Year

Tree Display

AceDB Schema

XML Display

Feedback

Year Report for: 2021

Aarsland_2021_Nat.Rev.Dis.Primers_7_47Parkinson disease-associated cognitive impairment
Abbad_2021_PLoS.One_16_e0258750Effect of identified non-synonymous mutations in DPP4 receptor binding residues among highly exposed human population in Morocco to MERS-CoV through computational approach
Abd_2021_Molecules_26_Essential Oils as a Potential Neuroprotective Remedy for Age-Related Neurodegenerative Diseases: A Review
Abdel-Aal_2021_Eur.J.Pharmacol_915_174695Naproxen as a potential candidate for promoting rivastigmine anti-Alzheimer activity against aluminum chloride-prompted Alzheimer's-like disease in rats; neurogenesis and apoptosis modulation as a possible underlying mechanism
Abdel-Salam_2021_Iran.J.Basic.Med.Sci_24_1437Inhibition of aluminum chloride-induced amyloid Abeta peptide accumulation and brain neurodegeneration by Bougainvillea spectabilis flower decoction
Abdelsalam_2021_J.Genet.Eng.Biotechnol_19_108Metabolic profiling, in vitro propagation, and genetic assessment of the endangered rare plant Anarrhinum pubescens
Abdelsayed_2021_J.Food.Biochem__e13992Niazimicin: A thiocarbamate glycoside from Moringa oleifera Lam. seeds with a novel neuroprotective activity
Abdollahdokht_2021_Environ.Sci.Pollut.Res.Int__Pesticide exposure and related health problems among farmworkers' children: a case-control study in southeast Iran
Abdou_2021_Environ.Sci.Pollut.Res.Int__Neurotoxicity and neuroinflammatory effects of bisphenol A in male rats: the neuroprotective role of grape seed proanthocyanidins
Abdpour_2021_Bioorg.Chem_110_104750Chromone derivatives bearing pyridinium moiety as multi-target-directed ligands against Alzheimer's disease
Abdulkadir_2021_J.Alzheimers.Dis__Taurine and Camel Milk Modulate Neurobehavioral and Biochemical Changes in Aluminum Chloride-Induced Alzheimer's Disease in Rats
Abdulrahim_2021_J.Cannabis.Res_3_38Cannabis sativa and/or melatonin do not alter brain lipid but alter oxidative mechanisms in female rats
Aboelhadid_2021_PLoS.One_16_e0260172Acaricidal activity of Foeniculum vulgare against Rhipicephalus annulatus is mainly dependent on its constituent from trans-anethone
Abokitse_2021_Appl.Environ.Microbiol__A Novel Actinobacterial Cutinase Containing a Non-Catalytic Polymer-Binding Domain
Abol-Fotouh_2021_Int.J.Biol.Macromol_181_125Optimization, purification, and biochemical characterization of thermoalkaliphilic lipase from a novel Geobacillus stearothermophilus FMR12 for detergent formulations
Abolins_2021_Materials.(Basel)_14_Impact of Different Epoxidation Approaches of Tall Oil Fatty Acids on Rigid Polyurethane Foam Thermal Insulation
Aboubakr_2021_Pharmaceuticals.(Basel)_14_Antioxidant and Anti-Inflammatory Potential of Thymoquinone and Lycopene Mitigate the Chlorpyrifos-Induced Toxic Neuropathy
Abrami_2021_Nat.Chem.Biol_17_438Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
Abu-Taweel_2021_J.Trace.Elem.Med.Biol_68_126842Pomegranate juice moderates anxiety- and depression-like behaviors in AlCl(3)-treated male mice
Ackerman_2021_Nature__Astrocytes close a motor circuit critical period
Adaixo_2021_Biorxiv__Cryo-EM structure of native human thyroglobulin
Adebayo_2021_Drug.Metab.Pers.Ther__Cnidoscolus aconitifolius-supplemented diet enhanced neurocognition, endogenous antioxidants and cholinergic system and maintains hippocampal neuronal integrity in male Wistar rats
Adebayo_2021_Drug.Metab.Pers.Ther__2Long-term consumption of Moringa oleifera-supplemented diet enhanced neurocognition, suppressed oxidative stress, acetylcholinesterase activity and neuronal degeneration in rat's hippocampus
Adedara_2021_Environ.Sci.Pollut.Res.Int__Chronic ciprofloxacin and atrazine co-exposure aggravates locomotor and exploratory deficits in non-target detritivore speckled cockroach (Nauphoeta cinerea)
Adeel_2021_Int.J.Pharm__121374A Carrier Free Delivery System of a Monoacylglycerol Lipase Hydrophobic Inhibitor
Adeel_2021_J.Hazard.Mater_415_125574Bio-interaction of nano and bulk lanthanum and ytterbium oxides in soil system: Biochemical, genetic, and histopathological effects on Eisenia fetida
Adefegha_2021_Andrologia__e14074Berberine modulates crucial erectogenic biomolecules and alters histological architecture in penile tissues of diabetic rats
Adefegha_2021_J.Basic.Clin.Physiol.Pharmacol__Effects of berberine on cholinesterases and monoamine oxidase activities, and antioxidant status in the brain of streptozotocin (STZ)-induced diabetic rats
Adefegha_2021_J.Complement.Integr.Med__Comparative effects of berberine and piperine on the neuroprotective potential of neostigmine
Adefegha_2021_Metab.Brain.Dis__Moringa oleifera modulates cholinergic and purinergic enzymes activity in BV-2 microglial cells
Adefegha_2021_Toxicol.Res_37_249beta-caryophyllene improves sexual performance via modulation of crucial enzymes relevant to erectile dysfunction in rats
Adeowo_2021_Chem.Biodivers__Tailored Modeling of Rivastigmine Derivatives as Dual Acetylcholinesterase and Butyrylcholinesterase Inhibitors for Alzheimer's Disease Treatment
Adetunji_2021_Braz.J.Microbiol__Production strategies and biotechnological relevance of microbial lipases: a review
Adewole_2021_In.Silico.Pharmacol_9_14BACE1 and cholinesterase inhibitory activities of compounds from Cajanus cajan and Citrus reticulata: an in silico study
Adhikari_2021_Toxicol.Rep_8_1883Gradual reduction of susceptibility and enhanced detoxifying enzyme activities of laboratory-reared Aedes aegypti under exposure of temephos for 28 generations
Adib_2021_Saudi.J.Biol.Sci_28_3893Cholinesterase inhibitory activity of tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia: In vitro and in silico studies targeting management of Alzheimer's disease
Adina_2021_J.Genet.Eng.Biotechnol_19_55Expression of novel acidic lipase from Micrococcus luteus in Pichia pastoris and its application in transesterification
Adole_2021_Anal.Biochem__114158Clinical utility of validated gas chromatography-ion trap mass spectrometry in patients with anticholinesterase pesticides poisoning
Afsa_2021_Environ.Sci.Pollut.Res.Int__A multi-biomarker approach for the early assessment of the toxicity of hospital wastewater using the freshwater organism Daphnia magna
Afzal_2021_Molecules_26_Analgesic and Anticancer Activity of Benzoxazole Clubbed 2-Pyrrolidinones as Novel Inhibitors of Monoacylglycerol Lipase
Afzali_2021_Drug.Res.(Stuttg)_71_10Investigating the Effect of Fresh Frozen Plasma and Albumin on DNA Damage and Oxidative Stress Biomarkers in Poisoning Cases by Organophosphates
Agami_2021_Anal.Bioanal.Chem__LC-MS bioanalysis of targeted nasal galantamine bound chitosan nanoparticles in rats' brain homogenate and plasma
Agostini_2021_Neurosci_455_251Gallic Acid Reverses Neurochemical Changes Induced by Prolonged Ethanol Exposure in the Zebrafish Brain
Agrawal_2021_Bioresour.Technol_339_125603Economizing the lignocellulosic hydrolysis process using heterologously expressed auxiliary enzymes feruloyl esterase D (CE1) and beta-xylosidase (GH43) derived from thermophilic fungi Scytalidium thermophilum
Aguera-Ortiz_2021_Front.Psychiatry_12_638651Depression in Alzheimer's Disease: A Delphi Consensus on Etiology, Risk Factors, and Clinical Management
Aguirre-Rojas_2021_Sci.Rep_11_11448Comparative analyses of transcriptional responses of Dectes texanus LeConte (Coleoptera: Cerambycidae) larvae fed on three different host plants and artificial diet
Agwa_2021_Cells_10_ABHD4-Regulating RNA Panel: Novel Biomarkers in Acute Coronary Syndrome Diagnosis
Ahammed_2021_Adv.Pharmacol.Pharm.Sci_2021_5569054Acetylcholinesterase Inhibitory and Antioxidant Activity of the Compounds Isolated from Vanda roxburghii
Ahmad_2021_Biorxiv__Substrate access mechanism in a novel membrane-bound 1 phospholipase A of Pseudomonas aeruginosa concordant with specificity and regioselectivity
Ahmad_2021_Curr.Neuropharmacol__Study of Nutraceuticals and Phytochemicals for the Management of Alzheimer's Disease: A Review
Ahmad_2021_Curr.Opin.Infect.Dis_34_187Bacterial RTX toxins and host immunity
Ahmad_2021_Molecules_26_Biocomputational Screening of Natural Compounds against Acetylcholinesterase
Ahmad_2021_Saudi.J.Biol.Sci_28_6352Evaluation of analgesic, antiamnesic and antidiarrheal potentials of Medicago denticulata extract using animal model
Ahmaditabatabaei_2021_J.Fungi.(Basel)_7_Fungal Enzymes as Catalytic Tools for Polyethylene Terephthalate (PET) Degradation
Ahmed_2021_Biomed.Pharmacother_139_111609Potential therapeutic natural products against Alzheimer's disease with Reference of Acetylcholinesterase
Ahmed_2021_Environ.Sci.Pollut.Res.Int_28_2146Premna odorata extract as a protective agent on neurotoxic effect of aluminum: neurochemical, molecular, and histopathological alterations
Ahmed_2021_J.Biomol.Struct.Dyn__1Computational and SAXS-based structure insights of pectin acetyl esterase (CtPae12B) of family 12 carbohydrate esterase from Clostridium thermocellum ATCC 27405
Ahmed_2021_J.Venom.Anim.Toxins.Incl.Trop.Dis_27_e20200047Kinetic and toxicological effects of synthesized palladium(II) complex on snake venom (Bungarus sindanus) acetylcholinesterase
Ahsan_2021_Inflammopharmacology__Pharmacological support to anti-arthritic prospective of physostigmine: a new approach
Ahsan_2021_J.Basic.Microbiol__Enzyme-assisted bioremediation approach for synthetic dyes and polycyclic aromatic hydrocarbons degradation
Ahuja-Casarin_2021_J.Enzyme.Inhib.Med.Chem_36_138Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
Aissa_2021_Bioorg.Med.Chem.Lett__128000Fiaud's Acid, a novel organocatalyst for diastereoselective bis alpha-aminophosphonates synthesis with in-vitro biological evaluation of antifungal, antioxidant and enzymes inhibition potential
Ajayi_2021_Metabol.Open_9_100077High-fat diet-induced memory impairment and anxiety-like behavior in rats attenuated by peel extract of Ananas comosus fruit via atheroprotective, antioxidant and anti-inflammatory actions
Ajima_2021_Environ.Sci.Pollut.Res.Int__Sublethal diclofenac induced oxidative stress, neurotoxicity, molecular responses and alters energy metabolism proteins in Nile tilapia, Oreochromis niloticus
Ak_2021_Food.Chem.Toxicol_153_112268Tanacetum vulgare L. (Tansy) as an effective bioresource with promising pharmacological effects from natural arsenal
Akaberi_2021_Phytochemistry_191_112923Phytochemistry and pharmacology of alkaloids from Glaucium spp
Akbar_2021_J.Food.Biochem__e13936Neuroprotective potential of berberine in modulating Alzheimer's disease via multiple signaling pathways
Akdag_2021_Biotechnol.Appl.Biochem_68_1113Conducting polymer-based electrochemical biosensor for the detection of acetylthiocholine and pesticide via acetylcholinesterase
Akhtar_2021_Psychopharmacology.(Berl)__7,8-Dihydroxyflavone improves cognitive functions in ICV-STZ rat model of sporadic Alzheimer's disease by reversing oxidative stress, mitochondrial dysfunction, and insulin resistance
Akincioglu_2021_Comput.Biol.Chem_94_107565Cholinesterases, carbonic anhydrase inhibitory properties and in silico studies of novel substituted benzylamines derived from dihydrochalcones
Akintunde_2021_Biochem.Biophys.Rep_26_100999Biogenic zinc-oxide nanoparticles of Moringa oleifera leaves abrogates rotenone induced neuroendocrine toxicity by regulation of oxidative stress and acetylcholinesterase activity
Akkol_2021_Curr.Neuropharmacol__Effects of Natural Products on Neuromuscular Junction
Akocak_2021_Chem.Biodivers__Synthesis, characterization, and inhibition study of novel substituted phenylureido sulfaguanidine derivatives as alpha-glycosidase and cholinesterase inhibitors
Akomolafe_2021_J.Food.Biochem__e13629Diets supplemented with raw and roasted pumpkin (Cucurbita pepo L) seeds improved some biochemical parameters associated with erectile function in rats
Akpa_2021_Toxicol.Res_37_163Protective effect of fisetin against subchronic chlorpyrifos-induced toxicity on oxidative stress biomarkers and neurobehavioral parameters in adult male albino mice
Al Hamoui Dit Banni_2021_Analyst_146_1386Screening for pancreatic lipase natural modulators by capillary electrophoresis hyphenated to spectrophotometric and conductometric dual detection
Al Mughairbi_2021_Saudi.Pharm.J_29_1043Neuroprotective effects of Bhilawanol and Anacardic acid during glutamate-induced neurotoxicity
Al-Aqaba_2021_Br.J.Ophthalmol_105_285In vivo confocal microscopy features and clinicohistological correlation of limbal nerve corpuscles
Al-Brakati_2021_Neurotox.Res_39_198Possible Role of Kaempferol in Reversing Oxidative Damage, Inflammation, and Apoptosis-Mediated Cortical Injury Following Cadmium Exposure
Al-Emam_2021_Toxicol.Rep_8_1226Butyryl-cholinesterase deficiency: A case report of delayed recovery after general anaesthesia
Al-Hamed_2021_Alzheimers.Dement.(N.Y)_7_e12184Acetylcholinesterase inhibitors and risk of bleeding and acute ischemic events in non-hypertensive Alzheimer's patients
Al-Hazmi_2021_Metab.Brain.Dis__Biochemical, histological, and neuro-physiological effects of long-term aluminum chloride exposure in rats
Al-Kuraishy_2021_Front.Cardiovasc.Med_8_644095COVID-19 in Relation to Hyperglycemia and Diabetes Mellitus
Al-Samawi_2021_Indian.Heart.J__Association of the lipoprotein lipase and Apolipoprotein C-II gene polymorphisms with risk of dyslipidemia in smokers and non-smokers male
Al-Serri_2021_Saudi.J.Biol.Sci_28_4717Association between the lipoprotein lipase rs1534649 gene polymorphism in intron one with Body Mass Index and High Density Lipoprotein-Cholesterol
Al-Zaban_2021_Molecules_26_HPLC-Analysis, Biological Activities and Characterization of Action Mode of Saudi Marrubium vulgare against Foodborne Diseases Bacteria
Alabbas_2021_BMC.Pediatr_21_72Wolman's disease presenting with secondary hemophagocytic lymphohistiocytosis: a case report from Saudi Arabia and literature review
Alarcon-Esposito_2021_Curr.Neuropharmacol_19_832From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimer's Disease
Albendin_2021_Int.J.Environ.Res.Public.Health_18_Pharmaceutical Products and Pesticides Toxicity Associated with Microplastics (Polyvinyl Chloride) in Artemia salina
Albertini_2021_Med.Res.Rev_41_2606From combinations to multitarget-directed ligands: A continuum in Alzheimer's disease polypharmacology
Alberto-Silva_2021_Toxins.(Basel)_13_Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp Campsomeriella annulata annulata
Albrakati_2021_Int.J.Nanomedicine_16_8447Neuroprotective Efficiency of Prodigiosins Conjugated with Selenium Nanoparticles in Rats Exposed to Chronic Unpredictable Mild Stress is Mediated Through Antioxidative, Anti-Inflammatory, Anti-Apoptotic, and Neuromodulatory Activities
Alejandro_2021_Environ.Monit.Assess_194_23Temporal and spatial analysis of benomyl/carbendazim in water and its possible impact on Nile tilapia (Oreochromis niloticus) from Tenango dam, Puebla, Mexico
Alex_2021_Anal.Chim.Acta_1142_73An ultra-sensitive and selective AChE based colorimetric detection of malathion using silver nanoparticle-graphene oxide (Ag-GO) nanocomposite
Alexander_2021_Proteins__Target highlights in CASP14: Analysis of models by structure providers
Alexandris_2021_Toxicol.Rep_8_73Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions
Alhatali_2021_Clin.Toxicol.(Phila)__1A cluster of tetrodotoxin poisoning in Oman
Alhawarri_2021_Molecules_26_Antioxidant, Anti-Inflammatory, and Inhibition of Acetylcholinesterase Potentials of Cassia timoriensis DC. Flowers
Ali_2021_Exp.Aging.Res__1Behavioral, Biochemical and Histopathological effects of Standardised Pomegranate extract with Vinpocetine, Propolis or Cocoa in a rat model of Parkinson's disease
Ali_2021_Int.Immunopharmacol_96_107729Natural antioxidants enhance the power of physical and mental activities versus risk factors inducing progression of Alzheimer's disease in rats
Ali_2021_Int.J.Biol.Macromol__Sequence and structure-based method to predict diacylglycerol lipases in protein sequence
Ali_2021_Neurochem.Res__Screening of Synthetic Isoxazolone Derivative Role in Alzheimer's Disease: Computational and Pharmacological Approach
Ali_2021_Sci.Total.Environ_780_146590Plastic wastes biodegradation: Mechanisms, challenges and future prospects
Ali_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_263_120180Structure and biomolecular recognition of nitro-BODIPY-andrographolide assembles for cancer treatment
Alikhani_2021_Iran.J.Pharm.Res_20_560Response Surface Study on Molecular Docking Simulations of Citalopram and Donepezil as Potent CNS Drugs
Aliomrani_2021_Neurotoxicol.Teratol__106957-AChR is partly responsible in mice depressive-like behavior after Phosalone exposure
Almadiy_2021_Environ.Sci.Pollut.Res.Int__Bioactivity and safety evaluations of Cupressus sempervirens essential oil, its nanoemulsion and main terpenes against Culex quinquefasciatus Say
Almeida_2021_Environ.Toxicol.Pharmacol__103634Can the insecticide imidacloprid affect the health of the Neotropical freshwater fish Astyanax altiparanae (Teleostei: Characidae)?
Almeida_2021_J.Inorg.Biochem_224_111560Probing the acetylcholinesterase inhibitory activity of a novel Ru(II) polypyridyl complex and the supramolecular interaction by (STD)-NMR
Alonso_2021_Int.J.Biol.Macromol__Discovery of tight-binding competitive inhibitors of dipeptidyl peptidase IV
Alqahtani_2021_Steroids_172_108857Bioactive stigmastadienone from Isodon rugosus as potential anticholinesterase, alpha-glucosidase and COX/LOX inhibitor: In-vitro and molecular docking studies
Alshehri_2021_Biomolecules_11_Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects
Altaf_2021_Hum.Exp.Toxicol__960327121993207Cell membrane enveloped polymeric nanosponge for detoxification of chlorpyrifos poison: In vitro and in vivo studies
Alugubelly_2021_Neurotoxicol__Persistent proteomic changes in glutamatergic and GABAergic signaling in the amygdala of adolescent rats exposed to chlorpyrifos as juveniles
Alves_2021_Bioprocess.Biosyst.Eng_44_57Design for preparation of more active cross-linked enzyme aggregates of Burkholderia cepacia lipase using palm fiber residue
Alves_2021_Braz.J.Biol_81_632The acetylcholinesterase as indicative of intoxication for pesticide in farmers of conventional and organic cultivation
Alvi_2021_Oxid.Med.Cell.Longev_2021_9966663Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway
Aly_2021_IBRO.Neurosci.Rep_10_109Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: A systematic review
Alzweiri_2021_Bioorg.Med.Chem.Lett__128205The structural simplification of lysergic acid as a natural lead for synthesizing novel anti-Alzheimer agents
Amala_2021_Molecules_26_Bioefficacy of Epaltes divaricata (L.) n-Hexane Extracts and Their Major Metabolites against the Lepidopteran Pests Spodoptera litura (fab.) and Dengue Mosquito Aedes aegypti (Linn.)
Aman_2021_Crit.Care.Clin_37_673Management of Organophosphorus Poisoning: Standard Treatment and Beyond
Amat-Ur-Rasool_2021_Brain.Sci_11_Anti-Cholinesterase Combination Drug Therapy as a Potential Treatment for Alzheimer's Disease
Amat-Ur-Rasool_2021_Curr.Issues.Mol.Biol_44_152In Silico Design of Dual-Binding Site Anti-Cholinesterase Phytochemical Heterodimers as Treatment Options for Alzheimer's Disease
Amezian_2021_Insect.Biochem.Mol.Biol_138_103646Comparative analysis of the detoxification gene inventory of four major Spodoptera pest species in response to xenobiotics
Amin_2021_Bioorg.Chem_110_104792Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's disease
Amin_2021_Biotechnol.Appl.Biochem__Penicillium fellutanum lipase as a green and ecofriendly biocatalyst for depolymerization of poly (sigma-caprolactone): Biochemical, kinetic, and thermodynamic investigations
Amin_2021_Environ.Technol__1Cholinesterase activity as a potential biomarker for neurotoxicity induced by pesticides in vivo exposed Oreochromis niloticus (Nile tilapia)
Amin_2021_Front.Physiol_12_628107Melatonin-Pretreated Mesenchymal Stem Cells Improved Cognition in a Diabetic Murine Model
Amirahmadi_2021_Metab.Brain.Dis__Folic acid attenuated learning and memory impairment via inhibition of oxidative damage and acetylcholinesterase activity in hypothyroid rats
Amitai_2021_Commun.Biol_4_573Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase
An_2021_J.Clin.Pharmacol_61_531Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors
Anantayanon_2021_Gene__145745Significance of two intracellular triacylglycerol lipases of Aspergillus oryzae in lipid mobilization: A perspective in industrial implication for microbial lipid production
Anastassiadou_2021_EFSA.J_19_e06392Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides
Andersson_2021_Methods.Mol.Biol_2309_245Structural Analysis of Strigolactone-Related Gene Products
Andrejcakova_2021_Saudi.J.Biol.Sci_28_3789Dietary flaxseed's protective effects on body tissues of mice after oral exposure to xylene
Andrys_2021_Mol.Pharm__Effect of Oxime Encapsulation on Acetylcholinesterase Reactivation: Pharmacokinetic Study of the Asoxime-Cucurbit[7]uril Complex in Mice Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry
Angeloni_2021_Plants.(Basel)_10_Phytochemical Profile and Biological Activities of Crude and Purified Leonurus cardiaca Extracts
Anglister_2021_J.Neurochem__Preface: Cholinergic mechanisms: This is the Preface for the special issue Cholinergic Mechanisms
Angrand_2021_Toxicology__152787Persistent brainwave disruption and cognitive impairment induced by acute sarin surrogate sub-lethal dose exposure
Anita_2021_Psychoneuroendocrinology_126_105149Serum soluble epoxide hydrolase related oxylipins and major depression in patients with type 2 diabetes
Anjireddy_2021_Mini.Rev.Med.Chem__A new mode of Thinfilm and Nanofiber for burst release of the drug for Alzheimer disease; A complete scenario from dispersible polymer to formulation methodology
Anjos_2021_Rev.Paul.Pediatr_39_e2019262SEVERE ACUTE TOXIC EXPOSURES IN CHILDREN AND ADOLESCENTS: CASE SERIES
Annac_2021_J.Food.Biochem__e13881The protective effects of pomegranate juice on lead acetate-induced neurotoxicity in the male rat: A histomorphometric and biochemical study
Ansari_2021_Arch.Pharm.(Weinheim)__e2100376Biology-oriented drug synthesis and evaluation of secnidazole esters as novel enzyme inhibitors
Antoniolli_2021_Curr.Med.Chem_28_4259Chalcones Acting as Inhibitors of Cholinesterases, beta-Secretase and beta- Amyloid Aggregation and other Targets for Alzheimer's Disease: A Critical Review
Anukanon_2021_ACS.Omega_6_19924In Silico-Guided Rational Drug Design and Semi-synthesis of C(2)-Functionalized Huperzine A Derivatives as Acetylcholinesterase Inhibitors
Anupama_2021_J.Biomol.Struct.Dyn__1Jatamansinol from Nardostachys jatamansi: a multi-targeted neuroprotective agent for Alzheimer's disease
Anwar_2021_Antioxidants.(Basel)_10_A Leaf Extract of Harrisonia abyssinica Ameliorates Neurobehavioral, Histological and Biochemical Changes in the Hippocampus of Rats with Aluminum Chloride-Induced Alzheimer's Disease
Arafa_2021_Vet.Parasitol_290_109346Control of Rhipicephalus annulatus resistant to deltamethrin by spraying infested cattle with synergistic eucalyptus essential oil-thymol-deltamethrin combination
Aramjoo_2021_Environ.Sci.Pollut.Res.Int__Modulatory effect of opioid administration on the activity of cholinesterase enzyme: a systematic review of mice/rat models
Araujo_2021_ACS.Med.Chem.Lett_12_548Glucosamine and Its Analogues as Modulators of Amyloid-beta Toxicity
Araujo_2021_Environ.Sci.Pollut.Res.Int__Effects of exposure to the UV-filter 4-MBC during Solea senegalensis metamorphosis
Arellano-Saab_2021_Proc.Natl.Acad.Sci.U.S.A_118_Three mutations repurpose a plant karrikin receptor to a strigolactone receptor
Aresti-Sanz_2021_Pharmaceuticals.(Basel)_14_Stability of Methylphenidate under Various pH Conditions in the Presence or Absence of Gut Microbiota
Arora_2021_Ecotoxicol.Environ.Saf_226_112790Mixture toxicity assessment of selected insecticides to silver perch fingerling, Bidyanus bidyanus
Arranz San Martin_2022_Biomolecules_12_170Enzyme-Mediated Quenching of the Pseudomonas Quinolone Signal (PQS): A Comparison between Naturally Occurring and Engineered PQS-Cleaving Dioxygenases
Arshad_2021_Biomolecules_11_RP-UHPLC-MS Chemical Profiling, Biological and In Silico Docking Studies to Unravel the Therapeutic Potential of Heliotropium crispum Desf. as a Novel Source of Neuroprotective Bioactive Compounds
Arya_2021_Biomolecules_11_Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer's Disease Therapy
Arya_2021_Front.Plant.Sci_12_663165The Plant Cuticle: An Ancient Guardian Barrier Set Against Long-Standing Rivals
Arya_2021_Plant.Physiol.Biochem_161_234Brassica juncea leaf cuticle proteome analysis shows myrosinase protein, antifreeze activity, and post-translationally modified secretory proteins
Asada_2021_Biochem.Biophys.Res.Commun_549_105Secretory production of a camelid single-domain antibody (VHH, nanobody) by the Serratia marcescens Lip system in Escherichia coli
Ashok_2021_Bioorg.Med.Chem.Lett__128212Design, synthesis and biological evaluation of novel deoxyvasicinone-indole as multi-target agents for Alzheimer's disease
Askin_2021_Bioorg.Chem_113_105009Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors
Aslam_2021_Biomed.Res.Int_2021_6631042Anti-5'-Nucleotidases (5'-ND) and Acetylcholinesterase (AChE) Activities of Medicinal Plants to Combat Echis carinatus Venom-Induced Toxicities
Atalar_2021_J.Food.Biochem__e13975The effects of Daucus carota extract against PC3, PNT1a prostate cells, acetylcholinesterase, glutathione S-transferase, and alpha-glycosidase; an in vitro-in silico study
Atamanalp_2021_Toxicol.Mech.Methods__1Treatment of Oxidative Stress, Apoptosis, and DNA Injury with N-acetylcysteine at simulative pesticide toxicity in fish
Atanasova_2021_Int.J.Mol.Sci_22_Plastic Degradation by Extremophilic Bacteria
Ateba_2021_Front.Pharmacol_12_641225The Genus Eriosema (Fabaceae): From the Ethnopharmacology to an Evidence-Based Phytotherapeutic Perspective?
Ates_2021_Z.Naturforsch.C.J.Biosci__New indane derivatives containing 2-hydrazinothiazole as potential acetylcholinesterase and monoamine oxidase-B inhibitors
Athar_2021_Mol.Biol.Rep__Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease
Atrahimovich_2021_Metabolites_11_Galantamine Quantity and Alkaloid Profile in the Bulbs of Narcissus tazetta and daffodil cultivars (Amaryllidaceae) Grown in Israel
Attademo_2021_Environ.Sci.Pollut.Res.Int__Effects of the emulsifiable herbicide Dicamba on amphibian tadpoles: an underestimated toxicity risk?
Attarroshan_2021_Chem.Biodivers__Imino-2H-chromene based derivatives as potential anti-Alzheimer's agents: Design, synthesis, biological evaluation and in silico study
Avolio_2021_Vet.Anim.Sci_13_100178Retrospective data analysis of animal poisoning events in Liguria
Awan_2021_Biochem.Genet__Genetic Association of Butyrylcholinesterase with Major Depressive Disorder
Aydin_2021_Arch.Pharm.(Weinheim)__e2000330Synthesis of N-alkylated pyrazolo[3,4-d]pyrimidine analogs and evaluation of acetylcholinesterase and carbonic anhydrase inhibition properties
Aydin_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_267_120501A reaction-based system for the colorimetric detection of glyphosate in real samples
Azadniya_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1184_122956High-throughput enzyme inhibition screening of 44 Iranian medicinal plants via piezoelectric spraying of planar cholinesterase assays
Azevedo_2021_Chemosphere_263_128029Effects of pyriproxyfen on zebrafish brain mitochondria and acetylcholinesterase
Azevedo_2021_Front.Bioeng.Biotechnol_9_805059In Silico Evaluation of Enzymatic Tunnels in the Biotransformation of alpha-Tocopherol Esters
Baakman_2021_Br.J.Clin.Pharmacol__Acute response to cholinergic challenge predicts long-term response to galantamine treatment in patients with Alzheimer's Disease
Baath_2021_Biotechnol.Bioeng__Structure-function analysis of two closely related cutinases from Thermobifida cellulosilytica
Babaee_2021_Chem.Biodivers__Design, synthesis, and molecular docking of some novel tacrine based cyclopentapyranopyridin- and tetrahydropyranoquinolin-kojic acid derivatives as anti-acetylcholinesterase agents
Babic_2021_J.Alzheimers.Dis_82_661The Association of Essential Metals with APOE Genotype in Alzheimer's Disease
Babin_2021_ACS.Cent.Sci_7_803Chemiluminescent Protease Probe for Rapid, Sensitive, and Inexpensive Detection of Live Mycobacterium tuberculosis
Bacchetti_2021_Eur.J.Clin.Invest_51_e13452Paraoxonase-2: A potential biomarker for skin cancer aggressiveness
Bacha_2021_Int.J.Phytoremediation__1Protective effect of the Spirulina platensis against toxicity induced by Diuron exposure in Mytilus galloprovincialis
Bachurin_2021_Molecules_26_Conjugation of Aminoadamantane and gamma-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands
Badalamenti_2021_J.Ethnopharmacol__114050The ethnobotany, phytochemistry and biological properties of genus Ferulago - A review
Badino_2021_Enzyme.Microb.Technol_152_109937Adsorption of enzymes with hydrolytic activity on polyethylene terephthalate
Badjic_2021_Chemistry__Molecular Recognition of Nerve Agents and Their Organophosphorus Surrogates: Toward Supramolecular Scavengers and Catalysts
Badshah_2021_Molecules_26_Isolation, Characterization, and Medicinal Potential of Polysaccharides of Morchella esculenta
Badwal_2021_J.Geriatr.Psychiatry.Neurol__891988720988916Psychosis Management in Lewy Body Dementia: A Comprehensive Clinical Approach
Bae_2021_Int.J.Syst.Evol.Microbiol__Ferrimonas lipolytica sp. nov., a facultatively anaerobic bacterium isolated from seawater
Bahloul_2021_Acute.Crit.Care__Clinical characteristics and outcomes of critically ill COVID-19 patients in Sfax, Tunisia
Bai_2021_Environ.Microbiol__Ric8 acts as a regulator of G-protein signaling required for nematode-trapping lifecycle of Arthrobotrys oligospora
Bai_2021_Pest.Manag.Sci_77_2129Enhanced hydrolysis of beta-cypermethrin caused by deletions in the glycin-rich region of carboxylesterase 001G from Helicoverpa armigera
Baine_2021_J.Cell.Mol.Med__Pyridostigmine improves cardiac function and rhythmicity through RyR2 stabilization and inhibition of STIM1-mediated calcium entry in heart failure
Bajad_2021_Future.Med.Chem__A systematic review of carbohydrate-based bioactive molecules for Alzheimer's disease
Bajaj_2021_Brain.Res.Bull__The role of endocannabinoid pathway in the neuropathology of Alzheimer's disease: Can the inhibitors of MAGL and FAAH prove to be potential therapeutic targets against the cognitive impairment associated with Alzheimer's disease?
Bajaj_2021_J.Assoc.Physicians.India_69_25Clinical Evidence of Evogliptin plus Metformin in Management of Type 2 Diabetes mellitus
Bakare_2021_BMC.Mol.Cell.Biol_22_49Evaluation of selected carotenoids of Lycopersicon esculentum variants as therapeutic targets for 'Alzheimer's disease: an in silico approach
Bakker_2021_Drugs.R.D__Safety and Pharmacokinetics of HTL0018318, a Novel M(1) Receptor Agonist, Given in Combination with Donepezil at Steady State: A Randomized Trial in Healthy Elderly Subjects
Bakkes_2021_Front.Microbiol_12_750150Biosensor-Based Optimization of Cutinase Secretion by Corynebacterium glutamicum
Bal_2021_Arch.Pharm.(Weinheim)__e2000422Synthesis, characterization, crystal structure, alpha-glycosidase, and acetylcholinesterase inhibitory properties of 1,3-disubstituted benzimidazolium salts
Balaei-Kahnamoei_2021_Evid.Based.Complement.Alternat.Med_2021_5965061Phytochemical Analysis and Evaluation of Biological Activity of Lawsonia inermis Seeds Related to Alzheimer's Disease
Balasch_2021_Mar.Pollut.Bull_172_112918Short-term exposure to polymethylmethacrylate nanoplastics alters muscle antioxidant response, development and growth in Sparus aurata
Balazs_2021_Geroscience__Cholinesterase inhibitors for the treatment of dementia: real-life data in Hungary
Balazs_2021_Ideggyogy.Sz_74_379Cholinesterase inhibitors and memantine for the treatment of Alzheimer and non-Alzheimer dementias
Baldini_2021_Mol.Biol.Evol__Phylogenetic and molecular analyses identify SNORD116 targets involved in the Prader Willi syndrome
Baldinotti_2021_Eur.J.Pharmacol__174499Protective effects of octylseleno-xylofuranoside in a streptozotocin-induced mouse model of Alzheimer's disease
Baloch_2021_Curr.Microbiol__The Occurrence of Triple Catalytic Characteristics of Yeast Lipases and Their Application Prospects in Biodiesel Production from Non-Edible Jatropha curcas Oil in a Solvent-Free System
Bandoni_2021_Sci.Rep_11_9563Cholinergic stimulation with pyridostigmine modulates a heart-spleen axis after acute myocardial infarction in spontaneous hypertensive rats
Banji_2021_Biomed.Res.Int_2021_6645720Neuroprotective Effect of Turmeric Extract in Combination with Its Essential Oil and Enhanced Brain Bioavailability in an Animal Model
Banna_2021_Biol.Trace.Elem.Res__Parental Lead Exposure Promotes Neurobehavioral Disorders and Hepatic Dysfunction in Mouse Offspring
Banno_2021_Nephrol.Ther__Risk factors for peritoneal dialysis withdrawal due to peritoneal dialysis-related peritonitis
Bansal_2021_Climacteric__1Selective ER-beta agonists alleviate neuronal deficits in insulin-resistant estrogen-deficient rats
Bansal_2021_Plant.Cell.Rep__Identification and molecular characterization of rice bran-specific lipases
Bao_2021_ChemMedChem__Design, Synthesis, and Structure-Activity Relationship Study of Pyrazolones as Potent Inhibitors against Pancreatic Lipase
Baranowska-Kortylewicz_2021_J.Pediatr.Hematol.Oncol__Multifarious Functions of Butyrylcholinesterase in Neuroblastoma: Impact of BCHE Deletion on the Neuroblastoma Growth In Vitro and In Vivo
Barbeche_2021_Curr.Top.Med.Chem__Chemical composition, acetylcholine esterase and Anti-bacterial activities of essential oils of Elaeosilenum thapsioides (Desf.) Maire from Algeria
Bardaweel_2021_Acta.Pharm_71_175Sitagliptin: a potential drug for the treatment of COVID-19?
Bargiel_2021_Medicina.(Kaunas)_57_Recognized and Potentially New Biomarkers-Their Role in Diagnosis and Prognosis of Cardiovascular Disease
Barman_2021_Phytother.Res__Nutmegs and wild nutmegs: An update on ethnomedicines, phytochemicals, pharmacology, and toxicity of the Myristicaceae species
Barmpa_2021_J.Inorg.Biochem_217_111357Copper(II) complexes with meclofenamate ligands: Structure, interaction with DNA and albumins, antioxidant and anticholinergic activity
Barmpa_2021_J.Inorg.Biochem_222_111507Nickel(II)-meclofenamate complexes: Structure, in vitro and in silico DNA- and albumin-binding studies, antioxidant and anticholinergic activity
Barroso_2021_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_39_100826Transcriptomic and proteomic analysis of the underlying mechanisms of digestion of triacylglycerols and phosphatides and absorption and fate of fatty acids along the midgut of Musca domestica
Bartolone_2021_Front.Aging.Neurosci_13_777819Urinary Incontinence and Alzheimer's Disease: Insights From Patients and Preclinical Models
Baruah_2021_ACS.Pharmacol.Transl.Sci_4_193Sulfonylurea Class of Antidiabetic Drugs Inhibit Acetylcholinesterase Activity: Unexplored Auxiliary Pharmacological Benefit toward Alzheimer's Disease
Baruah_2021_J.Phys.Chem.B__Elevated Fibrinogen Level Reduces Therapeutic Efficiency of AD Drugs: Biophysical Insights into the Interaction of FDA-Approved Cholinesterase Inhibitors with Human Fibrinogen
Barut_2021_Turk.J.Chem_45_1567Pyridine substituted BODIPYs: synthesis, characterization and cholinesterease, alpha-glucosidase inhibitory, DNA hydrolytic cleavage effects
Barzkar_2021_Appl.Biochem.Biotechnol__Marine Bacterial Esterases: Emerging Biocatalysts for Industrial Applications
Bas_2021_J.Food.Biochem__e13769Lead nitrate and cadmium chloride induced hepatotoxicity and nephrotoxicity: Protective effects of sesamol on biochemical indices and pathological changes
Basalan_2021_Arch.Environ.Contam.Toxicol__Effects of Different Ammonia Levels on Tribenuron Methyl Toxicity in Daphnia magna
Basha_2021_Int.J.Biol.Macromol__Deciphering the AChE-binding mechanism with multifunctional tricyclic coumarin anti-Alzheimer's agents using biophysical and bioinformatics approaches and evaluation of their modulating effect on Amyloidogenic peptide assembly
Basit_2021_Drug.Metab.Dispos__Comparison of tissue abundance of non-cytochrome P450 drug metabolizing enzymes by quantitative proteomics between humans and laboratory animal species
Batista_2021_Environ.Pollut_290_118088Importance of exposure route in determining nanosilver impacts on a stream detrital processing chain
Batschauer_2021_Chem.Biol.Interact__109532Behavioral and neurochemical effects in mice after one-generation exposure to low doses of manganese: focus on offspring development
Battle_2021_Cochrane.Database.Syst.Rev_2_CD013306Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta-analysis
Bauernfried_2021_Nat.Struct.Mol.Biol_28_333DPP9 restrains NLRP1 activation
Baussanne_2021_Bioorg.Chem_116_105390Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference
Bautista-Aguilera_2021_Chem.Rec_21_162Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments
Bayle_2021_J.Med.Chem__Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling
Baysal_2021_Molecules_26_Identification of Phenolic Compounds by LC-MS/MS and Evaluation of Bioactive Properties of Two Edible Halophytes: Limonium effusum and L. sinuatum
Bazie_2021_Pathog.Immun_6_1Plasma Extracellular Vesicle Subtypes May be Useful as Potential Biomarkers of Immune Activation in People With HIV
Beato_2021_J.Med.Chem__beta-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer's Disease Therapy
Beddiar_2021_Plants.(Basel)_10_Chemical Composition, Anti-Quorum Sensing, Enzyme Inhibitory, and Antioxidant Properties of Phenolic Extracts of Clinopodium nepeta L. Kuntze
Beg_2021_J.Biol.Chem__100332ATGL activity regulates GLUT1-mediated glucose uptake and lactate production via TXNIP stability in adipocytes
Behairy_2021_Ecotoxicol.Environ.Saf_208_111620Di(2-ethylhexyl) adipate plasticizer triggers hepatic, brain, and cardiac injury in rats: Mitigating effect of Peganum harmala oil
Behera_2021_Phys.Chem.Chem.Phys_23_7302An atomistic view of solvent-free protein liquids: the case of Lipase A
Bektasevic_2021_Chem.Biodivers__Comparative Study of Chemical Composition, Cholinesterase Inhibition and Antioxidant Potential of Mentha pulegium L. Essential Oil
Belinskaia_2021_Int.J.Mol.Sci_22_Esterase Activity of Serum Albumin Studied by (1)H NMR Spectroscopy and Molecular Modelling
Belinskaia_2021_Int.J.Mol.Sci_22_2Serum Albumin in Health and Disease: Esterase, Antioxidant, Transporting and Signaling Properties
Bell_2021_ChemRxiv__Directed Evolution of an Efficient and Thermostable PET Depolymerase
Ben Hassine_2021_Molecules_26_Untargeted Phytochemical Profile, Antioxidant Capacity and Enzyme Inhibitory Activity of Cultivated and Wild Lupin Seeds from Tunisia
Ben Hlima_2021_Mar.Drugs_19_Molecular and Structural Characterizations of Lipases from Chlorella by Functional Genomics
Ben Salah_2021_Bioprocess.Biosyst.Eng__Green Roccella phycopsis Ach. mediated silver nanoparticles: synthesis, characterization, phenolic content, antioxidant, antibacterial and anti-acetylcholinesterase capacities
Ben-Azu_2021_J.Trace.Elem.Med.Biol_71_126919Lead acetate induces hippocampal pyramidal neuron degeneration in mice via up-regulation of executioner caspase-3, oxido-inflammatory stress expression and decreased BDNF and cholinergic activity: Reversal effects of Gingko biloba supplement
Bender_2021_J.Neurol.Surg.A.Cent.Eur.Neurosurg_82_138Early Serum Biomarkers for Intensive Care Unit Treatment within the First 24 Hours in Patients with Intracerebral Hemorrhage
Benfante_2021_Aging.Clin.Exp.Res_33_823Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders
Benham-Pyle_2021_Nat.Cell.Biol_23_939Identification of rare, transient post-mitotic cell states that are induced by injury and required for whole-body regeneration in Schmidtea mediterranea
Benitez_2021_Front.Endocrinol.(Lausanne)_12_636600Nerve Growth Factor: A Dual Activator of Noradrenergic and Cholinergic Systems of the Rat Ovary
Bennion_2021_Sci.Rep_11_15567Development of a CNS-permeable reactivator for nerve agent exposure: an iterative, multi-disciplinary approach
Bentham_2021_Curr.Alzheimer.Res__Cerebrovascular Pathology and Responsiveness to Treatment in Alzheimer's Disease: A Systematic Review
Berenstein_2021_Chemosphere_290_133221Environmental fate of dibutylphthalate in agricultural plastics: Photodegradation, migration and ecotoxicological impact on soil
Bergamaschi_2021_Clin.Exp.Med__1Anemia in patients with Covid-19: pathogenesis and clinical significance
Bergmann_2021_Sci.Rep_11_16555TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function
Bernabeu-Roda_2021_Methods.Mol.Biol_2309_91Analyzing the Effect of Strigolactones on the Motility Behavior of Rhizobia
Berselli_2021_Chembiochem_22_2032Novel Pet-Degrading Enzymes: Structure-Function from a Computational Perspective
Bertolini_2021_Front.Chem_9_771612Unveiling the Enzymatic Degradation Process of Biobased Thiophene Polyesters
Beselia_2021_Neuroreport__Modulation of prefrontal cortex function by basal forebrain cholinergic and GABAergic neurons at the behavioral and molecular level
Beversdorf_2021_Cogn.Behav.Neurol_34_182The Effect of Donepezil on Problem-solving Ability in Individuals With Amnestic Mild Cognitive Impairment: A Pilot Study
Bezerra_2021_Bioorg.Med.Chem_44_116299Larvicidal activity and in silico studies of cinnamic acid derivatives against Aedes aegypti (Diptera: Culicidae)
Bezerra_2021_Clin.Nutr__Do implant-supported prostheses affect bioavailability of nutrients of complete and partially edentulous patients? A systematic review with meta-analysis
Bhanderi_2021_Materials.(Basel)_14_Optimized Rivastigmine Nanoparticles Coated with Eudragit for Intranasal Application to Brain Delivery: Evaluation and Nasal Ciliotoxicity Studies
Bhardwaj_2021_3.Biotech_11_308Purification of high molecular weight thermotolerant esterase from Serratia sp. and its characterization
Bhardwaj_2021_Drug.Chem.Toxicol__1Analysis of suppressive effects of pesticide triazophos on leucocyte immune responses in a teleost, Channa Punctatus
Bhatia_2021_Curr.Alzheimer.Res_18_802Multi-Target Directed Ligands (MTDLs): Promising Coumarin Hybrids for Alzheimer's Disease
Bhatia_2021_Physiol.Behav_241_113592Thromboxane A2 synthase inhibition ameliorates endothelial dysfunction, memory deficits, oxidative stress and neuroinflammation in rat model of streptozotocin diabetes induced dementia
Bhattacharyya_2021_Environ.Microbiol.Rep__Phthalate hydrolase: distribution, diversity and molecular evolution
Bhattrai_2021_J.Nepal.Health.Res.Counc_19_498Health Impact Associated with Pesticides Use among Vegetables Farmers in Nepal: A Secondary Analysis
Bhavya_2021_J.Food.Sci.Technol_58_1611Efficacy of Ocimum tenuiflorum essential oil as grain protectant against coleopteran beetle, infesting stored pulses
Bhunia_2021_Plant.Mol.Biol_105_247Functional characterization of two type-1 diacylglycerol acyltransferase (DGAT1) genes from rice (Oryza sativa) embryo restoring the triacylglycerol accumulation in yeast
Bi_2021_Pathol.Oncol.Res_27_580800Cholinesterase is Associated With Prognosis and Response to Chemotherapy in Advanced Gastric Cancer
Bi_2021_Turk.J.Chem_45_805Novel Mannich bases with strong carbonic anhydrases and acetylcholinesterase inhibition effects: 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2(3H)-benzoxazolones
Biberoglu_2021_J.Turkish.chem.soc.sect.chem_8_435Kinetics of human butyrylcholinesterase inhibition by 1,9-dimethyl-methylene blue
Bicca_2021_Environ.Sci.Pollut.Res.Int__A subchronic low-dose exposure of a glyphosate-based herbicide induces depressive and anxious-like behavior in mice: quercetin therapeutic approach
Biermann_2021_Angew.Chem.Int.Ed.Engl__Fatty Acids and their Derivatives as Renewable Platform Molecules for the Chemical Industry
Bigley_2021_Biochemistry__Substrate Analogues for the Enzyme-Catalyzed Detoxification of the Organophosphate Nerve Agents-Sarin, Soman, and Cyclosarin
Bilal_2021_Bioelectrochemistry_144_107999Assessment of pesticide induced inhibition of Apis mellifera (honeybee) acetylcholinesterase by means of N-doped carbon dots/BSA nanocomposite modified electrochemical biosensor
Bilal_2021_Food.Chem_346_128894An insect acetylcholinesterase biosensor utilizing WO(3)/g-C(3)N(4) nanocomposite modified pencil graphite electrode for phosmet detection in stored grains
Bilal_2021_Int.J.Biol.Macromol__Immobilized lipases-based nano-biocatalytic systems - A versatile platform with incredible biotechnological potential
Bilska_2021_PLoS.One_16_e0260030Effect of Morus alba leaf extract dose on lipid oxidation, microbiological stability, and sensory evaluation of functional liver pts during refrigerated storage
Bingol_2021_Heliyon_7_e06986Antidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) - profiling of phenolic compounds by LC-HRMS
Birdane_2021_Environ.Sci.Pollut.Res.Int__The protective effects of erdosteine on subacute diazinon-induced oxidative stress and inflammation in rats
Birsan_2021_Foods_10_Anticholinesterase Activities of Different Solvent Extracts of Brewer's Spent Grain
Bisht_2021_Trop.Anim.Health.Prod_53_460Comparative susceptibility of Rhipicephalus microplus collected from the northern state of India to coumaphos, malathion, deltamethrin, ivermectin, and fipronil
Bist_2021_Sci.Rep_11_3668Defensive proclivity of bacoside A and bromelain against oxidative stress and AChE gene expression induced by dichlorvos in the brain of Mus musculus
Biswas_2021_Drug.Chem.Toxicol__1Non-permitted food colorants induced neurotoxicity in cerebellum of rat brain
Bjedov_2021_Animals.(Basel)_11_Application of Non-Destructive Methods: Biomarker Assays in Blood of White Stork (Ciconia ciconia) Nestlings
Bjorkgren_2021_Front.Cell.Dev.Biol_9_710864Alpha/Beta Hydrolase Domain-Containing Protein 2 regulates the rhythm of follicular maturation and estrous stages of the female reproductive cycle
Blanco-Ania_2021_Methods.Mol.Biol_2309_37Synthesis of Analogs of Strigolactones and Evaluation of Their Stability in Solution
Blankers_2021_R.Soc.Open.Sci_8_210180Sex pheromone signal and stability covary with fitness
Blazquez-Sanchez_2021_Appl.Environ.Microbiol__AEM0184221Antarctic polyester hydrolases degrade aliphatic and aromatic polyesters at moderate temperatures
Bleffert_2021_Biorxiv__Evidence for a bacterial Lands cycle phospholipase A: Structural and mechanistic insights into membrane phospholipid remodeling
Bloch_2021_Shock_55_796Hyper-Activation of Endogenous GLP-1 System to Gram-negative Sepsis Is Associated With Early Innate Immune Response and Modulated by Diabetes
Blumenthal_2021_J.Biol.Chem__Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects
Boes_2021_Membranes.(Basel)_11_Peripheral Membrane Proteins: Promising Therapeutic Targets across Domains of Life
Boga_2021_J.Ethnopharmacol__113933Volatile and Phenolic Profiling of a Traditional Medicinal Plant, Hypericum empetrifolium with in vitro Biological Activities
Boiangiu_2021_Antioxidants.(Basel)_10_Anxiolytic, Promnesic, Anti-Acetylcholinesterase and Antioxidant Effects of Cotinine and 6-Hydroxy-L-Nicotine in Scopolamine-Induced Zebrafish (Danio rerio) Model of Alzheimer's Disease
Bojanowski_2021_JID.Innov_1_100040A Sensitization-Free Dimethyl Fumarate Prodrug, Isosorbide Di-(Methyl Fumarate), Provides a Topical Treatment Candidate for Psoriasis
Bolognino_2021_ChemMedChem__Synthesis and biological evaluation of dantrolene-like hydrazide and hydrazone analogues as multitarget agents for neurodegenerative diseases
Bondzic_2021_Chem.Biol.Interact__109708Cytotoxic activity and influence on acetylcholinesterase of series dinuclear platinum(II) complexes with aromatic nitrogen-containing heterocyclic bridging ligands: Insights in the mechanisms of action
Bone_2021_Bull.Entomol.Res__1Characterization of the pyrethroid resistance mechanisms in a Blattella germanica (Dictyoptera: Blattellidae) strain from Buenos Aires (Argentina)
Boneta_2021_J.Chem.Inf.Model__QM/MM Study of the Enzymatic Biodegradation Mechanism of Polyethylene Terephthalate
Bonfanti-Azzolin_2021_Toxicol.Ind.Health__7482337211053164Accelerated apoptosis, oxidative stress, and cholinergic inflammation in blood of metalworkers
Bononi_2021_Eur.J.Med.Chem_223_113679Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold
Bononi_2021_J.Med.Chem_64_9759alpha/beta-Hydrolase Domain (ABHD) Inhibitors as New Potential Therapeutic Options against Lipid-Related Diseases
Bonora_2021_J.Endocrinol.Invest__1Disentangling conflicting evidence on DPP-4 inhibitors and outcomes of COVID-19: narrative review and meta-analysis
Boos_2021_Med.Chem.Res_30_1166Dual monoamine oxidase B and acetylcholine esterase inhibitors for treating movement and cognition deficits in a C. elegans model of Parkinson's disease
Borah_2021_3.Biotech_11_240Analysing Curcuma caesia fractions and essential oil for neuroprotective potential against anxiety, depression, and amnesia
Borah_2021_CNS.Neurol.Disord.Drug.Targets__Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report
Borioni_2021_Bioorg.Chem_111_104893Design, synthesis and evaluation of cholinesterase hybrid inhibitors using a natural steroidal alkaloid as precursor
Borkowski_2021_Alzheimers.Res.Ther_13_149Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease
Borsini_2021_Brain.Behav.Immun.Health_16_100325The role of soluble epoxide hydrolase and its inhibitors in depression
Bortolami_2021_ACS.Chem.Neurosci__New Pyrimidine and Pyridine Derivatives as Multitarget Cholinesterase Inhibitors: Design, Synthesis, and In Vitro and In Cellulo Evaluation
Bortolami_2021_Expert.Opin.Ther.Pat__Acetylcholinesterase inhibitors for the treatment of Alzheimer's disease - a patent review (2016-present)
Bothos_2021_J.Transl.Med_19_151Clinical pharmacogenomics in action: design, assessment and implementation of a novel pharmacogenetic panel supporting drug selection for diseases of the central nervous system (CNS)
Bottasso_2021_Am.J.Physiol.Lung.Cell.Mol.Physiol__BMP4 and WNT signaling interact to promote mouse tracheal mesenchyme morphogenesis
Boughattas_2021_Sci.Total.Environ_796_148959Assessing the presence of microplastic particles in Tunisian agriculture soils and their potential toxicity effects using Eisenia andrei as bioindicator
Boukholda_2021_NanoImpact_24_100358Subacute silica nanoparticle exposure induced oxidative stress and inflammation in rat hippocampus combined with disruption of cholinergic system and behavioral functions
Boulajfene_2021_Life.(Basel)_11_Integrated Biomarker Response for Environmental Assessment Using the Gastropod Phorcus turbinatus along the Northern and the Northeastern Coasts of Tunisia
Boutoub_2021_Environ.Sci.Pollut.Res.Int_28_503Antioxidant activity and enzyme inhibitory potential of Euphorbia resinifera and E. officinarum honeys from Morocco and plant aqueous extracts
Boutoub_2021_Foods_10_Comparative Study of the Antioxidant and Enzyme Inhibitory Activities of Two Types of Moroccan Euphorbia Entire Honey and Their Phenolic Extracts
Bouwmeester_2021_Plant.Physiol_185_1292Adaptation of the parasitic plant lifecycle: germination is controlled by essential host signaling molecules
Bowles_2021_Protein.Sci__Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C
Bowroju_2021_Bioorg.Med.Chem_45_116311Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease
Boy_2021_Chem.Biodivers__Synthesis, spectroscopic analysis, and in vitro/in silico biological studies of novel piperidine derivatives heterocyclic Schiff-Mannich base compounds
Boyko_2021_Biomolecules_11_Structural and Biochemical Characterization of a Cold-Active PMGL3 Esterase with Unusual Oligomeric Structure
Braguy_2021_Methods.Mol.Biol_2309_201A Protoplast-Based Bioassay to Quantify Strigolactone Activity in Arabidopsis Using StrigoQuant
Brandao_2021_ACS.Med.Chem.Lett_12_1718Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors
Brandao_2021_Biotechnol.Prog_37_e3064Lipase activation by molecular bioimprinting: The role of interactions between fatty acids and enzyme active site
Brandt_2021_Drug.Test.Anal_13_175Synthetic cannabinoid receptor agonists: Analytical profiles and development of QMPSB, QMMSB, QMPCB, 2F-QMPSB, QMiPSB, and SGT-233
Brandts_2021_Mar.Pollut.Bull_173_113018A baseline study on the impact of nanoplastics on the portals of entry of xenobiotics in fish
Brawman-Mintzer_2021_J.Neurotrauma__Rivastigmine Transdermal Patch Treatment for Moderate to Severe Cognitive Impairment in Veterans with Traumatic Brain Injury (RiVET Study): A Randomized Clinical Trial
Bray_2021_Sci.Total.Environ_778_146087Sub-organism (acetylcholinesterase activity), population (survival) and chemical concentration responses reinforce mechanisms of antagonism associated with malathion toxicity
Brazzolotto_2021_Pharmacogenomics.J_21_165Characterization of four BCHE mutations associated with prolonged effect of suxamethonium
Breeschoten_2021_Genome.Biol.Evol__Expanding the menu: are polyphagy and gene family expansions linked across Lepidoptera?
Brejchova_2021_Proc.Natl.Acad.Sci.U.S.A_118_Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides
Bricher_2021_Front.Pharmacol_12_624895The Cholinergic Drug Pyridostigmine Alleviates Inflammation During LPS-Induced Acute Respiratory Distress Syndrome
Brinza_2021_Antioxidants.(Basel)_10_Bay Leaf (Laurus Nobilis L.) Incense Improved Scopolamine-Induced Amnesic Rats by Restoring Cholinergic Dysfunction and Brain Antioxidant Status
Brinza_2021_Plants.(Basel)_10_Baicalein 5,6-Dimethyl Ether Prevents Memory Deficits in the Scopolamine Zebrafish Model by Regulating Cholinergic and Antioxidant Systems
Brioschi_2021_Alzheimers.Res.Ther_13_172Protocols for cognitive enhancement. A user manual for Brain Health Services-part 5 of 6
Brito_2021_Genet.Mol.Biol_44_e20200367Expression of methyl farnesoate epoxidase (mfe) and juvenile hormone esterase (jhe) genes and their relation to social organization in the stingless bee Melipona interrupta (Hymenoptera: Apidae)
Britto_2021_Pest.Manag.Sci__Potential of Ficus carica extracts against Euschistus heros: toxicity of major active compounds and selectivity against beneficial insects
Brott_2021_Eng.Life.Sci__Engineering and evaluation of thermostable IsPETase variants for PET degradation
Brown_2021_Cell_184_5886From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease
Bruszt_2021_Psychopharmacology.(Berl)__Potentiation of cognitive enhancer effects of Alzheimer's disease medication memantine by alpha7 nicotinic acetylcholine receptor agonist PHA-543613 in the Morris water maze task
Bryant_2021_Science_372_Stepwise pathogenic evolution of Mycobacterium abscessus
Brzezinski-Sinai_2021_Sci.Rep_11_16687Cholinesterase activity in serum during general anesthesia in patients with or without vascular disease
Buchholz_2021_Authorea__Plastics degradation by hydrolytic enzymes: the Plastics-Active Enzymes Database - PAZy
Bukhari_2021_Eur.Rev.Med.Pharmacol.Sci_25_38351-trifluoromethoxyphenyl-3(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor attenuates high fat diet-induced cardiovascular and metabolic disorders in rats
Bures_2021_Pharmaceuticals.(Basel)_14_Dextran Sodium Sulphate-Induced Gastrointestinal Injury Further Aggravates the Impact of Galantamine on the Gastric Myoelectric Activity in Experimental Pigs
Burrows_2021_Genes.Brain.Behav__e12757Mice with an autism-associated R451C mutation in neuroligin-3 show a cautious but accurate response style in touchscreen attention tasks
Bursal_2021_Biometals__Transition metal complexes of a multidentate Schiff base ligand containing pyridine: synthesis, characterization, enzyme inhibitions, antioxidant properties, and molecular docking studies
Bursal_2021_Biophys.Chem_277_106629Enzyme inhibitory function and phytochemical profile of Inula discoidea using in vitro and in silico methods
Butcherine_2021_Aquat.Toxicol_242_106050Assessment of acetylcholinesterase, catalase, and glutathione S-transferase as biomarkers for imidacloprid exposure in penaeid shrimp
Butcherine_2021_Chemosphere_275_129918Acute toxicity, accumulation and sublethal effects of four neonicotinoids on juvenile Black Tiger Shrimp (Penaeus monodon)
Butler_2021_Contemp.Clin.Trials__106488Rationale, study design and implementation of the LUCINDA Trial: Leuprolide plus cholinesterase inhibition to reduce neurologic decline in Alzheimer's
Byrne_2021_Green.Chem_23_5043Enzyme-catalyzed synthesis of malonate polyesters and their use as metal chelating materials
Bzdrenga_2021_Molecules_26_657A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study
Bzowka_2021_Drug.Discov.Today__Computational insights into the known inhibitors of human soluble epoxide hydrolase
Cabodevilla_2021_J.Clin.Invest_131_Eruptive xanthoma model reveals endothelial cells internalize and metabolize chylomicrons, leading to extravascular triglyceride accumulation
Cabrera-Brandt_2021_Bull.Entomol.Res__1Changes in the genetic composition of Myzus persicae nicotianae populations in Chile and frequency of insecticide resistance mutations
Cacciatore_2021_RSC.Med.Chem_12_1944Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties
Cadez_2021_Sci.Rep_11_21486Assessment of four organophosphorus pesticides as inhibitors of human acetylcholinesterase and butyrylcholinesterase
Cafiero_2021_Curr.Genomics_22_557Could Small Neurotoxins-Peptides be Expressed during SARS-CoV-2 Infection?
Cagli_2021_Drug.Dev.Res__Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome-related pro-inflammatory and anti-inflammatory signaling pathways in the lipopolysaccharide-induced pain mouse model
Cahlikova_2021_Molecules_26_Recent Progress on Biological Activity of Amaryllidaceae and Further Isoquinoline Alkaloids in Connection with Alzheimer's Disease
Cai_2021_Anal.Chem__Capsulation of AuNCs with AIE Effect into Metal-Organic Framework for the Marriage of a Fluorescence and Colorimetric Biosensor to Detect Organophosphorus Pesticides
Cai_2021_Molecules_26_Bioactive Polyketide and Diketopiperazine Derivatives from the Mangrove-Sediment-Derived Fungus Aspergillus sp. SCSIO41407
Cairone_2021_Molecules_26_Health Potential of Clery Strawberries: Enzymatic Inhibition and Anti-Candida Activity Evaluation
Cakmak_2021_Liver.Int_41_905Chanarin-Dorfman Syndrome: A comprehensive review
Calabretta_2021_Anal.Chem__Ultrasensitive On-Field Luminescence Detection Using a Low-Cost Silicon Photomultiplier Device
Calaf_2021_Semin.Cancer.Biol__Role of organophosphorous pesticides and acetylcholine in breast carcinogenesis
Calahorro_2021_Toxicol.Rep_8_1240Impact of drug solvents on C. elegans pharyngeal pumping
Calderini_2021_Chembiochem__Simple plug-in synthetic step for the synthesis of (-)-camphor from renewable starting materials
Callizot_2021_Front.Pharmacol_12_681532Huperzia serrata Extract 'NSP01' With Neuroprotective Effects-Potential Synergies of Huperzine A and Polyphenols
Calsbeek_2021_Neurotoxicol__Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate
Camargo_2021_Rev.Soc.Bras.Med.Trop_54_e0201Influence of galantamine in the inflammatory process and tissular lesions caused by Trypanosoma cruzi QM2 strain
Campanari_2021_Cells_10_TDP-43 Regulation of AChE Expression Can Mediate ALS-Like Phenotype in Zebrafish
Campora_2021_ACS.Chem.Neurosci__Multitarget Biological Profiling of New Naphthoquinone and Anthraquinone-Based Derivatives for the Treatment of Alzheimer's Disease
Campora_2021_Pharmaceuticals.(Basel)_14_Journey on Naphthoquinone and Anthraquinone Derivatives: New Insights in Alzheimer's Disease
Camporesi_2021_Acta.Neuropathol.Commun_9_19Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers
Campos_2021_Toxicology__153033Protective Effects of Chrysin against the Neurotoxicity Induced by Aluminium: In Vitro and In Vivo Studies
Cannon_2021_Photochem.Photobiol__Caged Oxime Reactivators Designed for the Light Control of Acetylcholinesterase Reactivation
Cannon_2021_RSC.Med.Chem_12_1592Dual acting oximes designed for therapeutic decontamination of reactive organophosphates via catalytic inactivation and acetylcholinesterase reactivation
Cano-Lamadrid_2021_J.Sci.Food.Agric_101_2294Inhibition of enzymes associated with metabolic and neurological disorder by dried pomegranate sheets as a function of pomegranate cultivar and fruit puree
Cansiz_2021_Drug.Chem.Toxicol__1Morphine attenuates neurotoxic effects of MPTP in zebrafish embryos by regulating oxidant/antioxidant balance and acetylcholinesterase activity
Cao_2021_Bioorg.Med.Chem_35_116074Novel 3-benzylidene/benzylphthalide Mannich base derivatives as potential multifunctional agents for the treatment of Alzheimer's disease
Cao_2021_Environ.Sci.Technol__Can Organophosphates and Carbamates Cause Synergisms by Inhibiting Esterases Responsible for Biotransformation of Pyrethroids?
