Piperidin

Inhibitor	Main targeted enzyme families	Type	Structure
CHEMBL5176915	Monoglyceridelipase_lysophospholip	Pyridine Piperidine Trifluoro
MAGL-IN-10-Cpd28	Monoglyceridelipase_lysophospholip	Pyridine Piperidine Trifluoro Sulfur Compound
Galantamine-benzylpyridine-C2	ACHE BCHE	Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Pyridine Benzazepin Azepane
SCHEMBL23211786	Monoglyceridelipase_lysophospholip	Piperidine Oxazine
CHEMBL5195416	ACHE	Monoamine-oxidase-inhibitor Multitarget Piperidine Antioxidant
Flucopride	ACHE	Multitarget 5-HT-receptor-ligand Piperidine
SCHEMBL22488617	Monoglyceridelipase_lysophospholip	Piperidine Trifluoro Oxazine
SCHEMBL21061872	Monoglyceridelipase_lysophospholip	Benzoxazine Piperidine
SCHEMBL22491361	Monoglyceridelipase_lysophospholip	Benzoxazine Piperidine Indole
SCHEMBL22462763	Monoglyceridelipase_lysophospholip	Piperidine Trifluoro Oxazine
MAGL11	Monoglyceridelipase_lysophospholip	Piperidine Formamide
SW-17	Epoxide_hydrolase	Sulfur Compound Multitarget Thiazole Piperidine Carboxamide
Sulphostin	DPP4N_Peptidase_S9	Natural Sulfur Compound Piperidine
Benzylpiperidin-methylene-methoxy-dihydro-inden-one	ACHE	Inden BACE1-inhibitor Derivative of Donepezil Multitarget Piperidine
Periciazine	BCHE	Not A\/B H target Phenothiazine Multitarget Drug Sulfur Compound Piperidine Cyanide
Colchicine-donepezil-SBN-284-3x	ACHE BCHE	Multitarget Derivative of Donepezil Piperidin
sEH-HDAC6-Cpd28g	Epoxide_hydrolase	Urea derivative Multitarget HDAC inhibitor Piperidine Carboxamide
GL-B437	Epoxide_hydrolase	Urea derivative Adamantyl Piperidine Carboxamide
Contilistat		Multitarget Histamine-Receptor3-H3-Antagonist Monoamine-oxidase-inhibitor Piperidine Indole HDAC inhibitor prop-2-yn-1-yl
MR33317	ACHE	Multitarget 5-HT-receptor-ligand Piperidine
Ezurpimtrostat	Palmitoyl-protein_thioesterase	Piperidine Quinoline
Lyplal1-IN-1	LYsophospholipase_carboxylesterase	Piperidine Urea derivative Triazol Morpholine Pyrimidine
75J-34n	DPP4N_Peptidase_S9	Piperidine Imidazole Purine Cyanide
X20419	Thioesterase	Piperazine Piperidine Pyrimidine Carboxamide Indole
ADS031	ACHE	Histamine-Receptor3-H3-Antagonist Multitarget Piperidine Naphthalen
CHEMBL459756	ACHE BCHE	Histamine-Receptor3-H3-Antagonist Multitarget Piperidine
FUB833	ACHE BCHE	Acridine Derivative of Tacrine Alkyl linked bis-ligand Histamine-Receptor3-H3-Antagonist Multitarget Piperidine
Piperidine-4-carboxamide-alkyl-tacrine-cpd16	ACHE BCHE	Acridine Derivative of Tacrine Alkyl linked bis-ligand Piperidine Carboxamide
Coumarin-dimethoxyphenyl-methylpiperidine-carboxamise-cpd3b	ACHE	Coumarin Piperidine Carboxamide Derivative of Donepezil Chromen
Benzylpiperidin-methylsulfonyl-indol-acryloyl-phenyl-acetamide-cpd6b	BCHE ACHE	Multitarget Indole Carboxamide Piperidine Derivative of Donepezil Sulfur Compound
Benzylpiperidin-oxoindolin-acetamide-Cpd23	ACHE	Derivative of Donepezil Piperidine Indole
