial, Antioxidant, Anti-Acetylcholinesterase, Antidiabetic, and Pharmacokinetic Properties of Carum carvi L. and Coriandrum sativum L. Essential Oils Alone and in Combination
Han_2021_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1866_158988 Lipolysis and lipophagy play individual and interactive roles in regulating triacylglycerol and cholesterol homeostasis and mitochondrial form in zebrafish
Hilliou_2021_Insects_12_ Resistance in the Genus Spodoptera: Key Insect Detoxification Genes
Hou_2021_J.Med.Chem_64_123 Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development
Hu_2021_Am.J.Physiol.Heart.Circ.Physiol__ Soluble Epoxide Hydrolase Deletion Attenuated Nicotine-induced Arterial Stiffness via Limiting the Loss of SIRT1
Ismail_2021_Toxics_9_ Acute and Cumulative Effects of Repeated Exposure to Chlorpyrifos on the Liver and Kidney Function among Egyptian Adolescents
Kandasamy_2021_Int.J.Biol.Macromol__ In silico, theoretical biointerface analysis and in vitro kinetic analysis of amine compounds interaction with acetylcholinesterase and butyrylcholinesterase
Kandeda_2021_Evid.Based.Complement.Alternat.Med_2021_6610864 Ziziphus jujuba (Rhamnaceae) Alleviates Working Memory Impairment and Restores Neurochemical Alterations in the Prefrontal Cortex of D-Galactose-Treated Rats
Kang_2021_Pharmaceutics_13_2 Subcutaneously Injectable Hyaluronic Acid Hydrogel for Sustained Release of Donepezil with Reduced Initial Burst Release: Effect of Hybridization of Microstructured Lipid Carriers and Albumin
Kang_2021_Crit.Rev.Biotechnol__1 Liamocins biosynthesis, its regulation in Aureobasidium spp., and their bioactivities
Kim_2021_Pharmaceutics_13_ In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics
Kisova_2021_J.Biotechnol_335_55 Removal of overpainting from an historical painting of the XVIII Century: A yeast enzymatic approach
Kumar_2021_Mar.Pollut.Bull_170_112682 Metal determination and biochemical status of marine fishes facilitate the biomonitoring of marine pollution
Kundu_2021_Drug.Dev.Ind.Pharm__1 Potential alternatives to current cholinesterase inhibitors: An in silico drug repurposing approach
Lazewska_2021_Molecules_26_ Biphenylalkoxyamine Derivatives-Histamine H(3) Receptor Ligands with Butyrylcholinesterase Inhibitory Activity
Le Douce_2021_Front.Neurosci_15_651094 Subcommissural Organ-Spondin-Derived Peptide Restores Memory in a Mouse Model of Alzheimer's Disease
Li_2021_Int.Immunopharmacol_99_107920 IL-6 downregulates hepatic carboxylesterases via NF-kappaB activation in dextran sulfate sodium-induced colitis
Liu_2021_Handb.Clin.Neurol_179_175 The diagonal band of Broca in health and disease
Maliszewski_2021_Molecules_26_ 1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors
Mashimo_2021_Int.J.Mol.Sci_22_ Regulation of Immune Functions by Non-Neuronal Acetylcholine (ACh) via Muscarinic and Nicotinic ACh Receptors
Miceli_2021_Int.J.Mol.Sci_22_ A New Ultrasensitive Bioluminescence-Based Method for Assaying Monoacylglycerol Lipase
Miklosz_2021_Biomolecules_11_ Treadmill Running Changes Endothelial Lipase Expression: Insights from Gene and Protein Analysis in Various Striated Muscle Tissues and Serum
Morena_2021_Br.J.Pharmacol_178_983 Sex-dependent effects of endocannabinoid modulation of conditioned fear extinction in rats
Mushtaq_2021_Plants.(Basel)_10_ Biomolecular Evaluation of Lavandula stoechas L. for Nootropic Activity
Najjar_2021_Sci.Rep_11_13659 Optimizing the catalytic activities of methanol and thermotolerant Kocuria flava lipases for biodiesel production from cooking oil wastes
Nemade_2021_Aging.Dis_12_1021 An Update on Medical and Surgical Treatments of Parkinson's Disease
Okada_2021_Sci.Rep_11_13589 Different cholinergic cell groups in the basal forebrain regulate social interaction and social recognition memory
Olofinsan_2021_Andrologia__e14179 Ocimum tenuiflorum mitigates iron-induced testicular toxicity via modulation of redox imbalance, cholinergic and purinergic dysfunctions, and glucose metabolizing enzymes activities
Omi_2021_Cell.Biochem.Biophys__ Current Knowledge on the Biology of Lysophosphatidylserine as an Emerging Bioactive Lipid
Patel_2021_J.Biomol.Struct.Dyn__1 Carbazole-based semicarbazones and hydrazones as multifunctional anti-Alzheimer agents
Patel_2021_Saudi.J.Biol.Sci_28_3835 Phyto-constituents profiling of Luffa echinata and in vitro assessment of antioxidant, anti-diabetic, anticancer and anti-acetylcholine esterase activities
Piccialli_2021_Antioxidants.(Basel)_10_ The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAbeta(1-42) Oligomers in Primary Cortical Neurons
Poliserpi_2021_Chemosphere_284_131327 Tissue distribution and sublethal effects of imidacloprid in the South American grayish baywing (Agelaioides badius)
Proenca_2021_An.Acad.Bras.Cienc_93_e20191002 Purple grape juice consumption during the gestation reduces acetylcholinesterase activity and oxidative stress levels provoked by high-fat diet in hippocampus from adult female rats descendants
Qin_2021_J.Biotechnol_337_24 A mutant T1 lipase homology modeling, and its molecular docking and molecular dynamics simulation with fatty acids
Qu_2021_J.Cell.Physiol_236_4738 Androgen-dependent miR-125a-5p targets LYPLA1 and regulates global protein palmitoylation level in late-onset hypogonadism males
Ramirez_2021_Structure_29_635 Building and destroying synaptic bridges: How do Hevin\/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions?
Rodriguez_2021_Sci.Total.Environ_794_148754 Efficient production of polyhydroxybutyrate from slaughterhouse waste using a recombinant strain of Cupriavidus necator DSM 545
Sales_2021_Bioprocess.Biosyst.Eng__ Improved production of biocatalysts by Yarrowia lipolytica using natural sources of the biopolyesters cutin and suberin, and their application in hydrolysis of poly (ethylene terephthalate) (PET)
Shaha_2021_Curr.Microbiol__ Characterization of an Esterase Producing Bacterium from the Gut of Chironomus circumdatus (Bloodworms) and its Ability to Use Modified Phthalates
Shcherbitskaia_2021_Cells_10_ Prenatal Hyperhomocysteinemia Induces Glial Activation and Alters Neuroinflammatory Marker Expression in Infant Rat Hippocampus
Suarez_2021_Foods_10_ Neuroprotective Effect of Terpenoids Recovered from Olive Oil By-Products
Suciati_2021_J.Basic.Clin.Physiol.Pharmacol_32_313 Acetylcholinesterase inhibitory activity of extract and fractions from the root of Rauvolfia serpentina(L.) Bth.ex Kurz
Sufian_2021_J.Exp.Biol__ Early suppression of the endocannabinoid degrading enzymes FAAH and MAGL alters locomotor development in zebrafish
Sugasini_2021_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159002 Potential role of hepatic lipase in the accretion of docosahexaenoic acid (DHA) by the brain
Suo_2021_Colloids.Surf.B.Biointerfaces_206_111960 Enhancing bio-catalytic performance of lipase immobilized on ionic liquids modified magnetic polydopamine
Tel-Cayan_2021_Z.Naturforsch.C.J.Biosci__ Isolation and characterization of chemical constituents from Chaerophyllum bulbosum roots and their enzyme inhibitory and antioxidant effects
Tomovic_2021_J.Med.Chem__ Structure-Activity Relationship Analysis of Cocrystallized Gliptin-like Pyrrolidine, Trifluorophenyl, and Pyrimidine-2,4-Dione Dipeptidyl Peptidase-4 Inhibitors
Valencia-Quintana_2021_Int.J.Environ.Res.Public.Health_18_ Assessment of Cytogenetic Damage and Cholinesterases' Activity in Workers Occupationally Exposed to Pesticides in Zamora-Jacona, Michoacan, Mexico
Vergoossen_2021_Eur.J.Neurosci__ Timing and localization of myasthenia gravis-related gene expression
Villalta_2021_Plants.(Basel)_10_ Selective BuChE Inhibitory Activity, Chemical Composition, and Enantiomeric Content of the Essential Oil from Salvia leucantha Cav. Collected in Ecuador
Virk_2021_Environ.Sci.Pollut.Res.Int__ Ameliorative role of rolipram, PDE-4 inhibitor, against sodium arsenite-induced vascular dementia in rats
Wang_2021_J.Biotechnol_335_47 Conjugation of haloalkane dehalogenase DhaA with arabinogalactan to increase its stability
Wang_2021_J.Affect.Disord_292_565 Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve
Wang_2021_Biomolecules_11_ Micro-Aqueous Organic System: A Neglected Model in Computational Lipase Design?
Wang_2021_Int.J.Mol.Med_48_ Perspective on prenatal polychlorinated biphenyl exposure and the development of the progeny nervous system (Review)
Wang_2021_Biol.Pharm.Bull_44_999 4D-QSAR Molecular Modeling and Analysis of Flavonoid Derivatives as Acetylcholinesterase Inhibitors
Xin_2021_Int.J.Mol.Sci_22_ Catalytic Descriptors to Investigate Catalytic Power in the Reaction of Haloalkane Dehalogenase Enzyme with 1,2-Dichloroethane
Yang_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_262_120094 Ultrasensitive fluorescent probe for visual biosensing of esterase activity in living cells and its imaging application
Ye_2021_Trop.Anim.Health.Prod_53_366 Association analysis between FASN genotype and milk traits in Mediterranean buffalo and its expression among different buffalo tissues
Yokoi_2021_IBRO.Neurosci.Rep_11_1 Reversal of motor-skill transfer impairment by trihexyphenidyl and reduction of dorsolateral striatal cholinergic interneurons in Dyt1 GAG knock-in mice
Yoo_2021_Curr.Issues.Mol.Biol_43_405 Immature Persimmon Suppresses Amyloid Beta (Abeta) Mediated Cognitive Dysfunction via Tau Pathology in ICR Mice
Zafar_2021_Drug.Des.Devel.Ther_15_2679 Prospective Application of Two New Pyridine-Based Zinc (II) Amide Carboxylate in Management of Alzheimer's Disease: Synthesis, Characterization, Computational and in vitro Approaches
Zengin_2021_Plants.(Basel)_10_ Chemical Profiling and Biological Evaluation of Nepeta baytopii Extracts and Essential Oil: An Endemic Plant from Turkey
Zhao_2021_Chem.Biol.Interact__109571 Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics
Zhao_2021_Prog.Lipid.Res_83_101112 Phosphatidylserine-specific phospholipase A1: A friend or the devil in disguise
Arya_2021_Front.Plant.Sci_12_663165 The Plant Cuticle: An Ancient Guardian Barrier Set Against Long-Standing Rivals
Bi_2021_Pathol.Oncol.Res_27_580800 Cholinesterase is Associated With Prognosis and Response to Chemotherapy in Advanced Gastric Cancer
Bicca_2021_Environ.Sci.Pollut.Res.Int__ A subchronic low-dose exposure of a glyphosate-based herbicide induces depressive and anxious-like behavior in mice: quercetin therapeutic approach
Chertemps_2021_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_40_100867 Detoxification gene families in Phylloxera: Endogenous functions and roles in response to the environment
Ciftci_2021_Anticancer.Agents.Med.Chem__ Apoptotic Effect of Novel Benzimidazole Derivatives Bearing Pyridyl\/Pyrimidinyl Piperazine Moiety
Dai_2021_Methods.Mol.Biol_2356_199 Isolation and Functional Analysis of Effector Proteins of Magnaporthe oryzae
Di Consiglio_2021_Toxicol.Lett__ Human Variability in Carboxylesterases and carboxylesterase-related Uncertainty Factors for Chemical Risk Assessment
Erukainure_2021_Andrologia__e14175 Strawberry fruit (Fragaria x ananassa Romina) juice attenuates oxidative imbalance with concomitant modulation of metabolic indices linked to male infertility in testicular oxidative injury
Gao_2021_Bioorg.Chem_114_105149 Pharmacophore-based drug design of AChE and BChE dual inhibitors as potential anti-Alzheimer's disease agents
Grcic_2021_Environ.Pollut_288_117706 Sensitivity of midgut physiological parameters of Lymantria dispar L. larvae to benzo[a]pyrene in populations with different multigeneration contact to environmental pollutants
Hassan_2021_Pak.J.Pharm.Sci_34_47 Neuroprotective and antioxidant effect of Curcuma longa (Rhizome) methanolic extract on SH-SY5Y cells and Javanese medaka
Hatori_2021_Anticancer.Res_41_3583 Clinical Significance of PLA2G2A Expression in Gastric Cancer Patients who Receive Gastrectomy and Adjuvant S-1
Issotina_2021_J.Hypertens__ Pyridostigmine ameliorates preeclamptic features in pregnant rats by inhibiting tumour necrosis factor-alpha synthetsis and antagonizing tumour necrosis factor-alpha-related effects
Kaur_2021_Phytother.Res__ Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components
Keerthiraj_2021_Chem.Biodivers__ Nematicidal and molecular docking investigation of essential oils from Pogostemon cablin ecotypes against Meloidogyne incognita
Li_2021_Nat.Prod.Res__1 A new diterpenoid alkaloid from Delphinium gyalanum C. Marquand & Airy Shaw
Lopez_2021_J.Venom.Anim.Toxins.Incl.Trop.Dis_27_e20210009 Neuroactive venom compounds obtained from Phlogiellus bundokalbo as potential leads for neurodegenerative diseases: insights on their acetylcholinesterase and beta-secretase inhibitory activities in vitro
Majrashi_2021_J.Integr.Neurosci_20_321 beta-hydroxybutyric acid attenuates oxidative stress and improves markers of mitochondrial function in the HT-22 hippocampal cell line
Michels_2021_BMJ.Open_11_e042857 Butyrylcholinesterase as a perioperative complication marker in patients after transcatheter aortic valve implantation: a prospective observational study
Mizutani_2021_Mol.Cell.Neurosci_115_103653 Nectins and Nectin-like molecules in synapse formation and involvement in neurological diseases
Moghadam_2021_J.Mol.Graph.Model_107_107981 Computational evidence of new putative allosteric sites in the acetylcholinesterase receptor
Oh_2021_Sci.Rep_11_13953 Acetylcholinesterase and monoamine oxidase-B inhibitory activities by ellagic acid derivatives isolated from Castanopsis cuspidata var. sieboldii
Patel_2021_Inflammopharmacology__ Protective effect of andrographolide against STZ induced Alzheimer's disease in experimental rats: possible neuromodulation and Abeta((1-42)) analysis
Phadke_2021_Chem.Biol.Drug.Des__ Therapeutic potential of Ferulic acid and its derivatives in Alzheimer's disease- A systematic review
Rashedinia_2021_Biomed.Res.Int_2021_5577594 The Effect of a Traditional Preparation Containing Piper nigrum L. and Bunium persicum (Boiss.) B.Fedtsch. on Immobility Stress-Induced Memory Loss in Mice
Saleem_2021_Food.Chem.Toxicol__112404 Investigation into the biological properties, secondary metabolites composition, and toxicity of aerial and root parts of Capparis spinosa L.: An important medicinal food plant
Swaraz_2021_Biomed.Pharmacother_141_111859 Phytochemical profiling of Blumea laciniata (Roxb.) DC. and its phytopharmaceutical potential against diabetic, obesity, and Alzheimer's
Thapak_2021_Neuromolecular.Med__ Tranilast, a Transient Receptor Potential Vanilloid 2 Channel (TRPV2) Inhibitor Attenuates Amyloid beta-Induced Cognitive Impairment: Possible Mechanisms
Uckun_2021_Environ.Toxicol.Chem__ Evaluating Multiple Biochemical Markers in Xenopus laevis Tadpoles Exposed to the Pesticides Thiacloprid and Trifloxystrobin in Single and Mixed Forms
Uddin_2021_Evid.Based.Complement.Alternat.Med_2021_9995614 Anticholinesterase Activity of Eight Medicinal Plant Species: In Vitro and In Silico Studies in the Search for Therapeutic Agents against Alzheimer's Disease
Undiano_2021_Food.Chem.Toxicol__112408 Cu2+-dependent stereoselective hydrolysis of a chiral organophosphonothioate insecticide for domestic mammals' sera and its albumins
Wang_2021_Bioorg.Chem_114_105148 The chemical diversity, the attractant, anti-acetylcholinesterase, and antifungal activities of metabolites from biocontrol Trichoderma harzianum uncovered by OSMAC strategy
Weng_2021_Biomed.Pharmacother_141_111865 Syringaldehyde promoting intestinal motility with suppressing alpha-amylase hinders starch digestion in diabetic mice
Yang_2021_Nanotechnology__ A highly sensitive acetylcholinesterase electrochemical biosensor based on Au-Tb alloy nanospheres for determining organophosphate pesticides
Zhang_2021_Appl.Biochem.Biotechnol__ Identification and Characterization of a Novel Carboxylesterase Belonging to Family VIII with Promiscuous Acyltransferase Activity Toward Cyanidin-3-O-Glucoside from a Soil Metagenomic Library
Zhao_2021_Chemosphere_279_130542 Current insights into the microbial degradation for pyrethroids: strain safety, biochemical pathway, and genetic engineering
Zhao_2021_Food.Funct__ Neuroprotective effects of NDEELNK from sea cucumber ovum against scopolamine-induced PC12 cell damage through enhancing energy metabolism and upregulation of the PKA\/BDNF\/NGF signaling pathway
Baysal_2021_Molecules_26_ Identification of Phenolic Compounds by LC-MS\/MS and Evaluation of Bioactive Properties of Two Edible Halophytes: Limonium effusum and L. sinuatum
Boughattas_2021_Sci.Total.Environ_796_148959 Assessing the presence of microplastic particles in Tunisian agriculture soils and their potential toxicity effects using Eisenia andrei as bioindicator
Du_2021_Circ.Res__ A Neuroligin Isoform Translated by circNlgn Contributes to Cardiac Remodeling
Eom_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109142 Exposure to metals premixed with microplastics increases toxicity through bioconcentration and impairs antioxidant defense and cholinergic response in a marine mysid
Fang_2021_Sci.Total.Environ_796_149051 Enantioselective bioaccumulation and detoxification mechanisms of earthworms (Eisenia fetida) exposed to mandipropamid
Fu_2021_J.Pharm.Biomed.Anal_204_114266 An activatable chemiluminescence probe based on phenoxy-dioxetane scaffold for biothiol imaging in living systems
Harthern-Flint_2021_Front.Microbiol_12_670928 Experimental and Genomic Evaluation of the Oestrogen Degrading Bacterium Rhodococcus equi ATCC13557
Hernandez-Toledano_2021_Chem.Biol.Interact_346_109578 The cytoskeleton as a non-cholinergic target of organophosphate compounds
Iijima_2021_Pediatr.Neonatol__ Clinical and pathophysiologic relevance of autoantibodies in neonatal myasthenia gravis
Kakamad_2021_Int.J.Surg.Case.Rep_85_106149 Thymoma with osseous metaplasia\; a case report with a brief literature review
Khan_2021_Front.Pharmacol_12_678611 Development of Synergy-Based Combination for Learning and Memory Using in vitro, in vivo and TLC-MS-Bioautographic Studies
Kublicki_2021_Crit.Rev.Biotechnol__1 Wheat germ lipase: isolation, purification and applications
Lai_2021_Front.Neural.Circuits_15_676891 An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum
Li_2021_J.Cancer.Res.Ther_17_644 BCL6B hypermethylation predicts metastasis and poor prognosis in early-stage hepatocellular carcinoma after thermal ablation
Liu_2021_Gastroenterology.Res_14_157 Efficacy and Safety of Neostigmine and Decompressive Colonoscopy for Acute Colonic Pseudo-Obstruction: A Single-Center Analysis
Mzezewa_2021_J.Enzyme.Inhib.Med.Chem_36_1607 Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer's disease agents
Nakamura_2021_Clin.Case.Rep_9_e04424 Subcutaneous injection of organophosphate (Fenitrothion)-Management of preventing the appearance of toxic symptoms: A case report
Pashirova_2021_Chem.Biol.Interact__109577 Therapeutic nanoreactors for detoxification of xenobiotics: Concepts, challenges and biotechnological trends with special emphasis to organophosphate bioscavenging
Rastegari_2021_Mol.Divers__ Synthesis and evaluation of novel arylisoxazoles linked to tacrine moiety: in vitro and in vivo biological activities against Alzheimer's disease
Sajjadi_2021_Metab.Brain.Dis__ Amygdalus spinosissima root extract enhanced scopolamine-induced learning and memory impairment in mice
Seibel_2021_Curr.Alzheimer.Res__ Effects of Spices (Saffron, Rosemary, Cinnamon, Turmeric and Ginger) in Alzheimer's Disease
Seibert_2021_Alzheimers.Res.Ther_13_131 Efficacy and safety of pharmacotherapy for Alzheimer's disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials
Su_2021_BMC.Genomics_22_548 Genome-wide analysis and expression patterns of lipid phospholipid phospholipase gene family in Brassica napus L
Tagliaferri_2021_Cureus_13_e15581 A Case of COVID-19 Vaccine Causing a Myasthenia Gravis Crisis
Taktak_2021_J.Egypt.Public.Health.Assoc_96_21 Enhanced mosquitocidal efficacy of pyrethroid insecticides by nanometric emulsion preparation towards Culex pipiens larvae with biochemical and molecular docking studies
Uras_2021_Front.Neurosci_15_691222 In vivo Evaluation of a Newly Synthesized Acetylcholinesterase Inhibitor in a Transgenic Drosophila Model of Alzheimer's Disease
Zhou_2021_Biotechnol.Biofuels_14_156 Magnetic COFs as satisfied support for lipase immobilization and recovery to effectively achieve the production of biodiesel by great maintenance of enzyme activity
Abdelsalam_2021_J.Genet.Eng.Biotechnol_19_108 Metabolic profiling, in vitro propagation, and genetic assessment of the endangered rare plant Anarrhinum pubescens
Ali_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_263_120180 Structure and biomolecular recognition of nitro-BODIPY-andrographolide assembles for cancer treatment
Bowroju_2021_Bioorg.Med.Chem_45_116311 Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease
Cao_2021_J.Cancer.Res.Clin.Oncol__ Treatment efficacy and safety of regorafenib plus drug-eluting beads-transarterial chemoembolization versus regorafenib monotherapy in colorectal cancer liver metastasis patients who fail standard treatment regimens
Dubrana_2021_ACS.Chem.Neurosci__ An Antidote Screening System for Organophosphorus Poisoning Using Zebrafish Larvae
Evangelista_2021_J.Enzyme.Inhib.Med.Chem_36_1659 Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
Fitzgerald_2021_Int.J.Mol.Sci_22_ Norepinephrine May Oppose Other Neuromodulators to Impact Alzheimer's Disease
Gwozdzinski_2021_Cardiol.Res.Pract_2021_5569961 Alterations in the Plasma and Red Blood Cell Properties in Patients with Varicose Vein: A Pilot Study