Cao_2021_Fitoterapia__104970Secondary metabolites of endophytic fungi isolated from Huperzia serrata
Cao_2021_Front.Endocrinol.(Lausanne)_12_731273Roles and Mechanisms of Dipeptidyl Peptidase 4 Inhibitors in Vascular Aging
Cao_2021_J.Cancer.Res.Clin.Oncol__Treatment efficacy and safety of regorafenib plus drug-eluting beads-transarterial chemoembolization versus regorafenib monotherapy in colorectal cancer liver metastasis patients who fail standard treatment regimens
Cao_2021_Mol.Ecol.Resour_21_834Chromosome-level genome of the peach fruit moth Carposina sasakii (Lepidoptera: Carposinidae) provides a resource for evolutionary studies on moths
Cao_2021_Toxicol.Lett_337_7Effect of superabsorbent polymers (SAP) and metal organic frameworks (MOF) wiping sandwich patch on human skin decontamination and detoxification in vitro
Capatina_2021_Molecules_26_Origanum vulgare ssp. hirtum (Lamiaceae) Essential Oil Prevents Behavioral and Oxidative Stress Changes in the Scopolamine Zebrafish Model
Capece_2021_J.Clin.Invest__Enhanced triacylglycerol catabolism by Carboxylesterase 1 promotes aggressive colorectal carcinoma
Capolupo_2021_Environ.Pollut_283_117081The sub-lethal impact of plastic and tire rubber leachates on the Mediterranean mussel Mytilus galloprovincialis
Capolupo_2021_Nanomaterials.(Basel)_11_A Comparative Assessment of the Chronic Effects of Micro- and Nano-Plastics on the Physiology of the Mediterranean Mussel Mytilus galloprovincialis
Cardellini_2021_ACS.Nano_15_16139A Modeling-Based Design to Engineering Protein Hydrogels with Random Copolymers
Cardenas_2021_Methods.Enzymol_648_423Screening and cultivating microbial strains able to grow on building blocks of polyurethane
Carmen_2021_J.Hazard.Mater_402_123534Microbial capability for the degradation of chemical additives present in petroleum-based plastic products: A review on current status and perspectives
Carniel_2021_Bioprocess.Biosyst.Eng_44_507Process strategies to improve biocatalytic depolymerization of post-consumer PET packages in bioreactors, and investigation on consumables cost reduction
Carniel_2021_Biotechnol.Adv__107811A comprehensive and critical review on key elements to implement enzymatic PET depolymerization for recycling purposes
Carvalho_2021_Biometals__Conjugates of desferrioxamine and aromatic amines improve markers of iron-dependent neurotoxicity
Carvalho_2021_J.Chem.Theory.Comput__Molecular Mechanism of Methanol Inhibition in CALB-Catalyzed Alcoholysis: Analyzing Molecular Dynamics Simulations by a Markov State Model
Carver_2021_Front.Neurosci_15_681144Blockade of TRPC Channels Limits Cholinergic-Driven Hyperexcitability and Seizure Susceptibility After Traumatic Brain Injury
Casey_2021_J.Lipid.Res__100049Lipid droplet membrane proteome remodeling parallels ethanol-induced hepatic steatosis and its resolution
Cash_2021_Neurobiol.Aging_103_31Clinicopathological correlations and cholinesterase expression in early-onset familial Alzheimer's disease with the presenilin 1 mutation, Leu235Pro
Cassano_2021_Clin.Mol.Allergy_19_24Angioedema associated with dipeptidyl peptidase-IV inhibitors
Cast_2021_J.Neurosci_41_392An Autism-Associated Mutation Impairs Neuroligin-4 Glycosylation and Enhances Excitatory Synaptic Transmission in Human Neurons
Castagna_2021_Clin.Drug.Investig__The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease
Castagna_2021_J.Alzheimers.Dis__A Retrospective Study on the Benefits of Combined Citicoline, Memantine, and Acetylcholinesterase Inhibitor Treatments in Older Patients Affected with Alzheimer's Disease
Castaneda_2021_Mar.Drugs_19_Bridging Cyanobacteria to Neurodegenerative Diseases: A New Potential Source of Bioactive Compounds against Alzheimer's Disease
Castle_2021_Sci.Total.Environ__151280High nutritional status promotes vitality of honey bees and mitigates negative effects of pesticides
Castro-Suarez_2021_Front.Neurol_12_786448Knowledge and Attitudes for the Management of Behavioral Variant of Frontotemporal Dementia
Castro_2021_Life.Sci__119421Modulatory effects of caffeic acid on purinergic and cholinergic systems and oxi-inflammatory parameters of streptozotocin-induced diabetic rats
Caswell_2021_Protein.Sci__Thioesterase enzyme families: Functions, structures, and mechanisms
Cations_2021_Sci.Rep_11_10674Using data linkage for national surveillance of clinical quality indicators for dementia care among Australian aged care users
Cattel_2021_Evol.Appl_14_1009A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: From genomic characterization to high-throughput field detection
Cavalcante_2021_Acta.Physiol.(Oxf)__e13663Benefits of pharmacological and electrical cholinergic stimulation in hypertension and heart failure
Cavalier_2021_Eur.J.Med.Chem_209_112908Lipolytic enzymes inhibitors: A new way for antibacterial drugs discovery
Cayetano_2021_Bioresour.Technol_332_125014Enhanced anaerobic digestion of waste-activated sludge via bioaugmentation strategy-Phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt2) analysis through hydrolytic enzymes and possible linkage to system performance
Cea-Rama_2021_Comput.Struct.Biotechnol.J_19_2307Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase
Celik_2021_Eur.J.Neurosci__Therapeutic effects of carvacrol on beta-amyloid-induced impairments in in-vitro and in-vivo models of Alzheimer's disease
Celik_2021_J.Biomol.Struct.Dyn__1New chalcone derivative, ethyl 2-(4-(3-(benzo[b]thiophen-2-yl)acryloyl)phenoxy)acetate: synthesis, characterization, DFT study, enzyme inhibition activities and docking study
Cendrowska-Pinkosz_2021_J.Trace.Elem.Med.Biol_67_126777The effect of the use of copper carbonate and copper nanoparticles in the diet of rats on the level of beta-amyloid and acetylcholinesterase in selected organs
Centeno-Betanzos_2021_Chem.Biodivers__Plants of the 'Libellus de Medicinalibus Indorum Herbis' from Mexico, 1552. Zephyranthes fosteri (Amaryllidaceae) Alkaloids
Cerqueira_2021_J.Biomol.Struct.Dyn__1Homology modeling, docking, molecular dynamics and in vitro studies to identify Rhipicephalus microplus acetylcholinesterase inhibitors
Ceyhun_2021_Arch.Pharm.(Weinheim)__e2100372Design and synthesis of novel chalcone derivatives and evaluation of their inhibitory activities against acetylcholinesterase
Cf_2021_Bioengineered_12_1040Bioprospecting of gut microflora for plastic biodegradation
Chagas_2021_Chemosphere_277_130279Multiple endpoints of polylactic acid biomicroplastic toxicity in adult zebrafish (Danio rerio)
Chahouri_2021_Mar.Pollut.Bull_174_113179Assessment of seasonal and spatial variation responses of integrated biomarkers in two marine sentinel bivalve species: Agadir Bay (Southern of Morocco)
Chaichompoo_2021_RSC.Adv_11_21153Stephapierrines A-H, new tetrahydroprotoberberine and aporphine alkaloids from the tubers of Stephania pierrei Diels and their anti-cholinesterase activities
Chakraborty_2021_Soft.Matter__Lipase sensing by naphthalene diimide based fluorescent organic nanoparticles: a solvent induced manifestation of self-assembly
Chalhoub_2021_J.Lipid.Res__100075Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease
Chandana_2021_Talanta_223_121701Comprehensive bioanalytical multi-imaging by planar chromatography in situ combined with biological and biochemical assays highlights bioactive fatty acids in abelmosk
Chang_2021_Extremophiles__Characterization of a carboxylesterase with hyper-thermostability and alkali-stability from Streptomyces lividans TK24
Chang_2021_Molecules_26_Regiospecific Positioning of Palmitic Acid in Triacylglycerol Structure of Enzymatically Modified Lipids Affects Physicochemical and In Vitro Digestion Properties
Chao_2021_ACS.Sens__BioChemPen for a Rapid Analysis of Compounds Supported on Solid Surfaces
Chao_2021_J.Food.Biochem__e14032Phenolic acids and flavonoids-rich Glechoma hederacea L. (Lamiaceae) water extract against H(2) O(2) -induced apoptosis in PC12 cells
Charles_2021_Redox.Biol_46_102107A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation
Charlie-Silva_2021_J.Hazard.Mater_419_126463Toxicological insights of Spike fragments SARS-CoV-2 by exposure environment: A threat to aquatic health?
Chatterjee_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_250_109164lambda cyhalothrin induced toxicity and potential attenuation of hematological, biochemical, enzymological and stress biomarkers in Cyprinus carpio L. at environmentally relevant concentrations: A multiple biomarker approach
Chauhan_2021_J.Lipids_2021_5583114Effects of Starvation on the Levels of Triglycerides, Diacylglycerol, and Activity of Lipase in Male and Female Drosophila Melanogaster
Chavarria_2021_Antioxidants.(Basel)_10_Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases
Chaves_2021_Curr.Med.Chem__Recent Multi-Target Approaches on the Development of Anti-Alzheimer`s Agents Integrating Metal Chelation Activity
Chebii_2021_J.Mol.Evol__Genome Scan for Variable Genes Involved in Environmental Adaptations of Nubian Ibex
Chekmarev_2021_Cells_10_The Oncogenic Signaling Disruptor, NDRG1: Molecular and Cellular Mechanisms of Activity
Chen_2021_Acta.Pharm.Sin.B_11_1686Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping
Chen_2021_Angew.Chem.Int.Ed.Engl__Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase
Chen_2021_Antioxidants.(Basel)_10_Effects of Black Garlic Extract and Nanoemulsion on the Deoxy Corticosterone Acetate-Salt Induced Hypertension and Its Associated Mild Cognitive Impairment in Rats
Chen_2021_Biomed.Res.Int_2021_6607386Risk Factors and a Nomogram Model Establishment for Postoperative Delirium in Elderly Patients Undergoing Arthroplasty Surgery: A Single-Center Retrospective Study
Chen_2021_Biomedicines_9_Hydrolysable Tannins Exhibit Acetylcholinesterase Inhibitory and Anti-Glycation Activities In Vitro and Learning and Memory Function Improvements in Scopolamine-Induced Amnesiac Mice
Chen_2021_Chem.Biodivers__e2100443Essential Oils from Spices Inhibit Cholinesterase Activity and Improve Behavioral Disorder in AlCl(3) Induced Dementia
Chen_2021_Chem.Sci_12_5202Synergistic enhancement of the emergency treatment effect of organophosphate poisoning by a supramolecular strategy
Chen_2021_Chemosphere_286_131866Tralopyril affects locomotor activity of zebrafish (Danio rerio) by impairing tail muscle tissue, the nervous system, and energy metabolism
Chen_2021_Ecotoxicol.Environ.Saf_208_111747Impacts of chronic exposure to sublethal diazepam on behavioral traits of female and male zebrafish (Danio rerio)
Chen_2021_Food.Chem_345_128560Fluorescent and colorimetric dual-response sensor based on copper (II)-decorated graphitic carbon nitride nanosheets for detection of toxic organophosphorus
Chen_2021_Front.Genet_12_740036Comparative Analyses of Sperm DNA Methylomes Among Three Commercial Pig Breeds Reveal Vital Hypomethylated Regions Associated With Spermatogenesis and Embryonic Development
Chen_2021_Front.Mol.Biosci_8_656440Regulation of Dynamic Protein S-Acylation
Chen_2021_Front.Neurol_12_719849Diagnosis and Treatment for Mild Cognitive Impairment: A Systematic Review of Clinical Practice Guidelines and Consensus Statements
Chen_2021_Front.Physiol_12_717119Soluble Epoxide Hydrolase Inhibitors Regulate Ischemic Arrhythmia by Targeting MicroRNA-1
Chen_2021_J.Am.Med.Dir.Assoc__Alzheimer's Disease THErapy With NEuroaid (ATHENE): A Randomized Double-Blind Delayed-Start Trial
Chen_2021_J.Hazard.Mater_402_123830Broad-spectrum pesticide screening by multiple cholinesterases and thiocholine sensors assembled high-throughput optical array system
Chen_2021_J.Hazard.Mater_413_125306Aggregation-induced emission luminogen@manganese dioxide core-shell nanomaterial-based paper analytical device for equipment-free and visual detection of organophosphorus pesticide
Chen_2021_J.Hazard.Mater_422_126929Atomically dispersed Fe/Bi dual active sites single-atom nanozymes for cascade catalysis and peroxymonosulfate activation to degrade dyes
Chen_2021_J.Lipid.Res__100068Apolipoprotein A5 lowers triglyceride levels via suppression of ANGPTL3/8-mediated LPL inhibition
Chen_2021_J.Pharm.Pharmacol_73_52Clock gene Bmal1 controls diurnal rhythms in expression and activity of intestinal carboxylesterase 1
Chen_2021_J.Surg.Res_270_221Sugammadex in Colorectal Surgery: A Systematic Review and Meta-analysis
Chen_2021_Methods.Enzymol_648_457Yeast cell surface display of bacterial PET hydrolase as a sustainable biocatalyst for the degradation of polyethylene terephthalate
Chen_2021_Mol.Metab__101426CES2 sustains HNF4alpha expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop
Chen_2021_NPJ.Parkinsons.Dis_7_103Cholinesterase inhibitors for gait, balance, and fall in Parkinson disease: a meta-analysis
Chen_2021_Nat.Catal_4_425General features to enhance enzymatic activity of poly(ethylene terephthalate) hydrolysis
Chen_2021_Nutr.Neurosci__1Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-alpha/NF-kappaB/caspase-3 signaling in type 2 diabetes rats
Chen_2021_Phytochemistry_186_112730Pyrrolyl 4-quinolone alkaloids from the mangrove endophytic fungus Penicillium steckii SCSIO 41025: Chiral resolution, configurational assignment, and enzyme inhibitory activities
Chen_2021_Proc.Natl.Acad.Sci.U.S.A_118_Evolution of Ycf54-independent chlorophyll biosynthesis in cyanobacteria
Chen_2021_Sci.Rep_11_13984Copy number variation in the CES1 gene and the risk of non-alcoholic fatty liver in a Chinese Han population
Chen_2021_Sci.Total.Environ_794_148719High-efficiency degradation of phthalic acid esters (PAEs) by Pseudarthrobacter defluvii E5: Performance, degradative pathway, and key genes
Chen_2021_Sci.Total.Environ__152681Long-term exposure to polyethylene microplastics and glyphosate interferes with the behavior, intestinal microbial homeostasis, and metabolites of the common carp (Cyprinus carpio L.)
Chen_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_269_120756Ultrasensitive detection of butyrylcholinesterase activity based on self-polymerization modulated fluorescence of sulfur quantum dots
Chen_2021_Virulence_12_1563A novel transcription factor UvCGBP1 regulates development and virulence of rice false smut fungus Ustilaginoidea virens
Cheng_2021_Anal.Methods__Biomimetic self-assembly of lipase-zeolitic imidazolate frameworks with enhanced biosensing of protox inhibiting herbicides
Cheng_2021_Enzyme.Microb.Technol_154_109962Synthesis of highly active enzyme-metal nanohybrids and uncovering the design rules
Cheng_2021_J.Pharm.Sci__Identification of key excipients for the solubilization and structural characterization of lipoprotein lipase, an enzyme for hydrolysis of triglyceride
Cheng_2021_Sci.Total.Environ_768_144945Insights into mechanisms involved in the uptake, translocation, and metabolism of phthalate esters in Chinese cabbage (Brassica rapa var. chinensis)
Cheon_2021_Nanomaterials.(Basel)_11_Highly Sensitive Fluorescent Detection of Acetylcholine Based on the Enhanced Peroxidase-Like Activity of Histidine Coated Magnetic Nanoparticles
Cherkashyna_2021_Pol.Merkur.Lekarski_49_411Informativeness of structural and biochemical changes in the muscle tissue of myocardium in the early postmortem period
Chernicharo_2021_J.Mass.Spectrom_56_e4779Simulation of the electron ionization mass spectra of the Novichok nerve agent
Chertemps_2021_Comp.Biochem.Physiol.Part.D.Genomics.Proteomics_40_100867Detoxification gene families in Phylloxera: Endogenous functions and roles in response to the environment
Chiang_2021_J.Gen.Physiol_153_Recordings from neuron-HEK cell cocultures reveal the determinants of miniature excitatory postsynaptic currents
Chiara_2021_Sci.Rep_11_9711nAChRs gene expression and neuroinflammation in APPswe/PS1dE9 transgenic mouse
Chigurupati_2021_Saudi.J.Biol.Sci_28_5579Pharmacological and pharmacognostical valuation of Canna indica leaves extract by quantifying safety profile and neuroprotective potential
Chintalchere_2021_Proc.Natl.Acad.Sci.India.Sect.B.Biol.Sci__1Bioefficacy of Lemongrass and Tea Tree Essential Oils Against House Fly, Musca domestica
Choi_2021_BMC.Anesthesiol_21_93Comparison of neuromuscular blockade recovery co-administered with neostigmine and different doses of calcium gluconate: a randomized control trial
Choi_2021_J.Agric.Food.Chem__Integral Stereoselectivity of Lipase Based on the Chromatographic Resolution of Enantiomeric/Regioisomeric Diacylglycerols
Choi_2021_J.Bone.Miner.Res__Notum deletion from late-stage skeletal cells increases cortical bone formation and potentiates skeletal effects of sclerostin inhibition
Choi_2021_Mar.Environ.Res_168_105320Impact of polyethylene terephthalate microfiber length on cellular responses in the Mediterranean mussel Mytilus galloprovincialis
Choi_2021_Nutrients_13_Allium hookeri Extracts Improve Scopolamine-Induced Cognitive Impairment via Activation of the Cholinergic System and Anti-Neuroinflammation in Mice
Chopra_2021_Neurochem.Res__N-Acetylcysteine Ameliorates Neurotoxic Effects of Manganese Intoxication in Rats: A Biochemical and Behavioral Study
Choquer_2021_Environ.Microbiol__The infection cushion of Botrytis cinerea: a fungal weapon of plant-biomass destruction
Choubey_2021_Bioorg.Chem_111_104922Design, synthesis, and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatment of Alzheimer's disease
Choudhary_2021_Ann.Lab.Med_41_129Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19
Choudhir_2021_J.Biomol.Struct.Dyn__1A combinatorial approach to screen structurally diverse acetylcholinesterase inhibitory plant secondary metabolites targeting Alzheimer's disease
Chowdhury_2021_Eur.J.Med.Chem_222_113541Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Abeta antiaggregant
Chretien_2021_Br.J.Clin.Pharmacol_87_2830Disproportionality analysis in VigiBase as a drug repositioning method for the discovery of potentially useful drugs in Alzheimer's disease
Chrzanowski-Smith_2021_Exp.Physiol_106_1208Resting skeletal muscle PNPLA2 (ATGL) and CPT1B are associated with peak fat oxidation rates in men and women but do not explain observed sex differences
Chung_2021_World.J.Diabetes_12_1818Organophosphate pesticides and new-onset diabetes mellitus: From molecular mechanisms to a possible therapeutic perspective
Chupeerach_2021_Foods_10_The Effect of Steaming and Fermentation on Nutritive Values, Antioxidant Activities, and Inhibitory Properties of Tea Leaves
Ciftci_2021_Anticancer.Agents.Med.Chem__Apoptotic Effect of Novel Benzimidazole Derivatives Bearing Pyridyl/Pyrimidinyl Piperazine Moiety
Cikcikoglu_2021_Int.J.Environ.Health.Res__1The use of Gammarus pulex as a model organism for ecotoxicological assessment of ibuprofen and propranolol at environmental relevant concentrations
Cioffi_2021_Environ.Sci.Technol__Office Paper-Based Electrochemical Strips for Organophosphorus Pesticide Monitoring in Agricultural Soil
Cizkova_2021_Cells.Tissues.Organs__1Soluble Epoxide Hydrolase as an Important Player in Intestinal Cell Differentiation
Clarke_2021_Genes.(Basel)_13_LRRTM4 Terminal Exon Duplicated in Family with Tourette Syndrome, Autism and ADHD
Closset_2021_Int.J.Mol.Sci_23_Effects of Aluminium Contamination on the Nervous System of Freshwater Aquatic Vertebrates: A Review
Cobilinschi_2021_Acta.Endocrinol.(Buchar)_17_177ENDOCRINE DISTURBANCES INDUCED BY LOW-DOSE ORGANOPHOSPHATE EXPOSURE IN MALE WISTAR RATS
Codony_2021_J.Med.Chem__From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis
Cogan_2021_Science_374_729Mapping the catalytic conformations of an assembly-line polyketide synthase module
Collins_2021_Drug.Metab.Dispos__Transcriptional regulation of carboxylesterase 1 (CES1) in human liver: role of the nuclear receptor NR1H3 (LXRalpha) and its splice isoforms
Contreras-Aguilar_2021_Animal_15_100236Changes in saliva biomarkers during a standardized increasing intensity field exercise test in endurance horses
Contreras-Aguilar_2021_Animals.(Basel)_11_Changes in Saliva Analytes in Dairy Cows during Peripartum: A Pilot Study
Contreras-Aguilar_2021_Vet.J_273_105679Changes in saliva analytes during pregnancy, farrowing and lactation in sows: A sialochemistry approach
Coors_2021_Environ.Toxicol.Chem__Evidence for Specific Receptor-Mediated Toxicity of Pharmaceuticals in Aquatic Organisms Derived from Acute and Chronic Standard Endpoints
Coppi_2021_J.Neurochem_157_1182Acetylcholine modulates K(+) and Na(+) currents in human basal forebrain cholinergic neuroblasts through an autocrine/paracrine mechanism
Corrado_2021_Chembiochem__High regio- and stereoselective multi-enzymatic synthesis of all phenylpropanolamine stereoisomers from beta-methylstyrene
Cortes-Gomez_2021_J.Neurochem_157_2091Tau phosphorylation by glycogen synthase kinase 3beta modulates enzyme acetylcholinesterase expression
Coskun_2021_Appl.Biochem.Biotechnol_193_430Immobilization of Candida antarctica Lipase on Nanomaterials and Investigation of the Enzyme Activity and Enantioselectivity
Costa_2021_Annu.Rev.Pharmacol.Toxicol_61_1Introduction to the Theme Old and New Toxicology: Interfaces with Pharmacology
Costas-Ferreira_2021_Int.J.Mol.Sci_22_Neurotoxic Effects of Neonicotinoids on Mammals: What Is There beyond the Activation of Nicotinic Acetylcholine Receptors?-A Systematic Review
Coughlin_2021_Eur.J.Nucl.Med.Mol.Imaging__First-in-human neuroimaging of soluble epoxide hydrolase using [(18)F]FNDP PET
Courties_2021_Sci.Rep_11_11886Regulation of the acetylcholine/alpha7nAChR anti-inflammatory pathway in COVID-19 patients
Covey_2021_J.Neurosci__Chronic augmentation of endocannabinoid levels persistently increases dopaminergic encoding of reward cost and motivation
Crea_2021_Eur.Heart.J_42_1119New therapeutic targets in lipid lowering: high-sugar feeding in infants, lipoprotein(a), and lipoprotein lipase
Crews_2021_Front.Behav.Neurosci_15_652494Loss of Basal Forebrain Cholinergic Neurons Following Adolescent Binge Ethanol Exposure: Recovery With the Cholinesterase Inhibitor Galantamine
Crowther_2021_BJPsych.Bull__1Cardiac monitoring in memory clinics: national survey of UK practice
Cruces-Solis_2021_FASEB.J_35_e21585Altered theta and beta oscillatory synchrony in a genetic mouse model of pathological anxiety
Cuello_2021_Proc.Natl.Acad.Sci.U.S.A_118_Leslie Iversen, a friend of friends and an inspiring light in neuropharmacology
Cui_2021_ACS.Catal_11_1340Computational redesign of a PETase for plastic biodegradation under ambient condition by the GRAPE strategy
Cui_2021_Angew.Chem.Int.Ed.Engl__Less unfavorable salt-bridges on the enzyme surface results in more organic cosolvent resistance
Cui_2021_Chemistry_27_2789CompassR Yields Highly Organic-Solvent-Tolerant Enzymes through Recombination of Compatible Substitutions
Cui_2021_Food.Chem_366_130523A novel sn-1,3 specific lipase from Janibacter sp. as catalysts for the high-yield synthesis of long-medium-long type structured triacylglycerols
Cui_2021_Hypertension_78_1527Inhibition of Soluble Epoxide Hydrolase Attenuates Bosutinib-Induced Blood Pressure Elevation
Cui_2021_Molecules_26_Endophytic Fungal Community of Huperzia serrata: Diversity and Relevance to the Production of Huperzine A by the Plant Host
Cumming_2021_J.Biotechnol_325_217Lipase-catalysed synthesis of mono- and di-acyl esters of glyceryl caffeate in propylene carbonate and their antioxidant properties in tuna oil
Cunha_2021_J.Hazard.Mater__127753From carrion-eaters to plastic material plunderers: Toxicological impacts of plastic ingestion on black vultures, Coragyps atratus (Cathartiformes: Cathartidae)
Cuttler_2021_Open.Biol_11_210091Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders
Dachir_2021_Chem.Biol.Interact_336_109393Skin decontamination efficacy of sulfur mustard and VX in the pig model: A comparison between Fuller's earth and RSDL
Dada_2021_J.Complement.Integr.Med__Evaluation of different almond (Terminalia catappa) extracts against oxidative stress induced by cyclosporine in brain and liver of rats
Dagar_2021_Bioinformation_17_776Molecular docking analysis of modified gedunin from neem with snake venom enzymes
Dahleh_2021_Free.Radic.Res__1Exercise associated with gamma-oryzanol supplementation suppresses oxidative stress and prevents changes in locomotion in Drosophila melanogaster
Dai_2021_Dyes.Pigments_192_109444Detection of carboxylesterase 1 and carbamates with a novel fluorescent protein chromophore based probe
Dai_2021_Insects_12_Expression Levels of Detoxification Enzyme Genes from Dendroctonus armandi (Coleoptera: Curculionidae) Fed on a Solid Diet Containing Pine Phloem and Terpenoids
Dai_2021_Insects_13_Genome-Wide Selective Signature Analysis Revealed Insecticide Resistance Mechanisms in Cydia pomonella
Dai_2021_J.Biotechnol_334_47Enhancing PET hydrolytic enzyme activity by fusion of the cellulose-binding domain of cellobiohydrolase I from Trichoderma reesei
Dai_2021_J.Neurosurg.Sci__Preliminary study of the consciousness-promotion mechanism of electroacupuncture in comatose patients with diffuse axonal injuries
Dai_2021_Methods.Mol.Biol_2356_199Isolation and Functional Analysis of Effector Proteins of Magnaporthe oryzae
Dai_2021_Talanta_223_121744Construction of a red emission fluorescent protein chromophore-based probe for detection of carboxylesterase 1 and carbamate pesticide in culture cells
Dail_2021_J.Biochem.Mol.Toxicol__e22755Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression
Dall'Acqua_2021_Chem.Biodivers__Phytochemical investigations and in vitro bioactivity screening on Melia azedarach L. leaves extract from Nepal
Dall'Acqua_2021_Front.Pharmacol_12_660735Hypericum triquetrifolium and H. neurocalycinum as Sources of Antioxidants and Multi-Target Bioactive Compounds: A Comprehensive Characterization Combining In Vitro Bioassays and Integrated NMR and LC-MS Characterization by Using a Multivariate Approach
Dall'Acqua_2021_Molecules_26_Evaluation of Antioxidant and Enzyme Inhibition Properties of Croton hirtus L'Hr. Extracts Obtained with Different Solvents
Daly_2021_Biotechnol.Adv__107770From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi
Dang_2021_Front.Cell.Dev.Biol_9_662763NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas
Dang_2021_J.Econ.Entomol__Multiple Mechanisms Conferring Broad-Spectrum Insecticide Resistance in the Tropical Bed Bug (Hemiptera: Cimicidae)
Dao_2021_Animals.(Basel)_11_Understanding the Role of Prevotella Genus in the Digestion of Lignocellulose and Other Substrates in Vietnamese Native Goats' Rumen by Metagenomic Deep Sequencing
Daroi_2021_Alzheimers.Dement_17 Suppl 12_e058603p-Coumaric acid protects against D-galactose induced neurotoxicity by attenuating neuroinflammation and apoptosis in mice brain
Das_2021_Neurotoxicol__Dihydroactinidiolide regulates Nrf2/HO-1 expression and inhibits caspase-3/Bax pathway to protect SH-SY5Y human neuroblastoma cells from oxidative stress induced neuronal apoptosis
Dash_2021_J.Ethnopharmacol_282_114637The modulatory role of prime identified compounds in Geophila repens in mitigating scopolamine-induced neurotoxicity in experimental rats of Alzheimer's disease via attenuation of cholinesterase, beta-secretase, MAPt levels and inhibition of oxidative stress imparts inflammation
Dassanayake_2021_Clin.Toxicol.(Phila)__1Changes of attention-related brain activity over 6 months after acute organophosphate pesticide poisoning: a prospective follow-up study
David_2021_J.Enzyme.Inhib.Med.Chem_36_491Discovery of new acetylcholinesterase inhibitors for Alzheimer's disease: virtual screening and in vitro characterisation
Davis_2021_Int.J.Mol.Sci_22_Soluble Epoxide Hydrolase Blockade after Stroke Onset Protects Normal but Not Diabetic Mice
Dawoud_2021_Rep.Biochem.Mol.Biol_10_506Hepatoprotective Effects of Chitosan and Chitosan Nanoparticles against Biochemical, Genetic, and Histological Disorders Induced by the Toxicity of Emamectin Benzoate
De Anna_2021_Pestic.Biochem.Physiol_178_104920The insecticide chlorpyrifos modifies the expression of genes involved in the PXR and AhR pathways in the rainbow trout, Oncorhynchus mykiss
De Boer_2021_Biomolecules_11_A Comprehensive Review of Cholinesterase Modeling and Simulation
De Marchi_2021_Environ.Sci.Pollut.Res.Int__A multi-bioassay integrated approach to assess antifouling potential of extracts from the Mediterranean sponge Ircinia oros
De Pasqual_2021_Trends.Ecol.Evol_36_848Evolutionary importance of intraspecific variation in sex pheromones
De Simone_2021_Int.J.Mol.Sci_22_Serum Albumin: A Multifaced Enzyme
De Zutter_2021_Cancers.(Basel)_13_The Role of Post-Translational Modifications of Chemokines by CD26 in Cancer
Dean_2021_J.Acad.Consult.Liaison.Psychiatry_62_449Psychiatric Sequelae of Anti-Dipeptidyl Peptidase-Like Protein-6 Encephalitis: A Case Report and Review of the Literature
Deb_2021_Pharmaceuticals.(Basel)_14_ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential
Decalf_2021_Bioorg.Chem_116_105376A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants
Decarpigny_2021_Colloids.Surf.B.Biointerfaces_200_111606Oxidation of 2,5-diformfylfuran to 2,5-furandicarboxylic acid catalyzed by Candida antarctica Lipase B immobilized in a cyclodextrin-templated mesoporous silica. The critical role of pore characteristics on the catalytic performance
Decio_2021_Ecotoxicol.Environ.Saf_223_112581Enzymatic responses in the head and midgut of Africanized Apis mellifera contaminated with a sublethal concentration of thiamethoxam
Delerue_2021_Food.Res.Int_140_109857Interactions between Ginkgo biloba L. and Scutellaria baicalensis Georgi in multicomponent mixtures towards cholinesterase inhibition and ROS scavenging
Dell'Oste_2021_Molecules_26_Strigolactones, from Plants to Human Health: Achievements and Challenges
Della Pietra_2021_Int.J.Mol.Sci_22_Distinct Activity of Endocannabinoid-Hydrolyzing Enzymes MAGL and FAAH in Key Regions of Peripheral and Central Nervous System Implicated in Migraine
Della Vechia_2021_Pestic.Biochem.Physiol_175_104855The role of detoxification enzymes in the susceptibility of Brevipalpus californicus exposed to acaricide and insecticide mixtures
Dellali_2021_Environ.Sci.Pollut.Res.Int_28_18176Effects of Au/TiO(2) metallic nanoparticles on Unio ravoisieri: assessment through an oxidative stress and toxicity biomarkers
Dellali_2021_Environ.Sci.Pollut.Res.Int_28_36523Acute toxicity and biomarker responses in Gammarus locusta amphipods exposed to copper, cadmium, and the organochlorine insecticide dieldrin
Demir Caltekin_2021_J.Obstet.Gynaecol.Res__The protective effect of JZL184 on ovarian ischemia reperfusion injury and ovarian reserve in rats
Demir-Yazici_2021_Future.Med.Chem__Synthesis, molecular modeling and cholinesterase inhibitory effects of 2-indolinone-based hydrazinecarbothioamides
Demir_2021_Turk.J.Biol_45_275Polyhydroxyalkanoate accumulation in Streptomyces coelicolor affected by SCO7613 gene region
Deng_2021_Cannabis.Cannabinoid.Res__ABHD6 Controls Amphetamine-Stimulated Hyperlocomotion: Involvement of CB(1) Receptors
Deng_2021_Toxins.(Basel)_13_Lipolytic Activity of a Carboxylesterase from Bumblebee (Bombus ignitus) Venom
Denlinger_2021_Evol.Appl_14_1248Standing genetic variation in laboratory populations of insecticide-susceptible Phlebotomus papatasi and Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae) for the evolution of resistance
Deo_2021_Nat.Chem.Biol_17_718The HaloTag as a general scaffold for far-red tunable chemigenetic indicators
Deprey_2021_Bioconjug.Chem__HaloTag Forms an Intramolecular Disulfide
Deuther-Conrad_2021_RSC.Med.Chem_12_1000Studies on the affinity of 6-[(n-(cyclo)aminoalkyl)oxy]-4H-chromen-4-ones for sigma 1/2 receptors
Devidas_2021_Eur.J.Pharmacol__174234Amelioration of cognitive deficit in zebrafish by an undescribed anthraquinone from Juglans regia L.: An in-silico, in-vitro and in-vivo approach
Devita_2021_Aging.Clin.Exp.Res__Acetylcholinesterase inhibitors and cognitive stimulation, combined and alone, in treating individuals with mild Alzheimer's disease
Dey_2021_Vet.Parasitol_296_109461A kaempferol derivative isolated from Lysimachia ramosa (Wall ex. Duby) induced alteration of acetylcholinesterase and nitric oxide synthase in Raillietina echinobothrida
Dhaliwal_2021_Inflammopharmacology__Dimethyl fumarate attenuates 2-VO-induced vascular dementia via activating the Nrf2 signaling pathway in rats
Dhami_2021_Curr.Alzheimer.Res__Neuroprotective Effect of Fucoxanthin against Intracerebroventricular Streptozotocin (ICV-STZ) Induced Cognitive Impairment in Experimental Rats
Dhamodharan_2021_Mol.Divers__Machine learning models for predicting the activity of AChE and BACE1 dual inhibitors for the treatment of Alzheimer's disease
Dhanasobhon_2021_Neurobiol.Dis__105363Enhanced analgesic cholinergic tone in the spinal cord in a mouse model of neuropathic pain
Dhandapani_2021_RSC.Adv_11_16285Targeted esterase-induced dye (TED) loading supports direct calcium imaging in eukaryotic cell-free systems
Dhar_2021_Dysphagia__Effects of Pyridostigmine on Esophageal and Pharyngeal Motility in Dysphagic Patients Undergoing High-Resolution Manometry
Dhuria_2021_Drug.Metab.Rev__1Recent developments in predicting CYP-Independent metabolism
Di Consiglio_2021_Toxicol.Lett__Human Variability in Carboxylesterases and carboxylesterase-related Uncertainty Factors for Chemical Risk Assessment
Di Rocco_2021_Hum.Mol.Genet__Caenorhabditis elegans provides an efficient drug screening platform for GNAO1-related disorders and highlights the potential role of caffeine in controlling dyskinesia
Diaconu_2021_J.Enzyme.Inhib.Med.Chem_36_68Lipoprotein-associated phospholipase A2 (Lp-PLA2) - possible diagnostic and risk biomarker in chronic ischaemic heart disease
Dias_2021_Environ.Monit.Assess_193_317DNA damage and biochemical responses in estuarine bivalve Donax incarnatus (Gmelin, 1791) exposed to sub-lethal concentrations of an organophosphate pesticide monocrotophos
Diez-Buitrago_2021_Talanta_225_122029Development of portable CdS QDs screen-printed carbon electrode platform for electrochemiluminescence measurements and bioanalytical applications
Ding_2021_ACS.Chem.Neurosci__((E)-N-(4-(((2-Amino-5-phenylpyridin-3-yl)imino)methyl)pyridin-2-yl)cyclopropanecarboxamide) Ameliorated Abeta(1-42)-Induced Alzheimer's Disease in SD Rats by Inhibiting Oxidative Stress and Apoptosis
Ding_2021_Am.J.Pathol_191_353Lysosomal Acid Lipase Deficiency Controls T- and B-Regulatory Cell Homeostasis in the Lymph Nodes of Mice with Human Cancer Xenotransplants
Ding_2021_Bioorg.Med.Chem_41_116216Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT)
Ding_2021_Chemosphere_289_133130Biodegradation of lambda-cyhalothrin through cell surface display of bacterial carboxylesterase
Ding_2021_J.Comp.Neurol__Cellular resolution anatomical and molecular atlases for prenatal human brains
Ding_2021_Nat.Metab__Peroxisomal beta-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis
Ding_2021_Pest.Manag.Sci__Characterization of the insecticide detoxification carboxylesterase Boest1 from Bradysia odoriphaga Yang et Zhang (Diptera:Sciaridae)
Ding_2021_Pestic.Biochem.Physiol_174_104807Characterization and functional analysis of two acetylcholinesterase genes in Bradysia odoriphaga Yang et Zhang (Diptera: Sciaridae)
Diodato_2021_Environ.Sci.Pollut.Res.Int__Integrated biomarker response in Mytilus chilensis exposed to untreated urban discharges along the coast of Ushuaia Bay (Beagle Channel, Argentina)
Dissanayake_2021_Clin.Toxicol.(Phila)__1Impaired neuromuscular function by conjoint actions of organophosphorus insecticide metabolites omethoate and cyclohexanol with implications for treatment of respiratory failure
Diwo_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2017046118NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB
Dixit_2021_Protein.Pept.Lett_28_315Interaction of Human Alpha-2-Macroglobulin with Pesticide Aldicarb Using Spectroscopy and Molecular Docking
Dixon_2021_Genes.(Basel)_12_The Role of Lipid Sensing Nuclear Receptors (PPARs and LXR) and Metabolic Lipases in Obesity, Diabetes and NAFLD
Djafarou_2021_J.Biomol.Struct.Dyn__1Computational design of new tacrine analogs: an in silico prediction of their cholinesterase inhibitory, antioxidant, and hepatotoxic activities
Djapovic_2021_Chemosphere_275_130005Synthesis and characterization of polyethylene terephthalate (PET) precursors and potential degradation products: Toxicity study and application in discovery of novel PETases
Djebbi_2021_Environ.Sci.Pollut.Res.Int__Effects of nickel oxide nanoparticles on survival, reproduction, and oxidative stress biomarkers in the marine calanoid copepod Centropages ponticus under short-term exposure
Dodson_2021_Pediatr.Emerg.Care_37_e206That's Not His Regular Formula: A Case of Organophosphate Poisoning in an Infant
Doerr_2021_J.Mol.Model_27_198Effect of the acyl-group length on the chemoselectivity of the lipase-catalyzed acylation of propranolol-a computational study
Dolar_2021_Sci.Total.Environ_772_144900Microplastics, chlorpyrifos and their mixtures modulate immune processes in the terrestrial crustacean Porcellio scaber
Dolezal_2021_J.Biomol.Struct.Dyn__1Accuracy and precision of binding free energy prediction for a tacrine related lead inhibitor of acetylcholinesterase with an arsenal of supercomputerized molecular modelling methods: a comparative study
Doltchinkova_2021_Membranes.(Basel)_11_Surface Properties of Synaptosomes in the Presence of L-Glutamic and Kainic Acids: In Vitro Alteration of the ATPase and Acetylcholinesterase Activities
Dominguez_2021_Neurotoxicol_84_30Neurobehavioral and neurochemical effects in rats offspring co-exposed to arsenic and fluoride during development
Dong_2021_ACS.Appl.Mater.Interfaces__Binding Peptide-Guided Immobilization of Lipases with Significantly Improved Catalytic Performance Using Escherichia coli BL21(DE3) Biofilms as a Platform
Dong_2021_Acta.Crystallogr.D.Struct.Biol_77_267Crystal structure of fungal tannase from Aspergillus niger
Dong_2021_BMJ.Open_11_e042765Prognostic nomogram for the severity of acute organophosphate insecticide self-poisoning: a retrospective observational cohort study
Dong_2021_Biomed.Chromatogr__e5229Enantioselective determination of phenthoate enantiomers in plant-origin matrices using reversed-phase high performance liquid chromatography-tandem mass spectrometry
Dong_2021_Chem.Phys.Lipids_239_105103Platelet activating-factor acetylhydrolase II: A member of phospholipase A2 family that hydrolyzes oxidized phospholipids
Dong_2021_Int.J.Mol.Sci_22_The Cutinase Bdo_10846 Play an Important Role in the Virulence of Botryosphaeria dothidea and in Inducing the Wart Symptom on Apple Plant
Dong_2021_PLoS.Pathog_17_e1009645NDRG1 facilitates lytic replication of Kaposi's sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase
Dong_2021_World.J.Emerg.Med_12_24Clinical correlates of hypotension in patients with acute organophosphorus poisoning
Dongus_2021_Curr.Opin.Plant.Biol_62_102039EDS1 signalling: At the nexus of intracellular and surface receptor immunity
Donskov_2021_Acta.Neurol.Scand__Overactive bladder in patients with myasthenia gravis-A cross-sectional population-based study
Dora_2021_Int.J.Mol.Sci_22_Quercetin Attenuates Brain Oxidative Alterations Induced by Iron Oxide Nanoparticles in Rats
Dos Santos_2021_Int.J.Mol.Sci_22_Selective Extraction of Piceatannol from Passiflora edulis by-Products: Application of HSPs Strategy and Inhibition of Neurodegenerative Enzymes
Dos Santos_2021_Life.Sci__119386Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents
Dos_2021_Nat.Prod.Res__1Acetylcholinesterase and butyrylcholinesterase inhibition by nectriapyrone and tryptophol isolated from endophytic fungus Phomopsis sp
Dost_2021_Curr.Alzheimer.Res__Theracurmin supplementation may be a therapeutic option for older patients with Alzheimer's disease: a 6-month retrospective follow-up study
Dou_2021_Org.Lett__Kinetic Resolution of Nearly Symmetric 3-Cyclohexene-1-carboxylate Esters Using a Bacterial Carboxylesterase Identified by Genome Mining
Du_2021_Circ.Res__A Neuroligin Isoform Translated by circNlgn Contributes to Cardiac Remodeling
Du_2021_Eur.J.Med.Chem_223_113678Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis
Duan_2021_Foods_10_Characterization of Feruloyl Esterase from Bacillus pumilus SK52.001 and Its Application in Ferulic Acid Production from De-Starched Wheat Bran
Dubrana_2021_ACS.Chem.Neurosci__An Antidote Screening System for Organophosphorus Poisoning Using Zebrafish Larvae
Ducrot_2021_FASEB.J_35_e21791Dopaminergic neurons establish a distinctive axonal arbor with a majority of non-synaptic terminals
Dudai_2021_J.Neurochem_158_1320Cortical VIP(+) /ChAT(+) interneurons: From genetics to function
Dudi-Venkata_2021_Colorectal.Dis__PyRICo-Pilot - Pyridostigmine to reduce the duration of postoperative ileus after colorectal surgery - a phase II study
Duplaine_2021_Neurol.Sci__Myasthenia Gravis Lambert-Eaton overlap syndrome induced by nivolumab in a metastatic melanoma patient
Durand_2021_J.Exp.Biol__Neuroligin 1 expression is linked to plasticity of behavioral and neuronal responses to sex pheromone in the male moth Agrotis ipsilon
Dutta_2021_Front.Plant.Sci_12_714730Deciphering the Behavioral Response of Meloidogyne incognita and Fusarium oxysporum Toward Mustard Essential Oil
Dwyer_2021_Angew.Chem.Int.Ed.Engl_60_3071Chemoproteomics-Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism
Dymek_2021_Molecules_26_1626Optimization of Pressurized Liquid Extraction of Lycopodiaceae Alkaloids Obtained from Two Lycopodium Species
Dymek_2021_Molecules_26_6379Fractionation of Lycopodiaceae Alkaloids and Evaluation of Their Anticholinesterase and Cytotoxic Activities
Ebadollahi_2021_Int.J.Environ.Res.Public.Health_18_Acaricidal, Insecticidal, and Nematicidal Efficiency of Essential Oils Isolated from the Satureja Genus
Eddleston_2021_Lancet_397_175Organophosphorus poisoning: the wet opioid toxidrome
Edin_2021_J.Biol.Chem_296_100198Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function
Edinoff_2021_Anesth.Pain.Med_11_e117146Adjuvant Drugs for Peripheral Nerve Blocks: The Role of NMDA Antagonists, Neostigmine, Epinephrine, and Sodium Bicarbonate
Edmison_2021_Brain.Sci_11_Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias
Edres_2021_Environ.Sci.Pollut.Res.Int__The potential neuroprotective effect of allicin and melatonin in acrylamide-induced brain damage in rats
Efjestad_2021_Front.Pharmacol_12_791578Use of Drugs With Risk of Heart Rate-Related Problems is Common in Norwegian Dementia Patients Treated With Acetylcholinesterase Inhibitors: A Prevalence Study Based on the Norwegian Prescription Database
Efjestad_2021_PLoS.One_16_e0243804Sex differences in psychotropic and analgesic drug use before and after initiating treatment with acetylcholinesterase inhibitors
Efremenko_2021_Toxins.(Basel)_13_Using Cholinesterases and Immobilized Luminescent Photobacteria for the Express-Analysis of Mycotoxins and Estimating the Efficiency of Their Enzymatic Hydrolysis
Ehiguese_2021_Environ.Res__110960Galaxolide and tonalide modulate neuroendocrine activity in marine species from two taxonomic groups
El Jellas_2021_J.Clin.Endocrinol.Metab__Two new mutations in the CEL gene causing diabetes and hereditary pancreatitis: How to correctly identify MODY8 cases
El Kharraf_2021_Molecules_26_Simultaneous Hydrodistillation-Steam Distillation of Rosmarinus officinalis, Lavandula angustifolia and Citrus aurantium from Morocco, Major Terpenes: Impact on Biological Activities
El Khatabi_2021_J.Mol.Model_27_302Identification of novel acetylcholinesterase inhibitors through 3D-QSAR, molecular docking, and molecular dynamics simulation targeting Alzheimer's disease
El Khatabi_2021_Turk.J.Chem_45_647Integrated 3D-QSAR, molecular docking, and molecular dynamics simulation studies on 1,2,3-triazole based derivatives for designing new acetylcholinesterase inhibitors
El Yaagoubi_2021_J.Ethnopharmacol__114205A review on Moroccan Thymus species: traditional uses, essential oils chemical composition and biological effects
El-Ganainy_2021_Nanomedicine.(Lond)__Galantamine nanoparticles outperform oral galantamine in an Alzheimer's rat model: pharmacokinetics and pharmacodynamics
El-Hawwary_2021_RSC.Adv_11_18009Green-synthesized zinc oxide nanoparticles, anti-Alzheimer potential and the metabolic profiling of Sabal blackburniana grown in Egypt supported by molecular modelling
El-Koofy_2021_Lipids.Health.Dis_20_38Management strategy and novel ophthalmological findings in neonatal severe hypertriglyceridemia: a case report and literature review
El-Malek_2021_Front.Bioeng.Biotechnol_9_817023Post-Synthetic Enzymatic and Chemical Modifications for Novel Sustainable Polyesters
El-Nashar_2021_Molecules_26_GC/MS Analysis of Essential Oil and Enzyme Inhibitory Activities of Syzygium cumini (Pamposia) Grown in Egypt: Chemical Characterization and Molecular Docking Studies
El-Sarnagawy_2021_Cardiovasc.Toxicol__Validation of Corrected and Dispersed QT as Predictors of Adverse Outcomes in Acute Cardiotoxicities
El-Sayad_2021_Acta.Parasitol__microRNA-155 Expression and Butyrylcholinesterase Activity in the Liver Tissue of Mice Infected with Toxoplasma gondii (Avirulent and Virulent Strains)
ElDin_2021_Biosens.Bioelectron_190_113439Microfabricated potentiometric sensor for personalized methacholine challenge tests during the COVID-19 pandemic
El_2021_ACS.Omega_6_20492Phenolic Profiling and Therapeutic Potential of Certain Isolated Compounds from Parkia roxburghii against AChE Activity as well as GABA(A) alpha5, GSK-3beta, and p38alpha MAP-Kinase Genes
El_2021_Environ.Sci.Pollut.Res.Int__Assessment of the marine ecotoxic state in the Moroccan coastal area Anza-Taghazout following the installation of two wastewater treatment plants: a multibiomarker study using Mytilus galloprovincialis
Elfiky_2021_J.Crohns.Colitis__Carboxylesterase-1 assisted targeting of HDAC inhibitors to mononuclear myeloid cells in Inflammatory Bowel Disease
Elgueta_2021_Toxics_9_Analysis of Multi-Pesticide Residues and Dietary Risk Assessment in Fresh Tomatoes (Lycopersicum esculentum) from Local Supermarkets of the Metropolitan Region, Chile
Elhachimi_2021_Ticks.Tick.Borne.Dis_13_101883Variation of diazinon and amitraz susceptibility of Hyalomma marginatum (Acari: Ixodidae) in the Rabat-Sale-Kenitra region of Morocco
Elias_2021_EMBO.Rep_22_e53256Dan Salah Tawfik (1955-2021) A giant of protein evolution
Elmorsy_2021_Heliyon_7_e06269The protective effect of Indian Catechu methanolic extract against aluminum chloride-induced neurotoxicity, A rodent model of Alzheimer's disease
Elshafie_2021_Plants.(Basel)_10_Study of Bio-Pharmaceutical and Antimicrobial Properties of Pomegranate (Punica granatum L.) Leathery Exocarp Extract
Elshamy_2021_J.Food.Biochem__e13644Potential neuroprotective activity of Mentha longifolia L. in aluminum chloride-induced rat model of Alzheimer's disease
Elshony_2021_Front.Neurosci_15_651471Ameliorative Role of Cerium Oxide Nanoparticles Against Fipronil Impact on Brain Function, Oxidative Stress, and Apoptotic Cascades in Albino Rats
Emam_2021_Molecules_26_Phytochemical Profiling of Lavandula coronopifolia Poir. Aerial Parts Extract and Its Larvicidal, Antibacterial, and Antibiofilm Activity Against Pseudomonas aeruginosa
Emerson_2021_G3.(Bethesda)__Acetylcholine Signaling Genes are Required for Cocaine-Stimulated Egg Laying in Caenorhabditis elegans
Emori_2021_Proteins_89_502Structural basis of mutants of PET-degrading enzyme from Saccharomonospora viridis AHK190 with high activity and thermal stability
Endo_2021_Am.J.Emerg.Med__Cholinergic crisis caused by ingesting topical carpronium chloride solution: A case report
Engler_2021_Drugs.Today.(Barc)_57_607Evinacumab to treat hypercholesterolemia
English_2021_Sci.Rep_11_2914Neonicotinoid pesticides exert metabolic effects on avian pollinators
Eom_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109142Exposure to metals premixed with microplastics increases toxicity through bioconcentration and impairs antioxidant defense and cholinergic response in a marine mysid
Epstein_2021_BMC.Pulm.Med_21_1MiR-608 overexpression in idiopathic pulmonary fibrosis (IPF)
Epstein_2021_Toxicol.Lett__Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR
Erban_2021_J.Proteomics_249_104356Label-free proteomic analysis reveals differentially expressed Wolbachia proteins in Tyrophagus putrescentiae: Mite allergens and markers reflecting population-related proteome differences
Erdogan_2021_Arch.Pharm.(Weinheim)__e2000409Synthesis and docking calculations of tetrafluoronaphthalene derivatives and their inhibition profiles against some metabolic enzymes
Erdogan_2021_Arch.Pharm.(Weinheim)__e2100113Synthesis and biological evaluation of some 1-naphthol derivatives as antioxidants, acetylcholinesterase, and carbonic anhydrase inhibitors
Eroglu_2021_Noro.Psikiyatr.Ars_58_166Atypical Neuroleptic Malignant Syndrome Induced by Low Dose Quetiapine in a Patient Treated with Donepezil
Ertas_2021_Chem.Biodivers__Phytochemical fingerprints and bioactivities of Ripe Disseminules (Fruit-Seeds) of seventeen Gundelia (Kenger-kereng dikeni) Species from Anatolia with Chemometric Approach
Erukainure_2021_Amino.Acids_53_1135L-leucine stimulation of glucose uptake and utilization involves modulation of glucose - lipid metabolic switch and improved bioenergetic homeostasis in isolated rat psoas muscle ex vivo
Erukainure_2021_Amino.Acids_53_359Oxidative testicular injury: effect of L-leucine on redox, cholinergic and purinergic dysfunctions, and dysregulated metabolic pathways
Erukainure_2021_Andrologia__e14175Strawberry fruit (Fragaria x ananassa Romina) juice attenuates oxidative imbalance with concomitant modulation of metabolic indices linked to male infertility in testicular oxidative injury
Erukainure_2021_Endocr.Metab.Immune.Disord.Drug.Targets_21_688Cola Nitida (Kola Nuts) Attenuates Hepatic Injury in Type 2 Diabetes by Improving Antioxidant and Cholinergic Dysfunctions and Dysregulated Lipid Metabolism
Erukainure_2021_Food.Chem.Toxicol_154_112335Cola nitida infusion modulates cardiometabolic activities linked to cardiomyopathy in diabetic rats
Erukainure_2021_Front.Pharmacol_12_610835Turbina oblongata Protects Against Oxidative Cardiotoxicity by Suppressing Lipid Dysmetabolism and Modulating Cardiometabolic Activities Linked to Cardiac Dysfunctions
Esang_2021_Cureus_13_e17591Aducanumab as a Novel Treatment for Alzheimer's Disease: A Decade of Hope, Controversies, and the Future
Esfandi_2021_J.Food.Biochem__e13762Antioxidant, pancreatic lipase, and alpha-amylase inhibitory properties of oat bran hydrolyzed proteins and peptides
Esmaeilnejad_2021_Trop.Anim.Health.Prod_53_219Assessment of hepatic oxidative damage, paraoxonase-1 activity, and lipid profile in cattle naturally infected with Ba7besia bigemina
Estevez_2021_Chem.Biol.Interact__109764Interactions of human acetylcholinesterase with phenyl valerate and acetylthiocholine: Thiocholine as an enhancer of phenyl valerate esterase activity
Estrada-Valenzuela_2021_Pharmaceuticals.(Basel)_14_Lipase Assisted (S)-Ketoprofen Resolution from Commercially Available Racemic Mixture
Evangelista_2021_J.Enzyme.Inhib.Med.Chem_36_1659Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
Ewen_2021_Life.Sci__119129A review on advances of treatment modalities for Alzheimer's disease
Ezgu_2021_Expert.Opin.Drug.Saf__Safety of sebelipase alfa for the treatment of lysosomal acid lipase deficiency
Fabbri_2021_Int.J.Mol.Sci_22_Biocatalyzed Synthesis of Flavor Esters and Polyesters: A Design of Experiments (DoE) Approach
Fabiani_2021_Mol.Pharmacol__New synthetic caffeine analogs as modulators of the cholinergic system
Fabrello_2021_Mar.Environ.Res_165_105247Effects of a mixture of glyphosate, 17alpha-ethynylestradiol and amyl salicylate on cellular and biochemical parameters of the mussel Mytilus galloprovincialis
Fabritius_2021_J.Clin.Med_10_Bi-Centric Independent Validation of Outcome Prediction after Radioembolization of Primary and Secondary Liver Cancer
Fais_2021_Plants.(Basel)_10_Euphorbia characias: Phytochemistry and Biological Activities
Fakhar_2021_J.Biomol.Struct.Dyn__1Discovery of novel heterocyclic amide-based inhibitors: an integrative in-silico approach to targeting soluble epoxide hydrolase
Fakhereddin_2021_Arh.Hig.Rada.Toksikol_72_164Pro-oxidant potency of clothianidin in rainbow trout
Falfushynska_2021_Water.Res_194_116923Multibiomarker-based assessment of toxicity of central European strains of filamentous cyanobacteria Aphanizomenon gracile and Raphidiopsis raciborskii to zebrafish Danio rerio
Fan_2021_Chemosphere_288_132491Mechanistic insights into primary biotransformation of diethyl phthalate in earthworm and significant SOD inhibitory effect of esterolytic products
Fan_2021_Foods_10_Accelerated Solvent Extraction of Antioxidant Compounds from Gardeniae Fructus and Its Acetylcholinesterase Inhibitory and PC12 Cell Protective Activities
Fan_2021_Gigascience_10_A chromosome-level genome of the spider Trichonephila antipodiana reveals the genetic basis of its polyphagy and evidence of an ancient whole-genome duplication event
Fan_2021_J.Alzheimers.Dis__The Efficacy and Safety of Alzheimer's Disease Therapies: An Updated Umbrella Review
Fan_2021_J.Ethnopharmacol__114572Acer truncatum Bunge: A comprehensive review on ethnobotany, phytochemistry and pharmacology
Fan_2021_Pest.Manag.Sci__Effects of elevated CO(2) on activities of protective and detoxifying enzymes in Frankliniella occidentalis and Frankliniella intonsa under spinetoram stress1
Fan_2021_Structure__Interplay between hevin, SPARC, and MDGAs: modulators of neurexin-neuroligin transsynaptic bridges
Fang_2021_Drug.Metab.Dispos__Role of epoxide hydrolases and cytochrome P450s on metabolism of KZR-616, a first-in-class selective inhibitor of the immunoproteasome
Fang_2021_Int.J.Pharm__120399Repurposing of Camptothecin: An Esterase-Activatable Prodrug Delivered by a Self-Emulsifying Formulation that Improves Efficacy in Colorectal Cancer
Fang_2021_J.Med.Entomol__Molecular Analysis of Targeted Insecticide Resistance Gene Mutations in Field-Caught Mosquitos of Medical Importance From Saudi Arabia
Fang_2021_Sci.Total.Environ_796_149051Enantioselective bioaccumulation and detoxification mechanisms of earthworms (Eisenia fetida) exposed to mandipropamid
Farag_2021_Neurochem.Res__Metabolomic Profiling and Neuroprotective Effects of Purslane Seeds Extract Against Acrylamide Toxicity in Rat's Brain
Farah_2021_Biochem.Biophys.Res.Commun_591_311-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1
Faraone_2021_Phytochemistry_187_112781Screening of in vitro and in silico alpha-amylase, alpha-glucosidase, and lipase inhibitory activity of oxyprenylated natural compounds and semisynthetic derivatives
Faria_2021_Sci.Total.Environ_775_145671Androgenic activation, impairment of the monoaminergic system and altered behavior in zebrafish larvae exposed to environmental concentrations of fenitrothion
Farooq_2021_Curr.Genet__Molecular characterization of lipase from a psychrotrophic bacterium Pseudomonas sp. CRBC14
Farouk_2021_Biomed.Pharmacother_138_111458Exploring the possible neuroprotective and antioxidant potency of lycopene against acrylamide-induced neurotoxicity in rats' brain
Faruk_2021_J.Neurochem__Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning
Fathi_2021_Iran.J.Microbiol_13_871Partial purification, characterization and immobilization of a novel lipase from a native isolate of Lactobacillus fermentum
Fatiha_2021_Mol.Inform__Identification of 1,2,4-triazolylthioethanone Scaffold for the Design of New Acetylcholinesterase Inhibitors
Fawzi_2021_Food.Res.Int_140_110068A comprehensive evaluation of the chemical profiles and biological properties of six geophytes from Turkey: Sources of bioactive compounds for novel nutraceuticals
Feghhi_2021_Breast.Cancer.Res.Treat__Bystander effects induced by electron beam-irradiated MCF-7 cells: a potential mechanism of therapy resistance
Felix_2021_Pharmaceuticals.(Basel)_14_Chemical Composition, Larvicidal Activity, and Enzyme Inhibition of the Essential Oil of Lippia grata Schauer from the Caatinga Biome against Dengue Vectors
Feng_2021_Foods_10_Fabrication of Nano/Micro-Structured Electrospun Detection Card for the Detection of Pesticide Residues
Feng_2021_J.Hazard.Mater_417_125983Bioremediation of triphenyl phosphate by Pycnoporus sanguineus: Metabolic pathway, proteomic mechanism and biotoxicity assessment
Feng_2021_Mikrochim.Acta_188_280SERS-ELISA determination of human carboxylesterase 1 using metal-organic framework doped with gold nanoparticles as SERS substrate
Fernandes_2021_Chem.Biol.Interact__109431Exposure to lutein-loaded nanoparticles attenuates Parkinson's model-induced damage in Drosophila melanogaster: restoration of dopaminergic and cholinergic system and oxidative stress indicators
Fernandez-Galleguillos_2021_Metabolites_11_UHPLC-MS Chemical Fingerprinting and Antioxidant, Antiproliferative, and Enzyme Inhibition Potential of Gaultheria pumila Berries
Fernandez-Penas_2021_Cryst.Growth.Des_21_1698Production of Cross-Linked Lipase Crystals at a Preparative Scale
Ferraz_2021_Int.J.Environ.Res.Public.Health_18_Melanin: Production from Cheese Bacteria, Chemical Characterization, and Biological Activities
Ferreira_2021_Eur.J.Med.Chem_221_113492Dual-target compounds for Alzheimer's disease: Natural and synthetic AChE and BACE-1 dual-inhibitors and their structure-activity relationship (SAR)
Ferreira_2021_Neurotox.Res_39_327Effect of Proline on Cell Death, Cell Cycle, and Oxidative Stress in C6 Glioma Cell Line
Ferreira_2021_Xenobiotica__1Polymorphisms in xenobiotic metabolism-related genes in patients with hepatocellular carcinoma: a case-control study
Fersht_2021_J.Mol.Biol_433_167088AlphaFold - A Personal Perspective on the Impact of Machine Learning
Filip_2021_Cell.Chem.Biol_28_202Profiling of MicroRNA Targets Using Activity-Based Protein Profiling: Linking Enzyme Activity to MicroRNA-185 Function
Filippi_2021_Heliyon_7_e07921Validation of exposure indexes to pesticides through the analysis of exposure and effect biomarkers in ground pesticide applicators from Argentina
Fiorilli_2021_Methods.Mol.Biol_2309_75Evaluation of the Effect of Strigolactones and Synthetic Analogs on Fungi
Firdaus_2021_Mini.Rev.Med.Chem_21_35An Insight in Pathophysiological Mechanism of Alzheimer's Disease and its Management Using Plant Natural Products
Fisayo_2021_Food.Chem.X_12_100165Identification and characterization of cholesterol esterase and lipase inhibitory peptides from amaranth protein hydrolysates
Fitzgerald_2021_Behav.Brain.Res__113323Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test
Fitzgerald_2021_Int.J.Mol.Sci_22_Norepinephrine May Oppose Other Neuromodulators to Impact Alzheimer's Disease
Flanagan_2021_Nature__NOTUM from Apc-mutant cells biases clonal competition to initiate cancer
Floris_2021_J.Enzyme.Inhib.Med.Chem_36_517Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and alpha-amylase and alpha-glucosidase activity
Foladi_2021_Radiol.Case.Rep_16_2857CT features of Wolman disease (lysosomal acid lipase enzyme deficiency) - A case report
Fontes_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109198Environmentally realistic concentrations of cocaine in seawater disturbed neuroendrocrine parameters and energy status in the marine mussel Perna perna
Foo_2021_Methods.Mol.Biol_2309_179Application of Strigolactones to Plant Roots to Influence Formation of Symbioses
Forcada_2021_PLoS.One_16_e0259939A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats
Forte_2021_J.Occup.Health_63_e12222Pesticide exposure and adverse health effects associated with farmwork in Northern Thailand
Fowler_2021_J.Intern.Med_290_2The endocannabinoid system - current implications for drug development
Franca_2021_Nat.Prod.Res__1Chemical composition, in vitro cytotoxic and anticholinesterase activities of flower extracts of Senna spectabilis var. excelsa and Senna macranthera
Francis_2021_Nat.Prod.Res__1Clathriketal, a new tricyclic spiroketal compound from marine sponge Clathria prolifera attenuates serine exopeptidase dipeptidyl peptidase-IV
Frangiamore_2021_Neurol.Sci__Iatrogenic Kaposi's sarcoma in myasthenia gravis: learnings from two case reports
Fras_2021_Arch.Med.Sci_17_954On the present and future role of Lp-PLA(2) in atherosclerosis-related cardiovascular risk prediction and management
Freed_2021_Am.J.Med.Genet.A_185_827CHRNB1-associated congenital myasthenia syndrome: Expanding the clinical spectrum
Frei_2021_eNeuro__Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism
Fridjonsdottir_2021_ACS.Chem.Biol__Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems
Friedli_2021_Molecules_26_Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer's Disease
Fronza_2021_ACS.Chem.Neurosci_12_109Effect of QTC-4-MeOBnE Treatment on Memory, Neurodegeneration, and Neurogenesis in a Streptozotocin-Induced Mouse Model of Alzheimer's Disease
Fronza_2021_Brain.Behav.Immun__Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: the role of blood-brain barrier permeability, NF-kB signaling, and microglial activation
Frota_2021_J.Biomol.Struct.Dyn__1Antioxidant and anticholinesterase activities of amentoflavone isolated from Ouratea fieldingiana (Gardner) Engl. through in vitro and chemical-quantum studies
Fu_2021_ACS.Appl.Bio.Mater_4_3539Oxidase-like Nanozyme-Mediated Altering of the Aspect Ratio of Gold Nanorods for Breaking through H(2)O(2)-Supported Multicolor Colorimetric Assay: Application in the Detection of Acetylcholinesterase Activity and Its Inhibitors
Fu_2021_J.Pharm.Biomed.Anal_204_114266An activatable chemiluminescence probe based on phenoxy-dioxetane scaffold for biothiol imaging in living systems
Fu_2021_Sci.Total.Environ_813_152617Behaviors and biochemical responses of macroinvertebrate Corbicula fluminea to polystyrene microplastics
Fuchs_2021_Hepatology__Hepatocyte-specific deletion of adipose triglyceride lipase (ATGL/PNPLA2) ameliorates dietary induced steatohepatitis in mice
Fuhr_2021_Pharmaceutics_13_270Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug-Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach
Fukushi_2021_Clin.Exp.Nephrol__Butyrylcholinesterase level as an independent prognostic factor for overall survival in patients on maintenance hemodialysis: a single-center retrospective study
Fuller_2021_Environ.Pollut_291_118217Enhanced trophic transfer of chlorpyrifos from resistant Hyalella azteca to inland silversides (Menidia beryllina) and effects on acetylcholinesterase activity and swimming performance at varying temperatures
Furtado_2021_Mol.Neurobiol_58_4615JM-20 Treatment After Mild Traumatic Brain Injury Reduces Glial Cell Pro-inflammatory Signaling and Behavioral and Cognitive Deficits by Increasing Neurotrophin Expression
Fuzita_2021_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110670A proteomic approach to identify digestive enzymes, their exocytic and microapocrine secretory routes and their compartmentalization in the midgut of Spodoptera frugiperda
Gabriel_2021_Biotechnol.Biofuels_14_169CAZymes from the thermophilic fungus Thermoascus aurantiacus are induced by C5 and C6 sugars
Gabriele_2021_Life.Sci__119486Carboxylesterases and arylacetamide deacetylase comparison in human A549, H460, and H727 pulmonary cells
Gad_2021_Plants.(Basel)_10_GC-MS Based Identification of the Volatile Components of Six Astragalus Species from Uzbekistan and Their Biological Activity
Gago-Dominguez_2021_Sci.Rep_11_10436LIPG endothelial lipase and breast cancer risk by subtypes
Gajjar_2021_Curr.Drug.Discov.Technol__Structure-Based De Novo Design and Docking Studies of 5(S)-Methyl-L-Proline Containing Peptidomimetic Compounds as Dipeptidyl Peptidase-4 Inhibitors
Galili_2021_Plants.(Basel)_10_Characterization of a Chickpea Mutant Resistant to Phelipanche aegyptiaca Pers. and Orobanche crenata Forsk
Gallego_2021_Chemosphere_271_129399Enzymatic activity changes in striped catfish Pseudoplatystoma magdaleniatum, induced by exposure to different concentrations of ibuprofen and triclosan
Gallego_2021_Environ.Pollut_275_116647Ecotoxicological impact of the antihypertensive valsartan on earthworms, extracellular enzymes and soil bacterial communities
Gambarini_2021_mSystems_6_Phylogenetic Distribution of Plastic-Degrading Microorganisms
Gamblin_2021_Diabetes_70_76Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy
Gan_2021_Exp.Ther.Med_21_425Kuwanon G protects HT22 cells from advanced glycation end product-induced damage
Ganesh_2021_Neurology_97_964Editors' Note: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Ganeshpurkar_2021_J.Biomol.Struct.Dyn__1Development of homology model, docking protocol and Machine-Learning based scoring functions for identification of Equus caballus's butyrylcholinesterase inhibitors
Ganeshpurkar_2021_Mol.Divers__Improved machine learning scoring functions for identification of Electrophorus electricus's acetylcholinesterase inhibitors
Gangaram_2021_Plants.(Basel)_11_Phytochemicals and Biological Activities of Barleria (Acanthaceae)
Gao_2021_Ann.Transl.Med_9_1339A novel method of subxiphoid video-assisted thoracic surgery for thymectomy
Gao_2021_Bioorg.Chem_114_105149Pharmacophore-based drug design of AChE and BChE dual inhibitors as potential anti-Alzheimer's disease agents
Gao_2021_Clin.Lab_67_The Role of Cholinesterase in Differential Diagnosis between Gastric Cancer and Benign Gastric Diseases
Gao_2021_Enzyme.Microb.Technol_150_109868Recent advances in the discovery, characterization, and engineering of poly(ethylene terephthalate) (PET) hydrolases
Gao_2021_Int.J.Mol.Sci_22_Design and Synthesis of Ranitidine Analogs as Multi-Target Directed Ligands for the Treatment of Alzheimer's Disease
Gao_2021_J.Am.Chem.Soc_143_80A Polyketide Cyclase That Forms Medium-Ring Lactones
Gao_2021_J.Biotechnol_325_280Identification of a GDSL lipase from Streptomyces bacillaris and its application in the preparation of free astaxanthin
Gao_2021_Mol.Plant.Microbe.Interact__MPMI08200235RThe Role of Clt1-Regulated Xylan Metabolism in Melanin and Toxin Formation for the Pathogenicity of Curvularia lunata in Maize
Gao_2021_Nat.Microbiol__A natural symbiotic bacterium drives mosquito refractoriness to Plasmodium infection via secretion of an antimalarial lipase
Gao_2021_World.J.Microbiol.Biotechnol_37_106Improving the catalytic efficiency and substrate affinity of a novel esterase from marine Klebsiella aerogenes by random and site-directed mutation
Garcia-Morales_2021_Biomedicines_9_Current Understanding of the Physiopathology, Diagnosis and Therapeutic Approach to Alzheimer's Disease
Gareri_2021_Rev.Recent.Clin.Trials__An Overview of Combination Treatment with Citicoline in Dementia
Garlet_2021_Environ.Entomol__Fitness Cost of Chlorpyrifos Resistance in Spodoptera frugiperda (Lepidoptera: Noctuidae) on Different Host Plants
Garlet_2021_Pest.Manag.Sci__Field-evolved resistance to chlorpyrifos by Spodoptera frugiperda (Lepidoptera: Noctuidae): inheritance mode, cross-resistance patterns, and synergism
Garmyn_2021_J.Wildl.Dis__Persecution of Birds of Prey in Flanders: A Retrospective Study 2011-19
Gatford_2021_Hum.Mol.Genet__Neuroligin-3 and Neuroligin-4X form Nanoscopic clusters and regulate growth cone organization and size
Gautheron_2021_Elife_10_EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence
Gavini_2021_Brain.Res.Bull__Developmental nicotine exposure impairs memory and reduces acetylcholine levels in the hippocampus of mice
Gavril_2021_Medicina.(Kaunas)_57_1153Role of PNPLA3 in the Assessment and Monitoring of Hepatic Steatosis and Fibrosis in Patients with Chronic Hepatitis C Infection Who Achieved a Sustained Virologic Response
Gavril_2021_Medicina.(Kaunas)_57_1249Correlations between PNPLA3 Gene Polymorphisms and NAFLD in Type 2 Diabetic Patients
Gawarecka_2021_Plant.Cell.Environ__cis-Prenyltransferase 3 and alpha/beta-hydrolase are new determinants of dolichol accumulation in Arabidopsis
Gayathri_2021_CNS.Neurol.Disord.Drug.Targets__Phytotherapeutics Against Alzheimer's Disease: Mechanism, Molecular Targets and Challenges for Drug Development
Gaytan_2021_Appl.Microbiol.Biotechnol_105_991Current status on the biodegradability of acrylic polymers: microorganisms, enzymes and metabolic pathways involved
Gbadamosi_2021_Sci.Total.Environ_771_144752A critical review of human exposure to organophosphate esters with a focus on dietary intake
Gbenga-Fabusiwa_2021_J.Food.Biochem__e13658Modulatory effect of pigeon pea-wheat biscuits on lipid profile, lipid peroxidation level, alpha-glucosidase, and butyrylcholinesterase activities in type-2 diabetic patients
Ge_2021_Life.Sci__119268Short-term standard alcohol consumption enhances platelet response to clopidogrel through inhibition of Nrf2/Ces1 pathway and induction of Cyp2c in mice
Geethu_2021_Protein.J_40_669Improved 3-D Protein Structure Predictions using Deep ResNet Model
Geng_2021_Front.Nutr_8_790520Nutritional Status and Body Composition in Wilson Disease: A Cross-Sectional Study From China
Gentzsch_2021_ChemMedChem__Synthesis and Initial Characterization of a Selective, Pseudo-irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer
Gentzsch_2021_Mol.Imaging.Biol__Synthesis and Initial Characterization of a Reversible, Selective (18)F-Labeled Radiotracer for Human Butyrylcholinesterase
Georgiou_2021_J.Biomol.Struct.Dyn__1Structure assignment, conformational properties and discovery of potential targets of the Ugi cinnamic adduct NGI25
Gerlits_2021_Curr.Res.Struct.Biol_3_206Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure
Geula_2021_J.Neurochem__Basal forebrain cholinergic system in the dementias: Vulnerability, resilience, and resistance
Ghafour-Boroujerdi_2021_Life.Sci__119766Investigation of alpha-lipoic acid effect on memory impairment considering strain-dependent differences in mice
Gherbovet_2021_Beilstein.J.Org.Chem_17_325Regioselective chemoenzymatic syntheses of ferulate conjugates as chromogenic substrates for feruloyl esterases
Ghiam_2021_Front.Neurosci_15_635483Drug Repurposing in the Treatment of Traumatic Brain Injury
Ghimire_2021_Arch.Microbiol__Complete genome sequencing and comparative CAZyme analysis of Rhodococcus sp. PAMC28705 and PAMC28707 provide insight into their biotechnological and phytopathogenic potential
Ghodke_2021_Environ.Microbiol__Environmental role of aromatic carboxylesterases
Ghofrani_2021_Daru__Immobilization of Candida rugosa lipase for resolution of racimic ibuprofen
Gholivand_2021_Mol.Divers__Synthesis, crystal structure, cholinesterase inhibitory activity, evaluation of insecticidal activities, and computational studies of new phosphonic acids
Gholivand_2021_Mol.Divers__2Monophosphoramide derivatives: synthesis and crystal structure, theoretical and experimental studies of their biological effects
Ghosh_2021_Front.Mol.Neurosci_14_678510Cannabinoid Signaling in Auditory Function and Development
Gianessi_2021_Eur.J.Neurosci__The effects of fatty acid amide hydrolase inhibition and monacylglycerol lipase inhibition on habit formation in mice
Giese_2021_Bioconjug.Chem__Linker Architectures as Steric Auxiliaries for Altering Enzyme-Mediated Payload Release from Bioconjugates
Glucklich_2021_Eur.J.Pharm.Sci__105980Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions
Godfrey_2021_Brain.Res__147518Enzymes of acetylcholine metabolism in the rat inferior colliculus
Godoy_2021_Front.Physiol_12_643281An Overview of Antennal Esterases in Lepidoptera
Godyn_2021_Bioorg.Chem_114_105129Cyanobiphenyls: Novel H(3) receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease
Goger_2021_Turk.J.Chem_45_387Phytochemical characterisation of Phlomis linearis Boiss. & Bal and screening for anticholinesterase, antiamylase, antimicrobial, and cytotoxic properties
Gogoi_2021_J.Food.Biochem__e13767Chemical composition of Callistemon citrinus (Curtis) Skeels aerial part essential oil and its pharmacological applications, neurodegenerative inhibitory, and genotoxic efficiencies
Gok_2021_Arch.Pharm.(Weinheim)__e2000496Synthesis of novel sulfonamides with anti-Alzheimer and antioxidant capacities
Gok_2021_Food.Chem_368_130775Profiling the annual change of the neurobiological and antioxidant effects of five Origanum species in correlation with their phytochemical composition
Gomaa_2021_Fundam.Clin.Pharmacol_35_97Evaluation of the neuroprotective effect of donepezil in type 2 diabetic rats
Goncalves_2021_Curr.Top.Med.Chem__2',6'-dihydroxy-4'-methoxy dihydrochalcone improves the cognitive impairment of Alzheimer's disease: a structure-activity relationship study
Goncalves_2021_Eur.J.Pharmacol__174089Endogenous opioid and cannabinoid systems modulate the muscle pain: a pharmacological study into the peripheral site
Goncalves_2021_Molecules_26_Impact of Metallic Nanoparticles on In Vitro Culture, Phenolic Profile and Biological Activity of Two Mediterranean Lamiaceae Species: Lavandula viridis L'Her and Thymus lotocephalus G. Lopez and R. Morales
Gong_2021_Bioengineered_12_5241Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma
Gong_2021_Insect.Sci__Molecular and functional characterization of three novel carboxylesterases in the detoxification of permethrin in the mosquito, Culex quinquefasciatus
Gong_2021_Mol.Divers__A novel artificial intelligence protocol to investigate potential leads for diabetes mellitus
Gonzalez-Barrio_2021_Parasit.Vectors_14_488Changes in serum biomarkers of inflammation in bovine besnoitiosis
Gonzalez-Morales_2021_J.Med.Entomol__Resistance to Fipronil in the Common Bed Bug (Hemiptera: Cimicidae)
Gonzalez_2021_Curr.Res.Toxicol_2_341Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats
Gopi_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109161Interactive effects of freshwater acidification and selenium pollution on biochemical changes and neurotoxicity in Oreochromis mossambicus
Gordon_2021_Exp.Neurol__113717Peripheral nerves preferentially regenerate in intramuscular endoneurial tubes to reinnervate denervated skeletal muscles
Gorecki_2021_ACS.Chem.Neurosci__Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease
Gorecki_2021_Arch.Toxicol__Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
Gorecki_2021_Eur.J.Med.Chem_219_113434Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors
Gorelik_2021_Sci.Adv_7_eabf4155Structure of the murine lysosomal multienzyme complex core
Gori_2021_Top.Curr.Chem.(Cham)_379_33Organic-Molecule-Based Fluorescent Chemosensor for Nerve Agents and Organophosphorus Pesticides
Goryainova_2021_Crystallogr.Rep_66_811Three-Dimensional Structure of Single-Point Mutant of Esterase PMGL2
Gorzi_2021_Mol.Neurobiol__Training Intensity, Not Duration, May Be Key to Upregulating Presynaptic Proteins of Calcium Dynamics and Calcium-Dependent Exocytosis in Fast- and Slow-Twitch Skeletal Muscles, in Addition to Maintaining Performance After Detraining
Gowayed_2021_BMC.Pharmacol.Toxicol_22_24The effective interplay of (non-) selective NSAIDs with neostigmine in animal models of analgesia and inflammation
Gowler_2021_Arthritis.Rheumatol__Clinical and preclinical evidence for roles of soluble epoxide hydrolase in osteoarthritis knee pain
Gozutok_2021_Brain.Sci_11_Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS
Graf_2021_J.Pharm.Sci__Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation
Graf_2021_Methods.Enzymol_648_337Structural analysis of PET-degrading enzymes PETase and MHETase from Ideonella sakaiensis
Graikou_2021_Planta.Med__Chemical Characterisation-Biological Evaluation of Greek Cultivar Cardoon Seeds (Cynara cardunculus). A By-product with Potential High Added Value
Grajales-Hernandez_2021_Appl.Microbiol.Biotechnol__Approaches for the enzymatic synthesis of alkyl hydroxycinnamates and applications thereof
Granada_2021_PLoS.Negl.Trop.Dis_15_e0010001Molecular surveillance of resistance to pyrethroids insecticides in Colombian Aedes aegypti populations
Grau-Bove_2021_PLoS.Genet_17_e1009253Resistance to pirimiphos-methyl in West African Anopheles is spreading via duplication and introgression of the Ace1 locus
Gravato_2021_Methods.Mol.Biol_2240_119Acetylcholinesterase (AChE) Activity in Embryos of Zebrafish
Gravdal_2021_J.Biol.Chem_296_100661The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity
Grcic_2021_Environ.Pollut_288_117706Sensitivity of midgut physiological parameters of Lymantria dispar L. larvae to benzo[a]pyrene in populations with different multigeneration contact to environmental pollutants
Greene_2021_Biomacromolecules_22_19993D-Printed Enzyme-Embedded Plastics
Greene_2021_J.Emerg.Med_60_197Monocled Cobra (Naja kaouthia) Envenomations Requiring Mechanical Ventilation
Grevengoed_2021_J.Clin.Invest_131_An abundant biliary metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides
Griffin_2021_Cells_10_Integrated Action of Autophagy and Adipose Tissue Triglyceride Lipase Ameliorates Diet-Induced Hepatic Steatosis in Liver-Specific PLIN2 Knockout Mice
Grigorev_2021_Mol.Inform__Structural Fractal Analysis of the Active Site of Acetylcholinesterase in Complexes with Huperzine A, Galantamine, and Donepezil
Grinan-Ferre_2021_Int.J.Mol.Sci_22_Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease
Grininger_2021_Biomolecules_11_1299Structural Changes in the Cap of Rv0183/mtbMGL Modulate the Shape of the Binding Pocket
Grodner_2021_Int.J.Mol.Sci_23_In Vitro and In Silico Kinetic Studies of Patented 1,7-diEthyl and 1,7-diMethyl Aminoalkanol Derivatives as New Inhibitors of Acetylcholinesterase
Grott_2021_Sci.Total.Environ_771_144971Influence of temperature on biomarker responses and histology of the liver of American bullfrog tadpoles (Lithobates catesbeianus, Shaw, 1802) exposed to the herbicide Tebuthiuron
Gruber-Dorninger_2021_Toxins.(Basel)_13_Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme
Gu_2021_Ann.Palliat.Med_10_12566Sugammadex enhances recovery after abdominal surgery in cancer patients: a real-world, observational study
Gu_2021_Int.J.Biol.Macromol_171_382Characteristics of a recombinant Fusarium verticillioides cutinase and its effects on enzymatic hydrolysis of rice straw
Gu_2021_J.Gene.Med__e3403Silencing of circDPP4 suppresses cell progression of human prostate cancer and enhances docetaxel cytotoxicity through regulating miR-564/ZIC2 axis
Guan_2021_Bioorg.Med.Chem.Lett__128306Design, synthesis, and cholinesterase inhibition assay of liquiritigenin derivatives as anti-Alzheimer's activity
Guan_2021_Front.Bioeng.Biotechnol_9_806788Biochemical and Structural Characterization of a Novel Bacterial Tannase From Lachnospiraceae bacterium in Ruminant Gastrointestinal Tract
Guan_2021_Insect.Sci_28_627Whole-genome sequencing to detect mutations associated with resistance to insecticides and Bt proteins in Spodoptera frugiperda
Guan_2021_Int.J.Mol.Sci_22_Epoxyeicosatrienoic Acids and Fibrosis: Recent Insights for the Novel Therapeutic Strategies
Guan_2021_Talanta_225_121948Fluorometric probe for the lipase level: Design, mechanism and biological imaging application
Guenther_2021_Eur.J.Anaesthesiol_38_554Low cholinesterase activity is a risk factor for delirium after cardiac surgery: A prospective cohort study
Guerra_2021_Arch.Environ.Contam.Toxicol__Biochemical and Behavioral Responses in Zebrafish Exposed to Imidacloprid Oxidative Damage and Antioxidant Responses
Guillory_2021_Methods.Mol.Biol_2309_143Methods for Medium-Scale Study of Biological Effects of Strigolactone-Like Molecules on the Moss Physcomitrium (Physcomitrella) patens
Guillory_2021_Plant.Mol.Biol__Phytohormone biosynthesis and signaling pathways of mosses
Guimaraes_2021_Aquat.Toxicol_233_105795Can carbon nanofibers affect anurofauna? Study involving neotropical Physalaemus cuvieri (Fitzinger, 1826) tadpoles
Guimaraes_2021_J.Hazard.Mater_403_123864Nanopolystyrene particles at environmentally relevant concentrations causes behavioral and biochemical changes in juvenile grass carp (Ctenopharyngodon idella)
Guimaraes_2021_Sci.Total.Environ_779_146514Multiple toxicity endpoints induced by carbon nanofibers in Amazon turtle juveniles: Outspreading warns about toxicological risks to reptiles
Gul_2021_Acta.Neurol.Belg_121_529Congenital myasthenic syndrome in Turkey: clinical and genetic features in the long-term follow-up of patients
Gulcan_2021_Curr.Top.Med.Chem_21_2752Dual monoamine oxidase and cholinesterase Inhibitors with different heterocyclic scaffolds
Gulcan_2021_Curr.Top.Med.Chem__The hybrid compounds as multi-target ligands for the treatment of Alzheimer's Disease: Considerations on Donepezil
Guller_2021_Altern.Ther.Health.Med_27_33Radical Scavenging and Antiacetylcholinesterase Activities of Ethanolic Extracts of Carob, Clove, and Linden
Gumus_2021_Arch.Pharm.(Weinheim)__e2100242Discovery of sulfadrug-pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors
Gunay_2021_Semin.Cell.Dev.Biol_112_92Importance of lipids for upper motor neuron health and disease
Gunderson_2021_Toxicol.Sci__Neuroligin-1 is a mediator of methylmercury neuromuscular toxicity
Gundlach_2021_Sci.Total.Environ_792_148368Effects of the antidepressant mirtazapine on the swimming behaviour and gene expression rate of Danio rerio embryos - Is the sedating effect seen in humans also evident for fish?