Indole-piperidine-amide-cpd23a	ACHE	Multitarget Indole Carboxamide Derivative of Donepezil BACE1-inhibitor Piperidine
SB-1448	BCHE ACHE	Multitarget Derivative of Donepezil BACE1-inhibitor Piperidine
Triazole-carbonylpiperidin-diphenylazetidin-2-one-5d	Monoglyceridelipase_lysophospholip	Piperidine Triazol Azetidin
Triazole-carbonylpiperidin-diphenylazetidin-2-one-5d-F28		Piperidine Triazol Azetidin
Benzo-triazole-carbonylpiperidin-benzodioxol-fluorophenylazetidin-2-one-5v	Monoglyceridelipase_lysophospholip	Benzodioxo Piperidine Triazol Azetidin
M-18C	Monoglyceridelipase_lysophospholip	Carboxamide Piperidine Indole
SCHEMBL3454366	Epoxide_hydrolase	Urea derivative Piperidine
SCHEMBL3454366-Boc	Epoxide_hydrolase	Urea derivative tert-Butyl Piperidine
SCHEMBL3454366-Isobutyryl	Epoxide_hydrolase	Piperidine Urea derivative
Benzofuran-carbonyl-benzyloxy-piperidine-Cpd8	ACHE	Benzofuran Piperidine Acaricide
J8-A34	ACHE	Piperidine Sulfur Compound Sulfonamide Quinoline Derivative of Donepezil
Compound5d-Benzylpiperidine-Phenyl-oxadiazol-thiol	ACHE	anti-Abeta-aggregation Sulfur Compound BACE1-inhibitor Piperidine Multitarget Carboxamide Oxadiazol Derivative of Donepezil Cyanide
C4I-7QHE	BCHE	Acridine Alkyl linked bis-ligand Derivative of Tacrine Carboxamide Derivative of Donepezil Naphthalen Piperidine
C0I-7QHD	BCHE	Acridine Alkyl linked bis-ligand Derivative of Tacrine Carboxamide Derivative of Donepezil Indole Piperidine
JZP-MA-11	ABHD6-Lip	Sulfur Compound PET probe Thiadiazol Piperidine Carbamate
4c2-AChE-IN-24	ACHE	Sulfur Compound Multitarget Piperidine
AZ12756122	Thioesterase	Sulfonamide Piperidine Cyanide Sulfur Compound
AA692		Piperidine Triazol tert-Butyl
Loperamide	Carb_B_Chordata	Piperidine Drug Not A\/B H target Opioid analgesic
DFAH-12	BCHE ACHE	Piperidine Hydroxycinnamic-ester Multitarget Antioxidant Derivative of Donepezil
ZLWH-23	ACHE	Piperidine GSK-3 kinase inhibitor Carboxamide Multitarget Indole Cyclopropyl beta-carboline
Chlorophenyl-sulfonyl-quinolin-piperidine-carboxamide-4d	Epoxide_hydrolase	Piperidine Sulfur Compound Sulfonamide Carboxamide Multitarget
m-Amino-donepezil	ACHE	Derivative of Donepezil Piperidine Inden
NSD1819	Monoglyceridelipase_lysophospholip	Benzodioxo Piperidine Triazol Azetidin
MAGL23	Monoglyceridelipase_lysophospholip	Piperidine
MAGL17b	Monoglyceridelipase_lysophospholip	Piperidine
Lalistat-alkyne-probe	Acidic_Lipase 6_AlphaBeta_hydrolase Cutinase Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip	Piperidine Lipase inhibitor Sulfur Compound Thiadiazol Alkyne ABPP-Probe
ML226	ABHD11-Acetyl_transferase Lipase_3	Triazol Piperidine
Fotagliptin	DPP4N_Peptidase_S9	Gliptin Cyanide Piperidine Triazine
CHEMBL57478	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Piperidine Indole
3-butyl-6-benzyloxyphthalide-Mannich-base-7d	ACHE	Monoamine-oxidase-inhibitor Multitarget Piperidine Benzofuran