Han_2021_Environ.Health.Perspect_129_77004 A Roadmap to the Structure-Related Metabolism Pathways of Per- and Polyfluoroalkyl Substances in the Early Life Stages of Zebrafish (Danio rerio)
Kassa_2021_Neurotox.Res__ Memantine and Its Combination with Acetylcholinesterase Inhibitors in Pharmacological Pretreatment of Soman Poisoning in Mice
Le_2021_Evid.Based.Complement.Alternat.Med_2021_6627648 Ocimum sanctum Linn. Extract Improves Cognitive Deficits in Olfactory Bulbectomized Mice via the Enhancement of Central Cholinergic Systems and VEGF Expression
Li_2021_J.Mol.Histol__ Prednisolone induces osteocytes apoptosis by promoting Notum expression and inhibiting PI3K\/AKT\/GSK3beta\/beta-catenin pathway
Mazej_2021_Molecules_26_ 4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B
Mihaylova_2021_Molecules_26_ GC-MS Metabolic Profile and alpha-Glucosidase-, alpha-Amylase-, Lipase-, and Acetylcholinesterase-Inhibitory Activities of Eight Peach Varieties
Mladenova_2021_Int.J.Mol.Sci_22_ A Galantamine-Curcumin Hybrid Decreases the Cytotoxicity of Amyloid-Beta Peptide on SH-SY5Y Cells
Mu_2021_Open.Life.Sci_16_703 Prognostic value of the neutrophil-to-lymphocyte ratio in acute organophosphorus pesticide poisoning
Murray_2021_Life.Sci__119845 Acute gene expression changes in the mouse hippocampus following a combined Gulf War toxicant exposure
Naldi_2021_Molecules_26_ Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity
Nemzer_2021_Molecules_26_ Quantification of Major Bioactive Constituents, Antioxidant Activity, and Enzyme Inhibitory Effects of Whole Coffee Cherries (Coffea arabica) and Their Extracts
Ongnok_2021_Neurotherapeutics__ Donepezil Protects Against Doxorubicin-Induced Chemobrain in Rats via Attenuation of Inflammation and Oxidative Stress Without Interfering With Doxorubicin Efficacy
Oyeka_2021_Cureus_13_e15641 Progressive Supranuclear Palsy: Improvement in Cognitive-Behavioral Disturbances and Motor-Function Disabilities Following Treatment With Antidepressants and Cholinesterase Inhibitors
Pann_2021_J.Asian.Nat.Prod.Res__1 Phenanthrenes from Dendrobium senile and their pancreatic lipase inhibitory activity
Penatzer_2021_Heliyon_7_e07552 Differential phosphoprotein signaling in the cortex in mouse models of Gulf War Illness using corticosterone and acetylcholinesterase inhibitors
Pierzynowski_2021_Biomed.Res.Int_2021_6647734 Difference in Performance of EPI Pigs Fed Either Lipase-Predigested or Creon-Supplemented Semielemental Diet
Prado_2021_Neurocrit.Care__1 Acetylcholinesterase Inhibitors in Myasthenic Crisis: A Systematic Review of Observational Studies
Samad_2021_Metab.Brain.Dis__ Reserpine-induced altered neuro-behavioral, biochemical and histopathological assessments prevent by enhanced antioxidant defence system of thymoquinone in mice
Santillan_2021_Pestic.Biochem.Physiol_177_104876 Multibiomarker responses and bioaccumulation of fipronil in Prochilodus lineatus exposed to spiked sediments: Oxidative stress and antioxidant defenses
Sari_2021_Drug.Dev.Res__ Potential of nafimidone derivatives against co-morbidities of epilepsy: In vitro, in vivo, and in silico investigations
Sharma_2021_Clin.Psychopharmacol.Neurosci_19_470 Efficacy of Ulinastatin and Sulforaphane Alone or in Combination in Rat Model of Streptozotocin Diabetes Induced Vascular Dementia
Spinelli_2021_Nat.Prod.Res__1 Natural multi-target modulators of pathological pathways in Alzheimer's disease isolated from the Rhinella arenarum skin
Swiatek_2021_Int.J.Mol.Sci_22_ LC-ESI-QTOF-MS\/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure
Teo_2021_J.Phys.Chem.B__ Modulation of Phospholipid Bilayer Properties by Simvastatin
Tsai_2021_Curr.Opin.Toxicol_26_49 Mechanisms of organophosphate neurotoxicity
van Mierlo_2021_Brain.Behav__ Rivastigmine for minor visual hallucinations in Parkinson's disease: A randomized controlled trial with 24 months follow-up
Vecchio_2021_J.Cent.Nerv.Syst.Dis_13_11795735211029113 The State of The Art on Acetylcholinesterase Inhibitors in the Treatment of Alzheimer's Disease
Vilela_2021_Front.Chem_9_708374 Co-Immobilized Capillary Enzyme Reactor Based on Beta-Secretase1 and Acetylcholinesterase: A Model for Dual-Ligand Screening
Volkhina_2021_Klin.Lab.Diagn_66_389 Prospects for the use of indicators of sialic acid metabolism in medicine (review of literature)
Wei_2021_Phytochemistry_190_112867 Euphorfinoids E-L: Diterpenoids from the roots of Euphorbia fischeriana with acetylcholinesterase inhibitory activity
Yang_2021_Cell.J_23_355 Neuroprotective Effects of Isoquercetin: An In Vitro and In Vivo Study
Yu_2021_Fish.Shellfish.Immunol__ Comparative transcriptome analysis of Chinese grass shrimp (Palaemonetes sinensis) hepatopancreas under ectoparasitic isopod (Tachaea chinensis) infection
Yu_2021_AMB.Express_11_108 Synthesis of ellagic acid glucoside using glucansucrase from Leuconostoc and characterization of this glucoside as a functional neuroprotective agent
Zhang_2021_Zhonghua.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_33_740 [Experimental study on liver injury induced by intraperitoneal hypertension under mechanical ventilation]
Berselli_2021_Chembiochem_22_2032 Novel Pet-Degrading Enzymes: Structure-Function from a Computational Perspective
Leitao_2021_Int.J.Mol.Sci_22_ Structural Insights into Carboxylic Polyester-Degrading Enzymes and Their Functional Depolymerizing Neighbors
Li_2021_Biomacromolecules_22_2256 Synthesis, Enzymatic Degradation, and Polymer-Miscibility Evaluation of Nonionic Antimicrobial Hyperbranched Polyesters with Indole or Isatin Functionalities
Maity_2021_Appl.Biochem.Biotechnol_193_2699 Emerging Roles of PETase and MHETase in the Biodegradation of Plastic Wastes
Agrawal_2021_Bioresour.Technol_339_125603 Economizing the lignocellulosic hydrolysis process using heterologously expressed auxiliary enzymes feruloyl esterase D (CE1) and beta-xylosidase (GH43) derived from thermophilic fungi Scytalidium thermophilum
Cansiz_2021_Drug.Chem.Toxicol__1 Morphine attenuates neurotoxic effects of MPTP in zebrafish embryos by regulating oxidant\/antioxidant balance and acetylcholinesterase activity
Carniel_2021_Biotechnol.Adv__107811 A comprehensive and critical review on key elements to implement enzymatic PET depolymerization for recycling purposes
Dhamodharan_2021_Mol.Divers__ Machine learning models for predicting the activity of AChE and BACE1 dual inhibitors for the treatment of Alzheimer's disease
Dolezal_2021_J.Biomol.Struct.Dyn__1 Accuracy and precision of binding free energy prediction for a tacrine related lead inhibitor of acetylcholinesterase with an arsenal of supercomputerized molecular modelling methods: a comparative study
Ducrot_2021_FASEB.J_35_e21791 Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals
Feng_2021_Mikrochim.Acta_188_280 SERS-ELISA determination of human carboxylesterase 1 using metal-organic framework doped with gold nanoparticles as SERS substrate
Francis_2021_Nat.Prod.Res__1 Clathriketal, a new tricyclic spiroketal compound from marine sponge Clathria prolifera attenuates serine exopeptidase dipeptidyl peptidase-IV
Ganeshpurkar_2021_Mol.Divers__ Improved machine learning scoring functions for identification of Electrophorus electricus's acetylcholinesterase inhibitors
Harada_2021_Appl.Microbiol.Biotechnol__ Carboxylesterases for the hydrolysis of acetoacetate esters and their applications in terpenoid production using Escherichia coli
Hemaida_2021_ACS.Omega_6_19202 Synthesis and Biological Evaluation of Thiazole-Based Derivatives as Potential Acetylcholinesterase Inhibitors
Ibrahim_2021_Neuropharmacol__108738 Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4\/NF-kB\/NLRP3 pathways
Islam_2021_BMC.Complement.Med.Ther_21_204 Evaluation of cholinesterase inhibitory and antioxidant activity of Wedelia chinensis and isolation of apigenin as an active compound
Jenkins_2021_Nurs.Crit.Care__ Looking after each other in a crisis-Lessons from Novichok and the parallels with Covid-19
Joao_2021_ChemMedChem__ Homarine alkyl esters derivatives as new promising acetylcholinesterase inhibitors
Khadrawy_2021_Eur.J.Pharmacol_908_174384 Antidepressant effects of curcumin-coated iron oxide nanoparticles in a rat model of depression
Kristensen_2021_Front.Cell.Dev.Biol_9_702508 GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity
Lamb_2021_Environ.Sci.Process.Impacts__ Towards a comprehensive understanding of malathion degradation: theoretical investigation of degradation pathways and related kinetics under alkaline conditions
Loganathan_2021_Neurotoxicol__ Astaxanthin-s-allyl cysteine diester against high glucose-induced neuronal toxicity in vitro and diabetes-associated cognitive decline in vivo: Effect on p53, oxidative stress and mitochondrial function
Lyczko_2021_Microb.Biotechnol__ The catalytic activity of mycelial fungi towards 7-oxo-DHEA - an endogenous derivative of steroidal hormone dehydroepiandrosterone
Mendonca-Gomes_2021_Environ.Pollut_289_117818 Shedding light on toxicity of SARS-CoV-2 peptides in aquatic biota: A study involving neotropical mosquito larvae (Diptera: Culicidae)
Negi_2021_Curr.Drug.Metab__ Medicinal Plants and Natural Products, More Effective and Safer Pharmacological Treatment for the Management of Obesity
Raghuvanshi_2021_Phytomedicine_91_153659 Identification of plant-based multitargeted leads for Alzheimer's disease: In-vitro and in-vivo validation of Woodfordia fruticosa (L.) Kurz
Reyhani_2021_J.Econ.Entomol__ Salicylic Acid Induced Resistance in Drought-Stressed Pistachio Seedlings Influences Physiological Performance of Agonoscena pistaciae (Hemiptera: Aphalaridae)
Santos_2021_Environ.Toxicol.Chem__ Sub-Chronic Exposure to Environmental Concentrations of Chlorpyrifos Affect Swimming Activity of Rainbow Trout Larvae
Sokolowski_2021_Sci.Total.Environ_794_148593 Cellular level response of the bivalve Limecola balthica to seawater acidification due to potential CO(2) leakage from a sub-seabed storage site in the southern Baltic Sea: TiTank experiment at representative hydrostatic pressure
Stalin_2021_Med.Chem__ Synthesis, molecular docking and mosquitocidal efficacy of lawsone and its derivatives against the dengue vector Aedes aegypti L. (Diptera: Culicidae)
Sun_2021_Environ.Res__111793 An integrated approach using chemical ecological risk assessment and multi-integrated biomarker indexes approach to assess pollution: A case study of Ruditapes philippinarum in four bays on the Shandong Peninsula in China
Sylvers-Davie_2021_Am.J.Physiol.Endocrinol.Metab__ Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8
Wang_2021_Clin.Chim.Acta__ Two novel Mutations of the LPL Gene in two Chinese family cases with Familial Chylomicronemia Syndrome
Wedn_2021_Biochem.Pharmacol_192_114703 Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: Therapeutic perspectives
Wiley_2021_Front.Physiol_12_699712 UPLC-MS\/MS Method for Analysis of Endocannabinoid and Related Lipid Metabolism in Mouse Mucosal Tissue
Xu_2021_3.Biotech_11_370 Bioinformatics analysis of PAE family in Populus trichocarpa and responsiveness to carbon and nitrogen treatment
Yamamoto_2021_Plant.Signal.Behav__1961062 Identification and molecular characterization of propionylcholinesterase, a novel pseudocholinesterase in rice
Yu_2021_Food.Chem_366_130650 Lipase-catalyzed two-step esterification for solvent-free production of mixed lauric acid esters with antibacterial and antioxidative activities
Zha_2021_Lett.Appl.Microbiol__ Two polyurethanases PueA and PueB are major extracellular lipases partly secreted by the mediation of their cognate ABC exporter AprDEF in Pseudomonas protegens Pf-5
Zhang_2021_World.J.Gastroenterol_27_3863 PPARGC1A rs8192678 G>A polymorphism affects the severity of hepatic histological features and nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease
Zheleva-Dimitrova_2021_Food.Chem.Toxicol__112446 Comprehensive chemical characterization and biological evaluation of two Acacia species: A. nilotica and A. ataxacantha
Al-Aqaba_2021_Br.J.Ophthalmol_105_285 In vivo confocal microscopy features and clinicohistological correlation of limbal nerve corpuscles
Benfante_2021_Aging.Clin.Exp.Res_33_823 Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders
Dodson_2021_Pediatr.Emerg.Care_37_e206 That's Not His Regular Formula: A Case of Organophosphate Poisoning in an Infant
Gul_2021_Acta.Neurol.Belg_121_529 Congenital myasthenic syndrome in Turkey: clinical and genetic features in the long-term follow-up of patients
Poirier_2021_Environ.Sci.Pollut.Res.Int_28_25081 Organophosphorus poisoning in animals and enzymatic antidotes
Rezaee_2021_Mol.Divers_25_45 Novel amide derivatives of 3-phenylglutaric acid as potent soluble epoxide hydrolase inhibitors
Riswanto_2021_Med.Chem_17_442 Anti-Cholinesterase Activity of Chalcone Derivatives: Synthesis, In Vitro Assay and Molecular Docking Study
Rawlings_2021_Biochem.(Lond)_43_73 Alan Barrett: an appreciation (21 August 1937-23 November 2020)
Annac_2021_J.Food.Biochem__e13881 The protective effects of pomegranate juice on lead acetate-induced neurotoxicity in the male rat: A histomorphometric and biochemical study
Anukanon_2021_ACS.Omega_6_19924 In Silico-Guided Rational Drug Design and Semi-synthesis of C(2)-Functionalized Huperzine A Derivatives as Acetylcholinesterase Inhibitors
Bargiel_2021_Medicina.(Kaunas)_57_ Recognized and Potentially New Biomarkers-Their Role in Diagnosis and Prognosis of Cardiovascular Disease
Chen_2021_Virulence_12_1563 A novel transcription factor UvCGBP1 regulates development and virulence of rice false smut fungus Ustilaginoidea virens
Choudhir_2021_J.Biomol.Struct.Dyn__1 A combinatorial approach to screen structurally diverse acetylcholinesterase inhibitory plant secondary metabolites targeting Alzheimer's disease
de Andrade Ramos_2021_RSC.Med.Chem_12_1154 Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties
De Marchi_2021_Environ.Sci.Pollut.Res.Int__ A multi-bioassay integrated approach to assess antifouling potential of extracts from the Mediterranean sponge Ircinia oros
Decio_2021_Ecotoxicol.Environ.Saf_223_112581 Enzymatic responses in the head and midgut of Africanized Apis mellifera contaminated with a sublethal concentration of thiamethoxam
Fais_2021_Plants.(Basel)_10_ Euphorbia characias: Phytochemistry and Biological Activities
Gautheron_2021_Elife_10_ EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence
Gavini_2021_Brain.Res.Bull__ Developmental nicotine exposure impairs memory and reduces acetylcholine levels in the hippocampus of mice
Gholivand_2021_Mol.Divers__ Synthesis, crystal structure, cholinesterase inhibitory activity, evaluation of insecticidal activities, and computational studies of new phosphonic acids
Gopi_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109161 Interactive effects of freshwater acidification and selenium pollution on biochemical changes and neurotoxicity in Oreochromis mossambicus
Gori_2021_Top.Curr.Chem.(Cham)_379_33 Organic-Molecule-Based Fluorescent Chemosensor for Nerve Agents and Organophosphorus Pesticides
Grigorev_2021_Mol.Inform__ Structural Fractal Analysis of the Active Site of Acetylcholinesterase in Complexes with Huperzine A, Galantamine, and Donepezil
Guan_2021_Bioorg.Med.Chem.Lett__128306 Design, synthesis, and cholinesterase inhibition assay of liquiritigenin derivatives as anti-Alzheimer's activity
Issac_2021_Life.Sci__119864 Oxidative stress induced antioxidant and neurotoxicity demonstrated in vivo zebrafish embryo or larval model and their normalization due to morin showing therapeutic implications
Krzyzowski_2021_Molecules_26_ Intergenerational Transmission of Resistance of Callosobruchus maculatus to Essential Oil Treatment
Li_2021_Molecules_26_ Phytochemical Composition, Antioxidant Activity, and Enzyme Inhibitory Activities (alpha-Glucosidase, Xanthine Oxidase, and Acetylcholinesterase) of Musella lasiocarpa
Lubbers_2021_Microb.Cell.Fact_20_151 Vanillic acid and methoxyhydroquinone production from guaiacyl units and related aromatic compounds using Aspergillus niger cell factories
Ma_2021_Mikrochim.Acta_188_294 Ratiometric sensing of butyrylcholinesterase activity based on the MnO(2) nanosheet-modulated fluorescence of sulfur quantum dots and o-phenylenediamine
Matsushita_2021_Chem.Res.Toxicol__ Metabolism-Coupled Cell-Independent Acetylcholinesterase Activity Assay for Evaluation of the Effects of Chlorination on Diazinon Toxicity
Nakkam_2021_Br.J.Clin.Pharmacol__ Genetic variants associated with severe cutaneous adverse reactions induced by carbamazepine
Nawaz_2021_J.Med.Entomol__ Current Status of Pyrethroids Resistance in Aedes aegypti (Culicidae: Diptera) in Lahore District, Pakistan: A Novel Mechanistic Insight
Ortmann_2021_ALTEX__ Photomotor response data analysis approach to assess chemical neurotoxicity with the zebrafish embryo
Oyibo_2021_J.Basic.Clin.Physiol.Pharmacol__ Carcinogen sodium arsenite disrupts antioxidant and redox homeostasis in Drosophila melanogaster
Ozten_2021_Bioorg.Chem_115_105225 Synthesis, molecular docking and molecular dynamics studies of novel tacrine-carbamate derivatives as potent cholinesterase inhibitors
Peran_2021_Psychopharmacology.(Berl)__ Functional connectivity and cognitive changes after donepezil treatment in healthy participants
Qi_2021_Cell.Rep_36_109469 Nucleus basalis stimulation enhances working memory by stabilizing stimulus representations in primate prefrontal cortical activity
Quezada_2021_Molecules_26_ Curcumin-Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders
Rahman_2021_Molecules_26_ Thiourea Derivatives, Simple in Structure but Efficient Enzyme Inhibitors and Mercury Sensors
Richbart_2021_Adv.Cancer.Res_152_1 Acetylcholinesterase and human cancers
Sajjad_2021_Saudi.J.Biol.Sci_28_4384 Chemical characterization and evaluation of the neuroprotective potential of Indigofera sessiliflora through in-silico studies and behavioral tests in scopolamine-induced memory compromised rats
Saputra_2021_Int.J.Mol.Sci_22_ Co-Treatment of Copper Oxide Nanoparticle and Carbofuran Enhances Cardiotoxicity in Zebrafish Embryos
Shan_2021_Enzyme.Microb.Technol_149_109832 Conjugation with inulin improves the environmental stability of haloalkane dehalogenase DhaA
Singh_2021_RSC.Med.Chem_12_1142 Human carboxylesterases and fluorescent probes to image their activity in live cells
Stading_2021_Semin.Cancer.Biol__ Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer
Tian_2021_J.Neurosci__ Autism Spectrum Disorder\/Intellectual Disability-associated mutations in Trio disrupt Neuroligin 1-mediated synaptogenesis
Toldi_2021_Pancreatology__ Missense PNLIP mutations impeding pancreatic lipase secretion cause protein misfolding and endoplasmic reticulum stress
Tribuiani_2021_Curr.Mol.Med__ Effects Of Doxycycline On Mice Neuromuscular Junction, In Situ
Varma_2021_Biotechnol.J__e2100133 Immobilization of transgenic plant cells towards bioprinting for production of a recombinant biodefense agent
Wang_2021_Molecules_26_ An Evolving Technology That Integrates Classical Methods with Continuous Technological Developments: Thin-Layer Chromatography Bioautography
Wang_2021_Theranostics_11_8535 Neuronal-driven glioma growth requires Galphai1 and Galphai3
Wu_2021_J.Fungi.(Basel)_7_ Synergistic Interaction between the Entomopathogenic Fungus Akanthomyces attenuatus (Zare & Gams) and the Botanical Insecticide Matrine against Megalurothrips usitatus (Bagrall)
Xiao_2021_Biomed.Res.Int_2021_5574207 Celastrol Attenuates Learning and Memory Deficits in an Alzheimer's Disease Rat Model
Yang_2021_Nat.Prod.Res__1 Stephtetrandrine A-D, bisbenzylisoquinoline alkaloids from Stephania tetrandra
Zhan_2021_Mol.Med.Rep_24_ Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma
Zhao_2021_J.Chromatogr.A_1653_462443 Development and characterization of a selective chromatographic approach to the rapid discovery of ligands binding to muscarinic-3 acetylcholine receptor
Adebayo_2021_Drug.Metab.Pers.Ther__ Cnidoscolus aconitifolius-supplemented diet enhanced neurocognition, endogenous antioxidants and cholinergic system and maintains hippocampal neuronal integrity in male Wistar rats
Ali_2021_Exp.Aging.Res__1 Behavioral, Biochemical and Histopathological effects of Standardised Pomegranate extract with Vinpocetine, Propolis or Cocoa in a rat model of Parkinson's disease
Almeida_2021_J.Inorg.Biochem_224_111560 Probing the acetylcholinesterase inhibitory activity of a novel Ru(II) polypyridyl complex and the supramolecular interaction by (STD)-NMR
Al-Serri_2021_Saudi.J.Biol.Sci_28_4717 Association between the lipoprotein lipase rs1534649 gene polymorphism in intron one with Body Mass Index and High Density Lipoprotein-Cholesterol
Bahloul_2021_Acute.Crit.Care__ Clinical characteristics and outcomes of critically ill COVID-19 patients in Sfax, Tunisia
Barbeche_2021_Curr.Top.Med.Chem__ Chemical composition, acetylcholine esterase and Anti-bacterial activities of essential oils of Elaeosilenum thapsioides (Desf.) Maire from Algeria
Bi_2021_Turk.J.Chem_45_805 Novel Mannich bases with strong carbonic anhydrases and acetylcholinesterase inhibition effects: 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2(3H)-benzoxazolones
Brito_2021_Genet.Mol.Biol_44_e20200367 Expression of methyl farnesoate epoxidase (mfe) and juvenile hormone esterase (jhe) genes and their relation to social organization in the stingless bee Melipona interrupta (Hymenoptera: Apidae)