Gunsel_2021_J.Biomol.Struct.Dyn__1Novel tetrakis-phthalocyanines bearing pyrimidine derivative: crystal XRD analysis, enzyme inhibition, molecular docking, and anticancer effects
Guo_2021_Anal.Bioanal.Chem_413_5835Desorption electrospray ionization (DESI) source coupling ion mobility mass spectrometry for imaging fluoropezil (DC20) distribution in rat brain
Guo_2021_Anal.Chem__Multienzyme-Targeted Fluorescent Probe as a Biosensing Platform for Broad Detection of Pesticide Residues
Guo_2021_Bioengineered_12_7600Preparation of MED1(transcription mediator subunit) gene nanocarrier and its mechanism of action on liver cell regeneration in chronic acute liver failure
Guo_2021_Biomater.Sci__The facile formation of hierarchical mesoporous silica nanocarriers for tumor-selective multimodal theranostics
Guo_2021_Chemosphere_263_128270iTRAQ and PRM-based comparative proteomic profiling in gills of white shrimp Litopenaeus vannamei under copper stress
Guo_2021_Food.Res.Int_148_110587Complexation of caffeine and theophylline with epigallocatechin gallate in aqueous solution: Nuclear magnetic resonance, molecular docking and thermodynamics studies
Guo_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1174_122722A strategy to discover selective alpha-glucosidase/acetylcholinesterase inhibitors from five function-similar citrus herbs through LC-Q-TOF-MS, bioassay and virtual screening
Guo_2021_J.Trace.Elem.Med.Biol_68_126844Protective effects of pretreatment with Fe(2+), Cu(2+), and Rb(+) on phoxim poisoning in silkworm, Bombyx mori
Guo_2021_Microorganisms_9_Characterization of Two Unique Cold-Active Lipases Derived from a Novel Deep-Sea Cold Seep Bacterium
Guo_2021_Nat.Prod.Res__1Total synthesis of (-)-brazilane via a lipase-catalyzed desymmetrisation reaction
Guo_2021_Open.Biol_11_210106ANGPTL8 in metabolic homeostasis: more friend than foe?
Guo_2021_Sci.Rep_11_16409NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice
Guo_2021_Sci.Rep_11_18744Acute benzo[a]pyrene exposure induced oxidative stress, neurotoxicity and epigenetic change in blood clam Tegillarca granosa
Guo_2021_Sci.Rep_11_5428Bioinformatis analysis reveals possible molecular mechanism of PXR on regulating ulcerative colitis
Guo_2021_Sci.Total.Environ_789_147887Combined toxicity of micro/nano scale polystyrene plastics and ciprofloxacin to Corbicula fluminea in freshwater sediments
Guo_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_266_120412Determination of methomyl in grain using deep eutectic solvent-based extraction combined with fluorescence-based enzyme inhibition assays
Gupta_2021_Biochem.J__Rivastigmine attenuates the Alzheimer's disease related protein degradation and apoptotic neuronal death signaling
Gurdere_2021_In.Silico.Pharmacol_9_34ADME properties, bioactivity and molecular docking studies of 4-amino-chalcone derivatives: new analogues for the treatment of Alzheimer, glaucoma and epileptic diseases
Gurunathan_2021_Int.J.Nanomedicine_16_2849Palladium Nanoparticle-Induced Oxidative Stress, Endoplasmic Reticulum Stress, Apoptosis, and Immunomodulation Enhance the Biogenesis and Release of Exosome in Human Leukemia Monocytic Cells (THP-1)
Gurunathan_2021_Int.J.Nanomedicine_16_515Platinum Nanoparticles Enhance Exosome Release in Human Lung Epithelial Adenocarcinoma Cancer Cells (A549): Oxidative Stress and the Ceramide Pathway are Key Players
Gutbrod_2021_Phytochemistry_185_112684Fatty acid isoprenoid alcohol ester synthesis in fruits of the African Oil Palm (Elaeis guineensis)
Guzel_2021_J.Biochem.Mol.Toxicol__e22765Biologically active phthalocyanine metal complexes: Preparation, evaluation of alpha-glycosidase and anticholinesterase enzyme inhibition activities, and molecular docking studies
Gwozdzinski_2021_Cardiol.Res.Pract_2021_5569961Alterations in the Plasma and Red Blood Cell Properties in Patients with Varicose Vein: A Pilot Study
Ha_2021_Curr.Alzheimer.Res__Synthesis, Molecular Docking, and Biological Evaluation of Benzimidazole Derivatives as Selective Butyrylcholinesterase Inhibitors
Habib_2021_Food.Chem_364_130415Inhibitory effects of honey from arid land on some enzymes and protein damage
Hachisuka_2021_Appl.Environ.Microbiol__AEM0002021Development of a targeted gene disruption system in the PET-degrading bacterium Ideonella sakaiensis and its applications to PETase and MHETase genes
Hacioglu_2021_Biol.Trace.Elem.Res_199_3793Effects of Curcumin and Boric Acid Against Neurodegenerative Damage Induced by Amyloid Beta (1-42)
Hadda_2021_Med.Chem_17_834Spiro Heterocyclic Compounds as Potential Anti-Alzheimer Agents (Part 2): Their Metal Chelation Capacity, POM Analyses and DFT Studies
Hafez_2021_Mar.Drugs_19_Marine-Derived Compounds with Anti-Alzheimer's Disease Activities
Hafez_2021_Mol.Cell.Biochem__Ameliorative effects of astaxanthin on brain tissues of alzheimer's disease-like model: cross talk between neuronal-specific microRNA-124 and related pathways
Hagen_2021_PLoS.Pathog_17_e1009286Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis
Haghighijoo_2021_Eur.J.Med.Chem_227_113949Therapeutic potential of quinazoline derivatives for Alzheimer's disease: A comprehensive review
Hagiwara-Nagasawa_2021_Naunyn.Schmiedebergs.Arch.Pharmacol_394_581Analysis of electropharmacological and proarrhythmic effects of donepezil using the halothane-anesthetized intact dogs and the conscious chronic atrioventricular block ones
Hajlaoui_2021_Molecules_26_Antimicrobial, Antioxidant, Anti-Acetylcholinesterase, Antidiabetic, and Pharmacokinetic Properties of Carum carvi L. and Coriandrum sativum L. Essential Oils Alone and in Combination
Hake_2021_Planta.Med__Alkaloids from Lime Flower (Tiliae flos) Exert Spasmodic Activity on Murine Airway Smooth Muscle Involving Acetylcholinesterase
Halder_2021_Front.Immunol_12_660342Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Halff_2021_Behav.Brain.Res__113203Effects of chronic exposure to haloperidol, olanzapine or lithium on SV2A and NLGN synaptic puncta in the rat frontal cortex
Halminen_2021_J.Alzheimers.Dis__Early Start of Anti-Dementia Medication Delays Transition to 24-Hour Care in Alzheimer's Disease Patients: A Finnish Nationwide Cohort Study
Hamdan_2021_Appl.Microbiol.Biotechnol__Thermostable lipases and their dynamics of improved enzymatic properties
Hamdeh_2021_Aliment.Pharmacol.Ther__Review article: drug-induced small bowel injury
Hameleers_2021_Biotechnol.Biofuels_14_127Polysaccharide utilization loci-driven enzyme discovery reveals BD-FAE: a bifunctional feruloyl and acetyl xylan esterase active on complex natural xylans
Hamiaux_2021_Methods.Mol.Biol_2309_233The Use of Differential Scanning Fluorimetry to Assess Strigolactone Receptor Function
Hamidi_2021_Environ.Sci.Pollut.Res.Int__Effect of petroleum wastewater treated with gravity separation and magnetite nanoparticles adsorption methods on the blood biochemical response of mrigal fish (Cirrhinus cirrhosus)
Hammid_2021_Mol.Pharm__Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues
Hammock_2021_J.Med.Chem__Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative
Hamoudi_2021_Comb.Chem.High.Throughput.Screen__Phytochemical screening, in vitro antioxidant and enzyme inhibitory proprieties and acute toxicity of extracts from the aerial parts of Ephedra nebrodensis, source of bioactive compounds
Hamulakova_2021_Future.Med.Chem__Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease
Han_2021_Acc.Chem.Res__Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer's Disease
Han_2021_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1866_158988Lipolysis and lipophagy play individual and interactive roles in regulating triacylglycerol and cholesterol homeostasis and mitochondrial form in zebrafish
Han_2021_Biotechnol.Lett__Surface charge engineering of Thermomyces lanuginosus lipase improves enzymatic activity and biodiesel synthesis
Han_2021_Diabetes.Obes.Metab_23_682Effectiveness and safety of sodium-glucose co-transporter-2 inhibitors compared with dipeptidyl peptidase-4 inhibitors in older adults with type 2 diabetes: A nationwide population-based study
Han_2021_Environ.Health.Perspect_129_77004A Roadmap to the Structure-Related Metabolism Pathways of Per- and Polyfluoroalkyl Substances in the Early Life Stages of Zebrafish (Danio rerio)
Han_2021_J.Asian.Nat.Prod.Res__1Citrinin and alpha-pyrone derivatives with pancreatic lipase inhibitory activities from Penicillium sp. SCSIO 41302
Han_2021_Mar.Drugs_19_Mixture of Phlorotannin and Fucoidan from Ecklonia cava Prevents the Abeta-Induced Cognitive Decline with Mitochondrial and Cholinergic Activation
Han_2021_Toxicol.Res_37_443No prominent toxicity of polyethylene microplastics observed in neonatal mice following intratracheal instillation to dams during gestational and neonatal period
Handl_2021_Chem.Res.Toxicol__Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening
Hansen_2021_Thorax__Organophosphate and carbamate insecticide exposure is related to lung function change among smallholder farmers: a prospective study
Hanslik_2021_Sci.Total.Environ__151640Rethinking the relevance of microplastics as vector for anthropogenic contaminants: Adsorption of toxicants to microplastics during exposure in a highly polluted stream - Analytical quantification and assessment of toxic effects in zebrafish (Danio rerio)
Hao_2021_J.Med.Entomol__Transcriptome Analysis of Aedes albopictus (Diptera: Culicidae) Larvae Exposed With a Sublethal Dose of Haedoxan A
Hapeta_2021_Sci.Rep_11_6412A 37-amino acid loop in the Yarrowia lipolytica hexokinase impacts its activity and affinity and modulates gene expression
Harada_2021_Appl.Microbiol.Biotechnol__Carboxylesterases for the hydrolysis of acetoacetate esters and their applications in terpenoid production using Escherichia coli
Haris_2021_Acc.Chem.Res__Seeking Illumination: The Path to Chemiluminescent 1,2-Dioxetanes for Quantitative Measurements and In Vivo Imaging
Harthern-Flint_2021_Front.Microbiol_12_670928Experimental and Genomic Evaluation of the Oestrogen Degrading Bacterium Rhodococcus equi ATCC13557
Hartmann_2021_J.Med.Chem_64_2815Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH/PPARgamma Modulator
Hartz_2021_J.Biotechnol__Development and application of a highly efficient CRISPR-Cas9 system for genome engineering in Bacillus megaterium
Hasan_2021_Bioorg.Chem_119_105572Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics simulation
Hashem_2021_Mol.Neurobiol__Inhibition of 2-Arachidonoylglycerol Metabolism Alleviates Neuropathology and Improves Cognitive Function in a Tau Mouse Model of Alzheimer's Disease
Hashemi_2021_Am.J.Med.Genet.A_185_440Clinical spectrum in multiple families with primary COQ(10) deficiency
Hassan_2021_Afr.Health.Sci_21_1124Insecticide resistance of Dengue vectors in South East Asia: a systematic review
Hassan_2021_Mol.Divers__New organosulfur metallic compounds as potent drugs: synthesis, molecular modeling, spectral, antimicrobial, drug likeness and DFT analysis
Hassan_2021_Pak.J.Pharm.Sci_34_47Neuroprotective and antioxidant effect of Curcuma longa (Rhizome) methanolic extract on SH-SY5Y cells and Javanese medaka
Hassan_2021_Phytomedicine_93_153771Health benefits and phenolic compounds of Moringa oleifera leaves: A comprehensive review
Hassanzadeh_2021_Res.Pharm.Sci_16_482Design, synthesis, and bio-evaluation of new isoindoline-1,3-dione derivatives as possible inhibitors of acetylcholinesterase
Hatori_2021_Anticancer.Res_41_3583Clinical Significance of PLA2G2A Expression in Gastric Cancer Patients who Receive Gastrectomy and Adjuvant S-1
Hauser-Davis_2021_Ecotoxicol.Environ.Saf_208_111589Biochemical metal accumulation effects and metalloprotein metal detoxification in environmentally exposed tropical Perna perna mussels
Hawkey_2021_Neurotoxicol.Teratol__106985Neurobehavioral anomalies in zebrafish after sequential exposures to DDT and chlorpyrifos in adulthood: Do multiple exposures interact?
Hayes_2021_Chem.Res.Toxicol_34_63Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats
Hayes_2021_Curr.Pharm.Des__Bioactive peptides in preventative healthcare: An overview of bioactivities and suggested methods to assess potential applications
He_2021_Anal.Chem__Bifunctional Moderator-Powered Ratiometric Electrochemiluminescence Enzymatic Biosensors for Detecting Organophosphorus Pesticides Based on Dual-Signal Combined Nanoprobes
He_2021_Bioprocess.Biosyst.Eng__High specific immobilization of His-tagged recombinant Microbacterium esterase by Ni-NTA magnetic chitosan microspheres for efficient synthesis of key chiral intermediate of d-biotin
He_2021_Cell.Death.Dis_12_992Deletion of soluble epoxide hydrolase suppressed chronic kidney disease-related vascular calcification by restoring Sirtuin 3 expression
He_2021_Chirality__Resolution of (R,S)-1-(4-methoxyphenyl)ethanol by lipase-catalyzed stereoselective transesterification and the process optimization
He_2021_Environ.Pollut_287_117649Toxicity of gabapentin-lactam on the early developmental stage of zebrafish (Danio rerio)
He_2021_Environ.Res_203_111902The relationship between pesticide exposure during critical neurodevelopment and autism spectrum disorder: A narrative review
He_2021_Free.Radic.Biol.Med_178_369Mitochondrial homeostasis and redox status in cardiovascular diseases: Protective role of the vagal system
He_2021_Int.J.Med.Mushrooms_23_71Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycota), Attenuates Abeta1-42-Induced Amyloidogenesis and Inflammatory Response by Suppressing Amyloid Precursor Protein Progression and p38 MAPK/JNK Activation
He_2021_J.Mater.Chem.B__Near-infrared fluorescent probe for evaluating the acetylcholinesterase effect in the aging process and dietary restriction via fluorescence imaging
He_2021_Nucl.Med.Biol_96-97_S36Development of reversible monoacylglycerol lipase PET tracers with improved brain uptake
Hegde_2021_Genomics.Inform_19_e44Genetic analysis of the postsynaptic transmembrane X-linked neuroligin 3 gene in autism
Heier_2021_Elife_10_Hormone-sensitive lipase couples intergenerational sterol metabolism to reproductive success
Heinrich_2021_J.Gerontol.A.Biol.Sci.Med.Sci_76_1029Radiological, Chemical, and Pharmacological Cholinergic System Parameters and Neurocognitive Disorders in Older Presurgical Adults
Heise_2021_Eur.J.Med.Chem_227_113947N-methylated diazabicyclo[3.2.2]nonane substituted triterpenoic acids are excellent, hyperbolic and selective inhibitors for butyrylcholinesterase
Helal_2021_J.Genet.Eng.Biotechnol_19_1Lipase from Rhizopus oryzae R1: in-depth characterization, immobilization, and evaluation in biodiesel production
Helderman_2021_Bone__115946Loss of Function of Lysosomal Acid Lipase (LAL) Profoundly Impacts Osteoblastogenesis and Increases Fracture Risk in Humans
Hemaida_2021_ACS.Omega_6_19202Synthesis and Biological Evaluation of Thiazole-Based Derivatives as Potential Acetylcholinesterase Inhibitors
Her_2021_Br.J.Clin.Pharmacol__Effect of CES1 genetic variation on enalapril steady-state pharmacokinetics and pharmacodynamics in healthy subjects
Herceg_2021_Mar.Pollut.Bull_170_112654Fatty acids, persistent organic pollutants, and trace elements in small pelagic fish from the eastern Mediterranean Sea
Hermansyah_2021_Comput.Biol.Chem_95_107597Virtual screening of dipeptidyl peptidase-4 inhibitors using quantitative structure-activity relationship-based artificial intelligence and molecular docking of hit compounds
Hernandez-Toledano_2021_Chem.Biol.Interact_346_109578The cytoskeleton as a non-cholinergic target of organophosphate compounds
Herr_2021_Drugs.Aging__Removal of Drugs for Alzheimer's Disease from the List of Reimbursable Drugs in France: Analysis of Change in Drug Use, Disease Management and Cognition Using the National Alzheimer Data Bank (BNA)
Herrera-Acevedo_2021_Mol.Divers__Machine learning models to select potential inhibitors of acetylcholinesterase activity from SistematX: a natural products database
Herrera-Moreno_2021_Environ.Sci.Pollut.Res.Int__Organophosphorus pesticide exposure biomarkers in a Mexican population
Herrera_2021_Prim.Care.Diabetes_15_323Cardiovascular events and mortality among type 2 diabetes mellitus patients newly prescribed first-line blood glucose-lowering drugs monotherapies: A population-based cohort study in the Catalan electronic medical record database, SIDIAP, 2010-2015
Herriage_2021_Toxicol.In.Vitro_78_105268Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells
Hetrick_2021_ACS.Chem.Biol__Endogenous Enzymes Enable Antimicrobial Activity
Hewage_2021_Org.Lett__An Enzyme-Mediated Aza-Michael Addition Is Involved in the Biosynthesis of an Imidazoyl Hybrid Product of Conidiogenone B
Heyde_2021_Microb.Cell.Fact_20_93Surface display as a functional screening platform for detecting enzymes active on PET
Hilliou_2021_Insects_12_Resistance in the Genus Spodoptera: Key Insect Detoxification Genes
Hinkaew_2021_Molecules_26_A Comparison of the Nutritional and Biochemical Quality of Date Palm Fruits Obtained Using Different Planting Techniques
Hinkovska-Galcheva_2021_J.Lipid.Res_62_100089Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis
Hirasawa_2021_J.Nat.Med__Cliniatines A-C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase
Hirata_2021_Mol.Biol.Cell__mbcE20070500Atg15 in Saccharomyces cerevisiae consists of two functionally distinct domains
Hiremathad_2021_Chem.Biodivers__Multi-Targeting Tacrine Conjugates with Cholinesterase and Amyloid-Beta Inhibitory Activities: New Anti-Alzheimer's Agents
Hirosawa_2021_Drug.Metab.Dispos__Role of human AADAC on hydrolysis of eslicarbazepine acetate and effects of AADAC genetic polymorphisms on hydrolase activity
Ho-Plagaro_2021_New.Phytol_229_548DLK2 regulates arbuscule hyphal branching during arbuscular mycorrhizal symbiosis
Hofmann_2021_Chemistry_27_6015Azobioisosteres of Curcumin with Pronounced Activity against Amyloid Aggregation, Intracellular Oxidative Stress, and Neuroinflammation
Hollenbach_2021_Adv.Biochem.Eng.Biotechnol__Parameters Influencing Lipase-Catalyzed Glycolipid Synthesis by (Trans-)Esterification Reaction
Hollingsworth_2021_Nature__DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
Holmes_2021_Genetics__A novel allele in the Arabidopsis thaliana MACPF protein CAD1 results in deregulated immune signaling
Honda_2021_Biochimie__The involvement of Nile tilapia (Oreochromis niloticus) Neu4 sialidase in neural differentiation during early ontogenesis
Honda_2021_Drug.Metab.Dispos__Differences in hydrolase activities in the liver and small intestine between marmosets and humans
Honda_2021_Eur.J.Pharm.Sci__105807Hydrolase activities of cynomolgus monkey liver microsomes and recombinant CES1, CES2, and AADAC
Hong_2021_Br.J.Clin.Pharmacol_87_2757Pharmacokinetics and safety of evogliptin in hepatically impaired patients
Hong_2021_Cancer.Gene.Ther_28_27LIPG: an inflammation and cancer modulator
Honorio_2021_Chem.Biol.Interact__109523Binding interaction of protoberberine alkaloids against acetylcholinesterase (AChE) using molecular dynamics simulations and QM/MM calculations
Hoppner_2021_FEBS.J_288_3570Crystal structures of a novel family IV esterase in free and substrate-bound form
Horn_2021_Front.Microbiol_12_804935Corynebacterium Species Inhibit Streptococcus pneumoniae Colonization and Infection of the Mouse Airway
Hosokawa_2021_Nat.Neurosci__CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation
Hossain_2021_Heliyon_7_e08285Heavy metal toxicity in Buriganga river alters the immunology of Nile tilapia (Oreochromis niloticus L)
Hou_2021_Enzyme.Microb.Technol_150_109859Expression of an alkaline feruloyl esterases from thermophilic Chaetomium thermophilum and its boosting effect on delignification of pulp
Hou_2021_Exp.Mol.Pathol_121_104658Overexpression of serum lncRNA-ABHD11-AS1 as poor prognosis of patients with papillary thyroid carcinoma
Hou_2021_J.Med.Chem_64_123Positron Emission Tomography Imaging of the Endocannabinoid System: Opportunities and Challenges in Radiotracer Development
Hou_2021_Materials.(Basel)_14_Potential for and Distribution of Enzymatic Biodegradation of Polystyrene by Environmental Microorganisms
Hroudova_2021_Mol.Neurobiol_58_1102Effects of Novel Tacrine Derivatives on Mitochondrial Energy Metabolism and Monoamine Oxidase Activity-In Vitro Study
Hryhorowicz_2021_Front.Immunol_12_790803Endocannabinoid System as a Promising Therapeutic Target in Inflammatory Bowel Disease - A Systematic Review
Hsiao_2021_Mayo.Clin.Proc_96_350The Association Between the Use of Cholinesterase Inhibitors and Cardiovascular Events Among Older Patients With Alzheimer Disease
Hsu_2021_Diabetes.Metab.Syndr.Obes_14_3997Association of Metabolic Syndrome with Aerobic Exercise and LPL rs3779788 Polymorphism in Taiwan Biobank Individuals
Hu_2021_Am.J.Physiol.Heart.Circ.Physiol__Soluble Epoxide Hydrolase Deletion Attenuated Nicotine-induced Arterial Stiffness via Limiting the Loss of SIRT1
Hu_2021_Front.Plant.Sci_12_747160Identification of Conserved and Divergent Strigolactone Receptors in Sugarcane Reveals a Key Residue Crucial for Plant Branching Control
Hu_2021_Int.J.Biol.Macromol_169_1Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity
Hu_2021_J.Appl.Toxicol_41_1345Changes of embryonic development, locomotor activity, and metabolomics in zebrafish co-exposed to chlorpyrifos and deltamethrin
Hu_2021_J.Chem.Inf.Model__Degradation of a Main Plastic Pollutant Polyethylene Terephthalate by Two Distinct Proteases (Neprilysin and Cutinase-like Enzyme)
Hu_2021_J.Clin.Neurosci_91_159Association of EPHX1 polymorphisms with plasma concentration of carbamazepine in epileptic patients: Systematic review and meta-analysis
Hu_2021_Microb.Pathog__104969MicroRNA-146a inhibits autophagy to maintain the intracellular survival of Burkholderia pseudomallei by targeting LIPA
Hu_2021_Nat.Prod.Res__1Indole diketopiperazine alkaloids and aromatic polyketides from the Antarctic fungus Penicillium sp. SCSIO 05705
Hu_2021_New.Phytol__Phytophthora infestans Ago1-associated miRNA promotes potato late blight disease
Hu_2021_Phytopathology_111_1166Hormetic Effects of Dimethachlone on Mycelial Growth and Virulence of Sclerotinia sclerotiorum
Hu_2021_Plant.Biotechnol.J__Repressed OsMESL expression triggers reactive oxygen species mediated broad-spectrum disease resistance in rice
Hu_2021_Sci.Rep_11_21639Explainable machine learning model for predicting spontaneous bacterial peritonitis in cirrhotic patients with ascites
Hu_2021_Thorac.Cardiovasc.Surg__Diagnostic Value of Cholinesterase Activity for Postoperative Delirium
Huang_2021_Adv.Exp.Med.Biol_1303_107Roles of Genetic Predisposition in the Sex Bias of Pulmonary Pathophysiology, as a Function of Estrogens : Sex Matters in the Prevalence of Lung Diseases
Huang_2021_Analyst__Single-cell-resolved measurement of enzyme activity at the tissue level using drop-on-demand microkits
Huang_2021_Cancers.(Basel)_13_DPP9: Comprehensive In Silico Analyses of Loss of Function Gene Variants and Associated Gene Expression Signatures in Human Hepatocellular Carcinoma
Huang_2021_Cells_10_Multi-Target Effects of Novel Synthetic Coumarin Derivatives Protecting Abeta-GFP SH-SY5Y Cells against Abeta Toxicity
Huang_2021_J.Hazard.Mater_421_126830Micro/nano-plastics cause neurobehavioral toxicity in discus fish (Symphysodon aequifasciatus): Insight from brain-gut-microbiota axis
Huang_2021_J.Inflamm.Res_14_6735Antioxidant and Anti-inflammatory Properties Mediate the Neuroprotective Effects of Hydro-ethanolic Extract of Tiliacora triandra Against Cisplatin-induced Neurotoxicity
Huang_2021_J.Sep.Sci__Fast analysis of alkaloids from different parts of Mahonia bealei (Fort.) Carr studied for their anti-Alzheimer's activity using supercritical fluid chromatography
Huang_2021_Mikrochim.Acta_188_318Integrating target-responsive CD-CdTe QD-based ratiometric fluorescence hydrogel with smartphone for visual and on-site determination of dichlorvos
Huang_2021_Nature__Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Huang_2021_Nutr.Metab.Cardiovasc.Dis_31_681ABHD15 promotes cell viability, glycolysis, and inhibits apoptosis in cardiomyocytes under hypoxia
Huang_2021_Sci.Total.Environ__152107Accelerated biodegradation of polyethylene terephthalate by Thermobifida fusca cutinase mediated by Stenotrophomonas pavanii
Huang_2021_Toxins.(Basel)_13_Isolation and Insecticidal Activity of Essential Oil from Artemisia lavandulaefolia DC. against Plutella xylostella
Hudacova_2021_Int.J.Mol.Sci_22_Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells
Hughes_2021_PLoS.One_16_e0258134Pesticides use and health impacts on farmers in Thailand, Vietnam, and Lao PDR: Protocol for a survey of knowledge, behaviours and blood acetyl cholinesterase concentrations
Hull_2021_Curr.Opin.Plant.Biol_62_102071Conditioning plants for arbuscular mycorrhizal symbiosis through DWARF14-LIKE signalling
Hung_2021_Chem.Biodivers__Lantana camara L. essential oils from Vietnam: Chemical composition, molluscicidal, and mosquito larvicidal activity
Hussain_2021_Molecules_26_Neuroprotective Potential of Synthetic Mono-Carbonyl Curcumin Analogs Assessed by Molecular Docking Studies
Hwang_2021_Nutrients_13_Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches
Hye_2021_Br.J.Pharmacol_178_4468Multitarget molecule,PTUPB, to treat diabetic nephropathy in rats
Ibi_2021_Atherosclerosis__Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile
Ibrahim_2021_Biomarkers__1Quercetin ameliorates the hepatic apoptosis of fetal rats induced by in utero exposure to fenitrothion via the transcriptional regulation of paraoxonase-1 and apoptosis-related genes
Ibrahim_2021_Drug.Dev.Res_82_562Macrocyclic sulfone derivatives: Synthesis, characterization, in vitro biological evaluation and molecular docking
Ibrahim_2021_Life.Sci_290_120265Resveratrol alleviates cardiac apoptosis following exposure to fenitrothion by modulating the sirtuin1/c-Jun N-terminal kinases/p53 pathway through pro-oxidant and inflammatory response improvements: In vivo and in silico studies
Ibrahim_2021_Neurochem.Res__Neuroprotective Potential of Berberine Against Doxorubicin-Induced Toxicity in Rat's Brain
Ibrahim_2021_Neuropharmacol__108738Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways
Ibrahim_2021_Vet.World_14_515Polymorphisms in hormone-sensitive lipase and leptin receptor genes and their association with growth traits in Barki lambs
Iddir_2021_Food.Funct_12_9043Gastric lipase can significantly increase lipolysis and carotenoid bioaccessibility from plant food matrices in the harmonized INFOGEST static in vitro digestion model
Idowu_2021_Acta.Trop__106291Multiple insecticide resistance mechanisms in urban population of Anopheles coluzzii (Diptera: Culicidae) from Lagos, South-West Nigeria
Iermak_2021_Catalysts_11_5Description of Transport Tunnel in Haloalkane Dehalogenase Variant LinB D147C+L177C from Sphingobium japonicum
Iijima_2021_Pediatr.Neonatol__Clinical and pathophysiologic relevance of autoantibodies in neonatal myasthenia gravis
Ikeda_2021_J.Med.Chem__Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety
Ikeda_2021_World.J.Biol.Chem_12_104Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagon-like peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer's disease
Ilesanmi_2021_J.Ethnopharmacol__114592Neuroprotective flavonoids of the leaf of Antiaris africana Englea against cyanide toxicity
Ilic_2021_Int.J.Mol.Sci_22_Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts
Ilijin_2021_An.Acad.Bras.Cienc_93_e20190118Biological effects of chronic exposure of Blaptica dubia (Blattodea: Blaberidae) nymphs to static and extremely low frequency magnetic fields
Ilijin_2021_J.Therm.Biol_96_102836Tissue-specific responses of Lymantria dispar L. (Lepidoptera: Erebidae) larvae from unpolluted and polluted forests to thermal stress
Ilyas_2021_Sci.Rep_11_1708Effect of Berberis vulgaris L. root extract on ifosfamide-induced in vivo toxicity and in vitro cytotoxicity
Imangaliyeva_2021_Carbohydr.Polym_273_118601The polyaminosaccharide-based buffers as a new type of zwitterionic buffering macromolecules for biochemical applications
Imig_2021_Biochem.Pharmacol_195_114866Epoxylipids and soluble epoxide hydrolase in heart diseases
Imran_2021_Saudi.J.Biol.Sci_28_3031In vitro examination of anti-parasitic, anti-Alzheimer, insecticidal and cytotoxic potential of Ajuga bracteosa Wallich leaves extracts
Inak_2021_Exp.Appl.Acarol__Geographical distribution and origin of acetylcholinesterase mutations conferring acaricide resistance in Tetranychus urticae populations from Turkey
Inak_2021_Pest.Manag.Sci__Population structure and insecticide resistance status of Tuta absoluta populations from Turkey
Ingenbosch_2021_J.Org.Chem__Effect of Organic Solvents on the Structure and Activity of a Minimal Lipase
Innocenzi_2021_J.Funct.Morphol.Kinesiol_6_Aerobic Exercise Induces Alternative Splicing of Neurexins in Frontal Cortex
Innok_2021_J.Comput.Aided.Mol.Des__In silico and in vitro anti-AChE activity investigations of constituents from Mytragyna speciosa for Alzheimer's disease treatment
Ip_2021_Eur.J.Med.Chem_226_113827A tacrine-tetrahydroquinoline heterodimer potently inhibits acetylcholinesterase activity and enhances neurotransmission in mice
Iqbal_2021_Cells_10_Exploring the Binding Pattern of Geraniol with Acetylcholinesterase through In Silico Docking, Molecular Dynamics Simulation, and In Vitro Enzyme Inhibition Kinetics Studies
Iqubal_2021_Curr.Drug.Targets_22_685Current Quest in Natural Bioactive Compounds for Alzheimer's Disease: Multi-Targeted-Designed-Ligand Based Approach with Preclinical and Clinical Based Evidence
Ishak_2021_PLoS.One_16_e0251751Structure elucidation and docking analysis of 5M mutant of T1 lipase Geobacillus zalihae
Ishimota_2021_Environ.Sci.Pollut.Res.Int__Possible enzymatic mechanism underlying chemical tolerance and characteristics of tolerant population in Scapholeberis kingi
Ishola_2021_Brain.Res.Bull__Prevention and reversal of ketamine-induced experimental psychosis in mice by the neuroactive flavonoid, hesperidin: the role of oxidative and cholinergic mechanisms
Islam_2021_ACS.Omega_6_31539Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors
Islam_2021_BMC.Complement.Med.Ther_21_204Evaluation of cholinesterase inhibitory and antioxidant activity of Wedelia chinensis and isolation of apigenin as an active compound
Islam_2021_Mar.Environ.Res_164_105249Perfluorooctane sulfonic acid (PFOS) adsorbed to polyethylene microplastics: Accumulation and ecotoxicological effects in the clam Scrobicularia plana
Ismail_2021_Int.J.Biol.Macromol_187_127Temperature-resistant and solvent-tolerant lipases as industrial biocatalysts: Biotechnological approaches and applications
Ismail_2021_Toxics_9_Acute and Cumulative Effects of Repeated Exposure to Chlorpyrifos on the Liver and Kidney Function among Egyptian Adolescents
Ismaili_2021_ACS.Chem.Neurosci__(+/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease
Issac_2021_Life.Sci__119864Oxidative stress induced antioxidant and neurotoxicity demonstrated in vivo zebrafish embryo or larval model and their normalization due to morin showing therapeutic implications
Issotina_2021_Int.Immunopharmacol__108365Acetylcholinesterase inhibition with Pyridostigmine attenuates hypertension and neuroinflammation in the paraventricular nucleus in rat model for Preeclampsia
Issotina_2021_J.Hypertens__Pyridostigmine ameliorates preeclamptic features in pregnant rats by inhibiting tumour necrosis factor-alpha synthetsis and antagonizing tumour necrosis factor-alpha-related effects
Istifli_2021_Molecules_26_2981Chemical Composition, Antioxidant and Enzyme Inhibitory Activities of Onosma bourgaei and Onosma trachytricha and in Silico Molecular Docking Analysis of Dominant Compounds
Ito_2021_Methods.Mol.Biol_2309_25Chemical Synthesis of Triazole-Derived Suppressors of Strigolactone Functions
Izquierdo_2021_Neurotoxicol_82_50C. elegans pharyngeal pumping provides a whole organism bio-assay to investigate anti-cholinesterase intoxication and antidotes
Jabir_2021_Curr.Pharm.Des__Identification of butyrylcholinesterase and monoamine oxidase B targeted ligands and their putative application in Alzheimer's treatment: A computational strategy
Jablonski_2021_Neurotoxicol.Teratol__107058Acute toxicity of methomyl commercial formulation induces morphological and behavioral changes in larval zebrafish (Danio rerio)
Jacob_2021_Diabetes.Obes.Metab_23_910Change in glucose-lowering medication regimens in individuals with type 2 diabetes mellitus during the COVID-19 pandemic in Germany
Jacquet_2021_Int.J.Mol.Sci_22_Enzymatic Decontamination of G-Type, V-Type and Novichok Nerve Agents
Jahangirfard_2021_Vet.Res.Forum_12_333Ethephon causes reproductive malfunction in adult male mice: Histological and biochemical evidence
Jain_2021_Appl.Microbiol.Biotechnol_105_389A novel biosensor for the detection of organophosphorus (OP)-based pesticides using organophosphorus acid anhydrolase (OPAA)-FL variant
Jain_2021_Food.Chem_371_131126Emerging vistas on pesticides detection based on electrochemical biosensors - An update
Jaiswal_2021_ChemMedChem__Anticancer potential of small molecule inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase - A mini-review
Jalili-Baleh_2021_Daru__Chromone-lipoic acid conjugate: Neuroprotective agent having acceptable butyrylcholinesterase inhibition, antioxidant and copper-chelation activities
Jamal_2021_Environ.Sci.Pollut.Res.Int__Molecular docking and dynamics studies of cigarette smoke carcinogens interacting with acetylcholinesterase and butyrylcholinesterase enzymes of the central nervous system
Jamali_2021_J.Smok.Cessat_2021_9975811Galantamine as a Treatment Option for Nicotine Addiction
Jamieson_2021_Int.J.Mol.Sci_22_Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury
Jamora_2021_Neurol.Sci__Acetylcholinesterase inhibitor responsive myasthenia in a Filipino male with X-linked recessive spinal and bulbar muscular atrophy
Jamshidnejad-Tosaramandani_2021_Pharmaceuticals.(Basel)_14_The Potential Effect of Insulin on AChE and Its Interactions with Rivastigmine In Vitro
Jan_2021_Int.J.Nanomedicine_16_443Decrease in Cellular Nanovesicles Concentration in Blood of Athletes More Than 15 Hours After Marathon
Jan_2021_Oxid.Med.Cell.Longev_2021_4786227Plant-Based Synthesis of Zinc Oxide Nanoparticles (ZnO-NPs) Using Aqueous Leaf Extract of Aquilegia pubiflora: Their Antiproliferative Activity against HepG2 Cells Inducing Reactive Oxygen Species and Other In Vitro Properties
Jang_2021_Int.J.Mol.Sci_22_CRISPR-Knockout of CSE Gene Improves Saccharification Efficiency by Reducing Lignin Content in Hybrid Poplar
Jankiewicz_2021_Front.Pharmacol_12_744776Dual sEH/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity
Jaouani_2021_Braz.J.Biol_82_e247035Assessment of carbamazepine acute toxicity in the cockle Cerastoderma edule through chemical, physiological and biochemical tools
Jarzebowski_2021_Elife_10_Impaired spatial learning and suppression of sharp wave ripples by cholinergic activation at the goal location
Jasiecki_2021_Int.J.Mol.Sci_22_Butyrylcholinesterase-Protein Interactions in Human Serum
Jasiecki_2021_Int.J.Mol.Sci_22_2The Role of Butyrylcholinesterase and Iron in the Regulation of Cholinergic Network and Cognitive Dysfunction in Alzheimer's Disease Pathogenesis
Jaumotte_2021_Neurobiol.Dis__105422Ciclesonide activates glucocorticoid signaling in neonatal rat lung but does not trigger adverse effects in the cortex and cerebellum
Javadi_2021_Langmuir__Enzymatic Hydrolysis of Triglycerides at the Water-Oil Interface Studied via Interfacial Rheology Analysis of Lipase Adsorption Layers
Javaid_2021_Curr.Pharm.Des_27_3591Neuroprotective Effects of Ellagic Acid in Alzheimer's Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential
Javed_2021_ACS.Chem.Neurosci__Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer's Disease
Jayaraman_2021_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159064Heparin binding triggers human VLDL remodeling by circulating lipoprotein lipase: Relevance to VLDL functionality in health and disease
Jehle_2021_Int.J.Cardiol_323_243The endocannabinoid 2-arachidonoylglycerol inhibits endothelial function and repair
Jekayinoluwa_2021_Plants.(Basel)_10_Transgenic Expression of dsRNA Targeting the Pentalonia nigronervosa acetylcholinesterase Gene in Banana and Plantain Reduces Aphid Populations
Jenkins_2021_Nurs.Crit.Care__Looking after each other in a crisis-Lessons from Novichok and the parallels with Covid-19
Jeon_2021_ACS.Appl.Mater.Interfaces__Neuroligin-1-Modified Electrodes for Specific Coupling with a Presynaptic Neuronal Membrane
Jeon_2021_Crystals_11_170Purification and Crystallographic Analysis of a Novel Cold-Active Esterase (HaEst1) from Halocynthiibacter arcticus
Jeong_2021_Biosci.Biotechnol.Biochem__Enzymatic transformation products of phloretin as potent anti-adipogenic compounds
Jeong_2021_J.Fungi.(Basel)_7_Potent and Selective Inhibitors of Human Monoamine Oxidase A from an Endogenous Lichen Fungus Diaporthe mahothocarpus
Jeong_2021_J.Microbiol.Biotechnol_31_Increased mRNA stability and expression level of Croceibacter atlanticus lipase gene developed through molecular evolution process
Jeong_2021_Molecules_26_3810Identification and Study of Biomarkers from Novichok-Inhibited Butyrylcholinesterase in Human Plasma
Jerves_2021_ACS.Catal_11_11626Reaction Mechanism of the PET Degrading Enzyme PETase Studied with DFT/MM Molecular Dynamics Simulations
Ji_2021_Br.J.Clin.Pharmacol_87_2247The impact of ABCB1 and CES1 polymorphisms on dabigatran pharmacokinetics and pharmacodynamics in patients with atrial fibrillation
Jia_2021_Front.Chem_9_780304Acorenone C: A New Spiro-Sesquiterpene from a Mangrove-Associated Fungus, Pseudofusicoccum sp. J003
Jia_2021_J.Med.Chem__Directionally Modified Fluorophores for Super-Resolution Imaging of Target Enzymes: A Case Study with Carboxylesterases
Jiang_2021_Adv.Ther__A Clinical and Budgetary Impact Analysis of Introducing Sugammadex for Routine Reversal of Neuromuscular Blockade in a Hypothetical Cohort in the US
Jiang_2021_Antioxidants.(Basel)_10_Identification and Antioxidant Abilities of Enzymatic-Transesterification (-)-Epigallocatechin-3-O-gallate Stearyl Derivatives in Non-Aqueous Systems
Jiang_2021_Appl.Environ.Microbiol__Identification of Detoxification Esterase StrH Initiating Strobilurin Fungicides Degradation in Hyphomicrobium sp. DY-1
Jiang_2021_Arch.Insect.Biochem.Physiol__e21842A role of peptidoglycan recognition protein in mediating insecticide detoxification in Glyphodes pyloalis
Jiang_2021_Eur.J.Med.Chem_223_113663Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE/GSK3beta inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine
Jiang_2021_Eur.J.Med.Chem_223_113735Novel cannabidiol-carbamate hybrids as selective BuChE inhibitors: Docking-based fragment reassembly for the development of potential therapeutic agents against Alzheimer's disease
Jiang_2021_Int.J.Dermatol__Two cases of Chanarin-Dorfman syndrome with novel and recurrent mutations in the ABHD5 gene
Jiang_2021_J.Food.Sci__Structural characterization and antioxidant property of enzymatic-transesterification derivatives of (-)-epigallocatechin-3-O-gallate and vinyl laurate
Jiang_2021_J.Int.Med.Res_49_300060521999527Progesterone activates the cyclic AMP-protein kinase A signalling pathway by upregulating ABHD2 in fertile men
Jiang_2021_Zhonghua.Yi.Xue.Za.Zhi_101_2448[Diagnostic value of combined detection of different indicators for type 2 diabetes mellitus combined with atherosclerotic disease]
Jiao_2021_ACS.Sens__3D-Printed, Portable, Fluorescent-Sensing Platform for Smartphone-Capable Detection of Organophosphorus Residue Using Reaction-Based Aggregation Induced Emission Luminogens
Jiaojiao_2021_J.Sci.Food.Agric_101_3186Lipase nanogel catalyzed synthesis of vitamin E succinate in non-aqueous phase
Jin_2021_ACS.Chem.Biol__The Angiopoietin-Like Protein 3 and 8 Complex Interacts with Lipoprotein Lipase and Induces LPL Cleavage
Jing_2021_Food.Chem_370_131360Application of deep eutectic solvent-based extraction coupled with an S-CQD fluorescent sensor for the determination of pirimicarb in cereals
Joao_2021_ChemMedChem__Homarine alkyl esters derivatives as new promising acetylcholinesterase inhibitors
Johan_2021_Colloids.Surf.B.Biointerfaces_205_111882An integrated overview of bacterial carboxylesterase: Structure, function and biocatalytic applications
Johanif_2021_Environ.Pollut_289_117900Bioaccumulation potential of chlorpyrifos in resistant Hyalella azteca: Implications for evolutionary toxicology
John_2021_Forensic.Sci.Int_323_110818Evidence of exposure to organophosphorus toxicants by detection of the propionylated butyrylcholinesterase-derived nonapeptide-adduct as a novel biomarker
John_2021_J.Mass.Spectrom.Adv.Clin.Lab_19_20Poisoning by organophosphorus nerve agents and pesticides: An overview of the principle strategies and current progress of mass spectrometry-based procedures for verification
Johnson_2021_Biochem.Biophys.Rep_28_101175Biochemical evaluation and molecular docking assessment of Cymbopogon citratus as a natural source of acetylcholine esterase (AChE)- targeting insecticides
Johnson_2021_Toxicol.Rep_8_571Benzo[a]pyrene and Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced locomotor and reproductive senescence and altered biochemical parameters of oxidative damage in Canton-S Drosophila melanogaster
Johnson_2021_Xenobiotica__1Optimal pH 8.5 to 9 for the Hydrolysis of Vixotrigine and Other Basic Substrates of Carboxylesterase-1 in Human Liver Microsomes
Jonczyk_2021_Biomolecules_11_Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase
Jonnalagadda_2021_Int.J.Mol.Sci_22_A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis
Joviano-Santos_2021_FEBS.J__Motoneuron-specific loss of VAChT mimics neuromuscular defects seen in Congenital Myasthenic Syndrome
Ju_2021_Pestic.Biochem.Physiol_178_104925Insecticide resistance in the Cydia pomonella (L): Global status, mechanisms, and research directions
Juban_2021_Haematologica_106_1106Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay
Jumper_2021_Nature_596_583Highly accurate protein structure prediction with AlphaFold
Jumper_2021_Proteins__Applying and improving AlphaFold at CASP14
Jung_2021_J.Biol.Eng_15_9An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases
Junkum_2021_J.Med.Entomol__Enhancement of Temephos and Deltamethrin Toxicity by Petroselinum crispum Oil and its Main Constituents Against Aedes aegypti (Diptera: Culicidae)
Kaabel_2021_Proc.Natl.Acad.Sci.U.S.A_118_Enzymatic depolymerization of highly crystalline polyethylene terephthalate enabled in moist-solid reaction mixtures
Kabuye_2021_Indian.J.Tuberc_68_179Lysosomal acid lipase gene single nucleotide polymorphism and pulmonary tuberculosis susceptibility
Kadir_2021_Bioorg.Chem_113_105032Fatty acid composition, enzyme inhibitory effect, antioxidant and anticancer activity of extract from Saponaria prostrata WILLD. subsp. anatolica HEDGE
Kadokura_2021_J.Nutr.Sci_10_e62Effect of fish paste products, fish balls 'tsumire', intake in Sprague-Dawley rats
Kadowaki_2021_Diabetes.Obes.Metab__A Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adding Omarigliptin to Insulin Therapy in Japanese Patients with Type 2 Diabetes and Inadequate Glycemic Control
Kahlert_2021_Angew.Chem.Int.Ed.Engl_60_11423Biosynthesis of 6-Hydroxymellein Requires a Collaborating Polyketide Synthase-like Enzyme
Kakamad_2021_Int.J.Surg.Case.Rep_85_106149Thymoma with osseous metaplasia; a case report with a brief literature review
Kalita_2021_Mol.Pharm_18_451Synthesis and Screening of alpha-Xylosides in Human Glioblastoma Cells
Kalyandurg_2021_Phytopathology__Spray-induced gene silencing as a potential tool to control potato late blight disease
Kamdi_2021_Cytokine_139_155408Phloridzin attenuates lipopolysaccharide-induced cognitive impairment via antioxidant, anti-inflammatory and neuromodulatory activities
Kamdi_2021_Eur.J.Pharmacol__174645Ameliorative potential of phloridzin in type 2 diabetes-induced memory deficit in rats
Kamecki_2021_Neuropharmacol_201_108837Multitarget 2'-hydroxychalcones as potential drugs for the treatment of neurodegenerative disorders and their comorbidities
Kamei_2021_Patient.Prefer.Adherence_15_2103Effect of Psychoeducational Intervention on Donepezil Retention Rate and Analysis of Reasons for the Discontinuation in Patients with Alzheimer's Dementia: A Randomized Study
Kamnate_2021_J.Anat__In situ localization of diacylglycerol lipase alpha and beta producing an endocannabinoid 2-arachidonoylglycerol and of cannabinoid receptor 1 in the primary oocytes of postnatal mice
Kamoun_2021_Heliyon_7_e06717In vitro lipolysis and physicochemical characterization of unconventional star anise oil towards the development of new lipid-based drug delivery systems
Kan_2021_Chembiochem__IsPETase represents a novel biocatalyst for poly (ethylene terephthalate) (PET) hydrolysis
Kandasamy_2021_Int.J.Biol.Macromol__In silico, theoretical biointerface analysis and in vitro kinetic analysis of amine compounds interaction with acetylcholinesterase and butyrylcholinesterase
Kandeda_2021_Evid.Based.Complement.Alternat.Med_2021_6610864Ziziphus jujuba (Rhamnaceae) Alleviates Working Memory Impairment and Restores Neurochemical Alterations in the Prefrontal Cortex of D-Galactose-Treated Rats
Kandeil_2021_J.Toxicol_2021_4411316Nanonaringenin and Vitamin E Ameliorate Some Behavioral, Biochemical, and Brain Tissue Alterations Induced by Nicotine in Rats
Kandil_2021_Drug.Dev.Ind.Pharm__1Intranasal galantamine/chitosan complex nanoparticles elicit neuroprotection potentials in rat brains via antioxidant effect
Kaneko_2021_Biomark.Res_9_21Serum soluble CD26/DPP4 titer variation is a potential prognostic biomarker in cancer therapy with a humanized anti-CD26 antibody
Kang_2021_ACS.Omega_6_14963Acetylcholine Detection Based on pH-Sensitive Liposomes
Kang_2021_Crit.Rev.Biotechnol__1Liamocins biosynthesis, its regulation in Aureobasidium spp., and their bioactivities
Kang_2021_Environ.Sci.Pollut.Res.Int__Multiple transcriptomic profiling: potential novel metabolism-related genes predict prepubertal testis damage caused by DEHP exposure
Kang_2021_J.Microbiol.Biotechnol_31_51Actinidia arguta Sprout as a Natural Antioxidant: Ameliorating Effect on Lipopolysaccharide-Induced Cognitive Impairment
Kang_2021_Pharmaceutics_13_Co-Spray Dried Nafamostat Mesylate with Lecithin and Mannitol as Respirable Microparticles for Targeted Pulmonary Delivery: Pharmacokinetics and Lung Distribution in Rats
Kang_2021_Pharmaceutics_13_2Subcutaneously Injectable Hyaluronic Acid Hydrogel for Sustained Release of Donepezil with Reduced Initial Burst Release: Effect of Hybridization of Microstructured Lipid Carriers and Albumin
Kaniakova_2021_Biochem.Pharmacol__1144607-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo
Kanojia_2021_CNS.Neurol.Disord.Drug.Targets__Beta-caryophyllene, a CB2R selective agonist, protects against cognitive impairment caused by neuro-inflammation and not in dementia due to ageing induced by mitochondrial dysfunction
Kanuri_2021_HeartRhythm.Case.Rep_7_522Autoimmune dysautonomia secondary to chronic organophosphate exposure
Karami-Mohajeri_2021_J.Environ.Sci.Health.B__1Protective effect of Zataria multiflora Boiss. and its main compound, rosmarinic acid, against malathion induced oxidative stress and apoptosis in HepG2 cells
Karami_2021_Front.Aging.Neurosci_13_704583CSF and Plasma Cholinergic Markers in Patients With Cognitive Impairment
Karatas_2021_Fish.Physiol.Biochem__Effects of prolonged fasting on levels of metabolites, oxidative stress, immune-related gene expression, histopathology, and DNA damage in the liver and muscle tissues of rainbow trout (Oncorhynchus mykiss)
Karcz_2021_Int.J.Mol.Sci_22_Novel Coumarin-Thiadiazole Hybrids and Their Cu(II) and Zn(II) Complexes as Potential Antimicrobial Agents and Acetylcholinesterase Inhibitors
Kareem_2021_RSC.Adv_11_30781The recent development of donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's agents: highlights from 2010 to 2020
Karimi_2021_In.Silico.Pharmacol_9_13In vitro cholinesterase inhibitory action of Cannabis sativa L. Cannabaceae and in silico study of its selected phytocompounds
Karmakar_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109058Nonylphenol exposure in Labeo rohita (Ham.): Evaluation of behavioural response, histological, haematological and enzymatic alterations
Karottki_2021_Metab.Eng_66_114A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
Karunatillaka_2021_Proteins__Novel putative polyethylene terephthalate (PET) plastic degrading enzymes from the environmental metagenome
Kashi_2021_Food.Chem.X_12_100163Optimization of extraction conditions and determination of the Chlorpyrifos, Diazinon, and malathion residues in environment samples: Fruit (Apple, Orange, and Tomato)
Kashyap_2021_Enzyme.Microb.Technol_151_109922Disrupting putative N-glycosylation site N17 in lipase Lip11 of Yarrowia lipolytica yielded a catalytically efficient and thermostable variant accompanying conformational changes
Kassa_2021_Acta.Medica.(Hradec.Kralove)_64_145A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats
Kassa_2021_Neurotox.Res__Memantine and Its Combination with Acetylcholinesterase Inhibitors in Pharmacological Pretreatment of Soman Poisoning in Mice
Kato_2021_Intern.Med_60_1143Cholinesterase: Conflicting Aspects of Two Cardiovascular Diseases
Kato_2021_J.Biosci.Bioeng__Identification and characterization of an acetyl xylan esterase from Aspergillus oryzae
Kaur_2021_Bioorg.Chem_118_105479Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity
Kaur_2021_Enzyme.Microb.Technol_146_109760Protocol for in-vitro purification and refolding of hexachlorocyclohexane degrading enzyme haloalkane dehalogenase LinB from inclusion bodies
Kaur_2021_Phytother.Res__Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components
Kaur_2021_Toxicol.Res.(Camb)_10_40Neuroprotective effect of nerolidol in traumatic brain injury associated behavioural comorbidities in rats
Kausar_2021_RSC.Adv_12_154Design, synthesis, crystal structure, in vitro cytotoxicity evaluation, density functional theory calculations and docking studies of 2-(benzamido) benzohydrazide derivatives as potent AChE and BChE inhibitors
Kawabata_2021_J.Biosci.Bioeng__Asymmetric synthesis of intermediate for (1R,2S)-ethyl 1-amino-2-vinylcyclopropanecarboxylate by desymmetrization using engineered esterase from Bacillus subtilis
Kawai_2021_Angew.Chem.Int.Ed.Engl_60_10319Complete Biosynthetic Pathway of Alazopeptin, a Tripeptide Consisting of Two Molecules of 6-Diazo-5-oxo-l-norleucine and One Molecule of Alanine
Kawai_2021_Catalysts_11_206The Current State of Research on PET Hydrolyzing Enzymes Available for Biorecycling
Kawai_2021_ChemSusChem__Emerging Strategies in Polyethylene Terephthalate Hydrolase Research for Biorecycling
Kaygisiz_2021_Acta.Neuropsychiatr__1The effects of galangin in prepulse inhibition test and experimental schizophrenia models
Kazakova_2021_Int.J.Mol.Sci_22_Cytotoxic Potential of a-Azepano- and 3-Amino-3,4-SeCo-Triterpenoids
Ke_2021_Ecotoxicol.Environ.Saf_224_112666Heterologous expression and exploration of the enzymatic properties of the carbaryl hydrolase CarH from a newly isolated carbaryl-degrading strain
Keck_2021_Cell.Mol.Gastroenterol.Hepatol__Lack of mucosal cholinergic innervation is associated with increased risk of enterocolitis in Hirschsprung's disease
Keenan_2021_J.Lipid.Res_62_100016Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control
Keerthiraj_2021_Chem.Biodivers__Nematicidal and molecular docking investigation of essential oils from Pogostemon cablin ecotypes against Meloidogyne incognita
Kersten_2021_Curr.Opin.Lipidol__ANGPTL3 as therapeutic target
Kesavan_2021_Int.J.Mol.Sci_22_The Consequences of Soluble Epoxide Hydrolase Deletion on Tumorigenesis and Metastasis in a Mouse Model of Breast Cancer
Khadrawy_2021_Cardiovasc.Toxicol__The Effect of Curcumin Nanoparticles on Cisplatin-Induced Cardiotoxicity in Male Wistar Albino Rats
Khadrawy_2021_Eur.J.Pharmacol_908_174384Antidepressant effects of curcumin-coated iron oxide nanoparticles in a rat model of depression
Khadrawy_2021_Neurotoxicol_85_1Protective effect of nanocurcumin against neurotoxicity induced by doxorubicin in rat's brain
Khafaga_2021_Sci.Total.Environ_785_147384Boswellia serrata suppress fipronil-induced neuronal necrosis and neurobehavioral alterations via promoted inhibition of oxidative/inflammatory/apoptotic pathways
Khairy_2021_Environ.Sci.Process.Impacts__Sea urchin-like calcium borate microspheres and synergistic action with cholinesterase-inhibiting insecticides for ecofriendly Spodoptera littoralis control
Khalid_2021_Mar.Pollut.Bull_167_112295Are bio-based and biodegradable microplastics impacting for blue mussel (Mytilus edulis)?