TPPU-6-Chlorotacrine-12c	Epoxide_hydrolase ACHE	Multitarget Derivative of Tacrine Trifluoro Piperidine Urea derivative Alkyl linked bis-ligand
Fragment-886	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Piperidine Pyrazole
Fragment-201	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Piperidine Oxadiazol
Fragment-634	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Cyanide Piperidine
Piperine	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Piperidine Natural Benzodioxo
Benzothiazole-analogue-13f	Epoxide_hydrolase	Benzothiazol Piperidine Sulfur Compound Sulfonamide Carboxamide
FAAH_sEH_4.5	Epoxide_hydrolase	Multitarget FAAH inhibitor Benzothiazol Piperidine Sulfur Compound Carboxamide
CHEMBL2313198	Epoxide_hydrolase	Piperidine Sulfur Compound Sulfonamide Carboxamide Trifluoro
CHEMBL3233607-S0G-3WKA	Epoxide_hydrolase	Piperidine Pyrimidine
H0L-7D9O	ACHE	Inden Piperidine Derivative of Donepezil
H1R-7D9Q	ACHE	Inden Piperidine Derivative of Donepezil
H0R-7D9P	ACHE	Inden Piperidine Derivative of Donepezil
WAY-121898	Cholesterol_esterase	Carbamate Piperidine Phenoxyphenyl
XP7-7L4U	Monoglyceridelipase_lysophospholip	Piperidine Pyrrolidine
SCHEMBL19421059	Monoglyceridelipase_lysophospholip	Azaspiro Piperidine
SCHEMBL19834081	Monoglyceridelipase_lysophospholip	Benzoxazine Piperidine
ABC47	abh_upf0017 CGI-58_ABHD5_ABHD4	Carbamate Piperidine N-hydroxyhydantoin Phenoxyphenyl
ABC51	CGI-58_ABHD5_ABHD4	Carbamate Piperidine N-hydroxyhydantoin Phenoxyphenyl
JJH251		Carbamate Piperidine N-hydroxyhydantoin
WHP313	S9N_PREPL_Peptidase_S9	Piperidine
JJH221		Carbamate Piperidine N-hydroxyhydantoin tert-Butyloxycarbonyl tert-Butyl
ABC44	Palmitoyl-protein_thioesterase	Carbamate Piperidine N-hydroxyhydantoin
DH376	Lipase_3	Piperidine Triazol Urea derivative
ML211	LYsophospholipase_carboxylesterase ABHD11-Acetyl_transferase	Piperidine Triazol tert-Butyl
KT185	ABHD6-Lip	Piperidine Triazol
KT203	ABHD6-Lip	Piperidine Triazol
KT182	ABHD6-Lip	Piperidine Triazol
Pyranone-carbamate-cpd7p	BCHE	Carbamate Piperidine Antioxidant
6SAM-cpd13	BCHE	Multitarget Piperidine Inden Monoamine-oxidase-inhibitor Carbamate
6RUA-3a	BCHE	Sulfur Compound Sulfonamide Coumarin Piperidine Carboxamide Naphthalen Chromen
JU5	BCHE	Coumarin Piperidine Carboxamide Naphthalen Sulfur Compound Chromen
JUB	BCHE	Piperidine Piperazine NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole Sulfur Compound Sulfonamide Naphthalen
75M-5T4F	DPP4N_Peptidase_S9	Piperidine Quinazoline Cyanide Purine
75L-5T4E	DPP4N_Peptidase_S9	Piperidine Pyrimidine Quinazoline Purine
75N-5T4B	DPP4N_Peptidase_S9	Piperidine Quinazoline Purine
TUPS	Epoxide_hydrolase	Piperidine Urea derivative Trifluoro Sulfur Compound Sulfonamide
UW-MD-71	ACHE BCHE Cholinesterase	Piperidine Quinazoline Multitarget Histamine-Receptor3-H3-Antagonist