Bruszt_2021_Psychopharmacology.(Berl)__ Potentiation of cognitive enhancer effects of Alzheimer's disease medication memantine by alpha7 nicotinic acetylcholine receptor agonist PHA-543613 in the Morris water maze task
Brzezinski-Sinai_2021_Sci.Rep_11_16687 Cholinesterase activity in serum during general anesthesia in patients with or without vascular disease
Byrne_2021_Green.Chem_23_5043 Enzyme-catalyzed synthesis of malonate polyesters and their use as metal chelating materials
Chagas_2021_Chemosphere_277_130279 Multiple endpoints of polylactic acid biomicroplastic toxicity in adult zebrafish (Danio rerio)
Chatterjee_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_250_109164 lambda cyhalothrin induced toxicity and potential attenuation of hematological, biochemical, enzymological and stress biomarkers in Cyprinus carpio L. at environmentally relevant concentrations: A multiple biomarker approach
Chen_2021_Chemosphere_286_131866 Tralopyril affects locomotor activity of zebrafish (Danio rerio) by impairing tail muscle tissue, the nervous system, and energy metabolism
Cikcikoglu_2021_Int.J.Environ.Health.Res__1 The use of Gammarus pulex as a model organism for ecotoxicological assessment of ibuprofen and propranolol at environmental relevant concentrations
Cuello_2021_Proc.Natl.Acad.Sci.U.S.A_118_ Leslie Iversen, a friend of friends and an inspiring light in neuropharmacology
Demir_2021_Turk.J.Biol_45_275 Polyhydroxyalkanoate accumulation in Streptomyces coelicolor affected by SCO7613 gene region
El Gizawy_2021_ACS.Omega_6_20492 Phenolic Profiling and Therapeutic Potential of Certain Isolated Compounds from Parkia roxburghii against AChE Activity as well as GABA(A) alpha5, GSK-3beta, and p38alpha MAP-Kinase Genes
El Khatabi_2021_Turk.J.Chem_45_647 Integrated 3D-QSAR, molecular docking, and molecular dynamics simulation studies on 1,2,3-triazole based derivatives for designing new acetylcholinesterase inhibitors
Foladi_2021_Radiol.Case.Rep_16_2857 CT features of Wolman disease (lysosomal acid lipase enzyme deficiency) - A case report
Fuchs_2021_Hepatology__ Hepatocyte-specific deletion of adipose triglyceride lipase (ATGL\/PNPLA2) ameliorates dietary induced steatohepatitis in mice
Gabriel_2021_Biotechnol.Biofuels_14_169 CAZymes from the thermophilic fungus Thermoascus aurantiacus are induced by C5 and C6 sugars
Gok_2021_Food.Chem_368_130775 Profiling the annual change of the neurobiological and antioxidant effects of five Origanum species in correlation with their phytochemical composition
Gong_2021_Bioengineered_12_5241 Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma
Hamidi_2021_Environ.Sci.Pollut.Res.Int__ Effect of petroleum wastewater treated with gravity separation and magnetite nanoparticles adsorption methods on the blood biochemical response of mrigal fish (Cirrhinus cirrhosus)
Hu_2021_Thorac.Cardiovasc.Surg__ Diagnostic Value of Cholinesterase Activity for Postoperative Delirium
Huang_2021_J.Hazard.Mater_421_126830 Micro\/nano-plastics cause neurobehavioral toxicity in discus fish (Symphysodon aequifasciatus): Insight from brain-gut-microbiota axis
Ibrahim_2021_Neurochem.Res__ Neuroprotective Potential of Berberine Against Doxorubicin-Induced Toxicity in Rat's Brain
Jamal_2021_Environ.Sci.Pollut.Res.Int__ Molecular docking and dynamics studies of cigarette smoke carcinogens interacting with acetylcholinesterase and butyrylcholinesterase enzymes of the central nervous system
Jiang_2021_Zhonghua.Yi.Xue.Za.Zhi_101_2448 [Diagnostic value of combined detection of different indicators for type 2 diabetes mellitus combined with atherosclerotic disease]
Jiao_2021_ACS.Sens__ 3D-Printed, Portable, Fluorescent-Sensing Platform for Smartphone-Capable Detection of Organophosphorus Residue Using Reaction-Based Aggregation Induced Emission Luminogens
Johanif_2021_Environ.Pollut_289_117900 Bioaccumulation potential of chlorpyrifos in resistant Hyalella azteca: Implications for evolutionary toxicology
Klussendorf_2021_Mol.Neurobiol__ The Golgi-Associated PDZ Domain Protein Gopc\/PIST Is Required for Synaptic Targeting of mGluR5
Kumari_2021_Biomedicines_9_ The Importance of Lipoprotein Lipase Regulation in Atherosclerosis
Lee_2021_ACS.Nano__ Imaging Strategy that Achieves Ultrahigh Contrast by Utilizing Differential Esterase Activity in Organs: Application in Early Detection of Pancreatic Cancer
Li_2021_Life.Sci_283_119866 Morphine increases myocardial triacylglycerol through regulating adipose triglyceride lipase S406 phosphorylation
Li_2021_Front.Chem_9_713104 A Multi-Catalytic Sensing for Hydrogen Peroxide, Glucose, and Organophosphorus Pesticides Based on Carbon Dots
Li_2021_Eur.J.Med.Chem_225_113765 Identification and structure-activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus
Li_2021_Medicine.(Baltimore)_100_e26662 Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials
Liang_2021_Biosens.Bioelectron_193_113553 A novel biosensor based on multienzyme microcapsules constructed from covalent-organic framework
Lozano_2021_Sci.Total.Environ_800_149515 Ivermectin: A multilevel approach to evaluate effects in Prochilodus lineatus (Valenciennes, 1836) (Characiformes, Prochilodontidae), an inland fishery species
Moreira_2021_Food.Chem_367_130728 Chemometric evaluation of enzymatic hydrolysis in the production of fish protein hydrolysates with acetylcholinesterase inhibitory activity
Morris_2021_J.Alzheimers.Dis__ The Association Between Use of Rivastigmine and Pneumonia: Systematic Analysis of FDA Adverse Event Reporting System
Nagel_2021_BMC.Genomics_22_589 Increased abundance of secreted hydrolytic enzymes and secondary metabolite gene clusters define the genomes of latent plant pathogens in the Botryosphaeriaceae
Nguyen_2021_J.Ethnopharmacol__114520 The additive memory and healthspan enhancement effects by the combined treatment of mature silkworm powders and Korean angelica extracts
Pachon-Angona_2021_Future.Med.Chem__ Synthesis of new Hantzsch adducts showing Ca(2+) channel blockade capacity, cholinesterase inhibition and antioxidant power
Peluso_2021_Sci.Total.Environ_800_149510 Comprehensive assessment of water quality through different approaches: Physicochemical and ecotoxicological parameters
Perez-Iglesias_2021_Arch.Environ.Contam.Toxicol__ Multiple Level Effects of Imazethapyr on Leptodactylus latinasus (Anura) Adult Frogs
Pulido_2021_Biotechnol.Rep.(Amst)_31_e00659 Ethanol as additive enhance the performance of immobilized lipase LipA from Pseudomonas aeruginosa on polypropylene support
Qu_2021_Clin.Lab_67_ Evaluation of Lipoprotein-Associated Phospholipase A2 as a Prognostic Biomarker in Chronic Kidney Disease
Ramos-Flores_2021_Toxicol.Sci__ Temephos decreases sperm quality and fertilization rate and is metabolized in rat reproductive tissues at low dose exposure
Ribeiro_2021_Acta.Trop__106089 Molluscicidal activity of monoterpenes and their effects on inhibition of acetylcholinesterase activity on Biomphalaria glabrata, an intermediate host of Schistosoma mansoni
Rocchetti_2021_Food.Chem_368_130782 The functional potential of nine Allium species related to their untargeted phytochemical characterization, antioxidant capacity and enzyme inhibitory ability
Schwarthoff_2021_Bioorg.Med.Chem_46_116355 Evaluation of gamma-carboline-phenothiazine conjugates as simultaneous NMDA receptor blockers and cholinesterase inhibitors
Shang_2021_Biomolecules_11_ Lipoprotein Lipase and Its Delivery of Fatty Acids to the Heart
Sharma_2021_Free.Radic.Res__1 Oxidative damage in the liver and brain of the rats exposed to frequency-dependent radiofrequency electromagnetic exposure: Biochemical and histopathological evidence
Sinan_2021_Chem.Biodivers__ Biological insights and NMR metabolic profiling of different extracts of Spermacoce verticillata (L.) G. Mey
Spitler_2021_Am.J.Physiol.Endocrinol.Metab__ Chronic high fat feeding and prolonged fasting in liver-specific ANGPTL4 knockout mice
Taha_2021_Int.J.Biol.Macromol__ Exploring indole-based-thiadiazole derivatives as potent acetylcholinesterase and butyrylcholinesterase enzyme inhibitors
Tobin_2021_BMC.Res.Notes_14_315 Lipoprotein lipase hydrolysis products induce pro-inflammatory cytokine expression in triple-negative breast cancer cells
Veerabagu_2021_Front.Plant.Sci_12_674031 Lipid Body Dynamics in Shoot Meristems: Production, Enlargement, and Putative Organellar Interactions and Plasmodesmal Targeting
Wenzel_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1180_122891 Mass spectrometry-based targeted proteomics method for the quantification of clinically relevant drug metabolizing enzymes in human specimens
Wu_2021_Medicine.(Baltimore)_100_e26654 Case Report\/Case Series: Rare case of anti-LGI1 limbic encephalitis with rapidly progressive dementia, psychiatric symptoms, and frequently seizures: A case report
Wu_2021_Bioorg.Med.Chem.Lett__128316 Design, synthesis and biological evaluation of naringenin carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease
Yuan_2021_Clin.Lab_67_ Clinical Evaluation and Test of a Modified Lp-PLA2 Kit in Diagnosing Atherosclerosis
Abdulrahim_2021_J.Cannabis.Res_3_38 Cannabis sativa and\/or melatonin do not alter brain lipid but alter oxidative mechanisms in female rats
Abu-Taweel_2021_J.Trace.Elem.Med.Biol_68_126842 Pomegranate juice moderates anxiety- and depression-like behaviors in AlCl(3)-treated male mice
Alvi_2021_Oxid.Med.Cell.Longev_2021_9966663 Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway
Awan_2021_Biochem.Genet__ Genetic Association of Butyrylcholinesterase with Major Depressive Disorder
Cao_2021_Fitoterapia__104970 Secondary metabolites of endophytic fungi isolated from Huperzia serrata
Dong_2021_Biomed.Chromatogr__e5229 Enantioselective determination of phenthoate enantiomers in plant-origin matrices using reversed-phase high performance liquid chromatography-tandem mass spectrometry
Duplaine_2021_Neurol.Sci__ Myasthenia Gravis Lambert-Eaton overlap syndrome induced by nivolumab in a metastatic melanoma patient
Glucklich_2021_Eur.J.Pharm.Sci__105980 Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions
Guo_2021_J.Trace.Elem.Med.Biol_68_126844 Protective effects of pretreatment with Fe(2+), Cu(2+), and Rb(+) on phoxim poisoning in silkworm, Bombyx mori
He_2021_Environ.Res_203_111902 The relationship between pesticide exposure during critical neurodevelopment and autism spectrum disorder: A narrative review
Ke_2021_Ecotoxicol.Environ.Saf_224_112666 Heterologous expression and exploration of the enzymatic properties of the carbaryl hydrolase CarH from a newly isolated carbaryl-degrading strain
Lazarova_2021_J.Alzheimers.Dis__2 New Galantamine Derivatives with Inhibitory Effect on Acetylcholinesterase Activity
Liu_2021_Eur.J.Pharm.Sci__105976 Novel chrysin derivatives as hidden multifunctional agents for anti-Alzheimer's disease: design, synthesis and in vitro evaluation
Liu_2021_J.Pharm.Sci__ Characterization of Polysorbate 80 by Liquid Chromatography-Mass Spectrometry to Understand Its Susceptibility to Degradation and Its Oxidative Degradation Pathway
Osman_2021_Toxicology__152904 Effect of N-acetylcysteine on attenuation of chlropyrifos and its methyl analogue toxicity in male rats
Oyovwi_2021_Biomed.Pharmacother_142_112022 Kolaviron abates busulfan-induced episodic memory deficit and testicular dysfunction in rats: The implications for neuroendopathobiological changes during chemotherapy
Qiao_2021_Ecotoxicol.Environ.Saf_224_112672 Chemical composition of essential oils from Thymus mongolicus, Cinnamomum verum, and Origanum vulgare and their acaricidal effects on Haemaphysalis longicornis (Acari: Ixodidae)
Ruvinda_2021_Bull.Environ.Contam.Toxicol__ Toxicity of Titanium Dioxide Nanoparticles to Tadpoles of Asian Common Toad (Duttaphrynus melanostictus) Following Short Term and Chronic Exposures
Sahoo_2021_J.Biomol.Struct.Dyn__1 Comprehensive sequence and structure analysis of algal lipid catabolic enzyme Triacylglycerol lipase: an in silico study to vitalize the development of optimum engineered strains with high lipid productivity
Samad_2021_Environ.Sci.Pollut.Res.Int__ D-galactose induced dysfunction in mice hippocampus and the possible antioxidant and neuromodulatory effects of selenium
Suner_2021_J.Fluoresc__ Versatile Fluorescent Carbon Dots from Citric Acid and Cysteine with Antimicrobial, Anti-biofilm, Antioxidant, and AChE Enzyme Inhibition Capabilities
Tofiq_2021_J.Alzheimers.Dis__ Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study
Wu_2021_J.Enzyme.Inhib.Med.Chem_36_1860 Structure-activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease
Zare_2021_Drug.Chem.Toxicol__1 Apoptosis is involved in paraoxon-induced histological changes in rat cerebellum
Zhu_2021_J.Biosci.Bioeng__ Combining fermentation to produce O-succinyl-l-homoserine and enzyme catalysis for the synthesis of l-methionine in one pot
Akaberi_2021_Phytochemistry_191_112923 Phytochemistry and pharmacology of alkaloids from Glaucium spp
Al-Hamed_2021_Alzheimers.Dement.(N.Y)_7_e12184 Acetylcholinesterase inhibitors and risk of bleeding and acute ischemic events in non-hypertensive Alzheimer's patients
Anglister_2021_J.Neurochem__ Preface: Cholinergic mechanisms: This is the Preface for the special issue Cholinergic Mechanisms
Aramjoo_2021_Environ.Sci.Pollut.Res.Int__ Modulatory effect of opioid administration on the activity of cholinesterase enzyme: a systematic review of mice\/rat models
Aresti-Sanz_2021_Pharmaceuticals.(Basel)_14_ Stability of Methylphenidate under Various pH Conditions in the Presence or Absence of Gut Microbiota
Bai_2021_Environ.Microbiol__ Ric8 acts as a regulator of G-protein signaling required for nematode-trapping lifecycle of Arthrobotrys oligospora
Bjedov_2021_Animals.(Basel)_11_ Application of Non-Destructive Methods: Biomarker Assays in Blood of White Stork (Ciconia ciconia) Nestlings
Borah_2021_CNS.Neurol.Disord.Drug.Targets__ Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report
Boutoub_2021_Foods_10_ Comparative Study of the Antioxidant and Enzyme Inhibitory Activities of Two Types of Moroccan Euphorbia Entire Honey and Their Phenolic Extracts
Cai_2021_Molecules_26_ Bioactive Polyketide and Diketopiperazine Derivatives from the Mangrove-Sediment-Derived Fungus Aspergillus sp. SCSIO41407
Celik_2021_J.Biomol.Struct.Dyn__1 New chalcone derivative, ethyl 2-(4-(3-(benzo[b]thiophen-2-yl)acryloyl)phenoxy)acetate: synthesis, characterization, DFT study, enzyme inhibition activities and docking study
Chen_2021_Biomedicines_9_ Hydrolysable Tannins Exhibit Acetylcholinesterase Inhibitory and Anti-Glycation Activities In Vitro and Learning and Memory Function Improvements in Scopolamine-Induced Amnesiac Mice
Choi_2021_Nutrients_13_ Allium hookeri Extracts Improve Scopolamine-Induced Cognitive Impairment via Activation of the Cholinergic System and Anti-Neuroinflammation in Mice
Costas-Ferreira_2021_Int.J.Mol.Sci_22_ Neurotoxic Effects of Neonicotinoids on Mammals: What Is There beyond the Activation of Nicotinic Acetylcholine Receptors?-A Systematic Review
De Anna_2021_Pestic.Biochem.Physiol_178_104920 The insecticide chlorpyrifos modifies the expression of genes involved in the PXR and AhR pathways in the rainbow trout, Oncorhynchus mykiss
de Sa_2021_Mar.Drugs_19_ Anthraquinones, Diphenyl Ethers, and Their Derivatives from the Culture of the Marine Sponge-Associated Fungus Neosartorya spinosa KUFA 1047
Erban_2021_J.Proteomics_249_104356 Label-free proteomic analysis reveals differentially expressed Wolbachia proteins in Tyrophagus putrescentiae: Mite allergens and markers reflecting population-related proteome differences
Fabbri_2021_Int.J.Mol.Sci_22_ Biocatalyzed Synthesis of Flavor Esters and Polyesters: A Design of Experiments (DoE) Approach
Fabritius_2021_J.Clin.Med_10_ Bi-Centric Independent Validation of Outcome Prediction after Radioembolization of Primary and Secondary Liver Cancer
Fernandez-Galleguillos_2021_Metabolites_11_ UHPLC-MS Chemical Fingerprinting and Antioxidant, Antiproliferative, and Enzyme Inhibition Potential of Gaultheria pumila Berries
Fuzita_2021_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110670 A proteomic approach to identify digestive enzymes, their exocytic and microapocrine secretory routes and their compartmentalization in the midgut of Spodoptera frugiperda
Hafez_2021_Mar.Drugs_19_ Marine-Derived Compounds with Anti-Alzheimer's Disease Activities
Han_2021_Mar.Drugs_19_ Mixture of Phlorotannin and Fucoidan from Ecklonia cava Prevents the Abeta-Induced Cognitive Decline with Mitochondrial and Cholinergic Activation
Jan_2021_Oxid.Med.Cell.Longev_2021_4786227 Plant-Based Synthesis of Zinc Oxide Nanoparticles (ZnO-NPs) Using Aqueous Leaf Extract of Aquilegia pubiflora: Their Antiproliferative Activity against HepG2 Cells Inducing Reactive Oxygen Species and Other In Vitro Properties
Jiang_2021_Antioxidants.(Basel)_10_ Identification and Antioxidant Abilities of Enzymatic-Transesterification (-)-Epigallocatechin-3-O-gallate Stearyl Derivatives in Non-Aqueous Systems
Kadokura_2021_J.Nutr.Sci_10_e62 Effect of fish paste products, fish balls 'tsumire', intake in Sprague-Dawley rats
Kanuri_2021_HeartRhythm.Case.Rep_7_522 Autoimmune dysautonomia secondary to chronic organophosphate exposure
Kobenan_2021_Chem.Biodivers__ Chemical composition and spectrum of insecticidal activity of the essential oils of Ocimumgratissimum L. and Cymbopogoncitratus Stapf on the main insects of the cotton entomofauna in Cte d'Ivoire
Korabecny_2021_Biomolecules_11_ Cholinesterase Research
Liu_2021_Front.Plant.Sci_12_720816 Insecticidal Terpenes From the Essential Oils of Artemisia nakaii and Their Inhibitory Effects on Acetylcholinesterase
Lizama_2021_Antioxidants.(Basel)_10_ Analysis of Carotenoids in Haloarchaea Species from Atacama Saline Lakes by High Resolution UHPLC-Q-Orbitrap-Mass Spectrometry: Antioxidant Potential and Biological Effect on Cell Viability
Lupi_2021_Insects_12_ Combined Effects of Pesticides and Electromagnetic-Fields on Honeybees: Multi-Stress Exposure
Miao_2021_J.Nat.Prod_84_2374 Pd-Catalyzed Direct Diversification of Natural Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of N-Aryl Huperzine A Analogues
Muema_2021_Pestic.Biochem.Physiol_178_104912 Neurotoxic Zanthoxylum chalybeum root constituents invoke mosquito larval growth retardation through ecdysteroidogenic CYP450s transcriptional perturbations
Nambunmee_2021_J.Health.Pollut_11_210908 Pesticide Spraying and Reduced Cholinesterase Activity among Hill Tribe Farmers in Thailand
Ogunyewo_2021_Biotechnol.Biofuels_14_171 Accessory enzymes of hypercellulolytic Penicillium funiculosum facilitate complete saccharification of sugarcane bagasse
Oyeniran_2021_J.Basic.Clin.Physiol.Pharmacol__ Host-parasite relationship modulates the effect of African mistletoe leaves on the cholinergic, monoaminergic and carbohydrate hydrolyzing enzymes in fruit fly
Pan_2021_Int.J.Environ.Res.Public.Health_18_ Factors Affecting Rapid Cognitive Decline in Patients with Alzheimer's Disease: A Longitudinal Follow-Up Study
Quan_2021_J.Nat.Prod__ Configurational Assignment of a Flexible Benzo[g]isochromene Stereodiad from Rubia philippinensis and Inhibition of Soluble Epoxide Hydrolase Activity
Reid_2021_Curr.Alzheimer.Res__ Interaction of Exogenous Butyrylcholinesterase with beta-Amyloid Plaques in 5XFAD\/Butyrylcholinesterase-Knockout Mouse Brain
Richter_2021_Metabolites_11_ In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists QMPSB and QMPCB (SGT-11) Including Isozyme Mapping and Esterase Activity
Roohigohar_2021_PeerJ_9_e11762 Gene selection for studying frugivore-plant interactions: a review and an example using Queensland fruit fly in tomato
Saha_2021_Thorac.Cardiovasc.Surg__ Diagnostic Value of Cholinesterase Activity for the Development of Postoperative Delirium after Cardiac Surgery
Suttisansanee_2021_Plants.(Basel)_10_ Phytochemicals and In Vitro Bioactivities of Aqueous Ethanolic Extracts from Common Vegetables in Thai Food
Suwanhom_2021_Molecules_26_ Synthesis, Biological Evaluation, and In Silico Studies of New Acetylcholinesterase Inhibitors Based on Quinoxaline Scaffold
Triaca_2021_Adv.Exp.Med.Biol_1331_145 NGF and the Amyloid Precursor Protein in Alzheimer's Disease: From Molecular Players to Neuronal Circuits
Weber_2021_Eur.J.Gastroenterol.Hepatol__ Novel predictors for liver transplantation or death in drug-induced acute liver failure
Yamaga_2021_Nutrients_13_ Acetylcholine and Royal Jelly Fatty Acid Combinations as Potential Dry Eye Treatment Components in Mice
Yoshioka_2021_J.Agric.Food.Chem__ Inhibitory Activities of Sulfur Compounds in Garlic Essential Oil against Alzheimer's Disease-Related Enzymes and Their Distribution in the Mouse Brain
Zhang_2021_Int.Immunopharmacol_99_108035 Astilbin ameliorates oxidative stress and apoptosis in D-galactose-induced senescence by regulating the PI3K\/Akt\/m-TOR signaling pathway in the brains of mice
Geula_2021_J.Neurochem__ Basal forebrain cholinergic system in the dementias: Vulnerability, resilience, and resistance
Guillory_2021_Plant.Mol.Biol__ Phytohormone biosynthesis and signaling pathways of mosses
Megighian_2021_J.Neurochem__ Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets
Mulcahy_2021_J.Neurochem__ Protein profiling in the habenula after chronic (-)-menthol exposure in mice
Sankorrakul_2021_J.Neurochem__ Is there a role for the p75 neurotrophin receptor in mediating degeneration during oxidative stress and after hypoxia?