Khamees_2021_Int.J.Clin.Pract__e14036No Impact of Soluble Epoxide Hydrolase rs4149243, rs2234914 and rs751142 Genetic Variants on the Development of Type II Diabetes and its Hypertensive Complication among Jordanian Patients
Khamphukdee_2021_Molecules_26_Antidementia Effects of Alternanthera philoxeroides in Ovariectomized Mice Supported by NMR-Based Metabolomic Analysis
Khan_2021_ACS.Infect.Dis_7_2876Total Synthesis of Tetrahydrolipstatin, Its Derivatives, and Evaluation of Their Ability to Potentiate Multiple Antibiotic Classes against Mycobacterium Species
Khan_2021_Exp.Appl.Acarol__Lethal and sublethal effects of emamectin benzoate on life-table and physiological parameters of citrus red mite, Panonychus citri
Khan_2021_Front.Pharmacol_12_678611Development of Synergy-Based Combination for Learning and Memory Using in vitro, in vivo and TLC-MS-Bioautographic Studies
Khanal_2021_Front.Pharmacol_12_785964Integration of System Biology Tools to Investigate Huperzine A as an Anti-Alzheimer Agent
Khandelwal_2021_Cell.Chem.Biol__Fatty acid chain length drives lysophosphatidylserine-dependent immunological outputs
Khaoula_2021_Mol.Biol.Rep_48_6999First characterization of congenital myasthenic syndrome type 5 in North Africa
Khetarpal_2021_PLoS.Genet_17_e1009802Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins
Kho_2021_Naunyn.Schmiedebergs.Arch.Pharmacol_394_559Donepezil induces ventricular arrhythmias by delayed repolarisation
Khobragade_2021_Biotechnol.Bioeng__Promoter Engineering-mediated Tuning of Esterase and Transaminase Expression for the Chemoenzymatic Synthesis of Sitagliptin Phosphate at the kilogram-scale
Khoma_2021_Ecotoxicol.Environ.Saf_208_111695Common and particular biochemical responses of Unio tumidus to herbicide, pharmaceuticals and their combined exposure with heating
Khoma_2021_Environ.Sci.Pollut.Res.Int__Environmental concentrations of Roundup in combination with chlorpromazine or heating causes biochemical disturbances in the bivalve mollusc Unio tumidus
Khuanjing_2021_Pharmacol.Res__105882Acetylcholinesterase inhibitor ameliorates doxorubicin-induced cardiotoxicity through reducing RIP1-mediated necroptosis
Khuanjing_2021_Transl.Res_230_82Donepezil attenuated cardiac ischemia/reperfusion injury through balancing mitochondrial dynamics, mitophagy, and autophagy
Khurana_2021_Neurotox.Res__Lacidipine Prevents Scopolamine-Induced Memory Impairment by Reducing Brain Oxido-nitrosative Stress in Mice
Khushboo_2021_Mini.Rev.Med.Chem__Biomedical Implications of Plant-Based Principles as Antidepressants: Prospects for Novel Drug Development
Kifle_2021_J.Environ.Public.Health_2021_6631721Drug Repurposing Approach, Potential Drugs, and Novel Drug Targets for COVID-19 Treatment
Kim_2021_Acta.Crystallogr.D.Struct.Biol_77_1451The structure of natively iodinated bovine thyroglobulin
Kim_2021_Angew.Chem.Int.Ed.Engl_60_19766Unprecedented Noncanonical Features of the Nonlinear Nonribosomal Peptide Synthetase Assembly Line for WS9326A Biosynthesis
Kim_2021_Antioxidants.(Basel)_10_Powdered Green Tea (Matcha) Attenuates the Cognitive Dysfunction via the Regulation of Systemic Inflammation in Chronic PM(2.5)-Exposed BALB/c Mice
Kim_2021_Antioxidants.(Basel)_11_Anti-Amnesic Effects of Epigallocatechin Gallate on Scopolamine-Induced Learning and Memory Dysfunction in Sprague-Dawley Rats
Kim_2021_Biomolecules_11_Nematicidal Activity of Benzyloxyalkanols against Pine Wood Nematode
Kim_2021_Cell.Death.Differ__Hevin-calcyon interaction promotes synaptic reorganization after brain injury
Kim_2021_ChemSusChem__Chemo-Biological Upcycling of Poly(ethylene terephthalate) to Multifunctional Coating Materials
Kim_2021_Environ.Toxicol.Pharmacol__103597Salinity-mediated changes in hematological parameters, stress, antioxidant responses, and acetylcholinesterase of juvenile olive flounders (Paralichthys olivaceus)
Kim_2021_Evid.Based.Complement.Alternat.Med_2021_8884243Standardized Extract (HemoHIM) Protects against Scopolamine-Induced Amnesia in a Murine Model
Kim_2021_Fish.Shellfish.Immunol__Effects on the survival rates, hematological parameters, and neurotransmitters in olive flounders, Paralichthys olivaceus, reared in bio-floc and seawater by Streptococcus iniae challenge
Kim_2021_Food.Sci.Biotechnol_30_287Neuroprotective effects of ethanolic extract from dry Rhodiola rosea L. rhizomes
Kim_2021_Int.J.Mol.Sci_22_Donepezil Regulates LPS and Abeta-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling
Kim_2021_J.Clin.Neurol_17_563Neostigmine for Treating Acute Colonic Pseudo-Obstruction in Neurocritically Ill Patients
Kim_2021_J.Enzyme.Inhib.Med.Chem_36_1049Inhibition of soluble epoxide hydrolase by phytochemical constituents of the root bark of Ulmus davidiana var. japonica
Kim_2021_J.Microbiol.Biotechnol_31_317Antioxidant and Antibacterial Activity of Caprylic Acid Vanillyl Ester Produced by Lipase-Mediated Transesterification
Kim_2021_Medicine.(Baltimore)_100_e24040Paradoxical pulmonary hemorrhage associated with hemocoagulase batroxobin in a patient with hemoptysis: A CARE-compliant case report
Kim_2021_Medicine.(Baltimore)_100_e26457Diagnostic yields and clinical features of ocular myasthenia gravis
Kim_2021_Molecules_26_Neuroprotective Effect and Antioxidant Potency of Fermented Cultured Wild Ginseng Root Extracts of Panax ginseng C.A. Meyer in Mice
Kim_2021_Pharmaceutics_13_In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics
Kim_2021_Plants.(Basel)_10_Simultaneous Quantification of Four Marker Compounds in Bauhinia coccinea Extract and Their Potential Inhibitory Effects on Alzheimer's Disease Biomarkers
Kim_2021_Prostate.Int_9_31Enhanced inhibition of tumor growth using TRAIL-overexpressing adipose-derived stem cells in combination with the chemotherapeutic agent CPT-11 in castration-resistant prostate cancer
Kim_2021_Yeungnam.Univ.J.Med_38_65Development of donepezil-induced hypokalemia following treatment of cognitive impairment
Kim_2021_iScience_24_102037Impaired formation of high-order gephyrin oligomers underlies gephyrin dysfunction-associated pathologies
Kinchen_2021_J.Proteome.Res__Long-Chain Acylcholines Link Butyrylcholinesterase to Regulation of Non-neuronal Cholinergic Signaling
Kirilovsky_2021_J.Toxicol.Environ.Health.A__1Effects of acute arsenic exposure in two different populations of Hyalella curvispina amphipods from North Patagonia Argentina
Kise_2021_Nature__Structural basis of gating modulation of Kv4 channel complexes
Kisova_2021_J.Biotechnol_335_55Removal of overpainting from an historical painting of the XVIII Century: A yeast enzymatic approach
Kitagawa_2021_J.Enzyme.Inhib.Med.Chem_36_1370Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators
Kitazawa_2021_Biol.Pharm.Bull_44_1717A Novel Function of Sphingosylphosphorylcholine on the Inhibitory Effects of Acetylcholinesterase Activity
Kiziltas_2021_Molecules_26_LC-HRMS Profiling and Antidiabetic, Anticholinergic, and Antioxidant Activities of Aerial Parts of Kinkor (Ferulago stellata)
Klatka_2021_Ann.Agric.Environ.Med_28_358Severe carbamates intoxication of 43-year-old farmer - case report
Klivinyi_2021_Br.J.Anaesth_126_700Perioperative use of physostigmine to reduce opioid consumption and peri-incisional hyperalgesia: a randomised controlled trial
Klussendorf_2021_Mol.Neurobiol__The Golgi-Associated PDZ Domain Protein Gopc/PIST Is Required for Synaptic Targeting of mGluR5
Kmezik_2021_J.Biol.Chem__100500A polysaccharide utilization locus from the gut bacterium Dysgonomonas mossii encodes functionally distinct carbohydrate esterases
Kmezik_2021_Sci.Rep_11_17662Characterization of a novel multidomain CE15-GH8 enzyme encoded by a polysaccharide utilization locus in the human gut bacterium Bacteroides eggerthii
Knobloch_2021_Chemosphere_262_128288Transformation of short-chain chlorinated paraffins by the bacterial haloalkane dehalogenase LinB - Formation of mono- and di-hydroxylated metabolites
Knobloch_2021_Chemosphere_283_131199Transformation of short-chain chlorinated paraffins and olefins with the bacterial dehalogenase LinB from Sphingobium Indicum - Kinetic models for the homologue-specific conversion of reactive and persistent material
Knoll-Gellida_2021_Toxicol.Sci__Hyperactivity and Seizure Induced by Tricresyl Phosphate Are Isomer-Specific and Not Linked to Phenyl Valerate-Neuropathy Target Esterase Activity Inhibition in Zebrafish
Knysh_2021_Bull.Environ.Contam.Toxicol__The Differential Effects of Salinity Level on Chlorpyrifos and Imidacloprid Toxicity to an Estuarine Amphipod
Ko_2021_Microb.Cell.Fact_20_232A novel protein fusion partner, carbohydrate-binding module family 66, to enhance heterologous protein expression in Escherichia coli
Kobenan_2021_Chem.Biodivers__Chemical composition and spectrum of insecticidal activity of the essential oils of Ocimumgratissimum L. and Cymbopogoncitratus Stapf on the main insects of the cotton entomofauna in Cte d'Ivoire
Kobzev_2021_Mol.Divers__Synthesis of 8-phenyl substituted 3-benzazecines with allene moiety, their thermal rearrangement and evaluation as acetylcholinesterase inhibitors
Koca_2021_Mol.Divers__New benzamide derivatives and their nicotinamide/cinnamamide analogs as cholinesterase inhibitors
Koczyk_2021_J.Fungi.(Basel)_7_285Terpenoid Biosynthesis Dominates among Secondary Metabolite Clusters in Mucoromycotina Genomes
Koganezawa_2021_Biochem.Biophys.Res.Commun_582_144Super-resolved 3D-STED microscopy identifies a layer-specific increase in excitatory synapses in the hippocampal CA1 region of Neuroligin-3 KO mice
Koike_2021_Cell.Tissue.Res__Distribution, fine structure, and three-dimensional innervation of lamellar corpuscles in rat plantar skin
Koike_2021_Free.Radic.Biol.Med__Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic beta-cell dysfunction and loss
Kokkonen_2021_RSC.Chem.Biol_2_645Substrate inhibition by the blockage of product release and its control by tunnel engineering
Kokona_2021_Neuropharmacol_185_108450The endocannabinoid 2-arachidonoylglycerol and dual ABHD6/MAGL enzyme inhibitors display neuroprotective and anti-inflammatory actions in the in vivo retinal model of AMPA excitotoxicity
Kolaczkowski_2021_Glycobiology__Analysis of fungal high mannose structures using CAZymes
Koller_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122693Release of protein-bound nerve agents by excess fluoride from whole blood: GC-MS/MS method development, validation, and application to a real-life denatured blood sample
Koloski_2021_Ticks.Tick.Borne.Dis_13_101827Transcriptional profiling of Dermacentor variabilis (Acari: Ixodidae) provides insights into the role of the Haller's organ in spatial DEET recognition
Komagata_2021_Insect.Biochem.Mol.Biol__103637Common substitution mutation F348Y of acetylcholinesterase gene contributes to organophosphate and carbamate resistance in Cimex lectularius and C. hemipterus
Komali_2021_J.Tradit.Complement.Med_11_137Antiepileptic potential of Bacopa monnieri in the rat brain during PTZ-induced epilepsy with reference to cholinergic system and ATPases
Komorizono_2021_Diabetes.Obes.Metab_23_832Metformin dose increase versus added linagliptin in non-alcoholic fatty liver disease and type 2 diabetes: An analysis of the J-LINK study
Kondak_2021_J.Neurochem__Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine
Kong_2021_Ecotoxicol.Environ.Saf_225_112710Old pesticide, new use: Smart and safe enantiomer of isocarbophos in locust control
Kong_2021_Mol.Psychiatry__Reducing alcohol and/or cocaine-induced reward and toxicity via an epidermal stem cell-based gene delivery platform
Kong_2021_Molecules_26_Potential of Naturally Derived Alkaloids as Multi-Targeted Therapeutic Agents for Neurodegenerative Diseases
Koodalingam_2021_Pestic.Biochem.Physiol_176_104882Studies on biochemical and synergistic effects of immunosuppressive concentration of imidacloprid with Beauveria bassiana and Metarhizium anisopliae for enhancement of virulence against vector mosquito Culex quinquefasciatus
Korabecny_2021_Biomolecules_11_Cholinesterase Research
Kos_2021_Int.J.Mol.Sci_22_Synthesis and Hybrid SAR Property Modeling of Novel Cholinesterase Inhibitors
Kotake_2021_Intern.Med__Cholinergic Crisis Owing to Distigmine Bromide Complicated by Hyperosmolar Hyperglycemic State
Kotnala_2021_Clin.Sci.(Lond)_135_2067Contribution of dipeptidyl peptidase 4 to non-typeable Haemophilus influenzae-induced lung inflammation in COPD
Kovari_2021_J.Neuroendocrinol__e13079Tanycyte specific ablation of diacylglycerol lipase alpha stimulates the hypothalamic-pituitary-thyroid axis by decreasing the endocannabinoid mediated inhibition of TRH release
Kovrov_2021_J.Lipid.Res__100144Lipoprotein size is a main determinant for the rate of hydrolysis by exogenous lipoprotein lipase in human plasma
Kowalczyk_2021_Biomacromolecules__Dual Effect of Prussian Blue Nanoparticles on Abeta40 Aggregation: beta-Sheet Fibril Reduction and Copper Dyshomeostasis Regulation
Krams_2021_Int.J.Environ.Res.Public.Health_18_The Obesity Paradox Predicts the Second Wave of COVID-19 to Be Severe in Western Countries
Kratasyuk_2021_Sensors.(Basel)_21_Software for Matching Standard Activity Enzyme Biosensors for Soil Pollution Analysis
Kratky_2021_Bioorg.Chem_116_105301Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study
Kratky_2021_Molecules_26_Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase
Kratky_2021_Pharmaceuticals.(Basel)_14_Novel Aminoguanidine Hydrazone Analogues: From Potential Antimicrobial Agents to Potent Cholinesterase Inhibitors
Kratz_2021_J.Mass.Spectrom.Adv.Clin.Lab_22_56Endocannabinoids as potential biomarkers: It's all about pre-analytics
Krejner-Bienias_2021_Arch.Immunol.Ther.Exp.(Warsz)_69_1DPP4 Inhibitors and COVID-19-Holy Grail or Another Dead End?
Krishnendu_2021_Curr.Top.Med.Chem__Formulating The Structural Aspects Of Various Benzimidazole Cognates
Kristensen_2021_Front.Cell.Dev.Biol_9_702508GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity
Krokidis_2021_Adv.Exp.Med.Biol_1338_193Bioinformatics Approaches for Parkinson's Disease in Clinical Practice: Data-Driven Biomarkers and Pharmacological Treatment
Krska_2021_Biochemistry__Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii
Krzyzowski_2021_Molecules_26_Intergenerational Transmission of Resistance of Callosobruchus maculatus to Essential Oil Treatment
Kshirsagar_2021_Neurotox.Res__Hydrogen Sulfide Ameliorates Lipopolysaccharide-Induced Memory Impairment in Mice by Reducing Apoptosis, Oxidative, and Inflammatory Effects
Kublicki_2021_Crit.Rev.Biotechnol__1Wheat germ lipase: isolation, purification and applications
Kuentzel_2021_Int.J.Mol.Sci_22_Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth
Kulakova_2021_Biomed.Khim_67_300[Molecular mechanism of chromogenic substrate hydrolysis in the active site of human carboxylesterase-1]
Kulkarni_2021_Eur.J.Pharm.Biopharm__Design, development and in-vitro/in-vivo evaluation of intranasally delivered Rivastigmine and N-Acetyl Cysteine loaded bifunctional niosomes for applications in combinative treatment of Alzheimer's disease
Kulminskaya_2021_J.Biol.Chem__101206Optimized expression and purification of adipose triglyceride lipase improved hydrolysis and transacylation catalytic activities in vitro
Kumar_2021_Anal.Biochem_633_114402Fluorimetric method for specific detection of human serum albumin in urine using its pseudoesterase property
Kumar_2021_Biochem.Biophys.Res.Commun_577_52Arbutin protects brain against middle cerebral artery occlusion-reperfusion (MCAo/R) injury
Kumar_2021_Biochemistry__A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster
Kumar_2021_Curr.Drug.Targets__A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer's Disease
Kumar_2021_Curr.Med.Chem__Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer's Disease
Kumar_2021_Eur.J.Pharmacol_911_174529Ameliorative effect of myrcene in mouse model of Alzheimer's disease
Kumar_2021_Food.Chem_361_130031Lipase - The fascinating dynamics of enzyme in seed storage and germination - A real challenge to pearl millet
Kumar_2021_Front.Pharmacol_12_737137Five-Decade Update on Chemopreventive and Other Pharmacological Potential of Kurarinone: a Natural Flavanone
Kumar_2021_Life.Sci__119115Pancreatic lipase inhibitors: The road voyaged and successes
Kumar_2021_Mar.Pollut.Bull_170_112682Metal determination and biochemical status of marine fishes facilitate the biomonitoring of marine pollution
Kumar_2021_Neurochem.Int_151_105217Arbutin attenuates monosodium L-glutamate induced neurotoxicity and cognitive dysfunction in rats
Kumar_2021_PLoS.One_16_e0258106Staphylococcus aureus Lipase 3 (SAL3) is a surface-associated lipase that hydrolyzes short chain fatty acids
Kumar_2021_Saudi.J.Biol.Sci_28_754Cholinesterase inhibitory activity of highly functionalized fluorinated spiropyrrolidine heterocyclic hybrids
Kumar_2021_Talanta_224_121906Pseudosterase activity-based specific detection of human serum albumin on gel
Kumar_2021_Ticks.Tick.Borne.Dis_12_101818Characterization of deltamethrin, cypermethrin, coumaphos and ivermectin resistance in populations of Rhipicephalus microplus in India and efficacy of an antitick natural formulation prepared from Ageratum conyzoides
Kumari_2021_Biomedicines_9_The Importance of Lipoprotein Lipase Regulation in Atherosclerosis
Kumari_2021_Future.Microbiol__The lipolytic activity of LipJ, a stress-induced enzyme, is regulated by its C-terminal adenylate cyclase domain
Kumawat_2021_J.Phys.Chem.B__Organoselenium Compounds as Acetylcholinesterase Inhibitors: Evidence and Mechanism of Mixed Inhibition
Kundo_2021_Biomed.Res.Int_2021_9154406Identification of Polyphenolics from Loranthus globosus as Potential Inhibitors of Cholinesterase and Oxidative Stress for Alzheimer's Disease Treatment
Kundrick_2021_Neurotoxicol_82_130Cannabidiol reduces soman-induced lethality and seizure severity in female plasma carboxylesterase knockout mice treated with midazolam
Kundu_2021_Drug.Dev.Ind.Pharm__1Potential alternatives to current cholinesterase inhibitors: An in silico drug repurposing approach
Kunkeaw_2021_Sci.Rep_11_23796Diplazium esculentum (Retz.) Sw. reduces BACE-1 activities and amyloid peptides accumulation in Drosophila models of Alzheimer's disease
Kunnaja_2021_Molecules_26_In Vitro Antioxidant Activity of Litsea martabanica Root Extract and Its Hepatoprotective Effect on Chlorpyrifos-Induced Toxicity in Rats
Kurach_2021_Int.J.Mol.Sci_22_Mechanisms of the Procognitive Effects of Xanthotoxin and Umbelliferone on LPS-Induced Amnesia in Mice
Kurt-Celep_2021_Food.Chem.Toxicol__112330Comprehensive evaluation of two Astragalus species (A. campylosema and A. hirsutus) based on biological, toxicological properties and chemical profiling
Kuschpel_2021_Neurology_97_964Reader Response: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Kuvelkar_2021_Indian.J.Pathol.Microbiol_64_266Estimation of plasma and RBC acetylcholinesterase in children: An evaluation tool for Hirschsprung's disease?
Kuwahata_2021_Circ.Rep_3_115Effect of QT Prolongation in Patients Taking Cholinesterase Inhibitors (Donepezil) for Alzheimer's Disease
Kwon_2021_Acute.Crit.Care__Continuous renal replacement therapy increased plasma cholinesterase activity in a case of acute organophosphate poisoning
Labar_2021_Biomolecules_11_533Structure and Dynamics of an Archeal Monoglyceride Lipase from Palaeococcus ferrophilus as Revealed by Crystallography and In Silico Analysis
Labban_2021_Behav.Brain.Res__113100Effects of Melatonin and Resveratrol on Recognition Memory and Passive Avoidance Performance in a Mouse Model of Alzheimer's Disease
Lage-Vickers_2021_Commun.Biol_4_103The expression of YWHAZ and NDRG1 predicts aggressive outcome in human prostate cancer
Lagrutta_2021_Heliyon_7_e06539Nuclear-lipid-droplet proteome: carboxylesterase as a nuclear lipase involved in lipid-droplet homeostasis
Lai_2021_Front.Neural.Circuits_15_676891An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum
Lajmanovich_2021_Sci.Total.Environ_804_150177Glyphosate and glufosinate ammonium, herbicides commonly used on genetically modified crops, and their interaction with microplastics: Ecotoxicity in anuran tadpoles
Lamb_2021_Environ.Sci.Process.Impacts__Towards a comprehensive understanding of malathion degradation: theoretical investigation of degradation pathways and related kinetics under alkaline conditions
Lambre_2021_EFSA.J_19_e06561Safety evaluation of the food enzyme triacylglycerol lipase from the genetically modified Aspergillus luchuensis strain FL100SC
Lambre_2021_EFSA.J_19_e07006Safety evaluation of the food enzyme rennet paste from the abomasum of suckling goats, lambs and calves
Lan_2021_J.Agric.Food.Chem__Structure-Guided Rational Design of a Mono- and Diacylglycerol Lipase from Aspergillus oryzae: A Single Residue Mutant Increases the Hydrolysis Ability
Lan_2021_J.Chem.Inf.Model__Glycerol is Released from a New Path in MGL Lipase Catalytic Process
Landete_2021_Int.J.Food.Sci.Nutr__1The use of Lactobacillus plantarum esterase genes: a biotechnological strategy to increase the bioavailability of dietary phenolic compounds in lactic acid bacteria
Lane_2021_BMC.Fam.Pract_22_51Primary care physician volume and quality of care for older adults with dementia: a retrospective cohort study
Lanzarin_2021_Biomedicines_9_Inflammatory, Oxidative Stress, and Apoptosis Effects in Zebrafish Larvae after Rapid Exposure to a Commercial Glyphosate Formulation
Latif_2021_Drug.Dev.Res_82_207New multitarget directed benzimidazole-2-thiol-based heterocycles as prospective anti-radical and anti-Alzheimer's agents
Lauwers_2021_Osteoarthritis.Cartilage__The cholinergic system in joint health and osteoarthritis: a narrative-review
Lazarova_2021_J.Alzheimers.Dis__Effects of New Galantamine Derivatives in a Scopolamine Model of Dementia in Mice
Lazarova_2021_J.Alzheimers.Dis__2New Galantamine Derivatives with Inhibitory Effect on Acetylcholinesterase Activity
Lazewska_2021_Molecules_26_Biphenylalkoxyamine Derivatives-Histamine H(3) Receptor Ligands with Butyrylcholinesterase Inhibitory Activity
Le Douce_2021_Front.Neurosci_15_651094Subcommissural Organ-Spondin-Derived Peptide Restores Memory in a Mouse Model of Alzheimer's Disease
Le Du-Carree_2021_Sci.Total.Environ_784_147162Immunological and metabolic effects of acute sublethal exposure to glyphosate or glyphosate-based herbicides on juvenile rainbow trout, Oncorhynchus mykiss
Le_2021_Evid.Based.Complement.Alternat.Med_2021_6627648Ocimum sanctum Linn. Extract Improves Cognitive Deficits in Olfactory Bulbectomized Mice via the Enhancement of Central Cholinergic Systems and VEGF Expression
Le_2021_FASEB.J_35_e21961Differential expression and hypoxia-mediated regulation of the N-myc downstream regulated gene family
League_2021_Front.Neurol_12_651272Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat
Lecoutey_2021_Molecules_26_Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer's Disease Treatment through Rigidification Strategy
Lee_2021_ACS.Nano__Imaging Strategy that Achieves Ultrahigh Contrast by Utilizing Differential Esterase Activity in Organs: Application in Early Detection of Pancreatic Cancer
Lee_2021_Adv.Exp.Med.Biol_1187_23Phospholipase Signaling in Breast Cancer
Lee_2021_Anim.Biosci_34_1029Application of lactic acid bacteria producing antifungal substance and carboxylesterase on whole crop rice silage with different dry matter
Lee_2021_Br.J.Pharmacol__Alternative Pain Management via Endocannabinoids in the Time of the Opioid Epidemic: Peripheral Neuromodulation and Pharmacological Interventions
Lee_2021_Cell.Rep.Phys.Sci_2_A self-degradable hydrogel sensor for a nerve agent tabun surrogate through a self-propagating cascade
Lee_2021_Eur.J.Clin.Pharmacol__Post-market utilization patterns of Alzheimer's disease treatments in South Korea: comparison with countries with universal health coverage
Lee_2021_Front.Physiol_12_643389Interactive Gene Expression Between Metarhizium anisopliae JEF-290 and Longhorned Tick Haemaphysalis longicornis at Early Stage of Infection
Lee_2021_Int.J.Biol.Macromol_190_441Mining of a novel esterase (est3S) gene from a cow rumen metagenomic library with organosphosphorus insecticides degrading capability: Catalytic insights by site directed mutations, docking, and molecular dynamic simulations
Lee_2021_J.Enzyme.Inhib.Med.Chem_36_437Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates
Lee_2021_Molecules_26_Characterization and Study on Fragmentation Pathways of a Novel Nerve Agent, 'Novichok (A234)', in Aqueous Solution by Liquid Chromatography-Tandem Mass Spectrometry
Lee_2021_Nutrients_13_DW2009 Elevates the Efficacy of Donepezil against Cognitive Impairment in Mice
Lee_2021_Pharmaceutics_13_Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay
Lei_2021_Microb.Cell.Fact_20_197Degradation of epigallocatechin and epicatechin gallates by a novel tannase Tan(Hcw) from Herbaspirillum camelliae
Leineweber_2021_J.Zoo.Wildl.Med_51_948Clinical chemistry, vitamin, electrophoresis, and hematologic analytes of black-headed ibis (Threskiornis melanocephalus)
Leitao_2021_Int.J.Mol.Sci_22_Structural Insights into Carboxylic Polyester-Degrading Enzymes and Their Functional Depolymerizing Neighbors
Leite_2021_Foods_10_Chemical Profile and Evaluation of the Antioxidant and Anti-Acetylcholinesterase Activities of Annona squamosa L. (Annonaceae) Extracts
Lemire_2021_Am.J.Hum.Genet__ABHD16A deficiency causes a complicated form of hereditary spastic paraplegia associated with intellectual disability and cerebral anomalies
Lemus_2021_J.Pain.Symptom.Manage__Sugammadex to reverse neuromuscular blockade prior to withdrawal of life support
Leng_2021_Nat.Rev.Neurol_17_157Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Leon_2021_S.Afr.J.Bot_136_91Alkaloids of Phaedranassa dubia (Kunth) J.F. Macbr. and Phaedranassa brevifolia Meerow (Amaryllidaceae) from Ecuador and its cholinesterase-inhibitory activity
Leonard_2021_J.Food.Sci__Effect of extrusion technology on hempseed (Cannabis sativa L.) oil cake: Polyphenol profile and biological activities
Les_2021_Biology.(Basel)_10_Jasonia glutinosa (L.) DC., a Traditional Herbal Tea, Exerts Antioxidant and Neuroprotective Properties in Different In Vitro and In Vivo Systems
Leth-Espensen_2021_Proc.Natl.Acad.Sci.U.S.A_118_e2026650118The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding
Leung_2021_J.Neurochem_158_1236Cryo-electron microscopy of cholinesterases, present and future
Levano_2021_Mol.Genet.Genomic.Med_9_e1764Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients
Levernier_2021_Chemistry_27_8782Phenyl Silicates with Substituted Catecholate Ligands: Synthesis, Structural Studies and Reactivity
Li-Beisson_2021_New.Phytol__The disassembly of lipid droplets in Chlamydomonas
Li_2021_Acta.Pharmacol.Sin__1Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
Li_2021_Adv.Synth.Catal_362_4699Reprogramming Epoxide Hydrolase to Improve Enantioconvergence in Hydrolysis of Styrene Oxide Scaffolds
Li_2021_Anal.Chem_93_7362pH and Redox Dual-Response Disulfide Bond-Functionalized Red-Emitting Gold Nanoclusters for Monitoring the Contamination of Organophosphorus Pesticides in Foods
Li_2021_Anal.Chem_93_8161Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling
Li_2021_Anim.Biosci__mTOR and ERK1/2 signaling participate in the process of acetate regulating lipid metabolism and HSL expression
Li_2021_Ann.Thorac.Surg__Outcomes of juvenile myasthenia gravis: a comparison of robotic thymectomy with medication treatment
Li_2021_Antimicrob.Agents.Chemother__AAC0060221Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells
Li_2021_Appl.Biochem.Biotechnol__Enhanced Secretory Expression and Surface Display Level of Bombyx mori Acetylcholinesterase 2 by Pichia pastoris Based on Codon Optimization Strategy for Pesticides Setection
Li_2021_Biomacromolecules_22_2256Synthesis, Enzymatic Degradation, and Polymer-Miscibility Evaluation of Nonionic Antimicrobial Hyperbranched Polyesters with Indole or Isatin Functionalities
Li_2021_Bioorg.Chem_110_104826Inducing new bioactive metabolites production from coculture of Pestalotiopsis sp. and Penicillium bialowiezense
Li_2021_Cardiovasc.Drugs.Ther_35_877Impact of Peripheral alpha7-Nicotinic Acetylcholine Receptors on Cardioprotective Effects of Donepezil in Chronic Heart Failure Rats
Li_2021_Chem.Biol.Interact__109392Neuroprotective effects of protocatechuic acid on sodium arsenate induced toxicity in mice: Role of oxidative stress, inflammation, and apoptosis
Li_2021_Chem.Commun.(Camb)_57_8909A pendant droplet-based sensor for the detection of acetylcholinesterase and its inhibitors
Li_2021_Chemosphere_263_128238The association between toxic pesticide environmental exposure and Alzheimer's disease: A scientometric and visualization analysis
Li_2021_Chirality_33_62A novel lipase from Aspergillus oryzae WZ007 catalyzed synthesis of brivaracetam intermediate and its enzymatic characterization
Li_2021_Comb.Chem.High.Throughput.Screen_24_986Prognostic Significance of Hematopoietic-cell Serglycin for the Survival of Hepatocellular Carcinoma: A Single-center Retrospective Study
Li_2021_Commun.Biol_4_144Dipeptidyl peptidase 4 promotes peritoneal fibrosis and its inhibitions prevent failure of peritoneal dialysis
Li_2021_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110630Identification, characterization and mRNA transcript abundance profiles of the carboxylesterase (CXE5) gene in Eriocheir sinensis suggest that it may play a role in methyl farnesoate degradation
Li_2021_Data.Brief_36_107045Data for the lipase catalyzed synthesis of cyano-containing multi-substituted indoles
Li_2021_Drug.Des.Devel.Ther_15_1883Study on Hepatotoxicity of Rhubarb Based on Metabolomics and Network Pharmacology
Li_2021_Drug.Metab.Dispos__Contributions of Cathepsin A and Carboxylesterase 1 to the hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis
Li_2021_Environ.Health.Perspect_129_47008Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition
Li_2021_Enzyme.Microb.Technol_144_109741Preparation of a Bombyx mori acetylcholinesterase enzyme reagent through chaperone protein disulfide isomerase co-expression strategy in Pichia pastoris for detection of pesticides
Li_2021_Eur.J.Med.Chem_225_113765Identification and structure-activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus
Li_2021_Eur.J.Med.Chem_229_114045The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression
Li_2021_Evid.Based.Complement.Alternat.Med_2021_7357521Enteral Nutrition Combined with Improved-Sijunzi Decoction Shows Positive Effect in Precachexia Cancer Patients: A Retrospective Analysis
Li_2021_Exp.Appl.Acarol__Acetylcholinesterase target sites for developing environmentally friendly insecticides against Tetranychus urticae (Acari: Tetranychidae)
Li_2021_Food.Chem_373_131285Molecular dynamics revealed the effect of epoxy group on triglyceride digestion
Li_2021_Food.Sci.Nutr_9_2349Extraction and purification of total flavonoids from Eupatorium lindleyanum DC. and evaluation of their antioxidant and enzyme inhibitory activities
Li_2021_Front.Aging.Neurosci_13_770948Electro-Acupuncture Improve the Early Pattern Separation in Alzheimer's Disease Mice via Basal Forebrain-Hippocampus Cholinergic Neural Circuit
Li_2021_Front.Cell.Dev.Biol_9_640667Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes
Li_2021_Front.Chem_9_713104A Multi-Catalytic Sensing for Hydrogen Peroxide, Glucose, and Organophosphorus Pesticides Based on Carbon Dots
Li_2021_Front.Oncol_11_679816Antidiabetic Agent DPP-4i Facilitates Murine Breast Cancer Metastasis by Oncogenic ROS-NRF2-HO-1 Axis via a Positive NRF2-HO-1 Feedback Loop
Li_2021_Int.Immunopharmacol_99_107920IL-6 downregulates hepatic carboxylesterases via NF-kappaB activation in dextran sulfate sodium-induced colitis
Li_2021_Int.J.Biol.Macromol_169_18Biological detoxification of fumonisin by a novel carboxylesterase from Sphingomonadales bacterium and its biochemical characterization
Li_2021_J.Agric.Food.Chem_69_5481A Highly Efficient Three-Liquid-Phase-Based Enzymatic One-Pot Multistep Reaction System with Recoverable Enzymes for the Synthesis of Biodiesel
Li_2021_J.Agric.Food.Chem_69_6087Inorganic Recognizer-Assisted Homogeneous Electrochemiluminescence Determination of Organophosphorus Pesticides via Target-Controlled Emitter Release
Li_2021_J.Asian.Nat.Prod.Res_24_88Bisabolanoic acid A, a new polychiral sesquiterpene with AChE inhibitory activity from a mangrove-derived fungus Colletotrichum sp
Li_2021_J.Asian.Nat.Prod.Res__1New 2-(2-Phenylethyl)chromone derivatives from agarwood originating from Aquilaria sinensis
Li_2021_J.Cancer.Res.Ther_17_644BCL6B hypermethylation predicts metastasis and poor prognosis in early-stage hepatocellular carcinoma after thermal ablation
Li_2021_J.Cell.Physiol_236_4435Reduced neuropathy target esterase in pre-eclampsia suppresses tube formation of HUVECs via dysregulation of phospholipid metabolism
Li_2021_J.Chromatogr.A_1663_462784Screening and identification of acetylcholinesterase inhibitors from Terminalia chebula fruits by immobilized enzyme on cellulose filter paper coupled with ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry and molecular docking
Li_2021_J.Clin.Invest__sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae
Li_2021_J.Food.Sci__Enzymatic acylation of rutin with benzoic acid ester and lipophilic, antiradical, and antiproliferative properties of the acylated derivatives
Li_2021_J.Med.Chem__Highly Potent and Selective Butyrylcholinesterase Inhibitors for Cognitive Improvement and Neuroprotection
Li_2021_J.Mol.Histol__Prednisolone induces osteocytes apoptosis by promoting Notum expression and inhibiting PI3K/AKT/GSK3beta/beta-catenin pathway
Li_2021_J.Pharm.Anal_11_183A dual-signal sensor for the analysis of parathion-methyl using silver nanoparticles modified with graphitic carbon nitride
Li_2021_Life.Sci_283_119866Morphine increases myocardial triacylglycerol through regulating adipose triglyceride lipase S406 phosphorylation
Li_2021_Medicine.(Baltimore)_100_e26662Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials
Li_2021_Mikrochim.Acta_188_385A ratiometric fluorescence strategy based on inner filter effect for Cu(2+)-mediated detection of acetylcholinesterase
Li_2021_Molecules_26_Phytochemical Composition, Antioxidant Activity, and Enzyme Inhibitory Activities (alpha-Glucosidase, Xanthine Oxidase, and Acetylcholinesterase) of Musella lasiocarpa
Li_2021_Nat.Prod.Res_35_763(-)-Grandiflorimine, a new dibenzopyrrocoline alkaloid with cholinesterase inhibitory activity from Illigera grandiflora
Li_2021_Nat.Prod.Res__1A new diterpenoid alkaloid from Delphinium gyalanum C. Marquand & Airy Shaw
Li_2021_PLoS.One_16_e0247236Molecular dynamics investigation of the interaction between Colletotrichum capsici cutinase and berberine suggested a mechanism for reduced enzyme activity
Li_2021_Pestic.Biochem.Physiol_172_104769Biogenetic cantharidin is a promising leading compound to manage insecticide resistance of Mythimna separata (Lepidoptera: Noctuidae)
Li_2021_Pharmaceutics_13_Activation of Tenofovir Alafenamide and Sofosbuvir in the Human Lung and Its Implications in the Development of Nucleoside/Nucleotide Prodrugs for Treating SARS-CoV-2 Pulmonary Infection
Li_2021_Phytochem.Anal_32_640On-line coupling pressurised liquid extraction with two-dimensional counter current chromatography for isolation of natural acetylcholinesterase inhibitors from Astragalus membranaceus
Li_2021_Plant.J__Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development
Li_2021_SLAS.Discov__24725552211030897Identification of Compounds for Butyrylcholinesterase Inhibition
Li_2021_Sci.Rep_11_6913Characterization of a novel sn1,3 lipase from Ricinus communis L. suitable for production of oleic acid-palmitic acid-glycerol oleate
Li_2021_Stem.Cell.Res_53_102313A non-integrated iPSC line (SDQLCHi042-A) from a boy suffering from familial combined hyperlipidemia with compound heterozygous mutations of lipoprotein lipase gene
Li_2021_Zhen.Ci.Yan.Jiu_46_851[Acupuncture improves cognitive function of vascular dementia rats by regulating PI3K/Akt/mTOR pathway]
Liakath-Ali_2021_Front.Mol.Neurosci_14_659681The Perils of Navigating Activity-Dependent Alternative Splicing of Neurexins
Lian_2021_J.Lipid.Res__100093Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver
Liang_2021_Biosens.Bioelectron_193_113553A novel biosensor based on multienzyme microcapsules constructed from covalent-organic framework
Liang_2021_J.Environ.Sci.Health.B__1Insecticidal and acetylcholine esterase inhibition activity of Rhododendron thymifolium essential oil and its main constituent against two stored product insects
Liao_2021_Genes.(Basel)_12_Functional Haplotype of LIPC Induces Triglyceride-Mediated Suppression of HDL-C Levels According to Genome-Wide Association Studies
Ligaj_2021_Talanta_223_121749Electrochemical screening of genoprotective and antioxidative effectiveness of Origanum vulgare L. and its functionality in the prevention of neurodegenerative disorders
Lillich_2021_J.Med.Chem_64_17259Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor gamma Agonists/Soluble Epoxide Hydrolase Inhibitors
Lim_2021_Int.J.Biol.Macromol_186_414Identification of regions affecting enzyme activity, substrate binding, dimer stabilization and polyhydroxyalkanoate (PHA) granule morphology in the PHA synthase of Aquitalea sp. USM4
Lim_2021_J.Inflamm.Res_14_6833Polymorphism rs10105606 of LPL as a Novel Risk Factor for Microalbuminuria
Lima_2021_Int.J.Biol.Macromol_167_1361Anti-acetylcholinesterase and toxicity against Artemia salina of chitosan microparticles loaded with essential oils of Cymbopogon flexuosus, Pelargonium x ssp and Copaifera officinalis
Lima_2021_J.Biomol.Struct.Dyn__1Diterpene Sonderianin isolated from Croton blanchetianus exhibits acetylcholinesterase inhibitory action and anxiolytic effect in adult zebrafish (Danio rerio) by 5-HT system
Limonta_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109037Effects of microplastics on head kidney gene expression and enzymatic biomarkers in adult zebrafish
Lin_2021_ACS.Chem.Neurosci__Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22
Lin_2021_Exp.Ther.Med_21_548Curcumin relieves mice gastric emptying dysfunction induced by L-arginine and atropine through interstitial cells of Cajal
Lin_2021_Front.Pharmacol_12_754554Antioxidant Effects of Sophora davidi (Franch.) Skeels on d-Galactose-Induced Aging Model in Mice via Activating the SIRT1/p53 Pathway
Linari_2021_J.Vet.Diagn.Invest__10406387211021345Evaluation of 1,2-O-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin) ester (DGGR) and 1,2-diglyceride lipase assays in dogs with naturally occurring hypercortisolism
Lindgren_2021_J.Alzheimers.Dis__Differences in Dementia Care Between Swedish-Born and Foreign-Born from Countries with Different Country Level Socioeconomic Position: A Nationwide Register-Based Study
Liou_2021_Antioxidants.(Basel)_10_Oxidative Stress Biomarkers and Mitochondrial DNA Copy Number Associated with APOE4 Allele and Cholinesterase Inhibitor Therapy in Patients with Alzheimer's Disease
Lirio_2021_Dalton.Trans_50_1866Fast multipoint immobilization of lipase through chiral L-proline on a MOF as a chiral bioreactor
Lisboa_2021_Ecotoxicol.Environ.Saf_214_112049Ecotoxicological responses of Eisenia andrei exposed in field-contaminated soils by sanitary sewage
Liu_2021_Anal.Chim.Acta_1184_339026A BCNO QDs-MnO(2) nanosheets based fluorescence off-on-off and colorimetric sensor with smartphone detector for the detection of organophosphorus pesticides
Liu_2021_Analyst_145_7849Cu(2+)-Regulated reversible coordination interaction of GQD@Tb/GMP ICP nanoparticles: towards directly monitoring cerebrospinal acetylcholinesterase as a biomarker for cholinic brain dysfunction
Liu_2021_Aquat.Toxicol_242_106039Chlorogenic acid alleviates thioacetamide-induced toxicity and promotes liver development in zebrafish (Danio rerio) through the Wnt signaling pathway
Liu_2021_Arch.Insect.Biochem.Physiol__e21859Decreased carboxylesterase expression associated with increased susceptibility to insecticide in Mythimna separata
Liu_2021_Asian.J.Androl_23_109Clinical significance of EPHX2 deregulation in prostate cancer
Liu_2021_Biology.(Basel)_10_Enhancement of Fear Extinction Memory and Resistance to Age-Related Cognitive Decline in Butyrylcholinesterase Knockout Mice and (R)-Bambuterol Treated Mice
Liu_2021_Biomolecules_11_1552Identification and Biochemical Characterization of a Novel Hormone-Sensitive Lipase Family Esterase Est19 from the Antarctic Bacterium Pseudomonas sp. E2-15
Liu_2021_Bioresour.Technol_332_124967Directed evolution of feruloyl esterase from Lactobacillus acidophilus and its application for ferulic acid production
Liu_2021_Biosens.Bioelectron_199_113906Portable electrochemical biosensor based on laser-induced graphene and MnO(2) switch-bridged DNA signal amplification for sensitive detection of pesticide
Liu_2021_Biotechnol.Adv_48_107730Biodegradation and up-cycling of polyurethanes: Progress, challenges, and prospects
Liu_2021_Cancer.Chemother.Pharmacol__Carboxylesterase 1 polymorphisms are associated with clinical outcomes in gastroenteric cancer patients treated with capecitabine
Liu_2021_Catal.Sci.Technol__Reshaping the active pocket of esterase Est816 for resolution of economically important racemates
Liu_2021_Chem.Res.Toxicol__LC-MS/MS Analysis of the Formation and Loss of DNA Adducts in Rats Exposed to Vinyl Acetate Monomer through Inhalation
Liu_2021_Chemosphere_288_132492Reproductive stimulation and energy allocation variation of BDE-47 and its derivatives on Daphnia magna
Liu_2021_Enzyme.Microb.Technol_148_109818Synthesis of lipophilic arbutin ester by enzymatic transesterification in high pressure carbon dioxide
Liu_2021_Eur.J.Med.Chem_227_113973Design, synthesis, and biological evaluation of novel (4-(1,2,4-oxadiazol-5-yl)phenyl)-2-aminoacetamide derivatives as multifunctional agents for the treatment of Alzheimer's disease
Liu_2021_Eur.J.Med.Chem_229_114044Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease
Liu_2021_Eur.J.Med.Chem_229_114095Discovery of novel beta-carboline derivatives as selective AChE inhibitors with GSK-3beta inhibitory property for the treatment of Alzheimer's disease
Liu_2021_Eur.J.Pharm.Sci__105976Novel chrysin derivatives as hidden multifunctional agents for anti-Alzheimer's disease: design, synthesis and in vitro evaluation
Liu_2021_Food.Funct_12_144Isoleucine increases muscle mass through promoting myogenesis and intramyocellular fat deposition
Liu_2021_Food.Funct__Phlorizin exerts potent effects against aging induced by D-galactose in mice and PC12 cells
Liu_2021_Front.Bioeng.Biotechnol_9_697677Enhanced Production of (S)-2-arylpropionic Acids by Protein Engineering and Whole-Cell Catalysis
Liu_2021_Front.Cell.Dev.Biol_9_640867Inhibiting Monoacylglycerol Lipase Suppresses RANKL-Induced Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss
Liu_2021_Front.Neural.Circuits_15_638000Excitatory Impact of Dental Occlusion on Dorsal Motor Nucleus of Vagus
Liu_2021_Front.Pharmacol_12_794933The Mechanisms of Cucurbitacin E as a Neuroprotective and Memory-Enhancing Agent in a Cerebral Hypoperfusion Rat Model: Attenuation of Oxidative Stress, Inflammation, and Excitotoxicity
Liu_2021_Front.Pharmacol_12_818907Rivastigmine Regulates the HIF-1alpha/VEGF Signaling Pathway to Induce Angiogenesis and Improves the Survival of Random Flaps in Rats
Liu_2021_Front.Plant.Sci_12_720816Insecticidal Terpenes From the Essential Oils of Artemisia nakaii and Their Inhibitory Effects on Acetylcholinesterase
Liu_2021_Gastroenterology.Res_14_157Efficacy and Safety of Neostigmine and Decompressive Colonoscopy for Acute Colonic Pseudo-Obstruction: A Single-Center Analysis
Liu_2021_Handb.Clin.Neurol_179_175The diagonal band of Broca in health and disease
Liu_2021_Int.J.Mol.Sci_22_Association of TaD14-4D, a Gene Involved in Strigolactone Signaling, with Yield Contributing Traits in Wheat
Liu_2021_J.Biosci.Bioeng_131_225Selecting cells expressing high levels of recombinant proteins using the GPI-anchored protein with selenocysteine system
Liu_2021_J.Endocrinol_248_133Combined use of GABA and sitagliptin promotes human beta-cell proliferation and reduces apoptosis
Liu_2021_J.Med.Chem_64_13853Blood-Brain Barrier Permeable and NO-Releasing Multifunctional Nanoparticles for Alzheimer's Disease Treatment: Targeting NO/cGMP/CREB Signaling Pathways
Liu_2021_J.Nat.Med__Stilbenoids isolated from the roots of Rheum lhasaense under the guidance of the acetylcholinesterase inhibition activity
Liu_2021_J.Org.Chem__One-Step Synthesis of 4-Octyl Itaconate through the Structure Control of Lipase
Liu_2021_J.Pharm.Sci__Characterization of Polysorbate 80 by Liquid Chromatography-Mass Spectrometry to Understand Its Susceptibility to Degradation and Its Oxidative Degradation Pathway
Liu_2021_Mol.Immunol_140_70Trelagliptin ameliorates IL-1beta-impaired chondrocyte function via the AMPK/SOX-9 pathway
Liu_2021_Mol.Pharmacol__Tacrine induces endoplasmic reticulum-stressed apoptosis via disrupting the proper assembly of oligomeric acetylcholinesterase in cultured neuronal cells
Liu_2021_Mol.Pharmacol__2Construction and characterization of CRISPR/Cas9 knockout rat model of carboxylesterase 2a gene
Liu_2021_Molecules_26_Discovery of Guanidine Derivatives from Buthus martensii Karsch with Metal-Binding and Cholinesterase Inhibition Properties
Liu_2021_Nanoscale__Red-to-blue paper-based colorimetric sensor integrated with smartphone for point-of-use analysis of cerebral AChE upon Cd(2+) exposure
Liu_2021_Nat.Prod.Res__1Two new organic acids from Portulaca oleracea L. and their anti-inflammatory and anticholinesterase activities
Liu_2021_Neurotoxicol_82_82Dose- and time-related effects of acute diisopropylfluorophosphate intoxication on forced swim behavior and sucrose preference in rats
Liu_2021_Parasit.Vectors_14_450In vitro and in vivo efficacy of thiacloprid against Echinococcus multilocularis
Liu_2021_Pharmgenomics.Pers.Med_14_477The Impact of ABCB1 and CES1 Polymorphisms on Dabigatran Pharmacokinetics in Healthy Chinese Subjects
Liu_2021_Plant.Cell__An ABHD17-like hydrolase screening system to identify de-S-acylation enzymes of protein substrates in plant cells
Liu_2021_Plant.Foods.Hum.Nutr_76_105Chemical Constituents and their Antioxidant, Anti-Inflammatory and Anti-Acetylcholinesterase Activities from Pholidota cantonensis
Liu_2021_Plant.Foods.Hum.Nutr__Elsholtzia rugulosa: Phytochemical Profile and Antioxidant, Anti-Alzheimer's Disease, Antidiabetic, Antibacterial, Cytotoxic and Hepatoprotective Activities
Liu_2021_Rev.Esp.Enferm.Dig_113_524High expression of NDRG3 correlates with poor prognosis in gastric cancer patients
Liu_2021_Sci.Total.Environ__150681Avobenzone and nanoplastics affect the development of zebrafish nervous system and retinal system and inhibit their locomotor behavior
Liu_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc__120665Monitoring of parathion methyl using a colorimetric gold nanoparticle-based acetylcholinesterase assay
Liu_2021_Toxins.(Basel)_13_874FumDSB Can Reduce the Toxic Effects of Fumonisin B(1) by Regulating Several Brain-Gut Peptides in Both the Hypothalamus and Jejunum of Growing Pigs
Lizama_2021_Antioxidants.(Basel)_10_Analysis of Carotenoids in Haloarchaea Species from Atacama Saline Lakes by High Resolution UHPLC-Q-Orbitrap-Mass Spectrometry: Antioxidant Potential and Biological Effect on Cell Viability
Lleo_2021_Alzheimers.Res.Ther_13_119VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome
Lobine_2021_Chem.Biodivers__Chemical Composition and Pharmacological Evaluation and of Toddalia asiatica (Rutaceae) Extracts and Essential Oil by in Vitro and in Silico Approaches
Loganathan_2021_Neurotoxicol__Astaxanthin-s-allyl cysteine diester against high glucose-induced neuronal toxicity in vitro and diabetes-associated cognitive decline in vivo: Effect on p53, oxidative stress and mitochondrial function
Loh_2021_J.Enzyme.Inhib.Med.Chem_36_627New 3-O-substituted xanthone derivatives as promising acetylcholinesterase inhibitors
Long_2021_Mar.Drugs_19_Cyclic Peptides from the Soft Coral-Derived Fungus Aspergillus sclerotiorum SCSIO 41031
Lopa_2021_Int.J.Food.Sci_2021_8862025Phytochemical Analysis and Cholinesterase Inhibitory and Antioxidant Activities of Enhydra fluctuans Relevant in the Management of Alzheimer's Disease
Lopes_2021_Chem.Biol.Drug.Des__Histamine H(3) receptor and cholinesterases as synergistic targets for cognitive decline: strategies to the rational design of multitarget ligands
Lopes_2021_RSC.Med.Chem_12_2001An overview on the synthesis of carbohydrate-based molecules with biological activity related to neurodegenerative diseases
Lopez-Canoa_2021_Europace_23_682Sex-related differences of fatty acid-binding protein 4 and leptin levels in atrial fibrillation
Lopez-Obando_2021_Plant.Cell__The Physcomitrium (Physcomitrella) patens PpKAI2L receptors for strigolactones and related compounds function via MAX2-dependent and independent pathways
Lopez_2021_Food.Funct__Neuroprotective and anxiolytic potential of green rooibos (Aspalathus linearis) polyphenolic extract
Lopez_2021_J.Venom.Anim.Toxins.Incl.Trop.Dis_27_e20210009Neuroactive venom compounds obtained from Phlogiellus bundokalbo as potential leads for neurodegenerative diseases: insights on their acetylcholinesterase and beta-secretase inhibitory activities in vitro
Lorke_2021_Int.J.Mol.Sci_22_Experimental and Established Oximes as Pretreatment before Acute Exposure to Azinphos-Methyl
Lourido_2021_Environ.Toxicol.Pharmacol__103783Lethal and sublethal effects of the emerging contaminant oxytetracycline on the embryo-larval development of Rhinella arenarum
Loving_2021_Cells_10_Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation
Lozano_2021_Sci.Total.Environ_800_149515Ivermectin: A multilevel approach to evaluate effects in Prochilodus lineatus (Valenciennes, 1836) (Characiformes, Prochilodontidae), an inland fishery species
Lu_2021_Biorxiv__Deep learning redesign of PETase for practical PET degrading applications
Lu_2021_Food.Sci.Nutr_9_2402The seed oil of Paeonia ludlowii ameliorates Abeta25-35-induced Alzheimer's disease in rats
Lu_2021_Front.Pharmacol_12_706762Gender Disparities in Anti-dementia Medication Use among Older Adults: Health Equity Considerations and Management of Alzheimer's Disease and Related Dementias
Lu_2021_Future.Med.Chem_13_1105Synthesis and activity of miconazole derivatives as dual BChE/IDO1 inhibitors for the treatment of Alzheimer's disease
Lu_2021_Future.Med.Chem_13_769Discovery, biological evaluation and molecular dynamic simulations of butyrylcholinesterase inhibitors through structure-based pharmacophore virtual screening
Lu_2021_Genes.(Basel)_12_E122A Novel Carboxylesterase Derived from a Compost Metagenome Exhibiting High Stability and Activity towards High Salinity
Lu_2021_Pestic.Biochem.Physiol_173_104800Activation of the NR2E nuclear receptor HR83 leads to metabolic detoxification-mediated chlorpyrifos resistance in Nilaparvata lugens
Lu_2021_Vet.Res_52_3Protection studies of an excretory-secretory protein HcABHD against Haemonchus contortus infection
Luan_2021_Ecotoxicol.Environ.Saf_220_112398Toxicologic effect and transcriptome analysis for short-term orally dosed enrofloxacin combined with two veterinary antimicrobials on rat liver
Lubbers_2021_Microb.Cell.Fact_20_151Vanillic acid and methoxyhydroquinone production from guaiacyl units and related aromatic compounds using Aspergillus niger cell factories
Luca_2021_Antioxidants.(Basel)_10_Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the Genus Piper
Luedtke_2021_Crystals_11_1270Backbone Conformation Shifts in X-ray Structures of Human Acetylcholinesterase upon Covalent Organophosphate Inhibition
Luis_2021_J.Nanobiotechnology_19_163Ecotoxicity evaluation of polymeric nanoparticles loaded with ascorbic acid for fish nutrition in aquaculture
Lukawski_2021_Pol.J.Vet.Sci_24_211Neurological effects of acute exposure to caffeine and organophosphates in mice
Lum_2021_ACS.Chem.Neurosci__Protective Effect of Natural Products against Huntington's Disease: An Overview of Scientific Evidence and Understanding Their Mechanism of Action
Lumley_2021_Toxicol.Rep_8_896Soman-induced toxicity, cholinesterase inhibition and neuropathology in adult male Gttingen minipigs
Lund_2021_Molecules_26_7155ThermoSlope: A Software for Determining Thermodynamic Parameters from Single Steady-State Experiments
Lunguinho_2021_Vet.Parasitol_300_109594Acaricidal and repellent activity of the essential oils of Backhousia citriodora, Callistemon viminalis and Cinnamodendron dinisii against Rhipicephalus spp
Luo_2021_Aging.(Albany.NY)_13_20179Long non-coding RNA ABHD11-AS1 promotes colorectal cancer progression and invasion through targeting the integrin subunit alpha 5/focal adhesion kinase/phosphoinositide 3 kinase/Akt signaling pathway
Luo_2021_Anal.Chem__Iridium Single-Atomic Site Catalysts with Superior Oxygen Reduction Reaction Activity for Sensitive Monitoring of Organophosphorus Pesticides
Luo_2021_Front.Cell.Dev.Biol_8_620543Non-neuronal Role of Acetylcholinesterase in Bone Development and Degeneration
Luo_2021_Front.Mol.Neurosci_14_744845Postsynaptic Neuroligin-1 Mediates Presynaptic Endocytosis During Neuronal Activity
Luo_2021_Front.Pediatr_9_679342Mechanisms of Congenital Myasthenia Caused by Three Mutations in the COLQ Gene
Luo_2021_J.Biol.Chem__100667Inhibition of soluble epoxide hydrolase alleviates insulin resistance and hypertension via downregulation of SGLT2 in the mouse kidney
Luo_2021_Neuropharmacol_195_108675Delta-containing GABA(A) receptors in pain management: Promising targets for novel analgesics
Luo_2021_Technol.Cancer.Res.Treat_20_15330338211033074MiR-188-3p and miR-133b Suppress Cell Proliferation in Human Hepatocellular Carcinoma via Post-Transcriptional Suppression of NDRG1
Lupi_2021_Insects_12_Combined Effects of Pesticides and Electromagnetic-Fields on Honeybees: Multi-Stress Exposure
Luther_2021_Hypertension_78_1092GSK2256294 Decreases sEH (Soluble Epoxide Hydrolase) Activity in Plasma, Muscle, and Adipose and Reduces F2-Isoprostanes but Does Not Alter Insulin Sensitivity in Humans
Luz_2021_An.Acad.Bras.Cienc_93_e20190672Lipase production by microorganisms isolated from the Serra de Ouro Branco State Park
Lv_2021_BMC.Plant.Biol_21_501Genome-wide identification of the tobacco GDSL family and apical meristem-specific expression conferred by the GDSL promoter
Lv_2021_Environ.Pollut_280_117000Molecular response uncovers neurotoxicity of Pardosa pseudoannulata exposed to cadmium pressure
Lv_2021_Int.J.Biol.Macromol_167_1262Investigation of the inhibitory effect of protostanes on human carboxylesterase 2 and their interaction: Inhibition kinetics and molecular stimulations
Lyagin_2021_Int.J.Mol.Sci_22_Enzymes, Reacting with Organophosphorus Compounds as Detoxifiers: Diversity and Functions
Lyczko_2021_Microb.Biotechnol__The catalytic activity of mycelial fungi towards 7-oxo-DHEA - an endogenous derivative of steroidal hormone dehydroepiandrosterone
Lyu_2021_BMJ.Open_11_e048453Effect of antiamyloid-beta drugs on Alzheimer's disease: study protocol for a systematic review and meta-analysis
Ma_2021_Ann.Palliat.Med__Comparison of four markers of hepatic fibrosis and hepatic function indices in patients with liver cirrhosis and hepatoma
Ma_2021_Biomed.Chromatogr__e5077Dynamic changes in chemical compositions and anti-acetylcholinesterase activity associated with steaming process of stem-leaf saponins of Panax notoginseng
Ma_2021_Chin.J.Integr.Med_27_912Elemene Emulsion Injection Administration Reduces Neuropathic Pain by Inhibiting Astrocytic NDRG2 Expression within Spinal Dorsal Horn
Ma_2021_Environ.Microbiol_23_996An ultrahigh-throughput screening platform based on flow cytometric droplet sorting for mining novel enzymes from metagenomic libraries
Ma_2021_Insect.Mol.Biol__Juvenile hormone regulates the reproductive diapause through Methoprene-tolerant gene in Galeruca daurica
Ma_2021_J.Agric.Food.Chem__Design, Synthesis, and Study of the Insecticidal Activity of Novel Steroidal 1,3,4-Oxadiazoles
Ma_2021_Mikrochim.Acta_188_294Ratiometric sensing of butyrylcholinesterase activity based on the MnO(2) nanosheet-modulated fluorescence of sulfur quantum dots and o-phenylenediamine
Ma_2021_Mikrochim.Acta_188_392Point-of-care testing of butyrylcholinesterase activity through modulating the photothermal effect of cuprous oxide nanoparticles
Ma_2021_Mol.Immunol_141_108The protective effects of Omarigliptin against Lipopolysaccharide (LPS)- induced inflammatory response and expression of mucin 5AC (MUC5AC) in human bronchial epithelial cells
Ma_2021_Talanta_235_122798Magnetic covalent organic framework immobilized gold nanoparticles with high-efficiency catalytic performance for chemiluminescent detection of pesticide triazophos
Maafi_2021_Bioorg.Med.Chem.Lett_51_128374Derivatives of montanine-type alkaloids and their implication for the treatment of Alzheimer's disease: Synthesis, biological activity and in silico study
MacCormack_2021_Front.Bioeng.Biotechnol_9_689933Boron Oxide Nanoparticles Exhibit Minor, Species-Specific Acute Toxicity to North-Temperate and Amazonian Freshwater Fishes
Machado_2021_Nutr.Neurosci_24_697Ilex paraguariensis extract provides increased resistance against oxidative stress and protection against Amyloid beta-induced toxicity compared to caffeine in Caenorhabditis elegans
Macharoen_2021_Biotechnol.Bioeng_118_1431Production of recombinant butyrylcholinesterase from transgenic rice cell suspension cultures in a pilot-scale bioreactor
Macht_2021_J.Neuroinflammation_18_212Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure
Madacki_2021_Int.J.Mol.Sci_22_Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives
Madboli_2021_Environ.Sci.Pollut.Res.Int__Immunohistochemical, histopathological, and biochemical studies of the NF-kappaB P65 marker in rat ovaries experimentally intoxicated by cadmium and the protective effect of the purslane plant extract
Maezawa_2021_J.Vet.Med.Sci__Acute myelomonocytic leukemia negative for alpha-naphthyl acetate esterase stain in a Holstein cow
Mafa_2021_AMB.Express_11_21Feruloyl esterase (FAE-1) sourced from a termite hindgut and GH10 xylanases synergy improves degradation of arabinoxylan
Magalhaes-Gomes_2021_Neurosci__Increasead cholinergic tone causes pre-synaptic neuromuscular degeneration and is associated with impaired diaphragm function
Magalhaes_2021_Int.J.Mol.Sci_22_11257Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET
Magar_2021_Int.J.Mol.Sci_22_Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE
Maggio_2021_Chemosphere_276_130120Neurotoxicity of chlorpyrifos and chlorpyrifos-oxon to Daphnia magna
Maglioni_2021_Cells_11_High-Content C. elegans Screen Identifies Natural Compounds Impacting Mitochondria-Lipid Homeostasis and Promoting Healthspan
Mahe_2021_Environ.Res__110784The countryside or the city: which environment is better for the honeybee?