FG1912	ACHE	GSK-3 kinase inhibitor Multitarget Pyridine Piperidine Cyclopropyl Carboxamide Derivative of Donepezil
GD29	ACHE	GSK-3 kinase inhibitor Multitarget Thiazole Pyridine Piperidine Cyclopropyl Carboxamide Sulfur Compound Derivative of Donepezil
Donecopride	ACHE	Multitarget 5-HT-receptor-ligand Derivative of Donepezil Piperidine
RS67333	ACHE	Multitarget 5-HT-receptor-ligand Piperidine
Phenolic-deriv-Donecopride-4	ACHE	Multitarget 5-HT-receptor-ligand Derivative of Donepezil Piperidine
Phenolic-deriv-Donecopride-20	ACHE	Carbamate Multitarget 5-HT-receptor-ligand Derivative of Donepezil Piperidine
Sigma1R-ACHE-6a	ACHE	Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil
Sigma1R-ACHE-6b	ACHE	Multitarget 5-HT-receptor-ligand Piperidine Sigma1R Indole Derivative of Donepezil
AS2586144	Epoxide_hydrolase	Piperidine Benzoate Cyclopropyl
6F7Q-cpd11	BCHE	Multitarget Antioxidant Piperidine Quinoline Metal ion chelator Inden Carboxamide
Lalistat-1	Acidic_Lipase Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase 6_AlphaBeta_hydrolase	Piperidine Lipase inhibitor Sulfur Compound Thiadiazol
Lalistat-2	Acidic_Lipase Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase 6_AlphaBeta_hydrolase	Piperidine Lipase inhibitor Sulfur Compound Thiadiazol
5LKR-6yc	BCHE	Piperidine Carboxamide Naphthalen
Donepezil-derivative-DZ7	ACHE	Piperidine Derivative of Donepezil Inden
Donepezil-derivative-DZ0	ACHE	Piperidine Derivative of Donepezil Inden
5DYT-5hb	BCHE	Piperidine Derivative of Donepezil Sulfonamide Sulfur Compound Naphthalen
5DYY-5hh	BCHE	Piperidine Derivative of Donepezil Sulfonamide Sulfur Compound Naphthalen
TAM1	Thioesterase	Piperidine Benzofuran
Coumestan-cpd32	Thioesterase	Piperidine Benzofuran
Coumestan-cpd8	Thioesterase	Piperidine Benzofuran Chromen
TAM16	Thioesterase	Piperidine Carboxamide Benzofuran
CHEMBL3687984	DPP4N_Peptidase_S9	Cyanide Piperidine Purine
CHEMBL3112966	DPP4N_Peptidase_S9	Piperidine
CHEMBL1951424	DPP4N_Peptidase_S9	Piperidine Cyanide Quinoline Pyrrolidine
Piperidinyl-1,2,3-triazole-urea-inhibitor-11	LYsophospholipase_carboxylesterase	Piperidine Urea derivative Triazol
Piperidinyl-1,2,3-triazole-urea-inhibitor-12	LYsophospholipase_carboxylesterase	Piperidine Urea derivative Triazol
Piperidinyl-1,2,3-triazole-urea-inhibitor-2	LYsophospholipase_carboxylesterase Carb_B_Chordata ABHD11-Acetyl_transferase PAF-Acetylhydrolase Cholesterol_esterase	Piperidine Urea derivative Triazol
SCHEMBL13923509	DPP4N_Peptidase_S9	Pyrrolidine Piperidine
TPPU-methyl	Epoxide_hydrolase	Trifluoro Piperidine Urea derivative
SCHEMBL15272467	Epoxide_hydrolase	Trifluoro Piperidine Urea derivative
TPPU	Epoxide_hydrolase	Trifluoro Piperidine Urea derivative
CHEMBL469792	Epoxide_hydrolase	Piperidine Sulfur Compound Carboxamide Sulfonyl
CHEMBL2392714	Epoxide_hydrolase	Trifluoro Piperidine Carboxamide Triazine
CHEMBL1615216	Epoxide_hydrolase	Piperidine Urea derivative Cyclopropyl Carboxamide Oxadiazol