Zaru_2021_FEBS.J__ The Enzyme Portal: an integrative tool for enzyme information and analysis
Akincioglu_2021_Comput.Biol.Chem_94_107565 Cholinesterases, carbonic anhydrase inhibitory properties and in silico studies of novel substituted benzylamines derived from dihydrochalcones
Amezian_2021_Insect.Biochem.Mol.Biol_138_103646 Comparative analysis of the detoxification gene inventory of four major Spodoptera pest species in response to xenobiotics
Bajad_2021_Future.Med.Chem__ A systematic review of carbohydrate-based bioactive molecules for Alzheimer's disease
Baranowska-Kortylewicz_2021_J.Pediatr.Hematol.Oncol__ Multifarious Functions of Butyrylcholinesterase in Neuroblastoma: Impact of BCHE Deletion on the Neuroblastoma Growth In Vitro and In Vivo
Beversdorf_2021_Cogn.Behav.Neurol_34_182 The Effect of Donepezil on Problem-solving Ability in Individuals With Amnestic Mild Cognitive Impairment: A Pilot Study
Cao_2021_Front.Endocrinol.(Lausanne)_12_731273 Roles and Mechanisms of Dipeptidyl Peptidase 4 Inhibitors in Vascular Aging
Carver_2021_Front.Neurosci_15_681144 Blockade of TRPC Channels Limits Cholinergic-Driven Hyperexcitability and Seizure Susceptibility After Traumatic Brain Injury
Fan_2021_J.Ethnopharmacol__114572 Acer truncatum Bunge: A comprehensive review on ethnobotany, phytochemistry and pharmacology
Fan_2021_Pest.Manag.Sci__ Effects of elevated CO(2) on activities of protective and detoxifying enzymes in Frankliniella occidentalis and Frankliniella intonsa under spinetoram stress1
Gulcan_2021_Curr.Top.Med.Chem_21_2752 Dual monoamine oxidase and cholinesterase Inhibitors with different heterocyclic scaffolds
Hamdan_2021_Appl.Microbiol.Biotechnol__ Thermostable lipases and their dynamics of improved enzymatic properties
Huang_2021_Mikrochim.Acta_188_318 Integrating target-responsive CD-CdTe QD-based ratiometric fluorescence hydrogel with smartphone for visual and on-site determination of dichlorvos
Ilesanmi_2021_J.Ethnopharmacol__114592 Neuroprotective flavonoids of the leaf of Antiaris africana Englea against cyanide toxicity
Jamali_2021_J.Smok.Cessat_2021_9975811 Galantamine as a Treatment Option for Nicotine Addiction
Kong_2021_Ecotoxicol.Environ.Saf_225_112710 Old pesticide, new use: Smart and safe enantiomer of isocarbophos in locust control
Kratky_2021_Bioorg.Chem_116_105301 Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study
Liu_2021_Parasit.Vectors_14_450 In vitro and in vivo efficacy of thiacloprid against Echinococcus multilocularis
Miskovic_2021_Chem.Biodivers__ Mushroom Species Stereum hirsutum as Natural Source of Phenolics and Fatty Acids as Antioxidants and Acetylcholinesterase Inhibitors
Mitra_2021_Front.Aging.Neurosci_13_714186 Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers
Mohammed_2021_Lasers.Med.Sci__ Antidepressant and antioxidant effects of transcranial irradiation with 830-nm low-power laser in an animal model of depression
Onder_2021_J.Proteome.Res__ Rabbit Antidiethoxyphosphotyrosine Antibody, Made by Single B Cell Cloning, Detects Chlorpyrifos Oxon-Modified Proteins in Cultured Cells and Immunopurifies Modified Peptides for Mass Spectrometry
Patel_2021_Bioresour.Technol__125673 Lipolytic Nocardiopsis for reduction of pollution load in textile industry effluent and SWISS model for structural study of lipase
Pisani_2021_Int.J.Geriatr.Psychiatry_36_1471 A meta-analysis of randomised controlled trials of physical activity in people with Alzheimer's disease and mild cognitive impairment with a comparison to donepezil
Qin_2021_J.Colloid.Interface.Sci_606_1229 Hydrogen-bonded lipase-hydrogel microspheres for esterification application
Quinn_2021_Eur.J.Neurol__ European Stroke Organisation (ESO) and European Academy Neurology (EAN) Joint Guidelines on Post Stroke Cognitive Impairment
Rao_2021_Sci.Rep_11_17474 Revealing the molecular interplay of curcumin as Culex pipiens Acetylcholine esterase 1 (AChE1) inhibitor
Remya_2021_Comput.Struct.Biotechnol.J_19_4517 Neuroprotective derivatives of tacrine that target NMDA receptor and acetyl cholinesterase - Design, synthesis and biological evaluation
Sadafi_2021_Mol.Divers__ Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheimer's disease: Quinolotacrine hybrids
Santilli_2021_Neurologist_26_175 MuSK Myasthenia Gravis Presenting with Bilateral Vocal Cord Abduction Paresis: A Case Report and Literature Review
Sim_2021_Front.Neurosci_15_708547 Role of DPP-4 and SGLT2 Inhibitors Connected to Alzheimer Disease in Type 2 Diabetes Mellitus
Singh_2021_Bioorg.Med.Chem_46_116385 Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease
Song_2021_Med.Hypotheses_155_110666 SARM1-mediated wallerian degeneration: A possible mechanism underlying organophosphorus-induced delayed neuropathy
Sun_2021_Food.Chem.Toxicol_156_112516 Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3beta signaling pathway
Takahashi_2021_Front.Oncol_11_714527 Fluorescence Imaging Using Enzyme-Activatable Probes for Real-Time Identification of Pancreatic Cancer
Thukham-Mee_2021_Oxid.Med.Cell.Longev_2021_5520059 The Positive Modulation Effect of a 6-Week Consumption of an Anthocyanin-Rich Mulberry Milk on Working Memory, Cholinergic, and Monoaminergic Functions in Healthy Working-Age Adults
Tian_2021_Enzyme.Microb.Technol_150_109870 Enhanced activity of Rhizomucor miehei lipase by directed saturation mutation of the propeptide
Tucker_2021_Front.Vet.Sci_8_685824 Targeting Soluble Epoxide Hydrolase and Cyclooxygenases Enhance Joint Pain Control, Stimulate Collagen Synthesis, and Protect Chondrocytes From Cytokine-Induced Apoptosis
Ullah_2021_Int.Immunopharmacol_100_108083 Attenuation of spatial memory in 5xFAD mice by targeting cholinesterases, oxidative stress and inflammatory signaling using 2-(hydroxyl-(2-nitrophenyl)methyl)cyclopentanone
Xue_2021_CNS.Neurosci.Ther__ Identification of a large homozygous SPG21 deletion in a Chinese patient with Mast syndrome
Yamashita_2021_Mol.Ther.Methods.Clin.Dev_22_263 Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research
Zhao_2021_Bioorg.Chem_116_105307 Bioactive phenylpropanoid derivatives from the fruits of Lycium ruthenicum Murr
Zhou_2021_J.Hazard.Mater_416_126142 Physiological and transcriptomic changes of zebrafish (Danio rerio) embryos-larvae in response to 2-MIB exposure
Abdou_2021_Environ.Sci.Pollut.Res.Int__ Neurotoxicity and neuroinflammatory effects of bisphenol A in male rats: the neuroprotective role of grape seed proanthocyanidins
Al-Zaban_2021_Molecules_26_ HPLC-Analysis, Biological Activities and Characterization of Action Mode of Saudi Marrubium vulgare against Foodborne Diseases Bacteria
Baldinotti_2021_Eur.J.Pharmacol__174499 Protective effects of octylseleno-xylofuranoside in a streptozotocin-induced mouse model of Alzheimer's disease
Bigley_2021_Biochemistry__ Substrate Analogues for the Enzyme-Catalyzed Detoxification of the Organophosphate Nerve Agents-Sarin, Soman, and Cyclosarin
Cahlikova_2021_Molecules_26_ Recent Progress on Biological Activity of Amaryllidaceae and Further Isoquinoline Alkaloids in Connection with Alzheimer's Disease
Calsbeek_2021_Neurotoxicol__ Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate
Carvalho_2021_J.Chem.Theory.Comput__ Molecular Mechanism of Methanol Inhibition in CALB-Catalyzed Alcoholysis: Analyzing Molecular Dynamics Simulations by a Markov State Model
De Zutter_2021_Cancers.(Basel)_13_ The Role of Post-Translational Modifications of Chemokines by CD26 in Cancer
Dos Santos_2021_Nat.Prod.Res__1 Acetylcholinesterase and butyrylcholinesterase inhibition by nectriapyrone and tryptophol isolated from endophytic fungus Phomopsis sp
Dutta_2021_Front.Plant.Sci_12_714730 Deciphering the Behavioral Response of Meloidogyne incognita and Fusarium oxysporum Toward Mustard Essential Oil
Garmyn_2021_J.Wildl.Dis__ Persecution of Birds of Prey in Flanders: A Retrospective Study 2011-19
Hollenbach_2021_Adv.Biochem.Eng.Biotechnol__ Parameters Influencing Lipase-Catalyzed Glycolipid Synthesis by (Trans-)Esterification Reaction
Hu_2021_Nat.Prod.Res__1 Indole diketopiperazine alkaloids and aromatic polyketides from the Antarctic fungus Penicillium sp. SCSIO 05705
Jiang_2021_Arch.Insect.Biochem.Physiol__e21842 A role of peptidoglycan recognition protein in mediating insecticide detoxification in Glyphodes pyloalis
Karami_2021_Front.Aging.Neurosci_13_704583 CSF and Plasma Cholinergic Markers in Patients With Cognitive Impairment
Kirilovsky_2021_J.Toxicol.Environ.Health.A__1 Effects of acute arsenic exposure in two different populations of Hyalella curvispina amphipods from North Patagonia Argentina
Kumar_2021_Biochem.Biophys.Res.Commun_577_52 Arbutin protects brain against middle cerebral artery occlusion-reperfusion (MCAo\/R) injury
Kwon_2021_Acute.Crit.Care__ Continuous renal replacement therapy increased plasma cholinesterase activity in a case of acute organophosphate poisoning
Lajmanovich_2021_Sci.Total.Environ_804_150177 Glyphosate and glufosinate ammonium, herbicides commonly used on genetically modified crops, and their interaction with microplastics: Ecotoxicity in anuran tadpoles
Lu_2021_Front.Pharmacol_12_706762 Gender Disparities in Anti-dementia Medication Use among Older Adults: Health Equity Considerations and Management of Alzheimer's Disease and Related Dementias
Ma_2021_Talanta_235_122798 Magnetic covalent organic framework immobilized gold nanoparticles with high-efficiency catalytic performance for chemiluminescent detection of pesticide triazophos
Magar_2021_Int.J.Mol.Sci_22_ Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE
Martinez-Galan_2021_Food.Res.Int_148_110602 Enzymatic synthesis of capric acid-rich structured lipids and their effects on mice with high-fat diet-induced obesity
Mo_2021_Environ.Pollut_291_118120 Adsorption mechanism of two pesticides on polyethylene and polypropylene microplastics: DFT calculations and particle size effects
Noh_2021_Front.Oncol_11_634219 A Diagnostic Method for Gastric Cancer Using Two-Photon Microscopy With Enzyme-Selective Fluorescent Probes: A Pilot Study
Noyes_2021_Neuron__ Memory suppressor genes: Modulating acquisition, consolidation, and forgetting
Purgatorio_2021_Molecules_26_ First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease
Radhakrishnan_2021_Chemosphere_287_132163 Target-receptive structural switching of ssDNA as selective and sensitive biosensor for subsequent detection of toxic Pb(2+) and organophosphorus pesticide
Ruangritchankul_2021_Ther.Clin.Risk.Manag_17_927 Adverse Drug Reactions of Acetylcholinesterase Inhibitors in Older People Living with Dementia: A Comprehensive Literature Review
Sato_2021_Medicine.(Baltimore)_100_e27212 The association between sarcopenia and endotoxin in patients with alcoholic cirrhosis
Shamsi_2021_SAR.QSAR.Environ.Res_32_745 A modified binary particle swarm optimization with a machine learning algorithm and molecular docking for QSAR modelling of cholinesterase inhibitors
Sharma_2021_Molecules_26_ Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32
Singh_2021_Curr.Rev.Clin.Exp.Pharmacol__ Investigating Neuroprotective Potential of Berberine, Levetiracetam and Their Combination in The Management of Alzheimer's Disease Utilizing Drug Repurposing Strategy
Su_2021_Biosens.Bioelectron_194_113598 Background-free sensing platform for on-site detection of carbamate pesticide through upconversion nanoparticles-based hydrogel suit
Szmicsekova_2021_Physiol.Res__ Aortic butyrylcholinesterase is reduced in spontaneously hypertensive rats
Tahar_2021_Nat.Prod.Res__1 Chemical composition, antioxidant and anticholinesterase activity of the essential oil of algerian cachrys sicula L
Takahashi_2021_J.Clin.Med_10_ Prepregnancy Assessment of Liver Function to Predict Perinatal and Postpregnancy Outcomes in Biliary Atresia Patients with Native Liver
Temiz_2021_Environ.Sci.Pollut.Res.Int__ In vivo neurotoxic effects of emamectin benzoate in male mice: evaluation with enzymatic and biomolecular multi-biomarkers
Tomou_2021_Nat.Prod.Res__1 Polar constituents, biological effects and nutritional value of Sideritis sipylea Boiss
Umar_2021_Braz.J.Biol_83_e248842 Assessment of Cholinesterase inhibition activity of birds inhabiting pesticide exposed croplands and protected area in hot semi-arid region of Pakistan
Walczak-Nowicka_2021_Int.J.Mol.Sci_22_ Acetylcholinesterase Inhibitors in the Treatment of Neurodegenerative Diseases and the Role of Acetylcholinesterase in their Pathogenesis
Wang_2021_BMJ_374_n1925 Use of antipsychotic drugs and cholinesterase inhibitors and risk of falls and fractures: self-controlled case series
Yanxian_2021_Toxicology__152934 Toxic effects of subacute exposure to acrylamide on motor endplates of the gastrocnemius in rats
Yoo_2021_Sci.Rep_11_17914 Cacao powder supplementation attenuates oxidative stress, cholinergic impairment, and apoptosis in D-galactose-induced aging rat brain
Zambrano_2021_Int.J.Mol.Sci_22_ Protective Role of a Donepezil-Huprine Hybrid against the beta-Amyloid (1-42) Effect on Human Erythrocytes
Zhao_2021_Talanta_235_122784 A near-infrared light triggered fluormetric biosensor for sensitive detection of acetylcholinesterase activity based on NaErF(4): 0.5 \% Ho(3+)@NaYF(4) upconversion nano-probe
Zueva_2021_Chem.Biol.Interact__109646 alpha-tocopherol, a slow-binding inhibitor of acetylcholinesterase
Abdulkadir_2021_J.Alzheimers.Dis__ Taurine and Camel Milk Modulate Neurobehavioral and Biochemical Changes in Aluminum Chloride-Induced Alzheimer's Disease in Rats
Adeowo_2021_Chem.Biodivers__ Tailored Modeling of Rivastigmine Derivatives as Dual Acetylcholinesterase and Butyrylcholinesterase Inhibitors for Alzheimer's Disease Treatment
Akbar_2021_J.Food.Biochem__e13936 Neuroprotective potential of berberine in modulating Alzheimer's disease via multiple signaling pathways
Bacha_2021_Int.J.Phytoremediation__1 Protective effect of the Spirulina platensis against toxicity induced by Diuron exposure in Mytilus galloprovincialis
Balasch_2021_Mar.Pollut.Bull_172_112918 Short-term exposure to polymethylmethacrylate nanoplastics alters muscle antioxidant response, development and growth in Sparus aurata
Batista_2021_Environ.Pollut_290_118088 Importance of exposure route in determining nanosilver impacts on a stream detrital processing chain
Bhatia_2021_Physiol.Behav_241_113592 Thromboxane A2 synthase inhibition ameliorates endothelial dysfunction, memory deficits, oxidative stress and neuroinflammation in rat model of streptozotocin diabetes induced dementia
Bisht_2021_Trop.Anim.Health.Prod_53_460 Comparative susceptibility of Rhipicephalus microplus collected from the northern state of India to coumaphos, malathion, deltamethrin, ivermectin, and fipronil
Borkowski_2021_Alzheimers.Res.Ther_13_149 Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease
Borsini_2021_Brain.Behav.Immun.Health_16_100325 The role of soluble epoxide hydrolase and its inhibitors in depression
Callizot_2021_Front.Pharmacol_12_681532 Huperzia serrata Extract 'NSP01' With Neuroprotective Effects-Potential Synergies of Huperzine A and Polyphenols
Charles_2021_Redox.Biol_46_102107 A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation
Chen_2021_J.Hazard.Mater_422_126929 Atomically dispersed Fe\/Bi dual active sites single-atom nanozymes for cascade catalysis and peroxymonosulfate activation to degrade dyes
Dash_2021_J.Ethnopharmacol_282_114637 The modulatory role of prime identified compounds in Geophila repens in mitigating scopolamine-induced neurotoxicity in experimental rats of Alzheimer's disease via attenuation of cholinesterase, beta-secretase, MAPt levels and inhibition of oxidative stress imparts inflammation
de Oliveira_2021_Nat.Prod.Res__1 Biotic stress caused by in vitro co-inoculation enhances the expression of acetylcholinesterase inhibitors by fungi
Ding_2021_J.Comp.Neurol__ Cellular resolution anatomical and molecular atlases for prenatal human brains
Edinoff_2021_Anesth.Pain.Med_11_e117146 Adjuvant Drugs for Peripheral Nerve Blocks: The Role of NMDA Antagonists, Neostigmine, Epinephrine, and Sodium Bicarbonate
Edmison_2021_Brain.Sci_11_ Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias
Efjestad_2021_PLoS.One_16_e0243804 Sex differences in psychotropic and analgesic drug use before and after initiating treatment with acetylcholinesterase inhibitors
El Mourabit_2021_Environ.Sci.Pollut.Res.Int__ Assessment of the marine ecotoxic state in the Moroccan coastal area Anza-Taghazout following the installation of two wastewater treatment plants: a multibiomarker study using Mytilus galloprovincialis
Filippi_2021_Heliyon_7_e07921 Validation of exposure indexes to pesticides through the analysis of exposure and effect biomarkers in ground pesticide applicators from Argentina
Gao_2021_Ann.Transl.Med_9_1339 A novel method of subxiphoid video-assisted thoracic surgery for thymectomy
Gatford_2021_Hum.Mol.Genet__ Neuroligin-3 and Neuroligin-4X form Nanoscopic clusters and regulate growth cone organization and size
Gayathri_2021_CNS.Neurol.Disord.Drug.Targets__ Phytotherapeutics Against Alzheimer's Disease: Mechanism, Molecular Targets and Challenges for Drug Development