Mahnashi_2021_BMC.Complement.Med.Ther_21_248Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches
Mahomoodally_2021_Antibiotics.(Basel)_10_Pharmacological Potential and Chemical Characterization of Bridelia ferruginea Benth.-A Native Tropical African Medicinal Plant
Mahomoodally_2021_Curr.Med.Chem_28_4638Conventional and Non-Conventional Targets of Natural Products in the Management of Diabetes Mellitus and Associated Complications
Maiangwa_2021_J.Mol.Graph.Model_105_107897Enhancing the stability of Geobacillus zalihae T1 lipase in organic solvents and insights into the structural stability of its variants
Maity_2021_Appl.Biochem.Biotechnol_193_2699Emerging Roles of PETase and MHETase in the Biodegradation of Plastic Wastes
Majrashi_2021_J.Integr.Neurosci_20_321beta-hydroxybutyric acid attenuates oxidative stress and improves markers of mitochondrial function in the HT-22 hippocampal cell line
Majumdar_2021_Front.Plant.Sci_12_780877Regulatory Roles of Small Non-coding RNAs in Sugar Beet Resistance Against Beet curly top virus
Mak_2021_J.Neurochem__Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget
Makhaeva_2021_Bioorg.Chem_112_104974Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment
Makhaeva_2021_Eur.J.Med.Chem_218_113385Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold
Maki-Petaja_2021_Hypertension__HYPERTENSIONAHA12016454Mechanisms Underlying Vascular Endothelial Growth Factor Receptor Inhibition-Induced Hypertension: The HYPAZ Trial
Maksimovic_2021_Drug.Chem.Toxicol__1Acute organophosphate and carbamate pesticide poisonings - a five-year survey from the National Poison Control Center Of Serbia
Malafaia_2021_Int.J.Mol.Sci_22_Chromeno[3,4-b]xanthones as First-in-Class AChE and Abeta Aggregation Dual-Inhibitors
Malafaia_2021_J.Hazard.Mater__127873Shedding light on the impacts of gestational exposure to polystyrene nanoplastics on the reproductive performance of Poecilia reticulata female and on the biochemical response of embryos
Malafaia_2021_Sci.Total.Environ_783_146994Green toxicology approach involving polylactic acid biomicroplastics and neotropical tadpoles: (Eco)toxicological safety or environmental hazard?
Malamas_2021_ChemMedChem__Design and Synthesis of Highly Potent and Specific ABHD6 Inhibitors
Maleki_2021_Bioorg.Chem_109_104684Design and synthesis of new carbamates as inhibitors for fatty acid amide hydrolase and cholinesterases: Molecular dynamic, in vitro and in vivo studies
Malgas_2021_Molecules_26_Unraveling Synergism between Various GH Family Xylanases and Debranching Enzymes during Hetero-Xylan Degradation
Malik_2021_Mol.Divers__ABCpred: a webserver for the discovery of acetyl- and butyryl-cholinesterase inhibitors
Maliszewski_2021_Molecules_26_1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors
Mamun_2021_Int.J.Mol.Sci_22_Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies
Manayi_2021_Nat.Prod.Res__1Phytochemical investigation and biological activity of Doronicum pardalianches L. roots against Alzheimer's disease
Mandic_2021_PLoS.One_16_e0246810Chemical characterization and in vitro immunomodulatory effects of different extracts of moss Hedwigia ciliata (Hedw.) P. Beauv. from the Vrake Planine Mts., Serbia
Mandour_2021_J.Mol.Histol__Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid hesperidin
Manfo_2021_Toxicol.Res.(Camb)_10_232Occupational use of agrochemicals results in inhibited cholinesterase activity and altered reproductive hormone levels in male farmers from Buea, Cameroon
Mang'era_2021_Parasit.Vectors_14_1Transcriptomic response of Anopheles gambiae sensu stricto mosquito larvae to Curry tree (Murraya koenigii) phytochemicals
Mangiagalli_2021_Int.J.Biol.Macromol_181_263The activity and stability of a cold-active acylaminoacyl peptidase rely on its dimerization by domain swapping
Mangmool_2021_Molecules_26_Antioxidant and Anticholinesterase Activities of Extracts and Phytochemicals of Syzygium antisepticum Leaves
Manickam_2021_Arch.Pharm.(Weinheim)__e2100367Activating endogenous resolution pathways by soluble epoxide hydrolase inhibitors for the management of COVID-19
Manikandan_2021_Int.J.Fertil.Steril_15_219Assessment of Organophosphate Pesticides Exposure in Men with Idiopathic Abnormal Semen Analysis: A Cross-Sectional Pilot Study
Mansinhos_2021_Antioxidants.(Basel)_10_Ultrasonic-Assisted Extraction and Natural Deep Eutectic Solvents Combination: A Green Strategy to Improve the Recovery of Phenolic Compounds from Lavandula pedunculata subsp. lusitanica (Chaytor) Franco
Manzoor_2021_Bioorg.Chem_116_105354Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer's disease
Manzoor_2021_Eur.J.Med.Chem_215_113224Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation
Marasco_2021_Chem.Biol.Interact_334_109300Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on beta-amyloid aggregation
Margus_2021_Ecol.Evol_11_15995Sequence variation and regulatory variation in acetylcholinesterase genes contribute to insecticide resistance in different populations of Leptinotarsa decemlineata
Marikova_2021_Molecules_26_Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids
Marinho_2021_Fish.Physiol.Biochem__Toxicity of silver nanoparticles on different tissues in adult Danio rerio
Marins_2021_Ecotoxicology_30_164A mixture of pesticides at environmental concentrations induces oxidative stress and cholinergic effects in the neotropical fish Rhamdia quelen
Marins_2021_Ecotoxicology__Environmentally relevant pesticides induce biochemical changes in Nile tilapia (Oreochromis niloticus)
Markova_2021_ACS.Catal_11_12864Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers
Markova_2021_Toxics_9_Synthesis and Decontamination Effect on Chemical and Biological Agents of Benzoxonium-Like Salts
Marques_2021_ACS.Appl.Bio.Mater_4_8456Dip-and-Fold Device: A Paper-Based Testing Platform for Rapid Assessment of Insecticides in Water Samples
Marques_2021_Curr.Opin.Struct.Biol_69_19Web-based tools for computational enzyme design
Marrero-Rosado_2021_Int.J.Mol.Sci_22_Novel Genetically Modified Mouse Model to Assess Soman-Induced Toxicity and Medical Countermeasure Efficacy: Human Acetylcholinesterase Knock-in Serum Carboxylesterase Knockout Mice
Marsillach_2021_Antioxidants.(Basel)_10_Paraoxonase-1 and Other HDL Accessory Proteins in Neurological Diseases
Martelli_2021_Front.Genet_12_720552hGATA1 Under the Control of a LCR/beta-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced by the Gata1 (low) Mutation in Mice
Martin-Lopez_2021_Pharmaceuticals.(Basel)_14_2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity
Martin-Reina_2021_Int.J.Environ.Res.Public.Health_18_Adverse Health Effects in Women Farmers Indirectly Exposed to Pesticides
Martinez-Alvarez_2021_Sci.Total.Environ_775_145669Uptake and effects of graphene oxide nanomaterials alone and in combination with polycyclic aromatic hydrocarbons in zebrafish
Martinez-Galan_2021_Food.Res.Int_148_110602Enzymatic synthesis of capric acid-rich structured lipids and their effects on mice with high-fat diet-induced obesity
Martinez_2021_Environ.Sci.Pollut.Res.Int__Comparison of biomarker responses after acute and chronic bioassays in Lumbriculus variegatus
Martini_2021_Neurocrit.Care__A Double-Blind, Randomized, Placebo-Controlled Trial of Soluble Epoxide Hydrolase Inhibition in Patients with Aneurysmal Subarachnoid Hemorrhage
Martins_2021_Clin.Biochem_89_63Increased oxidative stress and inflammatory markers contrasting with the activation of the cholinergic anti-inflammatory pathway in patients with metabolic syndrome
Martins_2021_Prep.Biochem.Biotechnol__1Solid-state fermentation production and characterization of an alkaline lipase from a newly isolated Burkholderia gladioli strain
Martins_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_252_119511Impact on cholinesterase-inhibition and in silico investigations of sesquiterpenoids from Amazonian Siparuna guianensis Aubl
Maruszewska-Cheruiyot_2021_Parasit.Vectors_14_106The production of excretory-secretory molecules from Heligmosomoides polygyrus bakeri fourth stage larvae varies between mixed and single sex cultures
Marzoughi_2021_J.Neurochem_158_1334Tardive neurotoxicity of anticholinergic drugs: A review
Masaryk_2021_Dalton.Trans__Unexpected solution behaviour of ester-functionalized half-sandwich Ru(II) and Ir(III) complexes
Mascarenhas_2021_Rev.Esp.Enferm.Dig_113_551Gastric caustic injury after organophosphate poisoning
Mashayekhi_2021_Prostaglandins.Other.Lipid.Mediat_158_106604The soluble epoxide hydrolase inhibitor GSK2256294 decreases the proportion of adipose pro-inflammatory T cells
Mashimo_2021_Int.J.Mol.Sci_22_Regulation of Immune Functions by Non-Neuronal Acetylcholine (ACh) via Muscarinic and Nicotinic ACh Receptors
Masi_2021_Biomolecules_11_Isolation and Biological Characterization of Homoisoflavanoids and the Alkylamide N-p-Coumaroyltyramine from Crinum biflorum Rottb., an Amaryllidaceae Species Collected in Senegal
Maslennikov_2021_World.J.Hepatol_13_557Gut dysbiosis is associated with poorer long-term prognosis in cirrhosis
Masurkar_2021_Drugs.Aging__Antimuscarinic Cascade Across Individual Cholinesterase Inhibitors in Older Adults with Dementia
Masurkar_2021_J.Am.Geriatr.Soc__Risk of overactive bladder associated with cholinesterase inhibitors in dementia
Matabaro_2021_Methods.Enzymol_656_429Enzyme-mediated backbone N-methylation in ribosomally encoded peptides
Matabaro_2021_Sci.Rep_11_3541Identification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A
Matheson_2021_Pharmaceuticals.(Basel)_14_Potential of Fatty Acid Amide Hydrolase (FAAH), Monoacylglycerol Lipase (MAGL), and Diacylglycerol Lipase (DAGL) Enzymes as Targets for Obesity Treatment: A Narrative Review
Mathew_2021_Environ.Sci.Pollut.Res.Int__1Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders
Mathimaran_2021_Biogerontology_22_19Partially saturated canthaxanthin alleviates aging-associated oxidative stress in D-galactose administered male wistar rats
Matosevic_2021_Pharmaceutics_13_Quinuclidine-Based Carbamates as Potential CNS Active Compounds
Matsushita_2021_Chem.Res.Toxicol__Metabolism-Coupled Cell-Independent Acetylcholinesterase Activity Assay for Evaluation of the Effects of Chlorination on Diazinon Toxicity
Matzner_2021_J.Neurochem__Rhythmogenic networks are potently modulated by activation of muscarinic acetylcholine receptors in the rodent spinal cord
Maupu_2021_Neurobiol.Dis__105276Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice
Mavangira_2021_Antioxidants.(Basel)_10_Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis
Maxwell_2021_J.Clin.Psychopharmacol__Prolonged Paralysis After Electroconvulsive Therapy Due to Butyrylcholinesterase Gene Mutation
Maxwell_2021_Neurobiol.Aging_101_298 e1Clinical and neuropathological variability in the rare IVS10 + 14 tau mutation
Mayer_2021_Br.J.Pharmacol_178_878The dipeptidyl peptidase 4 inhibitor linagliptin ameliorates renal injury and accelerated resolution in a rat model of crescentic nephritis
Mayo_2021_Biol.Psychiatry__Targeting the Endocannabinoid System in the Treatment of Posttraumatic Stress Disorder: A Promising Case of Preclinical-Clinical Translation?
Mazej_2021_Molecules_26_4-Phenethyl-1-Propargylpiperidine-Derived Dual Inhibitors of Butyrylcholinesterase and Monoamine Oxidase B
Mazur_2021_Acta.Crystallogr.D.Struct.Biol_77_347The tetrameric structure of the novel haloalkane dehalogenase DpaA from Paraglaciecola agarilytica NO2
Mazur_2021_Int.J.Mol.Sci_22_11992Structural Analysis of the Ancestral Haloalkane Dehalogenase AncLinB-DmbA
McGregor_2021_J.Econ.Entomol_114_24Comparison of the Effect of Insecticides on Bumble Bees (Bombus impatiens) and Mosquitoes (Aedes aegypti and Culex quinquefasciatus) by Standard Mosquito Research Methods
McGuire_2021_Chem.Res.Toxicol__Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6
McReynolds_2021_Front.Physiol_12_663869Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections
McReynolds_2021_Molecules_26_Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development
Meads_2021_Toxicol.Appl.Pharmacol__115466Evaluation of adenosine A1 receptor agonists as neuroprotective countermeasures against Soman intoxication in rats
Medvedev_2021_J.Mol.Biol_433_166788A Fifth of the Protein World: Rossmann-like Proteins as an Evolutionarily Successful Structural unit
Meek_2021_Toxicol.In.Vitro__105102In vitro age-related differences in rats to organophosphates
Meek_2021_Toxicol.Sci__Inhibition Kinetics of 16 Organophosphorus Pesticides or Their Active Metabolites on Erythrocyte Acetylcholinesterase from Humans and Rats
Megighian_2021_J.Neurochem__Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets
Mehrabi_2021_Sci.Adv_7_eabf1380Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison
Meira_2021_ACS.Chem.Neurosci__Binding Mechanism between Acetylcholinesterase and Drugs Pazopanib and Lapatinib: Biochemical and Biophysical Studies
Melefa_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109108Imidazole antifungal drug clotrimazole alters the behavior, brain acetylcholinesterase and oxidative stress biomarkers in African catfish Clarias gariepinus (Burchell 1822)
Mella_2021_Nat.Prod.Res__1Acetylcholinesterase inhibitory activity from Amaryllis belladonna growing in Chile: enzymatic and molecular docking studies
Mello_2021_Cell.Mol.Gastroenterol.Hepatol_11_815Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease
Mendez-Alvarez_2021_Mol.Divers__Ligand-based virtual screening, molecular docking, and molecular dynamics of eugenol analogs as potential acetylcholinesterase inhibitors with biological activity against Spodoptera frugiperda
Mendonca-Gomes_2021_Environ.Pollut_289_117818Shedding light on toxicity of SARS-CoV-2 peptides in aquatic biota: A study involving neotropical mosquito larvae (Diptera: Culicidae)
Meng_2021_Biomed.Res.Int_2021_4579850A Network Pharmacology-Based Study on Irritable Bowel Syndrome Prevention and Treatment Utilizing Shenling Baizhu Powder
Meng_2021_Environ.Pollut__118333Multigenerational effects modify the tolerance of mosquito larvae to chlorpyrifos but not to a heat spike and do not change their synergism
Meng_2021_Int.J.Biol.Macromol_180_667Protein engineering of stable IsPETase for PET plastic degradation by Premuse
Meng_2021_Plant.J__KARRIKIN INSENSITIVE2 regulates leaf development, root system architecture and arbuscular-mycorrhizal symbiosis in Brachypodium distachyon
Menghini_2021_Biomolecules_11_Chemical and Bioinformatics Analyses of the Anti-Leishmanial and Anti-Oxidant Activities of Hemp Essential Oil
Mennillo_2021_Drug.Metab.Dispos__Intestinal UGT1A1 and protection against Irinotecan-induced toxicity in a novel UGT1A1 tissue-specific humanized mouse model
Menzel_2021_Polymers.(Basel)_13_Impact of Enzymatic Degradation on the Material Properties of Poly(Ethylene Terephthalate)
Messenger_2021_Insect.Biochem.Mol.Biol__103655A whole transcriptomic approach provides novel insights into the molecular basis of organophosphate and pyrethroid resistance in Anopheles arabiensis from Ethiopia
Metafuni_2021_Blood.Adv__Day100 Score predicts moderate-severe cGVHD, transplant mortality, and survival after hematopoietic cell transplantation
Metz_2021_J.Neurochem_158_1359Treating disorders across the lifespan by modulating cholinergic signaling with galantamine
Meyer-Cifuentes_2021_Front.Microbiol_12_693985Mle046 Is a Marine Mesophilic MHETase-Like Enzyme
Meyer_2021_Methods.Enzymol_648_47Exploring microbial consortia from various environments for plastic degradation
Mezeiova_2021_Bioorg.Med.Chem.Lett__128100Huprine Y - tryptophan heterodimers with potential implication to Alzheimer's disease treatment
Miao_2021_Front.Neurol_12_817896Clinical Features and Prognosis in Chinese Patients With Dipeptidyl-Peptidase-Like Protein 6 Antibody-Associated Encephalitis
Miao_2021_J.Nat.Prod_84_2374Pd-Catalyzed Direct Diversification of Natural Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of N-Aryl Huperzine A Analogues
Miceli_2021_Int.J.Mol.Sci_22_A New Ultrasensitive Bioluminescence-Based Method for Assaying Monoacylglycerol Lipase
Michalovicz_2021_Life.Sci__119962The beta-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness
Michels_2021_BMJ.Open_11_e042857Butyrylcholinesterase as a perioperative complication marker in patients after transcatheter aortic valve implantation: a prospective observational study
Miguel-Ruano_2021_Comput.Struct.Biotechnol.J_19_1214Biochemical and Structural Characterization of a novel thermophilic esterase EstD11 provide catalytic insights for the HSL family
Mihaylova_2021_Molecules_26_GC-MS Metabolic Profile and alpha-Glucosidase-, alpha-Amylase-, Lipase-, and Acetylcholinesterase-Inhibitory Activities of Eight Peach Varieties
Miklosz_2021_Biomolecules_11_Treadmill Running Changes Endothelial Lipase Expression: Insights from Gene and Protein Analysis in Various Striated Muscle Tissues and Serum
Milbocker_2021_Birth.Defects.Res_113_299Examination of cortically projecting cholinergic neurons following exercise and environmental intervention in a rodent model of fetal alcohol spectrum disorders
Milech_2021_Vet.Med.Int_2021_5515559Effects of Heated Pneumoperitoneum on Inflammation, Oxidative Stress, and Peritoneal Histology in Female Dogs That Underwent Video-Assisted Ovariohysterectomy
Milek_2021_Acta.Bioeng.Biomech_23_25The effect of pH on determination of activation energies and the optimum temperatures of hydrolysis of olive oil by lipase from porcine pancreas
Miles_2021_ACS.Chem.Neurosci_12_30Recent Advances in Virtual Screening for Cholinesterase Inhibitors
Miles_2021_Chem.Biol.Drug.Des__Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database
Milicevic_2021_Eur.J.Pharm.Sci__105757RETRACTED Development of a simple QSAR model for reliable evaluation of acetylcholinesterase inhibitor potency
Miller_2021_Elife_10_e66657Structure-guided microbial targeting of antistaphylococcal prodrugs
Millet_2021_Anaesth.Crit.Care.Pain.Med__100847Phenotype and genotype characteristics of 58 patients showing a prolonged effect of succinylcholine: a four-year experience
Min_2021_Bioresour.Technol_337_125394Improving the organic solvent resistance of lipase a from Bacillus subtilis in water-ethanol solvent through rational surface engineering
Min_2021_CNS.Neurosci.Ther__Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice
Min_2021_Life.(Basel)_11_A Novel Dipeptidyl Peptidase-4 Inhibitor DA-1229 Ameliorates Tubulointerstitial Fibrosis in Cyclosporine Nephrotoxicity in Mice
Minamihata_2021_Neurochem.Res__Increase in Cellular Lysophosphatidylserine Content Exacerbates Inflammatory Responses in LPS-Activated Microglia
Mintjens_2021_Acta.Anaesthesiologica.Scandinavica_65_182Timing of blood sampling for butyrylcholinesterase phenotyping in patients with prolonged neuromuscular block after mivacurium or suxamethonium
Miralpeix_2021_Br.J.Pharmacol_178_1507Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
Miro-Vinyals_2021_Chembiochem__HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridium Dye
Mirzazadeh_2021_Arch.Pharm.(Weinheim)__e2000471New quinoxalin-1,3,4-oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies
Miskovic_2021_Chem.Biodivers__Mushroom Species Stereum hirsutum as Natural Source of Phenolics and Fatty Acids as Antioxidants and Acetylcholinesterase Inhibitors
Miskovic_2021_J.Fungi.(Basel)_7_Comparison of Two Schizophyllum commune Strains in Production of Acetylcholinesterase Inhibitors and Antioxidants from Submerged Cultivation
Missoum_2021_Methods.Mol.Biol_2290_215Recombinant Protein Production and Purification Using Eukaryotic Cell Factories
Mit_2021_Sci.Total.Environ_773_144734Modeling acetylcholine esterase inhibition resulting from exposure to a mixture of atrazine and chlorpyrifos using a physiologically-based kinetic model in fish
Mitic_2021_Expert.Opin.Drug.Metab.Toxicol__Does the application of acetylcholinesterase inhibitors in the treatment of Alzheimer's disease lead to depression?
Mito_2021_Intern.Med_60_1145Influence of Serum Cholinesterase Levels on Patients Suspected of Having Stable Coronary Artery Disease
Mitra_2021_Addict.Biol__e13007A role for the endocannabinoid enzymes monoacylglycerol and diacylglycerol lipases in cue-induced cocaine craving following prolonged abstinence
Mitra_2021_Front.Aging.Neurosci_13_714186Increased Endogenous GDNF in Mice Protects Against Age-Related Decline in Neuronal Cholinergic Markers
Mitric_2021_Bull.Environ.Contam.Toxicol__Sampling Site Specific Biomarker Responses in Mediterranean Mussels from the Adriatic Sea
Miyake_2021_Clin.Genet__A homozygous ABHD16A variant causes a complex hereditary spastic paraplegia with developmental delay, absent speech, and characteristic face
Miziak_2021_Expert.Opin.Drug.Discov_16_579Advances in the design and discovery of novel small molecule drugs for the treatment of Dravet Syndrome
Miziak_2021_Pharmaceuticals.(Basel)_14_Some Candidate Drugs for Pharmacotherapy of Alzheimer's Disease
Mizutani_2021_Mol.Cell.Neurosci_115_103653Nectins and Nectin-like molecules in synapse formation and involvement in neurological diseases
Mladenova_2021_Int.J.Mol.Sci_22_A Galantamine-Curcumin Hybrid Decreases the Cytotoxicity of Amyloid-Beta Peptide on SH-SY5Y Cells
Mlakic_2021_Pharmaceuticals.(Basel)_14_New Uncharged 2-Thienostilbene Oximes as Reactivators of Organophosphate-Inhibited Cholinesterases
Mo_2021_Environ.Pollut_291_118120Adsorption mechanism of two pesticides on polyethylene and polypropylene microplastics: DFT calculations and particle size effects
Modoni_2021_Clin.Neurophysiol_132_1845Cholinergic hyperactivity in patients with myasthenia gravis with MuSK antibodies: A neurophysiological study
Moecking_2021_J.Allergy.Clin.Immunol_147_2134NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity
Moghadam_2021_J.Mol.Graph.Model_107_107981Computational evidence of new putative allosteric sites in the acetylcholinesterase receptor
Mohamed_2021_BMJ.Case.Rep_14_Anaesthetic management of a patient with eosinophilic granulomatosis with polyangiitis for internal fixation of a fractured femur
Mohamed_2021_J.Food.Biochem__e13715Alleviation of fructose-induced Alzheimer's disease in rats by pioglitazone and decaffeinated green coffee bean extract
Mohammadi-Farani_2021_Behav.Pharmacol__Sodium butyrate enhances fear extinction and rescues hippocampal acetylcholinesterase activity in a rat model of posttraumatic stress disorder
Mohammadi_2021_Comp.Immunol.Microbiol.Infect.Dis_76_101642Evaluation of some acute phase proteins in cattle naturally infected with Babesia bigemina
Mohammed_2021_Lasers.Med.Sci__Antidepressant and antioxidant effects of transcranial irradiation with 830-nm low-power laser in an animal model of depression
Mohammed_2021_Life.Sci_273_119303Electrophysiological and neurochemical evaluation of the adverse effects of REM sleep deprivation and epileptic seizures on rat's brain
Mohd Din_2021_Catalysts_11_244Heterologous Expression and Characterization of Plant Lipase LIP2 from Elaeis guineensis Jacq. Oil Palm Mesocarp in Escherichia coli
Mok_2021_Polymers.(Basel)_13_In Vivo Characterization and Application of the PHA Synthase from Azotobacter vinelandii for the Biosynthesis of Polyhydroxyalkanoate Containing 4-Hydroxybutyrate
Mokhtar_2021_Int.J.Biol.Macromol__Extraction and reimmobilization of used commercial lipase from industrial waste
Mokkapati_2021_Ecotoxicol.Environ.Saf_230_113095Physiological and biochemical response of the solitary bee Osmia bicornis exposed to three insecticide-based agrochemicals
Moleda_2021_Bioorg.Med.Chem_42_116269Clicking fragment leads to novel dual-binding cholinesterase inhibitors
Molina-Gutierrez_2021_J.Agric.Food.Chem_69_286Sustainable and Green Synthesis of Stanol Esters from Oil Wastes
Moncaleano-Nino_2021_Environ.Sci.Pollut.Res.Int__Monitoring metallothionein-like protein concentrations and cholinesterase activity in tropical cup oysters as biomarkers of exposure to metals and pesticides in the southern Caribbean, Colombia
Monroy-Noyola_2021_Chem.Biol.Interact__109524DAEH N-terminal sequence of avian serum albumins as catalytic center of Cu (II)-dependent organophosphorus hydrolyzing A-esterase activity
Monroy-Noyola_2021_Front.Biosci.(Landmark.Ed)_26_744Hydrolysis of chiral organophosphorus compounds by phosphotriesterases and mammalian paraoxonase-1
Montana_2021_Healthcare.(Basel)_9_A Rare Case of Suicide by Ingestion of Phorate: A Case Report and a Review of the Literature
Montanari_2021_Molecules_26_3254New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators
Monteiro_2021_Catal.Today_362_141Biotechnological relevance of the lipase A from Candida antarctica
Moo_2021_Clin.Ther__Unexpected Findings During Double-blind Discontinuation of Acetylcholinesterase Inhibitor Medications
Moog_2021_Methods.Enzymol_648_435Engineering microalgae as a whole cell catalyst for PET degradation
Mooko_2021_Endocr.Metab.Immune.Disord.Drug.Targets__Cannabis Sativa L. Flower and Bud Extracts inhibited In vitro Cholinesterases and b-Secretase Enzymes Activities: Possible Mechanisms of Cannabis use in Alzheimer Disease
Mooney-Leber_2021_Front.Psychiatry_12_737897Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains
Moreira_2021_Food.Chem_367_130728Chemometric evaluation of enzymatic hydrolysis in the production of fish protein hydrolysates with acetylcholinesterase inhibitory activity
Morena_2021_Br.J.Pharmacol_178_983Sex-dependent effects of endocannabinoid modulation of conditioned fear extinction in rats
Moreno-Luna_2021_Mol.Neurobiol_58_689Heterogeneity of the Endocannabinoid System Between Cerebral Cortex and Spinal Cord Oligodendrocytes
Moreta_2021_Biomedicines_9_Efficacy of Acetylcholinesterase Inhibitors on Cognitive Function in Alzheimer's Disease. Review of Reviews
Moricz_2021_J.Chromatogr.A_1635_461727Bioactive clerodane diterpenes of giant goldenrod (Solidago gigantea Ait.) root extract
Moricz_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1185_123004Acetylcholinesterase inhibitors in the giant goldenrod root
Morigny_2021_J.Cachexia.Sarcopenia.Muscle_12_1333Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy
Moriou_2021_Mar.Drugs_19_Bioactive Bromotyrosine Derivatives from the Pacific Marine Sponge Suberea clavata (Pulitzer-Finali, 1982)
Morisseau_2021_Int.J.Mol.Sci_22_Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues
Morlock_2021_Antioxidants.(Basel)_10_Effect-Directed Profiling of Powdered Tea Extracts for Catechins, Theaflavins, Flavonols and Caffeine
Morozov_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109240Biochemical and respiratory parameters in a gastropod Radix balthica exposed to diclofenac
Morris_2021_J.Alzheimers.Dis__The Association Between Use of Rivastigmine and Pneumonia: Systematic Analysis of FDA Adverse Event Reporting System
Morris_2021_J.Alzheimers.Dis__2Bradycardia Due to Donepezil in Adults: Systematic Analysis of FDA Adverse Event Reporting System
Moss_2021_Curr.Alzheimer.Res__Anti-neurodegenerative benefits of acetylcholinesterase inhibitors in Alzheimer's disease: Nexus of cholinergic and nerve growth factor dysfunction
Mostafa_2021_Antioxidants.(Basel)_10_Neuroprotective Effects of Black Pepper Cold-Pressed Oil on Scopolamine-Induced Oxidative Stress and Memory Impairment in Rats
Mota_2021_Neuroscientist__10738584211016409Alzheimer's Disease: Innovative Therapeutic Approaches Based on Peptides and Nanoparticles
Mottaghipisheh_2021_Pharmaceuticals.(Basel)_14_Linarin, a Glycosylated Flavonoid, with Potential Therapeutic Attributes: A Comprehensive Review
Motter_2021_Alzheimers.Dement.(Amst)_13_e12158Odor identification impairment and cholinesterase inhibitor treatment in Alzheimer's disease
Moujehed_2021_Colloids.Surf.B.Biointerfaces_211_112292Cleaner degreasing of sheepskins by the Yarrowia lipolytica LIP2 lipase as a chemical-free alternative in the leather industry
Mourad_2021_Basic.Clin.Neurosci_12_681A Neurochemical and Electrophysiological Study on the Combined Effects of Caffeine and Nicotine in the Cortex of Rats
Mourad_2021_Pharmaceuticals.(Basel)_14_Novel Potent and Selective DPP-4 Inhibitors: Design, Synthesis and Molecular Docking Study of Dihydropyrimidine Phthalimide Hybrids
Mourouzis_2021_Lipids.Health.Dis_20_12Lipoprotein-associated phospholipase A2 levels, endothelial dysfunction and arterial stiffness in patients with stable coronary artery disease
Moyano_2021_Food.Chem.Toxicol_152_112241Chlorpyrifos induces cell proliferation in MCF-7 and MDA-MB-231 cells, through cholinergic and Wnt/beta-catenin signaling disruption, AChE-R upregulation and oxidative stress generation after single and repeated treatment
Moyano_2021_Food.Chem.Toxicol__112614Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF/TrkA/P75(NTR) signaling disruption
Moyses_2021_3.Biotech_11_435Fungal and enzymatic bio-depolymerization of waste post-consumer poly(ethylene terephthalate) (PET) bottles using Penicillium species
Mphahlele_2021_Antioxidants.(Basel)_10_In Vitro Enzymatic and Kinetic Studies, and In Silico Drug-Receptor Interactions, and Drug-Like Profiling of the 5-Styrylbenzamide Derivatives as Potential Cholinesterase and beta-Secretase Inhibitors with Antioxidant Properties
Mu_2021_Neurol.Res.Int_2021_6009342Limb Muscle Reinnervation with the Nerve-Muscle-Endplate Grafting Technique: An Anatomical Feasibility Study
Mu_2021_Open.Life.Sci_16_703Prognostic value of the neutrophil-to-lymphocyte ratio in acute organophosphorus pesticide poisoning
Muellerleile_2021_Mol.Neurobiol__Neuroligin-3 Regulates Excitatory Synaptic Transmission and EPSP-Spike Coupling in the Dentate Gyrus In Vivo
Muema_2021_Pestic.Biochem.Physiol_178_104912Neurotoxic Zanthoxylum chalybeum root constituents invoke mosquito larval growth retardation through ecdysteroidogenic CYP450s transcriptional perturbations
Muhammed_2021_Toxicol.Res.(Camb)_10_983Toxicity and biochemical responses induced by phosmet in rainbow trout (Oncorhynchus mykiss)
Mukhametgalieva_2021_Biochim.Biophys.Acta.Proteins.Proteom__140733Steady-state kinetic analysis of human cholinesterases over wide concentration ranges of competing substrates
Mulcahy_2021_J.Neurochem__Protein profiling in the habenula after chronic (-)-menthol exposure in mice
Muley_2021_Bioprocess.Biosyst.Eng__Preparation of cross-linked enzyme aggregates of lipase from Aspergillus niger: process optimization, characterization, stability, and application for epoxidation of lemongrass oil
Mullard_2021_Nat.Rev.Drug.Discov_20_725What does AlphaFold mean for drug discovery?
Muller-Vahl_2021_Mov.Disord__Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A 12-Week, Randomized, Controlled Study
Muller-Vahl_2021_Pharmacopsychiatry__Endocannabinoid Modulation Using Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A Phase 1 Randomized, Placebo-Controlled Study
Muller_2021_Alzheimers.Dement.(N.Y)_7_e12153Structural MRI of the basal forebrain as predictor of cognitive response to galantamine in healthy older adults-A randomized controlled double-blinded crossover study
Muller_2021_Angew.Chem.Int.Ed.Engl_60_2013Discovery and Design of FamilyVIII Carboxylesterases as Highly Efficient Acyltransferases
Muller_2021_Biotechnol.Lett_43_287Synthesis of (R)-mandelic acid and (R)-mandelic acid amide by recombinant E. coli strains expressing a (R)-specific oxynitrilase and an arylacetonitrilase
Muller_2021_Diabetes.Metab.Res.Rev__e3504A Missense Variant Arg611Cys in LIPE which Encodes Hormone Sensitive Lipase Decreases Lipolysis and Increases Risk of Type 2 Diabetes in American Indians
Muller_2021_Microb.Cell.Fact_20_191Scaling production of GFP1-10 detector protein in E. coli for secretion screening by split GFP assay
Munch_2021_Eur.J.Pediatr__Digestive enzyme replacement relieves growth failure in preterm infants with poor exocrine pancreatic function: a retrospective case series
Munir_2021_Molecules_26_Microwave-Assisted Synthesis of (Piperidin-1-yl)quinolin-3-yl)methylene)hydrazinecarbothioamides as Potent Inhibitors of Cholinesterases: A Biochemical and In Silico Approach
Muniz-Gonzalez_2021_Environ.Sci.Pollut.Res.Int__Persistent pesticides: effects of endosulfan at the molecular level on the aquatic invertebrate Chironomus riparius
Muniz-Grijalvo_2021_Clin.Investig.Arterioscler_33 Suppl 2_56Familial chylomicronemia and multifactorial chylomicronemia
Muniz_2021_Environ.Pollut_283_117096Moxidectin toxicity to zebrafish embryos: Bioaccumulation and biomarker responses
Munoz_2021_Methods.Mol.Biol_2309_115Methods for Phenotyping Shoot Branching and Testing Strigolactone Bioactivity for Shoot Branching in Arabidopsis and Pea
Muramatsu_2021_J.Neurochem__Evaluation of radiolabeled acetylcholine synthesis and release in rat striatum
Murata_2021_Leg.Med.(Tokyo)_53_101929BIMP affects tubulin structure and causes abnormalities in cell division
Murray_2021_Life.Sci__119845Acute gene expression changes in the mouse hippocampus following a combined Gulf War toxicant exposure
Musaeus_2021_Curr.Alzheimer.Res__Pharmacological Medical Treatment of Epilepsy in Patients with Dementia: A Systematic Review
Mushtaq_2021_Plants.(Basel)_10_Biomolecular Evaluation of Lavandula stoechas L. for Nootropic Activity
Mustonen_2021_FEBS.J_288_3507Crystal and solution structure of NDRG1, a membrane-binding protein linked to myelination and tumour suppression
Mwagira-Maina_2021_Malar.J_20_461Genetic markers associated with insecticide resistance and resting behaviour in Anopheles gambiae mosquitoes in selected sites in Kenya
Myslivecek_2021_Front.Pharmacol_12_716460Social Isolation: How Can the Effects on the Cholinergic System Be Isolated?
Mzezewa_2021_J.Enzyme.Inhib.Med.Chem_36_1607Design, synthesis, and evaluation of 3,7-substituted coumarin derivatives as multifunctional Alzheimer's disease agents
Nadeem_2021_Antioxidants.(Basel)_11_Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
Nadeem_2021_Int.J.Biol.Macromol_193_19Fluoxetine and sertraline based multitarget inhibitors of cholinesterases and monoamine oxidase-A/B for the treatment of Alzheimer's disease: Synthesis, pharmacology and molecular modeling studies
Nagel_2021_BMC.Genomics_22_589Increased abundance of secreted hydrolytic enzymes and secondary metabolite gene clusters define the genomes of latent plant pathogens in the Botryosphaeriaceae
Najjar_2021_Sci.Rep_11_13659Optimizing the catalytic activities of methanol and thermotolerant Kocuria flava lipases for biodiesel production from cooking oil wastes
Nakagawa_2021_Surg.Today__Proximal subtotal pancreatectomy as an alternative to total pancreatectomy for malnourished patients
Nakamura_2021_ACS.Catal_11_8550Positive Charge Introduction on the Surface of Thermostabilized PET Hydrolase Facilitates PET Binding and Degradation
Nakamura_2021_Clin.Case.Rep_9_e04424Subcutaneous injection of organophosphate (Fenitrothion)-Management of preventing the appearance of toxic symptoms: A case report
Nakkam_2021_Br.J.Clin.Pharmacol__Genetic variants associated with severe cutaneous adverse reactions induced by carbamazepine
Nalbantoglu_2021_Ideggyogy.Sz_74_33Electrophysiological investigation for autonomic dysfunction in patients with myasthenia gravis: A prospective study
Naldi_2021_Molecules_26_Bio-Guided Fractionation of Stem Bark Extracts from Phyllanthus muellarianus: Identification of Phytocomponents with Anti-Cholinesterase Activity
Nambunmee_2021_J.Health.Pollut_11_210908Pesticide Spraying and Reduced Cholinesterase Activity among Hill Tribe Farmers in Thailand
Nan_2021_Drug.Des.Devel.Ther_15_2013Epigallocatechin-3-Gallate Provides Protection Against Alzheimer's Disease-Induced Learning and Memory Impairments in Rats
Nana_2021_J.Hazard.Mater_415_125752Colorimetric detection of chlorpyrifos in peach based on cobalt-graphene nanohybrid with excellent oxidase-like activity and reusability
Nandini_2021_J.Chem.Neuroanat__102069Combination of Ocimum sanctum extract and Levetiracetam ameliorates cognitive dysfunction and hippocampal architecture in rat model of Alzheimer's disease
Nar_2021_ChemMedChem_16_1425Action of Dipeptidyl Peptidase-4 Inhibitors on SARS-CoV-2 Main Protease
Nardello_2021_BMC.Med.Genomics_14_98A paradigmatic autistic phenotype associated with loss of PCDH11Y and NLGN4Y genes
Nascimento_2021_Biol.Trace.Elem.Res__Children Environmentally Exposed to Agrochemicals in Rural Areas Present Changes in Oxidative Status and DNA Damage
Nascimento_2021_Environ.Pollut_283_117054Polyethylene glycol acute and sub-lethal toxicity in neotropical Physalaemus cuvieri tadpoles (Anura, Leptodactylidae)
Naseem_2021_Exp.Brain.Res__Behavioural tagging: Effect of novelty exploration on plasticity related molecular signatures
Nasir_2021_J.Exp.Bot_72_1546Novel insights into host receptors and receptor-mediated signaling that regulate arbuscular mycorrhizal symbiosis
Nasso_2021_Pharmaceuticals.(Basel)_14_Annurca Apple Polyphenol Extract Affects Acetyl- Cholinesterase and Mono-Amine Oxidase In Vitro Enzyme Activity
Naughton_2021_Neurosci.Insights_16_26331055211020289The Carbamate, Physostigmine does not Impair Axonal Transport in Rat Cortical Neurons
Nawaz_2021_J.Med.Entomol__Current Status of Pyrethroids Resistance in Aedes aegypti (Culicidae: Diptera) in Lahore District, Pakistan: A Novel Mechanistic Insight
Nawaz_2021_J.Parkinsons.Dis__Anticholinergic Medication Burden in Parkinson's Disease Outpatients
Nazari_2021_EXCLI.J_20_907Novel 1,2,4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation
Nazario-Yepiz_2021_PLoS.One_16_e0255198Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase
Nazir_2021_BMC.Complement.Med.Ther_21_73Chemical composition, in vitro antioxidant, anticholinesterase, and antidiabetic potential of essential oil of Elaeagnus umbellata Thunb
Nazir_2021_Brain.Sci_11_Phytochemical Analysis, In Vitro Anticholinesterase, Antioxidant Activity and In Vivo Nootropic Effect of Ferula ammoniacum (Dorema ammoniacum) D. Don. in Scopolamine-Induced Memory Impairment in Mice
Ndongo_2021_Arch.Pharm.(Weinheim)__e2100150Microsequential injection analysis/lab-on-valve system for the automatic evaluation of acetylcholinesterase inhibitors
Neckermann_2021_Food.Res.Int_145_110395The efficacy and effect on gut microbiota of an aflatoxin binder and a fumonisin esterase using an in vitro simulator of the human intestinal microbial ecosystem (SHIME)
Nedogreeva_2021_Curr.Alzheimer.Res__Oxidative Damage of Proteins Precedes Loss of Cholinergic Phenotype in the Septal Neurons of Olfactory Bulbectomized Mice
Negi_2021_Curr.Drug.Metab__Medicinal Plants and Natural Products, More Effective and Safer Pharmacological Treatment for the Management of Obesity
Negrya_2021_Mol.Biol.(Mosk)_55_164[Glycol and Phosphate Depot Forms of 4- and/or 5-Modified Nucleosides Exhibiting Antibacterial Activity]
Nelson_2021_Plant.Physiol_185_1353The mechanism of host-induced germination in root parasitic plants
Nemade_2021_Aging.Dis_12_1021An Update on Medical and Surgical Treatments of Parkinson's Disease
Nemzer_2021_Molecules_26_Quantification of Major Bioactive Constituents, Antioxidant Activity, and Enzyme Inhibitory Effects of Whole Coffee Cherries (Coffea arabica) and Their Extracts
Nenaah_2021_Pest.Manag.Sci__The essential oil of Schinus terebinthifolius and its nanoemulsion and isolated monoterpenes: Investigation of their activity against Culex pipiens with insights into the adverse effects on non-target organisms
Nephale_2021_Environ.Sci.Pollut.Res.Int__Use of biomarkers in monitoring pollution status of urban rivers, Limpopo, South Africa
Neskovic_2021_Front.Pharmacol_12_656748Different Pharmacokinetics of Tramadol, O-Demethyltramadol and N-Demethyltramadol in Postoperative Surgical Patients From Those Observed in Medical Patients
Nett_2021_Proc.Natl.Acad.Sci.U.S.A_118_A metabolic regulon reveals early and late acting enzymes in neuroactive Lycopodium alkaloid biosynthesis
Neumann_2021_BMC.Neurol_21_422Cholinesterase inhibitor to prevent falls in Parkinson's disease (CHIEF-PD) trial: a phase 3 randomised, double-blind placebo-controlled trial of rivastigmine to prevent falls in Parkinson's disease
Nevskaya_2021_Molecules_26_Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential
Ng_2021_Int.J.Mol.Sci_22_A Novel Lipase from Lasiodiplodia theobromae Efficiently Hydrolyses C8-C10 Methyl Esters for the Preparation of Medium-Chain Triglycerides' Precursors
Ng_2021_Int.J.Mol.Sci_22_10339A Novel Lipase from Lasiodiplodia theobromae Efficiently Hydrolyses C8-C10 Methyl Esters for the Preparation of Medium-Chain Triglycerides' Precursors
Ng_2021_Molecules_26_Zymography for Picogram Detection of Lipase and Esterase Activities
Ngoupaye_2021_Int.J.Neurosci__1Alteration of the alpha5 GABA receptor and 5HTT lead to cognitive deficits associated with major depressive-like behaviors in a 14-day combined stress rat model
Nguyen_2021_Adv.Exp.Med.Biol_1286_183Therapeutic Strategies and Nano-Drug Delivery Applications in Management of Aging Alzheimer's Disease
Nguyen_2021_Colloids.Surf.B.Biointerfaces_200_111587An acetylcholinesterase-based biosensor for the detection of pesticides using liquid crystals confined in microcapillaries
Nguyen_2021_Int.J.Mol.Sci_22_Influence of Acetylcholine Esterase Inhibitors and Memantine, Clinically Approved for Alzheimer's Dementia Treatment, on Intestinal Properties of the Mouse
Nguyen_2021_J.Ethnopharmacol__114520The additive memory and healthspan enhancement effects by the combined treatment of mature silkworm powders and Korean angelica extracts
Nguyen_2021_Nat.Prod.Res__1A new flavonoid from the leaves of Garcinia mckeaniana Craib and alpha-glucosidase and acetylcholinesterase inhibitory activities
Nguyen_2021_Neurodegener.Dis.Manag_11_35Evaluation of rivastigmine in Alzheimer's disease
Ni_2021_Protein.J__QSSR Modeling of Bacillus Subtilis Lipase A Peptide Collision Cross-Sections in Ion Mobility Spectrometry: Local Descriptor Versus Global Descriptor
Nicewicz_2021_Environ.Sci.Pollut.Res.Int_28_9084Set of stress biomarkers as a practical tool in the assessment of multistress effect using honeybees from urban and rural areas as a model organism: a pilot study
Nichols_2021_Environ.Toxicol.Chem_40_148Addition of Phenylmethylsulfonyl Fluoride Increases the Working Lifetime of the Trout Liver S9 Substrate Depletion Assay, Resulting in Improved Detection of Low Intrinsic Clearance Rates
Nichols_2021_Toxicology__152719Reactivation of Organophosphate-inhibited Serum Butyrylcholinesterase by Novel Substituted Phenoxyalkyl Pyridinium Oximes and Traditional Oximes
Nicholson_2021_Curr.Res.Food.Sci_4_163Lipase-catalyzed glycerolysis extended to the conversion of a variety of edible oils into structural fats
Niemela_2021_PLoS.Comput.Biol_17_e1008426Positive allosteric modulators of lecithin: Cholesterol acyltransferase adjust the orientation of the membrane-binding domain and alter its spatial free energy profile
Nieto_2021_Ultrason.Sonochem_75_105606Ultrasound-assisted enzymatic synthesis of xylitol fatty acid esters in solvent-free conditions
Nilin_2021_Mar.Pollut.Bull_166_112233Biological responses of mangrove oysters (Crassostrea rhizophorae) and mercury contamination in an urban tropical estuary
Nilsson_2021_Am.J.Physiol.Endocrinol.Metab__Osteocyte- and late Osteoblast-derived NOTUM Reduces Cortical Bone Mass in Mice
Ning_2021_Biomacromolecules__Lipase-Catalyzed Synthesis and Characterization of Poly(glycerol sebacate)
Nishida_2021_Metabolomics_17_26Whole-body insulin resistance and energy expenditure indices, serum lipids, and skeletal muscle metabolome in a state of lipoprotein lipase overexpression
Niu_2021_Anal.Chem__Nitrogen-Doped Graphdiyne as a Robust Electrochemical Biosensing Platform for Ultrasensitive Detection of Environmental Pollutants
Niu_2021_Harmful.Algae_103_101996Toxic effects of the dinoflagellate Karenia mikimotoi on zebrafish (Danio rerio) larval behavior
Nkpaa_2021_Psychopharmacology.(Berl)__Selenium abates manganese-induced striatal and hippocampal toxicity via abrogation of neurobehavioral deficits, biometal accumulation, oxidative stress, inflammation, and caspase-3 activation in rats
Noazira_2021_Pak.J.Biol.Sci_24_13Effect of Cymbopogon citratus Essential Oil (EO) on Handling Stress in Giant Freshwater Prawn (Macrobrachium rosenbergii)
Noby_2021_Biorxiv_2_Structure guided engineering of a cold active esterase expands substrate range though a stabilisation mutation that allows access to a buried water chamber
Noby_2021_Biorxiv__Structure and dynamics of a cold-active esterase reveals water entropy and active site accessibility as the likely drivers for cold-adaptation
Noby_2021_Open.Biol_11_210182Structure and in silico simulations of a cold-active esterase reveals its prime cold-adaptation mechanism
Noguchi_2021_Cannabis.Cannabinoid.Res__Phenotypic Characterization of the Endocannabinoid-Degrading Enzyme Alpha/Beta-Hydrolase Domain 6 Knockout Rat
Nogueira_2021_Environ.Sci.Pollut.Res.Int_28_14681Cholinesterase characterization and effects of the environmental contaminants chlorpyrifos and carbofuran on two species of marine crabs, Carcinus maenas and Pachygrapsus marmoratus
Noh_2021_Basic.Clin.Pharmacol.Toxicol_128_605The clinical role of serum albumin in Organophospate poisoning
Noh_2021_Front.Oncol_11_634219A Diagnostic Method for Gastric Cancer Using Two-Photon Microscopy With Enzyme-Selective Fluorescent Probes: A Pilot Study
Noori_2021_Eur.J.Pharmacol__173974Role of Natural Products for the Treatment of Alzheimer's Disease
Noort_2021_Chem.Res.Toxicol__Verification of Exposure to Novichok Nerve Agents Utilizing a Semitargeted Human Butyrylcholinesterase Nonapeptide Assay
Noroozi_2021_J.Mol.Neurosci_71_761Identification of miRNA-mRNA Network in Autism Spectrum Disorder Using a Bioinformatics Method
Northington_2021_J.Comp.Neurol__Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia-ischemia
Novy_2021_J.Biol.Chem__101302Phylogenetic analysis and in-depth characterization of functionally and structurally diverse CE5 cutinases
Noyes_2021_Neuron__Memory suppressor genes: Modulating acquisition, consolidation, and forgetting
Nunes_2021_Bioprocess.Biosyst.Eng__Waste soybean frying oil for the production, extraction, and characterization of cell-wall-associated lipases from Yarrowia lipolytica
Nunes_2021_Foods_11_Influence of Gender and Age of Brown Seaweed (Fucus vesiculosus) on Biochemical Activities of Its Aqueous Extracts
Nurfazilah_2021_Steroids__108832Biocatalytic modifications of ethynodiol diacetate by fungi, anti-proliferative activity, and acetylcholineterase inhibitory of its transformed products
Nuthikattu_2021_Nutrients_13_Inhibition of Soluble Epoxide Hydrolase Is Protective against the Multiomic Effects of a High Glycemic Diet on Brain Microvascular Inflammation and Cognitive Dysfunction
Nutschel_2021_J.Chem.Inf.Model__Promiscuous Esterases Counterintuitively Are Less Flexible than Specific Ones
Nyquist_2021_Neurocrit.Care__Testing Soluble Epoxide Hydrolase Inhibition in Patients with Aneurysmal Subarachnoid Hemorrhage: Rare Diseases, Orphan Drugs, the Conundrum
O'Brien_2021_Cannabis.Cannabinoid.Res__Diacylglycerol Lipase-beta Knockout Mice Display a Sex-Dependent Attenuation of Traumatic Brain Injury-Induced Mortality with No Impact on Memory or Other Functional Consequences
Obafemi_2021_Metab.Brain.Dis__Combination of donepezil and gallic acid improves antioxidant status and cholinesterases activity in aluminum chloride-induced neurotoxicity in Wistar rats
Obara_2021_Yakugaku.Zasshi_141_245[Mechanism of the Long-lasting Potentiating Effect of Distigmine on Urinary Bladder Motility]
Obeng_2021_J.Med.Chem_64_6523Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery
Oboh_2021_J.Ayurveda.Integr.Med__Anticholinesterase activity and antioxidant properties of Heinsia crinita and Pterocarpus soyauxii in Drosophila melanogaster model
Oboh_2021_J.Food.Biochem__e13616Effect of citrus peels-supplemented diet on longevity, memory index, redox status, cholinergic and monoaminergic enzymes in Drosophila melanogaster model
Obringer_2021_Regul.Toxicol.Pharmacol__104918Effect of chain length and branching on the in vitro metabolism of a series of parabens in human liver S9, human skin S9, and human plasma
Obukhova_2021_Klin.Lab.Diagn_66_718Clinical significance of acetylcholinesterase activity in brain tumors
Oda_2021_Biophys.Physicobiol_18_168Structural basis for Ca(2+)-dependent catalysis of a cutinase-like enzyme and its engineering: application to enzymatic PET depolymerization
Oda_2021_Methods.Enzymol_648_159Cutinases from thermophilic bacteria (actinomycetes): From identification to functional and structural characterization
Oe_2021_Chem.Commun.(Camb)__An activator-induced quencher-detachment-based turn-on probe with a cationic substrate moiety for acetylcholinesterase
Ogidigo_2021_Pharm.Biol_59_444UPLC-PDA-ESI-QTOF-MS/MS fingerprint of purified flavonoid enriched fraction of Bryophyllum pinnatum; antioxidant properties, anticholinesterase activity and in silico studies
Ogidigo_2021_Toxicol.Mech.Methods__1Neuroprotective effect of Bryophyllum pinnatum flavonoids against aluminium chloride-induced neurotoxicity in rats
Ogungbemi_2021_Toxics_9_Assessing Combined Effects for Mixtures of Similar and Dissimilar Acting Neuroactive Substances on Zebrafish Embryo Movement
Ogunsuyi_2021_Nutr.Neurosci__1Dietary inclusions of Solanum vegetables mitigate aluminum-induced redox and inflammation-related neurotoxicity in Drosophila melanogaster model
Ogunyewo_2021_Biotechnol.Biofuels_14_171Accessory enzymes of hypercellulolytic Penicillium funiculosum facilitate complete saccharification of sugarcane bagasse
Oguro_2021_Int.J.Mol.Sci_22_DHA and Its Metabolites Have a Protective Role against Methylmercury-Induced Neurotoxicity in Mouse Primary Neuron and SH-SY5Y Cells
Oguro_2021_J.Gene.Med__e3402Global Brain Delivery of Neuroligin 2 Gene Ameliorates Seizures in A Mouse Model of Epilepsy
Oh_2021_J.Microbiol.Biotechnol__Chromenone Derivatives as Monoamine Oxidase Inhibitors from Marine-Derived MAR4 Clade Streptomyces sp. CNQ-031
Oh_2021_Sci.Rep_11_13953Acetylcholinesterase and monoamine oxidase-B inhibitory activities by ellagic acid derivatives isolated from Castanopsis cuspidata var. sieboldii
Ohta_2021_Environ.Microbiol__Degradation of ester linkages in rice straw components by Sphingobium species recovered from the sea bottom using a non-secretory tannase-family alpha/beta hydrolase
Ojo_2021_Molecules_26_Deciphering the Interactions of Bioactive Compounds in Selected Traditional Medicinal Plants against Alzheimer's Diseases via Pharmacophore Modeling, Auto-QSAR, and Molecular Docking Approaches
Okada_2021_Sci.Rep_11_13589Different cholinergic cell groups in the basal forebrain regulate social interaction and social recognition memory
Okazaki_2021_Planta_253_123Strigolactone signaling inhibition increases adventitious shoot formation on internodal segments of ipecac
Okazawa_2021_J.Pestic.Sci_46_242Germination stimulatory activity of bacterial butenolide hormones from Streptomyces albus J1074 on seeds of the root parasitic weed Orobanche minor
Okhuevbie_2021_Alzheimers.Dement_17 Suppl 12_e058353Evaluation of the effect of Donepezil hydrochloride on Ethanol-induced hippocampal damage
Okulus_2021_Foods_11_Enzymatic Production of Biologically Active 3-Methoxycinnamoylated Lysophosphatidylcholine via Regioselctive Lipase-Catalyzed Acidolysis
Oladapo_2021_J.Mol.Neurosci_71_431Naringin Confers Protection against Psychosocial Defeat Stress-Induced Neurobehavioral Deficits in Mice: Involvement of Glutamic Acid Decarboxylase Isoform-67, Oxido-Nitrergic Stress, and Neuroinflammatory Mechanisms
Olagoke_2021_Mol.Cell.Biochem_476_1109Streptozotocin induces brain glucose metabolic changes and alters glucose transporter expression in the Lobster cockroach; Nauphoeta cinerea (Blattodea: Blaberidae)
Olajide_2021_J.Mol.Neurosci__Hippocampal Degeneration and Behavioral Impairment During Alzheimer-Like Pathogenesis Involves Glutamate Excitotoxicity
Olayinka_2021_Metab.Brain.Dis__Quercetin mitigates scopolamine-induced memory dysfunction: impact on oxidative stress and cholinergic mechanisms
Oliart-Ros_2021_Molecules_26_Production and Characterization of Cross-Linked Aggregates of Geobacillus thermoleovorans CCR11 Thermoalkaliphilic Recombinant Lipase
Oliveira_2021_Ecotoxicol.Environ.Saf_210_111868Exposure to tricyclic antidepressant nortriptyline affects early-life stages of zebrafish (Danio rerio)
Oliveira_2021_Org.Biomol.Chem__Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors
Oliveira_2021_Pharmacol.Biochem.Behav_211_173300Scopolamine and MK-801 impair recognition memory in a new spontaneous object exploration task in monkeys
Oliveira_2021_Prep.Biochem.Biotechnol__1Production of new lipase from Preussia africana and partial characterization
Olivos_2021_Pediatr.Surg.Int__Current practice of rectal biopsies for the diagnosis of Hirschsprung's disease in Latin America: an international online survey
Olofinnade_2021_Cent.Nerv.Syst.Agents.Med.Chem__Concentration-dependent effects of dietary L-ascorbic acid fortification in the brain of healthy mice
Olofinnade_2021_Curr.Aging.Sci_14_154Hazelnut Modulates Neurobehaviour and Ameliorates Ageing-induced Oxidative Stress, and Caspase-3-Mediated Apoptosis in Mice
Olofinnade_2021_Endocr.Metab.Immune.Disord.Drug.Targets_21_1333Lepidium meyenii Supplemented Diet Modulates Neurobehavioral and Biochemical Parameters in Mice Fed High-Fat High-Sugar Diet
Olofinnade_2021_Front.Biosci.(Elite.Ed)_13_54Cucumeropsis mannii reverses high-fat diet induced metabolic derangement and oxidative stress
Olofinnade_2021_Front.Biosci.(Landmark.Ed)_26_537Corylus avellana L. modulates neurobehaviour and brain chemistry following high-fat diet
Olofinsan_2021_Andrologia__e14179Ocimum tenuiflorum mitigates iron-induced testicular toxicity via modulation of redox imbalance, cholinergic and purinergic dysfunctions, and glucose metabolizing enzymes activities
Omeiza_2021_Brain.Behav__e2227Melatonin salvages lead-induced neuro-cognitive shutdown, anxiety, and depressive-like symptoms via oxido-inflammatory and cholinergic mechanisms
Omi_2021_Cell.Biochem.Biophys__Current Knowledge on the Biology of Lysophosphatidylserine as an Emerging Bioactive Lipid
Omran_2021_Molecules_26_New Disulfiram Derivatives as MAGL-Selective Inhibitors
Omwenga_2021_Arch.Toxicol__Prediction of dose-dependent in vivo acetylcholinesterase inhibition by profenofos in rats and humans using physiologically based kinetic (PBK) modeling-facilitated reverse dosimetry
Onasanwo_2021_Metab.Brain.Dis__Moringa oleifera-supplemented diet protect against cortico-hippocampal neuronal degeneration in scopolamine-induced spatial memory deficit in mice: role of oxido-inflammatory and cholinergic neurotransmission pathway
Onder_2021_J.Proteome.Res__Rabbit Antidiethoxyphosphotyrosine Antibody, Made by Single B Cell Cloning, Detects Chlorpyrifos Oxon-Modified Proteins in Cultured Cells and Immunopurifies Modified Peptides for Mass Spectrometry
Ongnok_2021_Neurotherapeutics__Donepezil Protects Against Doxorubicin-Induced Chemobrain in Rats via Attenuation of Inflammation and Oxidative Stress Without Interfering With Doxorubicin Efficacy
Onguka_2021_Cell.Chem.Biol__Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host
Onikanni_2021_J.Inflamm.Res_14_6749Sterculia tragacantha Lindl Leaf Extract Ameliorates STZ-Induced Diabetes, Oxidative Stress, Inflammation and Neuronal Impairment
Ontko_2021_Sci.Rep_11_9677Cytochrome P450-epoxygenated fatty acids inhibit Muller glial inflammation
Orhan_2021_Curr.Neuropharmacol_19_2205Cholinesterase Inhibitory Potential of Quercetin towards Alzheimer's Disease - A Promising Natural Molecule or Fashion of the Day? - A Narrowed Review
Orondo_2021_Parasit.Vectors_14_335Insecticide resistance status of Anopheles arabiensis in irrigated and non-irrigated areas in western Kenya
Orr_2021_Front.Behav.Neurosci_15_668589Social Experience Regulates Endocannabinoids Modulation of Zebrafish Motor Behaviors
Orsolic_2021_Sci.Rep_11_11479Comprehensive machine learning based study of the chemical space of herbicides
Ortiz-Delgado_2021_Environ.Toxicol__Toxicity of malathion during Senegalese sole, Solea senegalensis larval development and metamorphosis: Histopathological disorders and effects on type B esterases and CYP1A enzymatic systems
Ortiz_2021_Arq.Neuropsiquiatr_79_283Language impairment in the moderate stage of dementia due to Alzheimer's disease
Ortmann_2021_ALTEX__Photomotor response data analysis approach to assess chemical neurotoxicity with the zebrafish embryo
Osawa_2021_Exp.Gerontol__111374Physical activity and all-cause mortality and mediators of the association in the very old
Oshige_2021_Bioorg.Med.Chem.Lett__128391Synthesis of 3-octadecanoxypropyl 6-deoxy-6-sulfo-alpha-D-glucopyranoside (ODSG) as a lipase-resistant SQAP derivative
Oshodi_2021_Mol.Biol.Rep__Molecular mechanisms involved in the prevention and reversal of ketamine-induced schizophrenia-like behavior by rutin: the role of glutamic acid decarboxylase isoform-67, cholinergic, Nox-2-oxidative stress pathways in mice
Osman_2021_RSC.Adv_11_25933Optimisation of a gold nanoparticle-based aptasensor integrated with image processing for the colorimetric detection of acephate using response surface methodology
Osman_2021_Toxicology__152904Effect of N-acetylcysteine on attenuation of chlropyrifos and its methyl analogue toxicity in male rats
Osmaniye_2021_Arch.Pharm.(Weinheim)__e2100450Design, synthesis, biological activity, molecular docking, and molecular dynamics of novel benzimidazole derivatives as potential AChE/MAO-B dual inhibitors
Ostojcic_2021_Biotechnol.Prog_37_e3109Production of biodiesel by Burkholderia cepacia lipase as a function of process parameters
Osuntokun_2021_Epilepsy.Behav_124_108333Proanthocyanidin from Vitis vinifera attenuates memory impairment due to convulsive status epilepticus
Otari_2021_Front.Pharmacol_12_817885Phytochemical Studies on Two Unexplored Endemic Medicinal Plants of India, Barleria terminalis and Calacanthus grandiflorus
Othman_2021_Nat.Prod.Res__1Bassiamide A, a new alkaloid from xero-halophyte Bassia indica Wight
Oviedo-Sarmiento_2021_Pestic.Biochem.Physiol_179_104941Fumigant toxicity and biochemical effects of selected essential oils toward the red flour beetle, Tribolium castaneum (Coleoptera: Tenebrionidae)
Owumi_2021_Environ.Toxicol.Pharmacol_89_103786Indole-3-propionic acid mitigates chlorpyrifos-mediated neurotoxicity by modulating cholinergic and redox-regulatory systems, inflammatory stress, apoptotic responses and DNA damage in rats
Oyebode_2021_Drug.Chem.Toxicol__1Methanol fraction of Ficus mucoso (welw) prevents iron-induced oxidative damage and alters mitochondrial dysfunction in Drosophila melanogaster
Oyeka_2021_Cureus_13_e15641Progressive Supranuclear Palsy: Improvement in Cognitive-Behavioral Disturbances and Motor-Function Disabilities Following Treatment With Antidepressants and Cholinesterase Inhibitors
Oyeniran_2021_J.Basic.Clin.Physiol.Pharmacol__Host-parasite relationship modulates the effect of African mistletoe leaves on the cholinergic, monoaminergic and carbohydrate hydrolyzing enzymes in fruit fly
Oyibo_2021_J.Basic.Clin.Physiol.Pharmacol__Carcinogen sodium arsenite disrupts antioxidant and redox homeostasis in Drosophila melanogaster
Oyovwi_2021_Biomed.Pharmacother_142_112022Kolaviron abates busulfan-induced episodic memory deficit and testicular dysfunction in rats: The implications for neuroendopathobiological changes during chemotherapy
Oyovwi_2021_Pestic.Biochem.Physiol_175_104833Repeated endosulfan exposure induces changes in neurochemicals, decreases ATPase transmembrane ionic-pumps, and increased oxidative/nitrosative stress in the brains of rats: Reversal by quercetin
Ozdemir_2021_Protein.J__Identification and Heterologous Production of a Lipase from Geobacillus kaustophilus DSM 7263(T) and Tailoring Its N-Terminal by a His-Tag Epitope
Ozkaya_2021_Acta.Chim.Slov_68_222Protective Effects of 3-benzoyl-7-hydroxy Coumarin on Liver of Adult Rat Exposed to Aluminium Chloride
Ozten_2021_Bioorg.Chem_115_105225Synthesis, molecular docking and molecular dynamics studies of novel tacrine-carbamate derivatives as potent cholinesterase inhibitors
P_2021_J.Biol.Chem__101466Cholinergic signalling at the body wall neuromuscular junction distally inhibits feeding behaviour in C. elegans
Pachon-Angona_2021_Future.Med.Chem__Synthesis of new Hantzsch adducts showing Ca(2+) channel blockade capacity, cholinesterase inhibition and antioxidant power
Paduraru_2021_Int.J.Mol.Sci_22_Vitamin C Mitigates Oxidative Stress and Behavioral Impairments Induced by Deltamethrin and Lead Toxicity in Zebrafish
Paiva_2021_Chem.Rev_121_9502Animal Fatty Acid Synthase: A Chemical Nanofactory
Pala_2021_Environ.Sci.Pollut.Res.Int_28_890Ameliorative effect of Fennel (Foeniculum vulgare) essential oil on chlorpyrifos toxicity in Cyprinus carpio
Palyzova_2021_Electrophoresis_42_1832Separation of regioisomers and enantiomers of triacylglycerols containing branched fatty acids (iso and/or anteiso)
Pan_2021_Chemosphere__132434Degradation and toxicity of the antidepressant fluoxetine in an aqueous system by UV irradiation
Pan_2021_Cureus_13_e13495CD26/Dipeptidyl Peptidase IV and Its Multiple Biological Functions
Pan_2021_Food.Funct__Ergothioneine exhibits longevity-extension effect in Drosophila melanogaster via regulation of cholinergic neurotransmission, tyrosine metabolism, and fatty acid oxidation
Pan_2021_Int.J.Environ.Res.Public.Health_18_Factors Affecting Rapid Cognitive Decline in Patients with Alzheimer's Disease: A Longitudinal Follow-Up Study
Pan_2021_Nature__NF1 mutation drives neuronal activity-dependent initiation of optic glioma
Panamito_2021_Molecules_26_Chemical Composition and Anticholinesterase Activity of the Essential Oil of Leaves and Flowers from the Ecuadorian Plant Lepechinia paniculata (Kunth) Epling
Pang_2021_Front.Pharmacol_12_737764Securidaca inappendiculata Polyphenol Rich Extract Counteracts Cognitive Deficits, Neuropathy, Neuroinflammation and Oxidative Stress in Diabetic Encephalopathic Rats via p38 MAPK/Nrf2/HO-1 Pathways
Pann_2021_J.Asian.Nat.Prod.Res__1Phenanthrenes from Dendrobium senile and their pancreatic lipase inhibitory activity
Papadopoulos_2021_Neurol.India_69_177The Relevance of Blepharoptosis in Diagnostic Suspicion of Myopathies
Papagiouvannis_2021_Med.Chem_17_1086Multi-Target Directed Compounds with Antioxidant and/or Anti- Inflammatory Properties as Potent Agents for Alzheimer's Disease
Papapostolou_2021_Pest.Manag.Sci_77_666Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece
Paprottka_2021_Cancers.(Basel)_13_Outcome and Safety after 103 Radioembolizations with Yttrium-90 Resin Microspheres in 73 Patients with Unresectable Intrahepatic Cholangiocarcinoma-An Evaluation of Predictors
Paradhipta_2021_Microorganisms_9_Effects of Inoculants Producing Antifungal and Carboxylesterase Activities on Corn Silage and Its Shelf Life against Mold Contamination at Feed-Out Phase
Paredes-Ruiz_2021_Neurotox.Res__On the Biomedical Properties of Endocannabinoid Degradation and Reuptake Inhibitors: Pre-clinical and Clinical Evidence
Park_2021_Appl.Biol.Chem_64_81Biochemical characterization of a family IV esterase with R-form enantioselectivity from a compost metagenomic library
Park_2021_Cureus_13_e19701Seropositive Muscle-Specific Tyrosine Kinase Myasthenia Gravis Presenting as a Late-Onset Isolated Sixth Nerve Palsy: A Case Report and a Brief Review of Subtypes of Myasthenia Gravis
Park_2021_Diabetes.Obes.Metab__Cardiovascular safety of evogliptin in patients with type 2 diabetes mellitus: a nationwide cohort study
Park_2021_Food.Chem_353_129459Erythorbyl fatty acid ester as a multi-functional food emulsifier: Enzymatic synthesis, chemical identification, and functional characterization of erythorbyl myristate
Park_2021_J.Microbiol.Biotechnol__Skin commensal fungus Malassezia and its lipases
Park_2021_Mar.Drugs_19_Ecklonia cava Attenuates PM(2.5)-Induced Cognitive Decline through Mitochondrial Activation and Anti-Inflammatory Effect
Park_2021_Microorganisms_9_Molecular Characterization of Novel Family IV and VIII Esterases from a Compost Metagenomic Library
Park_2021_PLoS.One_16_e0248395Association between dementia and systemic rheumatic disease: A nationwide population-based study
Park_2021_Pest.Manag.Sci__Insecticide resistance trait may contribute to genetic cluster change in Bemisia tabaci MED (Hemiptera: Aleyrodidae) as a potential driving force
Park_2021_Plants.(Basel)_10_Establishment of a Rapid Micropropagation System for Kaempferia parviflora Wall. Ex Baker: Phytochemical Analysis of Leaf Extracts and Evaluation of Biological Activities
Parrish_2021_Sci.Rep_11_3218Resolving whether inhalation of depleted uranium contributed to Gulf War Illness using high-sensitivity mass spectrometry
Parsons_2021_Am.Soc.Clin.Oncol.Educ.Book_41_e90Assessment and Management of Cognitive Symptoms in Patients With Brain Tumors
Parvez_2021_Drug.Metab.Dispos__Quantitative investigation of irinotecan metabolism, transport and gut microbiome activation
Parween_2021_PLoS.One_16_e0258879Association between human paraoxonase 2 protein and efficacy of acetylcholinesterase inhibiting drugs used against Alzheimer's disease
Pasandideh_2021_Int.J.Biol.Macromol__Evaluation of antioxidant and inhibitory properties of Citrus aurantium L. on the acetylcholinesterase activity and the production of amyloid nano-bio fibrils
Pashirova_2021_Chem.Biol.Interact__109577Therapeutic nanoreactors for detoxification of xenobiotics: Concepts, challenges and biotechnological trends with special emphasis to organophosphate bioscavenging
Patel_2021_Bioresour.Technol__125673Lipolytic Nocardiopsis for reduction of pollution load in textile industry effluent and SWISS model for structural study of lipase
Patel_2021_Inflammopharmacology__Protective effect of andrographolide against STZ induced Alzheimer's disease in experimental rats: possible neuromodulation and Abeta((1-42)) analysis
Patel_2021_J.Biomol.Struct.Dyn__1Carbazole-based semicarbazones and hydrazones as multifunctional anti-Alzheimer agents
Patel_2021_Saudi.J.Biol.Sci_28_3835Phyto-constituents profiling of Luffa echinata and in vitro assessment of antioxidant, anti-diabetic, anticancer and anti-acetylcholine esterase activities
Patil_2021_In.Silico.Pharmacol_9_51Erythrina variegata L. bark: an untapped bioactive source harbouring therapeutic properties for the treatment of Alzheimer's disease
Patil_2021_Indian.J.Pediatr__Lipoprotein Lipase Deficiency: Diet is the Key!