TAK-802	ACHE	Piperidine
Z-Pro-Prolinal-derived	S9N_PPCE_Peptidase_S9	Benzyloxycarbonyl Piperidine Peptide Pyrrolidine Carboxamide Carbamate
GSK237826A	Prolylcarboxypeptidase	Piperidine
N-piperidinopropylgalanthamine	ACHE	Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Benzazepin Azepane
24D	Epoxide_hydrolase	Piperidine Pyrimidine Carboxamide
Piperidine-fused-benzimidazole-25	DPP4N_Peptidase_S9	Trifluoro Piperidine Sulfur Compound Imidazole Benzimidazole Sulfonyl
Piperidine-fused-benzimidazole-34	DPP4N_Peptidase_S9	Trifluoro Piperidine Benzimidazole
JJKK-048	Monoglyceridelipase_lysophospholip	Benzodioxo Piperidine Triazol
Gemigliptin	DPP4N_Peptidase_S9	Drug Piperidine Pyrimidine Gliptin Trifluoro
Gosogliptin	DPP4N_Peptidase_S9	Drug Piperidine Pyrimidine Gliptin
Trelagliptin	DPP4N_Peptidase_S9	Drug Piperidine Pyrimidine Cyanide Gliptin
CHEMBL4465514	Epoxide_hydrolase	Piperidine Carboxamide Sulfur Compound Thiophen
5ALH-4UA	Epoxide_hydrolase	Sulfonamide Carboxamide Sulfur Compound Piperidine Sulfonyl
5ALZ-XQ9	Epoxide_hydrolase	Urea derivative Adamantyl Piperidine Sulfur Compound Sulfonyl Sulfonamide
5AM1-I5T	Epoxide_hydrolase	Piperidine Carboxamide Cyclopropyl Chromen
Triazolopiperazine-based-beta-amino-acid	DPP4N_Peptidase_S9	Piperidine Trifluoro Triazol
GVB	DPP4N_Peptidase_S9	Piperidine
Piperidinone-constrained-phenethylamine-31	DPP4N_Peptidase_S9	Benzodioxo Trifluoro Piperidine
Piperidine-constrained-phenethylamine-42	DPP4N_Peptidase_S9	Trifluoro Sulfur Compound Pyrimidine Piperidine
LIR	DPP4N_Peptidase_S9	Cyanide Piperidine Imidazole
Xanthine-inhibitor-4	DPP4N_Peptidase_S9	Pyrimidine Piperidine Cyanide Purine
6Z8	DPP4N_Peptidase_S9	Purine Piperidine Gliptin Peptide
LASSBio-767	ACHE	Natural Derivative of Spectaline Piperidine
LASSBio-822	ACHE	Natural Derivative of Spectaline Piperidine tert-Butyl
CHEMBL4293015	BCHE	Indole Piperidine Derivative of Donepezil Alkyl linked bis-ligand
CB2R-BCHE-x	BCHE	Multitarget Cannabinoid-Receptor-ligand Piperidine Imidazole Carboxamide
CB2R-BCHE-20a	BCHE	Multitarget Cannabinoid-Receptor-ligand Piperidine Imidazole Carboxamide
Contilisant	ACHE BCHE	Multitarget Histamine-Receptor3-H3-Antagonist Monoamine-oxidase-inhibitor Piperidine Indole prop-2-yn-1-yl
ASS234	ACHE	Multitarget Monoamine-oxidase-inhibitor Alkyl linked bis-ligand Piperidine Indole
DL0410	ACHE BCHE	Piperidine Biphenyl
5DYW-5hf-C11	BCHE	Piperidine Derivative of Donepezil Sulfur Compound Sulfonamide PET probe Naphthalen
5DYW-5hf-F	BCHE	Piperidine Derivative of Donepezil Sulfur Compound Sulfonamide PET probe
5DYW-5hf	BCHE	Piperidine Derivative of Donepezil Sulfur Compound Sulfonamide Naphthalen
5NN0-cpd3	BCHE	Piperidine Inden
6FSE-15	ACHE	Piperidine Piperazine
6FSD-10	ACHE	Piperidine
STK133938	ACHE	Piperidine Piperazine
Mebbpp	ACHE	Derivative of Donepezil Multitarget Sulfur Compound Piperidine