Ghodke_2021_Environ.Microbiol__ Environmental role of aromatic carboxylesterases
Gozutok_2021_Brain.Sci_11_ Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS
Gunay_2021_Semin.Cell.Dev.Biol_112_92 Importance of lipids for upper motor neuron health and disease
Gunderson_2021_Toxicol.Sci__ Neuroligin-1 is a mediator of methylmercury neuromuscular toxicity
Hassanzadeh_2021_Res.Pharm.Sci_16_482 Design, synthesis, and bio-evaluation of new isoindoline-1,3-dione derivatives as possible inhibitors of acetylcholinesterase
Ip_2021_Eur.J.Med.Chem_226_113827 A tacrine-tetrahydroquinoline heterodimer potently inhibits acetylcholinesterase activity and enhances neurotransmission in mice
Khuanjing_2021_Pharmacol.Res__105882 Acetylcholinesterase inhibitor ameliorates doxorubicin-induced cardiotoxicity through reducing RIP1-mediated necroptosis
Kulminskaya_2021_J.Biol.Chem__101206 Optimized expression and purification of adipose triglyceride lipase improved hydrolysis and transacylation catalytic activities in vitro
Kumar_2021_Ticks.Tick.Borne.Dis_12_101818 Characterization of deltamethrin, cypermethrin, coumaphos and ivermectin resistance in populations of Rhipicephalus microplus in India and efficacy of an antitick natural formulation prepared from Ageratum conyzoides
Macht_2021_J.Neuroinflammation_18_212 Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure
Maezawa_2021_J.Vet.Med.Sci__ Acute myelomonocytic leukemia negative for alpha-naphthyl acetate esterase stain in a Holstein cow
Mendez-Alvarez_2021_Mol.Divers__ Ligand-based virtual screening, molecular docking, and molecular dynamics of eugenol analogs as potential acetylcholinesterase inhibitors with biological activity against Spodoptera frugiperda
Patil_2021_In.Silico.Pharmacol_9_51 Erythrina variegata L. bark: an untapped bioactive source harbouring therapeutic properties for the treatment of Alzheimer's disease
Qi_2021_Nat.Prod.Res__1 A glyoxylate-containing benzene derivative and butenolides from a marine algicolous fungus Aspergillus sp. SCSIO 41304
Qian_2021_Curr.Med.Chem__ Research Progress on Dipeptidyl Peptidase Family: Structure, Function and Xenobiotic Metabolism
Sumra_2021_Environ.Monit.Assess_193_665 Biochemical characterization of Aedes aegypti (Linnaeus) (Diptera: Culicidae) resistance to deltamethrin, fipronil, and imidacloprid
Sun_2021_Am.J.Transl.Res_13_9315 Early enteral nutrition combined with PSS-based nursing in the treatment of organophosphorus pesticide poisoning
Takemoto_2021_Biochem.Pharmacol__114766 m(6)A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2
Verma_2021_Curr.Mol.Pharmacol__ A clinical perspective of soluble epoxide hydrolase inhibitors in metabolic and related cardiovascular diseases
Viana_2021_Environ.Sci.Pollut.Res.Int__ Bioconcentration and toxicological impacts of fipronil and 2,4-D commercial formulations (single and in mixture) in the tropical fish, Danio rerio
Wang_2021_Proteins__ The protonation state of Glu202 in acetylcholinesterase
Wu_2021_BMC.Pediatr_21_414 Rare novel LPL mutations are associated with neonatal onset lipoprotein lipase (LPL) deficiency in two cases
Xu_2021_Case.Rep.Gastrointest.Med_2021_9948854 The Effect of the Platelet Administration for the Patients with Liver Dysfunction after Liver Resection: Preliminary Clinical Trial
Yamasaki_2021_Intern.Med__ Two Lambert-Eaton Myasthenic Syndrome Patients with Ameliorated Activities of Daily Living Due to Cholinesterase Inhibitors
Yang_2021_Exp.Ther.Med_22_1252 Evidence-based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease
Pramod_2021_Front.Plant.Sci_12_704960 Saccharification Potential of Transgenic Greenhouse- and Field-Grown Aspen Engineered for Reduced Xylan Acetylation
Aboubakr_2021_Pharmaceuticals.(Basel)_14_ Antioxidant and Anti-Inflammatory Potential of Thymoquinone and Lycopene Mitigate the Chlorpyrifos-Induced Toxic Neuropathy
Akkol_2021_Curr.Neuropharmacol__ Effects of Natural Products on Neuromuscular Junction
Amirahmadi_2021_Metab.Brain.Dis__ Folic acid attenuated learning and memory impairment via inhibition of oxidative damage and acetylcholinesterase activity in hypothyroid rats
Bachurin_2021_Molecules_26_ Conjugation of Aminoadamantane and gamma-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands
Beddiar_2021_Plants.(Basel)_10_ Chemical Composition, Anti-Quorum Sensing, Enzyme Inhibitory, and Antioxidant Properties of Phenolic Extracts of Clinopodium nepeta L. Kuntze
Cannon_2021_Photochem.Photobiol__ Caged Oxime Reactivators Designed for the Light Control of Acetylcholinesterase Reactivation
Chao_2021_ACS.Sens__ BioChemPen for a Rapid Analysis of Compounds Supported on Solid Surfaces
de la Rubia Orti_2021_Nutrients_13_ Possible Role of Butyrylcholinesterase in Fat Loss and Decreases in Inflammatory Levels in Patients with Multiple Sclerosis after Treatment with Epigallocatechin Gallate and Coconut Oil: A Pilot Study
Decalf_2021_Bioorg.Chem_116_105376 A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants
El Kharraf_2021_Molecules_26_ Simultaneous Hydrodistillation-Steam Distillation of Rosmarinus officinalis, Lavandula angustifolia and Citrus aurantium from Morocco, Major Terpenes: Impact on Biological Activities
El Khatabi_2021_J.Mol.Model_27_302 Identification of novel acetylcholinesterase inhibitors through 3D-QSAR, molecular docking, and molecular dynamics simulation targeting Alzheimer's disease
Fukushi_2021_Clin.Exp.Nephrol__ Butyrylcholinesterase level as an independent prognostic factor for overall survival in patients on maintenance hemodialysis: a single-center retrospective study
Fuller_2021_Environ.Pollut_291_118217 Enhanced trophic transfer of chlorpyrifos from resistant Hyalella azteca to inland silversides (Menidia beryllina) and effects on acetylcholinesterase activity and swimming performance at varying temperatures
Giese_2021_Bioconjug.Chem__ Linker Architectures as Steric Auxiliaries for Altering Enzyme-Mediated Payload Release from Bioconjugates
Gonzalez-Barrio_2021_Parasit.Vectors_14_488 Changes in serum biomarkers of inflammation in bovine besnoitiosis
Guo_2021_Sci.Rep_11_18744 Acute benzo[a]pyrene exposure induced oxidative stress, neurotoxicity and epigenetic change in blood clam Tegillarca granosa
Guo_2021_Open.Biol_11_210106 ANGPTL8 in metabolic homeostasis: more friend than foe?
Hirasawa_2021_J.Nat.Med__ Cliniatines A-C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase
Hsu_2021_Diabetes.Metab.Syndr.Obes_14_3997 Association of Metabolic Syndrome with Aerobic Exercise and LPL rs3779788 Polymorphism in Taiwan Biobank Individuals
Imangaliyeva_2021_Carbohydr.Polym_273_118601 The polyaminosaccharide-based buffers as a new type of zwitterionic buffering macromolecules for biochemical applications
Jain_2021_Food.Chem_371_131126 Emerging vistas on pesticides detection based on electrochemical biosensors - An update
Kamei_2021_Patient.Prefer.Adherence_15_2103 Effect of Psychoeducational Intervention on Donepezil Retention Rate and Analysis of Reasons for the Discontinuation in Patients with Alzheimer's Dementia: A Randomized Study
Kang_2021_Pharmaceutics_13_ Co-Spray Dried Nafamostat Mesylate with Lecithin and Mannitol as Respirable Microparticles for Targeted Pulmonary Delivery: Pharmacokinetics and Lung Distribution in Rats
Karcz_2021_Int.J.Mol.Sci_22_ Novel Coumarin-Thiadiazole Hybrids and Their Cu(II) and Zn(II) Complexes as Potential Antimicrobial Agents and Acetylcholinesterase Inhibitors
Kersten_2021_Curr.Opin.Lipidol__ ANGPTL3 as therapeutic target
Khaoula_2021_Mol.Biol.Rep_48_6999 First characterization of congenital myasthenic syndrome type 5 in North Africa
Koike_2021_Cell.Tissue.Res__ Distribution, fine structure, and three-dimensional innervation of lamellar corpuscles in rat plantar skin
Lazarova_2021_J.Alzheimers.Dis__ Effects of New Galantamine Derivatives in a Scopolamine Model of Dementia in Mice
Lee_2021_Nutrients_13_ DW2009 Elevates the Efficacy of Donepezil against Cognitive Impairment in Mice
Ma_2021_J.Agric.Food.Chem__ Design, Synthesis, and Study of the Insecticidal Activity of Novel Steroidal 1,3,4-Oxadiazoles
Maafi_2021_Bioorg.Med.Chem.Lett_51_128374 Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study
Manzoor_2021_Bioorg.Chem_116_105354 Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer's disease
Masi_2021_Biomolecules_11_ Isolation and Biological Characterization of Homoisoflavanoids and the Alkylamide N-p-Coumaroyltyramine from Crinum biflorum Rottb., an Amaryllidaceae Species Collected in Senegal
Messenger_2021_Insect.Biochem.Mol.Biol__103655 A whole transcriptomic approach provides novel insights into the molecular basis of organophosphate and pyrethroid resistance in Anopheles arabiensis from Ethiopia
Michalovicz_2021_Life.Sci__119962 The beta-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness
Nazario-Yepiz_2021_PLoS.One_16_e0255198 Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase
Peng_2021_Phys.Chem.Chem.Phys__ A distal regulatory strategy of enzymes: from local to global conformational dynamics
Petkova-Tuffy_2021_BMC.Biol_19_215 Neuroligin-1 mediates presynaptic maturation through brain-derived neurotrophic factor signaling
Sager_2021_An.Acad.Bras.Cienc_93_e20201938 Multibiomarker responses in Danio rerio after exposure to sediment spiked with triclosan
Salau_2021_Sci.Rep_11_18724 Vanillin modulates activities linked to dysmetabolism in psoas muscle of diabetic rats
Salbini_2021_Molecules_26_ Oxidative Stress and Multi-Organel Damage Induced by Two Novel Phytocannabinoids, CBDB and CBDP, in Breast Cancer Cells
Sever_2021_Arch.Pharm.(Weinheim)__e2100294 Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds
Shaikh_2021_Oxid.Med.Cell.Longev_2021_6347792 Natural Products in Therapeutic Management of Multineurodegenerative Disorders by Targeting Autophagy
Singh_2021_Neurotox.Res__ Quercetin Exhibits alpha7nAChR\/Nrf2\/HO-1-Mediated Neuroprotection Against STZ-Induced Mitochondrial Toxicity and Cognitive Impairments in Experimental Rodents
Stockhoff_2021_Hepatol.Commun__ Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS
Sturve_2021_Mar.Pollut.Bull_173_112964 Effects of pesticides and metals on penaeid shrimps in Maputo Bay, Mozambique - A field study
Takomthong_2021_Pharmaceuticals.(Basel)_14_ Multi-Target Actions of Acridones from Atalantia monophylla towards Alzheimer's Pathogenesis and Their Pharmacokinetic Properties
Tamfu_2021_Molecules_26_ Non-Alkaloid Cholinesterase Inhibitory Compounds from Natural Sources
Todaka_2021_Eur.J.Pharmacol__174528 Donepezil, an anti-Alzheimer's disease drug, promotes differentiation and regeneration in injured skeletal muscle through the elevation of the expression of myogenic regulatory factors
Trifan_2021_Plants.(Basel)_10_1825 Influence of the Post-Harvest Storage Time on the Multi-Biological Potential, Phenolic and Pyrrolizidine Alkaloid Content of Comfrey (Symphytum officinale L.) Roots Collected from Different European Regions
Trobec_2021_Biomedicines_9_ Fine Tuning of Cholinesterase and Glutathione-S-Transferase Activities by Organoruthenium(II) Complexes
Turecky_2021_Bratisl.Lek.Listy_122_689 Serum butyrylcholinesterase activities in patients with non-alcoholic fatty liver disease. Comparison with liver proteosynthetic function and liver fibrosis
Usman_2021_Int.J.Environ.Res.Public.Health_18_ Polystyrene Microplastics Exposure: An Insight into Multiple Organ Histological Alterations, Oxidative Stress and Neurotoxicity in Javanese Medaka Fish (Oryzias javanicus Bleeker, 1854)
van Haren_2021_Biomolecules_11_1357 Esterase-Sensitive Prodrugs of a Potent Bisubstrate Inhibitor of Nicotinamide N-Methyltransferase (NNMT) Display Cellular Activity
Vokuev_2021_Anal.Bioanal.Chem__ Untargeted and targeted analysis of sarin poisoning biomarkers in rat urine by liquid chromatography and tandem mass spectrometry
Wan_2021_ACS.Omega_6_23347 Pd-Catalyzed Direct Modification of an Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of alpha-Aryl Donepezil Analogues
Wessinger_2021_Int.J.Exerc.Sci_14_727 Effect of Huperzine A on Cognitive Function and Perception of Effort during Exercise: A Randomized Double-Blind Crossover Trial
Xiong_2021_Brain.Sci_11_ Understanding the Modulatory Effects of Cannabidiol on Alzheimer's Disease
Xu_2021_J.Agric.Food.Chem_69_11554 Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
Yi_2021_Front.Physiol_12_674023 Identification of Candidate Carboxylesterases Associated With Odorant Degradation in Holotrichia parallela Antennae Based on Transcriptome Analysis
Yoon_2021_Medicine.(Baltimore)_100_e27252 Cognitive decline according to amyloid uptake in patients with poststroke cognitive impairment
Zanfirescu_2021_Molecules_26_ Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases
Zhou_2021_Chem.Biol.Drug.Des_98_997 Synthesis and activities of acetylcholinesterase inhibitors
Ahmed_2021_Pak.J.Pharm.Sci_34_855 1,3-di-4-piperidylpropane derivatives as potential acetyl cholinesterase antagonists: Molecular docking, synthesis, and biological evaluation
Al Mughairbi_2021_Saudi.Pharm.J_29_1043 Neuroprotective effects of Bhilawanol and Anacardic acid during glutamate-induced neurotoxicity
Almadiy_2021_Environ.Sci.Pollut.Res.Int__ Bioactivity and safety evaluations of Cupressus sempervirens essential oil, its nanoemulsion and main terpenes against Culex quinquefasciatus Say
Bakare_2021_BMC.Mol.Cell.Biol_22_49 Evaluation of selected carotenoids of Lycopersicon esculentum variants as therapeutic targets for 'Alzheimer's disease: an in silico approach
Boy_2021_Chem.Biodivers__ Synthesis, spectroscopic analysis, and in vitro\/in silico biological studies of novel piperidine derivatives heterocyclic Schiff-Mannich base compounds
Chekmarev_2021_Cells_10_ The Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity
Chigurupati_2021_Saudi.J.Biol.Sci_28_5579 Pharmacological and pharmacognostical valuation of Canna indica leaves extract by quantifying safety profile and neuroprotective potential
Cuttler_2021_Open.Biol_11_210091 Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders
Fontes_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109198 Environmentally realistic concentrations of cocaine in seawater disturbed neuroendrocrine parameters and energy status in the marine mussel Perna perna
Gorzi_2021_Mol.Neurobiol__ Training Intensity, Not Duration, May Be Key to Upregulating Presynaptic Proteins of Calcium Dynamics and Calcium-Dependent Exocytosis in Fast- and Slow-Twitch Skeletal Muscles, in Addition to Maintaining Performance After Detraining
Gumus_2021_Arch.Pharm.(Weinheim)__e2100242 Discovery of sulfadrug-pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors
Guo_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_266_120412 Determination of methomyl in grain using deep eutectic solvent-based extraction combined with fluorescence-based enzyme inhibition assays
Han_2021_Acc.Chem.Res__ Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer's Disease
Hughes_2021_PLoS.One_16_e0258134 Pesticides use and health impacts on farmers in Thailand, Vietnam, and Lao PDR: Protocol for a survey of knowledge, behaviours and blood acetyl cholinesterase concentrations
Iddir_2021_Food.Funct_12_9043 Gastric lipase can significantly increase lipolysis and carotenoid bioaccessibility from plant food matrices in the harmonized INFOGEST static in vitro digestion model
Jayaraman_2021_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159064 Heparin binding triggers human VLDL remodeling by circulating lipoprotein lipase: Relevance to VLDL functionality in health and disease
Jeong_2021_Biosci.Biotechnol.Biochem__ Enzymatic transformation products of phloretin as potent anti-adipogenic compounds
Kandeil_2021_J.Toxicol_2021_4411316 Nanonaringenin and Vitamin E Ameliorate Some Behavioral, Biochemical, and Brain Tissue Alterations Induced by Nicotine in Rats
Khoma_2021_Environ.Sci.Pollut.Res.Int__ Environmental concentrations of Roundup in combination with chlorpromazine or heating causes biochemical disturbances in the bivalve mollusc Unio tumidus
Kim_2021_J.Clin.Neurol_17_563 Neostigmine for Treating Acute Colonic Pseudo-Obstruction in Neurocritically Ill Patients
Koloski_2021_Ticks.Tick.Borne.Dis_13_101827 Transcriptional profiling of Dermacentor variabilis (Acari: Ixodidae) provides insights into the role of the Haller's organ in spatial DEET recognition
Kumar_2021_Eur.J.Pharmacol_911_174529 Ameliorative effect of myrcene in mouse model of Alzheimer's disease
Li_2021_Evid.Based.Complement.Alternat.Med_2021_7357521 Enteral Nutrition Combined with Improved-Sijunzi Decoction Shows Positive Effect in Precachexia Cancer Patients: A Retrospective Analysis
Liu_2021_Sci.Total.Environ__150681 Avobenzone and nanoplastics affect the development of zebrafish nervous system and retinal system and inhibit their locomotor behavior
Mahnashi_2021_BMC.Complement.Med.Ther_21_248 Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches
Malik_2021_Mol.Divers__ ABCpred: a webserver for the discovery of acetyl- and butyryl-cholinesterase inhibitors
Mayo_2021_Biol.Psychiatry__ Targeting the Endocannabinoid System in the Treatment of Posttraumatic Stress Disorder: A Promising Case of Preclinical-Clinical Translation?