Patisaul_2021_Epilepsy.Behav_124_105001Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers
Patra_2021_Nanotechnology_32_235101Nanonization of a chemically synthesized flavone HMDF (3-hydroxy-3',4'-methylenedioxyflavone) by entrapping within calcium phosphate nanoparticles and exploring its antioxidant role on neural cells in vitro and zebrafish in vivo
Patra_2021_Nanotechnology__Nanonization of a chemically synthesized flavone HMDF (3-hydroxy-3',4'-methylenedioxyflavone) by entrapping within calcium phosphate nanoparticle (CPNP) and exploring its anti-oxidant role on neural cells in vitro and zebra fish in vivo
Pattanashetti_2021_Indian.J.Pharmacol_53_50Potential ameliorative effect of Cynodon dactylon (L.) pers on scopolamine-induced amnesia in rats: Restoration of cholinergic and antioxidant pathways
Patterson_2021_Immune.Netw_21_e35IL-17 and IL-17C Signaling Protects the Intestinal Epithelium against Diisopropyl Fluorophosphate Exposure in an Acute Model of Gulf War Veterans' Illnesses
Pavarina_2021_Sci.Rep_11_10440Characterization of a new bifunctional endo-1,4-beta-xylanase/esterase found in the rumen metagenome
Pavlidis_2021_J.Inorg.Biochem_217_111393Synthesis, characterization and pharmacological evaluation of quinoline derivatives and their complexes with copper() in in vitro cell models of Alzheimer's disease
Pavon_2021_Neurobiol.Stress_14_100293Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex
Pedrood_2021_Int.J.Biol.Macromol_170_1Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives
Pedroza-Gomez_2021_Pathogens_10_1454Transcriptome-Based Identification of a Functional Fasciola hepatica Carboxylesterase B
Pei_2021_Mikrochim.Acta_189_7Fluorine-free synthesis of Ti(3)C(2) MQDs for smartphone-based fluorescent and colorimetric determination of acetylcholinesterase and organophosphorus pesticides
Pekkoc_2021_Immunol.Invest__1Evaluation of IL1B rs1143634 and IL6 rs1800796 Polymorphisms with Autism Spectrum Disorder in the Turkish Children
Pelikan_2021_ISME.J_15_833Anaerobic bacterial degradation of protein and lipid macromolecules in subarctic marine sediment
Pellegrini_2021_J.Clin.Endocrinol.Metab__Generation of beta cells from iPSC of a MODY8 patient with a novel mutation in the carboxyl ester lipase (CEL) gene
Peluso_2021_Sci.Total.Environ_800_149510Comprehensive assessment of water quality through different approaches: Physicochemical and ecotoxicological parameters
Penatzer_2021_Heliyon_7_e07552Differential phosphoprotein signaling in the cortex in mouse models of Gulf War Illness using corticosterone and acetylcholinesterase inhibitors
Peng_2021_Brain.Sci_11_TPPU Pre-Treatment Rescues Dendritic Spine Loss and Alleviates Depressive Behaviours during the Latent Period in the Lithium Chloride-Pilocarpine-Induced Status Epilepticus Rat Model
Peng_2021_FEBS.Open.Bio_11_375A loss-of-function mutation p.T256M in NDRG4 is implicated in the pathogenesis of pulmonary atresia with ventricular septal defect (PA/VSD) and tetralogy of Fallot (TOF)
Peng_2021_J.Food.Biochem__e13667Stability comparison of four lipases and catalytic mechanism during the synthesis of 1,3-di-oleic-2-medium chain triacylglycerols in a trace water-in-oil system: Experimental analyses and computational simulations
Peng_2021_J.Mol.Graph.Model_110_108069Characterizing the potentially neuronal acetylcholinesterase reactivity toward chiral pyraclofos: Enantioselective insights from spectroscopy, in silico docking, molecular dynamics simulation and per-residue energy decomposition studies
Peng_2021_Phys.Chem.Chem.Phys__A distal regulatory strategy of enzymes: from local to global conformational dynamics
Peng_2021_Phytomedicine_93_153772Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota
Pengsook_2021_Pest.Manag.Sci__Insecticidal and growth inhibitory effects of some thymol derivatives on the beet armyworm, Spodoptera exigua (Lepidoptera: Noctuidae) and their impact on detoxification enzymes
Peran_2021_Psychopharmacology.(Berl)__Functional connectivity and cognitive changes after donepezil treatment in healthy participants
Perczyk_2021_Biochim.Biophys.Acta.Biomembr_1863_183620Simultaneous action of microbial phospholipase C and lipase on model bacterial membranes - Modeling the processes crucial for bioaugmentation
Pereira_2021_Chemosphere__132649Response of biomarkers to metals, hydrocarbons and organochlorine pesticides contamination in crabs (Callinectes ornatus and C. bocourti) from two tropical estuaries (Sao Jose and Sao Marcos bays) of the Maranho State (northeastern Brazil)
Pereira_2021_Molecules_26_Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights
Pereira_2021_Nat.Commun_12_459Degradation of complex arabinoxylans by human colonic Bacteroidetes
Perera_2021_Int.J.Geriatr.Psychiatry_36_271Factors associated with slow progression of cognitive impairment following first dementia diagnosis
Perez-Garcia_2021_Methods.Enzymol_648_137Exploring the global metagenome for plastic-degrading enzymes
Perez-Iglesias_2021_Arch.Environ.Contam.Toxicol__Multiple Level Effects of Imazethapyr on Leptodactylus latinasus (Anura) Adult Frogs
Perez-Sanchez_2021_J.Chem.Inf.Model_61_467Combined Structure and Ligand-Based Design of Selective Acetylcholinesterase Inhibitors
Perone_2021_ChemMedChem_16_187Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy
Perri_2021_Am.J.Hosp.Palliat.Care__1049909120985115Cholinesterase Inhibitor Use in Patients With Dementia Admitted to a Palliative Care Unit
Perrier_2021_Commun.Biol_4_665Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control
Perumal_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109021Mitigation of arsenic induced developmental cardiotoxicity by ferulic acid in zebrafish
Petkov_2021_Z.Naturforsch.C.J.Biosci__Receptor-mediated biological effects of extracts obtained from three Asplenium species
Petkova-Tuffy_2021_BMC.Biol_19_215Neuroligin-1 mediates presynaptic maturation through brain-derived neurotrophic factor signaling
Petrenko_2021_Biology.(Basel)_10_1021First Crystal Structure of Bacterial Oligopeptidase B in an Intermediate State: The Roles of the Hinge Region Modification and Spermine
Petric_2021_OMICS_25_38A Multi-Omics Analysis of PON1 Lactonase Activity in Relation to Human Health and Disease
Petrilla_2021_Toxins.(Basel)_13_A Comprehensive Study Monitoring the Venom Composition and the Effects of the Venom of the Rare Ethiopian Endemic Snake Species Bitis parviocula
Petrov_2021_Front.Mol.Neurosci_14_811220Cholinesterases in Tripartite Neuromuscular Synapse
Pezzilli_2021_Pancreas__Patients With Coronavirus Disease 2019 Interstitial Pneumonia Exhibit Pancreatic Hyperenzymemia and Not Acute Pancreatitis
Phachonpai_2021_Heliyon_7_e07003Cognition enhancing effects of Clausena lansium (Lour.) peel extract attenuate chronic restraint stress-induced memory deficit in rats
Phadke_2021_Chem.Biol.Drug.Des__Therapeutic potential of Ferulic acid and its derivatives in Alzheimer's disease- A systematic review
Pham_2021_Chem.Res.Toxicol__Using High-Throughput Screening to Evaluate Perturbations Potentially Linked to Neurobehavioral Outcomes: A Case Study Using Publicly Available Tools on FDA Batch-Certified Synthetic Food Dyes
Pham_2021_Micromachines.(Basel)_12_A Fluidics-Based Biosensor to Detect and Characterize Inhibition Patterns of Organophosphate to Acetylcholinesterase in Food Materials
Pham_2021_Microorganisms_9_Investigation of Lipolytic-Secreting Bacteria from an Artificially Polluted Soil Using a Modified Culture Method and Optimization of Their Lipase Production
Phaya_2021_Artif.Cells.Nanomed.Biotechnol_49_166Oxidative biotransformation of stemofoline alkaloids
Phillips_2021_Int.J.Hyg.Environ.Health_233_113691Acetylcholinesterase activity and thyroid hormone levels in Ecuadorian adolescents living in agricultural settings where organophosphate pesticides are used
Phillips_2021_J.Racial.Ethn.Health.Disparities_8_1153The Perfect Storm: COVID-19 Health Disparities in US Blacks
Piccialli_2021_Antioxidants.(Basel)_10_The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAbeta(1-42) Oligomers in Primary Cortical Neurons
Pierzynowski_2021_Biomed.Res.Int_2021_6647734Difference in Performance of EPI Pigs Fed Either Lipase-Predigested or Creon-Supplemented Semielemental Diet
Pineau_2021_Plant.Sci_307_110905CYP77B1 a fatty acid epoxygenase specific to flowering plants
Pineda-Martos_2021_Methods.Mol.Biol_2309_105Chemotropic Assay for Testing Fungal Response to Strigolactones and Strigolactone-Like Compounds
Piner_2021_Toxics_9_In Vivo Effects of Neonicotinoid-Sulfoximine Insecticide Sulfoxaflor on Acetylcholinesterase Activity in the Tissues of Zebrafish (Danio rerio)
Pinto_2021_ACS.Catal_11_10416Reaction Mechanism of MHETase, a PET Degrading Enzyme
Pinz_2021_Metab.Brain.Dis__Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na(+)/K(+)-ATPase in an Alzheimer's disease model
Pirillo_2021_FEBS.J_288_4730Analytical methods for the investigation of enzyme-catalyzed degradation of polyethylene terephthalate
Pirillo_2021_Int.J.Mol.Sci_23_An Efficient Protein Evolution Workflow for the Improvement of Bacterial PET Hydrolyzing Enzymes
Pirmanesh_2021_Iran.Biomed.J__Cloning, Expression, and Purification of a GDSL-like Lipase/Acylhydrolase from a Native Lipase-Producing Bacterium, Lactobacillus fermentum
Pirolla_2021_Curr.Drug.Targets_22_505Alzheimer's Disease: Related Targets, Synthesis of Available Drugs, Bioactive Compounds Under Development and Promising Results Obtained from Multi-target Approaches
Pisani_2021_Int.J.Geriatr.Psychiatry_36_1471A meta-analysis of randomised controlled trials of physical activity in people with Alzheimer's disease and mild cognitive impairment with a comparison to donepezil
Pleiss_2021_ChemCatChem_13_3909Standardized Data, Scalable Documentation, Sustainable Storage - EnzymeML As A Basis For FAIR Data Management In Biocatalysis
Ploug_2021_Curr.Opin.Lipidol__ANGPTL4: a new mode in the regulation of intravascular lipolysis
Poetini_2021_Dev.Biol_475_80Iron overload during the embryonic period develops hyperactive like behavior and dysregulation of biogenic amines in Drosophila melanogaster
Pohanka_2021_Mini.Rev.Med.Chem_21_660Pharmacological Influencing of The Cholinergic Anti-inflammatory Pathway in Infectious Diseases and Inflammatory Pathologies
Pohanka_2021_Sensors.(Basel)_21_A Smartphone Camera Colorimetric Assay of Acetylcholinesterase and Butyrylcholinesterase Activity
Poirier_2021_Environ.Sci.Pollut.Res.Int_28_25081Organophosphorus poisoning in animals and enzymatic antidotes
Polichnowski_2021_Am.J.Physiol.Regul.Integr.Comp.Physiol__Autonomic and cholinergic mechanisms mediating cardiovascular and temperature effects of donepezil in conscious mice
Poliseno_2021_Biomolecules_11_Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents
Poliserpi_2021_Chemosphere_284_131327Tissue distribution and sublethal effects of imidacloprid in the South American grayish baywing (Agelaioides badius)
Polopalli_2021_World.J.Biol.Psychiatry__1A prognostic study on the effect of post-traumatic stress disorder on cerebral ischaemia reperfusion-induced stroke
Pomara_2021_J.Affect.Disord_286_275Evidence of upregulation of the cholinergic anti-inflammatory pathway in late-life depression
Pont_2021_Eur.J.Med.Chem_225_113779From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects
Porfirio_2021_Int.J.Biol.Macromol_198_77Serine carboxypeptidases from the carnivorous plant Nepenthes mirabilis: Partial characterization and heterologous expression
Portela_2021_Naunyn.Schmiedebergs.Arch.Pharmacol_394_227Caffeic acid and caffeine attenuate toxicity associated with malonic or methylmalonic acid exposure in Drosophila melanogaster
Posadas-Sanchez_2021_Life.Sci_276_119410Dipeptidylpeptidase-4 levels and DPP4 gene polymorphisms in patients with COVID-19. Association with disease and with severity
Pospisil_2021_Methods.Mol.Biol_2309_31Synthesis of Simple Strigolactone Mimics
Potter_2021_Orphanet.J.Rare.Dis_16_235Enzyme replacement therapy and hematopoietic stem cell transplant: a new paradigm of treatment in Wolman disease
Pourabdi_2021_Front.Chem_9_810233Synthesis of New 3-Arylcoumarins Bearing N-Benzyl Triazole Moiety: Dual Lipoxygenase and Butyrylcholinesterase Inhibitors With Anti-Amyloid Aggregation and Neuroprotective Properties Against Alzheimer's Disease
Pouvreau_2021_Methods.Mol.Biol_2309_59Strigolactone-Like Bioactivity via Parasitic Plant Germination Bioassay
Prabu_2021_Fish.Physiol.Biochem__Antioxidant defence system based oxidative stress mitigation through dietary jamun tree leaf in experimentally infected snubnose pompano, Trachinotus blochii
Pradeep_2021_Front.Chem_9_741037Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-Based Calculations and Anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived From Acorus Calamus Plant Extract
Pradhan_2021_BMJ.Case.Rep_14_Hereditary pseudocholinesterase deficiency discovery after electroconvulsive therapy
Prado_2021_Neurocrit.Care__1Acetylcholinesterase Inhibitors in Myasthenic Crisis: A Systematic Review of Observational Studies
Praggastis_2021_Dev.Dyn_250_640The Drosophila E78 nuclear receptor regulates dietary triglyceride uptake and systemic lipid levels
Prakash_2021_Data.Brief_34_106721Dataset of Swimming behavioral alterations in Danio rerio by Nemopilema nomurai jellyfish venom
Prakashkumar_2021_Pharmaceutics_13_Decoding the Neuroprotective Potential of Methyl Gallate-Loaded Starch Nanoparticles against Beta Amyloid-Induced Oxidative Stress-Mediated Apoptosis: An In Vitro Study
Pralle_2021_Sci.Rep_11_2839Greater liver PNPLA3 protein abundance in vivo and in vitro supports lower triglyceride accumulation in dairy cows
Pramod_2021_Front.Plant.Sci_12_704960Saccharification Potential of Transgenic Greenhouse- and Field-Grown Aspen Engineered for Reduced Xylan Acetylation
Proenca_2021_An.Acad.Bras.Cienc_93_e20191002Purple grape juice consumption during the gestation reduces acetylcholinesterase activity and oxidative stress levels provoked by high-fat diet in hippocampus from adult female rats descendants
Prudente_2021_Environ.Toxicol.Chem_40_1132Nephrotoxic Effects Caused by Occupational Exposure to Agrochemicals in a Region of Northeastern Brazil: A Cross-Sectional Study
Pruthi_2021_Metab.Brain.Dis__Improvement of cognitive function in mice by Citrus reticulata var. kinnow via modulation of central cholinergic system and oxidative stress
Przybylowska_2021_Curr.Neuropharmacol_19_1323Therapeutic Potential of Multifunctional Derivatives of Cholinesterase Inhibitors
Przygrodzka_2021_Endocrinology__PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis
Pulido_2021_Biotechnol.Rep.(Amst)_31_e00659Ethanol as additive enhance the performance of immobilized lipase LipA from Pseudomonas aeruginosa on polypropylene support
Puljko_2021_Biochim.Biophys.Acta.Biomembr_1863_183475Redistribution of gangliosides accompanies thermally induced Na(+), K(+)-ATPase activity alternation and submembrane localisation in mouse brain
Pullaguri_2021_Toxicology__153080New insights into inhibitory nature of triclosan on acetylcholinesterase activity
Purgatorio_2021_ChemMedChem_16_589Evaluation of water-soluble Mannich base prodrugs of 2,3,4,5-tetrahydroazepino[4,3-b]indol-1(6H)-one as multitarget-directed agents for Alzheimer's disease
Purgatorio_2021_Molecules_26_First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease
Puspitasari_2021_Appl.Biochem.Biotechnol_193_1284Fungal Hydrophobin RolA Enhanced PETase Hydrolysis of Polyethylene Terephthalate
Puspitasari_2021_Int.J.Biol.Macromol_176_157Class I hydrophobins pretreatment stimulates PETase for monomers recycling of waste PETs
Puspitasari_2021_Int.J.Biol.Macromol_193_38Class I hydrophobin fusion with cellulose binding domain for its soluble expression and facile purification
Pyun_2021_Alzheimers.Res.Ther_13_10Change in cognitive function according to cholinesterase inhibitor use and amyloid PET positivity in patients with mild cognitive impairment
Qafary_2021_Int.J.Biol.Macromol_174_32Urea titration of a lipase from Pseudomonas sp. reveals four different conformational states, with a stable partially folded state explaining its high aggregation propensity
Qasim_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109112Host-pathogen interaction between Asian citrus psyllid and entomopathogenic fungus (Cordyceps fumosorosea) is regulated by modulations in gene expression, enzymatic activity and HLB-bacterial population of the host
Qi_2021_Cell.Rep_36_109469Nucleus basalis stimulation enhances working memory by stabilizing stimulus representations in primate prefrontal cortical activity
Qi_2021_Front.Microbiol_12_778828Evaluation of PET Degradation Using Artificial Microbial Consortia
Qi_2021_Nat.Prod.Res__1A glyoxylate-containing benzene derivative and butenolides from a marine algicolous fungus Aspergillus sp. SCSIO 41304
Qian_2021_Bioorg.Med.Chem_40_116187Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells
Qian_2021_Curr.Med.Chem__Research Progress on Dipeptidyl Peptidase Family: Structure, Function and Xenobiotic Metabolism
Qian_2021_Parasit.Vectors_14_169A survey of insecticide resistance-conferring mutations in multiple targets in Anopheles sinensis populations across Sichuan, China
Qiao_2021_Ecotoxicol.Environ.Saf_224_112672Chemical composition of essential oils from Thymus mongolicus, Cinnamomum verum, and Origanum vulgare and their acaricidal effects on Haemaphysalis longicornis (Acari: Ixodidae)
Qiao_2021_Phys.Chem.Chem.Phys__Effects of water on the solvation and structure of lipase in deep eutectic solvents containing a protein destabilizer and stabilizer
Qin_2021_J.Biotechnol_337_24A mutant T1 lipase homology modeling, and its molecular docking and molecular dynamics simulation with fatty acids
Qin_2021_J.Colloid.Interface.Sci_606_1229Hydrogen-bonded lipase-hydrogel microspheres for esterification application
Qin_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_269_120759An amplified fluorescence polarization assay for sensitive sensing of organophosphorus pesticides via MnO(2) nanosheets
Qiu_2021_Cell.Tissue.Res_383_1077Bile salt-dependent lipase promotes the barrier integrity of Caco-2 cells by activating Wnt/beta-catenin signaling via LRP6 receptor
Qiu_2021_Front.Cardiovasc.Med_8_639541Donepezil Ameliorates Pulmonary Arterial Hypertension by Inhibiting M2-Macrophage Activation
Qiu_2021_J.Basic.Microbiol__Microbial halophilic lipases: A review
Qiu_2021_J.Nutr_151_20Supplemental Choline Modulates Growth Performance and Gut Inflammation by Altering the Gut Microbiota and Lipid Metabolism in Weaned Piglets
Qu_2021_Clin.Lab_67_Evaluation of Lipoprotein-Associated Phospholipase A2 as a Prognostic Biomarker in Chronic Kidney Disease
Qu_2021_J.Cell.Physiol_236_4738Androgen-dependent miR-125a-5p targets LYPLA1 and regulates global protein palmitoylation level in late-onset hypogonadism males
Qu_2021_J.Med.Entomol__Multiple Genetic Mutations Related to Insecticide Resistance are Detected in Field Kazakhstani House Flies (Muscidae: Diptera)
Qu_2021_Talanta_224_121831Determination of butyrylcholinesterase activity based on thiamine luminescence modulated by MnO(2) nanosheets
Quan_2021_Int.J.Biol.Sci_17_3288The role of N-cadherin/c-Jun/NDRG1 axis in the progression of prostate cancer
Quan_2021_J.Nat.Prod__Configurational Assignment of a Flexible Benzo[g]isochromene Stereodiad from Rubia philippinensis and Inhibition of Soluble Epoxide Hydrolase Activity
Queda_2021_Molecules_26_Novel Donepezil-Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer's Disease
Quesada_2021_Environ.Toxicol.Chem__Early Toxic Effects in a Central American Native Fish (Parachromis dovii) Exposed to Chlorpyrifos and Difenoconazole
Quezada_2021_Molecules_26_Curcumin-Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders
Quimque_2021_ACS.Omega_6_8403Potential Cancer- and Alzheimer's Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening
Quinn_2021_Eur.J.Neurol__European Stroke Organisation (ESO) and European Academy Neurology (EAN) Joint Guidelines on Post Stroke Cognitive Impairment
Quinn_2021_Eur.Stroke.J_6_IEuropean Stroke Organisation and European Academy of Neurology joint guidelines on post-stroke cognitive impairment
Quratulain_2021_Pak.J.Pharm.Sci_34_1989Synthesis, characterization, SAR, antioxidant, anti-acetylcholinesterase and anti-butyrylcholinesterase activities of cephradine Schiff bases
Qurrat_2021_Biomed.Pharmacother_146_112561Multi-activity tetracoordinated pallado-oxadiazole thiones as anti-inflammatory, anti-Alzheimer, and anti-microbial agents: Structure, stability and bioactivity comparison with pallado-hydrazides
Radhakrishnan_2021_Chemosphere_287_132163Target-receptive structural switching of ssDNA as selective and sensitive biosensor for subsequent detection of toxic Pb(2+) and organophosphorus pesticide
Radic_2021_Crystals_11_1557Shifts in backbone conformation of acetylcholinesterases upon binding of covalent inhibitors, reversible ligands and substrates
Rafat_2021_Biosensors.(Basel)_11_Electrochemical Biosensor for Markers of Neurological Esterase Inhibition
Rafeeq_2021_Biotechnol.Appl.Biochem__Esterases as emerging biocatalysts-mechanistic insights, genomic and metagenomic, immobilization and biotechnological applications
Rafiqah_2021_Polymers.(Basel)_13_A Review on Properties and Application of Bio-Based Poly(Butylene Succinate)
Raghuvanshi_2021_Phytomedicine_91_153659Identification of plant-based multitargeted leads for Alzheimer's disease: In-vitro and in-vivo validation of Woodfordia fruticosa (L.) Kurz
Rahman_2021_J.Physiol.Pharmacol_72_Neuropharmacological investigation, ultra-high performance liquid chromatography analysis, and in silico studies of Phyla nodiflora
Rahman_2021_Molecules_26_Thiourea Derivatives, Simple in Structure but Efficient Enzyme Inhibitors and Mercury Sensors
Rahman_2021_Molecules_27_Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects
Rahman_2021_PLoS.One_16_e0258201Case Study Using Recommended Reference Genes Actin and 18S for Reverse-Transcription Quantitative Real-Time PCR Analysis in Myzus persicae
Rahmania_2021_Pharm.Sci.Res_8_73Chemical Properties, Biological Activities and Poisoning Treatment of Novichok: A Review
Rai_2021_Biomed.Pharmacother_137_111377Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases
Raji_2021_FEBS.Lett_595_351The coordinated action of glucuronoyl esterase and alpha-glucuronidase promotes the disassembly of lignin-carbohydrate complexes
Rakhmat,_2021_Diabetes.Metab.Syndr_15_777Dipeptidyl peptidase-4 (DPP-4) inhibitor and mortality in coronavirus disease 2019 (COVID-19) - A systematic review, meta-analysis, and meta-regression
Ramachandran_2021_Biotechnol.Lett_43_279FSH1 encodes lysophospholipase activity in Saccharomyces cerevisiae
Ramachandran_2021_Curr.Neuropharmacol_19_679Neurodegenerative Pathways in Alzheimer's Disease: A Review
Ramalakshmi_2021_Mini.Rev.Med.Chem__Multitarget Directed Ligand Approaches for Alzheimer's Disease: A Complete Review
Ramasamy_2021_Environ.Sci.Pollut.Res.Int__Chemical characterization of billy goat weed extracts Ageratum conyzoides (Asteraceae) and their mosquitocidal activity against three blood-sucking pests and their non-toxicity against aquatic predators
Rambabu_2021_Clin.Toxicol.(Phila)__1Acute phenthoate self-poisoning: a prospective case series
Ramesh_2021_Curr.Biol__Antagonistic interactions between two Neuroligins coordinate pre- and postsynaptic assembly
Ramirez_2021_Br.J.Clin.Pharmacol__Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib
Ramirez_2021_Structure_29_635Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions?
Ramos-Flores_2021_Toxicol.Sci__Temephos decreases sperm quality and fertilization rate and is metabolized in rat reproductive tissues at low dose exposure
Ran_2021_Ecotoxicol.Environ.Saf_226_112809The enantioselective toxicity and oxidative stress of dinotefuran on zebrafish (Danio rerio)
Rangel_2021_PLoS.One_16_e0251556Multicomponent carbohydrase system from Trichoderma reesei: A toolbox to address complexity of cell walls of plant substrates in animal feed
Rani_2021_Biomolecules_11_Short- and Long-Term Social Recognition Memory Are Differentially Modulated by Neuronal Histamine
Rani_2021_Bioorg.Chem_114_1050531H-1,2,3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice brain cells
Rani_2021_J.Basic.Clin.Physiol.Pharmacol__Pharmacological investigations on efficacy of Phlorizin a sodium-glucose co-transporter (SGLT) inhibitor in mouse model of intracerebroventricular streptozotocin induced dementia of AD type
Rani_2021_J.Genet.Eng.Biotechnol_19_73Study of lipase producing gene in wheat - an in silico approach
Rankovic_2021_Heart.Fail.Rev_26_437Dipeptidyl peptidase-4 inhibitors as new tools for cardioprotection
Ranneh_2021_Saudi.J.Biol.Sci_28_6711Anti-aging and antioxidant of four traditional malaysian plants using simplex centroid mixture design approach
Rants'o_2021_J.Mol.Graph.Model_110_108054Optimization of covalent docking for organophosphates interaction with Anopheles acetylcholinesterase
Rao_2021_Appl.Biochem.Biotechnol_193_560Immobilized Arabidopsis thaliana Hydroxynitrile Lyase-Catalyzed Retro-Henry Reaction in the Synthesis of (S)-beta-Nitroalcohols
Rao_2021_Sci.Rep_11_17474Revealing the molecular interplay of curcumin as Culex pipiens Acetylcholine esterase 1 (AChE1) inhibitor
Rapichai_2021_Biotechnol.Lett__MPH-GST sensing microplate for easy detection of organophosphate insecticides
Rasch_2021_Pancreatology_21_306High lipasemia is frequent in Covid-19 associated acute respiratory distress syndrome
Rashedinia_2021_Biomed.Res.Int_2021_5577594The Effect of a Traditional Preparation Containing Piper nigrum L. and Bunium persicum (Boiss.) B.Fedtsch. on Immobility Stress-Induced Memory Loss in Mice
Rastegari_2021_Mol.Divers__Synthesis and evaluation of novel arylisoxazoles linked to tacrine moiety: in vitro and in vivo biological activities against Alzheimer's disease
Rawlings_2021_Biochem.(Lond)_43_73Alan Barrett: an appreciation (21 August 1937-23 November 2020)
Rawlings_2021_Protein.Sci_30_83How to use the MEROPS database and website to help understand peptidase specificity
Rawsthorne_2021_Hum.Mol.Genet_29_3546Neuroligin dependence of social behaviour in Caenorhabditis elegans provides a model to investigate an autism-associated gene
Raymond_2021_J.Pers.Med_11_Pharmacogenetics of Direct Oral Anticoagulants: A Systematic Review
Raza_2021_J.Thorac.Dis_13_6187Robotic thymectomy for myasthenia gravis surgical techniques and outcomes
Reale_2021_J.Alzheimers.Dis__Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia with Lewy Bodies from Alzheimer's Disease
Recart_2021_Int.J.Dev.Neurosci__Gallic acid protects cerebral cortex, hippocampus, and striatum against oxidative damage and cholinergic dysfunction in an experimental model of manic-like behavior: comparison with lithium effects
Reddy_2021_Environ.Res__111320In-vitro evaluation of antioxidant and anticholinesterase activities of novel pyridine, quinoxaline and s-triazine derivatives
Redondo-Lopez_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_251_109208Transient exposure to sublethal concentrations of a pesticide mixture (chlorpyrifos-difenoconazole) caused different responses in fish species from different trophic levels of the same community
Refaey_2021_Bioorg.Chem_108_104643Bioactive constituents from Thunbergia erecta as potential anticholinesterase and anti-ageing agents: Experimental and in silico studies
Rege_2021_Drugs.Aging__Antipsychotic Initiation Among Older Dementia Patients Using Cholinesterase Inhibitors: A National Retrospective Cohort Study
Rehman_2021_Saudi.J.Biol.Sci_28_592Biochemical Profiling and Elucidation of Biological Activities of Beta vulgaris L. Leaves and Roots Extracts
Rehuman_2021_ACS.Omega_6_28182Halogenated Coumarin-Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors
Reid_2021_Curr.Alzheimer.Res__Interaction of Exogenous Butyrylcholinesterase with beta-Amyloid Plaques in 5XFAD/Butyrylcholinesterase-Knockout Mouse Brain
Reid_2021_J.Comp.Neurol_529_1029Distribution of acetylcholinesterase in the hippocampal formation of the Atlantic white-sided dolphin (Lagenorhynchus acutus)
Reijngoud_2021_Biotechnol.Lett__Loss of function of the carbon catabolite repressor CreA leads to low but inducer-independent expression from the feruloyl esterase B promoter in Aspergillus niger
Reisbeck_2021_Polymers.(Basel)_13_Gram Scale Synthesis of Dual-Responsive Dendritic Polyglycerol Sulfate as Drug Delivery System
Rejc_2021_Theranostics_11_6542Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease
Remsberg_2021_Nat.Chem.Biol__ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth
Remya_2021_Comput.Struct.Biotechnol.J_19_4517Neuroprotective derivatives of tacrine that target NMDA receptor and acetyl cholinesterase - Design, synthesis and biological evaluation
Remya_2021_Int.J.Biol.Macromol__Chemical similarity assisted search for acetylcholinesterase inhibitors: Molecular modeling and evaluation of their neuroprotective properties
Ren_2021_Analyst_145_8022Light-accelerating oxidase-mimicking activity of black phosphorus quantum dots for colorimetric detection of acetylcholinesterase activity and inhibitor screening
Ren_2021_Biol.Trace.Elem.Res__Effect of Selenium on Brain Injury in Chickens with Subacute Arsenic Poisoning
Ren_2021_Eur.J.Med.Chem_228_114031Imidazolylacetophenone oxime-based multifunctional neuroprotective agents: Discovery and structure-activity relationships
Ren_2021_J.Basic.Microbiol_61_55Biodegradation of erythromycin by Delftia lacustris RJJ-61 and characterization of its erythromycin esterase
Rennison_2021_Polymers.(Basel)_13_Rational Protein Engineering to Increase the Activity and Stability of IsPETase Using the PROSS Algorithm
Repp_2021_Nanomaterials.(Basel)_11_Oligo(Lactic Acid)(8)-Docetaxel Prodrug-Loaded PEG-b-PLA Micelles for Prostate Cancer
Reyhani_2021_J.Econ.Entomol__Salicylic Acid Induced Resistance in Drought-Stressed Pistachio Seedlings Influences Physiological Performance of Agonoscena pistaciae (Hemiptera: Aphalaridae)
Reyna_2021_Ecotoxicol.Environ.Saf_208_111603What does the freshwater clam, Corbicula largillierti, have to tell us about chlorothalonil effects?
Rezaee_2021_Mol.Divers_25_45Novel amide derivatives of 3-phenylglutaric acid as potent soluble epoxide hydrolase inhibitors
Rhee_2021_Diabetes.Metab.J__Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19
Riaz_2021_Bioorg.Chem_114_105069Synthesis, biological activity and docking calculations of bis-naphthoquinone derivatives from Lawsone
Ribeiro_2021_Acta.Trop__106089Molluscicidal activity of monoterpenes and their effects on inhibition of acetylcholinesterase activity on Biomphalaria glabrata, an intermediate host of Schistosoma mansoni
Ribitsch_2021_Methods.Enzymol_648_293Tuning of adsorption of enzymes to polymer
Richbart_2021_Adv.Cancer.Res_152_1Acetylcholinesterase and human cancers
Richert_2021_Int.J.Biol.Macromol_176_226Enzymatic degradation and biofilm formation during biodegradation of polylactide and polycaprolactone polymers in various environments
Richter_2021_Metabolites_11_In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists QMPSB and QMPCB (SGT-11) Including Isozyme Mapping and Esterase Activity
Rios_2021_Environ.Sci.Pollut.Res.Int__Impact of dietary lipid level on esterase enzyme activities in the non-target freshwater shrimp Macrobrachium borellii exposed to chlorpyrifos
Rishitha_2021_Alzheimers.Dement_17 Suppl 12_e058344Therapeutic investigation of alpha napthoflavone in the intracerebroventricular injection of L-cysteine induced vascular dementia in rats
Riswanto_2021_Med.Chem_17_442Anti-Cholinesterase Activity of Chalcone Derivatives: Synthesis, In Vitro Assay and Molecular Docking Study
Robert_2021_Cells_10_The Endothelium Is Both a Target and a Barrier of HDL's Protective Functions
Roberts_2021_Sci.Immunol_6_Acetylcholine production by group 2 innate lymphoid cells promotes mucosal immunity to helminths
Robichaud_2021_Autophagy__Identification of Novel Lipid Droplet Factors that Regulate Lipophagy and Cholesterol Efflux in Macrophage Foam Cells
Robson_2021_Nat.Rev.Cardiol__Blocking endothelial lipase raises HDL-C levels
Rocchetti_2021_Food.Chem_368_130782The functional potential of nine Allium species related to their untargeted phytochemical characterization, antioxidant capacity and enzyme inhibitory ability
Roda_2021_ACS.Catal_11_3590Computationally Driven Rational Design of Substrate Promiscuity on Serine Ester Hydrolases
Rodrigues_2021_Psychopharmacology.(Berl)__The neurotherapeutic role of a selenium-functionalized quinoline in hypothalamic obese rats
Rodriguez-Enriquez_2021_ChemMedChem_16_1797-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation
Rodriguez-Salarichs_2021_J.Chem.Inf.Model__Versatile Lipases from the Candida rugosa-like Family: A Mechanistic Insight Using Computational Approaches
Rodriguez-Solana_2021_J.Sci.Food.Agric_101_4076Influence of elaboration process on chemical, biological, and sensory characteristics of European pennyroyal liqueurs
Rodriguez_2021_Neuromuscul.Disord_31_21Presynaptic congenital myasthenic syndrome due to three novel mutations in SLC5A7 encoding the sodium-dependant high-affinity choline transporter
Rodriguez_2021_Sci.Total.Environ_794_148754Efficient production of polyhydroxybutyrate from slaughterhouse waste using a recombinant strain of Cupriavidus necator DSM 545
Roesler_2021_Front.Plant.Sci_12_639401Arabidopsis Carboxylesterase 20 Binds Strigolactone and Increases Branches and Tillers When Ectopically Expressed in Arabidopsis and Maize
Rolim_2021_Pest.Manag.Sci__Field-evolved resistance to beta-cyfluthrin in the boll weevil - detection and characterization
Rolly_2021_Genes.(Basel)_12_Insights into the Transcriptional Regulation of Branching Hormonal Signaling Pathways Genes under Drought Stress in Arabidopsis
Rompicherla_2021_Naunyn.Schmiedebergs.Arch.Pharmacol__Pharmacokinetic and pharmacodynamic evaluation of nasal liposome and nanoparticle based rivastigmine formulations in acute and chronic models of Alzheimer's disease
Rompikuntal_2021_mSphere_6_Blocking Palmitoylation of Toxoplasma gondii Myosin Light Chain 1 Disrupts Glideosome Composition but Has Little Impact on Parasite Motility
Rong_2021_Curr.Pharm.Des_27_332Enhancing Therapeutic Efficacy of Donepezil by Combined Therapy: A Comprehensive Review
Rong_2021_J.Med.Chem__Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold
Roohigohar_2021_PeerJ_9_e11762Gene selection for studying frugivore-plant interactions: a review and an example using Queensland fruit fly in tomato
Rosier_2021_iScience_24_103460Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function
Ross_2021_J.Appl.Crystallogr_54_895Aerosol-based ligand soaking of reservoir-free protein crystals
Rossi_2021_J.Med.Chem__Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease
Rostami-Mansoor_2021_Int.J.Mol.Cell.Med_10_149Modulation of mRNA Expression of Monoacylglycerol Lipase, Diacylglycerol Lipase and Cannabinoid Receptor-1 in Mice Experimentally Infected with T. gondii
Roumeliotis_2021_Oxid.Med.Cell.Longev_2021_8817502Association of rs11780592 Polymorphism in the Human Soluble Epoxide Hydrolase Gene (EPHX2) with Oxidized LDL and Mortality in Patients with Diabetic Chronic Kidney Disease
Roussel_2021_Diabetes.Obes.Metab__Use of Dipeptidyl Peptidase-4 inhibitors and prognosis of COVID-19 in hospitalized patients with type 2 diabetes: a propensity score analysis from the CORONADO study
Rozi_2021_Mol.Phylogenet.Evol__107381Ancestral Sequence Reconstruction of Ancient Lipase from Family I.3 Bacterial Lipolytic Enzymes
Ruangritchankul_2021_Ther.Clin.Risk.Manag_17_927Adverse Drug Reactions of Acetylcholinesterase Inhibitors in Older People Living with Dementia: A Comprehensive Literature Review
Rubio-Vargas_2021_Environ.Toxicol.Pharmacol_87_103682Exposure to pollutants present in Iguacu River Southern Brazil affect the health of Oreochromis niloticus (Linnaeus, 1758): Assessment histological, genotoxic and biochemical
Rudolph_2021_ACS.Omega_6_13466Aryl N-[-(6-Fluoroindol-1-yl)alkyl]carbamates as Inhibitors of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and Butyrylcholinesterase: Structure-Activity Relationships and Hydrolytic Stability
Ruff_2021_Arterioscler.Thromb.Vasc.Biol__ATVBAHA120315757LEGACY: Phase 2a Trial to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of the Anti-EL (Endothelial Lipase) Antibody MEDI5884 in Patients With Stable Coronary Artery Disease
Ruff_2021_J.Mol.Biol_433_167208AlphaFold and Implications for Intrinsically Disordered Proteins
Rutkoski_2021_Environ.Sci.Pollut.Res.Int_28_4377Cypermethrin- and fipronil-based insecticides cause biochemical changes in Physalaemus gracilis tadpoles
Ruvinda_2021_Bull.Environ.Contam.Toxicol__Toxicity of Titanium Dioxide Nanoparticles to Tadpoles of Asian Common Toad (Duttaphrynus melanostictus) Following Short Term and Chronic Exposures
Ruzov_2021_Vopr.Kurortol.Fizioter.Lech.Fiz.Kult_98_32[Serum concentration of phospholipase A2 and platelet aggregation during hyperbaric oxygen therapy in patients with ischemic heart disease]
Saad_2021_ACG.Case.Rep.J_8_e00516The Emerging Battle: Lysosomal Acid Lipase Deficiency vs Familial Hypercholesterolemia in Children
Saber_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1177_122759Chemometric-enhanced metabolic profiling of five Pinus species using HPLC-MS/MS spectrometry: Correlation to in vitro anti-aging, anti-Alzheimer and antidiabetic activities
Saber_2021_J.Enzyme.Inhib.Med.Chem_36_618Phytochemical profile, enzyme inhibition activity and molecular docking analysis of Feijoa sellowiana O. Berg
Sabnis_2021_ACS.Med.Chem.Lett_12_312Novel Oxazine Monoacylglycerol Lipase (MAGL) Inhibitors
Sadafi_2021_Mol.Divers__Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheimer's disease: Quinolotacrine hybrids
Saegusa_2021_Ann.Nutr.Metab__Serum cholinesterase levels to predict all-cause mortality in a community-based study: The Takahata study
Safa_2021_J.Nat.Prod__Spatial Distribution and Stability of Cholinesterase Inhibitory Protoberberine Alkaloids from Papaver setiferum
Safdari_2021_Adv.Exp.Med.Biol_1328_287Role of Herbal Medicines in the Management of Brain Injury
Sagbohan_2021_Parasit.Vectors_14_202Intensity and mechanisms of deltamethrin and permethrin resistance in Anopheles gambiae s.l. populations in southern Benin
Sager_2021_An.Acad.Bras.Cienc_93_e20201938Multibiomarker responses in Danio rerio after exposure to sediment spiked with triclosan
Sager_2021_J.Toxicol.Environ.Health.A__1Oxidative stress responses after exposure to triclosan sublethal concentrations: an integrated biomarker approach with a native (Corydoras paleatus) and a model fish species (Danio rerio)
Sagong_2021_J.Hazard.Mater__Implications for the PET decomposition mechanism through similarity and dissimilarity between PETases from Rhizobacter gummiphilus and Ideonella sakaiensis
Saha_2021_Thorac.Cardiovasc.Surg_69_693Diagnostic Value of Cholinesterase Activity for the Development of Postoperative Delirium after Cardiac Surgery
Saha_2021_Thorac.Cardiovasc.Surg__Diagnostic Value of Cholinesterase Activity for the Development of Postoperative Delirium after Cardiac Surgery
Sahaka_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1173_122674Quantitative monitoring of galactolipid hydrolysis by pancreatic lipase-related protein 2 using thin layer chromatography and thymol-sulfuric acid derivatization
Sahin_2021_J.Biomol.Struct.Dyn__1Synthesis, characterization, molecular docking and in vitro screening of new metal complexes with coumarin Schiff base as anticholine esterase and antipancreatic cholesterol esterase agents
Sahoo_2021_J.Biomol.Struct.Dyn__1Comprehensive sequence and structure analysis of algal lipid catabolic enzyme Triacylglycerol lipase: an in silico study to vitalize the development of optimum engineered strains with high lipid productivity
Saidani_2021_Mar.Pollut.Bull_169_112556Toxicity assessment of organophosphorus in Ruditapes decussatus via physiological, chemical and biochemical determination: A case study with the compounds gamma-oximo- and gamma-amino-phosphonates and phosphine oxides
Sajjad_2021_Saudi.J.Biol.Sci_28_4384Chemical characterization and evaluation of the neuroprotective potential of Indigofera sessiliflora through in-silico studies and behavioral tests in scopolamine-induced memory compromised rats
Sajjadi_2021_Metab.Brain.Dis__Amygdalus spinosissima root extract enhanced scopolamine-induced learning and memory impairment in mice
Sakai_2021_J.Pharm.Sci__Assessment of drug-drug interaction and optimization in capecitabine and irinotecan combination regimen using a physiologically based pharmacokinetic model
Sakai_2021_Life.Sci_284_119896Arylacetamide deacetylase as a determinant of the hydrolysis and activation of abiraterone acetate in mice and humans
Sakata_2021_J.Biochem_169_363Double prenylation of SNARE protein Ykt6 is required for lysosomal hydrolase trafficking
Salau_2021_Arch.Physiol.Biochem__1Vanillin improves glucose homeostasis and modulates metabolic activities linked to type 2 diabetes in fructose-streptozotocin induced diabetic rats
Salau_2021_J.Food.Biochem__e13641Ferulic acid promotes muscle glucose uptake and modulate dysregulated redox balance and metabolic pathways in ferric-induced pancreatic oxidative injury
Salau_2021_Neurosci.Res_169_57Kolaviron stimulates glucose uptake with concomitant modulation of metabolic activities implicated in neurodegeneration in isolated rat brain, without perturbation of tissue ultrastructural morphology
Salau_2021_Reprod.Toxicol__Vanillin Exerts Therapeutic Effects against Hyperglycemia-Altered Glucose Metabolism and Purinergic Activities in Testicular Tissues of Diabetic Rats
Salau_2021_Sci.Rep_11_18724Vanillin modulates activities linked to dysmetabolism in psoas muscle of diabetic rats
Salbini_2021_Molecules_26_Oxidative Stress and Multi-Organel Damage Induced by Two Novel Phytocannabinoids, CBDB and CBDP, in Breast Cancer Cells
Saleem_2021_Bioorg.Chem_118_105457Deep eutectic solvent mediated synthesis of 3,4-dihydropyrimidin-2(1H)-ones and evaluation of biological activities targeting neurodegenerative disorders
Saleem_2021_Food.Chem.Toxicol__112348A comprehensive phytochemical, biological, toxicological and molecular docking evaluation of Suaeda fruticosa (L.) Forssk.: An edible halophyte medicinal plant
Saleem_2021_Food.Chem.Toxicol__112404Investigation into the biological properties, secondary metabolites composition, and toxicity of aerial and root parts of Capparis spinosa L.: An important medicinal food plant
Saleem_2021_Front.Pharmacol_12_664832Pharmacological Screening of Viola odorata L. for Memory-Enhancing Effect via Modulation of Oxidative Stress and Inflammatory Biomarkers
Saleem_2021_Metab.Brain.Dis_36_1231Antiparkinsonian activity of Cucurbita pepo seeds along with possible underlying mechanism
Saleem_2021_Metab.Brain.Dis_36_889Neuroprotective potential of Malva neglecta is mediated via down-regulation of cholinesterase and modulation of oxidative stress markers
Saleem_2021_Nat.Prod.Res_35_664New insights into the phytochemical composition, enzyme inhibition and antioxidant properties of desert cotton (Aerva javanica (Bum.f) Shult. -Amaranthaceae)
Saleh_2021_Curr.Rev.Clin.Exp.Pharmacol_16_139Berberine Nanoencapsulation Attenuates Hallmarks of Scoplomine Induced Alzheimer's-Like Disease in Rats
Sales_2021_Bioprocess.Biosyst.Eng__Improved production of biocatalysts by Yarrowia lipolytica using natural sources of the biopolyesters cutin and suberin, and their application in hydrolysis of poly (ethylene terephthalate) (PET)
Sales_2021_World.J.Microbiol.Biotechnol_37_116A critical view on the technology readiness level (TRL) of microbial plastics biodegradation
Salih_2021_Cogn.Neuropsychiatry__1Imagine that: cholinesterase inhibitor treatment of complex visual hallucinations of unknown aetiology
Sallam_2021_Chem.Biodivers_18_e2000957Westalsan: A New Acetylcholine Esterase Inhibitor from the Endophytic Fungus Westerdykella nigra
Salvati_2021_J.Colloid.Interface.Sci_588_767Enzymatic hydrolysis of monoacylglycerols and their cyclopropanated derivatives: Molecular structure and nanostructure determine the rate of digestion
Samad_2021_Biol.Trace.Elem.Res__Inhibitory Effects of Selenium on Arsenic-Induced Anxiety-/Depression-Like Behavior and Memory Impairment
Samad_2021_Environ.Sci.Pollut.Res.Int__D-galactose induced dysfunction in mice hippocampus and the possible antioxidant and neuromodulatory effects of selenium
Samad_2021_Metab.Brain.Dis__Reserpine-induced altered neuro-behavioral, biochemical and histopathological assessments prevent by enhanced antioxidant defence system of thymoquinone in mice
Samad_2021_Pak.J.Pharm.Sci_34_1499Tryptophan lessens reserpine induced anxiety, depression and memory impairment by modulating oxidative stress and serotonergic activity
Samson_2021_Brain.Res__147565The impairment of motor coordination following chronic carbamazepine-levetiracetam adjunctive treatment with evidence of corticocerebellar toxicity in male Wistar rats
Sanchez Montero _2021_Eur.J.Pharmacol__173875Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease
Sanchez-Martinez_2021_Food.Funct_12_302In vitro neuroprotective potential of terpenes from industrial orange juice by-products
Sanchez_2021_Methods.Mol.Biol_2309_191Evaluation of Bioactivity of Strigolactone-Related Molecules by a Quantitative Luminometer Bioassay
Sanchis_2021_Amino.Acids__Rational design and synthesis of modified natural peptides from Boana pulchella (anura) as acetylcholinesterase inhibitors and antioxidants
Sander_2021_Front.Microbiol_12_672727Metaproteomic Discovery and Characterization of a Novel Lipolytic Enzyme From an Indian Hot Spring
Sandhu_2021_Mol.Divers__Machine learning-based modeling to predict inhibitors of acetylcholinesterase
Sandoval-Gio_2021_Bull.Environ.Contam.Toxicol__Effect of Benzophenone-3 to Acetylcholinesterase and Antioxidant System in Zebrafish (Danio rerio) Embryos
Sangaleti_2021_Front.Immunol_12_613979The Cholinergic Drug Galantamine Alleviates Oxidative Stress Alongside Anti-inflammatory and Cardio-Metabolic Effects in Subjects With the Metabolic Syndrome in a Randomized Trial
Sankorrakul_2021_J.Neurochem__Is there a role for the p75 neurotrophin receptor in mediating degeneration during oxidative stress and after hypoxia?