Selenepezil	ACHE	Organoselenium Thiol-reactive Derivative of Donepezil Piperidine
CHEMBL3114611	Epoxide_hydrolase	Cyclopropyl Piperidine Urea derivative Carboxamide
AM6580	Monoglyceridelipase_lysophospholip	Piperazine Piperidine Fluoren Triazol Urea derivative
SA-57	Monoglyceridelipase_lysophospholip	Carbamate Piperidine
MGL-Inhibitor-26	Monoglyceridelipase_lysophospholip	Piperidine Carboxamide Pyrazole
B401	Epoxide_hydrolase	Urea derivative Adamantyl Piperidine
EC5026	Epoxide_hydrolase	Urea derivative Trifluoro Piperidine Drug
CHEMBL1938516	Prolylcarboxypeptidase	Piperidine
CHEMBL1684295	Prolylcarboxypeptidase	Pyrrolidine Imidazole Pyridine Oxadiazol Piperidine Benzimidazole
GTPL9797	PAF-Acetylhydrolase	Trifluoro Piperidine Sulfur Compound Sulfonamide Benzenesulfonamide
Rilapladib	PAF-Acetylhydrolase	Trifluoro Piperidine Sulfur Compound
UAMC00039	Prolylcarboxypeptidase	Piperidine
Alogliptin	DPP4N_Peptidase_S9	Drug Piperidine Pyrimidine Cyanide Gliptin
Sitagliptin	DPP4N_Peptidase_S9	Drug Piperidine Gliptin Triazol Trifluoro
CHEMBL238787	Hormone-sensitive_lipase_like Carb_B_Chordata ABHD6-Lip	Trifluoro Carbamate Piperidine
BAY-59-9435	Hormone-sensitive_lipase_like	Piperidine Urea derivative
JZL184	Monoglyceridelipase_lysophospholip Carb_B_Chordata ABHD6-Lip	Piperidine Benzodioxo FAAH inhibitor Multitarget pNP
64D	Monoglyceridelipase_lysophospholip	Piperidine PET probe Sulfonyl Sulfur Compound
KML29	Monoglyceridelipase_lysophospholip Plasmodium_subtelomeric_PST-A	Halo ketone Piperidine Benzodioxo Carbamate Trifluoro
KT195	ABHD6-Lip	Piperidine Biphenyl Triazol
KT172	Lipase_3 Carb_B_Chordata ABHD6-Lip	Piperidine Biphenyl Triazol
KT109	Lipase_3 Carb_B_Chordata ABHD6-Lip	Piperidine Biphenyl Triazol
WWL229	Carb_B_Chordata	pNP Carbamate Piperidine
C7653	ACHE	Piperidine Derivative of Donepezil
4-piperidino-piperidine	Carb_B_Chordata	Leaving group Derivative of Irinotecan Piperidine
40V	BCHE	Piperidine Quinoline Multitarget Carboxamide Metal ion chelator Inden
3F9	BCHE	Piperidine Inden Carboxamide Naphthalen
T-82(1)	ACHE	Piperidine Quinoline
Aricept~Donepezil~E2020	ACHE	Derivative of Donepezil Piperidine Drug Inden
Biscarbamate-Cpd16	BCHE	Derivative of Bambuterol Carbamate Piperidine
KW-5092	ACHE	Piperidine Imidazole
Meperidine	BCHE Carboxylesterase Carb_B_Chordata	Piperidine Drug Not A\/B H target Opioid analgesic
Fluoro-piperidin-ethyl-carbazole-15g	BCHE	Piperidine Carbazol
Ethylpiperidinyl-ethyl-indole-Cpd19	BCHE	Indole Piperidine Natural
N-benzylpiperidine-carbazol-9c	BCHE	Piperidine Carbazol Derivative of Donepezil Multitarget
Pitofenone	ACHE	Piperidine Benzoate
TAK-147	ACHE	Piperidine Derivative of Donepezil Transition state analogue Benzazepin
Icopezil	ACHE	Piperidine Derivative of Donepezil
Vecuronium	BCHE	Neuromuscular Nondepolarizing Agents Nicotinic antagonist Aminosteroid Piperidine Drug Acetate Not A\/B H target