Muller_2021_Microb.Cell.Fact_20_191 Scaling production of GFP1-10 detector protein in E. coli for secretion screening by split GFP assay
Oshige_2021_Bioorg.Med.Chem.Lett__128391 Synthesis of 3-octadecanoxypropyl 6-deoxy-6-sulfo-alpha-D-glucopyranoside (ODSG) as a lipase-resistant SQAP derivative
Oyebode_2021_Drug.Chem.Toxicol__1 Methanol fraction of Ficus mucoso (welw) prevents iron-induced oxidative damage and alters mitochondrial dysfunction in Drosophila melanogaster
Pan_2021_Chemosphere__132434 Degradation and toxicity of the antidepressant fluoxetine in an aqueous system by UV irradiation
Quan_2021_Int.J.Biol.Sci_17_3288 The role of N-cadherin\/c-Jun\/NDRG1 axis in the progression of prostate cancer
Ran_2021_Ecotoxicol.Environ.Saf_226_112809 The enantioselective toxicity and oxidative stress of dinotefuran on zebrafish (Danio rerio)
Siddiqui_2021_Biomed.Pharmacother_144_112250 Mechanistic role of boswellic acids in Alzheimer's disease: Emphasis on anti-inflammatory properties
Siwaraman_2021_CNS.Neurol.Disord.Drug.Targets__ Acetylcholinesterase Enzyme Inhibitor Molecules with Therapeutic Potential for Alzheimer's Disease
Skedsmo_2021_Neuromuscul.Disord_31_56 Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D
Zhang_2021_Biotechnol.Prog__e3218 Efficient enzymatic synthesis of L-ascorbyl palmitate using CALB-embedded metal-organic framework
Zhao_2021_J.Orthop.Surg.Res_16_364 NDRG1 regulates osteosarcoma cells via mediating the mitochondrial function and CSCs differentiation
Zheng_2021_Brain.Res__147672 Wheat Embryo Globulin Nutrients Ameliorate D-galactose and Aluminum Chloride-Induced Cognitive Impairment in Rats
Schopfer_2021_PLoS.One_16_e0254450 Evaluation of mass spectrometry MS\/MS spectra for the presence of isopeptide crosslinked peptides
Ng_2021_Int.J.Mol.Sci_22_ A Novel Lipase from Lasiodiplodia theobromae Efficiently Hydrolyses C8-C10 Methyl Esters for the Preparation of Medium-Chain Triglycerides' Precursors
Ahsan_2021_J.Basic.Microbiol__ Enzyme-assisted bioremediation approach for synthetic dyes and polycyclic aromatic hydrocarbons degradation
Anjireddy_2021_Mini.Rev.Med.Chem__ A new mode of Thinfilm and Nanofiber for burst release of the drug for Alzheimer disease\; A complete scenario from dispersible polymer to formulation methodology
Belinskaia_2021_Int.J.Mol.Sci_22_2 Serum Albumin in Health and Disease: Esterase, Antioxidant, Transporting and Signaling Properties
Belinskaia_2021_Int.J.Mol.Sci_22_ Esterase Activity of Serum Albumin Studied by (1)H NMR Spectroscopy and Molecular Modelling
Brioschi_2021_Alzheimers.Res.Ther_13_172 Protocols for cognitive enhancement. A user manual for Brain Health Services-part 5 of 6
Cabrera-Brandt_2021_Bull.Entomol.Res__1 Changes in the genetic composition of Myzus persicae nicotianae populations in Chile and frequency of insecticide resistance mutations
Cf_2021_Bioengineered_12_1040 Bioprospecting of gut microflora for plastic biodegradation
De Simone_2021_Int.J.Mol.Sci_22_ Serum Albumin: A Multifaced Enzyme
Di Rocco_2021_Hum.Mol.Genet__ Caenorhabditis elegans provides an efficient drug screening platform for GNAO1-related disorders and highlights the potential role of caffeine in controlling dyskinesia
Djapovic_2021_Chemosphere_275_130005 Synthesis and characterization of polyethylene terephthalate (PET) precursors and potential degradation products: Toxicity study and application in discovery of novel PETases
Fan_2021_Chemosphere_288_132491 Mechanistic insights into primary biotransformation of diethyl phthalate in earthworm and significant SOD inhibitory effect of esterolytic products
Fronza_2021_Brain.Behav.Immun__ Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: the role of blood-brain barrier permeability, NF-kB signaling, and microglial activation
Gonzalez_2021_Curr.Res.Toxicol_2_341 Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats
Guan_2021_Int.J.Mol.Sci_22_ Epoxyeicosatrienoic Acids and Fibrosis: Recent Insights for the Novel Therapeutic Strategies
Guo_2021_Bioengineered_12_7600 Preparation of MED1(transcription mediator subunit) gene nanocarrier and its mechanism of action on liver cell regeneration in chronic acute liver failure
Han_2021_Toxicol.Res_37_443 No prominent toxicity of polyethylene microplastics observed in neonatal mice following intratracheal instillation to dams during gestational and neonatal period
Jasiecki_2021_Int.J.Mol.Sci_22_ Butyrylcholinesterase-Protein Interactions in Human Serum
Karunatillaka_2021_Proteins__ Novel putative polyethylene terephthalate (PET) plastic degrading enzymes from the environmental metagenome
Kim_2021_Int.J.Mol.Sci_22_ Donepezil Regulates LPS and Abeta-Stimulated Neuroinflammation through MAPK\/NLRP3 Inflammasome\/STAT3 Signaling
Lee_2021_Cell.Rep.Phys.Sci_2_ A self-degradable hydrogel sensor for a nerve agent tabun surrogate through a self-propagating cascade
Liu_2021_Anal.Chim.Acta_1184_339026 A BCNO QDs-MnO(2) nanosheets based fluorescence off-on-off and colorimetric sensor with smartphone detector for the detection of organophosphorus pesticides
Liu_2021_Chemosphere_288_132492 Reproductive stimulation and energy allocation variation of BDE-47 and its derivatives on Daphnia magna
Meng_2021_Environ.Pollut__118333 Multigenerational effects modify the tolerance of mosquito larvae to chlorpyrifos but not to a heat spike and do not change their synergism
Moog_2021_Methods.Enzymol_648_435 Engineering microalgae as a whole cell catalyst for PET degradation
Moyses_2021_3.Biotech_11_435 Fungal and enzymatic bio-depolymerization of waste post-consumer poly(ethylene terephthalate) (PET) bottles using Penicillium species
Osuntokun_2021_Epilepsy.Behav_124_108333 Proanthocyanidin from Vitis vinifera attenuates memory impairment due to convulsive status epilepticus
Patisaul_2021_Epilepsy.Behav_124_105001 Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers
Perez-Garcia_2021_Methods.Enzymol_648_137 Exploring the global metagenome for plastic-degrading enzymes
Pirillo_2021_FEBS.J_288_4730 Analytical methods for the investigation of enzyme-catalyzed degradation of polyethylene terephthalate
Qiao_2021_Phys.Chem.Chem.Phys__ Effects of water on the solvation and structure of lipase in deep eutectic solvents containing a protein destabilizer and stabilizer
Redondo-Lopez_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_251_109208 Transient exposure to sublethal concentrations of a pesticide mixture (chlorpyrifos-difenoconazole) caused different responses in fish species from different trophic levels of the same community
Saravanan_2021_J.Biomol.Struct.Dyn__1 Probing the intermolecular interactions, binding affinity, charge density distribution and dynamics of silibinin in dual targets AChE and BACE1: QTAIM and molecular dynamics perspective
Schnitzler_2021_Mar.Pollut.Bull_163_111950 Lensless digital holographic microscopy as an efficient method to monitor enzymatic plastic degradation
Shaikh_2021_Bioorg.Chem_116_105397 Synthesis, characterization, in vitro cholinesterase and hRBCs hemolysis assay and computational evaluation of novel 2,3,4,5-tetrahydrobenzothiazepine appended alpha-aminophosphonates
Skomal_2021_Environ.Res__112163 Concurrent urinary organophosphate metabolites and acetylcholinesterase activity in Ecuadorian adolescents
Tanaka-Kanegae_2021_PLoS.One_16_e0258420 A novel in vitro assay model developed to measure both extracellular and intracellular acetylcholine levels for screening cholinergic agents
Teixeira_2021_Neurochem.Res__ Protective Effects of Inosine on Memory Consolidation in a Rat Model of Scopolamine-Induced Cognitive Impairment: Involvement of Cholinergic Signaling, Redox Status, and Ion Pump Activities
Wei_2021_ACS.Appl.Mater.Interfaces__ A Lab-in-a-Syringe Device Integrated with a Smartphone Platform: Colorimetric and Fluorescent Dual-Mode Signals for On-Site Detection of Organophosphorus Pesticides
Weigert_2021_Protein.Eng.Des.Sel_34_ A versatile assay platform for enzymatic poly(ethylene-terephthalate) degradation
Wojdylo_2021_Sci.Rep_11_20253 Comparison of bioactive compounds and health promoting properties of fruits and leaves of apple, pear and quince
Wu_2021_Org.Lett__ Millmerranones A-F: A Meroterpene Cyclic Carbonate and Related Metabolites from the Australian Fungus Aspergillus sp. CMB-MRF324
Xu_2021_Food.Chem_372_131256 An efficient and robust continuous-flow bioreactor for the enzymatic preparation of phytosterol esters based on hollow lipase microarray
Yan_2021_Environ.Sci.Technol__ Comprehensive Interrogation on Acetylcholinesterase Inhibition by Ionic Liquids Using Machine Learning and Molecular Modeling
Yang_2021_Arch.Toxicol__ Thifluzamide exposure induced neuro-endocrine disrupting effects in zebrafish (Danio rerio)
Yin_2021_Anat.Rec.(Hoboken)__ Acupuncture therapy for Alzheimer's disease: The effectiveness and potential mechanisms
Young_2021_Ann.Geriatr.Med.Res_25_170 Cardiovascular Complications of Acetylcholinesterase Inhibitors in Patients with Alzheimer's Disease: A Narrative Review
Zhu_2021_Trials_22_688 Efficiency of donepezil in elderly patients undergoing orthopaedic surgery due to underlying post-operative cognitive dysfunction: study protocol for a multicentre randomised controlled trial
Zhu_2021_Biosens.Bioelectron_196_113691 3D origami paper-based ratiometric fluorescent microfluidic device for visual point-of-care detection of alkaline phosphatase and butyrylcholinesterase
Abbad_2021_PLoS.One_16_e0258750 Effect of identified non-synonymous mutations in DPP4 receptor binding residues among highly exposed human population in Morocco to MERS-CoV through computational approach
Arora_2021_Ecotoxicol.Environ.Saf_226_112790 Mixture toxicity assessment of selected insecticides to silver perch fingerling, Bidyanus bidyanus
Azadniya_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1184_122956 High-throughput enzyme inhibition screening of 44 Iranian medicinal plants via piezoelectric spraying of planar cholinesterase assays
Balazs_2021_Geroscience__ Cholinesterase inhibitors for the treatment of dementia: real-life data in Hungary
Bondzic_2021_Chem.Biol.Interact__109708 Cytotoxic activity and influence on acetylcholinesterase of series dinuclear platinum(II) complexes with aromatic nitrogen-containing heterocyclic bridging ligands: Insights in the mechanisms of action
Bortolami_2021_ACS.Chem.Neurosci__ New Pyrimidine and Pyridine Derivatives as Multitarget Cholinesterase Inhibitors: Design, Synthesis, and In Vitro and In Cellulo Evaluation
Brandts_2021_Mar.Pollut.Bull_173_113018 A baseline study on the impact of nanoplastics on the portals of entry of xenobiotics in fish
Cheng_2021_Anal.Methods__ Biomimetic self-assembly of lipase-zeolitic imidazolate frameworks with enhanced biosensing of protox inhibiting herbicides
de Farias_2021_J.Environ.Sci.Health.A.Tox.Hazard.Subst.Environ.Eng__1 Neuromotor activity inhibition in zebrafish early-life stages after exposure to environmental relevant concentrations of caffeine
de Oliveira_2021_Food.Funct_12_9820 Bioactivity screening of pinho (Araucaria Angustifolia (Bertol.) Kuntze) seed extracts: the inhibition of cholinesterases and alpha-amylases, and cytotoxic and anti-inflammatory activities
de Oliveira Ribeiro_2021_Environ.Sci.Pollut.Res.Int__ Comparative effects of oral exposure to 2, 4, 6-tribromophenol and decabromodiphenyl ether in Nile tilapia
Durand_2021_J.Exp.Biol__ Neuroligin 1 expression is linked to plasticity of behavioral and neuronal responses to sex pheromone in the male moth Agrotis ipsilon
Esang_2021_Cureus_13_e17591 Aducanumab as a Novel Treatment for Alzheimer's Disease: A Decade of Hope, Controversies, and the Future
Fersht_2021_J.Mol.Biol_433_167088 AlphaFold - A Personal Perspective on the Impact of Machine Learning
Geethu_2021_Protein.J_40_669 Improved 3-D Protein Structure Predictions using Deep ResNet Model
Ishola_2021_Brain.Res.Bull__ Prevention and reversal of ketamine-induced experimental psychosis in mice by the neuroactive flavonoid, hesperidin: the role of oxidative and cholinergic mechanisms
Javed_2021_ACS.Chem.Neurosci__ Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer's Disease
Jing_2021_Food.Chem_370_131360 Application of deep eutectic solvent-based extraction coupled with an S-CQD fluorescent sensor for the determination of pirimicarb in cereals
Jumper_2021_Proteins__ Applying and improving AlphaFold at CASP14
Jumper_2021_Nature_596_583 Highly accurate protein structure prediction with AlphaFold
Kamecki_2021_Neuropharmacol_201_108837 Multitarget 2'-hydroxychalcones as potential drugs for the treatment of neurodegenerative disorders and their comorbidities
Kuentzel_2021_Int.J.Mol.Sci_22_ Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth
Li_2021_Mikrochim.Acta_188_385 A ratiometric fluorescence strategy based on inner filter effect for Cu(2+)-mediated detection of acetylcholinesterase
Lindgren_2021_J.Alzheimers.Dis__ Differences in Dementia Care Between Swedish-Born and Foreign-Born from Countries with Different Country Level Socioeconomic Position: A Nationwide Register-Based Study
Moyano_2021_Food.Chem.Toxicol__112614 Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF\/TrkA\/P75(NTR) signaling disruption
Mukhametgalieva_2021_Biochim.Biophys.Acta.Proteins.Proteom__140733 Steady-state kinetic analysis of human cholinesterases over wide concentration ranges of competing substrates
Mullard_2021_Nat.Rev.Drug.Discov_20_725 What does AlphaFold mean for drug discovery?
Ogidigo_2021_Toxicol.Mech.Methods__1 Neuroprotective effect of Bryophyllum pinnatum flavonoids against aluminium chloride-induced neurotoxicity in rats
Pengsook_2021_Pest.Manag.Sci__ Insecticidal and growth inhibitory effects of some thymol derivatives on the beet armyworm, Spodoptera exigua (Lepidoptera: Noctuidae) and their impact on detoxification enzymes
Ruff_2021_J.Mol.Biol_433_167208 AlphaFold and Implications for Intrinsically Disordered Proteins
Sawyer_2021_Toxicol.In.Vitro__105256 Acute and long-term effects of VX in rat brain cell aggregate culture
Schmitz_2021_Bioresour.Technol_343_126114 Lignocellulose degradation for the bioeconomy: The potential of enzyme synergies between xylanases, ferulic acid esterase and laccase for the production of arabinoxylo-oligosaccharides
Serpell_2021_J.Mol.Biol_433_167231 AlphaFold: A Special Issue and A Special Time for Protein Science
Shuchi_2021_Neurosci.Lett__136294 Neuromodulatory potential of Asparagus racemosus and its bioactive molecule Shatavarin IV by enhancing synaptic acetylcholine level and nAChR activity
Sirinupong_2021_Int.J.Food.Sci_2021_2213814 Hydrolase-Treated Royal Jelly Attenuates H(2)O(2)- and Glutamate-Induced SH-SY5Y Cell Damage and Promotes Cognitive Enhancement in a Rat Model of Vascular Dementia
Skolnick_2021_J.Chem.Inf.Model__ AlphaFold 2: Why It Works and Its Implications for Understanding the Relationships of Protein Sequence, Structure, and Function
Strodel_2021_J.Mol.Biol_433_167182 Energy Landscapes of Protein Aggregation and Conformation Switching in Intrinsically Disordered Proteins
Thornton_2021_Nat.Med_27_1666 AlphaFold heralds a data-driven revolution in biology and medicine
Tong_2021_Nat.Struct.Mol.Biol_28_771 Could AlphaFold revolutionize chemical therapeutics?
Tunyasuvunakool_2021_Nature_596_590 Highly accurate protein structure prediction for the human proteome
Watts_2021_Future.Cardiol__ Transcriptomic therapy for dyslipidemias utilizing nucleic acids targeted at ANGPTL3
Wei_2021_Appl.Microbiol.Biotechnol__ Metabolic engineering Yarrowia lipolytica for a dual biocatalytic system to produce fatty acid ethyl esters from renewable feedstock in situ and in one pot
Yoneten_2021_Cancer.Biomark__ Decreased serum levels of glycerol-3- phosphate dehydrogenase 1 and monoacylglycerol lipase act as diagnostic biomarkers for breast cancer
Zarafyants_2021_Sud.Med.Ekspert_64_32 [Forensic characteristics of the cardio-toxic effect of organophosphorus compounds]
Zhang_2021_Evid.Based.Complement.Alternat.Med_2021_6480381 Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease
Pleiss_2021_ChemCatChem_13_3909 Standardized Data, Scalable Documentation, Sustainable Storage - EnzymeML As A Basis For FAIR Data Management In Biocatalysis
Elias_2021_EMBO.Rep_22_e53256 Dan Salah Tawfik (1955-2021) A giant of protein evolution
Albendin_2021_Int.J.Environ.Res.Public.Health_18_ Pharmaceutical Products and Pesticides Toxicity Associated with Microplastics (Polyvinyl Chloride) in Artemia salina
Alexander_2021_Proteins__ Target highlights in CASP14: Analysis of models by structure providers
Atalar_2021_J.Food.Biochem__e13975 The effects of Daucus carota extract against PC3, PNT1a prostate cells, acetylcholinesterase, glutathione S-transferase, and alpha-glycosidase\; an in vitro-in silico study
Aydin_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_267_120501 A reaction-based system for the colorimetric detection of glyphosate in real samples
Baussanne_2021_Bioorg.Chem_116_105390 Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference
Cannon_2021_RSC.Med.Chem_12_1592 Dual acting oximes designed for therapeutic decontamination of reactive organophosphates via catalytic inactivation and acetylcholinesterase reactivation
Chen_2021_Front.Genet_12_740036 Comparative Analyses of Sperm DNA Methylomes Among Three Commercial Pig Breeds Reveal Vital Hypomethylated Regions Associated With Spermatogenesis and Embryonic Development
Cui_2021_Hypertension_78_1527 Inhibition of Soluble Epoxide Hydrolase Attenuates Bosutinib-Induced Blood Pressure Elevation
Dai_2021_Insects_12_ Expression Levels of Detoxification Enzyme Genes from Dendroctonus armandi (Coleoptera: Curculionidae) Fed on a Solid Diet Containing Pine Phloem and Terpenoids
Elgueta_2021_Toxics_9_ Analysis of Multi-Pesticide Residues and Dietary Risk Assessment in Fresh Tomatoes (Lycopersicum esculentum) from Local Supermarkets of the Metropolitan Region, Chile
Ferraz_2021_Int.J.Environ.Res.Public.Health_18_ Melanin: Production from Cheese Bacteria, Chemical Characterization, and Biological Activities
Ganeshpurkar_2021_J.Biomol.Struct.Dyn__1 Development of homology model, docking protocol and Machine-Learning based scoring functions for identification of Equus caballus's butyrylcholinesterase inhibitors
Gowler_2021_Arthritis.Rheumatol__ Clinical and preclinical evidence for roles of soluble epoxide hydrolase in osteoarthritis knee pain
Hamdeh_2021_Aliment.Pharmacol.Ther__ Review article: drug-induced small bowel injury
Hassan_2021_Phytomedicine_93_153771 Health benefits and phenolic compounds of Moringa oleifera leaves: A comprehensive review
He_2021_Cell.Death.Dis_12_992 Deletion of soluble epoxide hydrolase suppressed chronic kidney disease-related vascular calcification by restoring Sirtuin 3 expression
Javadi_2021_Langmuir__ Enzymatic Hydrolysis of Triglycerides at the Water-Oil Interface Studied via Interfacial Rheology Analysis of Lipase Adsorption Layers
Jeong_2021_J.Fungi.(Basel)_7_ Potent and Selective Inhibitors of Human Monoamine Oxidase A from an Endogenous Lichen Fungus Diaporthe mahothocarpus
Jia_2021_J.Med.Chem__ Directionally Modified Fluorophores for Super-Resolution Imaging of Target Enzymes: A Case Study with Carboxylesterases
Kaygisiz_2021_Acta.Neuropsychiatr__1 The effects of galangin in prepulse inhibition test and experimental schizophrenia models
Khan_2021_Exp.Appl.Acarol__ Lethal and sublethal effects of emamectin benzoate on life-table and physiological parameters of citrus red mite, Panonychus citri
Leite_2021_Foods_10_ Chemical Profile and Evaluation of the Antioxidant and Anti-Acetylcholinesterase Activities of Annona squamosa L. (Annonaceae) Extracts
Li_2021_J.Clin.Invest__ sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae
Li_2021_Zhen.Ci.Yan.Jiu_46_851 [Acupuncture improves cognitive function of vascular dementia rats by regulating PI3K\/Akt\/mTOR pathway]
Lima_2021_J.Biomol.Struct.Dyn__1 Diterpene Sonderianin isolated from Croton blanchetianus exhibits acetylcholinesterase inhibitory action and anxiolytic effect in adult zebrafish (Danio rerio) by 5-HT system
Luca_2021_Antioxidants.(Basel)_10_ Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the Genus Piper
Lunguinho_2021_Vet.Parasitol_300_109594 Acaricidal and repellent activity of the essential oils of Backhousia citriodora, Callistemon viminalis and Cinnamodendron dinisii against Rhipicephalus spp
Luo_2021_Front.Mol.Neurosci_14_744845 Postsynaptic Neuroligin-1 Mediates Presynaptic Endocytosis During Neuronal Activity
Ma_2021_Mikrochim.Acta_188_392 Point-of-care testing of butyrylcholinesterase activity through modulating the photothermal effect of cuprous oxide nanoparticles
Mennillo_2021_Drug.Metab.Dispos__ Intestinal UGT1A1 and protection against Irinotecan-induced toxicity in a novel UGT1A1 tissue-specific humanized mouse model
Nadeem_2021_Int.J.Biol.Macromol_193_19 Fluoxetine and sertraline based multitarget inhibitors of cholinesterases and monoamine oxidase-A\/B for the treatment of Alzheimer's disease: Synthesis, pharmacology and molecular modeling studies
Nascimento_2021_Biol.Trace.Elem.Res__ Children Environmentally Exposed to Agrochemicals in Rural Areas Present Changes in Oxidative Status and DNA Damage
Northington_2021_J.Comp.Neurol__ Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia-ischemia
Onasanwo_2021_Metab.Brain.Dis__ Moringa oleifera-supplemented diet protect against cortico-hippocampal neuronal degeneration in scopolamine-induced spatial memory deficit in mice: role of oxido-inflammatory and cholinergic neurotransmission pathway
Pereira_2021_Chemosphere__132649 Response of biomarkers to metals, hydrocarbons and organochlorine pesticides contamination in crabs (Callinectes ornatus and C. bocourti) from two tropical estuaries (Sao Jose and Sao Marcos bays) of the Maranho State (northeastern Brazil)
Pradeep_2021_Front.Chem_9_741037 Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-Based Calculations and Anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived From Acorus Calamus Plant Extract
Rafeeq_2021_Biotechnol.Appl.Biochem__ Esterases as emerging biocatalysts-mechanistic insights, genomic and metagenomic, immobilization and biotechnological applications
Rahman_2021_PLoS.One_16_e0258201 Case Study Using Recommended Reference Genes Actin and 18S for Reverse-Transcription Quantitative Real-Time PCR Analysis in Myzus persicae
Rants'o_2021_J.Mol.Graph.Model_110_108054 Optimization of covalent docking for organophosphates interaction with Anopheles acetylcholinesterase
Repp_2021_Nanomaterials.(Basel)_11_ Oligo(Lactic Acid)(8)-Docetaxel Prodrug-Loaded PEG-b-PLA Micelles for Prostate Cancer
Seguy_2021_Pharmaceutics_13_ Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer's Disease Treatment
Sinan_2021_Antioxidants.(Basel)_10_1570 LC-MS Based Analysis and Biological Properties of Pseudocedrela kotschyi (Schweinf.) Harms Extracts: A Valuable Source of Antioxidant, Antifungal, and Antibacterial Compounds
Sirichaiwetchakoon_2021_Evid.Based.Complement.Alternat.Med_2021_2703138 Butea superba Roxb. Extract Ameliorates Scopolamine-Induced Cognitive and Memory Impairment in Aged Male Rats
Souza_2021_Aquat.Toxicol_241_105997 Temporal exposure to malathion: Biochemical changes in the Amazonian fish tambaqui, Colossoma macropomum
Su_2021_J.Econ.Entomol__ Sublethal Effects of Abamectin on the Development, Reproduction, Detoxification Enzyme Activity, and Related Gene Expression of the Oriental Fruit Moth (Lepidoptera: Tortricidae)
Tian_2021_Neurochem.Int_150_105197 Soluble epoxide hydrolase inhibitor attenuates BBB disruption and neuroinflammation after intracerebral hemorrhage in mice
Uchigashima_2021_Front.Mol.Neurosci_14_749164 Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction
Walia_2021_Future.Oncol__ Genetic polymorphisms in the mEH gene in relation to tobacco smoking: role in lung cancer susceptibility and survival in north Indian patients with lung cancer undergoing platinum-based chemotherapy
Xiao_2021_Biotechnol.Lett__ An uncharacterized protein from the metagenome with no obvious homology to known lipases shows excellent alkaline lipase properties and potential applications in the detergent industry
Yu_2021_Phytochemistry_193_112982 Thirteen cyathane diterpenoids with acetylcholinesterase inhibitory effects from the fungus Cyathus africanus
Zengin_2021_Antioxidants.(Basel)_10_ Comprehensive Biological and Chemical Evaluation of Two Seseli Species (S. gummiferum and S. transcaucasicum)
Zhang_2021_J.Microbiol.Immunol.Infect__ Attenuation of virulence in multiple serotypes (M1, M3, and M28) of Group A Streptococcus after the loss of secreted esterase
Zhao_2021_Molecules_26_ Chemical Composition and Biological Activities of Essential Oils from the Leaves, Stems, and Roots of Kadsura coccinea
Zheleva-Dimitrova_2021_Plants.(Basel)_10_ Innovative Biochemometric Approach to the Metabolite and Biological Profiling of the Balkan Thistle (Cirsium appendiculatum Griseb.), Asteraceae
Zhou_2021_Biosens.Bioelectron_196_113723 Dual-fiber optic bioprobe system for triglyceride detection using surface plasmon resonance sensing and lipase-immobilized magnetic bead hydrolysis
Zhu_2021_Biosensors.(Basel)_11_ Nanozyme-Participated Biosensing of Pesticides and Cholinesterases: A Critical Review
Afsa_2021_Environ.Sci.Pollut.Res.Int__ A multi-biomarker approach for the early assessment of the toxicity of hospital wastewater using the freshwater organism Daphnia magna
Chen_2021_Front.Neurol_12_719849 Diagnosis and Treatment for Mild Cognitive Impairment: A Systematic Review of Clinical Practice Guidelines and Consensus Statements
de Almeida_2021_Mini.Rev.Med.Chem__ A Review on the in vitro Evaluation of the Anticholinesterase Activity Based on Ellman's Method
de Oliveira Pereira_2021_Neurotoxicol__ Dihydropyrimidinone-derived selenoesters efficacy and safety in an in vivo model of Abeta aggregation
Engler_2021_Drugs.Today.(Barc)_57_607 Evinacumab to treat hypercholesterolemia
Hu_2021_J.Clin.Neurosci_91_159 Association of EPHX1 polymorphisms with plasma concentration of carbamazepine in epileptic patients: Systematic review and meta-analysis
Ishimota_2021_Environ.Sci.Pollut.Res.Int__ Possible enzymatic mechanism underlying chemical tolerance and characteristics of tolerant population in Scapholeberis kingi
Kitazawa_2021_Biol.Pharm.Bull_44_1717 A Novel Function of Sphingosylphosphorylcholine on the Inhibitory Effects of Acetylcholinesterase Activity
Koganezawa_2021_Biochem.Biophys.Res.Commun_582_144 Super-resolved 3D-STED microscopy identifies a layer-specific increase in excitatory synapses in the hippocampal CA1 region of Neuroligin-3 KO mice
Kovrov_2021_J.Lipid.Res__100144 Lipoprotein size is a main determinant for the rate of hydrolysis by exogenous lipoprotein lipase in human plasma
Kumar_2021_Anal.Biochem_633_114402 Fluorimetric method for specific detection of human serum albumin in urine using its pseudoesterase property
Kumar_2021_Neurochem.Int_151_105217 Arbutin attenuates monosodium L-glutamate induced neurotoxicity and cognitive dysfunction in rats
Li_2021_Anim.Biosci__ mTOR and ERK1\/2 signaling participate in the process of acetate regulating lipid metabolism and HSL expression
Lv_2021_BMC.Plant.Biol_21_501 Genome-wide identification of the tobacco GDSL family and apical meristem-specific expression conferred by the GDSL promoter
Martelli_2021_Front.Genet_12_720552 hGATA1 Under the Control of a LCR\/beta-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced by the Gata1 (low) Mutation in Mice
Milech_2021_Vet.Med.Int_2021_5515559 Effects of Heated Pneumoperitoneum on Inflammation, Oxidative Stress, and Peritoneal Histology in Female Dogs That Underwent Video-Assisted Ovariohysterectomy
Moricz_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1185_123004 Acetylcholinesterase inhibitors in the giant goldenrod root
Neumann_2021_BMC.Neurol_21_422 Cholinesterase inhibitor to prevent falls in Parkinson's disease (CHIEF-PD) trial: a phase 3 randomised, double-blind placebo-controlled trial of rivastigmine to prevent falls in Parkinson's disease
Nkpaa_2021_Psychopharmacology.(Berl)__ Selenium abates manganese-induced striatal and hippocampal toxicity via abrogation of neurobehavioral deficits, biometal accumulation, oxidative stress, inflammation, and caspase-3 activation in rats
Paiva_2021_Chem.Rev_121_9502 Animal Fatty Acid Synthase: A Chemical Nanofactory
Parween_2021_PLoS.One_16_e0258879 Association between human paraoxonase 2 protein and efficacy of acetylcholinesterase inhibiting drugs used against Alzheimer's disease
Pham_2021_Chem.Res.Toxicol__ Using High-Throughput Screening to Evaluate Perturbations Potentially Linked to Neurobehavioral Outcomes: A Case Study Using Publicly Available Tools on FDA Batch-Certified Synthetic Food Dyes
Rehuman_2021_ACS.Omega_6_28182 Halogenated Coumarin-Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors
Rostami-Mansoor_2021_Int.J.Mol.Cell.Med_10_149 Modulation of mRNA Expression of Monoacylglycerol Lipase, Diacylglycerol Lipase and Cannabinoid Receptor-1 in Mice Experimentally Infected with T. gondii
Ruff_2021_Arterioscler.Thromb.Vasc.Biol__ATVBAHA120315757 LEGACY: Phase 2a Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of the Anti-EL (Endothelial Lipase) Antibody MEDI5884 in Patients With Stable Coronary Artery Disease
Ruzov_2021_Vopr.Kurortol.Fizioter.Lech.Fiz.Kult_98_32 [Serum concentration of phospholipase A2 and platelet aggregation during hyperbaric oxygen therapy in patients with ischemic heart disease]
Santos_2021_Aquat.Toxicol_241_106003 Influence of salinity on the toxicity of copper and cadmium to Zebrafish embryos
Song_2021_Anal.Chem__ Sensitivity Dependence on the Crystal Forms of a Fluorescence Quencher for Silicon Quantum Dots and Its Use in Acetylcholinesterase Assay
Stojanovic_2021_J.Ethnopharmacol__114788 Lemon balm (Melissa officinalis L.) essential oil and citronellal modulate anxiety-related symptoms - In vitro and in vivo studies
Thakkar_2021_Mol.Biol.Rep__ Impact of chronic sub-lethal methylparaben exposure on cardiac hypoxia and alterations in neuroendocrine factors in zebrafish model
Tian_2021_J.Med.Chem__ Triglyceride-Mimetic Structure-Gated Prodrug Nanoparticles for Smart Cancer Therapy
Xiao_2021_Langmuir__ Enzyme-Responsive Aqueous Two-Phase Systems in a Cationic-Anionic Surfactant Mixture
Xie_2021_Cell.Death.Dis_12_1003 Cardiac-specific CGI-58 deficiency activates the ER stress pathway to promote heart failure in mice
Xu_2021_J.Agric.Food.Chem_69_13102 Efficient Enzymatic Synthesis of Lipophilic Phenolic Glycoside Azelaic Acid Esters and Their Depigmenting Activity
Yang_2021_Plant.Cell__ Misregulation of MYB16 expression causes stomatal cluster formation by disrupting polarity during asymmetric cell divisions
Abdelsayed_2021_J.Food.Biochem__e13992 Niazimicin: A thiocarbamate glycoside from Moringa oleifera Lam. seeds with a novel neuroprotective activity
Basha_2021_Int.J.Biol.Macromol__ Deciphering the AChE-binding mechanism with multifunctional tricyclic coumarin anti-Alzheimer's agents using biophysical and bioinformatics approaches and evaluation of their modulating effect on Amyloidogenic peptide assembly
Boos_2021_Med.Chem.Res_30_1166 Dual monoamine oxidase B and acetylcholine esterase inhibitors for treating movement and cognition deficits in a C. elegans model of Parkinson's disease
Cadez_2021_Sci.Rep_11_21486 Assessment of four organophosphorus pesticides as inhibitors of human acetylcholinesterase and butyrylcholinesterase
da Costa Rodrigues_2021_Chem.Biol.Interact_351_109736 A new arylsulfanyl-benzo-2,1,3-thiadiazoles derivative produces an anti-amnesic effect in mice by modulating acetylcholinesterase activity
Haghighijoo_2021_Eur.J.Med.Chem_227_113949 Therapeutic potential of quinazoline derivatives for Alzheimer's disease: A comprehensive review
Heise_2021_Eur.J.Med.Chem_227_113947 N-methylated diazabicyclo[3.2.2]nonane substituted triterpenoic acids are excellent, hyperbolic and selective inhibitors for butyrylcholinesterase
Hu_2021_Sci.Rep_11_21639 Explainable machine learning model for predicting spontaneous bacterial peritonitis in cirrhotic patients with ascites
Li_2021_Food.Chem_373_131285 Molecular dynamics revealed the effect of epoxy group on triglyceride digestion
Liu_2021_Nat.Prod.Res__1 Two new organic acids from Portulaca oleracea L. and their anti-inflammatory and anticholinesterase activities
Liu_2021_Eur.J.Med.Chem_227_113973 Design, synthesis, and biological evaluation of novel (4-(1,2,4-oxadiazol-5-yl)phenyl)-2-aminoacetamide derivatives as multifunctional agents for the treatment of Alzheimer's disease
Manayi_2021_Nat.Prod.Res__1 Phytochemical investigation and biological activity of Doronicum pardalianches L. roots against Alzheimer's disease
Mooney-Leber_2021_Front.Psychiatry_12_737897 Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains
Morozov_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109240 Biochemical and respiratory parameters in a gastropod Radix balthica exposed to diclofenac
Muhammed_2021_Toxicol.Res.(Camb)_10_983 Toxicity and biochemical responses induced by phosmet in rainbow trout (Oncorhynchus mykiss)
Olayinka_2021_Metab.Brain.Dis__ Quercetin mitigates scopolamine-induced memory dysfunction: impact on oxidative stress and cholinergic mechanisms
Pang_2021_Front.Pharmacol_12_737764 Securidaca inappendiculata Polyphenol Rich Extract Counteracts Cognitive Deficits, Neuropathy, Neuroinflammation and Oxidative Stress in Diabetic Encephalopathic Rats via p38 MAPK\/Nrf2\/HO-1 Pathways
Paredes-Ruiz_2021_Neurotox.Res__ On the Biomedical Properties of Endocannabinoid Degradation and Reuptake Inhibitors: Pre-clinical and Clinical Evidence
Peng_2021_Phytomedicine_93_153772 Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota
Quinn_2021_Eur.Stroke.J_6_I European Stroke Organisation and European Academy of Neurology joint guidelines on post-stroke cognitive impairment
Salau_2021_Arch.Physiol.Biochem__1 Vanillin improves glucose homeostasis and modulates metabolic activities linked to type 2 diabetes in fructose-streptozotocin induced diabetic rats
Santos_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_252_109225 Acetylcholinesterase from the charru mussel Mytella charruana: kinetic characterization, physicochemical properties and potential as in vitro biomarker in environmental monitoring of mollusk extraction areas
Shah_2021_J.Biomol.Struct.Dyn__1 Insights into the structural requirements of triazole derivatives as promising DPP IV inhibitors: computational investigations
Shariati_2021_Biodegradation__ Degradation of dibutyl phthalate by Paenarthrobacter sp. Shss isolated from Saravan landfill, Hyrcanian Forests, Iran
Shi_2021_Clin.Pharmacol.Ther__ Plasma carboxylesterase 1 predicts methylphenidate exposure: a proof-of-concept study using plasma protein biomarker for hepatic drug metabolism
Singha_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_252_109223 Influence of dietary emamectin benzoate on the biological responses of monosex (all-male) Oreochromis niloticus (L.) fries
Song_2021_Acta.Pharm.Sin.B_11_3035 Recent developments in the medicinal chemistry of single boron atom-containing compounds
Wang_2021_Fitoterapia_156_105069 Japonisine A, a fawcettimine-type Lycopodium alkaloid with an unusual skeleton from Lycopodium japonicum Thunb
Xin_2021_Arch.Insect.Biochem.Physiol__e21850 Construction and analysis of the protein-protein interaction network for the detoxification enzymes of the silkworm, Bombyx mori
Yu_2021_Bioorg.Chem_117_105404 Acylphloroglucinol trimers from Callistemon salignus seeds: Isolation, configurational assignment, hAChE inhibitory effects, and molecular docking studies
Zaki_2021_Appl.Microbiol.Biotechnol__ New and potent production platform of the acetylcholinesterase inhibitor huperzine A by gamma-irradiated Alternaria brassicae under solid-state fermentation
Ahmad_2021_Saudi.J.Biol.Sci_28_6352 Evaluation of analgesic, antiamnesic and antidiarrheal potentials of Medicago denticulata extract using animal model
Bakkes_2021_Front.Microbiol_12_750150 Biosensor-Based Optimization of Cutinase Secretion by Corynebacterium glutamicum
Bhanderi_2021_Materials.(Basel)_14_ Optimized Rivastigmine Nanoparticles Coated with Eudragit for Intranasal Application to Brain Delivery: Evaluation and Nasal Ciliotoxicity Studies
Birdane_2021_Environ.Sci.Pollut.Res.Int__ The protective effects of erdosteine on subacute diazinon-induced oxidative stress and inflammation in rats
Biswas_2021_Drug.Chem.Toxicol__1 Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain
Campos_2021_Toxicology__153033 Protective Effects of Chrysin against the Neurotoxicity Induced by Aluminium: In Vitro and In Vivo Studies
Castle_2021_Sci.Total.Environ__151280 High nutritional status promotes vitality of honey bees and mitigates negative effects of pesticides
Demir-Yazici_2021_Future.Med.Chem__ Synthesis, molecular modeling and cholinesterase inhibitory effects of 2-indolinone-based hydrazinecarbothioamides
Dymek_2021_Molecules_26_6379 Fractionation of Lycopodiaceae Alkaloids and Evaluation of Their Anticholinesterase and Cytotoxic Activities
Friedli_2021_Molecules_26_ Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer's Disease
Ganesh_2021_Neurology_97_964 Editors' Note: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Goncalves_2021_Molecules_26_ Impact of Metallic Nanoparticles on In Vitro Culture, Phenolic Profile and Biological Activity of Two Mediterranean Lamiaceae Species: Lavandula viridis L'Her and Thymus lotocephalus G. Lopez and R. Morales
Gulcan_2021_Curr.Top.Med.Chem__ The hybrid compounds as multi-target ligands for the treatment of Alzheimer's Disease: Considerations on Donepezil
Han_2021_J.Asian.Nat.Prod.Res__1 Citrinin and alpha-pyrone derivatives with pancreatic lipase inhibitory activities from Penicillium sp. SCSIO 41302
Hanslik_2021_Sci.Total.Environ__151640 Rethinking the relevance of microplastics as vector for anthropogenic contaminants: Adsorption of toxicants to microplastics during exposure in a highly polluted stream - Analytical quantification and assessment of toxic effects in zebrafish (Danio rerio)
Herriage_2021_Toxicol.In.Vitro_78_105268 Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells
Hossain_2021_Heliyon_7_e08285 Heavy metal toxicity in Buriganga river alters the immunology of Nile tilapia (Oreochromis niloticus L)
Kinchen_2021_J.Proteome.Res__ Long-Chain Acylcholines Link Butyrylcholinesterase to Regulation of Non-neuronal Cholinergic Signaling
Kuschpel_2021_Neurology_97_964 Reader Response: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Liu_2021_Molecules_26_ Discovery of Guanidine Derivatives from Buthus martensii Karsch with Metal-Binding and Cholinesterase Inhibition Properties
Nenaah_2021_Pest.Manag.Sci__ The essential oil of Schinus terebinthifolius and its nanoemulsion and isolated monoterpenes: Investigation of their activity against Culex pipiens with insights into the adverse effects on non-target organisms
Paprottka_2021_Cancers.(Basel)_13_ Outcome and Safety after 103 Radioembolizations with Yttrium-90 Resin Microspheres in 73 Patients with Unresectable Intrahepatic Cholangiocarcinoma-An Evaluation of Predictors
Pereira_2021_Molecules_26_ Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights
Sellami_2021_Saudi.J.Biol.Sci_28_6365 Impacts of nanoparticles and phosphonates in the behavior and oxidative status of the mediterranean mussels (Mytilus galloprovincialis)
Sudeep_2021_J.Food.Biochem__e13994 A standardized black pepper seed extract containing beta-caryophyllene improves cognitive function in scopolamine-induced amnesia model mice via regulation of brain-derived neurotrophic factor and MAPK proteins
Tigges_2021_Arch.Toxicol__ Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense
Wiegmann_2021_Int.J.Parasitol.Parasites.Wildl_16_236 The prevalence of Leucocytozoon spp. in nestlings of three wild raptor species including implications on haematological and blood chemistry values
Xu_2021_Neurology_97_965 Author Response: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Yan_2021_Anim.Dis_1_15 The nucleoside antiviral prodrug remdesivir in treating COVID-19 and beyond with interspecies significance
Yavari_2021_J.Biochem.Mol.Toxicol__e22952 Synthesis and some enzyme inhibition effects of isoxazoline and pyrazoline derivatives including benzonorbornene unit
Yunusa_2021_J.Alzheimers.Dis.Rep_5_705 Comparative Value of Cholinesterase Inhibitors and Memantine in Persons with Moderate-to-Severe Alzheimer's Disease in the United States: A Cost-Effectiveness Analysis
Zaib_2021_Molecules_26_ Hybrid Quinoline-Thiosemicarbazone Therapeutics as a New Treatment Opportunity for Alzheimer's Disease-Synthesis, In Vitro Cholinesterase Inhibitory Potential and Computational Modeling Analysis
Attarroshan_2021_Chem.Biodivers__ Imino-2H-chromene based derivatives as potential anti-Alzheimer's agents: Design, synthesis, biological evaluation and in silico study
Bilal_2021_Bioelectrochemistry_144_107999 Assessment of pesticide induced inhibition of Apis mellifera (honeybee) acetylcholinesterase by means of N-doped carbon dots\/BSA nanocomposite modified electrochemical biosensor
Bonfanti-Azzolin_2021_Toxicol.Ind.Health__7482337211053164 Accelerated apoptosis, oxidative stress, and cholinergic inflammation in blood of metalworkers
Brandao_2021_ACS.Med.Chem.Lett_12_1718 Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors
Camargo_2021_Rev.Soc.Bras.Med.Trop_54_e0201 Influence of galantamine in the inflammatory process and tissular lesions caused by Trypanosoma cruzi QM2 strain
Dhami_2021_Curr.Alzheimer.Res__ Neuroprotective Effect of Fucoxanthin against Intracerebroventricular Streptozotocin (ICV-STZ) Induced Cognitive Impairment in Experimental Rats
Franca_2021_Nat.Prod.Res__1 Chemical composition, in vitro cytotoxic and anticholinesterase activities of flower extracts of Senna spectabilis var. excelsa and Senna macranthera
Gunsel_2021_J.Biomol.Struct.Dyn__1 Novel tetrakis-phthalocyanines bearing pyrimidine derivative: crystal XRD analysis, enzyme inhibition, molecular docking, and anticancer effects
Hermansyah_2021_Comput.Biol.Chem_95_107597 Virtual screening of dipeptidyl peptidase-4 inhibitors using quantitative structure-activity relationship-based artificial intelligence and molecular docking of hit compounds
Kamdi_2021_Eur.J.Pharmacol__174645 Ameliorative potential of phloridzin in type 2 diabetes-induced memory deficit in rats
Kaur_2021_Bioorg.Chem_118_105479 Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity
Kumar_2021_Curr.Drug.Targets__ A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer's Disease
Kundo_2021_Biomed.Res.Int_2021_9154406 Identification of Polyphenolics from Loranthus globosus as Potential Inhibitors of Cholinesterase and Oxidative Stress for Alzheimer's Disease Treatment
Meira_2021_ACS.Chem.Neurosci__ Binding Mechanism between Acetylcholinesterase and Drugs Pazopanib and Lapatinib: Biochemical and Biophysical Studies
Nawaz_2021_J.Parkinsons.Dis__ Anticholinergic Medication Burden in Parkinson's Disease Outpatients
Oliveira_2021_Pharmacol.Biochem.Behav_211_173300 Scopolamine and MK-801 impair recognition memory in a new spontaneous object exploration task in monkeys
Oviedo-Sarmiento_2021_Pestic.Biochem.Physiol_179_104941 Fumigant toxicity and biochemical effects of selected essential oils toward the red flour beetle, Tribolium castaneum (Coleoptera: Tenebrionidae)
Patterson_2021_Immune.Netw_21_e35 IL-17 and IL-17C Signaling Protects the Intestinal Epithelium against Diisopropyl Fluorophosphate Exposure in an Acute Model of Gulf War Veterans' Illnesses
Raza_2021_J.Thorac.Dis_13_6187 Robotic thymectomy for myasthenia gravis surgical techniques and outcomes
Reale_2021_J.Alzheimers.Dis__ Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia with Lewy Bodies from Alzheimer's Disease
Saleem_2021_Bioorg.Chem_118_105457 Deep eutectic solvent mediated synthesis of 3,4-dihydropyrimidin-2(1H)-ones and evaluation of biological activities targeting neurodegenerative disorders
Samad_2021_Pak.J.Pharm.Sci_34_1499 Tryptophan lessens reserpine induced anxiety, depression and memory impairment by modulating oxidative stress and serotonergic activity
Senocak_2021_J.Biochem.Mol.Toxicol__e22969 Novel amino acid Schiff base Zn(II) complexes as new therapeutic approaches in diabetes and Alzheimer's disease: Synthesis, characterization, biological evaluation, and molecular docking studies
Tayanloo-Beik_2021_J.Mol.Neurosci__ Paeonol Ameliorates Cognitive Deficits in Streptozotocin Murine Model of Sporadic Alzheimer's Disease via Attenuation of Oxidative Stress, Inflammation, and Mitochondrial Dysfunction
Vrabec_2021_Phytochemistry_194_113017 Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease
Wang_2021_Angew.Chem.Int.Ed.Engl__ Enzyme Control Over Ferric Iron Magnetostructural Properties
Wang_2021_Ecotoxicol.Environ.Saf_228_112959 The cholinergic system, intelligence, and dental fluorosis in school-aged children with low-to-moderate fluoride exposure
Wolie_2021_Parasit.Vectors_14_581 Evaluation of the interaction between insecticide resistance-associated genes and malaria transmission in Anopheles gambiae sensu lato in central Cte d'Ivoire
Zhan_2021_Pestic.Biochem.Physiol_179_104973 Influence of three insecticides targeting GABA receptor on fall armyworm Spodoptera frugiperda: Analyses from individual, biochemical and molecular levels
Zhang_2021_Front.Oncol_11_630257 Clinical Relevance and Prognostic Value of the Neuronal Protein Neuroligin 2 in Breast Cancer
Ahmaditabatabaei_2021_J.Fungi.(Basel)_7_ Fungal Enzymes as Catalytic Tools for Polyethylene Terephthalate (PET) Degradation
Bhattacharyya_2021_Environ.Microbiol.Rep__ Phthalate hydrolase: distribution, diversity and molecular evolution
Brown_2021_Cell_184_5886 From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease
Cacciatore_2021_RSC.Med.Chem_12_1944 Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties
Chahouri_2021_Mar.Pollut.Bull_174_113179 Assessment of seasonal and spatial variation responses of integrated biomarkers in two marine sentinel bivalve species: Agadir Bay (Southern of Morocco)
Chen_2021_NPJ.Parkinsons.Dis_7_103 Cholinesterase inhibitors for gait, balance, and fall in Parkinson disease: a meta-analysis
Crowther_2021_BJPsych.Bull__1 Cardiac monitoring in memory clinics: national survey of UK practice
Cunha_2021_J.Hazard.Mater__127753 From carrion-eaters to plastic material plunderers: Toxicological impacts of plastic ingestion on black vultures, Coragyps atratus (Cathartiformes: Cathartidae)
Dao_2021_Animals.(Basel)_11_ Understanding the Role of Prevotella Genus in the Digestion of Lignocellulose and Other Substrates in Vietnamese Native Goats' Rumen by Metagenomic Deep Sequencing
Djafarou_2021_J.Biomol.Struct.Dyn__1 Computational design of new tacrine analogs: an in silico prediction of their cholinesterase inhibitory, antioxidant, and hepatotoxic activities
El-Nashar_2021_Molecules_26_ GC\/MS Analysis of Essential Oil and Enzyme Inhibitory Activities of Syzygium cumini (Pamposia) Grown in Egypt: Chemical Characterization and Molecular Docking Studies
Fan_2021_Foods_10_ Accelerated Solvent Extraction of Antioxidant Compounds from Gardeniae Fructus and Its Acetylcholinesterase Inhibitory and PC12 Cell Protective Activities
Gavril_2021_Medicina.(Kaunas)_57_1249 Correlations between PNPLA3 Gene Polymorphisms and NAFLD in Type 2 Diabetic Patients
Gavril_2021_Medicina.(Kaunas)_57_1153 Role of PNPLA3 in the Assessment and Monitoring of Hepatic Steatosis and Fibrosis in Patients with Chronic Hepatitis C Infection Who Achieved a Sustained Virologic Response
Huang_2021_Cells_10_ Multi-Target Effects of Novel Synthetic Coumarin Derivatives Protecting Abeta-GFP SH-SY5Y Cells against Abeta Toxicity
Issotina_2021_Int.Immunopharmacol__108365 Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia
Jahangirfard_2021_Vet.Res.Forum_12_333 Ethephon causes reproductive malfunction in adult male mice: Histological and biochemical evidence
Jamshidnejad-Tosaramandani_2021_Pharmaceuticals.(Basel)_14_ The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro
John_2021_J.Mass.Spectrom.Adv.Clin.Lab_19_20 Poisoning by organophosphorus nerve agents and pesticides: An overview of the principle strategies and current progress of mass spectrometry-based procedures for verification
Kashi_2021_Food.Chem.X_12_100163 Optimization of extraction conditions and determination of the Chlorpyrifos, Diazinon, and malathion residues in environment samples: Fruit (Apple, Orange, and Tomato)
Malgas_2021_Molecules_26_ Unraveling Synergism between Various GH Family Xylanases and Debranching Enzymes during Hetero-Xylan Degradation
Mlakic_2021_Pharmaceuticals.(Basel)_14_ New Uncharged 2-Thienostilbene Oximes as Reactivators of Organophosphate-Inhibited Cholinesterases
Moncaleano-Nino_2021_Environ.Sci.Pollut.Res.Int__ Monitoring metallothionein-like protein concentrations and cholinesterase activity in tropical cup oysters as biomarkers of exposure to metals and pesticides in the southern Caribbean, Colombia
Moreta_2021_Biomedicines_9_ Efficacy of Acetylcholinesterase Inhibitors on Cognitive Function in Alzheimer's Disease. Review of Reviews
Mottaghipisheh_2021_Pharmaceuticals.(Basel)_14_ Linarin, a Glycosylated Flavonoid, with Potential Therapeutic Attributes: A Comprehensive Review
Muellerleile_2021_Mol.Neurobiol__ Neuroligin-3 Regulates Excitatory Synaptic Transmission and EPSP-Spike Coupling in the Dentate Gyrus In Vivo
Musaeus_2021_Curr.Alzheimer.Res__ Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review
Quratulain_2021_Pak.J.Pharm.Sci_34_1989 Synthesis, characterization, SAR, antioxidant, anti-acetylcholinesterase and anti-butyrylcholinesterase activities of cephradine Schiff bases
Rafat_2021_Biosensors.(Basel)_11_ Electrochemical Biosensor for Markers of Neurological Esterase Inhibition
Shi_2021_Hepatol.Int__ Mesenchymal stem cell therapy in decompensated liver cirrhosis: a long-term follow-up analysis of the randomized controlled clinical trial
Sinan_2021_Antioxidants.(Basel)_10_1771 Exploring the Chemical Profiles and Biological Values of Two Spondias Species (S. dulcis and S. mombin): Valuable Sources of Bioactive Natural Products
Singh_2021_Chem.Res.Toxicol__ New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation
Uckun_2021_Environ.Sci.Pollut.Res.Int__ Assessing the toxic effects of bisphenol A in consumed crayfish Astacus leptodactylus using multi biochemical markers
Vasamsetti_2021_Genes.(Basel)_12_ Transcriptome-Based Identification of Genes Responding to the Organophosphate Pesticide Phosmet in Danio rerio
Wei_2021_Fitoterapia__105090 Structurally diverse Monascus pigments with hypolipidemic and hepatoprotective activities from highland barley Monascus
Xiang_2021_Foods_10_ UPLC-MS\/MS Profiling, Antioxidant, alpha-Glucosidase Inhibitory, Cholinesterase Inhibitory, and Cardiovascular Protection Potentials of Jialing 20 (Morus multicaulis Perr.) Mulberry Branch Extract
Yang_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_253_109248 Neurotoxicity induced by combined exposure of microcystin-LR and nitrite in male zebrafish (Danio rerio): Effects of oxidant-antioxidant system and neurotransmitter system
Yilmaz_2021_J.Biomol.Struct.Dyn__1 Unravelling the phenolic compound reserves, antioxidant and enzyme inhibitory activities of an endemic plant species, Achillea pseudoaleppica
Zhang_2021_Int.J.Mol.Sci_22_ Genome-Wide Identification of GDSL-Type Esterase\/Lipase Gene Family in Dasypyrum villosum L. Reveals That DvGELP53 Is Related to BSMV Infection
Aboelhadid_2021_PLoS.One_16_e0260172 Acaricidal activity of Foeniculum vulgare against Rhipicephalus annulatus is mainly dependent on its constituent from trans-anethone
Ansari_2021_Arch.Pharm.(Weinheim)__e2100376 Biology-oriented drug synthesis and evaluation of secnidazole esters as novel enzyme inhibitors
Anupama_2021_J.Biomol.Struct.Dyn__1 Jatamansinol from Nardostachys jatamansi: a multi-targeted neuroprotective agent for Alzheimer's disease
Balazs_2021_Ideggyogy.Sz_74_379 Cholinesterase inhibitors and memantine for the treatment of Alzheimer and non-Alzheimer dementias
Barut_2021_Turk.J.Chem_45_1567 Pyridine substituted BODIPYs: synthesis, characterization and cholinesterease, alpha-glucosidase inhibitory, DNA hydrolytic cleavage effects
Benham-Pyle_2021_Nat.Cell.Biol_23_939 Identification of rare, transient post-mitotic cell states that are induced by injury and required for whole-body regeneration in Schmidtea mediterranea
Bottasso_2021_Am.J.Physiol.Lung.Cell.Mol.Physiol__ BMP4 and WNT signaling interact to promote mouse tracheal mesenchyme morphogenesis
Cassano_2021_Clin.Mol.Allergy_19_24 Angioedema associated with dipeptidyl peptidase-IV inhibitors
Chen_2021_J.Am.Med.Dir.Assoc__ Alzheimer's Disease THErapy With NEuroaid (ATHENE): A Randomized Double-Blind Delayed-Start Trial
Chen_2021_Chem.Biodivers__e2100443 Essential Oils from Spices Inhibit Cholinesterase Activity and Improve Behavioral Disorder in AlCl(3) Induced Dementia
Estevez_2021_Chem.Biol.Interact__109764 Interactions of human acetylcholinesterase with phenyl valerate and acetylthiocholine: Thiocholine as an enhancer of phenyl valerate esterase activity
Forcada_2021_PLoS.One_16_e0259939 A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats
Guo_2021_Sci.Rep_11_16409 NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice
Huang_2021_Sci.Total.Environ__152107 Accelerated biodegradation of polyethylene terephthalate by Thermobifida fusca cutinase mediated by Stenotrophomonas pavanii
Islam_2021_ACS.Omega_6_31539 Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors
Johnson_2021_Biochem.Biophys.Rep_28_101175 Biochemical evaluation and molecular docking assessment of Cymbopogon citratus as a natural source of acetylcholine esterase (AChE)- targeting insecticides
Kondak_2021_J.Neurochem__ Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine
Krishnendu_2021_Curr.Top.Med.Chem__ Formulating The Structural Aspects Of Various Benzimidazole Cognates
Lan_2021_J.Chem.Inf.Model__ Glycerol is Released from a New Path in MGL Lipase Catalytic Process
Liu_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc__120665 Monitoring of parathion methyl using a colorimetric gold nanoparticle-based acetylcholinesterase assay
Liu_2021_Plant.Foods.Hum.Nutr__ Elsholtzia rugulosa: Phytochemical Profile and Antioxidant, Anti-Alzheimer's Disease, Antidiabetic, Antibacterial, Cytotoxic and Hepatoprotective Activities
Liu_2021_Aquat.Toxicol_242_106039 Chlorogenic acid alleviates thioacetamide-induced toxicity and promotes liver development in zebrafish (Danio rerio) through the Wnt signaling pathway
Ma_2021_Mol.Immunol_141_108 The protective effects of Omarigliptin against Lipopolysaccharide (LPS)- induced inflammatory response and expression of mucin 5AC (MUC5AC) in human bronchial epithelial cells
Malafaia_2021_J.Hazard.Mater__127873 Shedding light on the impacts of gestational exposure to polystyrene nanoplastics on the reproductive performance of Poecilia reticulata female and on the biochemical response of embryos
Meng_2021_Biomed.Res.Int_2021_4579850 A Network Pharmacology-Based Study on Irritable Bowel Syndrome Prevention and Treatment Utilizing Shenling Baizhu Powder
Muller-Vahl_2021_Pharmacopsychiatry__ Endocannabinoid Modulation Using Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A Phase 1 Randomized, Placebo-Controlled Study
Oe_2021_Chem.Commun.(Camb)__ An activator-induced quencher-detachment-based turn-on probe with a cationic substrate moiety for acetylcholinesterase
P_2021_J.Biol.Chem__101466 Cholinergic signalling at the body wall neuromuscular junction distally inhibits feeding behaviour in C. elegans
Pei_2021_Mikrochim.Acta_189_7 Fluorine-free synthesis of Ti(3)C(2) MQDs for smartphone-based fluorescent and colorimetric determination of acetylcholinesterase and organophosphorus pesticides
Ploug_2021_Curr.Opin.Lipidol__ ANGPTL4: a new mode in the regulation of intravascular lipolysis
Ranneh_2021_Saudi.J.Biol.Sci_28_6711 Anti-aging and antioxidant of four traditional malaysian plants using simplex centroid mixture design approach
Ren_2021_Eur.J.Med.Chem_228_114031 Imidazolylacetophenone oxime-based multifunctional neuroprotective agents: Discovery and structure-activity relationships
Sawarng_2021_J.Environ.Public.Health_2021_6746367 Effectiveness of a Participatory Program on Pesticide Use Behavior and Blood Cholinesterase Levels in Chiang Mai Province, Northern Thailand
Simonsen_2021_Toxicol.Sci__ The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL\/6 Mice
Suarez-Montenegro_2021_Front.Nutr_8_769617 Neuroprotective Potential of Tamarillo (Cyphomandra betacea) Epicarp Extracts Obtained by Sustainable Extraction Process
Sui_2021_Adv.Nanobiomed.Res_1_ Esterase-activatable and GSH-responsive Triptolide Nano-prodrug for the Eradication of Pancreatic Cancer
Ullah_2021_Ecotoxicol.Environ.Saf_228_113032 Heavy metals bioaccumulation and subsequent multiple biomarkers based appraisal of toxicity in the critically endangered Tor putitora
Wang_2021_Insect.Sci__ Influence of seasonal migration on evolution of insecticide resistance in Plutella xylostella
Wong_2021_Diabetes.Metab__101307 Use of DPP4i reduced odds of clinical deterioration and hyperinflammatory syndrome in COVID-19 patients with type 2 diabetes: propensity score analysis of a territory-wide cohort in Hong Kong
Yang_2021_Arch.Oral.Biol_130_105211 Notum suppresses the osteogenic differentiation of periodontal ligament stem cells through the Wnt\/Beta catenin signaling pathway
Yang_2021_Ann.Palliat.Med_10_11714 Cholinesterase level is a predictor of systemic inflammatory response syndrome and complications after cardiopulmonary bypass
Zhang_2021_Front.Cardiovasc.Med_8_795370 The Potential of ANGPTL8 Antagonism to Simultaneously Reduce Triglyceride and Increase HDL-Cholesterol Plasma Levels
Zhang_2021_BMC.Cancer_21_1156 Development and validation of genomic and epigenomic signatures associated with tumor immune microenvironment in hepatoblastoma
Zhao_2021_Bioorg.Chem_119_105520 Identification and synthesis of selective cholesterol esterase inhibitor using dynamic combinatorial chemistry
Wang_2021_Trends.Plant.Sci__ Origins of strigolactone and karrikin signaling in plants
Adhikari_2021_Toxicol.Rep_8_1883 Gradual reduction of susceptibility and enhanced detoxifying enzyme activities of laboratory-reared Aedes aegypti under exposure of temephos for 28 generations
Munoz-Najera_2021_Environ.Monit.Assess_194_23 Temporal and spatial analysis of benomyl\/carbendazim in water and its possible impact on Nile tilapia (Oreochromis niloticus) from Tenango dam, Puebla, Mexico
Alikhani_2021_Iran.J.Pharm.Res_20_560 Response Surface Study on Molecular Docking Simulations of Citalopram and Donepezil as Potent CNS Drugs
Baldini_2021_Mol.Biol.Evol__ Phylogenetic and molecular analyses identify SNORD116 targets involved in the Prader Willi syndrome
Bouwmeester_2021_Plant.Physiol_185_1292 Adaptation of the parasitic plant lifecycle: germination is controlled by essential host signaling molecules
Capatina_2021_Molecules_26_ Origanum vulgare ssp. hirtum (Lamiaceae) Essential Oil Prevents Behavioral and Oxidative Stress Changes in the Scopolamine Zebrafish Model
Celik_2021_Eur.J.Neurosci__ Therapeutic effects of carvacrol on beta-amyloid-induced impairments in in-vitro and in-vivo models of Alzheimer's disease
Ceyhun_2021_Arch.Pharm.(Weinheim)__e2100372 Design and synthesis of novel chalcone derivatives and evaluation of their inhibitory activities against acetylcholinesterase
Chen_2021_Biomed.Res.Int_2021_6607386 Risk Factors and a Nomogram Model Establishment for Postoperative Delirium in Elderly Patients Undergoing Arthroplasty Surgery: A Single-Center Retrospective Study
Chung_2021_World.J.Diabetes_12_1818 Organophosphate pesticides and new-onset diabetes mellitus: From molecular mechanisms to a possible therapeutic perspective
da Motta_2021_Chem.Biol.Interact__109772 Target enzymes in oxaliplatin-induced peripheral neuropathy in Swiss mice: A new acetylcholinesterase inhibitor as therapeutic strategy
Dassanayake_2021_Clin.Toxicol.(Phila)__1 Changes of attention-related brain activity over 6 months after acute organophosphate pesticide poisoning: a prospective follow-up study
Ding_2021_Nat.Metab__ Peroxisomal beta-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis
Faruk_2021_J.Neurochem__ Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning
Fisayo_2021_Food.Chem.X_12_100165 Identification and characterization of cholesterol esterase and lipase inhibitory peptides from amaranth protein hydrolysates
Granada_2021_PLoS.Negl.Trop.Dis_15_e0010001 Molecular surveillance of resistance to pyrethroids insecticides in Colombian Aedes aegypti populations
Gu_2021_J.Gene.Med__e3403 Silencing of circDPP4 suppresses cell progression of human prostate cancer and enhances docetaxel cytotoxicity through regulating miR-564\/ZIC2 axis
He_2021_Chirality__ Resolution of (R,S)-1-(4-methoxyphenyl)ethanol by lipase-catalyzed stereoselective transesterification and the process optimization
Hinkovska-Galcheva_2021_J.Lipid.Res_62_100089 Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis
Hussain_2021_Molecules_26_ Neuroprotective Potential of Synthetic Mono-Carbonyl Curcumin Analogs Assessed by Molecular Docking Studies
Ikeda_2021_World.J.Biol.Chem_12_104 Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagon-like peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer's disease
Imig_2021_Biochem.Pharmacol_195_114866 Epoxylipids and soluble epoxide hydrolase in heart diseases
Ismail_2021_Int.J.Biol.Macromol_187_127 Temperature-resistant and solvent-tolerant lipases as industrial biocatalysts: Biotechnological approaches and applications
Jia_2021_Front.Chem_9_780304 Acorenone C: A New Spiro-Sesquiterpene from a Mangrove-Associated Fungus, Pseudofusicoccum sp. J003
Kahlert_2021_Angew.Chem.Int.Ed.Engl_60_11423 Biosynthesis of 6-Hydroxymellein Requires a Collaborating Polyketide Synthase-like Enzyme
Kunkeaw_2021_Sci.Rep_11_23796 Diplazium esculentum (Retz.) Sw. reduces BACE-1 activities and amyloid peptides accumulation in Drosophila models of Alzheimer's disease
Lee_2021_Br.J.Pharmacol__ Alternative Pain Management via Endocannabinoids in the Time of the Opioid Epidemic: Peripheral Neuromodulation and Pharmacological Interventions
Liu_2021_Arch.Insect.Biochem.Physiol__e21859 Decreased carboxylesterase expression associated with increased susceptibility to insecticide in Mythimna separata
Liu_2021_J.Med.Chem_64_13853 Blood-Brain Barrier Permeable and NO-Releasing Multifunctional Nanoparticles for Alzheimer's Disease Treatment: Targeting NO\/cGMP\/CREB Signaling Pathways
Lopez_2021_Food.Funct__ Neuroprotective and anxiolytic potential of green rooibos (Aspalathus linearis) polyphenolic extract
Lourido_2021_Environ.Toxicol.Pharmacol__103783 Lethal and sublethal effects of the emerging contaminant oxytetracycline on the embryo-larval development of Rhinella arenarum
Maksimovic_2021_Drug.Chem.Toxicol__1 Acute organophosphate and carbamate pesticide poisonings - a five-year survey from the National Poison Control Center Of Serbia
Manickam_2021_Arch.Pharm.(Weinheim)__e2100367 Activating endogenous resolution pathways by soluble epoxide hydrolase inhibitors for the management of COVID-19
Martini_2021_Neurocrit.Care__ A Double-Blind, Randomized, Placebo-Controlled Trial of Soluble Epoxide Hydrolase Inhibition in Patients with Aneurysmal Subarachnoid Hemorrhage
Min_2021_CNS.Neurosci.Ther__ Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice
Muramatsu_2021_J.Neurochem__ Evaluation of radiolabeled acetylcholine synthesis and release in rat striatum
Mwagira-Maina_2021_Malar.J_20_461