Sanooghi_2021_Basic.Clin.Neurosci_12_315Differentiation of Mesenchymal Stem Cells Derived From Human Adipose Tissue Into Cholinergic-like Cells: An in Vitro Study
Santillan_2021_Environ.Sci.Pollut.Res.Int__Exposure to environmental concentrations of fipronil induces biochemical changes on a neotropical freshwater fish
Santillan_2021_Pestic.Biochem.Physiol_177_104876Multibiomarker responses and bioaccumulation of fipronil in Prochilodus lineatus exposed to spiked sediments: Oxidative stress and antioxidant defenses
Santilli_2021_Neurologist_26_175MuSK Myasthenia Gravis Presenting with Bilateral Vocal Cord Abduction Paresis: A Case Report and Literature Review
Santillo_2021_SLAS.Discov__High-throughput screening for identifying acetylcholinesterase inhibitors: Insights on novel inhibitors and the use of liver microsomes
Santos_2021_Aquat.Toxicol_235_105814Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure
Santos_2021_Aquat.Toxicol_241_106003Influence of salinity on the toxicity of copper and cadmium to Zebrafish embryos
Santos_2021_Chemosphere_277_130262Single and combined acute and subchronic toxic effects of microplastics and copper in zebrafish (Danio rerio) early life stages
Santos_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_252_109225Acetylcholinesterase from the charru mussel Mytella charruana: kinetic characterization, physicochemical properties and potential as in vitro biomarker in environmental monitoring of mollusk extraction areas
Santos_2021_Environ.Toxicol.Chem__Sub-Chronic Exposure to Environmental Concentrations of Chlorpyrifos Affect Swimming Activity of Rainbow Trout Larvae
Santos_2021_Rev.Bras.Parasitol.Vet_30_e002221Effects of essential oils on native and recombinant acetylcholinesterases of Rhipicephalus microplus
Saputra_2021_Int.J.Mol.Sci_22_Co-Treatment of Copper Oxide Nanoparticle and Carbofuran Enhances Cardiotoxicity in Zebrafish Embryos
Saquib_2021_J.Appl.Toxicol__Carbofuran cytotoxicity, DNA damage, oxidative stress, and cell death in human umbilical vein endothelial cells: Evidence of vascular toxicity
Sarangi_2021_Neurol.India_69_252Chronic Neurological Disorders: Genetic and Epigenetic Markers for Monitoring of Pharmacotherapy
Saraswat_2021_Cannabis.Cannabinoid.Res__Cannabidiol Inhibits In Vitro Human Liver Microsomal Metabolism of Remdesivir: A Promising Adjuvant for COVID-19 Treatment
Saravanakumar_2021_Plants.(Basel)_10_Phytochemical Composition, Antioxidant, and Enzyme Inhibition Activities of Methanolic Extracts of Two Endemic Onosma Species
Saravanan_2021_J.Biomol.Struct.Dyn__1Probing the intermolecular interactions, binding affinity, charge density distribution and dynamics of silibinin in dual targets AChE and BACE1: QTAIM and molecular dynamics perspective
Saravanan_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_259_119856Binding studies of known molecules with acetylcholinesterase and bovine serum albumin: A comparative view
Sari_2021_Drug.Dev.Res__Potential of nafimidone derivatives against co-morbidities of epilepsy: In vitro, in vivo, and in silico investigations
Sartini_2021_Hum.Cell_34_1929Differential immunohistochemical expression of paraoxonase-2 in actinic keratosis and squamous cell carcinoma
Sasaki_2021_Arterioscler.Thromb.Vasc.Biol_41_360Novel LCAT (Lecithin:Cholesterol Acyltransferase) Activator DS-8190a Prevents the Progression of Plaque Accumulation in Atherosclerosis Models
Sasidharan_2021_J.Enzyme.Inhib.Med.Chem_36_188Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations
Sathe_2021_J.Pediatr.Gastroenterol.Nutr_72_18Evaluation of the Effectiveness of In-line Immobilized Lipase Cartridge in Enterally Fed Patients With Cystic Fibrosis
Sato_2021_Medicine.(Baltimore)_100_e27212The association between sarcopenia and endotoxin in patients with alcoholic cirrhosis
Sato_2021_Toxicology__152679Non-linear model analysis of the relationship between cholinesterase activity in rats exposed to 2, 2-dichlorovinyl dimethylphosphate (dichlorvos) and its metabolite concentrations in urine
Savall_2021_Neurosci.Lett__135697Potential role of a newly AChE reactivator in the depressive-like behavior induced by malathion
Savickaite_2021_Int.J.Biol.Macromol_168_261Study of individual domains' functionality in fused lipolytic biocatalysts based on Geobacillus lipases and esterases
Savickaite_2021_Int.J.Biol.Macromol__Immobilized GDEst-95, GDEst-lip and GD-95RM lipolytic enzymes for continuous flow hydrolysis and transesterification reactions
Saw_2021_Cardiovasc.Diabetol_20_50Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications
Sawarng_2021_J.Environ.Public.Health_2021_6746367Effectiveness of a Participatory Program on Pesticide Use Behavior and Blood Cholinesterase Levels in Chiang Mai Province, Northern Thailand
Sawyer_2021_Toxicol.In.Vitro__105256Acute and long-term effects of VX in rat brain cell aggregate culture
Saxena_2021_Chem.Biol.Interact__109499Conjugates of Human Serum Butyrylcholinesterase and Nerve Agents are Behaviorally Safe in Rhesus Macaques
Schaltenberg_2021_Front.Cardiovasc.Med_8_628235Endothelial Lipase Is Involved in Cold-Induced High-Density Lipoprotein Turnover and Reverse Cholesterol Transport in Mice
Scheen_2021_Diabetes.Metab_47_101213DPP-4 inhibition and COVID-19: From initial concerns to recent expectations
Scheiner_2021_ChemPhotoChem_5_149Photopharmacology on Acetylcholinesterase: Novel Photoswitchable Inhibitors with Improved Pharmacological Profiles
Scheiner_2021_J.Med.Chem_64_9302Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model
Schenkmayerova_2021_Nat.Commun_12_3616Engineering the protein dynamics of an ancestral luciferase
Schepetkin_2021_Biomolecules_11_Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential
Schick_2021_BMJ.Open_11_e050501Prospective, observational, single-centre cohort study with an independent control group matched for age and sex aimed at investigating the significance of cholinergic activity in patients with schizophrenia: study protocol of the CLASH-study
Schilcher_2021_Int.J.Mol.Sci_22_Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL
Schluep_2021_Insects_12_Metabolic Resistance in Permethrin-Resistant Florida Aedes aegypti (Diptera: Culicidae)
Schmidt_2021_Burns_47_863Point-of-care measured serum cholinesterase activity predicts patient outcome following severe burns
Schmitz_2021_Bioresour.Technol_343_126114Lignocellulose degradation for the bioeconomy: The potential of enzyme synergies between xylanases, ferulic acid esterase and laccase for the production of arabinoxylo-oligosaccharides
Schnapp_2021_ChemMedChem_16_630A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein
Schnitzler_2021_Mar.Pollut.Bull_163_111950Lensless digital holographic microscopy as an efficient method to monitor enzymatic plastic degradation
Schopfer_2021_PLoS.One_16_e0254450Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides
Schreiner_2021_Front.Pharmacol_12_755941Is Our Natural Food Our Homeostasis? Array of a Thousand Effect-Directed Profiles of 68 Herbs and Spices
Schuiten_2021_ACS.Catal_11_6113Promiscuous Dehalogenase Activity of the Epoxide Hydrolase CorEH from Corynebacterium sp. C12
Schumacher_2021_Neuroimage.Clin_30_102604In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies
Schwaminger_2021_Nanoscale.Adv_3_4395Immobilization of PETase enzymes on magnetic iron oxide nanoparticles for the decomposition of microplastic PET
Schwarthoff_2021_Bioorg.Med.Chem_46_116355Evaluation of gamma-carboline-phenothiazine conjugates as simultaneous NMDA receptor blockers and cholinesterase inhibitors
Schwarz_2021_Biomolecules_11_Revisiting Jatropha curcas Monomeric Esterase: A Dienelactone Hydrolase Compatible with the Electrostatic Catapult Model
Schwenk_2021_J.Physiol_599_2639Building of AMPA-type glutamate receptors in the endoplasmic reticulum and its implication for excitatory neurotransmission
Scott_2021_Am.J.Trop.Med.Hyg__Characterization of Pyrethroid Resistance Mechanisms in Aedes aegypti from the Florida Keys
Scuteri_2021_Eur.J.Clin.Pharmacol_77_241Pattern of treatment of behavioural and psychological symptoms of dementia and pain: evidence on pharmacoutilization from a large real-world sample and from a centre for cognitive disturbances and dementia
Sebastian_2021_Physiol.Genomics__The role of resistance to inhibitors of cholinesterase 8b in the control of heart rate
Seguy_2021_Pharmaceutics_13_Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer's Disease Treatment
Seibel_2021_Curr.Alzheimer.Res__Effects of Spices (Saffron, Rosemary, Cinnamon, Turmeric and Ginger) in Alzheimer's Disease
Seibert_2021_Alzheimers.Res.Ther_13_131Efficacy and safety of pharmacotherapy for Alzheimer's disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials
Sekovanic_2021_Biochem.Med.(Zagreb)_31_010901Pre-amplification as a method for improvement of quantitative RT-PCR analysis of circulating miRNAs
Sellami_2021_Saudi.J.Biol.Sci_28_6365Impacts of nanoparticles and phosphonates in the behavior and oxidative status of the mediterranean mussels (Mytilus galloprovincialis)
Selonen_2021_Environ.Res__111495Exploring the impacts of microplastics and associated chemicals in the terrestrial environment - Exposure of soil invertebrates to tire particles
Selvaraj_2021_Cells_10_3454The Novel Monoacylglycerol Lipase Inhibitor MJN110 Suppresses Neuroinflammation, Normalizes Synaptic Composition and Improves Behavioral Performance in the Repetitive Traumatic Brain Injury Mouse Model
Senga_2021_J.Biochem_169_207Multiple structural states of Ca2+-regulated PET hydrolase, Cut190, and its correlation with activity and stability
Senizza_2021_Food.Funct_12_3443Metabolomic profiling and biological properties of six Limonium species: novel perspectives for nutraceutical purposes
Senocak_2021_J.Biochem.Mol.Toxicol__e22969Novel amino acid Schiff base Zn(II) complexes as new therapeutic approaches in diabetes and Alzheimer's disease: Synthesis, characterization, biological evaluation, and molecular docking studies
Senol Deniz_2021_Molecules_26_Outlining In Vitro and In Silico Cholinesterase Inhibitory Activity of Twenty-Four Natural Products of Various Chemical Classes: Smilagenin, Kokusaginine, and Methyl Rosmarinate as Emboldening Inhibitors
Serpell_2021_J.Mol.Biol_433_167231AlphaFold: A Special Issue and A Special Time for Protein Science
Serrano_2021_J.Acad.Consult.Liaison.Psychiatry_62_285The Use of Physostigmine in the Diagnosis and Treatment of Anticholinergic Toxicity After Olanzapine Overdose: Literature Review and Case Report
Sesham_2021_Bioinformation_17_132Molecular modeling, docking and dynamics analysis of lipid droplet associated enzyme Ypr147cp from Saccharomyces cerevisiae
Sever_2021_Arch.Pharm.(Weinheim)__e2100294Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds
Shabbir_2021_Front.Physiol_12_780255Bacillus thuringiensis and Chlorantraniliprole Trigger the Expression of Detoxification-Related Genes in the Larval Midgut of Plutella xylostella
Shabbir_2021_Toxins.(Basel)_13_Assessing the Single and Combined Toxicity of Chlorantraniliprole and Bacillus thuringiensis (GO33A) against Four Selected Strains of Plutella xylostella (Lepidoptera: Plutellidae), and a Gene Expression Analysis
Shah_2021_J.Biomol.Struct.Dyn__1Insights into the structural requirements of triazole derivatives as promising DPP IV inhibitors: computational investigations
Shah_2021_J.Tradit.Chin.Med_41_349Efficacy of Silene arenosa extract on acetylcholinesterase in Bungarus sindanus (krait) venom
Shah_2021_Sensors.(Basel)_21_Colorimetric Detection of Organophosphate Pesticides Based on Acetylcholinesterase and Cysteamine Capped Gold Nanoparticles as Nanozyme
Shaha_2021_Curr.Microbiol__Characterization of an Esterase Producing Bacterium from the Gut of Chironomus circumdatus (Bloodworms) and its Ability to Use Modified Phthalates
Shahrivar-Gargari_2021_Arch.Pharm.(Weinheim)__e2000453Hybridization-based design of novel anticholinesterase indanone-carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies
Shaikh_2021_Bioorg.Chem_110_104770Design, synthesis and evaluation of dihydropyranoindole derivatives as potential cholinesterase inhibitors against Alzheimer's disease
Shaikh_2021_Bioorg.Chem_116_105397Synthesis, characterization, in vitro cholinesterase and hRBCs hemolysis assay and computational evaluation of novel 2,3,4,5-tetrahydrobenzothiazepine appended alpha-aminophosphonates
Shaikh_2021_J.Biomol.Struct.Dyn__1Design, synthesis and biological evaluation of novel antipyrine based alpha-aminophosphonates as anti-Alzheimer and anti-inflammatory agent
Shaikh_2021_Oxid.Med.Cell.Longev_2021_6347792Natural Products in Therapeutic Management of Multineurodegenerative Disorders by Targeting Autophagy
Shakil_2021_EXCLI.J_20_1597Molecular interaction of inhibitors with human brain butyrylcholinesterase
Shamsi_2021_SAR.QSAR.Environ.Res_32_745A modified binary particle swarm optimization with a machine learning algorithm and molecular docking for QSAR modelling of cholinesterase inhibitors
Shan_2021_Enzyme.Microb.Technol_149_109832Conjugation with inulin improves the environmental stability of haloalkane dehalogenase DhaA
Shang_2021_Biomolecules_11_Lipoprotein Lipase and Its Delivery of Fatty Acids to the Heart
Shaposhnikova_2021_Crystals_11_1052Stabilization of Haloalkane Dehalogenase Structure by Interfacial Interaction with Ionic Liquids
Shariati_2021_Biodegradation__Degradation of dibutyl phthalate by Paenarthrobacter sp. Shss isolated from Saravan landfill, Hyrcanian Forests, Iran
Sharif_2021_Biorxiv__Structural mechanism of CARD8 regulation by DPP9
Sharif_2021_Immunity__Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment
Sharma_2021_ACS.Appl.Bio.Mater_4_2026Binary Prodrug of Dichloroacetic Acid and Doxorubicin with Enhanced Anticancer Activity
Sharma_2021_Biol.Trace.Elem.Res__Distribution of Fluoride in Plasma, Brain, and Bones and Associated Oxidative Damage After Induced Chronic Fluorosis in Wistar Rats
Sharma_2021_Clin.Psychopharmacol.Neurosci_19_470Efficacy of Ulinastatin and Sulforaphane Alone or in Combination in Rat Model of Streptozotocin Diabetes Induced Vascular Dementia
Sharma_2021_Drug.Metab.Pers.Ther__Consumption of Ashtanga Ghrita (clarified cow butter added with herb extracts) improves cognitive dysfunction induced by scopolamine in rats via regulation of acetylcholinesterase activity and oxidative stress
Sharma_2021_Free.Radic.Res__1Oxidative damage in the liver and brain of the rats exposed to frequency-dependent radiofrequency electromagnetic exposure: Biochemical and histopathological evidence
Sharma_2021_J.Basic.Clin.Physiol.Pharmacol__Behavioral and biochemical investigations to explore the efficacy of quercetin and folacin in experimental diabetes induced vascular endothelium dysfunction and associated dementia in rats
Sharma_2021_Molecules_26_Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32
Sharma_2021_Talanta_221_121267Sensing platform for pico-molar level detection of ethyl parathion using Au-Ag nanoclusters based enzymatic strategy
Sharma_2021_Toxicol.Rep_8_223Neuroprotective potential of hydroethanolic hull extract of Juglans regia L. on isoprenaline induced oxidative damage in brain of Wistar rats
Sharmeen_2021_Chem.Biodivers__GC/MS Profiling, In Vitro and In Silico Pharmacological Screening and Principal Component Analysis of Essential Oils from Three Exotic and Two Endemic Plants from Mauritius
Shcherbitskaia_2021_Cells_10_Prenatal Hyperhomocysteinemia Induces Glial Activation and Alters Neuroinflammatory Marker Expression in Infant Rat Hippocampus
Sheedlo_2021_Biochemistry__Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA
Shen_2021_ACS.Appl.Mater.Interfaces__Detection of Carboxylesterase 1 and Chlorpyrifos with ZIF-8 Metal-Organic Frameworks Using a Red Emission BODIPY-Based Probe
Shen_2021_Fundam.Clin.Pharmacol_35_432Remdesivir potently inhibits carboxylesterase-2 through covalent modifications: signifying strong drug-drug interactions
Shen_2021_Hepatol.Commun__The COVID-19 medicine remdesivir is therapeutically activated by carboxylesterase-1 AND excessive hydrolysis increases cytotoxicity
Sheng_2021_J.Insect.Sci_21_Evaluation of Sensitivity to Phoxim and Cypermethrin in an Endoparasitoid, Meteorus pulchricornis (Wesmael) (Hymenoptera: Braconidae), and Its Parasitization Efficiency Under Insecticide Stress
Sheyn_2021_Int.Urogynecol.J__Evaluation of the relationship of cholinergic metabolites in urine and urgency urinary incontinence
Shi_2021_Animal.Model.Exp.Med_4_418Heterozygous lipoprotein lipase knockout mice exhibit impaired hematopoietic stem/progenitor cell compartment
Shi_2021_Clin.Pharmacol.Ther__Plasma carboxylesterase 1 predicts methylphenidate exposure: a proof-of-concept study using plasma protein biomarker for hepatic drug metabolism
Shi_2021_Eur.J.Drug.Metab.Pharmacokinet_46_129Rapalogues as hCES2A Inhibitors: In Vitro and In Silico Investigations
Shi_2021_Hepatol.Int__Mesenchymal stem cell therapy in decompensated liver cirrhosis: a long-term follow-up analysis of the randomized controlled clinical trial
Shi_2021_J.Agric.Food.Chem_69_2245Enhanced Extracellular Production of IsPETase in Escherichia coli via Engineering of the pelB Signal Peptide
Shi_2021_J.Healthc.Eng_2021_7563383Detoxification II Prescription Suppresses the Th-17/IL-17 Inflammatory Axis to Improve the Liver Function of ACLF-Rats via Inactivating the P38MAPK Pathway
Shi_2021_J.Zhejiang.Univ.Sci.B_22_204Expression of Drosophila melanogaster acetylcholinesterase (DmAChE) gene splice variants in Pichia pastoris and evaluation of its sensitivity to organophosphorus pesticides
Shi_2021_Toxicol.Lett_338_32Repeated low-dose exposures to sarin disrupted the homeostasis of phospholipid and sphingolipid metabolism in guinea pig hippocampus
Shiba_2021_Eur.Heart.J.Acute.Cardiovasc.Care__Serum cholinesterase as a prognostic biomarker for acute heart failure
Shih_2021_Toxicol.Appl.Pharmacol__115443The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs
Shim_2021_Front.Aging.Neurosci_13_665400Decreased Exosomal Acetylcholinesterase Activity in the Plasma of Patients With Parkinson's Disease
Shimura_2021_BMC.Neurol_21_61Rivastigmine improves dual-task gait velocity in patients with Alzheimer's disease
Shin_2021_Int.J.Biol.Macromol_168_403Biochemical characterization and molecular docking analysis of novel esterases from Sphingobium chungbukense DJ77
Shoja_2021_Cell.Biochem.Biophys_79_87Effect of Tween Type Non-Ionic Detergent on the Activity of Lipase of Pseudomonas aeruginosa
Shortall_2021_Cells_10_Study of ALDH from Thermus thermophilus-Expression, Purification and Characterisation of the Non-Substrate Specific, Thermophilic Enzyme Displaying Both Dehydrogenase and Esterase Activity
Shuchi_2021_Neurosci.Lett__136294Neuromodulatory potential of Asparagus racemosus and its bioactive molecule Shatavarin IV by enhancing synaptic acetylcholine level and nAChR activity
Shukur_2021_Arch.Pharm.(Weinheim)__e2000467Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease
Shunan_2021_Biomed.Pharmacother_137_111369Neuroprotective effect of Betalain against AlCl(3)-induced Alzheimer's disease in Sprague Dawley Rats via putative modulation of oxidative stress and nuclear factor kappa B (NF-kappaB) signaling pathway
Shyong_2021_J.Pharmacol.Exp.Ther__Enhancing target tissue levels and diminishing plasma clearance of ionizing zwitterionic antidotes in organophosphate exposures
Siddiqui_2021_Biomed.Pharmacother_144_112250Mechanistic role of boswellic acids in Alzheimer's disease: Emphasis on anti-inflammatory properties
Siddiqui_2021_Neuropharmacol__108662Linagliptin, a DPP-4 inhibitor, ameliorates Abeta (1-42) peptides induced neurodegeneration and brain insulin resistance (BIR) via insulin receptor substrate-1 (IRS-1) in rat model of Alzheimer's disease
Siebert_2021_J.Sci.Food.Agric__Enzymatic Hydrolysis of Kaempferol 3-O-(2'''-O-sinapoyl-beta-sophoroside), the Key Bitter Compound of Rapeseed (Brassica napus L.) Protein Isolate
Siebert_2021_Talanta_224_121773Dual electrophoretically-mediated microanalysis in multiple injection mode for the simultaneous determination of acetylcholinesterase and alpha-glucosidase activity applied to selected polyphenols
Silakari_2021_ACS.Chem.Neurosci__Systematic In Silico Design, Synthesis, and Biological Studies of Some Novel 1,4-Benzoquinone Derivatives for the Prospective Management of Cognitive Decline
Silman_2021_Prog.Biophys.Mol.Biol_162_41The multiple biological roles of the cholinesterases
Silman_2021_Protein.Sci__Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif
Silva_2021_Biology.(Basel)_10_Asparagopsis armata Exudate Cocktail: The Quest for the Mechanisms of Toxic Action of an Invasive Seaweed on Marine Invertebrates
Silva_2021_Bioorg.Chem_108_1046497-Amine-spiro[chromeno[4,3-b]quinoline-6,1'-cycloalkanes]: Synthesis and cholinesterase inhibitory activity of structurally modified tacrines
Silva_2021_Environ.Sci.Pollut.Res.Int__Protective effect of gamma-oryzanol against manganese-induced toxicity in Drosophila melanogaster
Silva_2021_Environ.Toxicol.Chem_40_272Biomarker Responses of the Clam Ruditapes decussatus Exposed to a Complex Mixture of Environmental Stressors under the Influence of an Urban Wastewater-Treatment Plant
Silva_2021_Food.Chem.X_12_100171Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits
Silveira_2021_J.Phys.Chem.B__Transition Path Sampling Study of the Feruloyl Esterase Mechanism
Sim_2021_Front.Neurosci_15_708547Role of DPP-4 and SGLT2 Inhibitors Connected to Alzheimer Disease in Type 2 Diabetes Mellitus
Simeonova_2021_Molecules_26_A Novel Galantamine-Curcumin Hybrid as a Potential Multi-Target Agent against Neurodegenerative Disorders
Simonsen_2021_Toxicol.Sci__The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL/6 Mice
Sinan_2021_Antioxidants.(Basel)_10_1570LC-MS Based Analysis and Biological Properties of Pseudocedrela kotschyi (Schweinf.) Harms Extracts: A Valuable Source of Antioxidant, Antifungal, and Antibacterial Compounds
Sinan_2021_Antioxidants.(Basel)_10_1771Exploring the Chemical Profiles and Biological Values of Two Spondias Species (S. dulcis and S. mombin): Valuable Sources of Bioactive Natural Products
Sinan_2021_Antioxidants.(Basel)_10_2003LC-MS/HRMS Analysis, Anti-Cancer, Anti-Enzymatic and Anti-Oxidant Effects of Boerhavia diffusa Extracts: A Potential Raw Material for Functional Applications
Sinan_2021_Biomolecules_11_Deeper Insights on Alchornea cordifolia (Schumach. & Thonn.) Mll.Arg Extracts: Chemical Profiles, Biological Abilities, Network Analysis and Molecular Docking
Sinan_2021_Chem.Biodivers__Biological insights and NMR metabolic profiling of different extracts of Spermacoce verticillata (L.) G. Mey
Sinan_2021_Chem.Biodivers__2A prospective of multiple biopharmaceutical activities of procyanidins-rich Uapaca togoensis Pax extracts: HPLC-ESI-TOF-MS coupled with bioinformatics analysis
Sinan_2021_J.Pharm.Biomed.Anal_203_114184NMR and LC-MS(n) coupled with pharmacological network analysis for the assessment of phytochemical content and biopharmaceutical potential of Carapa procera extracts
Sinclair_2021_J.Neuropsychiatry.Clin.Neurosci__appineuropsych21040103Possible Contribution of Altered Cholinergic Activity in the Visual Cortex in Visual Hallucinations in Parkinson's Disease
Sine_2021_Arch.Environ.Occup.Health__1Measuring butyrylcholinesterase activity and hematological parameters in farmers exposed to pesticides: a case and control study from Morocco
Singh_2021_ACS.Omega_6_7165Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain
Singh_2021_Arch.Microbiol_204_105Rhizophagus proliferus genome sequence reiterates conservation of genetic traits in AM fungi, but predicts higher saprotrophic activity
Singh_2021_Bioorg.Med.Chem_46_116385Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease
Singh_2021_Chem.Res.Toxicol__New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation
Singh_2021_Chemistry_27_5737Paraoxonase Mimic by a Nanoreactor Aggregate Containing Benzimidazolium Calix and l-Histidine: Demonstration of the Acetylcholine Esterase Activity
Singh_2021_Curr.Rev.Clin.Exp.Pharmacol__Investigating Neuroprotective Potential of Berberine, Levetiracetam and Their Combination in The Management of Alzheimer's Disease Utilizing Drug Repurposing Strategy
Singh_2021_Environ.Sci.Pollut.Res.Int__Therapeutic effects of biochanin A, phloretin, and epigallocatechin-3-gallate in reducing oxidative stress in arsenic-intoxicated mice
Singh_2021_Eur.J.Med.Chem_215_113278A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease
Singh_2021_Eur.J.Neurosci__The loss of enzymatic activity of the PHARC associated lipase ABHD12 results in increased phagocytosis that causes neuroinflammation
Singh_2021_Eur.J.Pharmacol__17387616-Substituted steroids alleviate LPS-induced neurodegenerative disorders in rats
Singh_2021_Neurotox.Res__Quercetin Exhibits alpha7nAChR/Nrf2/HO-1-Mediated Neuroprotection Against STZ-Induced Mitochondrial Toxicity and Cognitive Impairments in Experimental Rodents
Singh_2021_RSC.Med.Chem_12_1142Human carboxylesterases and fluorescent probes to image their activity in live cells
Singha_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_252_109223Influence of dietary emamectin benzoate on the biological responses of monosex (all-male) Oreochromis niloticus (L.) fries
Sirichaiwetchakoon_2021_Evid.Based.Complement.Alternat.Med_2021_2703138Butea superba Roxb. Extract Ameliorates Scopolamine-Induced Cognitive and Memory Impairment in Aged Male Rats
Sirinupong_2021_Int.J.Food.Sci_2021_2213814Hydrolase-Treated Royal Jelly Attenuates H(2)O(2)- and Glutamate-Induced SH-SY5Y Cell Damage and Promotes Cognitive Enhancement in a Rat Model of Vascular Dementia
Sirish_2021_Front.Physiol_12_793171The Critical Roles of Proteostasis and Endoplasmic Reticulum Stress in Atrial Fibrillation
Sirwi_2021_Antioxidants.(Basel)_10_Umuhengerin Neuroprotective Effects in Streptozotocin-Induced Alzheimer's Disease Mouse Model via Targeting Nrf2 and NF-Kbeta Signaling Cascades
Sisaphaithong_2021_Plant.Signal.Behav__2009998Localized expression of the Dwarf14-like2a gene in rice roots on infection of arbuscular mycorrhizal fungus and hydrolysis of rac-GR24 by the encoded protein
Sisila_2021_Appl.Biochem.Biotechnol_193_19Esterification of Polymeric Carbohydrate Through Congener Cutinase-Like Biocatalyst
Sivapalasingam_2021_J.Infect.Dis__Human Monoclonal Antibody Cocktail for the Treatment or Prophylaxis of Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV)
Sivapurapu_2021_Anesth.Essays.Res_15_457Myasthenia Gravis and COVID-19 - A Clinical Checkmate
Siwaraman_2021_CNS.Neurol.Disord.Drug.Targets__Acetylcholinesterase Enzyme Inhibitor Molecules with Therapeutic Potential for Alzheimer's Disease
Skedsmo_2021_Neuromuscul.Disord_31_56Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D
Skellam_2021_Nat.Prod.Rep__Biosynthesis of fungal polyketides by collaborating and trans-acting enzymes
Skolnick_2021_J.Chem.Inf.Model__AlphaFold 2: Why It Works and Its Implications for Understanding the Relationships of Protein Sequence, Structure, and Function
Skomal_2021_Environ.Res__112163Concurrent urinary organophosphate metabolites and acetylcholinesterase activity in Ecuadorian adolescents
Skrzypek_2021_Bioorg.Chem_107_104617Biological evaluation and molecular docking of novel 1,3,4-thiadiazole-resorcinol conjugates as multifunctional cholinesterases inhibitors
Sladek_2021_Neuropharmacol_185_108455Modulation of single cell circadian response to NMDA by diacylglycerol lipase inhibition reveals a role of endocannabinoids in light entrainment of the suprachiasmatic nucleus
Smach_2021_J.Med.Food_24_645Maillard Reaction Products and Phenolic Compounds from Roasted Peanut Flour Extracts Prevent Scopolamine-Induced Amnesia Via Cholinergic Modulation and Antioxidative Effects in Mice
Smaili_2021_Nat.Prod.Res__1Chemical constituents and anticholinesterase activity of the essential oil of Algerian Elaeoselinum thapsioides (desf.) maire
Smith_2021_Acta.Biomater__Organophosphate Detoxification by Membrane-Engineered Red Blood Cells
Soares_2021_Neurochem.Res__The Protective Action of Rubus sp. Fruit Extract Against Oxidative Damage in Mice Exposed to Lipopolysaccharide
Sobolev_2021_Int.J.Mol.Sci_22_Nephrotoxic Effects of Paraoxon in Three Rat Models of Acute Intoxication
Sofela_2021_Clin.Exp.Dermatol__A rare case of lipase hypersecretion syndrome
Sohn_2021_Integr.Med.Res_10_100723Korean traditional herbal formula Soshiho-tang attenuates memory impairment and neuronal damage in mice with amyloid-beta-induced Alzheimer's disease
Sohn_2021_Mol.Neurobiol__Ficus erecta Thunb Leaves Alleviate Memory Loss Induced by Scopolamine in Mice via Regulation of Oxidative Stress and Cholinergic System
Sokolowski_2021_Sci.Total.Environ_794_148593Cellular level response of the bivalve Limecola balthica to seawater acidification due to potential CO(2) leakage from a sub-seabed storage site in the southern Baltic Sea: TiTank experiment at representative hydrostatic pressure
Sola_2021_Environ.Toxicol.Pharmacol_90_103791Cadmium-induced neurotoxic effects on rat basal forebrain cholinergic system through thyroid hormones disruption
Sole_2021_Chemosphere_277_130283Biomarker responses and metabolism in Lumbricus terrestris exposed to drugs of environmental concern, an in vivo and in vitro approach
Sollier_2021_Eur.J.Endocrinol_184_155LIPE-related lipodystrophic syndrome: clinical characteristics and disease modelling using adipose stem cells
Soma_2021_Neurobiol.Learn.Mem_183_107484Acetylcholine from the nucleus basalis magnocellularis facilitates the retrieval of well-established memory
Song_2021_Acta.Pharm.Sin.B_11_3035Recent developments in the medicinal chemistry of single boron atom-containing compounds
Song_2021_Anal.Chem__Sensitivity Dependence on the Crystal Forms of a Fluorescence Quencher for Silicon Quantum Dots and Its Use in Acetylcholinesterase Assay
Song_2021_Cells_10_TSPO Expression Modulatory Effect of Acetylcholinesterase Inhibitor in the Ischemic Stroke Rat Model
Song_2021_Chem.Biol.Interact__109566Carboxylesterase inhibitors from clinically available medicines and their impact on drug metabolism
Song_2021_Food.Funct_12_162Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays
Song_2021_Front.Pharmacol_12_655659Discovery and Characterization of the Biflavones From Ginkgo biloba as Highly Specific and Potent Inhibitors Against Human Carboxylesterase 2
Song_2021_J.Cardiothorac.Surg_16_45Sugammadex is associated with shorter hospital length of stay after open lobectomy for lung cancer: a retrospective observational study
Song_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1181_122922A strategy to discover lead chemome from traditional Chinese medicines based on natural chromatogram-effect correlation (NCEC) and natural structure-effect correlation (NSEC): Mahonia bealei and Mahonia fortunei as a case study
Song_2021_Med.Hypotheses_155_110666SARM1-mediated wallerian degeneration: A possible mechanism underlying organophosphorus-induced delayed neuropathy
Song_2021_Oxid.Med.Cell.Longev_2021_8844455Osthole-Loaded Nanoemulsion Enhances Brain Target in the Treatment of Alzheimer's Disease via Intranasal Administration
Soni_2021_Biotechnol.Appl.Biochem__Trends in lipase engineering for enhanced biocatalysis
Soraya_2021_Arch.Med.Res_52_151Metformin Increases Exosome Biogenesis and Secretion in U87 MG Human Glioblastoma Cells: A Possible Mechanism of Therapeutic Resistance
Souza_2021_Aquat.Toxicol_241_105997Temporal exposure to malathion: Biochemical changes in the Amazonian fish tambaqui, Colossoma macropomum
Spiegel_2021_Int.J.Mol.Sci_23_A Comparison between Enrichment Optimization Algorithm (EOA)-Based and Docking-Based Virtual Screening
Spinelli_2021_Nat.Prod.Res__1Natural multi-target modulators of pathological pathways in Alzheimer's disease isolated from the Rhinella arenarum skin
Spitler_2021_Am.J.Physiol.Endocrinol.Metab__Chronic high fat feeding and prolonged fasting in liver-specific ANGPTL4 knockout mice
Spitler_2021_Sci.Rep_11_7873Regulation of plasma triglyceride partitioning by adipose-derived ANGPTL4 in mice
Srancikova_2021_Andrologia__e14153The effects of testosterone on gene expression of cell-adhesion molecules and scaffolding proteins: The role of sex in early development
Sridhar_2021_J.Biomol.Struct.Dyn__1Synthesis, molecular modelling, in vitro and in vivo evaluation of conophylline inspired novel benzyloxy substituted indole glyoxylamides as potent pancreatic lipase inhibitors
Srivastava_2021_Eur.J.Med.Chem_216_113320Alzheimer's disease and its treatment by different approaches: A review
Stading_2021_Semin.Cancer.Biol__Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implications for human lung cancer
Stage_2021_Alzheimers.Dement.(N.Y)_7_e12168Prescribing cholinesterase inhibitors in mild cognitive impairment-Observations from the Alzheimer's Disease Neuroimaging Initiative
Stalin_2021_Med.Chem__Synthesis, molecular docking and mosquitocidal efficacy of lawsone and its derivatives against the dengue vector Aedes aegypti L. (Diptera: Culicidae)
Stanley_2021_Alzheimers.Dement__The Clinician's Interview-Based Impression of Change (Plus caregiver input) and goal attainment in two dementia drug trials: Clinical meaningfulness and the initial treatment response
Stasilowicz_2021_Int.J.Mol.Sci_22_Combinations of Piperine with Hydroxypropyl-beta-Cyclodextrin as a Multifunctional System
Stavrakov_2021_Molecules_26_Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening
Stazi_2021_Cell.Mol.Life.Sci_79_55Long-term caffeine treatment of Alzheimer mouse models ameliorates behavioural deficits and neuron loss and promotes cellular and molecular markers of neurogenesis
Steffen_2021_Mol.Neurobiol__The gamma-Protocadherins Interact Physically and Functionally with Neuroligin-2 to Negatively Regulate Inhibitory Synapse Density and Are Required for Normal Social Interaction
Stephenson_2021_Eur.J.Med.Chem_213_113135Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma
Stigler_2021_Arch.Toxicol__Post-VX exposure treatment of rats with engineered phosphotriesterases
Stockhoff_2021_Hepatol.Commun__Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS
Stojanovic_2021_J.Ethnopharmacol__114788Lemon balm (Melissa officinalis L.) essential oil and citronellal modulate anxiety-related symptoms - In vitro and in vivo studies
Stojiljkovic_2021_Chem.Biol.Interact__109463Effects of memantine and its metabolite Mrz 2/373 on soman-induced inhibition of acetylcholinesterase in vitro
Stolero_2021_J.Neurochem_158_1412The dialog between neurons and microglia in Alzheimer's disease: The neurotransmitters view
Strodel_2021_J.Mol.Biol_433_167182Energy Landscapes of Protein Aggregation and Conformation Switching in Intrinsically Disordered Proteins
Studzinska-Sroka_2021_Cancers.(Basel)_13_Permeability of Hypogymnia physodes Extract Component-Physodic Acid through the Blood-Brain Barrier as an Important Argument for Its Anticancer and Neuroprotective Activity within the Central Nervous System
Studzinska-Sroka_2021_Pharmaceuticals.(Basel)_14_Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties
Sturve_2021_Mar.Pollut.Bull_173_112964Effects of pesticides and metals on penaeid shrimps in Maputo Bay, Mozambique - A field study
Su_2021_BMC.Genomics_22_548Genome-wide analysis and expression patterns of lipid phospholipid phospholipase gene family in Brassica napus L
Su_2021_Biosens.Bioelectron_194_113598Background-free sensing platform for on-site detection of carbamate pesticide through upconversion nanoparticles-based hydrogel suit
Su_2021_J.Econ.Entomol__Sublethal Effects of Abamectin on the Development, Reproduction, Detoxification Enzyme Activity, and Related Gene Expression of the Oriental Fruit Moth (Lepidoptera: Tortricidae)
Suarez-Lopez_2021_Expo.Health_13_51Associations of acetylcholinesterase inhibition between pesticide spray seasons with depression and anxiety symptoms in adolescents, and the role of sex and adrenal hormones on gender moderation
Suarez-Montenegro_2021_Front.Nutr_8_769617Neuroprotective Potential of Tamarillo (Cyphomandra betacea) Epicarp Extracts Obtained by Sustainable Extraction Process
Suarez_2021_Foods_10_Neuroprotective Effect of Terpenoids Recovered from Olive Oil By-Products
Subahar_2021_Vet.World_14_3065In vitro experiments of Pediculus humanus capitis (Phthiraptera: Pediculidae) resistance to permethrin and 6-paradol in East Jakarta: Detoxification enzyme activity and electron microscopic changes in lice
Suciati_2021_J.Basic.Clin.Physiol.Pharmacol_32_313Acetylcholinesterase inhibitory activity of extract and fractions from the root of Rauvolfia serpentina(L.) Bth.ex Kurz
Suciu_2021_Bioorg.Med.Chem.Lett_53_128414Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation
Sudeep_2021_J.Food.Biochem__e13994A standardized black pepper seed extract containing beta-caryophyllene improves cognitive function in scopolamine-induced amnesia model mice via regulation of brain-derived neurotrophic factor and MAPK proteins
Sufian_2021_J.Exp.Biol__Early suppression of the endocannabinoid degrading enzymes FAAH and MAGL alters locomotor development in zebrafish
Sugasini_2021_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159002Potential role of hepatic lipase in the accretion of docosahexaenoic acid (DHA) by the brain
Suharti_2021_Heliyon_7_e06542Cloning, heterologous expression, and characterization of a novel thioesterase from natural sample
Sui_2021_Adv.Nanobiomed.Res_1_Esterase-activatable and GSH-responsive Triptolide Nano-prodrug for the Eradication of Pancreatic Cancer
Sukumaran_2021_J.Enzyme.Inhib.Med.Chem_36_130Analogues of 2'-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase
Sumra_2021_Environ.Monit.Assess_193_665Biochemical characterization of Aedes aegypti (Linnaeus) (Diptera: Culicidae) resistance to deltamethrin, fipronil, and imidacloprid
Sun_2021_Am.J.Transl.Res_13_9315Early enteral nutrition combined with PSS-based nursing in the treatment of organophosphorus pesticide poisoning
Sun_2021_Behav.Sci.(Basel)_11_Treatment of Parkinson's Disease with Cognitive Impairment: Current Approaches and Future Directions
Sun_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109038A preliminary study on the neurotoxic mechanism of harmine in Caenorhabditis elegans
Sun_2021_Environ.Res__111793An integrated approach using chemical ecological risk assessment and multi-integrated biomarker indexes approach to assess pollution: A case study of Ruditapes philippinarum in four bays on the Shandong Peninsula in China
Sun_2021_Food.Chem.Toxicol_156_112516Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3beta signaling pathway
Sun_2021_Front.Behav.Neurosci_15_594907Melamine Disrupts Acetylcholine-Mediated Neural Information Flow in the Hippocampal CA3-CA1 Pathway
Sun_2021_J.Med.Chem_64_184Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products
Sun_2021_Methods.Enzymol_648_207GRAPE, a greedy accumulated strategy for computational protein engineering
Sun_2021_Mol.Nutr.Food.Res__e2101002Dihydromyricetin Improves Cognitive Impairments in D-galactose-Induced Aging Mice through Regulating Oxidative Stress and Inhibition of Acetylcholinesterase
Sun_2021_Nat.Commun_12_3335Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity
Sundararajan_2021_3.Biotech_11_159Investigation of therapeutic potential of cerium oxide nanoparticles in Alzheimer's disease using transgenic Drosophila
Suner_2021_J.Fluoresc__Versatile Fluorescent Carbon Dots from Citric Acid and Cysteine with Antimicrobial, Anti-biofilm, Antioxidant, and AChE Enzyme Inhibition Capabilities
Sunny_2021_Extremophiles__IND-enzymes: a repository for hydrolytic enzymes derived from thermophilic and psychrophilic bacterial species with potential industrial usage
Suo_2021_Colloids.Surf.B.Biointerfaces_206_111960Enhancing bio-catalytic performance of lipase immobilized on ionic liquids modified magnetic polydopamine
Suttisansanee_2021_Plants.(Basel)_10_Phytochemicals and In Vitro Bioactivities of Aqueous Ethanolic Extracts from Common Vegetables in Thai Food
Suwanhom_2021_Molecules_26_Synthesis, Biological Evaluation, and In Silico Studies of New Acetylcholinesterase Inhibitors Based on Quinoxaline Scaffold
Suzuki_2021_Eur.J.Neurosci_53_796M1 muscarinic acetylcholine receptor-mediated inhibition of GABA release from striatal medium spiny neurons onto cholinergic interneurons
Svob_2021_Pharmgenomics.Pers.Med_14_631Personalizing the Care and Treatment of Alzheimer's Disease: An Overview
Swaraz_2021_Biomed.Pharmacother_141_111859Phytochemical profiling of Blumea laciniata (Roxb.) DC. and its phytopharmaceutical potential against diabetic, obesity, and Alzheimer's
Sylvers-Davie_2021_Am.J.Physiol.Endocrinol.Metab__Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8
Syme_2021_PLoS.One_16_e0245804Which indoor residual spraying insecticide best complements standard pyrethroid long-lasting insecticidal nets for improved control of pyrethroid resistant malaria vectors?
Szafran_2021_Chem.Res.Toxicol__Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice
Szmicsekova_2021_Physiol.Res__Aortic butyrylcholinesterase is reduced in spontaneously hypertensive rats
Tagliaferri_2021_Cureus_13_e15581A Case of COVID-19 Vaccine Causing a Myasthenia Gravis Crisis
Taha_2021_Environ.Sci.Pollut.Res.Int__Alteration in antioxidant status in slow and fast alleles of EPHX1 gene polymorphisms among wood workers
Taha_2021_Int.J.Biol.Macromol__Exploring indole-based-thiadiazole derivatives as potent acetylcholinesterase and butyrylcholinesterase enzyme inhibitors
Taha_2021_J.Complement.Integr.Med__Association of microsomal epoxide hydrolase gene (fast genotype) with lung functions impairment in wood workers
Tahar_2021_Nat.Prod.Res__1Chemical composition, antioxidant and anticholinesterase activity of the essential oil of algerian cachrys sicula L
Taher_2021_Curr.Res.Struct.Biol_3_72Biochemical and Structural Characterization of Two Cif-Like Epoxide Hydrolases from Burkholderia cenocepacia
Takagi_2021_Surg.Today__Clinical outcome of cardiac surgery in patients with remitted or active hepatocellular carcinoma
Takahashi_2021_Behav.Brain.Res__113283Activation of cholinergic system partially rescues olfactory dysfunction-induced learning and memory deficit in mice
Takahashi_2021_Drug.Metab.Pharmacokinet_38_100391Effects of steric hindrance and electron density of ester prodrugs on controlling the metabolic activation by human carboxylesterase
Takahashi_2021_Front.Oncol_11_714527Fluorescence Imaging Using Enzyme-Activatable Probes for Real-Time Identification of Pancreatic Cancer
Takahashi_2021_Int.J.Mol.Sci_22_Multiple Roles for Cholinergic Signaling from the Perspective of Stem Cell Function
Takahashi_2021_J.Clin.Med_10_Prepregnancy Assessment of Liver Function to Predict Perinatal and Postpregnancy Outcomes in Biliary Atresia Patients with Native Liver
Takahashi_2021_aBIOTECH_2_1On improving strigolactone mimics for induction of suicidal germination of the root parasitic plant Striga hermonthica
Takano_2021_Surg.Today__Preoperative serum cholinesterase levels as a risk factor of postoperative complications for the elderly undergoing emergency surgery
Takarada-Iemata_2021_Anat.Sci.Int_96_1Roles of N-myc downstream-regulated gene 2 in the central nervous system: molecular basis and relevance to pathophysiology
Takarada-Iemata_2021_Neurosci.Lett_743_135563Abnormal social behavior and altered gene expression in mice lacking NDRG2
Takemoto_2021_Biochem.Pharmacol__114766m(6)A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2
Takemoto_2021_Chem.Pharm.Bull.(Tokyo)_69_819Molecular Transformation Based on an Innovative Catalytic System
Takenaka_2021_Int.J.Food.Microbiol_353_109299Identification and characterization of extracellular enzymes secreted by Aspergillus spp. involved in lipolysis and lipid-antioxidation during katsuobushi fermentation and ripening
Takeo_2021_ACS.Chem.Neurosci__Mass Spectrometric Enzyme Histochemistry for Choline Acetyltransferase Reveals De Novo Acetylcholine Synthesis in Rodent Brain and Spinal Cord
Takomthong_2021_Pharmaceuticals.(Basel)_14_Multi-Target Actions of Acridones from Atalantia monophylla towards Alzheimer's Pathogenesis and Their Pharmacokinetic Properties
Taktak_2021_J.Egypt.Public.Health.Assoc_96_21Enhanced mosquitocidal efficacy of pyrethroid insecticides by nanometric emulsion preparation towards Culex pipiens larvae with biochemical and molecular docking studies
Tallini_2021_Plants.(Basel)_10_Alkaloid Profiling and Cholinesterase Inhibitory Potential of Crinum amabile Donn. (Amaryllidaceae) Collected in Ecuador
Tamfu_2021_Molecules_26_Non-Alkaloid Cholinesterase Inhibitory Compounds from Natural Sources
Tamoor_2021_Front.Microbiol_12_777727Potential Use of Microbial Enzymes for the Conversion of Plastic Waste Into Value-Added Products: A Viable Solution
Tampio_2021_Int.J.Pharm__120565Improved L-Type Amino Acid Transporter 1 (LAT1)-Mediated Delivery of Anti-Inflammatory Drugs into Astrocytes and Microglia with Reduced Prostaglandin Production
Tan_2021_Comp.Biochem.Physiol.B.Biochem.Mol.Biol__110590Molecular cloning and characterization of an atypical butyrylcholinesterase-like protein in zebrafish
Tan_2021_Comput.Struct.Biotechnol.J_19_869An extracellular lipase from Amycolatopsis mediterannei is a cutinase with plastic degrading activity
Tan_2021_Drug.Des.Devel.Ther_15_1971Inhibitory Effect of Lactococcus lactis subsp. lactis HFY14 on Diphenoxylate-Induced Constipation in Mice by Regulating the VIP-cAMP-PKA-AQP3 Signaling Pathway
Tan_2021_J.Chromatogr.Sci__UHPLC With On-Line Coupled Biochemical Detection for High Throughput Screening of Acetylcholinesterase Inhibitors in Coptidis Rhizoma and Cortex Phellodendri
Tanaka-Kanegae_2021_PLoS.One_16_e0258420A novel in vitro assay model developed to measure both extracellular and intracellular acetylcholine levels for screening cholinergic agents
Tanaka_2021_Int.J.Biol.Macromol_170_343Exploring mutable conserved sites and fatal non-conserved sites by random mutation of esterase from Sulfolobus tokodaii and subtilisin from Thermococcus kodakarensis
Tanaka_2021_J.UOEH_43_197The Role of Brain Methamidophos in Acephate Poisoning in Mice
Tang_2021_ChemMedChem__Novel pyridine-containing sultones: Structure-activity relationship and biological evaluation as selective AChE inhibitors for the treatment of Alzheimer's disease
Tang_2021_DNA.Cell.Biol_40_949The Role of N-myc Downstream-Regulated Gene Family in Glioma Based on Bioinformatics Analysis
Tao_2021_Curr.Res.Pharmacol.Drug.Discov_2_100045Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside
Tassone_2021_Mov.Disord__Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia
Tavian_2021_Eur.J.Transl.Myol__Recurrent N209* ABHD5 mutation in two unreported families with Chanarin Dorfman Syndrome
Tayanloo-Beik_2021_J.Mol.Neurosci__Paeonol Ameliorates Cognitive Deficits in Streptozotocin Murine Model of Sporadic Alzheimer's Disease via Attenuation of Oxidative Stress, Inflammation, and Mitochondrial Dysfunction
Taylor_2021_Annu.Rev.Pharmacol.Toxicol_61_25Cholinergic Capsules and Academic Admonitions
Taylor_2021_J.Neurochem__Ligand design for human acetylcholinesterase and nicotinic acetylcholine receptors, extending beyond the conventional and canonical
Teixeira_2021_Am.J.Physiol.Cell.Physiol_320_C602Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling
Teixeira_2021_Neurochem.Res__Protective Effects of Inosine on Memory Consolidation in a Rat Model of Scopolamine-Induced Cognitive Impairment: Involvement of Cholinergic Signaling, Redox Status, and Ion Pump Activities
Tel-Cayan_2021_Z.Naturforsch.C.J.Biosci__Isolation and characterization of chemical constituents from Chaerophyllum bulbosum roots and their enzyme inhibitory and antioxidant effects
Temiz_2021_Environ.Sci.Pollut.Res.Int__In vivo neurotoxic effects of emamectin benzoate in male mice: evaluation with enzymatic and biomolecular multi-biomarkers
Teo_2021_J.Phys.Chem.B__Modulation of Phospholipid Bilayer Properties by Simvastatin
Thaker_2021_Curr.Genet__Feruloyl esterase Fae1 is required specifically for host colonisation by the rice-blast fungus Magnaporthe oryzae
Thakkar_2021_Mol.Biol.Rep__Impact of chronic sub-lethal methylparaben exposure on cardiac hypoxia and alterations in neuroendocrine factors in zebrafish model
Thakur_2021_Med.Chem__Synthesis, Molecular Docking, BSA, and in-vitro reactivation study of imidazopyridine oxime against paraoxon inhibited acetylcholinesterase
Thandar_2021_J.UOEH_43_173Serum High-sensitivity C-reactive Protein Level and Corrected QT Interval in Agricultural Workers in Myanmar Exposed to Chronic Occupational Organophosphate Pesticides
Thapa_2021_Bioorg.Chem_108_104681Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer's disease
Thapak_2021_Neuromolecular.Med__Tranilast, a Transient Receptor Potential Vanilloid 2 Channel (TRPV2) Inhibitor Attenuates Amyloid beta-Induced Cognitive Impairment: Possible Mechanisms
Theilmann_2021_Epilepsia_62_269Hydrolytic biotransformation of the bumetanide ester prodrug DIMAEB to bumetanide by esterases in neonatal human and rat serum and neonatal rat brain-A new treatment strategy for neonatal seizures?
Thingore_2021_Metab.Brain.Dis_36_299Amelioration of oxidative stress and neuroinflammation in lipopolysaccharide-induced memory impairment using Rosmarinic acid in mice
Thoen_2021_Clin.Res.Hepatol.Gastroenterol_45_101638Low levels of Lysosomal Acid Lipase (LAL) activity increases necroinflammation in adult patients with biopsy-proven metabolic associated fatty liver disease
Thorne_2021_Mol.Imaging.Biol_23_127Imaging Butyrylcholinesterase in Multiple Sclerosis
Thornton_2021_Nat.Med_27_1666AlphaFold heralds a data-driven revolution in biology and medicine
Thors_2021_Cutan.Ocul.Toxicol__1Efficient agent degradation within skin is important for decontamination of percutaneously exposed VX
Thukham-Mee_2021_Oxid.Med.Cell.Longev_2021_5520059The Positive Modulation Effect of a 6-Week Consumption of an Anthocyanin-Rich Mulberry Milk on Working Memory, Cholinergic, and Monoaminergic Functions in Healthy Working-Age Adults
Tian_2021_Biotechnol.Biofuels_14_237Improved methanol tolerance of Rhizomucor miehei lipase based on Nglycosylation within the alpha-helix region and its application in biodiesel production
Tian_2021_Enzyme.Microb.Technol_150_109870Enhanced activity of Rhizomucor miehei lipase by directed saturation mutation of the propeptide
Tian_2021_J.Med.Chem__Triglyceride-Mimetic Structure-Gated Prodrug Nanoparticles for Smart Cancer Therapy
Tian_2021_J.Neurosci__Autism Spectrum Disorder/Intellectual Disability-associated mutations in Trio disrupt Neuroligin 1-mediated synaptogenesis
Tian_2021_Mini.Rev.Med.Chem__Multi-target drug design of anti-Alzheimer's disease based on tacrine
Tian_2021_Neurochem.Int_150_105197Soluble epoxide hydrolase inhibitor attenuates BBB disruption and neuroinflammation after intracerebral hemorrhage in mice
Tian_2021_Sheng.Wu.Gong.Cheng.Xue.Bao_37_88[Propeptide-mediated protein folding: mechanism and its impact on lipase]
Tigges_2021_Arch.Toxicol__Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense
Tiguman_2021_Rev.Paul.Pediatr_39_e2020130AVAILABILITY AND STORAGE OF HAZARDOUS PRODUCTS IN HOUSEHOLDS IN THE METROPOLITAN REGION OF MANAUS: A POPULATION-BASED SURVEY, 2015
Tinkov_2021_Mol.Inform_40_e2000209The Influence of Structural Patterns on Acute Aquatic Toxicity of Organic Compounds
Titov_2021_ACS.Chem.Neurosci__Away from Flatness: Unprecedented Nitrogen-Bridged Cyclopenta[a]indene Derivatives as Novel Anti-Alzheimer Multitarget Agents
Tiwari_2021_Sci.Rep_11_7042Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers
Tjora_2021_Eur.J.Gastroenterol.Hepatol_33_839Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis
Tkacz_2021_Food.Chem_338_128105Anti-diabetic, anti-cholinesterase, and antioxidant potential, chemical composition and sensory evaluation of novel sea buckthorn-based smoothies
Tlak_2021_Biology.(Basel)_10_Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157
To_2021_J.Clin.Med_10_Cognitive Dysfunction in a Mouse Model of Cerebral Ischemia Influences Salivary Metabolomics
Tobin_2021_BMC.Res.Notes_14_315Lipoprotein lipase hydrolysis products induce pro-inflammatory cytokine expression in triple-negative breast cancer cells
Todaka_2021_Eur.J.Pharmacol__174528Donepezil, an anti-Alzheimer's disease drug, promotes differentiation and regeneration in injured skeletal muscle through the elevation of the expression of myogenic regulatory factors
Tofiq_2021_J.Alzheimers.Dis__Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer's Disease: A Randomized Controlled Trial-The OmegAD Study
Tokali_2021_Arch.Pharm.(Weinheim)__e2000455Design, synthesis, molecular docking, and some metabolic enzyme inhibition properties of novel quinazolinone derivatives
Toldi_2021_Pancreatology__Missense PNLIP mutations impeding pancreatic lipase secretion cause protein misfolding and endoplasmic reticulum stress
Toledo-Ibarra_2021_Fish.Shellfish.Immunol_108_134Alterations in the non-neuronal cholinergic system induced by in-vitro exposure to diazoxon in spleen mononuclear cells of Nile tilapia (O. niloticus)
Tomou_2021_Nat.Prod.Res__1Polar constituents, biological effects and nutritional value of Sideritis sipylea Boiss
Tomovic_2021_J.Med.Chem__Structure-Activity Relationship Analysis of Cocrystallized Gliptin-like Pyrrolidine, Trifluorophenyl, and Pyrimidine-2,4-Dione Dipeptidyl Peptidase-4 Inhibitors
Tong_2021_Nat.Struct.Mol.Biol_28_771Could AlphaFold revolutionize chemical therapeutics?
Tong_2021_Pharmacol.Ther__107859Soluble ligands as drug targets for treatment of inflammatory bowel disease
Torabi_2021_Methods.Mol.Biol_2309_157Controlled Assays for Phenotyping the Effects of Strigolactone-Like Molecules on Arbuscular Mycorrhiza Development
Torres_2021_Gastrointest.Endosc__A rare case of lysosomal acid lipase deficiency diagnosed by endoscopy
Torres_2021_Neurosci__gCotreatment of small gold nanoparticles protects against the increase in cerebral acetylcholinesterase activity and oxidative stress induced by acute ethanol exposure in the zebrafish
Tortoriello_2021_Cannabis.Cannabinoid.Res_6_119Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB(1) Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster
Totsingan_2021_Molecules_26_Structure-Activity Relationship Assessment of Sophorolipid Ester Derivatives against Model Bacteria Strains
Toupenet_2021_Cells_10_Current Knowledge of Endolysosomal and Autophagy Defects in Hereditary Spastic Paraplegia
Traeger_2021_ANZ.J.Surg__The impact of acetylcholinesterase inhibitors on ileus and gut motility following abdominal surgery: a clinical review
Tran_2021_J.Med.Chem_64_17326Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors
Tran_2021_ScientificWorldJournal_2021_4817900Synthesis and Evaluation of the Acetylcholinesterase Inhibitory Activities of Some Flavonoids Derived from Naringenin
Treinin_2021_J.Neurochem_158_1274Cholinergic transmission in C. elegans: Functions, diversity, and maturation of ACh-activated ion channels
Trenaman_2021_BMC.Geriatr_21_297An examination of three prescribing cascades in a cohort of older adults with dementia
Triaca_2021_Adv.Exp.Med.Biol_1331_145NGF and the Amyloid Precursor Protein in Alzheimer's Disease: From Molecular Players to Neuronal Circuits
Tribuiani_2021_Curr.Mol.Med__Effects Of Doxycycline On Mice Neuromuscular Junction, In Situ
Trifan_2021_Plants.(Basel)_10_1825Influence of the Post-Harvest Storage Time on the Multi-Biological Potential, Phenolic and Pyrrolizidine Alkaloid Content of Comfrey (Symphytum officinale L.) Roots Collected from Different European Regions
Trifan_2021_Plants.(Basel)_10_2692Phytochemical Characterization and Evaluation of the Antioxidant and Anti-Enzymatic Activity of Five Common Spices: Focus on Their Essential Oils and Spent Material Extractives
Tripathi_2021_Drug.Dev.Res__Comprehensive investigations for a potential natural prophylaxis-A cellular and murine model for apple cider vinegar against hydrogen peroxide and scopolamine induced oxidative stress
Trobec_2021_Biomedicines_9_Fine Tuning of Cholinesterase and Glutathione-S-Transferase Activities by Organoruthenium(II) Complexes
Trotti_2021_Dement.Geriatr.Cogn.Dis.Extra_11_19Cerebrospinal Fluid Hypocretin and Nightmares in Dementia Syndromes
Tsagkaris_2021_Talanta_222_121535A microfluidic paper-based analytical device ( PAD) with smartphone readout for chlorpyrifos-oxon screening in human serum
Tsai_2021_Acta.Neurol.Taiwan_30(3)_118Treatable Rapid Progressive Dementia: A First Case Report of Anti-dipeptidyl-peptidase-like Protein 6 Encephalitis in Taiwan
Tsai_2021_Am.J.Hum.Genet__Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration
Tsai_2021_Curr.Opin.Toxicol_26_49Mechanisms of organophosphate neurotoxicity
Tschesche_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol__109095Genomic analysis of the carboxylesterase family in the salmon louse (Lepeophtheirus salmonis)
Tsetlin_2021_J.Neurochem_158_1223Three-finger proteins from snakes and humans acting on nicotinic receptors: Old and new
Tucker_2021_Front.Vet.Sci_8_685824Targeting Soluble Epoxide Hydrolase and Cyclooxygenases Enhance Joint Pain Control, Stimulate Collagen Synthesis, and Protect Chondrocytes From Cytokine-Induced Apoptosis
Tulsani_2021_Protein.Expr.Purif_187_105941Isolation, purification and characterization of a novel esterase from camel rumen metagenome
Tuncsoy_2021_Bull.Environ.Contam.Toxicol__Impacts of Titanium Dioxide Nanoparticles on Serum Parameters and Enzyme Activities of Clarias gariepinus
Tuncsoy_2021_Environ.Sci.Pollut.Res.Int__Influence of titanium dioxide nanoparticles on bioaccumulation, antioxidant defense and immune system of Galleria mellonella L
Tung_2021_RSC.Adv_11_31062Discovery of 8-prenylnaringenin from hop (Humulus lupulus L.) as a potent monoacylglycerol lipase inhibitor for treatments of neuroinflammation and Alzheimer's disease
Tunyasuvunakool_2021_Nature_596_590Highly accurate protein structure prediction for the human proteome
Turecky_2021_Bratisl.Lek.Listy_122_689Serum butyrylcholinesterase activities in patients with non-alcoholic fatty liver disease. Comparison with liver proteosynthetic function and liver fibrosis
Turecky_2021_Vnitr.Lek_67_4Serum butyrylcholinesterase/HDL-cholesterol ratio and atherogenic index of plasma in patients with fatty liver disease
Turkan_2021_J.Biomol.Struct.Dyn_39_3277Inhibition effects of isoproterenol, chlorpromazine, carbamazepine, tamoxifen drugs on Glutathione S- transferase, Cholinesterases enzymes and molecular docking studies
Turkan_2021_J.Biomol.Struct.Dyn_39_3693Determination of anticancer properties and inhibitory effects of some metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, alpha glycosidase of some compounds with molecular docking study
Turkes_2021_J.Biomol.Struct.Dyn__1Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and alpha-glucosidase inhibitors
Turkez_2021_Biomolecules_11_Glycyl-L-Prolyl-L-Glutamate Pseudotripeptides for Treatment of Alzheimer's Disease
Turkez_2021_Curr.Drug.Deliv__Therapeutic Potential of Ferulic Acid in Alzheimer's Disease
Turner_2021_Clin.Nutr_40_788Increased bioavailability of phenolic acids and enhanced vascular function following intake of feruloyl esterase-processed high fibre bread: A randomized, controlled, single blind, crossover human intervention trial
Tuzimski_2021_Molecules_26_Application of HPLC-DAD for In Vitro Investigation of Acetylcholinesterase Inhibition Activity of Selected Isoquinoline Alkaloids from Sanguinaria canadensis Extracts
Tyrrell_2021_J.Lipid.Res_62_100094Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions
Ucar_2021_Drug.Chem.Toxicol__1Neurotoxic responses of rainbow trout (Oncorhynchus mykiss) exposed to fipronil: multi-biomarker approach to illuminate the mechanism in brain
Uchigashima_2021_Front.Mol.Neurosci_14_749164Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction
Uckun_2021_Acta.Chim.Slov_68_521Acute Toxicity of Insecticide Thiamethoxam to Crayfish (Astacus leptodactylus): Alterations in Oxidative Stress Markers, ATPases and Cholinesterase
Uckun_2021_Environ.Sci.Pollut.Res.Int__Assessing the toxic effects of bisphenol A in consumed crayfish Astacus leptodactylus using multi biochemical markers
Uckun_2021_Environ.Toxicol.Chem__Evaluating Multiple Biochemical Markers in Xenopus laevis Tadpoles Exposed to the Pesticides Thiacloprid and Trifloxystrobin in Single and Mixed Forms
Uddin_2021_Evid.Based.Complement.Alternat.Med_2021_9995614Anticholinesterase Activity of Eight Medicinal Plant Species: In Vitro and In Silico Studies in the Search for Therapeutic Agents against Alzheimer's Disease
Uddin_2021_Mol.Neurobiol_58_281Multi-Target Drug Candidates for Multifactorial Alzheimer's Disease: AChE and NMDAR as Molecular Targets
Ueda_2021_Biosci.Biotechnol.Biochem__Cutinase-like biodegradable plastic-degrading enzymes from phylloplane yeasts have cutinase activity
Ueno_2021_Methods.Mol.Biol_2309_13Isolation and Identification of Naturally Occurring Strigolactones
Ul_2021_Molecules_26_Bio-Potency and Molecular Docking Studies of Isolated Compounds from Grewia optiva J.R. Drumm. ex Burret
Ullah_2021_Ecotoxicol.Environ.Saf_228_113032Heavy metals bioaccumulation and subsequent multiple biomarkers based appraisal of toxicity in the critically endangered Tor putitora
Ullah_2021_Int.Immunopharmacol_100_108083Attenuation of spatial memory in 5xFAD mice by targeting cholinesterases, oxidative stress and inflammatory signaling using 2-(hydroxyl-(2-nitrophenyl)methyl)cyclopentanone
Umar_2021_Braz.J.Biol_83_e248842Assessment of Cholinesterase inhibition activity of birds inhabiting pesticide exposed croplands and protected area in hot semi-arid region of Pakistan
Unbehend_2021_Nat.Commun_12_2818bric brac controls sex pheromone choice by male European corn borer moths
Undiano_2021_Food.Chem.Toxicol__112408Cu2+-dependent stereoselective hydrolysis of a chiral organophosphonothioate insecticide for domestic mammals' sera and its albumins
Uniyal_2021_Metab.Brain.Dis__Epigallocatechin-3-gallate improves chronic alcohol-induced cognitive dysfunction in rats by interfering with neuro-inflammatory, cell death and oxido-nitrosative cascade
Uno_2021_Biochem.Pharmacol_197_114887Drug-oxidizing and conjugating non-cytochrome P450 (non-P450) enzymes in cynomolgus monkeys and common marmosets as preclinical models for humans
Uras_2021_Front.Neurosci_15_691222In vivo Evaluation of a Newly Synthesized Acetylcholinesterase Inhibitor in a Transgenic Drosophila Model of Alzheimer's Disease
Urbanek_2021_Front.Bioeng.Biotechnol_9_771133Current Knowledge on Polyethylene Terephthalate Degradation by Genetically Modified Microorganisms
Urbanikova_2021_3.Biotech_11_84CE16 acetylesterases: in silico analysis, catalytic machinery prediction and comparison with related SGNH hydrolases
Usman_2021_Int.J.Environ.Res.Public.Health_18_Polystyrene Microplastics Exposure: An Insight into Multiple Organ Histological Alterations, Oxidative Stress and Neurotoxicity in Javanese Medaka Fish (Oryzias javanicus Bleeker, 1854)
Uta_2021_Mini.Rev.Med.Chem_21_1421Therapeutic Properties of Several Chemical Compounds of Salvia officinalis L. in Alzheimer's Disease
Valarezo_2021_Plants.(Basel)_10_Study of Volatile Secondary Metabolites Present in Piper carpunya Leaves and in the Traditional Ecuadorian Beverage Guaviduca
Valderrama_2021_J.Mol.Graph.Model_107_107951Finite-temperature effect in the O-acylation of (R,S)-propranolol catalyzed by Candida antarctica lipase B
Valdez_2021_Molecules_26_Analysis of Organophosphorus-Based Nerve Agent Degradation Products by Gas Chromatography-Mass Spectrometry (GC-MS): Current Derivatization Reactions in the Analytical Chemist's Toolbox
Valencia-Quintana_2021_Int.J.Environ.Res.Public.Health_18_Assessment of Cytogenetic Damage and Cholinesterases' Activity in Workers Occupationally Exposed to Pesticides in Zamora-Jacona, Michoacan, Mexico
Valente_2021_Eur.J.Pharm.Sci__105831Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma and liver hydrolysis
Valk_2021_Clin.Pharmacokinet__Etomidate and its Analogs: A Review of Pharmacokinetics and Pharmacodynamics
Valle-Martos_2021_Front.Pediatr_9_629346Liver Enzymes Correlate With Metabolic Syndrome, Inflammation, and Endothelial Dysfunction in Prepubertal Children With Obesity
Vallianatou_2021_ACS.Chem.Neurosci__Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain
Van Overloop_2021_Geriatr.Psychol.Neuropsychiatr.Vieil__Changes in psychotropic drug use among patients in the cognitive behavioural care unit in Toulon
Vanacek_2021_bioRxiv__Functional Annotation of an Enzyme Family by Integrated Strategy Combining Bioinformatics with Microanalytical and Microfluidic Technologies
Vanderriele_2021_Int.J.Mol.Sci_22_Salt-Sensitive Hypertension in GR(+/-) Rats Is Accompanied with Dysregulation in Adrenal Soluble Epoxide Hydrolase and Polyunsaturated Fatty Acid Pathways
Vanessa_2021_Mini.Rev.Med.Chem__Xanthone: Potential Acetylcholinesterase Inhibitor for Alzheimer's Disease Treatment
Vanova_2021_J.Pharm.Sci__Determination of K869, a novel oxime reactivator of acetylcholinesterase, in rat body fluids and tissues by liquid-chromatography methods: Pharmacokinetic study
Varma_2021_Biotechnol.J__e2100133Immobilization of transgenic plant cells towards bioprinting for production of a recombinant biodefense agent
Varshney_2021_CNS.Neurol.Disord.Drug.Targets__Role of natural plant products against Alzheimer's disease
Varshney_2021_Mol.Biol.Rep__Ang(1-7) exerts Nrf2-mediated neuroprotection against amyloid beta-induced cognitive deficits in rodents
Varshney_2021_Neuropeptides_86_102122Ang (1-7)/Mas receptor-axis activation promotes amyloid beta-induced altered mitochondrial bioenergetics in discrete brain regions of Alzheimer's disease-like rats
Vasamsetti_2021_Genes.(Basel)_12_Transcriptome-Based Identification of Genes Responding to the Organophosphate Pesticide Phosmet in Danio rerio
Vasilopoulou_2021_Br.J.Pharmacol__Disease-modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: A Comparative study with donepezil
Vasina_2021_ResearchSquare__Functional and Mechanistic Characterization of an Enzyme Family Combining Bioinformatics and High-Throughput Microfluidics
Vazquez-Alcantara_2021_Microbiol.Spectr_9_e0097621Expression of a Cutinase of Moniliophthora roreri with Polyester and PET-Plastic Residues Degradation Activity
Vecchio_2021_J.Cent.Nerv.Syst.Dis_13_11795735211029113The State of The Art on Acetylcholinesterase Inhibitors in the Treatment of Alzheimer's Disease
Veerabagu_2021_Front.Plant.Sci_12_674031Lipid Body Dynamics in Shoot Meristems: Production, Enlargement, and Putative Organellar Interactions and Plasmodesmal Targeting
Vergoossen_2021_Eur.J.Neurosci__Timing and localization of myasthenia gravis-related gene expression
Verma_2021_Biochimie__Current perspectives for microbial lipases from extremophiles and metagenomics
Verma_2021_Bioorg.Chem_119_105562The molecular mechanism, targets, and novel molecules in the treatment of Alzheimer's disease
Verma_2021_Curr.Mol.Pharmacol__A clinical perspective of soluble epoxide hydrolase inhibitors in metabolic and related cardiovascular diseases
Verma_2021_Drug.Metab.Lett__Ameliorative effect of Acetyl L-carnitine in Alzheimer's Disease via Downregulating of Homocysteine Levels in Hyperhomocysteinemia Induced Cognitive Deficit in mouse model
Viana_2021_Environ.Sci.Pollut.Res.Int__Bioconcentration and toxicological impacts of fipronil and 2,4-D commercial formulations (single and in mixture) in the tropical fish, Danio rerio
Viayna_2021_J.Med.Chem_64_812Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice
Vickstrom_2021_Mol.Psychiatry_26_3178Role of endocannabinoid signaling in a septohabenular pathway in the regulation of anxiety- and depressive-like behavior
Vieira_2021_Curr.Opin.Neurobiol_69_93The role of NMDA receptor and neuroligin rare variants in synaptic dysfunction underlying neurodevelopmental disorders
Vieira_2021_Ecotoxicol.Environ.Saf_211_111920Embryonic zebrafish response to a commercial formulation of azoxystrobin at environmental concentrations
Vieira_2021_Environ.Sci.Pollut.Res.Int__Cholinesterases of marine fish: characterization and sensitivity towards specific chemicals
Vieira_2021_Molecules_26_Microalgae as a Potential Functional Ingredient: Evaluation of the Phytochemical Profile, Antioxidant Activity and In-Vitro Enzymatic Inhibitory Effect of Different Species
Vieira_2021_Nat.Commun_12_4049Xyloglucan processing machinery in Xanthomonas pathogens and its role in the transcriptional activation of virulence factors
Vig_2021_J.Appl.Microbiol__Neuroprotective effects of quercetin produced by an endophytic fungus Nigrospora oryzae isolated from Tinospora cordifolia
Vignaux_2021_Chem.Res.Toxicol__The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase
Vilas_2021_Biotechnol.Bioeng__A review of synthesis of esters with aromatic, emulsifying, and lubricant properties by biotransformation using lipases
Vilela_2021_Front.Chem_9_708374Co-Immobilized Capillary Enzyme Reactor Based on Beta-Secretase1 and Acetylcholinesterase: A Model for Dual-Ligand Screening
Viljakainen_2021_Comput.Struct.Biotechnol.J_19_6191New approaches for the characterization of plastic-associated microbial communities and the discovery of plastic-degrading microorganisms and enzymes
Villaecija-Aguilar_2021_Curr.Biol__KAI2 promotes Arabidopsis root hair elongation at low external phosphate by controlling local accumulation of AUX1 and PIN2
Villaecija-Aguilar_2021_Methods.Mol.Biol_2309_129Bioassays for the Effects of Strigolactones and Other Small Molecules on Root and Root Hair Development
Villalta_2021_Plants.(Basel)_10_Selective BuChE Inhibitory Activity, Chemical Composition, and Enantiomeric Content of the Essential Oil from Salvia leucantha Cav. Collected in Ecuador
Vinces_2021_Biorxiv__Molecular and functional basis of a novel Amazonian Dark Earth Esterase 1 (Ade1) with hysteresis behavior and quorum-quenching activity
Vingiani_2021_Sci.Total.Environ_812_152535First identification and characterization of detoxifying plastic-degrading DBP hydrolases in the marine diatom Cylindrotheca closterium
Vinuela_2021_J.Alzheimers.Dis__Assessment of a Potential Synergistic Effect of Souvenaid in Mild Alzheimer's Disease Patients on Treatment with Acetylcholinesterase Inhibitors: An Observational, Non-Interventional Study
Virk_2021_Environ.Sci.Pollut.Res.Int__Ameliorative role of rolipram, PDE-4 inhibitor, against sodium arsenite-induced vascular dementia in rats
Virlogeux_2021_Sci.Adv_7_eabb0799Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice
Vitali_2021_Arterioscler.Thromb.Vasc.Biol_41_377Controversial Role of Lecithin:Cholesterol Acyltransferase in the Development of Atherosclerosis: New Insights From an LCAT Activator
Vitalo_2021_J.Vet.Emerg.Crit.Care.(San.Antonio)_31_106Therapeutic plasma exchange as adjunct therapy in 3 dogs with myasthenia gravis and myasthenia-like syndrome
Vogel_2021_Microorganisms_9_Comparative Genomics of Marine Bacteria from a Historically Defined Plastic Biodegradation Consortium with the Capacity to Biodegrade Polyhydroxyalkanoates
Vogel_2021_Sci.Total.Environ_773_145111Enzymatic degradation of polyethylene terephthalate nanoplastics analyzed in real time by isothermal titration calorimetry
Vohra_2021_Br.J.Clin.Pharmacol__Impact of deprivation, dementia prevalence and regional demography on prescribing of anti-dementia drugs in England: a time trend analysis
Vokuev_2021_Anal.Bioanal.Chem__Untargeted and targeted analysis of sarin poisoning biomarkers in rat urine by liquid chromatography and tandem mass spectrometry
Volkhina_2021_Klin.Lab.Diagn_66_389Prospects for the use of indicators of sialic acid metabolism in medicine (review of literature)
Vrabec_2021_Phytochemistry_194_113017Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease
Wade_2021_Front.Physiol_12_787535Lipid Transport in Brown Adipocyte Thermogenesis
Wagner_2021_Front.Pharmacol_12_778470Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation
Wagner_2021_J.Evol.Biol__Reconstruction of evolutionary changes in fat and toxin consumption reveals associations with gene losses in mammals: a case study for the lipase inhibitor PNLIPRP1 and the xenobiotic receptor NR1I3
Wakabayashi_2021_Planta_254_88Specific methylation of (11R)-carlactonoic acid by an Arabidopsis SABATH methyltransferase
Wakisaka_2021_Cerebrovasc.Dis__1Pre-Stroke Cholinesterase Inhibitor Treatment Is Beneficially Associated with Functional Outcome in Patients with Acute Ischemic Stroke and Pre-Stroke Dementia: The Fukuoka Stroke Registry
Walczak-Nowicka_2021_Int.J.Mol.Sci_22_Acetylcholinesterase Inhibitors in the Treatment of Neurodegenerative Diseases and the Role of Acetylcholinesterase in their Pathogenesis
Walia_2021_Future.Oncol__Genetic polymorphisms in the mEH gene in relation to tobacco smoking: role in lung cancer susceptibility and survival in north Indian patients with lung cancer undergoing platinum-based chemotherapy
Wall_2021_J.Med.Chem_64_10124Importance of Hydrogen Bonding: Structure-Activity Relationships of Ruthenium(III) Complexes with Pyridine-Based Ligands for Alzheimer's Disease Therapy
Wan_2021_ACS.Omega_6_23347Pd-Catalyzed Direct Modification of an Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of alpha-Aryl Donepezil Analogues
Wan_2021_ACS.Omega_6_9960Late-Stage Modification of Medicine: Pd-Catalyzed Direct Synthesis and Biological Evaluation of N-Aryltacrine Derivatives
Wang_2021_Acta.Crystallogr.D.Struct.Biol_77_1554Structural and biochemical analyses of the tetrameric carboxypeptidase S9Cfn from Fusobacterium nucleatum
Wang_2021_Am.J.Sports.Med__363546520988680The Enhancement Effect of Acetylcholine and Pyridostigmine on Bone-Tendon Interface Healing in a Murine Rotator Cuff Model
Wang_2021_Anal.Chem__Fabrication of Bioresource-Derived Porous Carbon-Supported Iron as an Efficient Oxidase Mimic for Dual-Channel Biosensing
Wang_2021_Angew.Chem.Int.Ed.Engl__Enzyme Control Over Ferric Iron Magnetostructural Properties
Wang_2021_Arch.Toxicol__Ensemble machine learning to evaluate the in vivo acute oral toxicity and in vitro human acetylcholinesterase inhibitory activity of organophosphates
Wang_2021_BMJ_374_n1925Use of antipsychotic drugs and cholinesterase inhibitors and risk of falls and fractures: self-controlled case series
Wang_2021_Biol.Pharm.Bull_44_9994D-QSAR Molecular Modeling and Analysis of Flavonoid Derivatives as Acetylcholinesterase Inhibitors
Wang_2021_Biomolecules_11_Micro-Aqueous Organic System: A Neglected Model in Computational Lipase Design?
Wang_2021_Bioorg.Chem_114_105148The chemical diversity, the attractant, anti-acetylcholinesterase, and antifungal activities of metabolites from biocontrol Trichoderma harzianum uncovered by OSMAC strategy
Wang_2021_Chem.Biol.Interact__109489Discovery of 7-O-1, 2, 3-triazole hesperetin derivatives as multi-target-directed ligands against Alzheimer's disease
Wang_2021_Chemosphere_275_129978Triphenyl phosphate disturbs the lipidome and induces endoplasmic reticulum stress and apoptosis in JEG-3 cells
Wang_2021_Clin.Chim.Acta__Two novel Mutations of the LPL Gene in two Chinese family cases with Familial Chylomicronemia Syndrome
Wang_2021_Clin.Transl.Sci__Impact of carboxylesterase 1 genetic polymorphism on trandolapril activation in human liver and the pharmacokinetics and pharmacodynamics in healthy volunteers
Wang_2021_Ecotoxicol.Environ.Saf_228_112959The cholinergic system, intelligence, and dental fluorosis in school-aged children with low-to-moderate fluoride exposure
Wang_2021_Ecotoxicol.Environ.Saf_230_113124Residual behaviors and metabolic pathway of ethylparaben in Drosophila melanogaster
Wang_2021_Environ.Pollut_284_117182Responses of Asian clams (Corbicula fluminea) to low concentration cadmium stress: Whether the depuration phase restores physiological characteristics
Wang_2021_Fitoterapia_156_105069Japonisine A, a fawcettimine-type Lycopodium alkaloid with an unusual skeleton from Lycopodium japonicum Thunb
Wang_2021_Foods_10_Perilla frutescens Leaf Extract and Fractions: Polyphenol Composition, Antioxidant, Enzymes (alpha-Glucosidase, Acetylcholinesterase, and Tyrosinase) Inhibitory, Anticancer, and Antidiabetic Activities
Wang_2021_Front.Chem_9_831173Secoyanhusamine A, an Oxidatively Ring-Opened Isoquinoline Inner Salt From Corydalis yanhusuo
Wang_2021_Front.Immunol_12_753247Antibodies to Full-Length Agrin Protein in Chinese Patients With Myasthenia Gravis
Wang_2021_Front.Oncol_11_791943Single-Nucleotide Polymorphisms Promote Dysregulation Activation by Essential Gene Mediated Bio-Molecular Interaction in Breast Cancer
Wang_2021_Front.Pharmacol_12_615104Ultrasound Combined With Microbubbles Loading BDNF Retrovirus to Open BloodBrain Barrier for Treatment of Alzheimer's Disease
Wang_2021_Front.Plant.Sci_12_664470Genome-Wide Identification of Tannase Genes and Their Function of Wound Response and Astringent Substances Accumulation in Juglandaceae
Wang_2021_Front.Psychiatry_12_638328Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats
Wang_2021_Genome.Med_13_83An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
Wang_2021_Insect.Sci__Influence of seasonal migration on evolution of insecticide resistance in Plutella xylostella
Wang_2021_Int.J.Mol.Med_48_Perspective on prenatal polychlorinated biphenyl exposure and the development of the progeny nervous system (Review)
Wang_2021_Int.J.Mol.Sci_22_13366Systematic Analysis and Biochemical Characterization of the Caffeoyl Shikimate Esterase Gene Family in Poplar
Wang_2021_Int.J.Mol.Sci_22_1387Identification, Classification, and Expression Analysis of the Triacylglycerol Lipase (TGL) Gene Family Related to Abiotic Stresses in Tomato
Wang_2021_J.Affect.Disord_292_565Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve
Wang_2021_J.Agric.Food.Chem_69_6665Rational Design for Broadened Substrate Specificity and Enhanced Activity of a Novel Acetyl Xylan Esterase from Bacteroides thetaiotaomicron
Wang_2021_J.Agric.Food.Chem__Discovery of a Broad-Spectrum Fluorogenic Agonist for Strigolactone Receptors through a Computational Approach
Wang_2021_J.Anal.Toxicol__Transesterification of Indazole-3-Carboxamide Synthetic Cannabinoids: Identification of Metabolite Biomarker for Diagnosing Co-Abuse of 5F-MDMB-PINACA and Alcohol
Wang_2021_J.Biotechnol_335_47Conjugation of haloalkane dehalogenase DhaA with arabinogalactan to increase its stability
Wang_2021_J.Environ.Sci.Health.B__1Plasma cholinesterase activity is influenced by interactive effect between omethoate exposure and CYP2E1 polymorphisms
Wang_2021_J.Food.Biochem__e13618Protective effects of orally administered shark compound peptides from Chiloscyllium plagiosum against acute inflammation
Wang_2021_J.Hazard.Mater_403_123921Preparation and properties of a dual-function cellulose nanofiber-based bionic biosensor for detecting silver ions and acetylcholinesterase
Wang_2021_J.Nanobiotechnology_19_31Protein liposomes-mediated targeted acetylcholinesterase gene delivery for effective liver cancer therapy
Wang_2021_J.Obstet.Gynaecol.Res__Inhibition of monoacylglycerol lipase restrains proliferation, migration, invasion, tumor growth and induces apoptosis in cervical cancer
Wang_2021_J.Pain.Res_14_61Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence
Wang_2021_J.Sep.Sci__Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays
Wang_2021_Molecules_26_An Evolving Technology That Integrates Classical Methods with Continuous Technological Developments: Thin-Layer Chromatography Bioautography
Wang_2021_Neurosci.Bull__TRPV4 Regulates Soman-Induced Status Epilepticus and Secondary Brain Injury via NMDA Receptor and NLRP3 Inflammasome
Wang_2021_Pest.Manag.Sci_77_2114Resistance of Bemisia tabaci Mediterranean (Q-biotype) to pymetrozine: resistance risk assessment, cross-resistance to six other insecticides and detoxification enzyme assay
Wang_2021_Pest.Manag.Sci__Two carboxylesterase genes in Plutella xylostella associated with sex pheromones and plant volatiles degradation
Wang_2021_Pest.Manag.Sci__2Neuroligin 3 from common cutworm enhances the Gaba-induced current of recombinant Slrdl1 channel
Wang_2021_Pharmaceutics_13_Metabolism and Interspecies Variation of IMMH-010, a Programmed Cell Death Ligand 1 Inhibitor Prodrug
Wang_2021_Plant.Physiol_185_1411Molecular basis for high ligand sensitivity and selectivity of strigolactone receptors in Striga
Wang_2021_Planta.Med__Berberine Ameliorates Glucose Metabolism in Diabetic Rats through the alpha7 Nicotinic Acetylcholine Receptor-Related Cholinergic Anti-Inflammatory Pathway
Wang_2021_Proteins__The protonation state of Glu202 in acetylcholinesterase
Wang_2021_Sci.Total.Environ__152751Carboxylesterases from bacterial enrichment culture degrade strobilurin fungicides
Wang_2021_Theranostics_11_8535Neuronal-driven glioma growth requires Galphai1 and Galphai3
Wang_2021_Toxicology__152725Decrease of an intracellular organic osmolyte contributes to the cytotoxicity of organophosphate in neuroblastoma cells in vitro
Wang_2021_Trends.Plant.Sci__Origins of strigolactone and karrikin signaling in plants
Wang_2021_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_39_147[A case of death caused by fenitrothion poisoning]
Wang_2021_Zhonghua.Nei.Ke.Za.Zhi_60_134[Serum C-reactive protein, cholinesterase and prealbumin are correlated with prognosis of severe coronavirus disease 2019 patients]
Wannasaksri_2021_Molecules_26_In Vitro Phytotherapeutic Properties of Aqueous Extracted Adenia viridiflora Craib. towards Civilization Diseases
Waseem_2021_ACS.Omega_6_7910Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer's Disease
Watt_2021_BMC.Med.Res.Methodol_21_41Using a distribution-based approach and systematic review methods to derive minimum clinically important differences
Watt_2021_BMJ_372_n532Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis
Watts_2021_Future.Cardiol__Transcriptomic therapy for dyslipidemias utilizing nucleic acids targeted at ANGPTL3
Weber_2021_Eur.J.Gastroenterol.Hepatol__Novel predictors for liver transplantation or death in drug-induced acute liver failure
Wedn_2021_Biochem.Pharmacol_192_114703Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: Therapeutic perspectives
Wei_2021_ACS.Appl.Mater.Interfaces__A Lab-in-a-Syringe Device Integrated with a Smartphone Platform: Colorimetric and Fluorescent Dual-Mode Signals for On-Site Detection of Organophosphorus Pesticides
Wei_2021_Appl.Microbiol.Biotechnol__Metabolic engineering Yarrowia lipolytica for a dual biocatalytic system to produce fatty acid ethyl esters from renewable feedstock in situ and in one pot
Wei_2021_Chemosphere_270_128647Odorant degrading carboxylesterases modulate foraging and mating behaviors of Grapholita molesta
Wei_2021_Eur.J.Med.Chem_215_113286Molecular modeling-guided optimization of acetylcholinesterase reactivators: A proof for reactivation of covalently inhibited targets
Wei_2021_Fitoterapia__105090Structurally diverse Monascus pigments with hypolipidemic and hepatoprotective activities from highland barley Monascus
Wei_2021_J.Agric.Food.Chem__The alpha-Helical Cap Domain of a Novel Esterase from Gut Alistipes shahii Shaping the Substrate-Binding Pocket
Wei_2021_Pestic.Biochem.Physiol_175_104857Novel amide derivatives containing an imidazo[1,2-a]pyridine moiety: Design, synthesis as potential nematicidal and antibacterial agents
Wei_2021_Phytochemistry_190_112867Euphorfinoids E-L: Diterpenoids from the roots of Euphorbia fischeriana with acetylcholinesterase inhibitory activity
Weigert_2021_Protein.Eng.Des.Sel_34_A versatile assay platform for enzymatic poly(ethylene-terephthalate) degradation
Wen_2021_Enzyme.Microb.Technol_146_109778Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide
Weng_2021_Biomed.Pharmacother_141_111865Syringaldehyde promoting intestinal motility with suppressing alpha-amylase hinders starch digestion in diabetic mice
Wenzel_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1180_122891Mass spectrometry-based targeted proteomics method for the quantification of clinically relevant drug metabolizing enzymes in human specimens
Werner_2021_Metab.Eng_67_250Tandem chemical deconstruction and biological upcycling of poly(ethylene terephthalate) to beta-ketoadipic acid by Pseudomonas putida KT2440
Wessinger_2021_Int.J.Exerc.Sci_14_727Effect of Huperzine A on Cognitive Function and Perception of Effort during Exercise: A Randomized Double-Blind Crossover Trial
Whitfield_2021_Twin.Res.Hum.Genet__1Comparison of Familial, Polygenic and Biochemical Predictors of Mortality
Wichur_2021_Eur.J.Med.Chem_225_113783Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT(6) receptor with anti-aggregation properties against amyloid-beta and tau
Wichur_2021_Eur.J.Med.Chem_225_113792Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT6R antagonists with beta-amyloid anti-aggregation properties
Wiegmann_2021_Int.J.Parasitol.Parasites.Wildl_16_236The prevalence of Leucocytozoon spp. in nestlings of three wild raptor species including implications on haematological and blood chemistry values
Wigenstam_2021_Toxicol.Appl.Pharmacol__115512Efficacy of atropine and scopolamine on airway contractions following exposure to the nerve agent VX
Wiley_2021_Front.Physiol_12_699712UPLC-MS/MS Method for Analysis of Endocannabinoid and Related Lipid Metabolism in Mouse Mucosal Tissue
Wilhelm_2021_Biochemistry_60_2560Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag
Wilkerson_2021_Pharmacol.Biochem.Behav__173192Untapped endocannabinoid pharmacological targets: pipe dream or pipeline?
Wilt_2021_Bioorg.Med.Chem_51_116507Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors
Winek_2021_J.Neurochem__Regulators of cholinergic signaling in disorders of the central nervous system
Witeck_2021_J.Pediatr.(Rio.J)__Lysosomal acid lipase deficiency in pediatric patients: A scoping review
Wojdylo_2021_Antioxidants.(Basel)_10_Profile of Phenolic Compounds of Prunus armeniaca L. Leaf Extract Determined by LC-ESI-QTOF-MS/MS and Their Antioxidant, Anti-Diabetic, Anti-Cholinesterase, and Anti-Inflammatory Potency
Wojdylo_2021_Sci.Rep_11_20253Comparison of bioactive compounds and health promoting properties of fruits and leaves of apple, pear and quince
Wolie_2021_Parasit.Vectors_14_581Evaluation of the interaction between insecticide resistance-associated genes and malaria transmission in Anopheles gambiae sensu lato in central Cte d'Ivoire
Wong_2021_Diabetes.Metab__101307Use of DPP4i reduced odds of clinical deterioration and hyperinflammatory syndrome in COVID-19 patients with type 2 diabetes: propensity score analysis of a territory-wide cohort in Hong Kong
Wong_2021_Neuropsychopharmacology__Autistic-like behavior, spontaneous seizures, and increased neuronal excitability in a Scn8a mouse model
Wopara_2021_Heliyon_7_e06378Anxiogenic and memory impairment effect of food color exposure: upregulation of oxido-neuroinflammatory markers and acetyl-cholinestrase activity in the prefrontal cortex and hippocampus
Wopara_2021_Heliyon_7_e08454Involvement of striatal oxido-inflammatory, nitrosative and decreased cholinergic activity in neurobehavioral alteration in adult rat model with oral co-exposure to erythrosine and tartrazine
Wrobel_2021_J.Am.Chem.Soc__Combinatorial Assembly of Modular Glucosides via Carboxylesterases Regulates C. elegans Starvation Survival
Wu_2021_Anal.Chem__Two-Dimensional MnO(2) Nanozyme-Mediated Homogeneous Electrochemical Detection of Organophosphate Pesticides without the Interference of H(2)O(2) and Color
Wu_2021_Angew.Chem.Int.Ed.Engl__Rational Design of Highly Selective Near-Infrared Two-Photon Fluorogenic Probe for Imaging Orthotopic Hepatocellular Carcinoma Chemotherapy
Wu_2021_BMC.Pediatr_21_414Rare novel LPL mutations are associated with neonatal onset lipoprotein lipase (LPL) deficiency in two cases
Wu_2021_Bioorg.Med.Chem.Lett__128316Design, synthesis and biological evaluation of naringenin carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease
Wu_2021_Clin.Transl.Med_11_e428Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum-hippocampus cholinergic pathway
Wu_2021_Eur.J.Neurosci__Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice
Wu_2021_Food.Chem_359_129960Binding mechanism and functional evaluation of quercetin 3-rhamnoside on lipase
Wu_2021_Front.Plant.Sci_12_793459A Unique Sulfotransferase-Involving Strigolactone Biosynthetic Route in Sorghum
Wu_2021_Insects_12_Exposure of Helicoverpa armigera Larvae to Plant Volatile Organic Compounds Induces Cytochrome P450 Monooxygenases and Enhances Larval Tolerance to the Insecticide Methomyl
Wu_2021_J.Enzyme.Inhib.Med.Chem_36_1860Structure-activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease
Wu_2021_J.Fungi.(Basel)_7_Synergistic Interaction between the Entomopathogenic Fungus Akanthomyces attenuatus (Zare & Gams) and the Botanical Insecticide Matrine against Megalurothrips usitatus (Bagrall)
Wu_2021_J.Sep.Sci__Absolute protein assay for the simultaneous quantification of two epoxide hydrolases in rats by mass spectrometry-based targeted proteomics
Wu_2021_Medicine.(Baltimore)_100_e26654Case Report/Case Series: Rare case of anti-LGI1 limbic encephalitis with rapidly progressive dementia, psychiatric symptoms, and frequently seizures: A case report
Wu_2021_Org.Lett__Millmerranones A-F: A Meroterpene Cyclic Carbonate and Related Metabolites from the Australian Fungus Aspergillus sp. CMB-MRF324
Wu_2021_Plant.Physiol_187_681TIR signal promotes interactions between lipase-like proteins and ADR1-L1 receptor and ADR1-L1 oligomerization
Wu_2021_Sci.Total.Environ__152285Biological responses of Eisenia fetida towards the exposure and metabolism of tris (2-butoxyethyl) phosphate
Wu_2021_Trends.Endocrinol.Metab_32_48Lipoprotein Lipase and Its Regulators: An Unfolding Story
Wullich_2021_Chembiochem_22_733Stabilizing AqdC, a Pseudomonas Quinolone Signal-Cleaving Dioxygenase from Mycobacteria, by FRESCO-Based Protein Engineering
Wurlitzer_2021_Appl.Environ.Microbiol_87_e02051Bacterial-Like Nonribosomal Peptide Synthetases Produce Cyclopeptides in the Zygomycetous Fungus Mortierella alpina
Xi_2021_Enzyme.Microb.Technol_143_109715Secretory expression in Bacillus subtilis and biochemical characterization of a highly thermostable polyethylene terephthalate hydrolase from bacterium HR29
Xia_2021_Anal.Sci_37_1023Peroxidase-mimicking Activity of PCN-222(Fe) for Colorimetric Sensing of Acetylcholinesterase Activity and Inhibition
Xia_2021_Ecotoxicol.Environ.Saf_218_112308Developmental neurotoxicity of antimony (Sb) in the early life stages of zebrafish
Xia_2021_Proc.Natl.Acad.Sci.U.S.A_118_Imaging in vivo acetylcholine release in the peripheral nervous system with a fluorescent nanosensor
Xiang_2021_Foods_10_UPLC-MS/MS Profiling, Antioxidant, alpha-Glucosidase Inhibitory, Cholinesterase Inhibitory, and Cardiovascular Protection Potentials of Jialing 20 (Morus multicaulis Perr.) Mulberry Branch Extract
Xiao_2021_Biomed.Res.Int_2021_5574207Celastrol Attenuates Learning and Memory Deficits in an Alzheimer's Disease Rat Model
Xiao_2021_Biotechnol.Lett__An uncharacterized protein from the metagenome with no obvious homology to known lipases shows excellent alkaline lipase properties and potential applications in the detergent industry
Xiao_2021_Langmuir__Enzyme-Responsive Aqueous Two-Phase Systems in a Cationic-Anionic Surfactant Mixture
Xiao_2021_Talanta_221_121362A thiamine-triggered fluormetric assay for acetylcholinesterase activity and inhibitor screening based on oxidase-like activity of MnO(2) nanosheets
Xie_2021_Bioorg.Chem_109_104710Synthesis and biological evaluation of novel 8- substituted sampangine derivatives as potent inhibitor of Zn(2+)-Abeta complex mediated toxicity, oxidative stress and inflammation
Xie_2021_Cell.Death.Dis_12_1003Cardiac-specific CGI-58 deficiency activates the ER stress pathway to promote heart failure in mice
Xie_2021_J.Neurochem_158_1254New perspective on the regulation of acetylcholinesterase via the aryl hydrocarbon receptor
Xie_2021_Methods.Mol.Biol_2309_3Evaluation and Quantification of Natural Strigolactones from Root Exudates
Xin_2021_Arch.Insect.Biochem.Physiol__e21850Construction and analysis of the protein-protein interaction network for the detoxification enzymes of the silkworm, Bombyx mori
Xin_2021_Int.J.Mol.Sci_22_Catalytic Descriptors to Investigate Catalytic Power in the Reaction of Haloalkane Dehalogenase Enzyme with 1,2-Dichloroethane
Xing_2021_Enzyme.Microb.Technol_149_109849Enhancing the thermostability of a mono- and diacylglycerol lipase from Malassizia globose by stabilizing a flexible loop in the catalytic pocket
Xing_2021_Front.Microbiol_12_633489Gene Expression, Biochemical Characterization of a sn-1, 3 Extracellular Lipase From Aspergillus niger GZUF36 and Its Model-Structure Analysis
Xing_2021_Int.J.Biol.Macromol_166_1352Synthesis and bio-evaluation of a novel selective butyrylcholinesterase inhibitor discovered through structure-based virtual screening
Xing_2021_Med.Res.Rev_41_858Structure and therapeutic uses of butyrylcholinesterase: Application in detoxification, Alzheimer's disease, and fat metabolism
Xiong_2021_Bioorg.Med.Chem.Lett__127986Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening
Xiong_2021_Brain.Sci_11_Understanding the Modulatory Effects of Cannabidiol on Alzheimer's Disease
Xiong_2021_Nutrition_86_111155Vitamins A and D fail to protect against tuberculosis-drug-induced liver injury: A post hoc analysis of a previous randomized controlled trial
Xu_2021_3.Biotech_11_370Bioinformatics analysis of PAE family in Populus trichocarpa and responsiveness to carbon and nitrogen treatment
Xu_2021_Anal.Chem__Construction of Peroxidase-like Metal-Organic Frameworks in TiO(2) Nanochannels: Robust Free-Standing Membranes for Diverse Target Sensing
Xu_2021_BMC.Genomics_22_350Genome-wide analysis of the serine carboxypeptidase-like protein family in Triticum aestivum reveals TaSCPL184-6D is involved in abiotic stress response
Xu_2021_Case.Rep.Gastrointest.Med_2021_9948854The Effect of the Platelet Administration for the Patients with Liver Dysfunction after Liver Resection: Preliminary Clinical Trial
Xu_2021_Environ.Pollut_273_116461An efficient phthalate ester-degrading Bacillus subtilis: Degradation kinetics, metabolic pathway, and catalytic mechanism of the key enzyme
Xu_2021_Food.Chem_372_131256An efficient and robust continuous-flow bioreactor for the enzymatic preparation of phytosterol esters based on hollow lipase microarray
Xu_2021_J.Agric.Food.Chem_69_11554Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
Xu_2021_J.Agric.Food.Chem_69_13102Efficient Enzymatic Synthesis of Lipophilic Phenolic Glycoside Azelaic Acid Esters and Their Depigmenting Activity
Xu_2021_J.Exp.Bot__Strigolactones regulate sepal senescence in Arabidopsis
Xu_2021_Microb.Cell.Fact_20_152The N-terminus of Lactobacillus amylovorus feruloyl esterase plays an important role in its secretion by Lactobacillus plantarum and Escherichia coli
Xu_2021_Nat.Chem__Catalytic reductive desymmetrization of malonic esters
Xu_2021_Nat.Plants_7_1495Catabolism of strigolactones by a carboxylesterase
Xu_2021_Neurology_97_965Author Response: Long-term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Xu_2021_Neurology__Long Term Effects of Cholinesterase Inhibitors on Cognitive Decline and Mortality
Xu_2021_Pestic.Biochem.Physiol_179_104969Two single mutations in carboxylesterase 001C improve fenvalerate hydrolase activity in Helicoverpa armigera
Xu_2021_Sci.Rep_11_9450PbCSE1 promotes lignification during stone cell development in pear (Pyrus bretschneideri) fruit
Xuan_2021_ACS.Chem.Neurosci_12_2462Dimeric Tacrine(10)-hupyridone as a Multitarget-Directed Ligand To Treat Alzheimer's Disease
Xue_2021_CNS.Neurosci.Ther__Identification of a large homozygous SPG21 deletion in a Chinese patient with Mast syndrome
Xue_2021_Front.Bioeng.Biotechnol_9_762854Fusion of Chitin-Binding Domain From Chitinolyticbacter meiyuanensis SYBC-H1 to the Leaf-Branch Compost Cutinase for Enhanced PET Hydrolysis
Xue_2021_J.Biomol.Struct.Dyn__1Using structural analysis to clarify the impact of single nucleotide variants in neurexin/neuroligin revealed in clinical genomic sequencing
Xue_2021_J.Cell.Physiol_236_2649m(6) A transferase METTL3-induced lncRNA ABHD11-AS1 promotes the Warburg effect of non-small-cell lung cancer
Xue_2021_Theor.Appl.Genet__A methyl esterase 1 (PvMES1) promotes the salicylic acid pathway and enhances Fusarium wilt resistance in common beans
Yadav_2021_Clin.Chim.Acta_520_34Acute aluminum phosphide poisoning: The menace of phosphine exposure
Yadav_2021_Environ.Toxicol_36_572Biofabricated zinc oxide nanoparticles impair cognitive function via modulating oxidative stress and acetylcholinesterase level in mice
Yagishita-Kyo_2021_Biochem.Biophys.Res.Commun_551_54Testosterone interrupts binding of Neurexin and Neuroligin that are expressed in a highly socialized rodent, Octodon degus
Yahia_2021_Front.Neurol_12_720201Pathogenic Variants in ABHD16A Cause a Novel Psychomotor Developmental Disorder With Spastic Paraplegia
Yainna_2021_Insects_12_Geographic Monitoring of Insecticide Resistance Mutations in Native and Invasive Populations of the Fall Armyworm
Yamaga_2021_Nutrients_13_Acetylcholine and Royal Jelly Fatty Acid Combinations as Potential Dry Eye Treatment Components in Mice
Yamaguchi_2021_ACS.Appl.Bio.Mater_4_6512Paper-Based Analytical Device for the On-Site Detection of Nerve Agents
Yamamoto_2021_Plant.Signal.Behav__1961062Identification and molecular characterization of propionylcholinesterase, a novel pseudocholinesterase in rice
Yamasaki_2021_Intern.Med__Two Lambert-Eaton Myasthenic Syndrome Patients with Ameliorated Activities of Daily Living Due to Cholinesterase Inhibitors
Yamasaki_2021_Theranostics_11_9492Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study
Yamashita_2021_Mol.Ther.Methods.Clin.Dev_22_263Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research
Yamazaki_2021_Bioorg.Med.Chem_32_115991Novel arylcarbamate-N-acylhydrazones derivatives as promising BuChE inhibitors: Design, synthesis, molecular modeling and biological evaluation
Yan_2021_Anim.Dis_1_15The nucleoside antiviral prodrug remdesivir in treating COVID-19 and beyond with interspecies significance
Yan_2021_Appl.Microbiol.Biotechnol__Synergistic biodegradation of poly(ethylene terephthalate) using Microbacterium oleivorans and Thermobifida fusca cutinase
Yan_2021_Arch.Microbiol__Identification and characterization of a novel carboxylesterase EstQ7 from a soil metagenomic library
Yan_2021_Cell.Mol.Life.Sci__Silencing the triacylglycerol lipase (TGL) gene decreases the number of apyrene sperm and inhibits oviposition in Sitotroga cerealella
Yan_2021_Environ.Sci.Technol__Comprehensive Interrogation on Acetylcholinesterase Inhibition by Ionic Liquids Using Machine Learning and Molecular Modeling
Yan_2021_Genome.Biol.Evol__A highly contiguous genome assembly of a polyphagous predatory mite Stratiolaelaps scimitus (Womersley) (Acari: Laelapidae)
Yan_2021_Mikrochim.Acta_188_162Colorimetric detection of acetylcholinesterase and its inhibitor based on thiol-regulated oxidase-like activity of 2D palladium square nanoplates on reduced graphene oxide
Yan_2021_Sci.Total.Environ_785_147260Characterization of a novel carboxylesterase with catalytic activity toward di(2-ethylhexyl) phthalate from a soil metagenomic library
Yang_2021_Ann.Palliat.Med_10_11714Cholinesterase level is a predictor of systemic inflammatory response syndrome and complications after cardiopulmonary bypass
Yang_2021_Arch.Oral.Biol_130_105211Notum suppresses the osteogenic differentiation of periodontal ligament stem cells through the Wnt/Beta catenin signaling pathway
Yang_2021_Arch.Toxicol__Thifluzamide exposure induced neuro-endocrine disrupting effects in zebrafish (Danio rerio)
Yang_2021_Bioorg.Med.Chem_37_116109Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia
Yang_2021_Cardiovasc.Drugs.Ther_35_467Research Progress on the Involvement of ANGPTL4 and Loss-of-Function Variants in Lipid Metabolism and Coronary Heart Disease: Is the Prime Time of ANGPTL4-Targeted Therapy for Coronary Heart Disease Approaching?
Yang_2021_Cell.J_23_355Neuroprotective Effects of Isoquercetin: An In Vitro and In Vivo Study
Yang_2021_Cell.Mol.Biol.Lett_26_50Esterase D stabilizes FKBP25 to suppress mTORC1
Yang_2021_Chemosphere_275_129974Influence of suspended sediment on the bioavailability of benzophenone-3: Focus on accumulation and multi-biological effects in Daphnia magna
Yang_2021_Clin.Neuropharmacol__Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis With Peripheral Nerve Hyperexcitability: Case Report and Literature Review
Yang_2021_Comp.Biochem.Physiol.C.Toxicol.Pharmacol_253_109248Neurotoxicity induced by combined exposure of microcystin-LR and nitrite in male zebrafish (Danio rerio): Effects of oxidant-antioxidant system and neurotransmitter system
Yang_2021_Ecotoxicol.Environ.Saf_208_111700Molecular and behavioral responses of zebrafish embryos/larvae after sertraline exposure
Yang_2021_Eur.J.Pharmacol__173950A review on alpha-mangostin as a potential multi-target-directed ligand for Alzheimer's disease
Yang_2021_Exp.Ther.Med_22_1252Evidence-based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease
Yang_2021_Fitoterapia_153_104948A norbisabolane and an arabitol benzoate from Talaromyces marneffei, an endophytic fungus of Epilobium angustifolium
Yang_2021_Food.Chem_376_131906Ultrasmall Au nanoparticles modified 2D metalloporphyrinic metal-organic framework nanosheets with high peroxidase-like activity for colorimetric detection of organophosphorus pesticides
Yang_2021_Front.Pharmacol_12_647481Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice
Yang_2021_Int.J.Mol.Sci_22_Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice
Yang_2021_J.Agric.Food.Chem__pH-Response Quantum Dots with Orange-Red Emission for Monitoring the Residue, Distribution, and Variation of an Organophosphorus Pesticide in an Agricultural Crop
Yang_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1170_122599Rapid screening for natural lipase inhibitors from Alisma orientale combining high-performance thin-layer chromatography-bioautography with mass spectrometry
Yang_2021_J.Obstet.Gynaecol.Res__Dipeptidyl peptidase IV is required for endometrial carcinoma cell proliferation and tumorigenesis via the IL-6/STAT3 pathway
Yang_2021_Mar.Drugs_19_An In-Silico Comparative Study of Lipases from the Antarctic Psychrophilic Ciliate Euplotes focardii and the Mesophilic Congeneric Species Euplotes crassus: Insight into Molecular Cold-Adaptation
Yang_2021_Med.Sci.Monit_27_e928523Identification of NDRG Family Member 4 (NDRG4) and CDC28 Protein Kinase Regulatory Subunit 2 (CKS2) as Key Prognostic Genes in Adrenocortical Carcinoma by Transcriptomic Analysis
Yang_2021_Nanotechnology__A highly sensitive acetylcholinesterase electrochemical biosensor based on Au-Tb alloy nanospheres for determining organophosphate pesticides
Yang_2021_Nat.Prod.Res__1Stephtetrandrine A-D, bisbenzylisoquinoline alkaloids from Stephania tetrandra
Yang_2021_Pest.Manag.Sci_77_3685Bioactivities and modes of action of VUAA1
Yang_2021_Plant.Cell__Misregulation of MYB16 expression causes stomatal cluster formation by disrupting polarity during asymmetric cell divisions
Yang_2021_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_262_120094Ultrasensitive fluorescent probe for visual biosensing of esterase activity in living cells and its imaging application
Yanxian_2021_Toxicology__152934Toxic effects of subacute exposure to acrylamide on motor endplates of the gastrocnemius in rats
Yao_2021_AMB.Express_11_38A novel esterase from a soil metagenomic library displaying a broad substrate range
Yao_2021_Czech.J.Genet.Plant.Breed__Isolation, sequencing of the HvnHID gene and its role in the purple-grain colour development in Tibetan hulless barley
Yao_2021_Front.Microbiol_12_743377A Valuable Product of Microbial Cell Factories: Microbial Lipase
Yao_2021_J.Med.Chem__Discovery of Novel Tacrine-Pyrimidone Hybrids as Potent Dual AChE/GSK-3 Inhibitors for the Treatment of Alzheimer's Disease
Yao_2021_New.Phytol__Desmethyl butenolides are optimal ligands for karrikin receptor proteins
Yasin_2021_Arch.Microbiol_203_1309Alkaline lipase production by novel meso-tolerant psychrophilic Exiguobacterium sp. strain (AMBL-20) isolated from glacier of northeastern Pakistan
Yasuda_2021_Drug.Metab.Pharmacokinet_39_100397Epicatechin gallate and epigallocatechin gallate are potent inhibitors of human arylacetamide deacetylase
Yasuno_2021_Int.J.Geriatr.Psychiatry__Significant effects of cholinesterase inhibitors on tau pathology in the Alzheimer's disease continuum: An in vivo positron emission tomography study
Yasutake_2021_Int.J.Biol.Macromol_167_578Bacterial triacylglycerol lipase is a potential cholesterol esterase: Identification of a key determinant for sterol-binding specificity
Yavari_2021_J.Biochem.Mol.Toxicol__e22952Synthesis and some enzyme inhibition effects of isoxazoline and pyrazoline derivatives including benzonorbornene unit
Yavasoglu_2021_Pestic.Biochem.Physiol_171_104746The first implementation of allele-specific primers for detecting the knockdown and acetylcholinesterase target site mutations in malaria vector, Anopheles sacharovi
Ye_2021_Bioorg.Chem_111_104895Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents
Ye_2021_PeerJ_9_e10919Putative carboxylesterase gene identification and their expression patterns in Hyphantria cunea (Drury)
Ye_2021_Trop.Anim.Health.Prod_53_366Association analysis between FASN genotype and milk traits in Mediterranean buffalo and its expression among different buffalo tissues
Yeh_2021_Life.Sci_278_119574DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity
Yi_2021_Appl.Microbiol.Biotechnol_105_7757Characterization and structural analysis of a thermophilic GH11 xylanase from compost metatranscriptome
Yi_2021_Front.Physiol_12_674023Identification of Candidate Carboxylesterases Associated With Odorant Degradation in Holotrichia parallela Antennae Based on Transcriptome Analysis
Yigit_2021_Bioorg.Chem_120_105566Selenourea and thiourea derivatives of chiral and achiral enetetramines: Synthesis, characterization and enzyme inhibitory properties
Yilmaz_2021_J.Biomol.Struct.Dyn__1Unravelling the phenolic compound reserves, antioxidant and enzyme inhibitory activities of an endemic plant species, Achillea pseudoaleppica
Yin_2021_Anat.Rec.(Hoboken)__Acupuncture therapy for Alzheimer's disease: The effectiveness and potential mechanisms
Yin_2021_Biotechnol.Lett__Expression and kinetic analysis of carboxylesterase LmCesA1 from Locusta migratoria
Yin_2021_J.Cell.Mol.Med__Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway
Yip_2021_Br.J.Clin.Pharmacol_87_2572Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine
Yoda_2021_New.Phytol_232_1999Strigolactone biosynthesis catalyzed by cytochrome P450 and sulfotransferase in sorghum
Yokoi_2021_IBRO.Neurosci.Rep_11_1Reversal of motor-skill transfer impairment by trihexyphenidyl and reduction of dorsolateral striatal cholinergic interneurons in Dyt1 GAG knock-in mice
Yokokawa_2021_Eur.J.Drug.Metab.Pharmacokinet__Effect of UGT1A1, CYP3A and CES Activities on the Pharmacokinetics of Irinotecan and its Metabolites in Patients with UGT1A1 Gene Polymorphisms
Yonekawa_2021_Bioorg.Med.Chem.Lett_47_128206l-Hypaphorine and d-hypaphorine: Specific antiacetylcholinesterase activity in rat brain tissue
Yoneten_2021_Cancer.Biomark__Decreased serum levels of glycerol-3- phosphate dehydrogenase 1 and monoacylglycerol lipase act as diagnostic biomarkers for breast cancer
Yoo_2021_Curr.Issues.Mol.Biol_43_405Immature Persimmon Suppresses Amyloid Beta (Abeta) Mediated Cognitive Dysfunction via Tau Pathology in ICR Mice
Yoo_2021_Sci.Rep_11_17914Cacao powder supplementation attenuates oxidative stress, cholinergic impairment, and apoptosis in D-galactose-induced aging rat brain
Yoon_2021_Biol.Psychiatry__cAMP Signaling-Mediated Phosphorylation of Diacylglycerol Lipase alpha Regulates Interaction With Ankyrin-G and Dendritic Spine Morphology
Yoon_2021_Medicine.(Baltimore)_100_e27252Cognitive decline according to amyloid uptake in patients with poststroke cognitive impairment
Yoshida_2021_Methods.Enzymol_648_187Ideonella sakaiensis, PETase, and MHETase: From identification of microbial PET degradation to enzyme characterization
Yoshida_2021_Nat.Commun_12_1848Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice
Yoshida_2021_Sci.Rep_11_11883Enhancement of protein thermostability by three consecutive mutations using loop-walking method and machine learning
Yoshikawa_2021_Commun.Biol_4_343Mutations in hik26 and slr1916 lead to high-light stress tolerance in Synechocystis sp. PCC6803
Yoshimaru_2021_Pediatr.Int__Reevaluation of Concurrent AChE and HE staining for Hirschsprung's disease
Yoshimaru_2021_Surg.Today_51_181Acetylcholinesterase staining for the pathological diagnosis of Hirschsprung's disease
Yoshioka_2021_J.Agric.Food.Chem__Inhibitory Activities of Sulfur Compounds in Garlic Essential Oil against Alzheimer's Disease-Related Enzymes and Their Distribution in the Mouse Brain
You_2021_FASEB.J_35_e21205CRISPR/Cas9-mediated genome editing of Schistosoma mansoni acetylcholinesterase
You_2021_FEBS.J__Structural basis for substrate specificity of the peroxisomal acyl-CoA hydrolase MpaH' involved in mycophenolic acid biosynthesis
You_2021_Pest.Manag.Sci__The overexpression and variant of a P450 gene CYP6G4 associated with propoxur resistance in the housefly, Musca domestica L
Youn_2021_Psychiatry.Investig__The Behavioral Effects of Combination Therapy of Memantine and Acetylcholinesterase Inhibitors Compared with Acetylcholinesterase Inhibitors Alone in Patients with Moderate Alzheimer's Dementia: A Double-Blind Randomized Placebo-Controlled Trial
Young_2021_Ann.Geriatr.Med.Res_25_170Cardiovascular Complications of Acetylcholinesterase Inhibitors in Patients with Alzheimer's Disease: A Narrative Review
Yousafi_2021_Saudi.J.Biol.Sci_28_2197In silico annotation of unreviewed acetylcholinesterase (AChE) in some lepidopteran insect pest species reveals the causes of insecticide resistance
Yu_2021_ACS.Catalysis_11_11733Functional Characterization and Crystal Structure of the Bifunctional Thioesterase Catalyzing Epimerization and Cyclization in Skyllamycin Biosynthesis
Yu_2021_AMB.Express_11_108Synthesis of ellagic acid glucoside using glucansucrase from Leuconostoc and characterization of this glucoside as a functional neuroprotective agent
Yu_2021_Analyst__A photoelectrochemical sensor based on an acetylcholinesterase-CdS/ZnO-modified extended-gate field-effect transistor for glyphosate detection
Yu_2021_Angew.Chem.Int.Ed.Engl_60_3679Inverting the Enantiopreference of Nitrilase-Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror-Image Strategy
Yu_2021_Ann.Transl.Med_9_332Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma
Yu_2021_Bioorg.Chem_117_105404Acylphloroglucinol trimers from Callistemon salignus seeds: Isolation, configurational assignment, hAChE inhibitory effects, and molecular docking studies
Yu_2021_Fish.Shellfish.Immunol__Comparative transcriptome analysis of Chinese grass shrimp (Palaemonetes sinensis) hepatopancreas under ectoparasitic isopod (Tachaea chinensis) infection
Yu_2021_Food.Chem_366_130650Lipase-catalyzed two-step esterification for solvent-free production of mixed lauric acid esters with antibacterial and antioxidative activities
Yu_2021_Foods_10_Effect of Chitosan Coatings with Cinnamon Essential Oil on Postharvest Quality of Mangoes
Yu_2021_J.Mater.Chem.B__Butyrylcholinesterase nanodepots with enhanced prophylactic and therapeutic performance for acute organophosphorus poisoning management
Yu_2021_Phytochemistry_193_112982Thirteen cyathane diterpenoids with acetylcholinesterase inhibitory effects from the fungus Cyathus africanus
Yuan_2021_Clin.Lab_67_Clinical Evaluation and Test of a Modified Lp-PLA2 Kit in Diagnosing Atherosclerosis
Yuksel_2021_Iran.J.Pharm.Res_20_422Phytochemicals Analysis and Some Bioactive Properties of Erica manipuliflora Salisb. (EMS); Antibacterial, Antiradical and Anti-lipid Peroxidation
Yuliani_2021_J.Neurochem_158_1307Central cholinergic function and metabolic changes in streptozotocin-induced rat brain injury
Yun_2021_J.Enzyme.Inhib.Med.Chem_36_1346Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer's disease agents
Yunusa_2021_J.Alzheimers.Dis.Rep_5_705Comparative Value of Cholinesterase Inhibitors and Memantine in Persons with Moderate-to-Severe Alzheimer's Disease in the United States: A Cost-Effectiveness Analysis
Yusuf_2021_Foods_10_Nutritional, Phytochemical Characteristics and In Vitro Effect on alpha-Amylase, alpha-Glucosidase, Lipase, and Cholinesterase Activities of 12 Coloured Carrot Varieties
Yves_2021_Brain.Res__147493NLX-101, a cortical 5-HT(1A) receptor biased agonist, reverses scopolamine-induced deficit in the delayed non-matching to position model of cognition
Zafar_2021_Drug.Des.Devel.Ther_15_2679Prospective Application of Two New Pyridine-Based Zinc (II) Amide Carboxylate in Management of Alzheimer's Disease: Synthesis, Characterization, Computational and in vitro Approaches
Zahir_2021_Life.(Basel)_11_Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide
Zahoor_2021_Heliyon_7_e06367Pharmacological evaluation and in-silico modeling study of compounds isolated from Ziziphus oxyphylla
Zaib_2021_Molecules_26_Hybrid Quinoline-Thiosemicarbazone Therapeutics as a New Treatment Opportunity for Alzheimer's DiseaseSynthesis, In Vitro Cholinesterase Inhibitory Potential and Computational Modeling Analysis
Zaki_2021_Appl.Microbiol.Biotechnol__New and potent production platform of the acetylcholinesterase inhibitor huperzine A by gamma-irradiated Alternaria brassicae under solid-state fermentation
Zakosek Pipan_2021_Sci.Rep_11_18098Treatment of canine cognitive dysfunction with novel butyrylcholinesterase inhibitor
Zambrano_2021_Int.J.Mol.Sci_22_Protective Role of a Donepezil-Huprine Hybrid against the beta-Amyloid (1-42) Effect on Human Erythrocytes
Zameer_2021_J.Appl.Toxicol__Alendronate reduces the cognitive and neurological disturbances induced by combined doses of d-galactose and aluminum chloride in mice
Zandi_2021_Arch.Iran.Med_24_233Prospects of Saffron and its Derivatives in Alzheimer's Disease
Zandona_2021_Arch.Toxicol__Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes
Zanfirescu_2021_Molecules_26_Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases
Zang_2021_Molecules_26_Claulansine F-Donepezil Hybrids as Anti-Alzheimer's Disease Agents with Cholinergic, Free-Radical Scavenging, and Neuroprotective Activities
Zara_2021_Molecules_27_Surface Interaction of Ionic Liquids: Stabilization of Polyethylene Terephthalate-Degrading Enzymes in Solution
Zarafyants_2021_Sud.Med.Ekspert_64_32[Forensic characteristics of the cardio-toxic effect of organophosphorus compounds]
Zaragoza-Puchol_2021_Molecules_26_Alkaloids Analysis of Habranthus cardenasianus (Amaryllidaceae), Anti-Cholinesterase Activity and Biomass Production by Propagation Strategies
Zare_2021_Drug.Chem.Toxicol__1Apoptosis is involved in paraoxon-induced histological changes in rat cerebellum
Zarei_2021_Heliyon_7_e06683Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4H)-yl)methyl) pyridin-1-ium derivatives (BOPs) as potential dual inhibitors of acetylcholinesterase and butyrylcholinesterase
Zaru_2021_FEBS.J__The Enzyme Portal: an integrative tool for enzyme information and analysis
Zein_2021_Prim.Care.Diabetes__Dipeptidyl peptidase-4 (DPP-IV) inhibitor was associated with mortality reduction in COVID-19 - A systematic review and meta-analysis
Zeng_2021_Clin.Infect.Dis_72_626Longitudinal Profile of Laboratory Parameters and Their Application in the Prediction for Fatal Outcome Among Patients Infected With SARS-CoV-2: A Retrospective Cohort Study
Zeng_2021_Food.Funct__Rapid screening of lipase inhibitors in licorice extract by using porcine pancreatic lipase immobilized on Fe(3)O(4) magnetic nanoparticles
Zeng_2021_J.Biotechnol__Immobilized lipase catalytic synthesis of phenolamides and their potential against alpha-glucosidase
Zeng_2021_Plant.J__The immune components EDS1 and PAD4 are required for cell death caused by overaccumulation of ceramides in Arabidopsis
Zengin_2021_Antioxidants.(Basel)_10_Comprehensive Biological and Chemical Evaluation of Two Seseli Species (S. gummiferum and S. transcaucasicum)
Zengin_2021_Antioxidants.(Basel)_10_2Chemical Composition and Biological Properties of Two Jatropha Species: Different Parts and Different Extraction Methods
Zengin_2021_J.Pharm.Biomed.Anal_198_114018Chemical composition, biological properties and bioinformatics analysis of two Caesalpina species: A new light in the road from nature to pharmacy shelf
Zengin_2021_Plants.(Basel)_10_Chemical Profiling and Biological Evaluation of Nepeta baytopii Extracts and Essential Oil: An Endemic Plant from Turkey
Zha_2021_Lett.Appl.Microbiol__Two polyurethanases PueA and PueB are major extracellular lipases partly secreted by the mediation of their cognate ABC exporter AprDEF in Pseudomonas protegens Pf-5
Zhan_2021_Mol.Med.Rep_24_Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma
Zhan_2021_Pestic.Biochem.Physiol_179_104973Influence of three insecticides targeting GABA receptor on fall armyworm Spodoptera frugiperda: Analyses from individual, biochemical and molecular levels
Zhang_2021_ACS.Sens__Fluorescent Determination of Butyrylcholinesterase Activity and Its Application in Biological Imaging and Pesticide Residue Detection
Zhang_2021_Acta.Pharmacol.Sin_42_1382New therapeutics beyond amyloid-beta and tau for the treatment of Alzheimer's disease
Zhang_2021_Anal.Chem__AND-Logic Strategy for Accurate Analysis of Alzheimer's Disease via Fluorescent Probe Lighted Up by Two Specific Biomarkers
Zhang_2021_Anal.Methods_13_2671A high-throughput screening assay for dipeptidyl peptidase-IV inhibitors using human plasma
Zhang_2021_Anticancer.Drugs_32_269EZH2-mediated lncRNA ABHD11-AS1 promoter regulates the progression of ovarian cancer by targeting miR-133a-3p
Zhang_2021_Appl.Biochem.Biotechnol__Identification and Characterization of a Novel Carboxylesterase Belonging to Family VIII with Promiscuous Acyltransferase Activity Toward Cyanidin-3-O-Glucoside from a Soil Metagenomic Library
Zhang_2021_BMC.Cancer_21_1156Development and validation of genomic and epigenomic signatures associated with tumor immune microenvironment in hepatoblastoma
Zhang_2021_Biochem.Biophys.Res.Commun_546_111Specific immobilization of lipase on functionalized 3D printing scaffolds via enhanced hydrophobic interaction for efficient resolution of racemic 1-indanol
Zhang_2021_Biomacromolecules__Substrate Engineering in Lipase-Catalyzed Selective Polymerization of d-/l-Aspartates and Diols to Prepare Helical Chiral Polyester
Zhang_2021_Bioorg.Chem_110_104783Paeonone A, a novel nonanortriterpenoid from the roots of Paeonia lactiflora
Zhang_2021_Bioorg.Chem_116_105387Design and synthesis of novel tacrine-dipicolylamine dimers that are multiple-target-directed ligands with potential to treat Alzheimer's disease
Zhang_2021_Biotechnol.Appl.Biochem__A stable biosensor based on chitosan-modified graphene for detecting organophosphorus pesticides
Zhang_2021_Biotechnol.Prog__e3218Efficient enzymatic synthesis of L-ascorbyl palmitate using CALB-embedded metal-organic framework
Zhang_2021_Chem.Biol.Drug.Des__Phthalimide-(N-alkylbenzylamine) cysteamide hybrids as multifunctional agents against Alzheimer's disease: Design, synthesis and biological evaluation
Zhang_2021_Chem.Biol.Interact_351_109744Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans
Zhang_2021_Chembiochem__A bi-enzymatic cascade pathway towards optically pure FAHFAs
Zhang_2021_Chemistry_10_3106Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans
Zhang_2021_Chemosphere_281_130791Effects of exogenous GR24 on biogas upgrading and nutrient removal by co-culturing microalgae with fungi under mixed LED light wavelengths
Zhang_2021_Colloids.Surf.B.Biointerfaces_200_111584Neuroprotective effects of maize tetrapeptide-anchored gold nanoparticles in Alzheimer's disease
Zhang_2021_Environ.Pollut_277_116767Combined effects of polyethylene and organic contaminant on zebrafish (Danio rerio): Accumulation of 9-Nitroanthracene, biomarkers and intestinal microbiota
Zhang_2021_Eur.J.Med.Chem_213_113154Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer's disease
Zhang_2021_Evid.Based.Complement.Alternat.Med_2021_6480381Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease
Zhang_2021_Food.Res.Int_143_110242UHPLC-QTOF-MS based metabolomics and biological activities of different parts of Eriobotrya japonica
Zhang_2021_Foods_10_The UHPLC-QTOF-MS Phenolic Profiling and Activity of Cydonia oblonga Mill. Reveals a Promising Nutraceutical Potential
Zhang_2021_Front.Cardiovasc.Med_8_795370The Potential of ANGPTL8 Antagonism to Simultaneously Reduce Triglyceride and Increase HDL-Cholesterol Plasma Levels
Zhang_2021_Front.Med__Research progress on FASN and MGLL in the regulation of abnormal lipid metabolism and the relationship between tumor invasion and metastasis
Zhang_2021_Front.Oncol_11_630257Clinical Relevance and Prognostic Value of the Neuronal Protein Neuroligin 2 in Breast Cancer
Zhang_2021_Front.Pharmacol_12_632757The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area
Zhang_2021_Front.Pharmacol_12_731453The Roles of Dipeptidyl Peptidase 4 (DPP4) and DPP4 Inhibitors in Different Lung Diseases: New Evidence
Zhang_2021_Front.Pharmacol_12_784202Alpha/Beta-Hydrolase Domain-Containing 6: Signaling and Function in the Central Nervous System
Zhang_2021_Int.Immunopharmacol_99_108035Astilbin ameliorates oxidative stress and apoptosis in D-galactose-induced senescence by regulating the PI3K/Akt/m-TOR signaling pathway in the brains of mice
Zhang_2021_Int.J.Biol.Macromol_184_92A reverse catalytic triad Asp containing loop shaping a wide substrate binding pocket of a feruloyl esterase from Lactobacillus plantarum
Zhang_2021_Int.J.Mol.Sci_22_Genome-Wide Identification of GDSL-Type Esterase/Lipase Gene Family in Dasypyrum villosum L. Reveals That DvGELP53 Is Related to BSMV Infection
Zhang_2021_J.Biol.Chem__100841Active site architecture of an acetyl xylan esterase indicates a novel cold adaptation strategy
Zhang_2021_J.Control.Release_329_1117Brain-targeted delivery of obidoxime, using aptamer-modified liposomes, for detoxification of organophosphorus compounds
Zhang_2021_J.Mater.Chem.B__A highly selective near infrared fluorescent probe for carboxylesterase 2 and its biological applications
Zhang_2021_J.Microbiol.Immunol.Infect__Attenuation of virulence in multiple serotypes (M1, M3, and M28) of Group A Streptococcus after the loss of secreted esterase
Zhang_2021_JCI.Insight_6_e148496Thyroid hormone synthesis continues despite biallelic thyroglobulin mutation with cell death
Zhang_2021_Medicine.(Baltimore)_100_e26462A simple noninvasive model to predict significant fibrosis in children with chronic hepatitis B
Zhang_2021_Molecules_26_Discovery of Three New Monoterpenoid Indole Alkaloids from the Leaves of Gardneria multiflora and Their Vasorelaxant and AChE Inhibitory Activities
Zhang_2021_Nat.Prod.Bioprospect__Diterpenoid Alkaloids from the Aerial Parts of Aconitum flavum Hand.-Mazz
Zhang_2021_Nutr.Clin.Pract__Evaluation of the effect of high protein supply on diaphragm atrophy in critically ill patients receiving prolonged mechanical ventilation
Zhang_2021_Pharmacol.Res_169_105630Profibrotic mechanisms of DPP8 and DPP9 highly expressed in the proximal renal tubule epithelial cells
Zhang_2021_ResearchSquare__The abundance of mRNA transcripts of bacteroidetal polyethylene terephthalate (PET) esterase genes may indicate a role in marine plastic degradation
Zhang_2021_Talanta_228_122268Smart nanozyme of silver hexacyanoferrate with versatile bio-regulated activities for probing different targets
Zhang_2021_World.J.Gastroenterol_27_3863PPARGC1A rs8192678 G>A polymorphism affects the severity of hepatic histological features and nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease
Zhang_2021_Zhongguo.Zhong.Yao.Za.Zhi_46_638[Construction and application of pharmacophore model of human carboxylesterase 2 inhibitors]
Zhang_2021_Zhonghua.Wei.Zhong.Bing.Ji.Jiu.Yi.Xue_33_740[Experimental study on liver injury induced by intraperitoneal hypertension under mechanical ventilation]
Zhang_2022_Front.Microbiol_12_803896The Bacteroidetes Aequorivita sp. and Kaistella jeonii Produce Promiscuous Esterases With PET-Hydrolyzing Activity
Zhao_2021_Ann.Clin.Transl.Neurol__Congenital myasthenic syndrome in China: genetic and myopathological characterization
Zhao_2021_Arch.Toxicol__Physiologically based kinetic modelling based prediction of in vivo rat and human acetylcholinesterase (AChE) inhibition upon exposure to diazinon
Zhao_2021_Bioorg.Chem_108_104656Multivalent butyrylcholinesterase inhibitor discovered by exploiting dynamic combinatorial chemistry
Zhao_2021_Bioorg.Chem_116_105307Bioactive phenylpropanoid derivatives from the fruits of Lycium ruthenicum Murr
Zhao_2021_Bioorg.Chem_119_105520Identification and synthesis of selective cholesterol esterase inhibitor using dynamic combinatorial chemistry
Zhao_2021_Chem.Biol.Interact__109571Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics
Zhao_2021_ChemMedChem_16_388Synthesis and Structure-Activity Relationships of 3-Arylisoquinolone Analogues as Highly Specific hCES2A Inhibitors
Zhao_2021_Chemosphere_279_130542Current insights into the microbial degradation for pyrethroids: strain safety, biochemical pathway, and genetic engineering
Zhao_2021_Chin.J.Nat.Med_19_454Bufotenine and its derivatives: synthesis, analgesic effects identification and computational target prediction
Zhao_2021_Curr.Drug.Metab__Comparison of the Inhibitory Effects of Clotrimazoleand Ketoconazole against Human Carboxylesterase 2
Zhao_2021_Food.Chem_354_129511Detection of organophosphorus pesticides by nanogold/mercaptomethamidophos multi-residue electrochemical biosensor
Zhao_2021_Food.Funct__Neuroprotective effects of NDEELNK from sea cucumber ovum against scopolamine-induced PC12 cell damage through enhancing energy metabolism and upregulation of the PKA/BDNF/NGF signaling pathway
Zhao_2021_Front.Med.(Lausanne)_8_761517COX-2/sEH Dual Inhibitor PTUPB Alleviates CCl (4) -Induced Liver Fibrosis and Portal Hypertension
Zhao_2021_Future.Med.Chem__Small-molecule inhibitors of carboxylesterase Notum
Zhao_2021_Inorg.Chem__Loading and Sustained Release of Pralidoxime Chloride from Swellable MIL-88B(Fe) and Its Therapeutic Performance on Mice Poisoned by Neurotoxic Agents
Zhao_2021_Int.J.Biol.Macromol_183_811Natural soluble epoxide hydrolase inhibitors from Alisma orientale and their potential mechanism with soluble epoxide hydrolase
Zhao_2021_Int.J.Biol.Macromol__Characterization of a novel lipase from Bacillus licheniformis NCU CS-5 for applications in detergent industry and biodegradation of 2,4-D butyl ester
Zhao_2021_J.Chromatogr.A_1653_462443Development and characterization of a selective chromatographic approach to the rapid discovery of ligands binding to muscarinic-3 acetylcholine receptor
Zhao_2021_J.Dermatol.Sci_102_7Circular RNA circ_0079593 enhances malignant melanoma progression by the regulation of the miR-573/ABHD2 axis
Zhao_2021_J.Enzyme.Inhib.Med.Chem_36_248Production, purification and biochemical characterisation of a novel lipase from a newly identified lipolytic bacterium Staphylococcus caprae NCU S6
Zhao_2021_J.Med.Chem__Structural Insights into Notum Covalent Inhibition
Zhao_2021_J.Orthop.Surg.Res_16_364NDRG1 regulates osteosarcoma cells via mediating the mitochondrial function and CSCs differentiation
Zhao_2021_Mol.Metab__101201Notum Deacylates Octanoylated Ghrelin
Zhao_2021_Molecules_26_Chemical Composition and Biological Activities of Essential Oils from the Leaves, Stems, and Roots of Kadsura coccinea
Zhao_2021_Prog.Lipid.Res_83_101112Phosphatidylserine-specific phospholipase A1: A friend or the devil in disguise
Zhao_2021_Proteins__Mycobacterium tuberculosis puromycin hydrolase displays a prolyl oligopeptidase fold and an acyl aminopeptidase activity
Zhao_2021_Talanta_235_122784A near-infrared light triggered fluormetric biosensor for sensitive detection of acetylcholinesterase activity based on NaErF(4): 0.5 % Ho(3+)@NaYF(4) upconversion nano-probe
Zhao_2021_World.J.Microbiol.Biotechnol_37_212Characterization and genomic analysis of an efficient dibutyl phthalate degrading bacterium Microbacterium sp. USTB-Y
Zheleva-Dimitrova_2021_Food.Chem.Toxicol__112446Comprehensive chemical characterization and biological evaluation of two Acacia species: A. nilotica and A. ataxacantha
Zheleva-Dimitrova_2021_Plants.(Basel)_10_Innovative Biochemometric Approach to the Metabolite and Biological Profiling of the Balkan Thistle (Cirsium appendiculatum Griseb.), Asteraceae
Zheng_2021_Brain.Res__147672Wheat Embryo Globulin Nutrients Ameliorate D-galactose and Aluminum Chloride-Induced Cognitive Impairment in Rats
Zheng_2021_Carbohydr.Polym_253_117255Metabolic degradation of lentinan in liver mediated by CYP450 enzymes and epoxide hydrolase
Zheng_2021_Chembiochem_22_996A High-Throughput Screening Method for the Directed Evolution of Hydroxynitrile Lyase towards Cyanohydrin Synthesis
Zheng_2021_J.Hazard.Mater_423_127017Computational biotransformation of polyethylene terephthalate by depolymerase: A QM/MM approach
Zhong-Johnson_2021_Sci.Rep_11_928An absorbance method for analysis of enzymatic degradation kinetics of poly(ethylene terephthalate) films
Zhou_2021_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159090DECR1 directly activates HSL to promote lipolysis in cervical cancer cells
Zhou_2021_Biomacromolecules__Synthesis, Characterization, and Simulation of Four-Armed Megamolecules
Zhou_2021_Biomarkers__1Cholinesterase homozygous genotype as susceptible biomarker of hypertriglyceridemia for pesticide-exposed agricultural workers
Zhou_2021_Biomed.Pharmacother_146_112556The biological activities of butyrylcholinesterase inhibitors
Zhou_2021_Biosens.Bioelectron_196_113723Dual-fiber optic bioprobe system for triglyceride detection using surface plasmon resonance sensing and lipase-immobilized magnetic bead hydrolysis
Zhou_2021_Biotechnol.Biofuels_14_156Magnetic COFs as satisfied support for lipase immobilization and recovery to effectively achieve the production of biodiesel by great maintenance of enzyme activity
Zhou_2021_Chem.Biol.Drug.Des_98_997Synthesis and activities of acetylcholinesterase inhibitors
Zhou_2021_Chem.Biol.Drug.Des__Synthesis and biological activities of butyrylcholinesterase inhibitors
Zhou_2021_Clin.Transl.Med_11_e449Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1
Zhou_2021_Front.Immunol_12_670427Pig Liver Esterases Hydrolyze Endocannabinoids and Promote Inflammatory Response
Zhou_2021_J.Hazard.Mater_416_126142Physiological and transcriptomic changes of zebrafish (Danio rerio) embryos-larvae in response to 2-MIB exposure
Zhou_2021_J.Med.Chem_64_1844Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate
Zhou_2021_Neuroreport_32_727Poria cocos polysaccharide attenuates damage of nervus in Alzheimer's disease rat model induced by D-galactose and aluminum trichloride
Zhu_2021_Appl.Microbiol.Biotechnol__Effect of cross-linked enzyme aggregate strategy on characterization of sn-1,3 extracellular lipase from Aspergillus niger GZUF36
Zhu_2021_Biosens.Bioelectron_196_1136913D origami paper-based ratiometric fluorescent microfluidic device for visual point-of-care detection of alkaline phosphatase and butyrylcholinesterase
Zhu_2021_Biosensors.(Basel)_11_Nanozyme-Participated Biosensing of Pesticides and Cholinesterases: A Critical Review
Zhu_2021_Front.Genet_12_693538Structure and Function of Pancreatic Lipase-Related Protein 2 and Its Relationship With Pathological States
Zhu_2021_J.Agric.Food.Chem__Structural Insights into a Novel Esterase from the East Pacific Rise and Its Improved Thermostability by a Semirational Design
Zhu_2021_J.Biosci.Bioeng__Combining fermentation to produce O-succinyl-l-homoserine and enzyme catalysis for the synthesis of l-methionine in one pot
Zhu_2021_Molecules_26_Chemical Constituents from the Wild Atractylodes macrocephala Koidz and Acetylcholinesterase Inhibitory Activity Evaluation as Well as Molecular Docking Study
Zhu_2021_Pharmacol.Biochem.Behav__173209Donepezil prevents morphine tolerance by regulating N-methyl-d-aspartate receptor, protein kinase C and CaM-dependent kinase II expression in rats
Zhu_2021_Trials_22_688Efficiency of donepezil in elderly patients undergoing orthopaedic surgery due to underlying post-operative cognitive dysfunction: study protocol for a multicentre randomised controlled trial
Zilbeyaz_2021_Bioorg.Med.Chem_40_116194Design and synthesis of garlic-related unsymmetrical thiosulfonates as potential Alzheimer's disease therapeutics: In vitro and in silico study
Zimetti_2021_Oxid.Med.Cell.Longev_2021_6695796Connection between the Altered HDL Antioxidant and Anti-Inflammatory Properties and the Risk to Develop Alzheimer's Disease: A Narrative Review
Zou_2021_Int.J.Biol.Macromol__Novel sampangine derivatives as potent inhibitors of Cu(2+)-mediated amyloid-beta protein aggregation, oxidative stress and inflammation
Zou_2021_J.Proteomics__104124Use of data-independent acquisition mass spectrometry for comparative proteomics analyses of sera from pregnant women with intrahepatic cholestasis of pregnancy
Zou_2021_Open.Biol_11_200306Alterations of the endocannabinoid system and its therapeutic potential in autism spectrum disorder
Zrimec_2021_mBio_12_e0215521Plastic-Degrading Potential across the Global Microbiome Correlates with Recent Pollution Trends
Zueva_2021_Chem.Biol.Interact_345_109558Protective effects of m-(tert-butyl) trifluoroacetophenone, a transition state analogue of acetylcholine, against paraoxon toxicity and memory impairments
Zueva_2021_Chem.Biol.Interact__109646alpha-tocopherol, a slow-binding inhibitor of acetylcholinesterase
da Costa Rodrigues_2021_Chem.Biol.Interact_351_109736A new arylsulfanyl-benzo-2,1,3-thiadiazoles derivative produces an anti-amnesic effect in mice by modulating acetylcholinesterase activity
da Costa_2021_Proteins__Assessment of the PETase conformational changes induced by poly(ethylene terephthalate) binding
da Luz_2021_Sci.Total.Environ_780_146553Can use of hydroxychloroquine and azithromycin as a treatment of COVID-19 affect aquatic wildlife? A study conducted with neotropical tadpole
da Motta_2021_Chem.Biol.Interact__109772Target enzymes in oxaliplatin-induced peripheral neuropathy in Swiss mice: A new acetylcholinesterase inhibitor as therapeutic strategy
da Silva_2021_Neurochem.Res__Multitarget Effect of 2-(4-(Methylthio)phenyl)-3-(3-(piperidin-1-yl)propyl)thiazolidin-4-one in a Scopolamine-Induced Amnesic Rat Model
da Silva_2021_Neurotox.Res_39_467Anacardic Acid Complexes as Possible Agents Against Alzheimer's Disease Through Their Antioxidant, In vitro, and In silico Anticholinesterase and Ansiolic Actions
de ARC_2021_Bioprocess.Biosyst.Eng__Computational and experimental analysis on the preferential selectivity of lipases for triglycerides in Licuri oil
de Almeida_2021_Mini.Rev.Med.Chem__A Review on the in vitro Evaluation of the Anticholinesterase Activity Based on Ellman's Method
de Andrade Ramos_2021_RSC.Med.Chem_12_1154Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties
de Araujo_2021_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1179_122826Is zebrafish (Danio rerio) water tank model applicable for the assessment of glucocorticoids metabolism? The budesonide assessment
de Farias_2021_J.Environ.Sci.Health.A.Tox.Hazard.Subst.Environ.Eng__1Neuromotor activity inhibition in zebrafish early-life stages after exposure to environmental relevant concentrations of caffeine
de Moraes Meine_2021_Int.J.Dev.Neurosci__Acute hypermethioninemia impairs redox homeostasis and acetylcholinesterase activity in the hippocampus, striatum and cerebellum of young rats
de Oliveira Pereira_2021_Neurotoxicol__Dihydropyrimidinone-derived selenoesters efficacy and safety in an in vivo model of Abeta aggregation
de Oliveira Ribeiro_2021_Environ.Sci.Pollut.Res.Int__Comparative effects of oral exposure to 2, 4, 6-tribromophenol and decabromodiphenyl ether in Nile tilapia
de Oliveira_2021_Chem.Biodivers__Extraction Yield, Chemical Composition, Preliminary Toxicity of Bignonia nocturna (Barb.Rodr.) L.G. Lohmann (Bignoniaceae) Essential Oil and In silico evaluation of the interaction
de Oliveira_2021_Food.Funct_12_9820Bioactivity screening of pinho (Araucaria Angustifolia (Bertol.) Kuntze) seed extracts: the inhibition of cholinesterases and alpha-amylases, and cytotoxic and anti-inflammatory activities
de Oliveira_2021_Nat.Prod.Res__1Biotic stress caused by in vitro co-inoculation enhances the expression of acetylcholinesterase inhibitors by fungi
de Oliveira_2021_Parasitol.Res_120_1Developmental changes in larvae of the oriental latrine fly, Chrysomya megacephala, exposed to deltamethrin
de Paula_2021_Aquat.Toxicol_237_105874Effects of copper on an omnivorous (Astyanax altiparanae) and a carnivorous fish (Hoplias malabaricus): A comparative approach
de Queiros Eugenio_2021_J.Biotechnol__Experimental and mathematical modeling approaches for biocatalytic post-consumer poly(ethylene terephthalate) hydrolysis
de Sa_2021_Mar.Drugs_19_Anthraquinones, Diphenyl Ethers, and Their Derivatives from the Culture of the Marine Sponge-Associated Fungus Neosartorya spinosa KUFA 1047
de Saint Germain_2021_Methods.Mol.Biol_2309_219Synthesis of Profluorescent Strigolactone Probes for Biochemical Studies
de Saint Germain_2021_Plant.Commun_2_100166A Phelipanche ramosa KAI2 protein perceives strigolactones and isothiocyanates enzymatically
de Sousa Fonseca_2021_Bioprocess.Biosyst.Eng__Immobilization of Amano lipase AK from Pseudomonas fluorescens on different types of chitosan-containing supports: use in the kinetic resolution of rac-indanol
de Souza Cardoso_2021_Mol.Cell.Endocrinol__111157Neuroprotection elicited by resveratrol in a rat model of hypothyroidism: possible involvement of cholinergic signaling and redox status
de Souza_2021_Colloids.Surf.B.Biointerfaces_203_111721The liquid crystalline phase behaviour of a nasal formulation modifies the brain disposition of donepezil in rats in the treatment of Alzheimer's disease
de Vries_2021_Plant.Biotechnol.J__CRISPR-Cas9 Editing of CAFFEOYL SHIKIMATE ESTERASE 1 and 2 Shows Their Importance and Partial Redundancy in Lignification in Populus tremula x P. alba
de la Rubia Orti_2021_Nutrients_13_Possible Role of Butyrylcholinesterase in Fat Loss and Decreases in Inflammatory Levels in Patients with Multiple Sclerosis after Treatment with Epigallocatechin Gallate and Coconut Oil: A Pilot Study
do Canto_2021_J.Mol.Model_27_46Computational studies of polyurethanases from Pseudomonas
van Egmond_2021_Annu.Rev.Pharmacol.Toxicol_61_441Targeting Endocannabinoid Signaling: FAAH and MAG Lipase Inhibitors
van Haren_2021_Biomolecules_11_1357Esterase-Sensitive Prodrugs of a Potent Bisubstrate Inhibitor of Nicotinamide N-Methyltransferase (NNMT) Display Cellular Activity
van Mierlo_2021_Brain.Behav__Rivastigmine for minor visual hallucinations in Parkinson's disease: A randomized controlled trial with 24 months follow-up
van der Zee_2021_Mov.Disord_36_642Cholinergic Denervation Patterns Across Cognitive Domains in Parkinson's Disease
witek_2021_Int.J.Mol.Sci_22_LC-ESI-QTOF-MS/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer